BGC0000335: cystomanamide A biosynthetic gene cluster from Cystobacter fuscus
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Location: 1 - 37,509 nt. (total: 37,509 nt).
This entry is originally from NCBI GenBank KJ710244.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0000335
Short description cystomanamide A biosynthetic gene cluster from Cystobacter fuscus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: KJ710244.1
Compounds
  • cystomanamide A
  • cystomanamide B
  • cystomanamide C
  • cystomanamide D
Species Cystobacter fuscus [taxonomy]
References
Chemical products information
cystomanamide A
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C28H44N6O9
Chemical database entries
NPAtlas
cystomanamide B
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C40H57N7O14
Chemical database entries
NPAtlas
cystomanamide C
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C34H54N6O14
Chemical database entries
NPAtlas
cystomanamide D
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C34H54N6O13
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AID65218.1
 164 - 1054 (+) JmjC domain-containing protein
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  • AID65219.1
 1159 - 2589 (+) beta-lactamase
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  • AID65220.1
 2682 - 3968 (+) beta-lactamase
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  • AID65221.1
 3972 - 5441 (+) beta-lactamase
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  • AID65222.1
  • ctmA
 5528 - 18073 (+) putative aspartate racemase
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  • AID65223.1
  • ctmB
 18088 - 19098 (+) putative taurine catabolism dioxygenase
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  • AID65224.1
  • ctmC
 19123 - 26763 (+) nonribosomal peptide synthetase
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  • AID65225.1
  • ctmD
 26793 - 35432 (+) nonribosomal peptide synthetase
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  • AID65226.1
 35486 - 36460 (-) short chain dehydrogenase
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  • AID65227.1
 36480 - 37469 (+) LysR family transcriptional regulator
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ctmA
Module ?
Specificity: asparagine
Evidence for specificity:
ctmC
Module ?
Specificity: asparagine
Evidence for specificity:
Module ?
Specificity: phenylalanine / S-beta-hydroxyphenylalanine
Evidence for specificity:
  • Structure-based inference
ctmD
Module ?
Specificity: tyrosine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: CUSGWVK3I4TVHJH7NHPFAP2L, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added missing polyketide class
  • Added NRP substrate specificities
Detailed domain annotation
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