BGC0000325: coelichelin biosynthetic gene cluster from Streptomyces coelicolor A3(2)
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Location: 510,823 - 533,448 nt. (total: 22,626 nt).
This entry is originally from NCBI GenBank AL645882.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000325
Short description coelichelin biosynthetic gene cluster from Streptomyces coelicolor A3(2)
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AL645882.2
Compounds
  • coelichelin
Species Streptomyces coelicolor A3(2) [taxonomy]
References
Chemical products information
coelichelin
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C21H39N7O11
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAB53319.1
  • SCO0489
 510823 - 511035 (-) conserved hypothetical protein
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  • CAB53320.1
  • SCO0490
 511124 - 512215 (+) putative esterase
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  • CAB53321.1
  • SCO0491
 512302 - 513924 (-) putative ABC transporter transmembrane protein
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  • CAB53322.1
  • SCO0492
 513989 - 524920 (-) putative peptide synthetase
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  • CAB53323.1
  • SCO0493
 524978 - 526783 (-) putative ABC-transporter transmembrane protein
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  • CAB53324.1
  • SCO0494
 526786 - 527838 (-) putative iron-siderophore binding lipoprotein
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  • CAB53325.1
  • SCO0495
 527889 - 528752 (-) putative iron-siderophore ABC-transporter ATP-binding protein
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  • CAB53326.1
  • SCO0496
 528791 - 529897 (-) putative iron-siderophore permease transmembrane protein
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  • CAB53327.1
  • SCO0497
 529894 - 530970 (-) putative iron-siderophore permease transmembrane protein
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  • CAB53328.1
  • SCO0498
 530970 - 532325 (-) putative peptide monooxygenase
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  • CAB53329.1
  • SCO0499
 532501 - 533448 (+) putative formyltransferase
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
SCO0492
Module ?
Specificity: N5-formyl-N5-hydroxyornithine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: N5-hydroxyornithine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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