BGC0000033: calicheamicin biosynthetic gene cluster from Micromonospora echinospora
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Location: 1 - 90,348 nt. (total: 90,348 nt).
This entry is originally from NCBI GenBank AF497482.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000033
Short description calicheamicin biosynthetic gene cluster from Micromonospora echinospora
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AF497482.1
Compounds
  • calicheamicin
Species Micromonospora echinospora [taxonomy]
References
Chemical products information
calicheamicin
Copy SMILES
C55H74I1N3O21S4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAM94759.1
  • calU1
 1 - 873 (+) CalU1
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  • AAM94760.1
  • calU2
 880 - 1827 (+) CalU2
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  • AAM94761.1
  • calU3
 1874 - 2935 (+) CalU3
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  • AAM94762.1
  • calU4
 2932 - 3726 (+) CalU4
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  • AAM94763.1
  • calE1
 3723 - 5048 (+) CalE1
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  • AAM94764.1
  • calU5
 5045 - 5941 (+) CalU5
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  • AAM94765.1
  • calT1
 6006 - 7595 (-) CalT1
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  • AAM94766.1
  • calR1
 7665 - 8285 (-) CalR1
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  • AAM94767.1
  • calU6
 8447 - 9382 (+) CalU6
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  • AAM94768.1
  • calS1
 9415 - 9987 (-) CalS1
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  • AAM94769.1
  • calS2
 10158 - 11081 (+) CalS2
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  • AAM94770.1
  • calS3
 11078 - 12109 (+) CalS3
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  • AAM94771.1
  • calU7
 12161 - 12490 (-) CalU7
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  • AAM94772.1
  • calS4
 12764 - 13918 (+) CalS4
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  • AAM94773.1
  • calE2
 14103 - 15017 (+) CalE2
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  • AAM94774.1
  • calS5
 15028 - 16092 (-) CalS5
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  • AAM94775.1
  • calU8
 16249 - 16962 (+) CalU8
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  • AAM94776.1
  • calS6
 16890 - 17672 (-) CalS6
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  • AAM94777.1
  • calR2
 17960 - 19825 (+) CalR2
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  • AAM94778.1
  • calE3
 19901 - 20794 (+) CalE3
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  • AAM94779.1
  • calU9
 20791 - 21426 (+) CalU9
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  • AAM94780.1
  • calR3
 21423 - 22826 (+) CalR3
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  • AAM94781.1
  • calT2
 22968 - 24506 (-) CalT2
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  • AAM94782.1
  • calR4
 24503 - 26896 (-) CalR4
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  • AAM94783.1
  • calU10
 27102 - 28304 (-) CalU10
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  • AAM94784.1
  • calR5
 28696 - 30072 (-) CalR5
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  • AAM94785.1
  • calR6
 30069 - 31592 (-) CalR6
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  • AAM94786.1
  • calE4
 31589 - 32797 (-) CalE4
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  • AAM94787.1
  • calU11
 32854 - 33672 (-) CalU11
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  • AAM94788.1
  • calE5
 33669 - 34553 (-) CalE5
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  • AAM94789.1
  • calS7
 34687 - 35580 (-) CalS7
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  • AAM94790.1
  • calU12
 35749 - 36411 (+) CalU12
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  • AAM94791.1
  • calU13
 36452 - 37111 (-) CalU13
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  • AAM94792.1
  • calE6
 37168 - 38313 (-) CalE6
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  • AAM94793.1
  • calE7
 38310 - 38756 (-) CalE7
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  • AAM94794.1
  • calE8
 38753 - 44512 (-) CalE8
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  • AAM94795.1
  • calT3
 44509 - 45474 (-) CalT3
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  • AAM70329.1
  • calU14
 45471 - 47426 (-) CalU14
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  • AAM70330.1
  • calU15
 47448 - 48416 (-) CalU15
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  • AAM70331.1
  • calR7
 48717 - 49559 (+) CalR7
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  • AAM70332.1
  • calS8
 49636 - 50997 (+) CalS8
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  • AAM70333.1
  • calS9
 51004 - 51993 (+) CalS9
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  • AAM70334.1
  • calS10
 52213 - 52950 (-) CalS10
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  • AAM70335.1
  • calR8
 53061 - 53453 (+) CalR8
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  • AAM70336.1
  • calG1
 53511 - 54689 (-) CalG1
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  • AAM70337.1
  • calS11
 54904 - 55677 (+) CalS11
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  • AAM70338.1
  • calC
 55857 - 56402 (+) CalC
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  • AAM70339.1
  • calU16
 56411 - 56959 (+) CalU16
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  • AAM70340.1
  • calT4
 57266 - 58108 (-) CalT4
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  • AAM70341.1
  • calT5
 58105 - 59091 (-) CalT5
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  • AAM70342.1
  • calT6
 59208 - 60914 (-) CalT6
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  • AAM70343.1
  • calO1
 60938 - 61975 (-) CalO1
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  • AAM94796.1
  • calE9
 62177 - 63463 (+) CalE9
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  • AAM70345.1
  • IS
 63477 - 64685 (-) IS
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  • AAM70346.1
  • calT7
 64779 - 66461 (+) CalT7
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  • AAM70347.1
  • calR9
 66458 - 67705 (+) CalR9
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  • AAM70348.1
  • calG2
 67788 - 68981 (-) CalG2
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  • AAM70349.1
  • calS12
 69032 - 70024 (-) CalS12
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  • AAM94797.1
  • calS13
 70221 - 71351 (+) CalS13
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  • AAM94798.1
  • calG3
 71392 - 72522 (+) CalG3
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  • AAM94799.1
  • calO2
 72606 - 73799 (+) CalO2
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  • AAM70353.1
  • calO3
 73840 - 75102 (+) CalO3
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  • AAM70354.1
  • calO4
 75152 - 76186 (+) CalO4
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  • AAM70355.1
  • calO5
 76231 - 80046 (+) CalO5
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  • AAM70356.1
  • calO6
 80077 - 81147 (+) CalO6
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  • AAM70357.1
  • calU17
 81152 - 82102 (+) CalU17
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  • AAM70358.1
  • calU18
 82105 - 82371 (+) CalU18
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  • AAM70359.1
  • calS14
 82456 - 83886 (+) CalS14
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  • AAM94800.1
  • calE10
 84045 - 85229 (+) CalE10
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  • AAM70361.1
  • calU19
 85300 - 85998 (-) CalU19
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  • AAM70362.1
  • calU20
 86118 - 86669 (-) CalU20
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  • AAM70363.1
  • calU21
 86678 - 87271 (-) CalU21
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  • AAM94801.1
  • calU22
 87351 - 88853 (-) CalU22
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  • AAM70365.1
  • calG4
 89143 - 90348 (-) CalG4
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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