BGC0000347: equibactin biosynthetic gene cluster from Streptococcus equi subsp. equi
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Location: 36,024 - 59,836 nt. (total: 23,813 nt).
This entry is originally from NCBI GenBank AM909652.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000347
Short description equibactin biosynthetic gene cluster from Streptococcus equi subsp. equi
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AM909652.1
Compounds
  • equibactin
Species Streptococcus equi subsp. equi [taxonomy]
References
Chemical products information
equibactin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SEQ1246
  • CAP20360.1
  • eqbA
36024 - 36404 (+) putative iron-dependent regulatory protein
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  • SEQ1245
  • CAP20361.1
  • eqbB
36633 - 37382 (+) putative non-ribosomal peptide synthesis thioesterase
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  • SEQ1244
  • CAP20362.1
  • eqbC
37369 - 38052 (+) putative 4'-phosphopantetheinyl transferase superfamily protein
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  • SEQ1243
  • CAP20363.1
  • eqbD
38061 - 39644 (+) equibactin siderophore biosynthetic protein
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  • SEQ1242
  • CAP20364.1
  • eqbE
39659 - 45730 (+) equibactin equibactin nonribosomal peptide synthase protein
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  • SEQ1241
  • CAP20365.1
  • eqbF
45727 - 47853 (+) equibactin biosynthetic protein
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  • SEQ1240
  • CAP20366.1
  • eqbG
47837 - 51655 (+) equibactin nonribosomal peptide synthase protein
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  • SEQ1239
  • CAP20367.1
  • eqbH
51645 - 52232 (+) putative membrane protein
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  • SEQ1238
  • CAP20368.1
  • eqbI
52234 - 52905 (+) putative transmembrane protein
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  • SEQ1237
  • CAP20369.1
  • eqbJ
52919 - 54295 (+) putative ABC transporter ATP-binding component
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  • SEQ1236
  • CAP20370.1
  • eqbK
54318 - 56075 (+) ABC transporter, ATP-binding membrane protein
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  • SEQ1235
  • CAP20371.1
  • eqbL
56080 - 57825 (+) ABC transporter ATP-binding membrane protein
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  • SEQ1234
  • CAP20372.1
  • eqbM
57845 - 58909 (+) putative oxidoreductase
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  • SEQ1233
  • CAP20373.1
  • eqbN
58931 - 59836 (+) putative membrane protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
eqbD
Module ?
Specificity: salicylic acid
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
eqbE
Module ?
Specificity: cysteine
Evidence for specificity:
  • Sequence-based prediction
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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