BGC0000314 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000314 (Pseudoalteromonas piscicida JCM 20779)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,ladderane	1	33,868	alterochromide A / bromoalterochromide A / dibromoalterochromide A / alterochromide B / bromoalterochromide B / dibromoalterochromide B / alterochromide A' / bromoalterochromide A' / dibromoalterochromide A' / alterochromide B' / bromoalterochromide B' / dibromoalterochromide B' / alterochromide A'' / bromoalterochromide A'' / alterochromide B'' / bromoalterochromide B''	NRP	54%

BGC0000314 - Region 1 - NRPS,ladderane

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Location: 1 - 33,868 nt. (total: 33,868 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
ladderane: ladderane

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 33,869
Label		BGC0000314

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000314.1	1.56	NRP, Polyketide, Other, , (, A, m, i, n, o, c, o, u, m, a, r, i, n, )	bromoalterochromide A	Pseudoalteromonas piscicida JCM 20779
BGC0000299.1	1.45	NRP	alterochromide A, bromoalterochromide A, dibromoalterochromide A, alterochromide B, bromoalterochromide B, dibromoalterochromide B, alterochromide A', bromoalterochromide A', dibromoalterochromide A', alterochromide B', bromoalterochromide B', dibromoalterochromide B', alterochromide A'', bromoalterochromide A'', alterochromide B'', bromoalterochromide B''	Pseudoalteromonas piscicida JCM 20779
BGC0000426.1	0.74	NRP	sevadicin	Paenibacillus larvae
BGC0002071.1	0.64	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000389.1	0.62	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000457.1	0.61	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000465.1	0.58	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001629.1	0.58	NRP	Jessenipeptin	Pseudomonas sp. QS1027
BGC0001434.1	0.58	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.58	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000314.1	0.97	NRP, Polyketide, Other, , (, A, m, i, n, o, c, o, u, m, a, r, i, n, )	bromoalterochromide A	Pseudoalteromonas piscicida JCM 20779
BGC0000299.1	0.92	NRP	alterochromide A, bromoalterochromide A, dibromoalterochromide A, alterochromide B, bromoalterochromide B, dibromoalterochromide B, alterochromide A', bromoalterochromide A', dibromoalterochromide A', alterochromide B', bromoalterochromide B', dibromoalterochromide B', alterochromide A'', bromoalterochromide A'', alterochromide B'', bromoalterochromide B''	Pseudoalteromonas piscicida JCM 20779
BGC0000426.1	0.70	NRP	sevadicin	Paenibacillus larvae
BGC0001629.1	0.67	NRP	Jessenipeptin	Pseudomonas sp. QS1027
BGC0002071.1	0.65	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0001434.1	0.65	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.65	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001824.1	0.63	NRP	xefoampeptides A-G	Xenorhabdus beddingii
BGC0001825.1	0.62	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 33868:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-thr) + (D-val - asn) + (D-X - D-leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

PpisJ2_010100002376

Search NORINE for peptide: strict or relaxed

AMP-binding (186..340): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: gFWi-----K
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 30% (weak)

PpisJ2_010100002416

Search NORINE for peptide: strict or relaxed

AMP-binding (457..876): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

PpisJ2_010100002421

Search NORINE for peptide: strict or relaxed

AMP-binding (533..939): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWLGaTFK
Nearest Stachelhaus code:: val, ile
Stachelhaus code match:: 90% (moderate)

AMP-binding (2023..2420): asn

NRPSPredictor2: asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKmGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

PpisJ2_010100002426

Search NORINE for peptide: strict or relaxed

AMP-binding (530..942): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKmGEVGK
Nearest Stachelhaus code:: asn
Stachelhaus code match:: 90% (moderate)

AMP-binding (2031..2439): leu

NRPSPredictor2: leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: leu

Stachelhaus prediction details:

Stachelhaus sequence:: DaFFnGaVYK
Nearest Stachelhaus code:: ile
Stachelhaus code match:: 70% (weak)