BGC0000079: X-14547 biosynthetic gene cluster from Streptomyces antibioticus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 79,604 nt. (total: 79,604 nt).
This entry is originally from NCBI GenBank FJ545274.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000079
Short description X-14547 biosynthetic gene cluster from Streptomyces antibioticus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: FJ545274.1
Compounds
  • X-14547
Species Streptomyces antibioticus [taxonomy]
References
Chemical products information
X-14547
Copy SMILES
C31H43N1O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACN69973.1
190 - 954 (+) metallo beta lactamase family protein
copy AA seq
copy Nt seq
  • ACN69974.1
1616 - 1861 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ACN69975.1
1951 - 3240 (-) putative penicillin binding protein
copy AA seq
copy Nt seq
  • ACN69976.1
3383 - 4144 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ACN69977.1
  • idmA
4402 - 5160 (+) type II thioesterase
copy AA seq
copy Nt seq
  • ACN69978.1
  • idmB
5170 - 6759 (+) acyl-CoA carboxylase
copy AA seq
copy Nt seq
  • ACN69979.1
  • idmC
6894 - 8444 (-) efflux transporter
copy AA seq
copy Nt seq
  • ACN69980.1
  • idmD
8437 - 9033 (-) MarR regulatory protein
copy AA seq
copy Nt seq
  • ACN69981.1
  • idmE
9131 - 10840 (-) hydroxybutyryl-CoA dehydrogenase
copy AA seq
copy Nt seq
  • ACN69982.1
  • idmF
10837 - 12213 (-) crotonyl-CoA reductase/carboxylase
copy AA seq
copy Nt seq
  • ACN69983.1
  • idmG
13164 - 15890 (+) LuxR family transcriptional regulator
copy AA seq
copy Nt seq
  • ACN69984.1
  • idmH
16017 - 16454 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ACN69985.1
  • idmI
16756 - 17889 (+) prolyl carrier protein dehydrogenase
copy AA seq
copy Nt seq
  • ACN69986.1
  • idmJ
17886 - 19376 (+) proline adenyltransferase
copy AA seq
copy Nt seq
  • ACN69987.1
  • idmK
19428 - 19703 (+) proline carrier protein
copy AA seq
copy Nt seq
  • ACN69988.1
  • idmL
19774 - 34113 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ACN69989.1
  • idmM
34110 - 44900 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ACN69990.1
  • idmN
44903 - 60547 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ACN69991.1
  • idmO
60601 - 67128 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ACN69992.1
  • idmP
67125 - 74768 (+) polyketide synthase
copy AA seq
copy Nt seq
  • ACN69993.1
75583 - 77058 (+) hypothetical protein
copy AA seq
copy Nt seq
  • ACN69994.1
77084 - 77524 (-) hypothetical protein
copy AA seq
copy Nt seq
  • ACN69995.1
79100 - 79501 (+) putative replication initiation protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added AMP-binding domain substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.