BGC0000135: reveromycin A biosynthetic gene cluster from Streptomyces sp. SN-593
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 104,853 nt. (total: 104,853 nt).
This entry is originally from NCBI GenBank AB568601.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000135
Short description reveromycin A biosynthetic gene cluster from Streptomyces sp. SN-593
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: AB568601.1
Compounds
  • reveromycin A
Species Streptomyces sp. SN-593 [taxonomy]
References
Chemical products information
reveromycin A
Copy SMILES
C36H52O11
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAK64627.1
1 - 909 (-) putative amidohydrolase
copy AA seq
copy Nt seq
  • BAK64628.1
954 - 1637 (-) hypothetical protein
copy AA seq
copy Nt seq
  • BAK64629.1
1874 - 2899 (-) putative amidohydrolase
copy AA seq
copy Nt seq
  • BAK64630.1
3134 - 3793 (+) putative transcriptional regulator
copy AA seq
copy Nt seq
  • BAK64631.1
  • revO
4375 - 5676 (+) putative transporter
copy AA seq
copy Nt seq
  • BAK64632.1
  • revP
5725 - 6399 (-) putative transcriptional regulator
copy AA seq
copy Nt seq
  • BAK64633.1
  • revQ
6591 - 7424 (-) putative transcriptional regulator
copy AA seq
copy Nt seq
  • BAK64634.1
  • revR
7941 - 8942 (-) putative 3-oxoacyl-ACP synthase
copy AA seq
copy Nt seq
  • BAK64635.1
  • revS
8942 - 10681 (-) putative CoA ligase
copy AA seq
copy Nt seq
  • BAK64636.1
  • revT
10719 - 12050 (-) putative CoA reductase carboxylase
copy AA seq
copy Nt seq
  • BAK64637.1
  • revB
12672 - 28304 (+) polyketide synthase
copy AA seq
copy Nt seq
  • BAK64638.1
  • revC
28332 - 39506 (+) polyketide synthase
copy AA seq
copy Nt seq
  • BAK64639.1
  • revE
39521 - 40624 (+) putative dehydrogenase
copy AA seq
copy Nt seq
  • BAK64640.1
  • revF
40693 - 42144 (+) putative aldehyde dehydrogenase
copy AA seq
copy Nt seq
  • BAK64641.1
  • revG
42227 - 43048 (+) dihydroxy ketone synthase
copy AA seq
copy Nt seq
  • BAK64642.1
  • revH
43118 - 44641 (-) putative FAD dependent oxidoreductase
copy AA seq
copy Nt seq
  • BAK64643.1
  • revI
44684 - 45877 (-) putative monooxygenase
copy AA seq
copy Nt seq
  • BAK64644.1
  • revJ
45944 - 46954 (-) spiroacetal synthase
copy AA seq
copy Nt seq
  • BAK64645.1
  • revK
47347 - 48279 (+) putative malonyl transferase
copy AA seq
copy Nt seq
  • BAK64646.1
  • revL
48311 - 49384 (+) hypothetical protein
copy AA seq
copy Nt seq
  • BAK64647.1
  • revM
49561 - 50523 (+) putative quinone oxidoreductase
copy AA seq
copy Nt seq
  • BAK64648.1
  • revN
50747 - 51664 (+) putative thioesterase
copy AA seq
copy Nt seq
  • BAK64649.1
  • revA
52185 - 71039 (+) polyketide synthase
copy AA seq
copy Nt seq
  • BAK64650.1
  • revD
71116 - 92208 (+) polyketide synthase
copy AA seq
copy Nt seq
  • BAK64651.1
  • revU
92596 - 95367 (+) putative transcriptional regulator
copy AA seq
copy Nt seq
  • BAK64652.1
95517 - 96494 (-) hypothetical protein
copy AA seq
copy Nt seq
  • BAK64653.1
96795 - 98486 (+) putative transporter
copy AA seq
copy Nt seq
  • BAK64654.1
98486 - 99700 (+) putative transporter
copy AA seq
copy Nt seq
  • BAK64655.1
99718 - 100890 (+) putative peptidase
copy AA seq
copy Nt seq
  • BAK64656.1
100893 - 101957 (+) putative oxidoreductase
copy AA seq
copy Nt seq
  • BAK64657.1
101954 - 102976 (+) putative dehydrogenase
copy AA seq
copy Nt seq
  • BAK64658.1
102995 - 103888 (+) putative hydrolase
copy AA seq
copy Nt seq
  • BAK64659.1
103885 - 104853 (+) hypothetical protein
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.