BGC0000121 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000121 (Pestalotiopsis fici)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	36,243	trypacidin	Polyketide	57%

BGC0000121 - Region 1 - T1PKS

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Location: 1 - 36,243 nt. (total: 36,243 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 36,244
Label		BGC0000121

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000121.1	0.54	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0000013.1	0.27	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.25	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.24	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.24	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906.1	0.23	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001265.1	0.23	Polyketide	melanin	Bipolaris oryzae
BGC0001257.1	0.23	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107.1	0.23	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000121.1	0.87	Polyketide	RES-1214-2	Pestalotiopsis fici
BGC0000013.1	0.60	Polyketide	alternariol	Aspergillus nidulans FGSC A4
BGC0001858.1	0.58	Polyketide	alternapyrone B, alternapyrone C, alternapyrone D, alternapyrone E, alternapyrone F	Parastagonospora nodorum SN15
BGC0001068.1	0.57	Terpene, Polyketide	pyripyropene A	unidentified unclassified sequences.
BGC0001284.1	0.57	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.57	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0001906.1	0.56	Polyketide	naphthalene	Daldinia eschscholzii IFB-TL01
BGC0001265.1	0.56	Polyketide	melanin	Bipolaris oryzae
BGC0001257.1	0.56	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Nodulisporium sp. ATCC74245
BGC0000107.1	0.56	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 25614:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ptaA

PKS_AT (899..1197): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; inactive: 62.5%; Methylmalonyl-CoA: 58.3%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 91.6
inactive: 63.9
Methoxymalonyl-CoA: 52.0
Methylmalonyl-CoA: 50.5
Propionyl-CoA: 39.3
2-Methylbutyryl-CoA: 21.1
Ethylmalonyl-CoA: 18.9
Benzoyl-CoA: 18.4
Isobutyryl-CoA: 17.8
CHC-CoA: 17.2
trans-1,2-CPDA: 13.5
Acetyl-CoA: 10.9
fatty_acid: 10.2
3-Methylbutyryl-CoA: 8.0