BGC0000190: A-74528 biosynthetic gene cluster from Streptomyces sp. SANK 61196
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Location: 1 - 28,713 nt. (total: 28,713 nt).
This entry is originally from NCBI GenBank GU937384.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000190
Short description A-74528 biosynthetic gene cluster from Streptomyces sp. SANK 61196
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: GU937384.1
Compounds
  • A-74528
Species Streptomyces sp. SANK 61196 [taxonomy]
References
Chemical products information
A-74528
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C30H24O11
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ADG86308.1
  • san1
 1 - 1695 (-) acyl-CoA decarboxylase
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  • ADG86309.1
  • san2
 1791 - 2819 (+) acyl-ACP-thioesterase
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  • ADG86310.1
  • san3
 2780 - 5578 (-) quinone-forming monooxygenase
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  • ADG86311.1
  • sanC
 5690 - 6430 (+) 3-ketoacyl ACP-reductase
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  • ADG86312.1
  • sanT
 6513 - 8048 (+) peptide transporter
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  • ADG86313.1
  • sanD
 8196 - 8516 (+) polyketide cyclase
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  • ADG86314.1
  • sanE
 8648 - 9073 (+) polyketide cyclase
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  • ADG86315.1
  • sanF
 9070 - 10335 (+) ketosynthase
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  • ADG86316.1
  • sanG
 10332 - 11603 (+) chain length factor
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  • ADG86317.1
  • sanH
 11737 - 11994 (+) acyl carrier protein
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  • ADG86318.1
  • sanI
 11996 - 12451 (+) polyketide cyclase/aromatase
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  • ADG86319.1
  • sanJ
 12448 - 12792 (+) monooxygenase
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  • ADG86320.1
  • sanK
 12789 - 13223 (+) monooxygenase
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  • ADG86321.1
  • sanL
 13447 - 14187 (-) monooxygenase
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  • ADG86322.1
  • sanM
 14316 - 14762 (-) hydroxylase
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  • ADG86323.1
  • sanM1
 14985 - 15452 (+) hydroxylase
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  • ADG86324.1
  • sanN
 15654 - 16706 (+) O-methyltransferase
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  • ADG86325.1
  • sanO
 16807 - 17556 (+) ketoreductase
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  • ADG86326.1
  • sanP
 17549 - 17869 (+) monooxygenase
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  • ADG86327.1
  • sanQ
 17866 - 18183 (+) monooxygenase
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  • ADG86328.1
  • sanS
 18306 - 19313 (-) 3-ketoacyl ACP-synthase
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  • ADG86329.1
  • sanT1
 19331 - 20347 (-) transporter
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  • ADG86330.1
  • sanX
 20585 - 20890 (+) hypothetical protein
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  • ADG86331.1
  • sanR
 21180 - 21611 (-) regulator
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  • ADG86332.1
  • sanU
 21853 - 22293 (+) hypothetical protein
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  • ADG86333.1
  • sanV
 22412 - 24316 (+) asparagine synthetase
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  • ADG86334.1
  • sanR1
 24542 - 26374 (-) regulator
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  • ADG86335.1
  • sanT2
 26608 - 28140 (+) transporter
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  • ADG86336.1
  • sanW
 28234 - 28713 (+) phosphopantetheinyl transferase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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