LOCUS       BGC0000068             28356 bp    DNA     linear   BCT 14-JUL-2016
DEFINITION  Streptomyces hygroscopicus strain 17997 geldanamycin biosynthesis
            gene cluster, partial sequence.
ACCESSION   BGC0000068
VERSION     BGC0000068
KEYWORDS    .
SOURCE      Streptomyces hygroscopicus
  ORGANISM  Streptomyces hygroscopicus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces; Streptomyces violaceusniger group.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 15:28:29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 28356
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..9163
                     /allele="gdmAIII"
                     /gene="gdmPKS"
     source          1..28356
                     /db_xref="taxon:1912"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces hygroscopicus"
                     /strain="17997"
     misc_feature    <1..>28356
                     /note="geldanamycin biosynthesis gene cluster"
     protocluster    1..28356
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<1:9163]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      <2..9163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     cand_cluster    1..28356
                     /SMILES="C(C)=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     or strH or strK1 or strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="amglyccycl"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..28356
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000068"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..28356
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="amglyccycl"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) or strH or
                     strK1 or strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..9163
                     /NRPS_PKS="Domain: PKS_DH (141-302). E-value: 2.8e-59.
                     Score: 192.0. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (604-905). E-value: 1e-108.
                     Score: 355.0. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (914-1094). E-value: 1.3e-59.
                     Score: 193.0. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1184-1270). E-value: 1.4e-31.
                     Score: 100.5. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1295-1721). E-value:
                     1.1e-180. Score: 593.0. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1836-2133). E-value: 9.5e-107.
                     Score: 348.6. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (2199-2362). E-value: 6.2e-61.
                     Score: 197.4. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_DH.2"
                     /NRPS_PKS="Domain: PKS_KR (2669-2848). E-value: 2.3e-60.
                     Score: 195.5. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (2943-3029). E-value: 1e-30.
                     Score: 97.7. Matches aSDomain:
                     nrpspksdomains_gdmPKS_PKS_PP.2"
                     /allele="gdmAIII"
                     /codon_start=2
                     /gene="gdmPKS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 90.9; E-value:
                     1.2e-27)"
                     /gene_kind="biosynthetic"
                     /note="polyketide synthase modules 6-7; gdmAIII"
                     /product="GdmPKS"
                     /protein_id="ABI93779.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.3e-107, bitscore:
                     348.6, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1e-227, bitscore: 745.7,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.4e-64, bitscore:
                     204.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 5e-10, bitscore: 29.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="DPEELCSPEYWVRHVRGAVRFLDGVRTLADEGVRTHLELGPDGVL
                     TAMGQDCLPDAGAEADTAFAAFVPSLRPGVQEAHATLAGLAGLYVRGVPVDWDAMFAGS
                     GARRVDLPTYAFQHEHYWLERPAGSGDVGAVGLGAAGHPLLGAVVQLPETGGVQLSGRL
                     SVRAQPWLGEHIISGTVLVPGTAMVELAVRAGDETGTPVLEELVIGQPMLLPGDTALSV
                     QVVVGTDEGGRRTVRIYSRADGATDWTEHATGTLMAQGPAPLDGATGEWPPAEAEPIPV
                     EDFYRSLVDAGYAYGPAFRGLAAAWRLDGEVFGEVALPETYAEEAERFGIHPALLDAAL
                     HAGNFCLPSDPARQVTLLPFAWNNVRLYAGGASAVRVQVRPAGDDAFSVRLTDGSGRTV
                     ASVEALTLRAVDPAQLETNTADDALWTVRWSEHPLPDGTVSWAPLGEAAAGSDTATEGT
                     LPDVLVADTRTWAEDLTEPLPARARELTGRLLEEIQRWVTDDAMAGTRLAVVTRGAVAV
                     HGDAEVTDPAAAAVWGLVRSAQAEHPGRLALVDADGACEELPAGVWSGDEPQLAVRGGT
                     VWVPRLARVEPGLRVPEQRSWHLDSAEYGTLDNLALLPDEARTAPLEAGQVRIEVRAAG
                     LNFRDVLVALGMYPGRSVIGTEGAGVVTEVGPDVADLAVGDRVMGLFSGSFGPLATADA
                     RTVIRMPEGWSFGTAAGVPVAYLTALYALQDLGKVRPGETVLVHAAAGGVGMAAVQLAQ
                     HLGATVLGTAHPSKHHALHRLGVPAERLASSRDLGYAGTFPTADVVLNSLTGEHIDASL
                     GLLGPGGRFLEMGKTDLREPGEVGARHPEVTYRAFDLGGEAPADRVRELLRQLVELFEA
                     GRIEPLPVRHWDITRAPEAFRWMSQGRHTGKIVLTIPRTLDPDGTVLVTGGTGTLGATI
                     ARHLITHHGARHLLLVSRQGPDAPGATELATELSELGATVHITACDTADRHHLTTTLAN
                     IPPDHPLTAVIHTAGTLDDGILTALTPLRLDTVFRPKIDAVTHLHDLTRDQDLAAFVVY
                     SSAAGVLGGPGQGNYSAANAYLDGLAQWRRARGLPATSLAWGMWAETSGMTAGLGSGDL
                     HRVRRGGIVGLSTAEALDLFDRSVASGLSLLMPLRFDFAALGAEATEPPPLLRGLVRPA
                     RRTARPVPKAAEGGLVQRLAGLATAEQQRLLVELTREETASVLGFPTVDPIGPEQAFRD
                     LGIDSLTAVELRNRLNTATGLRLPATLVFDHPTPQATAEFLRDQLGGRTVEAAPRPTHR
                     RRSAPDEAEDPVVVVGMGCRLPGDVRTPEDLWRLVAAGTDAIGPFPQDRGWDLAGLFDP
                     DPDAVGKSYVREGGFLTDAGGFDAAFFGISPREALSMDPQQRVLLETAWETLEGSGIVP
                     TSLRGQEVGVFVGASGQGYGTGPGAAPEGLEGYLGVGGATSVASGRVSYTFGLTGPAVT
                     VDTACSSSLVAIHLAVQALRSGECTMALAGGVAVMGQPGAFVEFSRQRGLASDGRCKSF
                     GEGADGTNWSEGVGLLLLERLSDARRDGHEVLAVIRGTAVNQDGASNGLTAPNGPSQQR
                     VIRQALANAGLTAADVDAVEAHGTGTALGDPIEAQALLATYGQERQGDEPLWLGSLKSN
                     IGHTQAAAGVSSVIKMVLALRHSTLPRSLHADEPTAQVDWTSGAVSLLAEARPWPVNGH
                     PRRAGISSFGVSGTNAHVVLEQAPNPEPAPKVDDGTEIPGLVATGGIAPWVLSAKTATA
                     LRAQAQCLLDHLESGADAHPVDIGWSLATTRTLHDHRAVILADTTAESTETTAALTALA
                     SGQPHPRLTTGHATTHGKTAFVFPGQGAQWVGMGAQLLTTSPVFAERLHECAAALAPYT
                     DWNLIDVITGAPDAPSLDRVDVVQPATFAVVVSLAALWQSCGIHPDAVIGHSQGEIAAA
                     CVAGHLTLPTAAKIITLRSQTIAHHLAGHGGMMSLAAPADTIDLTNWHGKLWIAAHNGP
                     NATVIAGDTDALHELHAHYTDQGIRARIIPVDYASHTGHVDTIEDELHQALADTTTEPG
                     TIPWLSTVTGQWIEPNTADGDYWFRNLRQTVRFDATVRTLADDGYRTFIEVSPHPVLTT
                     AIQETLEANQTPHTTITGTLRRNDDTPTRFLTHLAELSTRGTPMDWPTAYTGSQPSQIP
                     LPTYPFQHETFWLDRGGPGDVRAVGLEDTGHPLVGAVVSVPDTGGVLLTGRLSLPTHPW
                     LADHAVSGTVLLPGTAMVELAVRAGDEADTPVLEELVISRPMTVPDEGTLHVQVLVGGE
                     ERGRRKVGVYSRPEGIREWTEHATGTLTAGAAVPPEEAEAALPWPPEGAEPVALEGFYE
                     HLAEVGYEYGPAFRGLRAVWKRDDEVFAEVSVPEEQTGVAGRFGIHPALLDATLHAGNF
                     CFQSAGERPTMLPFAWTDVRLHAVGATAVRVRATVSGGDGLCVRITDPRGVPVATIGSL
                     QLRETTPDQLRALAAASGGNALWAVEWAECGLGATEARWATVGESGLPDAPSSYADVPE
                     VAEAGERPEVLVADVSAWVPEQTGPIDRTHALCARVLDLLREWVDRPELADTRLAVLTR
                     GAMAVHDTAEVTDPAAAAVWGLVRSAQSEHPGRVRLIDVDGHSHQTLPTALTTAEAQLA
                     LRDTTAYTPHLTAAPTGTPSQPLALAPEGTVLITGGTGTLGALTARHLITQHGARDLLL
                     VSRQGPDAPGAARLGEELTRLGARIHIAACDTADRDQLAAVLDGIPADHPLTAVVHTAG
                     TLDDALLTDLTPRRLDTVLRPKVDALTHLHDLTRDLDLAAFVVFSSATGVLGTPGQANY
                     AAANTYADALAQQRHAAGLPATSLAWGLWETTSALTAGMTTAQQQRTRHSGVIPLTDAD
                     GMRLLDTALTTPHPHLIPLELDLAALRNNTDPHTLPPLLRGLIRGHHRPTAHASARPDA
                     APSLAQELAALDPAQRHQRLTELVRAEAAAVLGHPTPDAVGPNDPLFEIGFDSLTAVEL
                     RNRLNAATGLQLAAAMLFDYPTPSMAAEHLQEQLALDATNAPVAAREAAEDDDQNTER"
     CDS_motif       29..64
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0001"
                     /evalue="4.20E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="gdmPKS"
                     /protein_end="21"
                     /protein_start="9"
                     /score="13.8"
                     /tool="antismash"
                     /translation="YWVRHVRGAVRF"
     aSDomain        425..907
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_DH.1"
                     /evalue="2.80E-59"
                     /label="gdmPKS_PKS_DH.1"
                     /locus_tag="gdmPKS"
                     /protein_end="302"
                     /protein_start="141"
                     /score="192.0"
                     /tool="antismash"
                     /translation="HPLLGAVVQLPETGGVQLSGRLSVRAQPWLGEHIISGTVLVPGTA
                     MVELAVRAGDETGTPVLEELVIGQPMLLPGDTALSVQVVVGTDEGGRRTVRIYSRADGA
                     TDWTEHATGTLMAQGPAPLDGATGEWPPAEAEPIPVEDFYRSLVDAGYAYGPAFRGL"
     aSModule        425..3811
                     /domains="nrpspksdomains_gdmPKS_PKS_DH.1"
                     /domains="nrpspksdomains_gdmPKS_PKS_ER.1"
                     /domains="nrpspksdomains_gdmPKS_PKS_KR.1"
                     /domains="nrpspksdomains_gdmPKS_PKS_PP.1"
                     /incomplete
                     /locus_tags="gdmPKS"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       509..583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0002"
                     /evalue="3.80E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="gdmPKS"
                     /protein_end="194"
                     /protein_start="169"
                     /score="25.8"
                     /tool="antismash"
                     /translation="WLGEHIISGTVLVPGTAMVELAVRA"
     CDS_motif       875..907
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0003"
                     /evalue="4.80E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="gdmPKS"
                     /protein_end="302"
                     /protein_start="291"
                     /score="7.0"
                     /tool="antismash"
                     /translation="GYAYGPAFRGL"
     aSDomain        1814..2716
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_ER.1"
                     /evalue="1.00E-108"
                     /label="gdmPKS_PKS_ER.1"
                     /locus_tag="gdmPKS"
                     /protein_end="905"
                     /protein_start="604"
                     /score="355.0"
                     /tool="antismash"
                     /translation="GTLDNLALLPDEARTAPLEAGQVRIEVRAAGLNFRDVLVALGMYP
                     GRSVIGTEGAGVVTEVGPDVADLAVGDRVMGLFSGSFGPLATADARTVIRMPEGWSFGT
                     AAGVPVAYLTALYALQDLGKVRPGETVLVHAAAGGVGMAAVQLAQHLGATVLGTAHPSK
                     HHALHRLGVPAERLASSRDLGYAGTFPTADVVLNSLTGEHIDASLGLLGPGGRFLEMGK
                     TDLREPGEVGARHPEVTYRAFDLGGEAPADRVRELLRQLVELFEAGRIEPLPVRHWDIT
                     RAPEAFRWMSQGRHTGKIVL"
     CDS_motif       1904..1939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0004"
                     /evalue="4.60E-04"
                     /label="PKSI-ER_m1"
                     /locus_tag="gdmPKS"
                     /protein_end="646"
                     /protein_start="634"
                     /score="13.1"
                     /tool="antismash"
                     /translation="GLNFRDVLVALG"
     CDS_motif       1961..1999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0005"
                     /evalue="3.40E-02"
                     /label="PKSI-ER_m2"
                     /locus_tag="gdmPKS"
                     /protein_end="666"
                     /protein_start="653"
                     /score="7.5"
                     /tool="antismash"
                     /translation="IGTEGAGVVTEVG"
     CDS_motif       2126..2170
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0006"
                     /evalue="6.40E-04"
                     /label="PKSI-ER_m4"
                     /locus_tag="gdmPKS"
                     /protein_end="723"
                     /protein_start="708"
                     /score="13.2"
                     /tool="antismash"
                     /translation="AAGVPVAYLTALYAL"
     CDS_motif       2195..2257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0007"
                     /evalue="2.90E-09"
                     /label="PKSI-ER_m5"
                     /locus_tag="gdmPKS"
                     /protein_end="752"
                     /protein_start="731"
                     /score="29.2"
                     /tool="antismash"
                     /translation="GETVLVHAAAGGVGMAAVQLA"
     CDS_motif       2669..2716
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0008"
                     /evalue="2.20E-06"
                     /label="PKSI-ER_m9"
                     /locus_tag="gdmPKS"
                     /protein_end="905"
                     /protein_start="889"
                     /score="20.5"
                     /tool="antismash"
                     /translation="AFRWMSQGRHTGKIVL"
     aSDomain        2744..3283
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_KR.1"
                     /evalue="1.30E-59"
                     /label="gdmPKS_PKS_KR.1"
                     /locus_tag="gdmPKS"
                     /protein_end="1094"
                     /protein_start="914"
                     /score="193.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGGTGTLGATIARHLITHHGARHLLLVSRQGPDAPGATEL
                     ATELSELGATVHITACDTADRHHLTTTLANIPPDHPLTAVIHTAGTLDDGILTALTPLR
                     LDTVFRPKIDAVTHLHDLTRDQDLAAFVVYSSAAGVLGGPGQGNYSAANAYLDGLAQWR
                     RARGLPATSLAWGMWAE"
     CDS_motif       2747..2845
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0009"
                     /evalue="5.10E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="gdmPKS"
                     /protein_end="948"
                     /protein_start="915"
                     /score="32.0"
                     /tool="antismash"
                     /translation="TVLVTGGTGTLGATIARHLITHHGARHLLLVSR"
     CDS_motif       3128..3235
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0010"
                     /evalue="6.20E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="gdmPKS"
                     /protein_end="1078"
                     /protein_start="1042"
                     /score="60.6"
                     /tool="antismash"
                     /translation="AAFVVYSSAAGVLGGPGQGNYSAANAYLDGLAQWRR"
     aSDomain        3554..3811
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_PP.1"
                     /evalue="1.40E-31"
                     /label="gdmPKS_PKS_PP.1"
                     /locus_tag="gdmPKS"
                     /protein_end="1270"
                     /protein_start="1184"
                     /score="100.5"
                     /tool="antismash"
                     /translation="LAGLATAEQQRLLVELTREETASVLGFPTVDPIGPEQAFRDLGID
                     SLTAVELRNRLNTATGLRLPATLVFDHPTPQATAEFLRDQL"
     aSDomain        3887..5164
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_KS.1"
                     /domain_subtype="Modular-KS"
                     /evalue="1.10E-180"
                     /label="gdmPKS_PKS_KS.1"
                     /locus_tag="gdmPKS"
                     /protein_end="1721"
                     /protein_start="1295"
                     /score="593.0"
                     /tool="antismash"
                     /translation="VVVVGMGCRLPGDVRTPEDLWRLVAAGTDAIGPFPQDRGWDLAGL
                     FDPDPDAVGKSYVREGGFLTDAGGFDAAFFGISPREALSMDPQQRVLLETAWETLEGSG
                     IVPTSLRGQEVGVFVGASGQGYGTGPGAAPEGLEGYLGVGGATSVASGRVSYTFGLTGP
                     AVTVDTACSSSLVAIHLAVQALRSGECTMALAGGVAVMGQPGAFVEFSRQRGLASDGRC
                     KSFGEGADGTNWSEGVGLLLLERLSDARRDGHEVLAVIRGTAVNQDGASNGLTAPNGPS
                     QQRVIRQALANAGLTAADVDAVEAHGTGTALGDPIEAQALLATYGQERQGDEPLWLGSL
                     KSNIGHTQAAAGVSSVIKMVLALRHSTLPRSLHADEPTAQVDWTSGAVSLLAEARPWPV
                     NGHPRRAGISSFGVSGTNAHVVLEQAP"
     aSModule        3887..9088
                     /complete
                     /domains="nrpspksdomains_gdmPKS_PKS_KS.1"
                     /domains="nrpspksdomains_gdmPKS_PKS_AT.1"
                     /domains="nrpspksdomains_gdmPKS_PKS_DH.2"
                     /domains="nrpspksdomains_gdmPKS_PKS_KR.2"
                     /domains="nrpspksdomains_gdmPKS_PKS_PP.2"
                     /locus_tags="gdmPKS"
                     /monomer_pairings="mmal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       4370..4417
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0011"
                     /evalue="1.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="gdmPKS"
                     /protein_end="1472"
                     /protein_start="1456"
                     /score="20.0"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       4793..4837
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0012"
                     /evalue="9.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="gdmPKS"
                     /protein_end="1612"
                     /protein_start="1597"
                     /score="11.6"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     CDS_motif       4898..4942
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0013"
                     /evalue="4.20E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="gdmPKS"
                     /protein_end="1647"
                     /protein_start="1632"
                     /score="9.9"
                     /tool="antismash"
                     /translation="GSLKSNIGHTQAAAG"
     CDS_motif       5507..5560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0014"
                     /evalue="2.50E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="gdmPKS"
                     /protein_end="1853"
                     /protein_start="1835"
                     /score="25.7"
                     /tool="antismash"
                     /translation="FVFPGQGAQWVGMGAQLL"
     aSDomain        5510..6400
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_AT.1"
                     /evalue="9.50E-107"
                     /label="gdmPKS_PKS_AT.1"
                     /locus_tag="gdmPKS"
                     /protein_end="2133"
                     /protein_start="1836"
                     /score="348.6"
                     /specificity="consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGAQWVGMGAQLLTTSPVFAERLHECAAALAPYTDWNLIDV
                     ITGAPDAPSLDRVDVVQPATFAVVVSLAALWQSCGIHPDAVIGHSQGEIAAACVAGHLT
                     LPTAAKIITLRSQTIAHHLAGHGGMMSLAAPADTIDLTNWHGKLWIAAHNGPNATVIAG
                     DTDALHELHAHYTDQGIRARIIPVDYASHTGHVDTIEDELHQALADTTTEPGTIPWLST
                     VTGQWIEPNTADGDYWFRNLRQTVRFDATVRTLADDGYRTFIEVSPHPVLTTAIQETLE
                     ANQTPHTTITGTLRRN"
     CDS_motif       5672..5743
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0015"
                     /evalue="2.30E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="gdmPKS"
                     /protein_end="1914"
                     /protein_start="1890"
                     /score="29.4"
                     /tool="antismash"
                     /translation="LDRVDVVQPATFAVVVSLAALWQS"
     CDS_motif       5747..5857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0016"
                     /evalue="1.80E-16"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="gdmPKS"
                     /protein_end="1952"
                     /protein_start="1915"
                     /score="52.0"
                     /tool="antismash"
                     /translation="GIHPDAVIGHSQGEIAAACVAGHLTLPTAAKIITLRS"
     CDS_motif       5960..5998
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0017"
                     /evalue="4.30E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="gdmPKS"
                     /protein_end="1999"
                     /protein_start="1986"
                     /score="10.5"
                     /tool="antismash"
                     /translation="AAHNGPNATVIAG"
     CDS_motif       6068..6100
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0018"
                     /evalue="7.00E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="gdmPKS"
                     /protein_end="2033"
                     /protein_start="2022"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VDYASHTGHVD"
     CDS_motif       6209..6253
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0019"
                     /evalue="1.00E-04"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="gdmPKS"
                     /protein_end="2084"
                     /protein_start="2069"
                     /score="14.6"
                     /tool="antismash"
                     /translation="DGDYWFRNLRQTVRF"
     CDS_motif       6296..6325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0020"
                     /evalue="7.20E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="gdmPKS"
                     /protein_end="2108"
                     /protein_start="2098"
                     /score="9.2"
                     /tool="antismash"
                     /translation="FIEVSPHPVL"
     aSDomain        6599..7087
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_DH.2"
                     /evalue="6.20E-61"
                     /label="gdmPKS_PKS_DH.2"
                     /locus_tag="gdmPKS"
                     /protein_end="2362"
                     /protein_start="2199"
                     /score="197.4"
                     /tool="antismash"
                     /translation="HPLVGAVVSVPDTGGVLLTGRLSLPTHPWLADHAVSGTVLLPGTA
                     MVELAVRAGDEADTPVLEELVISRPMTVPDEGTLHVQVLVGGEERGRRKVGVYSRPEGI
                     REWTEHATGTLTAGAAVPPEEAEAALPWPPEGAEPVALEGFYEHLAEVGYEYGPAFRGL
                     "
     CDS_motif       6683..6757
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0021"
                     /evalue="4.20E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="gdmPKS"
                     /protein_end="2252"
                     /protein_start="2227"
                     /score="32.0"
                     /tool="antismash"
                     /translation="WLADHAVSGTVLLPGTAMVELAVRA"
     CDS_motif       7055..7087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0022"
                     /evalue="1.50E-02"
                     /label="PKSI-DH_m3"
                     /locus_tag="gdmPKS"
                     /protein_end="2362"
                     /protein_start="2351"
                     /score="8.5"
                     /tool="antismash"
                     /translation="GYEYGPAFRGL"
     CDS_motif       7883..7912
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0023"
                     /evalue="2.30E+01"
                     /label="PKSI-ER_m4"
                     /locus_tag="gdmPKS"
                     /protein_end="2637"
                     /protein_start="2627"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="TLPTALTTAE"
     aSDomain        8009..8545
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_KR.2"
                     /evalue="2.30E-60"
                     /label="gdmPKS_PKS_KR.2"
                     /locus_tag="gdmPKS"
                     /protein_end="2848"
                     /protein_start="2669"
                     /score="195.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGTLGALTARHLITQHGARDLLLVSRQGPDAPGAARL
                     GEELTRLGARIHIAACDTADRDQLAAVLDGIPADHPLTAVVHTAGTLDDALLTDLTPRR
                     LDTVLRPKVDALTHLHDLTRDLDLAAFVVFSSATGVLGTPGQANYAAANTYADALAQQR
                     HAAGLPATSLAWGLWE"
     CDS_motif       8012..8110
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0024"
                     /evalue="1.90E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="gdmPKS"
                     /protein_end="2703"
                     /protein_start="2670"
                     /score="30.2"
                     /tool="antismash"
                     /translation="TVLITGGTGTLGALTARHLITQHGARDLLLVSR"
     CDS_motif       8393..8500
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_gdmPKS_0025"
                     /evalue="7.80E-19"
                     /label="PKSI-KR_m4"
                     /locus_tag="gdmPKS"
                     /protein_end="2833"
                     /protein_start="2797"
                     /score="60.2"
                     /tool="antismash"
                     /translation="AAFVVFSSATGVLGTPGQANYAAANTYADALAQQRH"
     aSDomain        8831..9088
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmPKS_PKS_PP.2"
                     /evalue="1.00E-30"
                     /label="gdmPKS_PKS_PP.2"
                     /locus_tag="gdmPKS"
                     /protein_end="3029"
                     /protein_start="2943"
                     /score="97.7"
                     /tool="antismash"
                     /translation="LAALDPAQRHQRLTELVRAEAAAVLGHPTPDAVGPNDPLFEIGFD
                     SLTAVELRNRLNAATGLQLAAAMLFDYPTPSMAAEHLQEQL"
     gene            9172..9945
                     /gene="gdmF"
     CDS             9172..9945
                     /codon_start=1
                     /gene="gdmF"
                     /note="amide synthase; rifF"
                     /product="GdmF"
                     /protein_id="ABI93780.1"
                     /transl_table=11
                     /translation="MFDVAKYLRRIGVESIPAPTLDTLRHLHKRHLMAVPYDNSTAPDR
                     LPASRHLTNVPLDLVFEHVVTEGHGGVCYELNRLFHTLLAELGYDVRMVAAAVRQANGA
                     FGPEREHTFDLVRLDGRTHLVDVGFPGPSYSEPLRLSEEEQHQYGCAYRVTEHDGYRVV
                     ERRPKESGWQPVYRFRPELADPSGWDAVRLDSLDDYAQDSVLAGTTFRSRATDNGKIVL
                     IGRRCFTVEDGVERTKVLVKADEFQDTVDLILAGE"
     gene            9942..11585
                     /gene="gdmM"
     CDS             9942..11585
                     /codon_start=1
                     /gene="gdmM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 376.9; E-value:
                     2.9e-114)"
                     /gene_kind="biosynthetic-additional"
                     /note="FAD-dependent monooxygenase; rif19"
                     /product="GdmM"
                     /protein_id="ABI93781.1"
                     /transl_table=11
                     /translation="MSGKETAVDVARDTDNGGPKTDVLIVGYGPVGQLLSVLLAQRGRR
                     VTVVERWPEPYRHPRAVGFDSEAARILASAGIGDSLEKFTEPARDHAWQNTKGETLIDH
                     EVANRGHCTWPEALSAYQPALESALIEHGATLPRLRVLRGYEAVGLADNGDRVTLTVVG
                     PDGERTDLIASWVVGCDGANSLVRASVGTTVTDLDFSYDWLICDVRLHEHREFRPNNLE
                     ICDPARPRTAVSAGPGHRRYEFMRVPADDPAHFGTVESAWELLRLFDVTPDNGVLDRHA
                     VYTFQARWAEHWRAGRLLLAGDSAHLMPPFAGQGMCSGFRDAANLAWKLDLVLSGHAAP
                     ALLDTYTSERRAHVRHAVEMSVGLGRVVCMADPAAAADRDAAMLAARKRNIGPSAARRS
                     VVRPLVDGLLRRDGQGRPAPYAGQAAPQWRVGRAGGTGLFDDVVGTGFILLYGEDVVPA
                     LDARQLTFLDNIGARLVRVVRAETPAADLEPGDARDVEGRYLPYLSEMGALAVLVRPDF
                     YVFGIAGDKAELPSLVDDLAEQLTPTAAPS"
     protocluster    11660..28356
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[21659:22724]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ) or
                     strH or strK1 or strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21660..22724
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ) or
                     strH or strK1 or strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /neighbourhood="10000"
                     /product="amglyccycl"
                     /protocluster_number="2"
     cand_cluster    11660..28356
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     or strH or strK1 or strK2 or NeoL or SpcFG or SpcDK_glyc)"
                     /kind="single"
                     /product="amglyccycl"
                     /protoclusters="2"
                     /tool="antismash"
     gene            complement(12079..14130)
                     /gene="gdmN"
     CDS             complement(12079..14130)
                     /codon_start=1
                     /gene="gdmN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /note="carbamoyltransferase; hbmN"
                     /product="GdmN"
                     /protein_id="ABI93782.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 3.4e-44,
                     bitscore: 141.4, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGLNGNFSAADTDVVPRLSEVFFHDSAASLIRDGELVAAVEEER
                     LNRIKKTTKFPINAVRECLALAGARPEDVDAVGYYFPENHIDTVLNHLYTEYPRVPLRY
                     SRELIRERLKEGLDWDLPEDKLVYVPHHEAHAYSTYLHSGMDSALVLVLDGRGELHSGT
                     VYRAEGTHLERLADYPVPKSLGGLYLNATYLLGYGFGDEYKVMGLAPWGDPATYRDTFS
                     KLYTLQDNGEYELHGNIMVPNLVSPLFYAEGFRPRRKSEPFTQAHRDFAAALQEAVEKI
                     VLHILQHWAKTSGLSRLCFGGGVAHNSSLNGLILKSGLFDEVFIHPASHDAGAGEGAAY
                     AAAASLGTLQRPRKRLLSASLGPALGTRERIRARLADWAPLIDVEFPGDAVERAAGLLA
                     EGEVLGWAYGRSEFGPRALGHRSIVADARPEENRTRINAMVKKREGFRPFAPVVTAEAA
                     RDYFDLSGAEGNHEFMSFVVPVLPERRTELGAVTHVDGTARVQVVSAASGERFHRLVRR
                     FGELTGTPVLLNTSFNNNAEPIVQSLDDVVTSFLTTDLDALVVEDCLVRAKPSPDLGVL
                     VPRFRPVTRLVEHRTSGPDASAGTKVHEIHLDYDGGPSAKVSPELYELLGAVDGTTTLG
                     DLAKAVGGLSEALAAEVFALWEQRFLTLVPAGELQPAQGPADDGARGR"
     gene            complement(14198..15310)
                     /gene="gdmH"
     CDS             complement(14198..15310)
                     /NRPS_PKS="Domain: FkbH (14-129). E-value: 5.5e-18. Score:
                     57.0. Matches aSDomain: nrpspksdomains_gdmH_FkbH.1"
                     /codon_start=1
                     /gene="gdmH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1256:FkbH like protein (Score: 466.5; E-value:
                     7e-142)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative methoxymalonyl-ACP; fkbH"
                     /product="GdmH"
                     /protein_id="ABI93783.1"
                     /transl_table=11
                     /translation="MTEGKPVSEPPAAVKCLVWDLDNTLWRGTLLEDGEVPPFAWVRDV
                     ITTLDDRGILQSIASKNDHDHAWARLEALGLAEYFVLPHIGWGPKSESVRAIAERLNFA
                     HRAMAFVDDQPAERAEVGYRLPEVRCYTAEDVAGLTGLPEFSPAVVTVDSRQRRTMYQS
                     GFRRDAERAEFGGPDEEFLRTLDIEMAISRATERELSRVEELTLRTSQMNATGVHYSDS
                     VLRGLLTDPAHEVLVITMADRFGPHGAVGIVLLERHPAVWHLKLLATSCRVVSYGAGST
                     LLNWLADQAARAGVHLAADFRRTDRNRMMEVAYRFAGFADADCACTAALAAPGEEGVER
                     LHLTPAFQPAPTTLRLTAPELADAALPRSR"
     aSDomain        complement(14924..15268)
                     /aSDomain="FkbH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmH_FkbH.1"
                     /evalue="5.50E-18"
                     /label="gdmH_FkbH.1"
                     /locus_tag="gdmH"
                     /protein_end="129"
                     /protein_start="14"
                     /score="57.0"
                     /tool="antismash"
                     /translation="KCLVWDLDNTLWRGTLLEDGEVPPFAWVRDVITTLDDRGILQSIA
                     SKNDHDHAWARLEALGLAEYFVLPHIGWGPKSESVRAIAERLNFAHRAMAFVDDQPAER
                     AEVGYRLPEVR"
     gene            complement(15307..16419)
                     /gene="gdmI"
     CDS             complement(15307..16419)
                     /codon_start=1
                     /gene="gdmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 325.7; E-value:
                     6.5e-99)"
                     /gene_kind="biosynthetic-additional"
                     /note="biosynthesis pathway protein methoxymalonyl-ACP;
                     fkbI"
                     /product="GdmI"
                     /protein_id="ABI93784.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.9e-14, bitscore:
                     43.6, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.3e-22, bitscore:
                     68.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.5e-32, bitscore:
                     102.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAATDHAELVSGLIGDRADAWDLAGELPRDLLVKLGASGVLCA
                     QVGPEHGGTGLDSHANGELTARVGARCSSLRSVMTSQGMAAWTVRRLGGTEQWDTFLPR
                     LTSGDLAAVGFSEPGAGSDLSAMETEIADDGAEVVVTGRKVWITAAHYADLLLVFGKYR
                     GGATAVVVPARTPGVRITRVENPLGCRAAGHANITLDAVRVPAGHVLGGTGLPLSLATT
                     AALTYGRMSVAWGCVGILRACLDAAATHTATREQSGRALAEHQLVARHLAELYVAERHA
                     TRACEHASASWDTGSPDMAVDAVHAKYVASREAAQGAARAVQLLASAGASDGHVVARAY
                     RDAKLMEVIEGTSEICQLVLARHMRKKVRP"
     gene            complement(16416..16691)
                     /gene="gdmJ"
     CDS             complement(16416..16691)
                     /NRPS_PKS="Domain: PP-binding (14-83). E-value: 2.8e-09.
                     Score: 29.3. Matches aSDomain:
                     nrpspksdomains_gdmJ_PP-binding.1"
                     /codon_start=1
                     /gene="gdmJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147:putative acyl carrier protein (Score: 94.3;
                     E-value: 5.5e-29)"
                     /gene_kind="biosynthetic-additional"
                     /note="ACP in methoxymalonyl-ACP biosynthesis pathway;
                     fkbJ"
                     /product="GdmJ"
                     /protein_id="ABI93785.1"
                     /sec_met_domain="PP-binding (E-value: 6.7e-10, bitscore:
                     29.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTISSEQGSHTAETVAREVQQFLEQRTKQTWDPDTDLFSTGAVSS
                     MFAMELVVHLESSFDVVISGPDLALDNFRTVNAMTAMVLRLRGVKP"
     aSDomain        complement(16443..16649)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_gdmJ_PP-binding.1"
                     /evalue="2.80E-09"
                     /label="gdmJ_PP-binding.1"
                     /locus_tag="gdmJ"
                     /protein_end="83"
                     /protein_start="14"
                     /score="29.3"
                     /tool="antismash"
                     /translation="VAREVQQFLEQRTKQTWDPDTDLFSTGAVSSMFAMELVVHLESSF
                     DVVISGPDLALDNFRTVNAMTAMV"
     gene            complement(16688..17554)
                     /gene="gdmK"
     CDS             complement(16688..17554)
                     /codon_start=1
                     /gene="gdmK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095:3-hydroxybutyryl-CoA dehydrogenase (Score: 291.9;
                     E-value: 7.4e-89)"
                     /gene_kind="biosynthetic-additional"
                     /note="methoxymalonyl-ACP biosynthesis pathway protein;
                     fkbK"
                     /product="GdmK"
                     /protein_id="ABI93786.1"
                     /transl_table=11
                     /translation="MSGHAEAHRLMVLGAGTMGLGITSLAVGHGIPVTVVEVDEAKAGR
                     TRAAVTERLRMAQLMRALPADRPPGELTVTASPADGREATAVVEAVTEDTPTKAKVLEA
                     VAGLTGGRVPLISNTSSIPIDELAGFIADPARLVGTHFMNPPYLIPTVEVIRGPRTGEA
                     AMAAVTDLLRALERKPVVVGDGPGFVTSRVLHPMINDAIRVVQEGTATAEAVDVLMRDC
                     LGHRTGPLRTADLIGLDNLADSLRVLHERTGDARCAPSELLLEKVRDGHLGRKSGRGFY
                     AYGKELA"
     gene            17800..18456
                     /gene="gdmG"
     CDS             17800..18456
                     /codon_start=1
                     /gene="gdmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /note="putative O-methyltransferase; fkbG"
                     /product="gdmG"
                     /protein_id="ABI93787.1"
                     /sec_met_domain="Methyltransf_3 (E-value: 2.8e-71,
                     bitscore: 228.8, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQQVDVTEEILGYVRELSLRDDEVLAGLRAETAGLPAAQAMQVM
                     PEEGQLLGLLVRLVGARSVLEIGTFTGYSTLCMARALPADGTLITCDITEKWPGLGRPF
                     WERAEVADRIDVRIGDAKDTLAGLRRAGREFDLVFIDADKTGYAHYYEESLAMLRRGGL
                     IVLDNTLFFGRVTDPAAQDADTAALREMNKLLREDGRVEISMLTVGDGITLAVKR"
     gene            complement(18563..21346)
                     /gene="gdmRII"
     CDS             complement(18563..21346)
                     /codon_start=1
                     /gene="gdmRII"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 1030.7; E-value: 0)"
                     /gene_kind="regulatory"
                     /note="putative transcriptional regulator; hbmRII"
                     /product="GdmRII"
                     /protein_id="ABI93788.1"
                     /transl_table=11
                     /translation="MPFSYAMPVNTERNSHPMDTVLNAAAHLGHAFGDSLVRPGQALLL
                     DGPLACGKTTLLRSFAERAAAAGRLVITATCSPCERDLPFGVVSQLARGARKSAGGPPE
                     VPGLPDILRGTSDPVDRAEIARLCHRLCTLLIDYAEHTPLLLAVDDVRHSDPASAHFLL
                     QLVRRLDSARIAAVFTDDLSLPAPTLPLRYELLRSQRLHRIGLGPLTPDEVADVVVAEL
                     GETASPRAGDVYAATGGNRLLLHTLLADYREHGEARQTGYGQSFLSCLHRNEPIFLDVV
                     RALAVVGFSLPATDLAWLTGHEPEPIGQVLAALTGAGLMDEGAFRQEAARLSVLNDTPA
                     LTRRTLHQRAARLLHDQGRPATTIARHLVRAGRIPDSWSPELLLEVAEQVAVGEEASVA
                     VDLLEQSLEQCPHQERRAALQAKLAEAEWKINPSTATRHHTPLYGAVRAGRLGLPDSVT
                     LLMQLLWKGGLTEVEGLLAHLREDPAATDQLHAIEAALTCTYPWLAERRPAPAHHGGSA
                     ATRAAVWPRAGTVLADVLTGGQTHDTVRRAEEVLRELQLGHDPACQEQAGLFALLALVY
                     GGRIDLASAWCEGALGETGAGPHVPMRQAVLAAARSEIALRRGDLAEAAERSRAALTHA
                     SPGAWGVAVGLPLGSLILACTRMGRHEEAGFHVAQTVPNAMFKSSYGLHYLYARGHYFL
                     AAGRHQAALADFLLCGELLTDWGLSSGCDPVPWRIGAAEAWLAQGNHDQARILVYQQLS
                     RPHTDGARARGQSLRLLAATSSAKRRPQLLNEAVGLFTEQEDKYELARTLWDLSQAYHA
                     LGEKKQARRTMRRAWHVAKMCDAASLYEEWLPADDQSQAVAPAPKADAGIERLTHSERR
                     VASLAAMGYTNREIAGKLYVTASTVEQHLTRVFRKLDIKHREQLPTELYADRMELA"
     misc_feature    complement(20141..20143)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(21660..22724)
                     /gene="gdmO"
     CDS             complement(21660..22724)
                     /codon_start=1
                     /gene="gdmO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 366.1; E-value:
                     2.7e-111)"
                     /gene_kind="biosynthetic"
                     /note="putative aminoDHQ synthase; hbmO"
                     /product="GdmO"
                     /protein_id="ABI93789.1"
                     /sec_met_domain="DHQ_synthase (E-value: 2e-82, bitscore:
                     266.0, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTSSPAASSAAPFRQVTVALAERSYTVHIGHGVRRLLPRVVS
                     ALGARKAVVVTARPPEQTPDPKVPSLVVSTRDGEEAKDLAAVTDLCRRFVEFGLTRSDV
                     VVSCGGGTTTDTVGLAAALYHRGTPVVHVPTSLLAQVDASVGGKTAVNLPEGKNLVGAY
                     WQPAAVLCDLDHLTTLPEREWRNGLGEIARCHFIGAPDLDGLPLLDQIAASVTLKAGIV
                     AADERDAGLRHILNYGHTLGHALERATGFALRHGEGVAIGTVFAGRLAGALGRIGPERV
                     AEHHDVVARYGLPTALPAQVPVAELVELMRLDKKATDGLTFVLDGPDGPGLVPGIPEDT
                     VSATLAAMPREPAG"
     gene            complement(23055..24257)
                     /gene="gdmP"
     CDS             complement(23055..24257)
                     /codon_start=1
                     /gene="gdmP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 446.8; E-value:
                     1.1e-135)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450; PikC subfamily; hbmP"
                     /product="GdmP"
                     /protein_id="ABI93790.1"
                     /sec_met_domain="p450 (E-value: 9.1e-24, bitscore: 73.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRTDEIRGYPELRAAACPFSPPPGYEELRERSAVTRVRMWDGST
                     PFLVTGYHEARAVLGDSRFSADGTHKGMPRFTKFEVPAEVFNLGRMDDPEHARIRRMLT
                     AHSTIRRTEAMRPMIQGIVDGLLDRLIAEGPPADLVADFAFPLPSQVIAVMLGVSDADF
                     AEFQRASQGVMDFTVSTEEMGAALGVMVDYVSRMCAAKRAAPGDDLLSRLIVDQELTGG
                     LTQQQVVATALVLLLAGHETTANMIALSGVLLLRHPEQLARLRADPGLMPNAVDELLRY
                     ITIVQEGTGRVAAEDVEVGGVLIPAGEGVIINLPSANRDPHFADAHELDLGRPNAREHI
                     GFGFGVHQCLGQTLARVELQIALETLLRRLPALRLEVPLDDLAFLYESMNFGVARVPVA
                     W"
     gene            complement(24390..27296)
                     /allele="hbmRI"
                     /gene="gdmRI"
     CDS             complement(24390..27296)
                     /allele="hbmRI"
                     /codon_start=1
                     /gene="gdmRI"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 707.7; E-value:
                     4.5e-214)"
                     /gene_kind="regulatory"
                     /note="putative transcriptional regulator"
                     /product="GdmRI"
                     /protein_id="ABI93791.1"
                     /transl_table=11
                     /translation="MTAEINSSLRRNPPQRGLMSMGLTDYQSRLRDVLGTAARGNGGLL
                     QVVGGPGVGKATLLSSLEEQAAESDAVCLTASGFAEDTAIPFNIVEQLIRSSAAMGELD
                     VVARWRTAGERYSEAEHGMLAMLVREISDVLHRIAGGKQLVIAVDDVEHVDYPSLMCLL
                     HIARHASGTRTLVAMSSGRTHHLCARVQGFHNLYKVEIGTLSESGVVRLLERHADADLA
                     DRIGASCHAISGGNPRLVRALLHDHLMSAPDGSEREVTVGAEFRDSYRWSLLCHPSLLQ
                     MAQILAVLGPYGSPRRVAGLLECGEERAARAIDVLDSAGLLEDGCFRHPAARSVALETL
                     AVEERARLGAKAAELLYADGADPIAVAELLVTAGKTPDHKGVAVLWHAAQKNLDEGRTE
                     EAVAGLRLAARADLGRRERLDIRMALVGALWAGNPAAAEPELDRLMAAIRTESPADIPE
                     QYLCFLLFMVLWFGRFSDVEEAFTWLSGSGGSGNASSMAALRVTRQWVTFLKPTLIHHF
                     PDQDPSDREVDGLWAANLEHGLQLSVDELGMEIGHLQDPRQMADFSPDTMHLLSHSNHF
                     WFAYAYACRIVWALAARGETEAADRLCGALFTAADKLNMKTPCAVALSMRAYIQCRQGD
                     FTSAIDLAGTALRSIPPRGWGVAIGLPLSVLVAAHTAIGRLDEAQRYLRYWVPKEMFDS
                     VVGLEYLRARGQYCLATNRPYAALNDFMVSGMLIDQWPVDFGDLAPWRIDAAEAYLHVH
                     EPVEAKRLALEELKLSPDRPMSTRGRALRVLAMAEDPDKRRLLLYQSVKCLREHGDRYG
                     LARTLVELSRDFLSTGETQQARATWHEAQKLMDECGMSAQHESRRDPVMGGAESPADPQ
                     PPGNSEDSGEPGVPEDTALGTSAEDAEPPVLSEAEWRVATLAASRMTNRQIAKSLYITV
                     STVEQHLTRVYRKLSVGNRQDLSRRLWPLIGATGSSSC"
     misc_feature    complement(25314..25316)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(26010..26012)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(26475..26477)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(27123..27125)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ggatcccgag gagctgtgct ccccggagta ctgggtgcgg catgtgcgtg gcgcggtgcg
       61 gttcctcgac ggtgtccgca ccctggccga cgagggcgtg cgcacccatc tggagctcgg
      121 cccggacggc gtgctgaccg cgatgggcca ggactgtctg ccggatgcgg gcgcggaggc
      181 ggataccgcg ttcgcggcgt tcgtgccgtc cctgcgtccg ggcgtccagg aggcccacgc
      241 gacgctggcc gggctcgcgg gtctgtacgt ccggggtgtg ccggtggact gggacgcgat
      301 gttcgccggg tccggcgccc ggcgcgtcga ccttccgacg tacgccttcc agcatgagca
      361 ctactggctg gagcggcccg ccgggtccgg cgacgtgggc gctgtggggc tcggcgcggc
      421 gggccatcca ctgctgggcg cggtggtgca actgccggag acgggcggtg tgcagctcag
      481 cgggcggctg tcggtgcggg cccagccctg gctgggcgaa cacatcatct ccggcactgt
      541 actggtgccc ggcacggcca tggtggagct ggcggtccgc gccggggacg agaccggcac
      601 cccggtgctg gaggagctgg tgatcggtca gccgatgctc ctgcccggcg acaccgcgct
      661 gagcgtgcag gtcgtggtgg gcacggacga gggcgggcgg cgcacggtgc ggatctactc
      721 ccgcgccgac ggggccacgg actggaccga gcacgccacc ggcacgctca tggcgcaggg
      781 cccggcaccg ctggacgggg ccaccggcga gtggccgccc gcggaggccg agccgatccc
      841 ggtggaggac ttctaccgtt cgctcgtgga cgccggctat gcgtacggac cggcgttccg
      901 cgggctcgcc gccgcgtggc gcctggacgg tgaggtcttc ggcgaggtgg cgctgccgga
      961 gacgtacgcc gaggaggccg aacggttcgg catccacccg gcgttgctgg acgccgcgct
     1021 gcacgcgggc aacttctgcc tgccctccga cccggcgcgg caggtgaccc tgctgccgtt
     1081 cgcctggaac aacgtacgtc tgtacgcggg cggcgcgtcc gcggtccggg tgcaggtccg
     1141 cccggccggt gacgatgcct tctcggtacg tctgaccgat ggctcgggcc ggacggtggc
     1201 ctccgtggag gcgctgaccc tgcgcgcggt ggacccggcc cagctggaga cgaacacggc
     1261 cgacgacgcg ctgtggacgg tccggtggag cgaacacccc ctgccggacg gcacggtctc
     1321 ctgggccccg ctcggcgagg cggcggcagg aagcgatacg gccaccgaag gcaccctccc
     1381 cgacgtcctc gtggccgaca cgcgcacatg ggccgaagac ctcaccgagc cgctgcccgc
     1441 gcgggcccgg gagctgaccg gccgcctgct ggaggagatc cagcggtggg tcaccgacga
     1501 cgccatggcc gggacgcggc tggccgtggt cacccgcggc gcggtcgccg tgcacggcga
     1561 cgccgaggtc accgacccgg ccgccgccgc ggtctggggt ctggtccgct cggcccaggc
     1621 cgaacacccg gggcggctgg ccctggtgga cgccgacggc gcgtgcgagg agttgcccgc
     1681 gggtgtgtgg tccggggacg agccccaact ggcggtgcgc ggtggcaccg tatgggtgcc
     1741 acgcctggcc cgggtggagc cgggcctgcg tgtgcccgag cagcggtcgt ggcatctgga
     1801 ctcggccgaa tacggcacgc tggacaatct ggcgctgttg cccgacgagg cccggaccgc
     1861 accgctggag gccggtcagg tgcggatcga ggtccgcgcc gccgggctca acttccgcga
     1921 tgtcctggtg gccctcggta tgtatccggg ccggtcggtg atcggcacgg agggggccgg
     1981 tgtggtgacc gaggtcggcc cggacgtggc ggacctggcc gtgggcgacc gggtgatggg
     2041 cctgttctcc ggctcgttcg gcccgctggc caccgccgac gcgcgcacgg tgatccggat
     2101 gccggagggc tggtcgttcg gcacggcggc cggagtgccg gtggcgtatc tgacggcgct
     2161 gtacgcgttg caggacctcg ggaaggtgcg gccgggcgag acggtgctgg tgcacgccgc
     2221 agcgggcggt gtgggcatgg ccgccgtcca gctcgcacag cacctcggcg ccaccgtcct
     2281 gggcaccgcc cacccctcca aacaccacgc cctccaccgg ctcggcgtgc ccgccgaacg
     2341 gctcgcctcc agccgcgacc tcggctacgc cggcaccttc cccaccgccg acgtcgtcct
     2401 caactccctc accggcgaac acatcgacgc ctccctcggc cttctcggcc ccggcggccg
     2461 gttcctggag atgggaaaga ccgacctgcg ggagcccggc gaggtcgggg cgcgccatcc
     2521 cgaggtcacc taccgggcgt tcgacctcgg tggtgaggcc cccgcggacc gggtgcggga
     2581 gttgctgcgc cagctggtgg aactgttcga ggcgggccgg atcgagccgc tgccggtacg
     2641 gcactgggac atcacccgag ccccggaggc gttccgctgg atgagccagg gccgtcacac
     2701 cggcaagatc gtgctcacca tcccccgcac cctcgacccc gacggcaccg tcctggtcac
     2761 cggcggcacc ggcaccctcg gcgccaccat cgcccgccac ctcatcaccc accacggcgc
     2821 acgccacctg ctcctcgtca gccgccaagg ccccgacgcc cccggcgcga ccgaactcgc
     2881 cacagaactc tccgaactcg gtgccaccgt ccacatcacc gcctgcgaca ccgccgaccg
     2941 ccaccacctc accaccaccc tcgccaacat cccacccgac catccactga cagccgtcat
     3001 ccacaccgcc ggaaccctcg acgacggcat cctgaccgcc ctcacccccc tacgactcga
     3061 caccgtcttc cgccccaaaa tcgacgcggt cacccacctc cacgacctca cccgcgatca
     3121 ggacttggcg gcgttcgtgg tgtactcgtc ggccgccgga gtgctcggcg ggcccggcca
     3181 gggcaactac tcggccgcca acgcctatct ggacggcctc gcgcagtggc ggcgtgcgcg
     3241 tgggcttccc gccacctcgc tggcgtgggg catgtgggca gagacaagcg gtatgacggc
     3301 cgggctgggc tccggcgatc tgcaccgggt gcgccgcggt ggcatcgtcg ggctgtccac
     3361 ggcggaggcg ctggacctgt tcgaccggtc ggtggcgtcg gggctgtcgc tgctgatgcc
     3421 attgcggttc gacttcgccg cactcggcgc ggaggccacg gagccaccgc cgctgctgcg
     3481 cggtctggtc cggcccgccc ggcgtacggc ccggccggtg ccgaaggccg ctgagggcgg
     3541 gctcgtacag cgactggccg ggttggccac ggccgaacag cagcggctgc tcgtcgagtt
     3601 gacccgcgaa gagaccgctt cggttctcgg gttccccacc gtcgacccca taggtccgga
     3661 acaggcgttc cgggacctgg gaatcgactc gctgaccgcg gtggagctcc gcaaccgcct
     3721 caacacggcc accgggctac ggctgcccgc gacgctggtc ttcgaccacc cgacgcctca
     3781 ggccaccgcc gagttcctgc gcgaccagct gggcgggcgg accgtggagg ccgcgccccg
     3841 gccgacccac cgccgccggt ccgctccgga cgaagccgag gatccggtcg tcgtggtggg
     3901 catgggctgc cggctgcccg gcgacgtccg cacccccgag gacctgtggc ggctggtggc
     3961 cgccggaacc gacgcgatcg gcccgttccc gcaggaccgg gggtgggacc tggccgggct
     4021 gttcgacccc gacccggacg ccgtgggcaa gtcctacgta cgcgagggcg gattcctcac
     4081 cgacgcgggt ggattcgacg ccgccttctt cggcatctcc ccgcgcgagg ccctgtcgat
     4141 ggacccgcag cagcgcgtat tgctggagac cgcctgggag accctggaag gctccgggat
     4201 tgttcccacg tcactgcgcg gccaggaggt cggcgtcttc gtcggcgcca gcggccaggg
     4261 gtacggcacc ggccccggcg cggcgccgga aggcttggag ggctacctcg gggtgggcgg
     4321 cgcgacgagc gtggcgtcgg gccgggtgtc gtacaccttc ggcctgaccg gtcccgcggt
     4381 gacggtggac acggcgtgct cctcctcgct ggtggccatc cacctcgccg tacaagccct
     4441 gcgctccggc gagtgcacga tggcactcgc cgggggcgtc gccgtcatgg gccagcccgg
     4501 cgccttcgtg gagttctccc gccagcgcgg tctggcgtcc gacggccgct gcaagtcctt
     4561 cggcgagggc gccgacggca ccaactggtc cgagggcgta gggctcttgc tgctggaacg
     4621 gctgtccgac gcccgccgcg acggccacga ggtactggcc gtgatccgtg gcacggcggt
     4681 caaccaggac ggcgcaagca acggcctcac cgcgcccaac ggcccctccc agcaacgggt
     4741 gatccggcag gcactggcca acgccgggct gacagcggcc gatgtggacg ccgtcgaggc
     4801 ccatggcacc ggcaccgcac tcggcgaccc catcgaggcc caggcactcc tggccaccta
     4861 cggccaggag cgacagggtg acgagccgct gtggctcgga tcgctgaagt ccaacatcgg
     4921 ccacacccaa gcggccgcgg gcgtgtccag cgtcatcaag atggtgctgg cgctgcggca
     4981 cagcacgctt ccgcgctccc tgcacgccga cgaacccacc gcccaggtgg actggacgtc
     5041 gggcgcggtg tccctgctcg ccgaggcgcg cccctggccg gtgaacggac acccccgccg
     5101 cgccgggatc tcctccttcg gcgtcagtgg gacgaacgca cacgtggtcc tggaacaggc
     5161 accgaacccc gagcccgcgc cgaaggtgga cgacggtacg gagatccccg gtctggtcgc
     5221 caccggcgga atcgccccct gggtgctgtc ggccaagacc gccacagccc tgcgagctca
     5281 ggcccaatgc ctcctggacc acctggaatc cggcgccgac gcacaccccg tggacatcgg
     5341 ctggtccctg gccaccaccc gcaccctcca cgaccaccgc gccgtcatcc tcgccgacac
     5401 caccgccgaa agcactgaga ccacggccgc cctcaccgcc ctcgcgagcg ggcagccgca
     5461 cccccgcctc accaccggcc acgccaccac ccacggcaaa accgccttcg tcttccccgg
     5521 ccaaggcgcc caatgggtcg gaatgggagc ccaactcctc accacttccc ccgtcttcgc
     5581 cgaacgcctc cacgaatgcg ccgcggccct ggccccgtac accgactgga acctcatcga
     5641 cgtcatcacc ggcgcacccg acgcgccctc gctcgaccgt gtcgatgtcg tacaacccgc
     5701 caccttcgct gtggtcgtct ccctggccgc actgtggcag tcctgcggca tccaccccga
     5761 cgccgtcatc ggccactccc agggcgaaat cgccgccgcc tgcgtcgccg gacatctcac
     5821 cctccccacc gccgccaaaa tcatcaccct ccgcagccaa accatcgccc accatctggc
     5881 cggacacggc ggcatgatgt cgctcgccgc ccccgccgac accatcgacc tcaccaactg
     5941 gcacggcaaa ctctggatcg ccgcacacaa cggccccaac gccaccgtca tcgcaggcga
     6001 caccgacgcc ctccatgagc ttcacgctca ctacaccgac cagggcatca gggcccgcat
     6061 catccccgtc gactacgcct cccacaccgg acacgtcgac accatcgagg acgaactcca
     6121 ccaggctctg gccgacacca ccaccgagcc cggcaccatc ccctggctct ccaccgtcac
     6181 cggccagtgg atcgaaccca ataccgccga cggcgactac tggttccgca acctgcgcca
     6241 gaccgtgcgg ttcgacgcca ccgtccgcac cctcgccgac gacggctacc gcaccttcat
     6301 cgaagtcagc ccccaccccg tcctcaccac cgccatccaa gaaaccctcg aagcaaacca
     6361 aaccccccac accaccatca ccggcaccct ccgccgcaac gacgacaccc ccacccgatt
     6421 cctcacccac ctcgcagaac tgtccaccag gggaacacca atggactggc ccaccgcgta
     6481 caccggatca caaccctccc aaatcccgct gcccacctac cccttccaac acgagacgtt
     6541 ctggctggac cgtggcggtc cgggcgatgt ccgtgccgtg ggtctcgagg acaccggcca
     6601 cccgctggtc ggggccgtgg tgagcgtgcc cgacaccgga ggtgtgctgc tcaccgggcg
     6661 tctctccctg cccacccacc cctggctggc cgaccacgcg gtctccggca ccgtgctgct
     6721 cccgggtacg gcgatggtcg agctggcggt gcgtgccggg gacgaggcgg acacccccgt
     6781 actggaggag ctggtcatca gccggccgat gacggtgccg gacgagggca ccctgcatgt
     6841 ccaggtgctc gtcggcggag aggagcgcgg gcgccgcaag gtgggggtct actcccgccc
     6901 ggagggcata cgggagtgga ccgagcacgc caccggcacg ctgaccgcgg gggccgccgt
     6961 cccgccggaa gaggccgagg ccgcgctgcc gtggccgccc gagggtgcgg agcccgtggc
     7021 cctggagggg ttctacgagc acctggccga ggtcgggtac gagtacggcc cggcgttccg
     7081 tggcctgagg gcggtgtgga agcgggacga cgaggtgttc gccgaggtgt cggtgccgga
     7141 ggagcagacc ggggtggccg ggcggttcgg catccatccg gcgctgctgg acgccactct
     7201 gcacgccggg aacttctgct tccagtccgc tggtgagcgg cccacgatgc tgccgttcgc
     7261 gtggaccgac gtacggctcc acgccgtggg cgccaccgcg gtgcgggtgc gcgcgacggt
     7321 gtccggcggg gacgggttgt gtgtgcggat caccgatccg cggggtgtgc cggtcgccac
     7381 gatcggctcc ctccagctcc gggagaccac acccgaccag ctgcgcgcgc tggccgccgc
     7441 gtcgggcggc aatgccctgt gggcggtcga atgggccgaa tgcgggctcg gcgccaccga
     7501 agcgcgctgg gccacggtcg gggagagcgg gctcccggac gccccgtcga gctatgccga
     7561 tgtcccggag gtcgcggagg ccggggagcg gcccgaggtg ctcgtcgccg acgtgtccgc
     7621 ctgggtcccc gaacagaccg ggcccatcga ccgtacgcac gcgctctgcg cccgggtgct
     7681 ggatctgctg cgggagtggg tggaccggcc cgaactggcg gacacccgcc tggccgtcct
     7741 gacccgcggc gccatggccg tccacgacac cgccgaggtc accgacccgg ccgcggccgc
     7801 ggtctggggt ctggtccgct ccgcccagtc cgagcacccc ggccgggtcc ggctcatcga
     7861 cgtcgacggc cactcccacc agaccctgcc cacagcgctc accacggccg aagcccaact
     7921 cgcccttcgc gacaccaccg cctacacgcc ccatctgacc gccgcgccca ccggcacacc
     7981 gtcccagccc ctcgccctgg ccccggaagg gaccgttctc atcaccggtg gcaccggcac
     8041 cctcggcgcc ctcaccgccc gccacctcat cacccagcac ggcgcgcgcg acctcctcct
     8101 ggtcagccgc caggggcccg atgcccccgg cgcggcccgg ctcggcgagg agctgacgcg
     8161 gctcggcgcc cgtatccaca tcgccgcctg cgacaccgcc gaccgcgacc aactcgccgc
     8221 cgtccttgac ggcatccccg ccgaccatcc actgaccgcc gtggtccaca ccgcggggac
     8281 cctggacgac gccctgctca ccgatctcac cccgcggcgc ctcgacaccg ttctgcgccc
     8341 caaggtcgac gccctcaccc atctccacga cctcacccgc gatctcgacc tcgcggcctt
     8401 cgtcgtcttc tcctccgcca ccggcgtcct cggcaccccc ggccaggcca actacgccgc
     8461 cgccaacacc tacgccgacg cgctcgccca gcagcgccac gccgccgggc tccccgccac
     8521 ctcactcgcc tggggcctgt gggagaccac cagcgccctc acggccggta tgaccaccgc
     8581 ccagcagcaa cggacccggc acagcggtgt catccccctg accgacgccg acggtatgcg
     8641 cctcctggac accgcgctca ccaccccgca cccccatctc atccccctcg agctggacct
     8701 cgcggccctc cggaacaaca ccgaccccca cacactcccg cccctcctgc gcggcctcat
     8761 ccgcggccac caccgcccca ccgcccacgc ctcggcccgg cccgacgccg ccccgtccct
     8821 cgcccaagag ctggccgcgc tcgacccggc ccagcggcac cagcgcctga ccgaactggt
     8881 ccgcgccgag gccgcggccg tcctcggaca ccccaccccg gacgcggtgg gcccgaacga
     8941 cccgctgttc gagatcgggt tcgactcgct gaccgcggtg gaactgcgca accgcctcaa
     9001 cgcggccacc ggcctccagc tcgcggcggc gatgctgttc gactacccca ccccgtcgat
     9061 ggccgccgag cacctccagg agcagctcgc gctggatgcc acgaacgcac ccgtggcggc
     9121 ccgagaagcg gcggaagacg acgaccagaa cacggagagg tgaagacgag catgttcgac
     9181 gtggcgaagt acctgcggcg catcggggtg gagtccatac ccgcaccaac tctggacacc
     9241 ctccggcacc tgcacaaacg gcatctcatg gcggtcccgt acgacaactc gacggccccc
     9301 gaccggctcc cggcctcgcg gcatctgacg aacgtcccgc tggacctggt gttcgagcat
     9361 gtggtgaccg agggccatgg cggagtgtgc tacgagctca accggctgtt ccacacgctg
     9421 ctggccgaac tcggctacga cgtgcgcatg gtggcggcgg cggtacggca ggcgaacggg
     9481 gccttcggcc cggagcgcga gcacaccttc gacctggtcc gcctcgacgg gcggacccac
     9541 ctggtggacg tcggtttccc cgggccgtcc tattcggagc cgctgcgcct gtccgaggag
     9601 gagcagcacc agtacggctg tgcctaccgc gtgaccgaac acgacggcta ccgggtggtg
     9661 gaacggcggc ccaaggagag cggctggcag ccggtgtacc ggttccggcc ggagctggcc
     9721 gacccgtccg gctgggacgc ggtgcggctg gacagcctgg acgactacgc acaggactcg
     9781 gtgctcgccg ggaccacctt ccgcagccgg gccacggaca acggaaagat cgtgctgatc
     9841 ggcaggcgct gcttcaccgt cgaggacggg gtggagcgca ccaaggtgct ggtgaaggcg
     9901 gacgagttcc aggacacggt cgatctgatc ctggcgggcg aatgagcggg aaggagacgg
     9961 cggtggacgt cgcgcgggac acggacaacg gcgggcccaa gaccgatgtg ctgatcgtcg
    10021 ggtacggacc ggtggggcag ctgctgtcgg tgctgctggc ccagcgcggc cgccgggtga
    10081 cggtggtgga gcgctggccg gagccgtacc ggcacccccg ggcggtcggg ttcgacagtg
    10141 aggccgcgcg catcctggcc tcggccggga tcggcgactc gctcgagaag ttcaccgaac
    10201 ccgcgcggga ccacgcctgg cagaacacca agggcgagac gctgatcgac cacgaggtcg
    10261 ccaaccgggg gcactgcacc tggccggagg cgctgtcggc ctatcagccg gccctggagt
    10321 ccgcactgat cgaacacggg gcgacgctgc cgcggctgcg ggtgctgcgc ggctacgagg
    10381 cggtgggact cgcggacaac ggtgaccggg tgaccttgac cgtggtcggt ccggacggcg
    10441 agaggacgga cctcatcgct tcgtgggtgg tcggctgcga cggcgccaac agcctggtgc
    10501 gggcgagtgt cggcaccacg gtgacggacc tcgacttctc ctacgactgg ctgatctgcg
    10561 atgtgcggct gcatgagcac cgcgagttcc ggccgaacaa tctggagatc tgcgatccgg
    10621 cccgcccgcg gaccgcggtg tccgcggggc ccggacaccg gcggtacgag ttcatgcggg
    10681 tgcccgcgga cgaccccgcg cacttcggca ccgtggagag cgcgtgggag ctgctgcggc
    10741 tgttcgacgt gacgcccgac aacggcgtcc tggaccggca tgcggtctac accttccagg
    10801 cccgctgggc ggagcactgg cgggccggac ggctgctgct ggccggggac tcggcgcacc
    10861 tcatgccgcc gttcgcgggg cagggcatgt gctccggatt ccgtgacgcg gcgaatctgg
    10921 cctggaagct ggacctggtg ctgagcgggc acgcggcacc ggcgctgctg gacacctaca
    10981 ccagcgagcg gcgggcgcat gtgcggcacg cggtggagat gtccgtgggc ctgggccggg
    11041 tggtgtgcat ggcggacccg gccgcggcgg cggaccggga cgcggcgatg ctggccgcgc
    11101 ggaagcggaa catcgggccg agcgccgcgc gccgctcggt ggtgcgcccg ctcgtggacg
    11161 ggttgctgcg gcgggacggg cagggccggc cggcgccgta cgccggacag gcggccccac
    11221 agtggcgggt gggccgcgcg ggcggcaccg ggctgttcga cgatgtggtg ggcaccggtt
    11281 tcatcctgct gtacggcgag gacgtggtcc cggcgctgga cgcgcggcag ctgacgttcc
    11341 tcgacaacat cggggcccgg ctggtgcgtg tggtgcgcgc ggaaacgccc gcggccgacc
    11401 tggaaccagg ggacgcgcgg gacgtggagg gccggtatct gccgtatctg tcggagatgg
    11461 gcgcgctggc ggtgctggta cgcccggact tctacgtgtt cggcatcgcg ggcgacaagg
    11521 ccgaactgcc ctcgctggtg gacgacttgg cggaacaact caccccgacc gccgccccgt
    11581 cctgaggcac tcccccaccc gaacacgaac tggtcccctt ccccgagtgc cgtgggggga
    11641 aggggaccag ttggtgcgcc cctgtcgatg tgcggttccg ccgcgtgggc gcgaccggcc
    11701 acgacggcgc cgcggccgat cgacggcgga cggaagacgg aagacggaag acggaagacg
    11761 gcgccccagc ggagcgatca cgtatcggag gtcacgctct ccccggtacg cgccgcgaga
    11821 cgccgctcat cgcccgcctt gaccagggcg tatctgatcg ccagcgccgc cgcgttgacc
    11881 gcgtgcagcg cctcctgggc gccggtgtcc gcccgctcct gcccggtggc ggcggccgag
    11941 gtgcactgtg cggcctccag acaggcgacg cacgcctcca cgagggcgtc cggccgcccg
    12001 ccaccggccc ggctcagctt cgccagcagc cgggtgatct cccggtgcac ttcggtgatc
    12061 gggtccgcca ccatcgggtc agcgcccccg cgcgccgtcg tccgcgggcc cctgggccgg
    12121 ctggagctcc ccggccggga cgagggtgag gaaccgctgc tcccacaggg cgaacacctc
    12181 ggcggccagc gcctccgaca gcccgcccac ggccttggcc agatccccga gggtggtggt
    12241 gccgtccacc gcgccgagca gttcgtacag ctcgggcgac accttcgcgg acgggccgcc
    12301 gtcgtagtcg aggtggatct cgtggacctt cgtgcccgcc gaggcgtcgg gaccgctggt
    12361 cctgtgctcg accagccggg tgaccgggcg gaaccgcggc accagaacgc ccaggtcggg
    12421 cgagggcttg gcacgcacca ggcagtcctc caccaccagg gcgtccaggt cggtggtcag
    12481 gaagctggtc accacgtcgt cgaggctctg cacgatgggt tcggcgttgt tgttgaagga
    12541 ggtgttgagc agcacggggg tgccggtcag ctcgccgaac cggcgtacca gccgatggaa
    12601 gcgctcgccc gaggcggccg agacgacctg cacccgggcg gtgccgtcca cgtgggtgac
    12661 cgcgccgagt tcggtacgcc gctccggcag caccggcacc acgaaggaca tgaactcgtg
    12721 gttgccctcc gcgccggaga ggtcgaagta gtcgcgggcg gcttcggcgg tgaccaccgg
    12781 tgcgaacggc cggaagccct cgcgcttctt caccatcgcg ttgatacggg tccggttctc
    12841 ctcggggcgt gcgtccgcga cgatgctgcg gtggcccagg gcgcgggggc cgaactcgga
    12901 ccggccgtac gcccagccga gcacctcgcc ctcggcgagc agtccggccg ccctctccac
    12961 ggcgtctccg gggaactcca catcgatcag cggcgcccag tcggccagcc gtgccctgat
    13021 ccgctcccgg gtgcccagcg ccgggccgag actcgcgctg agcagccgct tccggggccg
    13081 ttggagagtg cccaggctcg ccgcggcggc gtaggcggcg ccctcgcccg cgcccgcgtc
    13141 gtgcgaggcg gggtggatga acacctcgtc gaagaggccg gacttgagga tcaggccgtt
    13201 gaggctggag ttgtgggcga cgccgccgcc gaagcagagg cgggacagcc cgctggtctt
    13261 cgcccagtgc tggaggatgt gcagcacgat cttctcgacc gcctcctgga gcgcggcggc
    13321 gaagtcgcgg tgtgcttggg tgaacggctc gctcttgcgg cgcggccgga agccctcggc
    13381 gtagaacagc gggctgacca ggttcggcac catgatgttg ccgtgcagtt cgtactcgcc
    13441 gttgtcctgg agggtgtaga gcttggagaa ggtgtcgcgg taggtcgcgg ggtcgcccca
    13501 gggggccagg cccatcacct tgtactcgtc gccgaagccg tagccgagca gataggtggc
    13561 gttcagatag agcccgccca gtgacttggg caccgggtag tcggccagcc tctccaggtg
    13621 ggtgccctcg gcgcggtaga cggtgccgga gtgcagttcg ccccggccgt ccagcaccag
    13681 gaccagcgcc gagtccatgc cggagtgcag atatgtggag tacgcgtgtg cctcgtggtg
    13741 cggcacatag acgagcttgt cctccggcag gtcccagtcc aggccctcct tcagccgctc
    13801 ccggatcagc tcccgggagt agcgcagggg cacccgcgga tattcggtgt agaggtggtt
    13861 gaggacggtg tcgatgtggt tctcgggaaa gtagtagccc accgcgtcga cgtcctcggg
    13921 ccgcgcgccg gccagggcca ggcactcacg gaccgcgttg atggggaatt tggtggtctt
    13981 cttgatccgg ttgagccgct cctcctccac cgcggccacg agttccccgt cgcggatcag
    14041 ggaggccgcc gagtcgtgga agaagacctc gctcagccgc ggcaccacat cggtgtccgc
    14101 ggcggagaag ttgccgttga gcccgagcac aagcacagtg atcacccaaa ccagtcggag
    14161 gcgaacgcga ggatgcgggg cgggagtcgc ccgccggtca ccgggagcgc ggcagcgccg
    14221 cgtcggcgag ctcaggcgcg gtcagccgca gcgtggtcgg ggccggctgg aacgcggggg
    14281 tgaggtggag gcgttcgacg ccctcctcgc cgggggccgc gagggcggcg gtgcaggcgc
    14341 agtcggcgtc ggcgaacccg gcgaagcggt aggcgacctc catcatccgg ttgcggtcgg
    14401 tgcgccggaa gtcggcggcc agatgcaccc cggcacgcgc cgcctggtcg gccagccagt
    14461 tcagcagggt ggacccggcg ccgtaggaga ccacacggca ggaggtggcg agcagtttca
    14521 gatgccacac cgccgggtgg cgttccagca gcacgatgcc gacggcgccg tgcgggccga
    14581 accggtcggc catcgtgatg accagcacct cgtgcgcggg gtcggtgagc agtccgcgca
    14641 gtacggagtc ggagtagtgc acaccggtgg cgttcatctg gctggtgcgc agggtcagtt
    14701 cctcgacccg ggacagctcc cgctcggtgg cgcgggagat ggccatctcg atgtccaggg
    14761 tgcgcaggaa ctcctcgtcg ggtccgccga actccgcccg ctcggcgtca cggcggaacc
    14821 ccgactggta catggtgcgc cgctgccgtg agtccacggt gaccacggcg gggctgaact
    14881 cgggcagccc ggtgagtccg gccacgtcct cggcggtgta gcagcgcacc tcggggagcc
    14941 ggtagccgac ctcggcgcgc tcggcgggct ggtcgtccac gaaggccatg gcacggtgtg
    15001 cgaagttcag ccgctccgcg atggcacgca ccgattccga cttgggcccc cagccgatgt
    15061 gcggcagcac gaagtactcg gcgaggccca gcgcctccag gcgcgcccag gcgtggtcgt
    15121 ggtcgttctt gctggcgatc gactggagaa tgccgcggtc gtcgagggtg gtgatgacat
    15181 cgcgcaccca tgcgaacggc ggcacctcgc cgtcctcgag cagggtgccg cgccagagtg
    15241 tgttgtcgag gtcccagacg agacatttga cggccgccgg cggctcgctc acgggcttcc
    15301 cctccgtcat ggtcgcacct tcttccgcat gtgccgggcg agcacgagct ggcagatctc
    15361 gctggtgccc tcgatgactt ccatcagctt cgcgtcgcgg taggcacggg ccaccacatg
    15421 gccgtcggac gccccggccg acgccaggag ctgtacggcg cgtgccgcgc cctgtgccgc
    15481 ctcgcgcgag gcgacgtact tcgcgtgcac cgcgtcgacg gccatgtcgg gcgagccggt
    15541 gtcccaggag gcgctggcgt gttcacaggc ccgggtggcg tgccgctccg cgacgtacag
    15601 ctcggccagg tgccgggcca ccaactggtg ctcggcgagc gcccggccgg actgctcccg
    15661 ggtggcggtg tgcgtggcgg cggcgtccag gcacgcgcgc aggatgccga cgcaccccca
    15721 ggccacggac atgcgcccgt aggtgagcgc ggcggtggtc gccagggaaa gcggcagccc
    15781 ggtgccgccg agtacatgcc cggcgggcac ccggaccgcg tccagggtga tgttcgcatg
    15841 accggcggcg cggcagccca gggggttctc cacccgtgtg atgcgcactc cgggtgtccg
    15901 ggcgggcacg accacggccg tggcgccgcc ccggtacttc ccgaacacca gcagcagatc
    15961 ggcgtagtgg gcggcggtga tccacacctt ccgtccggtg acgaccacct cggcgccgtc
    16021 gtcggcgatc tcggtctcca tcgccgacag gtcgctgccg gcgccgggtt cgctgaatcc
    16081 gaccgccgcc aggtcaccgg aggtcagccg gggcagaaag gtgtcccact gctcggtgcc
    16141 gccgagcctg cgcaccgtcc acgccgccat gccctgcgag gtcatcacgc tgcgcaggga
    16201 gctgcaccgg gcgccgaccc gcgcggtgag ctccccgttg gcatggctgt ccagtccggt
    16261 gccgccgtgc tcggggccga cctgtgcgca cagcacaccg gaggcgccga gtttgaccag
    16321 gaggtcgcgg ggcagttccc cggccaggtc ccaggcgtcg gcccggtccc cgatcaaccc
    16381 gctgaccagc tccgcgtggt cggtggcggc gtcggtcacg gcttgacccc gcgcagccgc
    16441 aggaccatcg cggtcatcgc gttcaccgta cggaagttgt ccagcgccag atcggggccg
    16501 ctgatcacca cgtcgaagga cgactccagg tgcacgacca gttccatggc gaacatcgag
    16561 gacacggcgc cggtgctgaa caggtcggtg tccgggtccc aggtctgctt ggtgcgctgt
    16621 tcgaggaact gctgcacctc ccgcgccacc gtctcggcgg tgtggctgcc ctgctcggat
    16681 gagatggtca cgccagctcc ttcccgtatg cgtagaaccc gcggcccgac ttgcggccca
    16741 gatggccgtc gcggaccttc tccagcagca attcgctcgg tgcgcaccgg gcgtcgccgg
    16801 tgcgttcatg cagcacgcgc agcgagtcgg cgaggttgtc caggccgatc aggtccgcgg
    16861 tgcgcagcgg tccggtgcgg tggcccaggc agtcccgcat gaggacgtcc acggcctccg
    16921 ccgtcgccgt gccctcctgc accacacgga tcgcgtcgtt gatcatcggg tgcagcaccc
    16981 ggctggtgac gaaccccggc ccgtcgccga cgacgaccgg cttgcgctcc agcgcgcgca
    17041 gcagatccgt cacggcggcc atcgccgctt ccccggtacg ggggccgcgg atcacctcca
    17101 ccgtggggat cagatagggc gggttcatga agtgggtgcc gaccagccgt gccggatcgg
    17161 cgatgaaacc ggccagttcg tcgatcggga tggaggaggt gttcgagatc agcggcaccc
    17221 gcccgccggt gagcccggcg accgcttcga gcaccttggc cttggtgggg gtgtcctcgg
    17281 tgacggcctc caccacggcg gtggcctccc ggccgtcggc cggggacgcg gtgaccgtca
    17341 gctcgccggg cggccggtcg gcgggcaggg cccgcatgag ctgggccatg cggagccgtt
    17401 cggtgaccgc ggcccgcgtc cggccggcct tggcctcgtc cacctcgacg accgtcaccg
    17461 ggattccgtg ccccacggcg agagaggtga tccccagtcc cattgttccc gcacccagca
    17521 ccatgagccg gtgcgcttcc gcatgtccgc tcatcaatcg cctccgcagc gcgttgtgaa
    17581 caacgtgccg accatgacac gcgcttgtcg cgttcacgat attctcgggg cggtcacgca
    17641 aatcccctaa ggatcccccc tacacccccc tcagcccgga atatgggttc cggcattccg
    17701 cgggacgcca ttgcgcggca caccggcgga ttcctagcat tggccgcaat gactttcccc
    17761 ggaccttccc tttccacctt tgcggggtgt ggcagtccaa tggctcagca agtcgatgtg
    17821 accgaagaaa ttctcggcta tgtccgggaa ctgtccctgc gcgacgacga ggtcctggcc
    17881 gggctgcggg cggaaaccgc gggtctgccg gccgcacagg ccatgcaggt gatgcccgag
    17941 gagggtcagc tcctcgggct gctggtgcgg ctcgtcggtg cccgttcggt gctggagatc
    18001 ggcaccttca ccggctacag cacactgtgc atggcgcggg ccctgccggc cgacggcacg
    18061 ctgatcacct gcgacatcac ggagaagtgg ccggggctcg ggcgtccgtt ctgggagcgc
    18121 gccgaagtgg cggaccgcat cgatgtgcgc atcggtgacg cgaaggacac actggccgga
    18181 ctgcggcggg cgggccggga gttcgacctg gtcttcatcg acgcggacaa gaccggctac
    18241 gcgcactatt acgaggagtc actggcgatg ctccggcgcg gcggcctcat cgtcctggac
    18301 aacaccctct tcttcggccg ggtgaccgac cccgccgcac aggacgccga caccgccgcc
    18361 ctgcgcgaga tgaacaaact gctccgggag gacggacgcg tcgagatcag catgctcacc
    18421 gtgggcgatg ggatcacgct ggcggtcaaa cgctgagtcc tcgcctgccg tgacggccac
    18481 ttcccgggac ctcccgggaa gtggccgttc gcggtcggtg ctcatgtcgg tgccgggcgg
    18541 agctcccgcc ggggtgccgc cgtcacgcca actccatgcg gtccgcgtag agttcggtgg
    18601 gcagctgctc ccggtgcttg atgtccagct tgcggaagac ccgggtcaga tgctgctcca
    18661 ccgtgctggc cgtgacatac agcttcccgg cgatctcccg gttggtgtag cccatggcgg
    18721 ccagcgacgc gacacgccgt tcggagtgcg tcaaccgctc gatcccggcg tccgccttcg
    18781 gagccggcgc cacggcctgg gactggtcgt cggccggcag ccactcctcg tacagcgacg
    18841 cggcgtcgca catcttcgcc acatgccagg cccggcgcat ggtccggcgg gcctgcttct
    18901 tctcgccgag cgcgtggtac gcctggctga ggtcccacag cgtgcgagcc agctcgtact
    18961 tgtcctcctg ctcggtgaac aggcccaccg cctcgttgag cagctgcggc cgccgcttgg
    19021 ccgagctggt ggcggccagg aggcgcaagg actgcccgcg ggcccgggcg ccgtccgtat
    19081 gcggacggct gagctgctgg tagaccagga tccgggcctg gtcgtggttg ccctgcgcga
    19141 gccatgcctc cgccgcgccg atccgccatg gcaccgggtc gcagccgctg ctcagccccc
    19201 agtcggtgag cagctcgccg cacagcagaa agtccgcgag cgcggcctgg tgccggccgg
    19261 ccgccaggaa gtagtggccg cgcgcgtaca ggtagtgcag cccgtaggag cttttgaaca
    19321 tggcgttggg cacggtctgc gcgacgtgga accccgcctc ctcgtgccgg cccatccgcg
    19381 tacacgccag gatcagggag ccgagcggca gcccgaccgc gacaccccag gcgccgggag
    19441 aggcgtgggt gagggcggcc cgggaccgct ccgcggcctc ggcgaggtca cctcggcgca
    19501 gcgcgatctc cgacctggcc gccgccagca ccgcctgccg catcgggacg tgcggccccg
    19561 cgccggtctc gccgagcgcc ccctcgcacc atgcggacgc caggtcgatc cggccgccgt
    19621 agaccagcgc gagcagggcg aacagcccgg cctgctcctg gcacgccggg tcgtgcccga
    19681 gctggagttc gcgcagcacc tcctcggccc gccggacggt gtcatgggtc tgcccgccgg
    19741 tgagcacgtc cgcgagtacg gtgccggccc gcggccacac cgccgcccgc gtcgcggcgg
    19801 agccaccgtg gtgcgccggg gccggccgcc gctccgcgag ccaggggtag gtgcaggtga
    19861 gcgcggcctc gatggcatgg agctggtcgg tggcggcggg gtcctcgcgc agatgggcga
    19921 gcagcccctc cacctcggtc agcccgccct tccacagcag ctgcatgagc agggtgacgc
    19981 tgtcggggag gccgagccgg ccggcccgga cggcgccgta cagcggtgtg tggtgccggg
    20041 tggcggtgga cgggttgatc ttccattccg cctcggcgag cttcgcctgc aaggcggcgc
    20101 gccgctcctg gtgcggacac tgttcgaggg actgctccag taagtcgacg gcgacggacg
    20161 cctcttcgcc caccgcgacc tgctcggcca cttccagcag cagctccggc gaccatgaat
    20221 cggggatccg cccggcccgc accagatgac gggcgatcgt ggtggcgggc ctgccctggt
    20281 cgtgcagcag ccgcgcggcc cgctggtgca gggtcctgcg ggtcagcgcc ggcgtgtcgt
    20341 tgagcacgct cagccgcgcc gcctcctgcc ggaacgcgcc ctcgtccatc agtccggcgc
    20401 cggtcagcgc cgccagcacc tggccgatgg gctcgggctc gtgtccggtc agccaggcca
    20461 ggtcggtggc gggcaaggag aagcccacca cggccagcgc gcgcaccacg tccaggaaga
    20521 tcggctcatt gcggtgcaga cagctcagga aggactggcc atagccggtc tggcgggcct
    20581 cgccgtgctc gcggtagtcg gccagcaggg tgtgcagcag cagccggttg ccaccggtgg
    20641 cggcgtagac atcgccggcg cgggggctcg cggtctcccc cagctccgcc acgaccacgt
    20701 cggccacctc gtcgggggtg agcgggccga ggccgatccg gtgcaggcgc tgggagcgca
    20761 gcagttcgta gcggagcggc agggtgggcg cgggcaggct cagatcgtcg gtgaacacgg
    20821 cggcgatccg tgccgagtcc agccgccgca ccagttggag gaggaagtgc gcggaggccg
    20881 gatcgctgtg gcgcacatcg tccacggcga gcagcagcgg ggtgtgttcc gcgtagtcga
    20941 tcagcaaggt gcacagccga tggcacagcc gggcgatctc ggcccggtcc accgggtcgc
    21001 tggtcccgcg gaggatgtcc ggcagccccg gcacctcggg cggcccgccc gctgacttcc
    21061 gggcgccgcg ggccagttgg gagacgacac cgaagggaag atcccgctcg cagggagaac
    21121 acgtcgccgt gatgacgagc cggccggccg ccgcggcccg ctcggcgaac gaccggagca
    21181 gggtggtctt accgcatgcc agcggtccgt ccaggagaag agcctgcccg ggccgcacca
    21241 aagagtcacc gaacgcgtgt ccgaggtgcg ccgcggcatt caataccgtg tccatcggat
    21301 gggaattccg ctcggtattc accggcatgg catagctgaa gggcatgttg agggtccccg
    21361 atcgaggtcg acgaaatatg gactcgcgat ccttgaatca gaccgaatat tgatcgggaa
    21421 acgattccat cagtgcgtcc acatcagcat caacccctac cggaacctcc gccccctaac
    21481 ccggtccacc gcatctcgtc cagcacaccg cgctgttcag ttatccggga cgcgcgccgc
    21541 acggtcaacc ccctatcgag gtggcgtgcc cctaaagcga agaggcgatg aatgccgtgg
    21601 cgtatcctcg ttccggccat tccgcttcgt ggcggtcgcc tcttccggag cgcgccgtgt
    21661 caccccgccg gctcgcgggg catcgcggcg agggtggcgc tgacggtgtc ctcggggatc
    21721 ccgggcacca gtccgggccc gtcggggccg tccaggacga acgtcagccc gtcggtggcc
    21781 ttcttgtcca gacgcatcag ctccaccagc tcggccacgg ggacctgggc gggcagcgcg
    21841 gtcggcaggc cgtaacgggc gaccacatca tggtgctcgg ccacccgctc cgggccgata
    21901 cggcccagcg caccggcgag ccggccggcg aagaccgtgc cgatggccac gccctccccg
    21961 tgccgcaggg cgaaccccgt ggcacgttcc agcgcatgcc ccagtgtgtg tccgtagttg
    22021 aggatgtgcc gcaagcccgc gtcgcgttcg tccgcggcga cgatgcccgc cttgagcgtc
    22081 acactggccg cgatctggtc gagcagcggc agcccgtcga gatcgggcgc gccgatgaag
    22141 tggcagcggg cgatctcacc gaggccgttg cgccactccc gttcgggcag ggtggtgagg
    22201 tgatcgaggt cgcagagcac ggccgcgggc tgccagtagg cgccgaccag gttcttgccc
    22261 tcgggcagat tcaccgccgt cttcccgccg acgctcgcgt ccacctgggc cagcagcgag
    22321 gtcggcacat ggacgaccgg tgtgccccgg tggtagaggg cggcggccag gcccaccgtg
    22381 tcggtcgtgg tgccgccgcc acaggacacc accacatccg agcgggtcag cccgaattcg
    22441 acgaaccggc ggcacaggtc cgtcacggcg gccaggtcct tggcctcctc cccgtcgcgc
    22501 gtggacacga cgagcgaggg cactttgggg tcgggcgtct gctccggggg ccgcgcggtg
    22561 accaccaccg ccttgcgcgc gcccagggcg gacaccaccc tcgggagcag ccgccgcaca
    22621 ccgtgtccga tgtggacggt gtacgagcgc tcggccagcg cgacggtgac ctgccggaaa
    22681 ggagcggcgg aactggcggc cggactggag gtcgacgtgg tcaagactgc cttcccatcg
    22741 cttgcgcggc cccggcgaga agctgtcccg ccggggccgg aaccgggtgt ggagcgcttt
    22801 cagtcctcga cggcgatcgc ggcggccggg cacaggaacg acgcctcggc gacgccgtca
    22861 cgcagcgcga gcggcggacg cgggtccagc aggacaacgg ccccgtcctc ctcccgctgg
    22921 tcgaacacct ccggggccgc cagcgcgcag tggccggccg cacagcactt ctcctgatcc
    22981 accgagacct tcaccgtggt gttcccctct ccctcagtct tccgtcgttc cggcggccgc
    23041 gccggcctcc gtggtcacca ggcgacgggc acacgggcga cgccgaagtt catcgactcg
    23101 tacagaaacg ccaggtcgtc gagcgggacc tccaggcgca gcgccggaag tcggcgcagc
    23161 agggtctcca gggcgatctg gagctcgacc cgggcgaggg tctgccccag gcactggtgc
    23221 acaccgaagc cgaacccgat gtgctcacgg gcgttcggcc ggcccaggtc cagttcgtgg
    23281 gcgtccgcga agtggggatc gcggttggcg ctgggcaggt tgatgatcac cccttcgccc
    23341 gccgggatga gcaccccgcc gacctcgaca tcctcggcgg ccacccgtcc ggtgccctcc
    23401 tggacgatcg tgatgtaccg gagcagttcg tccaccgcgt tgggcatcag cccgggatcc
    23461 gcccgcagcc gggcgagctg ctcggggtgg cgcagcagca ggacgccgga cagggcgatc
    23521 atgttggccg tggtctcgtg gccggccagc agcagcacca gggcggtggc gaccacctgc
    23581 tgctgggtca gcccgcccgt cagctcctgg tcgacgatga gccggctgag gaggtcgtct
    23641 cccggcgcgg cgcgcttggc cgcacacatc cggctgacgt agtcgaccat gacgccgagc
    23701 gcggcgccca tctcctccgt cgacaccgtg aagtccatga cgccctgcga ggcccgctgg
    23761 aactccgcga agtcggcgtc cgagaccccc agcatcacgg cgatcacctg ggacggcagg
    23821 gggaaggcga agtcggccac caggtcggcc ggcggcccct cggcgatcag ccggtccagg
    23881 aggccgtcga cgatgccctg gatcatcggc cgcatcgcct cggtgcgccg gatggtggag
    23941 tgcgcggtga gcatgcggcg gatccgggcg tgctccggat cgtccatcct cccgaggttg
    24001 aacacctcgg ccggcacctc gaacttggtg aagcgtggca tccccttgtg cgtgccgtcg
    24061 gcgctgaacc tactgtcgcc gagcacggcc cgcgcctcgt gatagccggt gacgagaaag
    24121 ggggtgctgc cgtcccacat ccgcacccgg gtgacggcgg accgctcacg cagttcctcg
    24181 taacccggag ggggtgagaa cgggcatgca gcagcccgca attcggggta gccgcgtatc
    24241 tcgtcagtcc tgtccatccg tccgtcccgt ccgtcgctcc atcgccacca ctgcgccgcc
    24301 ctgcggattg ccaagtctgg tgcgtgcgtc cgcgctccac tcccctaatc actcccctat
    24361 ccccccttgc cccgggcggg gcgggacgct cagcaggagg acgatccggt ggctcctatg
    24421 agcggccaca ggcggcgcga cagatcctgt cgatttccca cggagagctt gcggtagacg
    24481 cgggtcagat gctgctccac ggtgctgacg gtgatgtaga ggctcttggc gatctgccgg
    24541 ttggtcattc tcgacgccgc gagggtggcc acgcgccatt cggcctccga aagtacgggt
    24601 ggctcggcat cttcggccga tgtgcccagg gccgtatcct cgggtacccc gggctccccg
    24661 gaatcctcgg aatttcccgg cggttgaggg tccgccgggc tctcggcacc gcccatgacg
    24721 gggtcccgtc ggctctcgtg ctgggcgctc attccgcact cgtccatcag cttctgcgcc
    24781 tcatgccagg tggcgcgcgc ctgctgggtt tccccggtgc tgaggaagtc ccggctgagt
    24841 tcgacgagcg tgcgggcgag tccataacgg tcgccgtgct cgcgcaggca cttgacggat
    24901 tggtagagca gcagcctgcg tttgtccggg tcctccgcca tggccagtac gcgcagcgct
    24961 ctgccgcggg tgctcatggg gcggtcgggc gacagcttga gctcttccag ggcgagcctt
    25021 ttggcctcca cgggttcatg tacgtgcaga tatgcctcgg cggcgtcgat gcgccagggt
    25081 gccagatcac cgaagtccac gggccactgg tcgatcagca tcccgctcac catgaaatcg
    25141 ttcagcgcgg cataggggcg gttggtggcc aggcagtatt gcccccgggc ccggaggtac
    25201 tccaatccga caacgctgtc gaacatctcc ttcggcaccc agtaacgcag ataccgctgg
    25261 gcctcgtcca gcctgccgat ggcggtgtgg gccgccacca gcacggacag cggtaacccg
    25321 atggcgacgc cccagccgcg tggcgggatg gacctcagcg cggtgccggc gagatcgatg
    25381 gccgaggtga agtccccctg gcggcactgg atataggcac gcatggacag ggcgacggca
    25441 cacggcgtct tcatattgag cttgtccgcc gcggtgaaca gcgccccgca cagccggtcc
    25501 gccgcctccg tctctcccct cgcggccagt gcccagacga tccggcaggc gtacgcgtag
    25561 gcgaaccaga aatggttgga gtgcgacaac aggtgcatgg tgtcggggga gaagtccgcc
    25621 atctgccggg gatcctggag atgcccgatc tccatgccca gttcgtccac ggagagctgg
    25681 agtccgtgct ccagattggc cgcccacagc ccgtcgactt ccctgtccga gggatcctgg
    25741 tcggggaagt ggtggatcag cgtcggtttg aggaaggtga cccactgccg ggtcacccgc
    25801 agcgccgcca tactggacgc attaccggag ccaccactgc ccgacagcca tgtgaaggct
    25861 tcttcgacat cgctgaaccg gccgaaccac agcaccatga agagcaggaa gcacagatac
    25921 tgctcgggga tgtccgcggg ggattcggtc cgtatcgcgg ccatcagccg gtcgagctcg
    25981 ggttcggcgg ccgccggatt gccggcccat aacgcgccga ccagcgccat gcgaatgtcc
    26041 aggcgctccc gccggccgag atcggcgcga gcggccagcc gcagaccggc gaccgcttct
    26101 tccgtacggc cctcgtcgag attcttctgg gccgcgtgcc agagcaccgc cacacccttg
    26161 tgatcaggcg tcttaccggc ggtgaccagg agttccgcga ccgcgatcgg gtcggccccg
    26221 tcggcataca gaagttcggc cgccttcgcg ccgaggcggg cccgctcctc caccgccagc
    26281 gtttccagcg cgacggatcg ggccgcgggg tgccggaagc acccgtcctc caggagccct
    26341 gcggagtcga ggacatcgat ggcccgggcc gcgcgctcct caccgcattc gagcagaccg
    26401 gccacccgcc gcgggctgcc gtacgggccc agtacggcga ggatctgtgc catctggagc
    26461 agcgacggat ggcataacag gctccagcga taggaatccc ggaactccgc tccgaccgtg
    26521 acctctcttt ccgatccgtc cggagcggac atgagatggt cgtgcagcag cgccctcacc
    26581 agccttggat tgccaccgct gatggcgtga caggaggcgc cgatccggtc cgccaggtcg
    26641 gcgtcggcgt gccgctccag cagacgcacg accccggact cggaaagtgt gccgatctcc
    26701 accttgtaga ggttgtggaa tccctgcaca cgggcgcaca gatgatgtgt ccgcccgctg
    26761 gacatcgcga cgagcgtacg ggtgccggac gcatgtctgg cgatatgcag aaggcacatg
    26821 agggaggggt agtcgacatg ctcgacgtca tcgaccgcga tgaccagttg tttgccgccc
    26881 gcgatgcggt gcagcacatc cgatatttca cggaccagca tggccagcat gccgtgttcg
    26941 gcttccgaat accgctcccc cgcggtccgc cagcgcgcca cgacgtccaa ttcccccatg
    27001 gccgcggagg atcggatcag ctgttccacg atattgaagg ggatggcggt gtcttccgcg
    27061 aatccggacg ccgtaagaca gaccgcgtcc gactcggccg cctgctcctc cagactgctc
    27121 aataaggtgg ccttcccgac tccgggtccc ccgaccacct ggagcagccc accgtttccc
    27181 cttgctgccg tgccgagaac gtcgcggagc ctcgattgat aatctgtcag tcccatactc
    27241 atcagtcctc gctgtggggg gttgcgtctg agcgatgagt tgatctccgc ggtcatccca
    27301 ccccgcggaa gaagacttct ctgacgagac agacatccgc tgcgccgacg gcggcgaatt
    27361 ttctgatgtg gatcacctcc ggtggagcct gggtccttga cgttcatata agcagagaca
    27421 caaccggagc gataccttca cccgattgtg acctcagcca cggtttcctg cccccgtgtg
    27481 aacgcgcctg accgagcggg cggcccgccc gcacccggag aagggtggga caccgcctgc
    27541 gccgacgcgc ggaagaaaag cgttcacggc ctgccgacgc gaatacacac ctcagagtct
    27601 gaaccggtta tggacccggc agtattcccc gctcttcgcg aagctggtgg cttaccagca
    27661 gccgccccgg ccggtcaccg ctccgagccc gccacggcgg gctccggatc ggcaagtgcc
    27721 caacccgcgg tcatcctccg gttgccccaa agtcatgtca tgtgtcattg ccggcaacct
    27781 cctcgccctc agcagatatc gcatgccccg actcggtcgc ggagttgcgg ggattgtccc
    27841 ccatatgatc actacgacat cgcgaccata aacggccgcc accccatgat tcccctaaat
    27901 ccttcgcctt gatttggccg ggatttatct gcttgcaaat cggccgaaac ggatgcgccg
    27961 gggaccgatc cggggccgtg ccctcggcat acgatgcccg aagttctggc tactggccag
    28021 atcagagacg agggagcgta aaccgtgacc gtcaagggcg cgctgttcga cttctccggg
    28081 acgctgttcc gaatcgagtc caccgagtcc tggctgcgca ccgtgctgga gcggagccgg
    28141 accgtcctcc cggaggagga gttcgtacgg tacgcacggg ccctggagga cgccggtgcg
    28201 cttcccggcg gcgcggcgcc actcgcggtg ccgccgcctc tggaggaggt gtggggcgta
    28261 cgggaccgca gtgccgagtc gcaccgggcg gcctacaccg gtctggcccg cgaggtgccg
    28321 ctgccccgcc ccgagttcta cgacgccctc tatgac
//
