LOCUS       BGC0000348             19379 bp    DNA     linear   PLN 14-JUL-2016
DEFINITION  Neotyphodium lolii strain Lp19 EAS ergot alkaloid biosynthetic gene
            cluster, partial sequence.
ACCESSION   BGC0000348
VERSION     BGC0000348
KEYWORDS    .
SOURCE      Epichloe festucae var. lolii
  ORGANISM  Epichloe festucae var. lolii
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae;
            Epichloe.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:34:03
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     mRNA            <1..>558
                     /gene="easH"
                     /product="putative dioxygenase"
     gene            <1..>558
                     /gene="easH"
     CDS             <1..558
                     /codon_start=1
                     /gene="easH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /product="putative dioxygenase"
                     /protein_id="ABM91453.1"
                     /sec_met_domain="PhyH (E-value: 2.2e-17, bitscore: 52.7,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="YGAAIENGPGTQEQIWHRDQPDYALLKAGPGTAEAMLNFFTALTD
                     FTPDTGMTQYIWGSHKRVELGEPDAEHPVVFTKLKAGDTAVLSGKIVHRGSANATPDVF
                     RRALALMIIPAIMTPFDATCHLSRHMVETMTPLAQKMVGRRSVVIPPPHTVGAALGIWC
                     LNMREVGEQMGLKSNQPDKEEE"
     source          1..19379
                     /db_xref="taxon:73839"
                     /mol_type="genomic DNA"
                     /organism="Epichloe festucae var. lolii"
                     /strain="Lp19"
                     /variety="lolii"
     misc_feature    <1..>19379
                     /note="EAS ergot alkaloid biosynthetic gene cluster"
     protocluster    1..19379
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[9410:13540]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9411..13540
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..19379
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..19379
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000348"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19379
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     mRNA            complement(<1019..>2161)
                     /gene="easA"
                     /product="putative oxidoreductase"
     gene            complement(<1019..>2161)
                     /gene="easA"
     CDS             complement(1019..2161)
                     /codon_start=1
                     /gene="easA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     369.8; E-value: 2.2e-112)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxidoreductase"
                     /protein_id="ABM91449.1"
                     /transl_table=1
                     /translation="MSTSNLFTPLQFGKCLLQHKLVLSPMTRFRADNEGVPLPYVKTYY
                     CQRASLPGTLLLTEATAISRRARGFPNVPGIWSQEQIAGWKEVVDAVHAKGSYIWLQLW
                     ATGRAAEVGVLKANGFDLVSSSAVPVSPGEPTPRALSDDEINSYIGDFVQAAKNAVLEA
                     GFDGVELHGANGFLIDQFLQSPCNQRTDQWGGCIENRSRFGLEITRRVIDAVGKDHVGM
                     KLSTWSTFQGMGTMDDLIPQFEHFIMRLREIGIAYLHLANSRWVEEEDPTIRTHPDIHN
                     ETFVRMWGKEKPVLLAGGYGPESAKLVVDETYSDHKNIGVVFGRHYISNPDLPFRLKMG
                     LPLQKYNRETFYIPFSDEGYLDYPYSEEYITENKKQAVLA"
     mobile_element  2521..2661
                     /mobile_element_type="transposon:Toru1.1; putative
                     miniature inverted-repeat transposable element (MITE)"
     repeat_region   2827..2915
                     /rpt_type=tandem
                     /rpt_unit_seq="tataatatac"
                     /satellite="satellite"
     mobile_element  2926..3064
                     /mobile_element_type="transposon:Toru1.2; putative
                     miniature inverted-repeat transposable element (MITE)"
     mRNA            join(<3517..3997,4075..4274,4327..>4575)
                     /gene="easG"
                     /product="conserved protein EasG"
     gene            <3517..>4575
                     /gene="easG"
     CDS             join(3517..3997,4075..4274,4327..4575)
                     /codon_start=1
                     /gene="easG"
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 204.4; E-value: 4.2e-62)"
                     /gene_kind="other"
                     /product="conserved protein EasG"
                     /protein_id="ABM91452.1"
                     /transl_table=1
                     /translation="MVQIYLPRLSMRLGYHDKNNKMTILLTGGRGKTASHIASLLQAAK
                     VPFIVASRSSDPSSSSPYYQNCFDWLDEKTYGDVLTSKDSMQPISTIWLVPPPIFDLAP
                     LMIKFVDFASRKGVKRFVLLSASTIKKGGPAMGQVHEYLASLGGIEYAVLRPTWFMENF
                     SYPQELQRLAIKNENKIYSAAGDGKLPFVSVADIARVAFRTLTDEKSHNTDYVLLGPEL
                     ITYDQVAETLSTVLGRTITHIKLTEEELVKRLENSGMPAEDAKMLAGMDTSISDGAEDR
                     LNNVVKHVTGADPRTFLDFATHQKATWG"
     mRNA            complement(join(<4619..5387,5456..>5721))
                     /gene="easF"
                     /product="conserved protein EasF"
     gene            complement(<4619..>5721)
                     /gene="easF"
     CDS             complement(join(4619..5387,5456..5721))
                     /codon_start=1
                     /gene="easF"
                     /product="conserved protein EasF"
                     /protein_id="ABM91451.1"
                     /transl_table=1
                     /translation="MSKPNVLDIRLATFEDSIVDLVINGLRKQPKTLPALLFYANEGLK
                     HWNHHSHQPEFYPRHQEVQILKKKAQEMAASIPMNSVVVDLGSASLDKVIHLLEALEVQ
                     KKNISYYALDVSASQLESTLAAIPTQNFRHVRFAGLHGTFDDGLHWLKEAPEARDVPHT
                     VLLFGLTIGNFSRPNAAAFLSNIGQHAFQGKSGDQCSILMSLDSCKVPTQVLRAYTCEG
                     VVPFALQSLTYANGLFSEKNKTQASGDVQHKVFNLDEWYYLSEWNFVLGRHEASLIPRS
                     KDIKLLPPLDGILVSKDEKVRFGCSYKYDQEERMELFAAAGVKNEVTWSDEGCDVAFYQ
                     LKLS"
     mRNA            complement(join(<6190..7203,7263..7795,7870..>8140))
                     /gene="easE"
                     /product="putative oxidoreductase"
     gene            complement(<6190..>8140)
                     /gene="easE"
     CDS             complement(join(6190..7203,7263..7795,7870..8140))
                     /codon_start=1
                     /gene="easE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138:FAD linked oxidase domain protein (Score: 351.9;
                     E-value: 1.4e-106)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative oxidoreductase"
                     /protein_id="ABM91450.1"
                     /transl_table=1
                     /translation="MRHFVTFVVGFLLSWGFLSSLQDPPSCRCRPWEPCWPDSHQWTSL
                     NASIDGNLVHVQPVGSVCHDPHYDAVACGDVLDLSRNSGWRASNPATLQDWIWETGSGD
                     NESCLLVSSSERPQEIPCHQGRLPLYSAAVKSTAHVQGVIRFAKDHNLRLVIKNTGHDA
                     TGRSAAPDSLQIHTYFLKDIHYDDNFLVHGDATGSGPAVTLGAGVVHSEVYKHGIDHKY
                     SVVGGECPTVGIVGGFLQGGGVSSWSGFTRGLAVDNVLEYQVVTANAELVIANEHQNQD
                     LFWALRGGGGGTFGVVTQATVRAFPDDPTVVSTLVLSSTRADTSFWVKAISRLLSILRS
                     CNQQNVHGQLIITRPSVDILNAGLTLHFSNMTNVLHAETLLQPHIASLSEDQISTTLTS
                     KFVANINSELRLDADIHPRGIGTLQTSMMISNELFGSSEGPLTVAQVFGKLPIGPNDLL
                     FTSNLGGCIAANKGLDTAIHPAWRSSAHLVTYVRSVEPSIEAKKLALKEITNKYMPILY
                     SMQPSFKVSYRNLGDPNEKNYQEVFWGEKVYKRLASIKAKLDPDGLFISKLGVGSEDWD
                     TEGMCYQPQNRVSQPLRSLKYFLSVLKDT"
     mobile_element  8351..8591
                     /mobile_element_type="transposon:Ono; putative mobile
                     element"
     mobile_element  8689..8983
                     /mobile_element_type="transposon:Rima; miniature
                     inverted-repeat transposable element (MITE)-like"
     mRNA            join(<9411..10004,10079..>13540)
                     /gene="lpsB"
                     /product="lysergyl peptide synthetase LpsB"
     gene            <9411..>13540
                     /gene="lpsB"
     CDS             join(9411..10004,10079..13540)
                     /NRPS_PKS="Domain: AMP-binding (287-684). E-value: 1.6e-78.
                     Score: 255.9. Matches aSDomain:
                     nrpspksdomains_lpsB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (833-902). E-value: 4.5e-20. Score:
                     63.5. Matches aSDomain: nrpspksdomains_lpsB_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (940-1205). E-value:
                     1.1e-26. Score: 85.5. Matches aSDomain:
                     nrpspksdomains_lpsB_Condensation_DCL.1"
                     /codon_start=1
                     /gene="lpsB"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     249.3; E-value: 1e-75)"
                     /gene_kind="biosynthetic"
                     /product="lysergyl peptide synthetase LpsB"
                     /protein_id="ABM91454.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-30, bitscore:
                     94.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-91, bitscore:
                     294.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.7e-13, bitscore:
                     39.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MQSQVRLPSNGNPALSFPQNEIGGPVHWKTYLEGCSPCSFPSLRT
                     VCPSQSWPASVSITIGDSIFRRLEHFSDKTGISVATVFRASWGLVLRIYTGQDSVCFGD
                     MTTAPGGIDAIGCVGVCRVELSDTAVISKVLQRIQAASANKLAIPHVPLSDAVLSKCMP
                     SASLFNTCMLISGGGERPEKTSSTFEKVELGYDDQYDIIVRGSVEDSGASAALSYRTSF
                     LSEEQATSIANTFERAVSDLIGIENRIGQICFLSDLDKSQIYTWNKDPPLRAHSCVDTL
                     IHERCLSQPTASAVNAWDGELSYEELNHLSSKLSRHLVTLGVGAEVFVPLCFEKSRWTT
                     VAMLAVIKAGGAFVLLDPSHPAERLLSICQKVSARLIVASAQHAKLAEDLVTSIVEVGD
                     DKADWLTDKGIKAQTQTRTRRSAAPGDALYAVFTSGSTGTPKGVIIEHGSFHAAVFPYT
                     EAVGLNQESRVFQFSSYAFDVTIFDTLMTLISGGCVCVPSNTERWSDVANAIQRFRVTH
                     SSLTPTVARILDPKDVLTLRTLVLGGEKLVTSDITKWVDQVRLVHLYGASECPIMSIQS
                     MTGVASDFQTTDHATGSNCWIVDPNNHDRLVPIGTIGELVIEGTIVGRGYLDDPEKSSA
                     TFIRPPGWLCQVRGSGYHSAVYKSGDLVQYTADGSLRYIGRKDTQVKLRGQRVELGEVE
                     HHVKLTFPNATDVVVELVVTIHASSSRAPILVAFVLISHEADPDPESIRTGRGEGLSQI
                     LSEPTDRFCSQIPIVQSQLQQSLPSYMVPGIFLPLMTLPLTSTDKINRKLLRELAGALS
                     REELESYQPSTGPVRAPQTTTEKLLQQYFARVLNIPVEQVGADDHFFQRGGDSLTAMKL
                     VAMARKDKHKLTVQDIFDSPRLSALACVVRSGKVDGNKEPPLEPFSLVNKHRDIIRAAA
                     QQCQLPVRVIEDVYPCTPLQRGLISETLRDSKAFIAHLAVSLPPDIDLQRLQEAWTTVA
                     NANPILRTRMVLSASHGLLQVVVREDIRWIVSKNAEAQDFFVGVGKPLVQLVLCCHREG
                     NEVPVQLLLMVHHAVYDGYTLPLIFEQVKAAYNGGTLAPRPAVPFIRYVQSIPDGTGYW
                     NSLMANLQTPIFPALPSKSYQPLPNAIMRHTIITPGSHRQYTPSTYVRLAWAITQAYHQ
                     GTCDIFFGTVVSGRNAPVTDIELMTIPTVATIPCRVTLDFQSLVQSALRKIQDDAISGI
                     PFEQLGLPHIRRLGEHAMLACSFQTLLSIQPALPPSTDAWFEQPGSTIDYRANATYAIN
                     LFFGLEGDKLKATALYDFNVVKKDKMQSMLVDFGNILQTMHKSPNSLIRDILAVPQQMR
                     GPINSASL"
     aSDomain        10346..11536
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_lpsB_AMP-binding.1"
                     /evalue="1.60E-78"
                     /label="lpsB_AMP-binding.1"
                     /locus_tag="lpsB"
                     /protein_end="684"
                     /protein_start="287"
                     /score="255.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="SQPTASAVNAWDGELSYEELNHLSSKLSRHLVTLGVGAEVFVPLC
                     FEKSRWTTVAMLAVIKAGGAFVLLDPSHPAERLLSICQKVSARLIVASAQHAKLAEDLV
                     TSIVEVGDDKADWLTDKGIKAQTQTRTRRSAAPGDALYAVFTSGSTGTPKGVIIEHGSF
                     HAAVFPYTEAVGLNQESRVFQFSSYAFDVTIFDTLMTLISGGCVCVPSNTERWSDVANA
                     IQRFRVTHSSLTPTVARILDPKDVLTLRTLVLGGEKLVTSDITKWVDQVRLVHLYGASE
                     CPIMSIQSMTGVASDFQTTDHATGSNCWIVDPNNHDRLVPIGTIGELVIEGTIVGRGYL
                     DDPEKSSATFIRPPGWLCQVRGSGYHSAVYKSGDLVQYTADGSLRYIGRKDTQVKLR"
     aSModule        10346..12190
                     /complete
                     /domains="nrpspksdomains_lpsB_AMP-binding.1"
                     /domains="nrpspksdomains_lpsB_PCP.1"
                     /locus_tags="lpsB"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10514..10555
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0001"
                     /evalue="7.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="lpsB"
                     /protein_end="357"
                     /protein_start="343"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LAVIKAGGAFVLLD"
     CDS_motif       10769..10825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0002"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="lpsB"
                     /protein_end="447"
                     /protein_start="428"
                     /score="27.1"
                     /tool="antismash"
                     /translation="YAVFTSGSTGTPKGVIIEH"
     CDS_motif       11306..11395
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0003"
                     /evalue="6.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="lpsB"
                     /protein_end="637"
                     /protein_start="607"
                     /score="37.7"
                     /tool="antismash"
                     /translation="PIGTIGELVIEGTIVGRGYLDDPEKSSATF"
     CDS_motif       11501..11566
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0004"
                     /evalue="5.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="lpsB"
                     /protein_end="694"
                     /protein_start="672"
                     /score="37.5"
                     /tool="antismash"
                     /translation="YIGRKDTQVKLRGQRVELGEVE"
     aSDomain        11984..12190
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_lpsB_PCP.1"
                     /evalue="4.50E-20"
                     /label="lpsB_PCP.1"
                     /locus_tag="lpsB"
                     /protein_end="902"
                     /protein_start="833"
                     /score="63.5"
                     /tool="antismash"
                     /translation="EKLLQQYFARVLNIPVEQVGADDHFFQRGGDSLTAMKLVAMARKD
                     KHKLTVQDIFDSPRLSALACVVRS"
     aSDomain        12305..13099
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_lpsB_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="1.10E-26"
                     /label="lpsB_Condensation_DCL.1"
                     /locus_tag="lpsB"
                     /protein_end="1205"
                     /protein_start="940"
                     /score="85.5"
                     /tool="antismash"
                     /translation="EDVYPCTPLQRGLISETLRDSKAFIAHLAVSLPPDIDLQRLQEAW
                     TTVANANPILRTRMVLSASHGLLQVVVREDIRWIVSKNAEAQDFFVGVGKPLVQLVLCC
                     HREGNEVPVQLLLMVHHAVYDGYTLPLIFEQVKAAYNGGTLAPRPAVPFIRYVQSIPDG
                     TGYWNSLMANLQTPIFPALPSKSYQPLPNAIMRHTIITPGSHRQYTPSTYVRLAWAITQ
                     AYHQGTCDIFFGTVVSGRNAPVTDIELMTIPTVATIPCRVTLD"
     CDS_motif       12374..12478
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0005"
                     /evalue="4.60E-07"
                     /label="C2_DCL_024-062"
                     /locus_tag="lpsB"
                     /protein_end="998"
                     /protein_start="963"
                     /score="22.1"
                     /tool="antismash"
                     /translation="FIAHLAVSLPPDIDLQRLQEAWTTVANANPILRTR"
     CDS_motif       12659..12724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0006"
                     /evalue="9.90E-05"
                     /label="C3_DCL_135-156"
                     /locus_tag="lpsB"
                     /protein_end="1080"
                     /protein_start="1058"
                     /score="15.0"
                     /tool="antismash"
                     /translation="VHHAVYDGYTLPLIFEQVKAAY"
     CDS_motif       12992..13087
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_lpsB_0007"
                     /evalue="4.60E-08"
                     /label="C5_DCL_263-294"
                     /locus_tag="lpsB"
                     /protein_end="1201"
                     /protein_start="1169"
                     /score="25.6"
                     /tool="antismash"
                     /translation="DIFFGTVVSGRNAPVTDIELMTIPTVATIPCR"
     misc_feature    14141..19379
                     /note="Region: AT-rich"
ORIGIN
        1 tatggcgctg ccatcgaaaa tggccctggc acacaggagc agatatggca tcgtgaccag
       61 cctgattacg ctttgcttaa agccggtcct ggcaccgccg aggctatgct taattttttc
      121 actgccttaa ccgactttac tcctgacact ggcatgacac agtatatctg gggcagccac
      181 aagagggtgg aattgggcga gcccgatgct gagcatcctg tcgtgttcac gaagctcaag
      241 gcaggcgaca cggcagtact gagcggcaag atagtgcatc ggggtagcgc aaatgcaaca
      301 cctgatgtct ttcgccgggc actggcgtta atgattatac ctgccatcat gacaccattt
      361 gatgctacat gccatctttc tcggcacatg gtcgagacta tgacaccgct ggcgcagaag
      421 atggttggta ggcgaagtgt ggtgatccca ccgcctcata cggttggagc tgcgcttgga
      481 atttggtgtt tgaatatgag ggaggttggg gagcagatgg gcttgaaatc caatcaacct
      541 gacaaggagg aagaataatg ttatctgtct cacgctcgat ttctgttctc tattttcaat
      601 tctcttatct aatcctcgct ctattcactc cttgggttat cctaccgact acaataacaa
      661 ccaaacaaga tagttaggtg atggccaatc ctgttatcct ttaaattgcg cgactcggct
      721 cgacgtgctt gagcatggat agctagggtt tgtacgtatc accgagacaa agaggcgcat
      781 cattcactat caattatttt cagagatatc taaatgaaac aaaatgacta cagtattgta
      841 taatgatcac ggagcaccaa agactaagaa gacaatgata aagataactt aatgaacgaa
      901 atacaaaagc cataccacac tagtgtacct attcggtata agatttaact cttagaggaa
      961 tcatttataa ggctaatcca aaagaatgca aaagcattgc ctggactgcg ataatgattt
     1021 atgctagaac tgcctgcttc ttgttctctg ttatgtattc ctcactatag gggtaatcca
     1081 agtatccctc gtcagagaac ggaatgtaga aagtttcccg attgtacttt tgaagaggga
     1141 gtcccatttt cagccggaat ggaagatctg ggttggatat atagtgtcgt ccaaaaacga
     1201 caccgatgtt cttgtggtca gagtatgttt catctaccac aagcttggcg gactccgggc
     1261 cgtagccacc agccaaaagg acaggcttct ctttccccca catgcgcaca aaagtctcat
     1321 tatgaatatc tggatgtgtt ctgatggtgg ggtcttcctc ctctacccag cgagagttag
     1381 caaggtgtag ataggcaatg cctatctcac gaaggcgcat gatgaaatgc tcgaactgag
     1441 gtatgaggtc gtccatggtg cccattccct ggaaggtact ccaagtggaa agcttcatgc
     1501 ccacatggtc tttaccgaca gcgtcgatga ctcgccgggt gatttcaaga ccgaaccgtg
     1561 agcgattctc aatgcaaccg ccccattgat cggtacgttg gttgcaagga gattggagaa
     1621 actgatcgat gagaaatcca ttggcaccgt ggagttcgac tccgtcaaat cctgcttcta
     1681 ggactgcatt tttggctgct tgaacgaaat caccgatgta tgagttgatc tcatcgtcgc
     1741 tgagcgcccg gggtgtgggc tcaccggggg agactggaac ggcactgctg gatacgagat
     1801 caaatccatt cgctttcaga acaccaacct cggctgctcg tccagtcgcc caaagctgca
     1861 gccagatata agaccccttc gcatgcacag catcaactac ctctttccag cctgcaattt
     1921 gctcctgact ccaaatcccg gggacattgg gaaaccctct ggctcggcga gagatggcag
     1981 tagcttcggt aagaagcagg gtgccaggga gagatgctcg ttgacagtag taagtcttga
     2041 catagggaag cgggacgcct tcattatccg cacgaaaacg agtcatcggt gagaggacta
     2101 gcttgtgctg gaggagacat tttccaaatt ggagcggcgt gaaaagattt gaagttgaca
     2161 taatgatgcg caaacacagc tagcttcaca acctggttct gtaaagaatg aagatcttct
     2221 agcaaaaagc ttcataatca cagctaaaag agacgtccag aggatttttc catctcacga
     2281 ttgcaatccg aggtcctaag aagcttgaac catgtagcat acatgggcct ctacaatgtg
     2341 atgtcacgtt aaccccggac aaataccaca gatgcaagac atgggaactg ctagctatta
     2401 aaagcatgaa agtatgcaag ctagagtgct tgaagcaggg caagatgcca atgagcgggt
     2461 cctttctttg tctagtataa cctagctttc aggctagctc cgctccgagc tgcgcccact
     2521 atctccttga gcgtgttaaa gctagtggag tcacgttaac tagggtctgt atgtatctct
     2581 agtttacttt tatctaattg gatacataca gaccctagtt aacgtgactc cactagcttt
     2641 acataacacg ctaaaggaga tggcctagat ttatttttag cgggacttcg gtacaattac
     2701 ttaggtcact aaacgagcac atcgcgtttt ttcaatgcgt atatctcgta aggtacgcaa
     2761 ggcctaacaa cgcaacgcaa taacgcaacg gtatataacc taacgtaata taacataaca
     2821 taggaatata atatactata atatactata atatactata atatactata atatactata
     2881 atatactata atatactata atatactata atataatata gtcctatctc ctaaactatt
     2941 attcaccttg tgaagtcacg ttaactaggg tctgtaatgt atctctagtt tacttttacc
     3001 taattggtta catacagacc cctagttaac gtgactccac aagccatatc acgactaagg
     3061 agatagggga tataactcgc agaaactaga gactagtcgg ctgcgcctct tttttctagt
     3121 gcaacagatt agagtccaag gagatagtgc agatgcaagg cctacatgta agctaagccg
     3181 ctcgcaagac ttgccgagct ctttcactgt ctttaccgca gaggaatgca catgcatatg
     3241 cactagggtg gcctcgaagt aaccctccgt ggtgctttta atacccccta gcatagaaaa
     3301 tacctgcatt gaaaggcgca tggtctcggc cgccaaattc tcacgcaaac aagatattgg
     3361 ggcacatggg attgcgtgaa tttgtggcaa aattgctcaa gggatgctta gttgctgtgg
     3421 tagatgcaaa agccaaaatc gttctccatg tgtagttcat gttaatcccc cctaccggag
     3481 tagatcttaa cattctggtt ctgacgattg tcccatatgg tccagatata tttgccaaga
     3541 ctctccatga gattgggata ccacgacaag aacaacaaaa tgactattct tctgactggt
     3601 ggtcgaggca agacagccag ccatattgcc tctcttctcc aggcggccaa ggtgcctttt
     3661 atcgttgctt cacgctcgtc agatcctagc tcgagctcgc cttactacca aaattgcttc
     3721 gactggctgg acgagaagac gtacggcgat gtactcacat caaaagatag tatgcagcca
     3781 atatcaacaa tttggcttgt tccgccaccc atctttgact tagctccatt gatgatcaag
     3841 tttgttgatt ttgcgagccg caagggagtc aagagatttg tgctgttaag tgctagcaca
     3901 attaagaaag gtggacctgc catgggacag gttcacgaat atttagcgtc tttaggggga
     3961 attgagtacg ctgtattaag accgacgtgg tttatgggta tgaccttagg aaaagccgcc
     4021 gggatatgaa gtagcctagc taacccgagg ttaatgtgct aatttttctt ttagaaaatt
     4081 tttcatatcc acaggaactt caacgcctcg cgattaagaa cgagaacaag atctattctg
     4141 ccgcaggcga cggaaagttg ccgtttgtct ccgtggcaga tattgcccgt gtcgcattcc
     4201 gcacattaac ggatgagaag tcacataaca cagactacgt tctcctaggg cctgagctaa
     4261 taacatacga ccaggtatga ctatttgtca gttagaacaa agaatgaaat taacgtataa
     4321 cgataggttg ctgaaacatt gtccacggtt ctcggcagaa ctatcactca tatcaagctc
     4381 acagaggagg agcttgtgaa gcgcttagaa aatagtggta tgccagctga ggacgcaaaa
     4441 atgctagccg gaatggacac aagcattagt gatggtgcag aagatagact gaacaatgtg
     4501 gtcaagcatg taacaggtgc agatcctcgt acttttttgg attttgctac tcatcagaag
     4561 gcaacctggg gctaaataaa gtccttgtta tacaatagag accgcgaaaa gggaaaaatc
     4621 agcttagctt taactgataa aatgcgacat cgcatccttc atccgaccac gtaacttcat
     4681 tcttcacccc agcagctgca aatagctcca ttcgctcctc ttgatcgtat ttgtagctgc
     4741 agccaaagcg cactttttcg tctttgctaa ctaatatccc gtccagtggc ggaagtagtt
     4801 taatgtcttt tgatcgtgga atcagtgaag cttcatgtct tccgagaaca aaattccatt
     4861 cgctaaggta gtaccattca tcaagattga agactttgtg ttggacatca ccactggctt
     4921 gtgtcttgtt cttctcgctg aaaaggccgt tagcgtatgt aagcgactgt agcgcaaacg
     4981 ggacaactcc ctcgcaggtg tatgccctca aaacctgcgt tgggactttg caactgtcca
     5041 gactcatcag aatcgagcat tggtcgcctg acttgccctg aaaggcatgc tggccgatgt
     5101 tactcaagaa tgctgctgca ttgggtcgtg agaagttgcc gattgtgagt ccaaataaca
     5161 gtactgtgtg tggtacatca cgggcctctg gcgcctcttt gagccagtgt aagccatcat
     5221 caaaggtccc atgtagccca gcgaaacgga catgacgaaa gttctgggtc ggaatggctg
     5281 ccagcgtgga ctcaagctgc gaggcactta cgtccagggc gtaataagag atgttctttt
     5341 tctggacttc aagagcttct agaagatgaa tgaccttgtc taggctccta aattgatata
     5401 agagttgtat tagcagcaac ttcaaccgct ttgcagggta aatccgtttt ctcacgcgct
     5461 accgaggtcc acaacaacac tattcatagg aatagaggcg gccatctcct gtgccttttt
     5521 ttttaagatt tggacctcct gatgtcgcgg gtaaaattct ggctgatgtg agtggtggtt
     5581 ccaatgtttc aacccttcgt tggcgtagaa gagaagggcg ggaagtgtct tcggttgctt
     5641 gcgaaggcca ttgatgacaa gatcgacaat tgagtcctca aatgtagcaa gacgaatgtc
     5701 gagaacgttt ggcttactca tggttgtggt taattatata tataaccaga tagttgataa
     5761 taatgaaacg tcttgatgca ggaaaaaaaa aggcttgaaa tttagtggcg aggagggaca
     5821 ttgctagcca tgacgcactc acgagtggta tgtgtggagc aacacggggc acgacttttg
     5881 gcccccctag tatttagtat atggacacca caaacctgca aagacagacc catgaggttc
     5941 cttttctgtt agcatactca cgcgttcaca ttgtgcactt aatacacccg ttgtcttttc
     6001 cgcacaagta atgtggcaga tactaggcgg ggcttgcgag gctagatatt agcaaagtat
     6061 tgaaataaca tttgtctcat gatatgttat atggctaaat gacgtcgaga gcctagaggg
     6121 cctactagta atagctttca atgactttta catttccttg cgtagcattg tgttaatagc
     6181 agatgtgaac tatgtatctt taagtactga aagaaaatat ttcaatgacc taaggggttg
     6241 agatacccga ttctgtggct ggtagcacat tccctccgta tcccaatcct cgcttccaac
     6301 gccaagcttc gaaataaaca gcccatcagg atctagctta gctttgatgc ttgccaaacg
     6361 cttgtagact ttctctcccc aaaacacctc ctgataattc ttctcgtttg gatcacccaa
     6421 gttgcgataa gataccttga aactcggctg cattgagtac aagataggca tgtatttgtt
     6481 tgtaatctcc ttgagtgcta acttttttgc ctcaatagac ggctcgacag atcgtacata
     6541 ggtgaccagg tgtgcggatg atcgccaagc aggatgtatg gcggtgtcca agcctttatt
     6601 agcagcaatg cacccgccaa ggttgctagt gaataggagg tcatttgggc cgataggtag
     6661 ctttccaaat acctgagcca ccgtcaatgg gccttcagaa gagccaaata gttcgtttga
     6721 aatcatcatg gatgtctgca aagttccgat gcctctggga tggatatccg cgtccaagcg
     6781 aagctcagaa ttgatattgg ccacgaactt ggatgttaaa gtggtagaga tttgatcttc
     6841 gctaagtgat gcaatgtgtg gttggagtag tgtctcagca tgtaatacat tggtcatgtt
     6901 ggaaaagtgt aatgttaaac cggcgtttag gatgtctacg cttggacgag tgataattaa
     6961 ctgaccatgc acattctgct gattacagga tcgcaaaatg gataaaagcc tactaatggc
     7021 cttcacccag aatgatgtat ctgctcgcgt tgaagaaaga actagagtcg agacaaccgt
     7081 cggatcgtca gggaacgcac gaacagtcgc ctgagtgacg acaccaaagg tgcccccccc
     7141 tcctcctctg agagcccaga agagatcttg gttctggtgt tcgttggcaa tgaccagttc
     7201 tgcctaaaat actagtaagc atgggctctg aaaagaaacc gaacaggaaa tagacgtcat
     7261 acattagcag ttactacctg gtattccagt acattgtcca cggcaagccc tcttgtgaaa
     7321 ccagaccaag aagacacgcc gccgccctga aggaatccac caacgatacc aacggtggga
     7381 cactcacctc ccactacgct gtatttgtgg tcgataccgt gcttataaac ttccgagtgc
     7441 acgactccag ctcccagcgt gacggctggg cctgagcccg ttgcatcacc gtggacgaga
     7501 aagttgtcat catagtggat gtctttgaga aagtaggtgt gaatctgaag cgagtctggc
     7561 gcagctgacc gtcctgttgc atcatgccct gtgtttttaa tcaccaaacg gaggttatga
     7621 tccttcgcaa atctgataac gccctggaca tgggcggtcg atttcacggc ggccgagtac
     7681 aaaggcaatc tgccttggtg gcaaggaatc tcttgtggtc tctctgatga tgatactagc
     7741 aaacagctct cattatcacc agagccagtc tcccagatcc agtcttgtag ggtagctatc
     7801 atttgcgact ttcgtcagcc ctgtctctcc gaatcatctg tcactactcc gtagattagg
     7861 aaaacttacc tgggttagag gctcgccaac cgctgttacg actcaggtct agcacatctc
     7921 cacatgcaac agcatcataa tgtggatcgt gacacacgga gcccacaggc tgaacatgga
     7981 ctagattacc atcaattgaa gcattcaagc tagtccactg atgcgaatct ggccaacatg
     8041 gttcccatgg tctgcatcga caggagggag gatcttgcag cgatgacagg aatccccaac
     8101 tgaggaggaa gcccaccaca aaggttacaa agtggcgcat ttgacaattg gatattggta
     8161 aattcaccta aggtagaatt taaaggtatt aacttactca atcgtggggg aatatatgct
     8221 cattgcgacg gagacgtagg ggcgacatta agaaggcggt taaacttgac accggaggaa
     8281 tcctttggag cttgccaggc gccaagggtt cacaacctcg cattcggtca ctgtggtgac
     8341 caataatatg attggtaagg taggggtcga tgtgaatgaa tgataacgtt cgattcggtt
     8401 aaatcagagg tgcagacagc acctgacttt gtctaagaag gtacacagtg cgctacggta
     8461 atgaatagtc tacggaggta gttctacata atacattgta tccacccgtt gtcttagaga
     8521 gagtttcatc ctagtcaatg cgcgctgccc tcacataata tcctaagctt caagggagct
     8581 ctccctaaca gggataaatg gagaccatgg ctagctgcaa ctgccgtgac taccttgccc
     8641 tgcaagatca ctgcagaaac aatgcatatt attacgctag gtaataagta agtcaggcca
     8701 ctatcgtgcg ggctacatca cgtagcacta ggccacccta aataggcata gtgagatcgt
     8761 gatcgcgaat cttaatgcat aagtagctaa gatttaatta aaaaagcaag tagtattaat
     8821 aataacaaag ctactaatat tacatgtaga gccctagccc taaatctaac aaatcaaggc
     8881 cactaaatac cattaatagg cccacccgcc acgcctagcg ctttgcctaa ttggggtggc
     8941 ttagtgctac gtgatgtagc ccgcacgtta gtggcctaac ttacaggggt aactaaacgc
     9001 gcatctgtca aaagtaaatg cgactagtcc taattttttt ttgaaagcca ctaatgtatt
     9061 gtcttactaa gctttatatt tagaaaaaaa agcatagcta tatagactat ctataggtag
     9121 ggaactagta atacacatta gtaatacact cttacaatag ctttaataat attaatatta
     9181 atggatgcgt gtttagttgc caaagggcgg atacacagtt tgtgagattt gtaatccgta
     9241 tttagacagt aaagcggtta gcagaccaag ccagagtccg aacctcatat agaggagtac
     9301 ctatccacta cagtacatat tcactactaa attattcaga acgcaaaaca agtagtgagt
     9361 attttcaaac cgcatattca ttgtctgaac cacaggcgag acccgaagat atgcagtccc
     9421 aggtcaggtt gccatccaac ggcaatcctg ccctcagttt cccacagaat gaaatcggag
     9481 gccctgtgca ttggaagaca tatctcgaag gatgcagtcc ttgcagtttc ccatcactta
     9541 gaaccgtttg tcctagccag tcttggccgg cgtcagtatc aattacgatt ggggatagca
     9601 tttttagaag attggaacac ttctccgaca agaccgggat cagcgtggcc acggtattcc
     9661 gggcatcttg ggggcttgtc cttcgcatct ataccggaca ggattcagta tgtttcggcg
     9721 acatgacaac agccccaggc ggtatagatg ccattggatg tgttggtgtc tgccgggttg
     9781 agcttagcga cacggcagtg atttcgaaag tactccagag aatccaagcg gctagtgcga
     9841 ataagcttgc tattcctcat gttcccttat cagatgctgt gctgtccaag tgcatgccca
     9901 gtgcatcttt gttcaacaca tgcatgttaa tttcaggggg cggagaaagg ccagaaaaga
     9961 caagcagcac gtttgaaaaa gtagagcttg gctacgatga tcaagttagt gattccctag
    10021 cacattcaga gagcataaat tacaatgaac aataggaatg ctaacaacga ggcattagta
    10081 cgatattatc gtccgaggca gcgtagaaga cagtggagct agcgcagccc ttagctatcg
    10141 gacgtcattt ctatcagagg aacaagccac tagtattgca aatacatttg aacgagcggt
    10201 gtctgacctc attgggattg agaacaggat tggccaaata tgtttcctga gcgatctcga
    10261 caagtcacaa atatacacgt ggaacaaaga tccgcctctt cgtgctcatt cctgtgtaga
    10321 caccctcatc catgagcgtt gcctgtcaca gccaactgct tctgcggtga acgcgtggga
    10381 tggtgaactc agctatgaag agcttaacca tctctcctcg aaactctcgc ggcatctggt
    10441 aacgctaggc gtcggagcag aggtgtttgt acccctctgc tttgagaagt cgcgctggac
    10501 cactgtcgct atgcttgcgg tgatcaaggc tggcggagca ttcgtgctgc ttgacccttc
    10561 tcatcccgct gagcggctgc tcagtatttg ccaaaaagtg tcggcgaggc taatcgtggc
    10621 ttcagcacaa catgccaaat tggctgaaga tctagtgacc tccattgtcg aagttggaga
    10681 tgataaagcg gactggctca cagacaaagg tataaaagcg caaactcaaa cacggacacg
    10741 ccggtctgcg gcgccaggag acgctctcta cgcagtcttt acttccggtt caactggcac
    10801 cccaaagggg gtaatcatcg agcatgggtc gtttcacgct gccgtcttcc cgtataccga
    10861 agcagtcggc ctcaatcaag agtcgcgggt tttccagttc tcctcttatg cgttcgacgt
    10921 gacgattttc gatactctca tgactttgat cagcggtgga tgtgtgtgcg taccctcaaa
    10981 cactgagcgc tggagcgatg tggcaaatgc aatccagcgt tttcgggtca cccactcaag
    11041 tctcacgcca actgttgcac gaatcttgga ccccaaagat gtcctaactt tgagaacatt
    11101 ggtccttggt ggagagaagc tagtaaccag tgatattacc aagtgggtgg atcaagttcg
    11161 cctggttcat ctgtatggcg cgtccgagtg cccgatcatg tcgatccaat cgatgaccgg
    11221 agttgcatct gatttccaga ctacagatca tgcaactggt agtaactgtt ggattgtcga
    11281 tccaaacaac catgacagat tggtacccat cggtacaatc ggagaactgg tgatcgaagg
    11341 tactatcgtg ggccgtggct atctcgacga cccggaaaag tcatcggcca catttattcg
    11401 acctccgggc tggctgtgcc aagttcgagg cagtgggtac catagcgcag tatataaaag
    11461 cggtgatctt gtccaataca ctgcggatgg ctcgcttcga tatattgggc gtaaggacac
    11521 gcaggtcaag ctccgcggtc agcgggtcga acttggcgag gtcgaacacc acgtcaagct
    11581 gaccttcccc aacgcgacgg atgttgttgt ggagcttgtc gtcacgattc acgcctcgag
    11641 ctcgagggcc ccgattcttg tggctttcgt cctcattagc cacgaggcag atcccgatcc
    11701 ggagagcata cgaacaggtc gaggggaggg tttgagccag atattgagcg agcctaccga
    11761 tcggttttgt tcccagatcc ctatcgtaca gtcacaactt cagcaatcac tcccttctta
    11821 catggttcca gggattttcc tcccgttgat gacccttcca ctgaccagca cggacaagat
    11881 aaatcgcaag ctcttgcggg agcttgcagg ggcactatca agggaggaat tggaaagtta
    11941 tcagccgtca acaggtcctg ttcgtgcacc acagacgaca acggaaaagc tcttgcagca
    12001 atattttgct cgcgtgttga acatccctgt ggagcaggtc ggggccgatg accacttctt
    12061 tcaacgtggg ggagattctc tcacagctat gaagctagtg gcaatggccc gaaaggacaa
    12121 gcacaaactc actgttcagg acatttttga cagtcctcga ttgtctgcct tggcatgtgt
    12181 agtgagatct ggcaaggtcg atggcaacaa ggagccacct ctggaaccat tctctctggt
    12241 gaataaacat cgagacatta taagagccgc tgctcagcag tgccagcttc cagtccgggt
    12301 gattgaggat gtatacccct gtacaccact tcaacgaggc ttgatatctg agacgctgcg
    12361 agactctaag gcgtttatcg cccatctcgc cgtttcactg cctccggata tcgatctcca
    12421 gcgtctgcag gaggcatgga ccactgttgc gaacgctaac cccattttgc gcacgaggat
    12481 ggtgctatcc gcctcccatg gtctactgca ggttgtggtc cgggaggata tccgatggat
    12541 tgtatcgaag aatgctgaag cgcaggattt tttcgttggt gttggcaagc ccttggtgca
    12601 attagttctc tgctgtcatc gagaaggtaa tgaagttccg gtccagctgt tgctgatggt
    12661 ccaccatgcc gtttatgatg ggtatacttt gcccctgata tttgaacagg tcaaggcagc
    12721 atacaatgga ggcacccttg cgccaagacc agccgtccct ttcatccgct acgtacagtc
    12781 gattcccgat ggtacaggct actggaattc gttgatggcg aatcttcaga ctcctatctt
    12841 ccctgccctg ccttccaaat cgtaccagcc gttgcctaat gccattatga ggcatactat
    12901 catcacccca ggctcacata gacagtatac tcctagcact tatgtccggc tcgcatgggc
    12961 catcacgcag gcttaccacc aagggacctg tgatatcttt tttggaacgg tagtatctgg
    13021 caggaacgca ccagtcaccg acatcgagtt gatgactata ccgacagtcg ccacgatccc
    13081 atgcagagtc accttggatt ttcagagtct ggtgcaaagt gccctccgca agatccagga
    13141 cgacgctatt agcggcattc ccttcgagca acttggtctt cctcatatcc gtcgcctagg
    13201 agaacacgcc atgctggcat gttcctttca aaccttgctg tccatacagc cggctttgcc
    13261 tcccagtact gacgcatggt ttgagcagcc ggggtcgact attgattacc gggctaatgc
    13321 aacttacgcg atcaatctct tttttgggct tgaaggggat aagctaaaag cgacagcact
    13381 atatgatttc aatgtggtaa agaaagacaa aatgcaatcg atgcttgttg atttcggcaa
    13441 tatcttgcag acaatgcata agagccctaa tagcctgatt cgagatatcc ttgctgttcc
    13501 tcaacaaatg cgcggcccga tcaattcagc ctccttatag aacacctgcg cctcttgcgc
    13561 cgcttctgcg acatgacggt gagttttagg agtgaagagt atggtgctac gtacatgtat
    13621 gaacgtaatt agtacctaac aatactgatg agactttgta ggggctaaca gttgacctac
    13681 tttatcaatt ataatttaac ataccttgcc acattaccta gcgcgatcgg ctttcgatat
    13741 gctagatttg attatgaaca gaagggctag gataagcaac aagcgaaatc aagggggtga
    13801 tttaatctgg aataaaatac ctttgtaggt gttaagtgtc acgcgctacg cctgatgcgg
    13861 tggatcaaac tctcctaggc ctaggctaga gcttattaga attgtatgat ataacaactt
    13921 atattgcatg taaggtacaa gttacatatg tataggttat aagtagtaca agccctaata
    13981 tacactaata acacgccgcg ggcgacgagt gatgagtgtt tggtaggcta tgcgctatag
    14041 ggagctaata aaaatgcgtg cacactatgt aaccctagta ataactaata gggggttata
    14101 gttagtaaga gtaaggtata gtataagtat atataactaa ctaaagtaat atatactaat
    14161 aaaagctaat aaaaatatat atatactata taacctatat aataactaat aagaggttat
    14221 agttattatt ataagacccc ttaataagta tatataacta actaaagtaa tatatactta
    14281 taagagctaa taaatatata tatacactat atactaaggg taataactaa taggggatta
    14341 tagttattat tataaggcct tttaataagt gcccttaaat aagggtatat atataattat
    14401 agtaaggcct ttaataagta tatataacta acttaaggta tatatatata tatatatccc
    14461 ttattacctt agtaaaatta tcttatagat attttttccc tctcttaccc tagtaaatat
    14521 acctagttat attcccttta tattataaac taactatagc ctcttttacc ttttataatt
    14581 ccttttacaa aaccttataa tagttataat aagaagctta gtagctttac taataaatca
    14641 ctttcctagg atatatttat acctaataat ctatccttat ctaatataac taataagtaa
    14701 gtattagtaa aagaagcctt atatattaat tagttatata ttacttagtc tagtagtaat
    14761 attattaata aatatcttcc taataataaa tagtttaata ttactaaggc ttaagttatt
    14821 taagtcctaa cctttttaac atacctaact attaacctat taacctacat attctattat
    14881 atactagcac tacttactat agtaaataaa gtgtttaacc ctattaggta agctaaagaa
    14941 aagaggtata tagctaaata taatattact ataactactc tctttataaa aaagtgctat
    15001 attaataaag gctttttacc ttaactacac tatctttatt actatttaga tagtaagtaa
    15061 ctcttctaga ctagtaaata agaagtatag tgtagctata ctaagactta ttattacctt
    15121 atataagaat atataagaat aagaacctta aattaataag acctttttat aataatactt
    15181 taaaaagcaa aagatttata aagcctagta aaagggggtc ttagtgtagt gcattaggta
    15241 tataaactag tgtaccttac ccctttactt actaggggat atcttttgct aagttacttg
    15301 ctttatatat atgccttact tattccttat attaatactt atgagaacaa tagtagctag
    15361 gcaagaggta taggggctct agtatattaa ctaaagcttg ctaggtctaa gtgtgttata
    15421 cgtgcaagtc actagcttat agctagtggc ttactagtgt tacataaacc tagccctagg
    15481 atatagctta cctatagagt gtgctagtac acctatatta taggtattat tataagtaag
    15541 gccttataat taccccctta cttataacta ggctcctaaa tagcttacta gctattatat
    15601 agctatttac tacttagtta ctatattaaa ataataataa ataataagta atacttaagt
    15661 ataaatttac tagtaactct ctattatatt atatactttt cccttttata atactaaata
    15721 agttttctaa aaattattat tataccttta gttactttta ctttaccctt acttattact
    15781 atatttttat tataaagact aaatatattc ccttaaagga atattcctat atatattatt
    15841 tatatattaa atatatagac tttaagaaaa gctctttatt taagcctaaa ttaccctaga
    15901 ttaactatta attccttact aaattattta ctactattat aatagtaaag cattttaaat
    15961 actatattta gtgttataaa tatagtaata cctataatac tataagtata ctactattcc
    16021 ctagtctttt agtcccttat tactaatatc tttatataag taatagctac tataaaaggt
    16081 aactttttag accttttaga ccttttaaac taggtataaa ctcttataaa tacccttagt
    16141 aatattatta agaataacct taaggatagt atattctcta aggtaactta ctttagtatt
    16201 actaggtttt acttagcttt aatattaggt tttaactata ctcatatagt atattatatt
    16261 atatttagcc ttataagggt tactaaggtt tactaggttt atctttttct tacttatata
    16321 ctagtacttt acttatattt tagggtaaga ggtattaatt ttatataatt agtatattat
    16381 atcttagtaa taactttcta ttataatata gctagctttt attctagggg taataagtat
    16441 tttattcctt tttactactt atttactaac ccttttatag taaaactatt ataaactttt
    16501 ttatatttag aaaataaagg taactttata tttatagtct tataacctag gttttatacc
    16561 ctagggtata gtaaagcatt gctttttcta ggtataagag gaccttatta gtaaggataa
    16621 gaaagtaagt aaaatacctt ttttataaag gtatagttta ttcctatata aaggctacta
    16681 taaaggggtt ttctttaagt cttcttactt tataagcgtg ttttctttta ttttttagta
    16741 agtaatctaa ggtttctagt ctagagtata atagtagcta ataaggctat gccttttcta
    16801 taagaatatt atatcttttt acctataatt tacttatatt ttattacttt tcttactaga
    16861 cttactttag taaaatactt aaattatata ttaagtgctt tttatatcct ttactaaaac
    16921 ctattagtta tatttactta gctaatcctt ttattttact aggtatttat taatttctta
    16981 ggttttctta tagtccttaa tctccttaac tttatactta ttatctttat tctctaactc
    17041 tagtattagt atttccttat ctttagtgtt tttatagtaa ttttatagct ttaataagct
    17101 aatataaaat atattatata gttaactata ttttttaagt aatataagtc tatatgctta
    17161 tttacttata gtattaagta cttaaaatag tctaataaat ctaggggtta gcttttattt
    17221 tatatcctta agcctaatat tctttactaa tagtaatact aggttacctt tttttagtat
    17281 taatagctag taatactagt tatagtactt tatttaagtc ttagtaactt ttacttagtt
    17341 ttactttagt tactctttaa ctttatatag ctttataata tatatatagg cttttagtac
    17401 ttccctttct ttagtcttat ccctaaaagc taggtaactc ttaggtaaat agcctataag
    17461 ggagtaatta agaaagtagc ttatagtctt atttactata ttattataag taaattaagc
    17521 tattagaagt agcttaggct atatttatta gttattagct ataaagcatt aaaggtaata
    17581 cttaagtact tagtttattc tctttattta cctattagtt tagaggtaaa acactataaa
    17641 aagcctttac tttatatata ataatatagt taaatactaa cctacttata cctagttact
    17701 aaaagtaata ctttaatagc ttaagagtat atttagtcct aaagtaactt actagtaaat
    17761 tattatagta tagctataaa agctcttatt ataagatagg ctcctaggga ataactacct
    17821 agtcttagta tattaggaga ccccttatgc tatataacta taaactagct tttctcttat
    17881 ctcttactaa ggaattatta atcttactat tttacctcta tagatttaaa tcttaattct
    17941 atacctttta tagtaattat actaatagtt tatttagcct agattagtaa ggatttagta
    18001 gtataatagt ctcttatatc tcttatatta cactaatatc ttaaatatat attactttct
    18061 cctagaaatt acccttattt agctaatctt ttacttaatt tatagtagat aactagcctc
    18121 ttaactaggt tactttagcc tttagagctc tctttatagt aactagggta ttttcctccc
    18181 ctaaaggtat tttaataagc ctctttacta agactagggt attttcctcc cttaaaggta
    18241 tcttactata ttttctttaa tatattaaga ctagggtatt ttccttcttt aaaggtatct
    18301 tactatattt tctcttatat attagtatct tttcttttac tagttcttta gtaattacta
    18361 ttttctttta aagttctagt aaaagtgcct tatttattag gggtttacct ttataattag
    18421 attatcttaa tagtatattt actaggttac ttttcctagg tttatgccta attataaagt
    18481 aaaaggggca gagaaatata cactatttaa cttacctttt atttagcttt tactacctta
    18541 taaaagtcta taagttatag taatctaata ggacctttac tagggttact atacctttaa
    18601 tatagtaagt agcttctaat ttactatact ataattatat ttagtgtttg taaacttcct
    18661 taactaaaat actataggat attattagct cttattatcc tattaagata aaattcctac
    18721 tattataaag actaaagtat ctatcttaat gcacactagc taacttaggt tataataata
    18781 aagaaaaggt acttattaaa aggtatcttt tagctagtta aatactagct attccctttc
    18841 cttaaatata aacttcctag tttaaatact attttaatta ccttttatta gtgtatataa
    18901 gggtactata atcctagagt attagtaaat aaacctttag taaaagttgt agaattctag
    18961 gaaagactat atatctttaa agcttatagg ctccttttag tcttagatta tattaactct
    19021 atatatatct attaaaatac tattaactaa ttaaataagc cctaggaatt ttactaattc
    19081 ctagtaaaat aaatacttta agggtttcat atatagcttt actaacctta tatattctaa
    19141 aactttctta atatatatag tatacttctc ttatattttt aagaaaataa ggattctatc
    19201 tagatatact atataaatag tatttactag cttataaagt gctttataaa tatagcttta
    19261 aaaagtagct agggtattag ttagcttaaa gggtattata agatatttat agtgtttata
    19321 ataggtataa aatatagtct tttacttatt actctcttta atatagattt aatagtaag
//
