BGC0000107 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000107 (Aspergillus nidulans FGSC A4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	6,819	melanin	Polyketide	100%

BGC0000107 - Region 1 - T1PKS

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Location: 1 - 6,819 nt. (total: 6,819 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 6,820
Label		BGC0000107

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000107.1	0.55	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001265.1	0.24	Polyketide	melanin	Bipolaris oryzae
BGC0001258.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001257.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001284.1	0.22	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001124.1	0.18	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000046.1	0.18	Polyketide	depudecin	Alternaria brassicicola
BGC0001254.1	0.18	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001252.1	0.18	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001906.1	0.17	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000107.1	0.82	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001265.1	0.57	Polyketide	melanin	Bipolaris oryzae
BGC0001258.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001257.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0001284.1	0.55	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001124.1	0.50	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0000046.1	0.50	Polyketide	depudecin	Alternaria brassicicola
BGC0001254.1	0.50	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0001252.1	0.49	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0001906.1	0.49	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01

Similar known gene clusters

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 6819:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ANIA_08209

PKS_AT (912..1212): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 100.0%; Methylmalonyl-CoA: 62.5%; Isobutyryl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 118.6
Methylmalonyl-CoA: 66.2
Methoxymalonyl-CoA: 62.9
inactive: 49.4
Ethylmalonyl-CoA: 39.3
Propionyl-CoA: 37.0
Isobutyryl-CoA: 31.6
2-Methylbutyryl-CoA: 23.6
Benzoyl-CoA: 17.6
fatty_acid: 13.4
CHC-CoA: 10.1
Acetyl-CoA: 9.0
trans-1,2-CPDA: 0.0
3-Methylbutyryl-CoA: 0.0