BGC0000006 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000006 (Aspergillus flavus)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	88,318	aflatoxin	Polyketide	100%

BGC0000006 - Region 1 - T1PKS

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Location: 1 - 88,318 nt. (total: 88,318 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 88,319
Label		BGC0000006

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000010.1	0.55	Polyketide	aflatoxin	Aspergillus flavus
BGC0000006.1	0.45	Polyketide	aflatoxin	Aspergillus flavus
BGC0000008.1	0.44	Polyketide	aflatoxin	Aspergillus flavus
BGC0000004.1	0.42	Polyketide	aflatoxin G1	Aspergillus oryzae
BGC0000007.1	0.32	Polyketide	aflatoxin	Aspergillus flavus
BGC0000009.1	0.30	Polyketide	aflatoxin	Aspergillus nomius
BGC0001068.1	0.23	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0000107.1	0.22	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001542.1	0.22	Polyketide	cercosporin	Cercospora zeina
BGC0000030.1	0.22	Polyketide	bikaverin	Fusarium fujikuroi IMI 58289

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000010.1	0.93	Polyketide	aflatoxin	Aspergillus flavus
BGC0000006.1	0.87	Polyketide	aflatoxin	Aspergillus flavus
BGC0000008.1	0.83	Polyketide	aflatoxin	Aspergillus flavus
BGC0000004.1	0.82	Polyketide	aflatoxin G1	Aspergillus oryzae
BGC0000005.1	0.79	Polyketide	aflatoxin	Aspergillus parasiticus
BGC0000007.1	0.76	Polyketide	aflatoxin	Aspergillus flavus
BGC0000009.1	0.74	Polyketide	aflatoxin	Aspergillus nomius
BGC0001858.1	0.60	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001909.1	0.56	Polyketide	strobilurin	Strobilurus tenacellus

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 43732:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pksA

PKS_AT (904..1198): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; Methoxymalonyl-CoA: 58.3%; Isobutyryl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 115.5
inactive: 66.2
Methoxymalonyl-CoA: 53.6
Methylmalonyl-CoA: 46.5
Isobutyryl-CoA: 26.8
Propionyl-CoA: 20.6
Acetyl-CoA: 15.5
fatty_acid: 15.4
2-Methylbutyryl-CoA: 14.9
Benzoyl-CoA: 12.3
CHC-CoA: 11.5
Ethylmalonyl-CoA: 10.2
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0

AAS90095.1

PKS_AT (138..338): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

PKS_AT (1517..1708): pk

ATSignature: (unknown)

No matches above 50%

minowa: trans-1,2-CPDA

Prediction, score:

trans-1,2-CPDA: 0.0
inactive: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Methylmalonyl-CoA: 0.0
Methoxymalonyl-CoA: 0.0
Malonyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0