LOCUS       BGC0000352             26231 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Acinetobacter sp. ADP1 complete genome.
ACCESSION   BGC0000352
VERSION     BGC0000352
KEYWORDS    .
SOURCE      Acinetobacter baylyi ADP1
  ORGANISM  Acinetobacter baylyi ADP1
            Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter.
COMMENT     Annotation data relative to COG assignations, enzymatic function
            prediction (PRIAM software), TMHMM and SignalP predictions, and
            synteny results (Syntonizer software) are available via the MaGe
            annotation system
            (http://www.genoscope.cns.fr/agc/mage/acinetoscope). See this web
            site
            (http://www.genoscope.cns.fr/externe/English/Projets/Projet_DY) for
            more information on the overall project.
            Each annotation includes a confidence level as follow: 1  :
            Function experimentally demonstrated in the studied organism 2a :
            Function of homologous gene experimentally demonstrated in an other
            organism
            2b : Function of strongly homologous gene
            3  : Function proposed based on presence of conserved amino acid
            motif,
            structural feature or limited homolgy
            4  : Homologs of previously reported genes of unknown function 5  :
            No homology to any previously reported sequences 6  : Doubtful CDS
            7  : Gene remnant
            Classification of gene products by their type and by their cellular
            role(s) was made with the MultiFun system
            (http://genprotec.mbl.edu/).
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:35:52
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1341)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2761"
                     /db_xref="EnsemblGenomes-Tr:CAG69505"
                     /db_xref="GOA:Q6F8W0"
                     /db_xref="InterPro:IPR002528"
                     /db_xref="UniProtKB/TrEMBL:Q6F8W0"
                     /function="4.2.A.7 : The Drug/Metabolite Transporter (DMT)
                     Superfamily"
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 300.2; E-value: 3.7e-91)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2761"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pt : putative transporter"
                     /product="putative multidrug resistance pump"
                     /protein_id="CAG69505.1"
                     /transl_table=11
                     /translation="MNILKDILFPILKLALPLILIQICQASLGVINTMVAGRYYYIDLA
                     GIGLGSNMWTPVFILFTGILYVLVPKISAMQQHSSQEIGVLIQQGKRVAFLLSIFGFIL
                     IQLLAFLCPWLIGDQQVAQIAKQYLHFVAFGVPGLVYMTLFRFVSEGHSLLKPIILTYA
                     ILLVCDASLCLVLVNGIGFIPEMGGAGTGLATAMSAYIACFCMYQFVSKAIPELKIKRI
                     QVGFKESLGLLKQGLPIGITLILQILALATLAFFASQLGAKAIAAHQIVINIAMLIIMI
                     PIAISSATTIRIAYFSATNHHQGKISTSLCVVVLTLIYSFLMAGILIGFAQHIVSLFTQ
                     DAEVLNVAVGLMSYVAIFLIFDAIQTVASGVLRGLHQFMQPLFIILFCYWFVIIPLSYL
                     MGVQGWLQVRANVDVIWIVLTCGISLAAVLLTIQSYCHVTGIMNKRS"
     protocluster    1..26231
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[16074:19320]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16075..19320
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..26231
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..26231
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000352"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..26231
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1341)
                     /locus_tag="ACIAD2761"
     gene            complement(1381..2532)
                     /locus_tag="ACIAD2762"
     CDS             complement(1381..2532)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2762"
                     /db_xref="EnsemblGenomes-Tr:CAG69506"
                     /db_xref="InterPro:IPR007037"
                     /db_xref="InterPro:IPR019595"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V9"
                     /gene_functions="other (smcogs) SMCOG1200:vibriobactin
                     utilization protein ViuB (Score: 64.9; E-value: 9.3e-20)"
                     /gene_kind="other"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2762"
                     /note="Evidence 5 : No homology to any previously reported
                     sequences"
                     /product="hypothetical protein; putative
                     siderophore-interacting protein"
                     /protein_id="CAG69506.1"
                     /transl_table=11
                     /translation="MFYLRNLGGFMKHFTTIKDQDRKLDIMDHVNQDHHKELLIIAQTY
                     GKNNAIDDAVIVDIYEEGILLHTQDPFSVAKQDLFIQFELKGDLEEQILYLAYNSFAKQ
                     KIEFSNNAKQFFEVIEKSQVSQNITRLTIKSQIALPQYYAGYAYGFILKVLEKAPEINI
                     SSSNKSSVLKNIVDRGFLWVMKHLSAQKRQKLMENMNKDIRLYTLRQSFGHEGQDALNY
                     GYVDIFTHGNSLGSQWVQQLNVGSLISSRTETDDKHDHLQNGAAVLIADETAYPALAGI
                     LDFWSNPHPPLVILLCANESDLDYFKNYDFPENSIIKNIVGSLENQSIEIIEILNEFEH
                     LDNVWGALENNVAKKIRHYFRNERKLQGKNNHIKGYWRLQKAH"
     gene            complement(2559..3782)
                     /locus_tag="ACIAD2763"
     CDS             complement(2559..3782)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2763"
                     /db_xref="EnsemblGenomes-Tr:CAG69507"
                     /db_xref="GOA:Q6F8V8"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V8"
                     /function="4.2.A.1 : The Major Facilitator Superfamily
                     (MFS)"
                     /gene_functions="transport (smcogs) SMCOG1131:major
                     facilitator transporter (Score: 370.7; E-value: 1.1e-112)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2763"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pt : putative transporter"
                     /product="putative transport protein (MFS superfamily)"
                     /protein_id="CAG69507.1"
                     /transl_table=11
                     /translation="MSHHSKPWLLLISTYTTQYIGIAFMMSATFAILRQHGIALDKLAL
                     LNLIALPMLGKILYAPFVDSFRLFTQGQYRSWLLFAQLCMTGLLLVCGYLEVNKQFPIM
                     LVLFIVYSLFMSIQDVAIDGLATKIFEASERQFANSIQYASNLLGNIIGGGLLLILYPW
                     LQWKGAFIILALLTAITWIQLLFYREPENEFSNPHHNLSSQFKSLAQQLKLFITKHKSW
                     FVLLFIYPIGFTAVFGILNPLLVDAKWSLVDIGFATKVFGSIIGILSAFLATLLINQLQ
                     RKKALITLTVMQGLTLLLFIPLTLGYTSKLIVYLAIFGYFIANPGLIATLSTLIMDRAA
                     SMPAKATFFSLQLSLVVFMGFVYSALGLTLAQHIGYTAVVILTFICALGVAALSWKLLS
                     PDDPNVPT"
     gene            complement(3818..5965)
                     /locus_tag="ACIAD2764"
     CDS             complement(3818..5965)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2764"
                     /db_xref="EnsemblGenomes-Tr:CAG69508"
                     /db_xref="GOA:Q6F8V7"
                     /db_xref="InterPro:IPR000531"
                     /db_xref="InterPro:IPR010105"
                     /db_xref="InterPro:IPR012910"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V7"
                     /function="5.5.7 : Fe aquisition"
                     /gene_functions="transport (smcogs)
                     SMCOG1051:TonB-dependent siderophore receptor (Score:
                     481.2; E-value: 9.4e-146)"
                     /gene_kind="transport"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2764"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type prc : putative receptor"
                     /product="putative ferric siderophore receptor protein"
                     /protein_id="CAG69508.1"
                     /transl_table=11
                     /translation="MNTSIHFKKAILSISITLLLTQNIFAGENTQSAQQLPTIIVKAEA
                     TDNTTLSNGQVTKKSQVGMLGDKDTMDIPFNVTSYTAQYIQDQQVTSIAKALKNEPSVR
                     SVFSGNGLGEYFNIRGFYTQSHEMAWNGLFGLVPHNRIPTEFLERVEVFRGTSALLNGM
                     SLGGAVGGVINVVPKRAGEQDLTRVTATYTSDSNLGLHLDVGRRFGDEKQFGIRVNALK
                     SGGDTVLDGQEEDRALGSIALDYKGDRLRASLDLYDINEKVDGGMPLMVSFASADIPKA
                     PDSKINTQPGSYAHTKAKGLIANVQYDFLNDWTAYATVGTKKQKSHGVIANNALGMAAQ
                     PNGDYTAISRMNANDTDVNAVETGVRGTFTTGQIKHQLVLSGNTIDQNTYMGLSVGSPW
                     QSNIYNPKPGTNAVRPANVPKISETKLSSVALADTLSVLQDKYQLILGLREQRVESQSF
                     SINPATNALNPAYKESALTPAVGVVLKPWGNHLSLYANYIEGLSQGDTVSDTTAANVNT
                     VFKPYKSKQFEIGTKWDLGNFRNTLSFYQITKPSLIKNTTTNIYSDDGEQRNRGVEWTT
                     VGDLVDHLRLLGGVSYLDAKYTKTAGGVYQGNDVMGIPHWQSNLGVEWDLPVQPNLTLT
                     ANSVYTGSMYADNANTQKLPDWIIFDLGARYATVIAQRNVVFRGGIDNVFDKKHWAGVW
                     NGYVGVGGDPRTYKLSMQIDF"
     gene            6216..6956
                     /locus_tag="ACIAD2765"
     CDS             6216..6956
                     /NRPS_PKS="Domain: Thioesterase (7-230). E-value: 1.9e-26.
                     Score: 85.7. Matches aSDomain:
                     nrpspksdomains_ACIAD2765_Thioesterase.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2765"
                     /db_xref="EnsemblGenomes-Tr:CAG69509"
                     /db_xref="GOA:Q6F8V6"
                     /db_xref="InterPro:IPR001031"
                     /db_xref="InterPro:IPR012223"
                     /db_xref="InterPro:IPR029058"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 160.4; E-value: 6.7e-49)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2765"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative thioesterase"
                     /protein_id="CAG69509.1"
                     /transl_table=11
                     /translation="MNNNSKINLFCVPSAGSSASIFSAWDKTSAENLKVIALEYPGHGR
                     KIQQSLSHDPDFLAHQFSLEILAYGNTPYVLFGHSVGASLIWKIEEKLKLLHADHNLIL
                     KIVSARPSPLFQNLIHNYSHLTDEQMIKELRLYNNFPDEILNNASALNFFLPIIKNDFI
                     LSDNMLKKPIFKSSVPLMSVYGEADPYIKNHNIMESWSTYTNKWLGAHQFSGDHFYFLD
                     TTILQKMLHLIQEKIYLLMKTTLV"
     aSDomain        6237..6905
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2765_Thioesterase.1"
                     /evalue="1.90E-26"
                     /label="ACIAD2765_Thioesterase.1"
                     /locus_tag="ACIAD2765"
                     /protein_end="230"
                     /protein_start="7"
                     /score="85.7"
                     /tool="antismash"
                     /translation="NLFCVPSAGSSASIFSAWDKTSAENLKVIALEYPGHGRKIQQSLS
                     HDPDFLAHQFSLEILAYGNTPYVLFGHSVGASLIWKIEEKLKLLHADHNLILKIVSARP
                     SPLFQNLIHNYSHLTDEQMIKELRLYNNFPDEILNNASALNFFLPIIKNDFILSDNMLK
                     KPIFKSSVPLMSVYGEADPYIKNHNIMESWSTYTNKWLGAHQFSGDHFYFLDTTILQKM
                     L"
     CDS_motif       6432..6467
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2765_0001"
                     /evalue="7.70E-04"
                     /label="NRPS-te1"
                     /locus_tag="ACIAD2765"
                     /protein_end="84"
                     /protein_start="72"
                     /score="12.1"
                     /tool="antismash"
                     /translation="PYVLFGHSVGAS"
     gene            6981..7808
                     /gene="entD"
                     /locus_tag="ACIAD2766"
     CDS             6981..7808
                     /EC_number="2.7.8.-"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2766"
                     /db_xref="EnsemblGenomes-Tr:CAG69510"
                     /db_xref="GOA:Q6F8V5"
                     /db_xref="InterPro:IPR008278"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V5"
                     /function="5.5.7 : Fe aquisition"
                     /gene="entD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060:4'-phosphopantetheinyl transferase (Score: 167.6;
                     E-value: 4.5e-51)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2766"
                     /note="Evidence 2a : Function of homologous gene
                     experimentally demonstrated in an other organism; Product
                     type e : enzyme"
                     /product="phosphopantetheinyl transferase component of
                     siderophore synthetase"
                     /protein_id="CAG69510.1"
                     /transl_table=11
                     /translation="MFNQEYKQTPLNSEQYLELKFSNIDFEHSILKTPKIIIHQINLLD
                     IDAQKIYNLYNKYNIFLPKHVTKASIKRKCEFFLGRLAAKYALNDLGNYSSFIIERGKQ
                     GEPLWPDQITGSISHSMLDCTQGIAIAATSRLSKNMNDLKELSKIYNQTASLSGQFLGI
                     DIEIKKNSEIFDRNPSILTNIFSSQEIKLISPFLKQRPVLHLIIFSAKESLIKVVYNKY
                     KKIISFDTMHCINICEQTQTFMFYIPQISNNEKFLVNYIELDYQILTYCCLKS"
     gene            complement(8011..8598)
                     /locus_tag="ACIAD2767"
     CDS             complement(8011..8598)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2767"
                     /db_xref="EnsemblGenomes-Tr:CAG69511"
                     /db_xref="GOA:Q6F8V4"
                     /db_xref="InterPro:IPR016181"
                     /db_xref="InterPro:IPR019432"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V4"
                     /function="5.5.7 : Fe aquisition"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     178.1; E-value: 5.9e-54)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2767"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative siderophore biosynthesis protein;
                     putative acetyltransferase"
                     /protein_id="CAG69511.1"
                     /transl_table=11
                     /translation="MPGFFDYAEHQVSYTLRDVVLPQDLPLLVKWMHQPHIIPQWQLNK
                     SELELAVYFERMLCDDHQHLYIIQIDRKDVGYLEIYEAKRDRLALYYDAEENDLGWHVL
                     LSEDAVGKGHFRAVMRMLSFLIFEHSKAGKVVGEPDETMLVYEKIKQDIALNEQGKIKL
                     QEKTAVLYHCFREQFYRQCGHYYEEFKRKKAS"
     gene            complement(8703..9863)
                     /locus_tag="ACIAD2768"
     CDS             complement(8703..9863)
                     /EC_number="4.1.1.17"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2768"
                     /db_xref="EnsemblGenomes-Tr:CAG69512"
                     /db_xref="GOA:Q6F8V3"
                     /db_xref="InterPro:IPR000183"
                     /db_xref="InterPro:IPR002433"
                     /db_xref="InterPro:IPR009006"
                     /db_xref="InterPro:IPR022643"
                     /db_xref="InterPro:IPR022644"
                     /db_xref="InterPro:IPR022653"
                     /db_xref="InterPro:IPR022657"
                     /db_xref="InterPro:IPR029066"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 329.2;
                     E-value: 4.2e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2768"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative ornithine decarboxylase"
                     /protein_id="CAG69512.1"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 5.5e-15,
                     bitscore: 45.7, seeds: 500, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 9.1e-51, bitscore:
                     162.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPLYFQSNMKDHLEDLVRTKDTPFLVLDLSVIEKHYLELKQGF
                     PNTDIYYALKANPANEVIDRLNSLGSNFDLASVNELKKVQAFGVDASRLAFGNTIKKRI
                     DIQYFYDQGVRLYVTDSDIDLNNIAHYAPGSKVFFRLSIDGSETADWPLSGKFGCNAEC
                     VIRLAIKAKELGLIPYGISFHVGSQQRKIDLWDSALQETKAIFDVLATEHNIRLKMLNL
                     GGGLPAQYVQETEAFDNYSKQINAALEIFKSYHLEQIILEPGRSLVGNAGILVSEIVLI
                     SQRPQSGTKRWVYTDVGVFNGLIETLGESIQYPIMCKKTGNSDDIILAGPTCDSMDIMY
                     QNKKYELPLSLEIGDHLYWLSTGAYTTSYSSIEFNGFPPLQYYALN"
     gene            complement(9873..11213)
                     /locus_tag="ACIAD2769"
     CDS             complement(9873..11213)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2769"
                     /db_xref="EnsemblGenomes-Tr:CAG69513"
                     /db_xref="GOA:Q6F8V2"
                     /db_xref="InterPro:IPR025700"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V2"
                     /function="5.5.7 : Fe aquisition"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 398.1;
                     E-value: 6.7e-121)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2769"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative siderophore biosynthesis protein;
                     putative Lysine/ornithine N-monooxygenase"
                     /protein_id="CAG69513.1"
                     /transl_table=11
                     /translation="MSTQQIYDIVGVGVGPFNLGLACLTAPLSELKTIFFDPKEEFDWH
                     SGIMPEGSTLQIPFIADLVSFADPKSHYSFLNYLKLNNKLYQFFIRENFFILRAEYNLY
                     CKWVTSQLENVHFKSFVDEIDYDEVGELYTVTVKQPQGEITVITKNLVLGTGTTPVMPK
                     FCQGYSDNVHSSADYLKYKKDYLNKKSITIVGGGQSGAEIYYDLLSEIDQHEYQLNWLT
                     KAPHFFSMDLGKLTLEYTSPDYTSHFHSLEQNKRDQVIGSQSALYKGIELSFVNRIYDL
                     LYQKSLYAPIATRMMPNCALEMVTQQDSHLDLIFKNSDINKSFKLHSEVLILALGYEYN
                     IPECLTPIRSQINWDNKNRIQVNWNYSINDKNTIFAQNIGIYSHGFTVPDLGMGCYRNA
                     IIINSILGREVYPVEKRIAYQEFAPLEDEIVTTLKTKPKPQHTKLYF"
     gene            complement(11227..12846)
                     /gene="entE"
                     /locus_tag="ACIAD2770"
     CDS             complement(11227..12846)
                     /EC_number="2.7.7.58"
                     /NRPS_PKS="Domain: AMP-binding (39-446). E-value: 5.1e-73.
                     Score: 237.8. Matches aSDomain:
                     nrpspksdomains_ACIAD2770_AMP-binding.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2770"
                     /db_xref="EnsemblGenomes-Tr:CAG69514"
                     /db_xref="GOA:Q6F8V1"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V1"
                     /function="1.5.3 : cofactor, small molecule carrier"
                     /gene="entE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     345.5; E-value: 7.1e-105)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2770"
                     /note="Evidence 2a : Function of homologous gene
                     experimentally demonstrated in an other organism; Product
                     type e : enzyme"
                     /product="2,3-dihydroxybenzoate-AMP ligase"
                     /protein_id="CAG69514.1"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-82, bitscore:
                     266.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFLEQDIQQGYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFG
                     DCIAAIQDQKQLTYKQLYDYAIRYGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAI
                     GARPVFCLHGHGAYEIENIARQSRAVGFIKLCGTANEITAVDVCEEFSVPNFQLWFRET
                     ILSQETIAGSLPQLKHLNLDTNIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSI
                     EKSVEVAGLNPQTKQLVVLPVMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQK
                     YKIEQVSLVPAIATLWLNAESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQV
                     YGMAEGLVNFTHLDDTNAVTIQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYT
                     INGYYNLHEINRRSFTDDGFYKTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEE
                     FILQYPTVKDVCVIGVSDEHLGERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPD
                     EIDVVADFKYTHVGKVNRQKLG"
     aSDomain        complement(11509..12729)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2770_AMP-binding.1"
                     /evalue="5.10E-73"
                     /label="ACIAD2770_AMP-binding.1"
                     /locus_tag="ACIAD2770"
                     /protein_end="446"
                     /protein_start="39"
                     /score="237.8"
                     /specificity="consensus: dhb"
                     /tool="antismash"
                     /translation="SVSRFGDCIAAIQDQKQLTYKQLYDYAIRYGAYLKHKGIRETDFV
                     LLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAVGFIKLCGTANEIT
                     AVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNLDTNIQALSSSEDIAFLQLSG
                     GTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVMHNFCMSSPGFLGVFYAG
                     GTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESLKDYDLSSLKVIQVGGAK
                     LLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQTQGKKLSHLDEIRITDH
                     HGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGDIGYLDDDLNIVVTG
                     REKEQINR"
     gene            complement(12859..16059)
                     /locus_tag="ACIAD2771"
     CDS             complement(12859..16059)
                     /NRPS_PKS="Domain: Condensation_LCL (49-329). E-value:
                     5.9e-25. Score: 79.7. Matches aSDomain:
                     nrpspksdomains_ACIAD2771_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PCP (517-581). E-value: 1e-16. Score:
                     52.7. Matches aSDomain: nrpspksdomains_ACIAD2771_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (616-898). E-value:
                     6.5e-54. Score: 174.8. Matches aSDomain:
                     nrpspksdomains_ACIAD2771_Condensation_LCL.2"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2771"
                     /db_xref="EnsemblGenomes-Tr:CAG69515"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="UniProtKB/TrEMBL:Q6F8V0"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     185; E-value: 4.7e-56)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2771"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative nonribosomal peptide synthetase with
                     phosphopantetheine-binding domain"
                     /protein_id="CAG69515.1"
                     /sec_met_domain="Condensation (E-value: 3.2e-38, bitscore:
                     121.6, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.8e-14, bitscore:
                     42.4, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQPSIMSDDLLSLFESKLQDIGLSERISTEAVEHYTENQIINI
                     EKNGVQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLN
                     LRYDLDDEGILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQKPINLAKAPAIQFTLL
                     PQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELSSKIPAKVL
                     VNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRCSSSIP
                     LKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSN
                     ILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVHNISIEQILSATKTKRNTIPN
                     VLVTQFIDGSQFLKLEQVETSTLIIPPIHSDYDLTLAFQIKADEIHFELTTGEKLSKKI
                     GLLLLEQWIEFLHLDAQQRLEEAAIFAFGHQASPYGSDQEHWAQPTSSVQPQVDASITQ
                     LILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALE
                     LSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETV
                     NEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ
                     QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYT
                     SRVDGKAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDM
                     PPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKV
                     LSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPF
                     AIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGL
                     HFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESFIHIDTQSEECTQID
                     VMEIRHQLSTIQLPELAI"
     aSDomain        complement(13366..14211)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2771_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.50E-54"
                     /label="ACIAD2771_Condensation_LCL.2"
                     /locus_tag="ACIAD2771"
                     /protein_end="898"
                     /protein_start="616"
                     /score="174.8"
                     /tool="antismash"
                     /translation="QGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQA
                     DQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKD
                     EQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDD
                     SALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQ
                     LYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVM
                     H"
     CDS_motif       complement(13372..13443)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2771_0005"
                     /evalue="7.30E-04"
                     /label="C5_LCL_267-296"
                     /locus_tag="ACIAD2771"
                     /protein_end="896"
                     /protein_start="872"
                     /score="12.1"
                     /tool="antismash"
                     /translation="SGTSVACRQDPNYQDTLGYFTNVV"
     CDS_motif       complement(13804..13863)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2771_0004"
                     /evalue="8.40E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ACIAD2771"
                     /protein_end="752"
                     /protein_start="732"
                     /score="27.9"
                     /tool="antismash"
                     /translation="HIAMDEWSSGILMRELIQAY"
     CDS_motif       complement(14083..14199)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2771_0003"
                     /evalue="3.00E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ACIAD2771"
                     /protein_end="659"
                     /protein_start="620"
                     /score="22.8"
                     /tool="antismash"
                     /translation="AMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFV"
     aSDomain        complement(14317..14508)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2771_PCP.1"
                     /evalue="1.00E-16"
                     /label="ACIAD2771_PCP.1"
                     /locus_tag="ACIAD2771"
                     /protein_end="581"
                     /protein_start="517"
                     /score="52.7"
                     /tool="antismash"
                     /translation="LILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLL
                     IKIADFFNAPTALELSQCV"
     aSModule        14317..15912
                     /domains="nrpspksdomains_ACIAD2771_Condensation_LCL.1"
                     /domains="nrpspksdomains_ACIAD2771_PCP.1"
                     /incomplete
                     /locus_tags="ACIAD2771"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(15073..15912)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2771_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="5.90E-25"
                     /label="ACIAD2771_Condensation_LCL.1"
                     /locus_tag="ACIAD2771"
                     /protein_end="329"
                     /protein_start="49"
                     /score="79.7"
                     /tool="antismash"
                     /translation="VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQ
                     KLYEGDSNLNLRYDLDDEGILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQKPINLA
                     KAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIE
                     LSSKIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQ
                     KAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEA"
     CDS_motif       complement(15469..15531)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2771_0002"
                     /evalue="4.70E-02"
                     /label="C3_LCL_132-143"
                     /locus_tag="ACIAD2771"
                     /protein_end="197"
                     /protein_start="176"
                     /score="6.6"
                     /tool="antismash"
                     /translation="HHILLDDSAWQPIFAQLSQNY"
     CDS_motif       complement(15769..15834)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2771_0001"
                     /evalue="2.00E-02"
                     /label="C2_LCL_024-062"
                     /locus_tag="ACIAD2771"
                     /protein_end="97"
                     /protein_start="75"
                     /score="7.3"
                     /tool="antismash"
                     /translation="LAFRLSGEIEISRLSNAIQKLY"
     gene            complement(16075..19320)
                     /locus_tag="ACIAD2772"
     CDS             complement(16075..19320)
                     /NRPS_PKS="Domain: Heterocyclization (4-292). E-value:
                     1.4e-36. Score: 118.2. Matches aSDomain:
                     nrpspksdomains_ACIAD2772_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (459-859). E-value: 1.9e-82.
                     Score: 268.9. Matches aSDomain:
                     nrpspksdomains_ACIAD2772_AMP-binding.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2772"
                     /db_xref="EnsemblGenomes-Tr:CAG69516"
                     /db_xref="GOA:Q6F8U9"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR013624"
                     /db_xref="InterPro:IPR020845"
                     /db_xref="InterPro:IPR025110"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U9"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     94; E-value: 2e-28)"
                     /gene_kind="biosynthetic"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2772"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative non-ribosomal peptide synthetase with
                     condensation, AMP-binding and phosphopantetheine-binding
                     domains"
                     /protein_id="CAG69516.1"
                     /sec_met_domain="Condensation (E-value: 2.9e-29, bitscore:
                     92.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.3e-90, bitscore:
                     293.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINQMPLTPMQKAYLLGKSKMFPLSQSSMHDFRELHGKIDAEIFS
                     QRLTILVKHYSALRTMIDETRLVQYVVPKIELTNQLKIYDFRQLNISEAVRRLDLLREE
                     YRYFLHDLAISPWQIALIQLPEKAEVSSVVLTSFDGLIIDGYSISVLLDQLFDFTRDLN
                     NLLSSEEKKSNTDDIDFFNATEKDRQFWHEKLSQVDEVSQLPWANTLETITHPHYGRRS
                     VVLAKSQFDQLSKLAAQYKVFPNALLTTLILDVLSRWTEEQKLLISMPVSHSALHKTVG
                     NSSSFIVLDYQYSPEMSLVDQIKSTQKQILECMGHTSYSGIELSKYLMRTLKESIVLPV
                     ALTNGLSWVKPPQHDHIRYAVGQTQTPQLALDIRLSLSAQSELVIDLDFVEEALSETMI
                     QDLADALLARLNDLTKLNGELQQPKHICNIAVLSDDADISDDYQHVEVVDYLANIQCHL
                     FEKIPNKTALIYDGKKVTYAELGAHVAKVRRALDLAQIGQNQVVAICLRKSPEHIYTIL
                     ACALSGIVWLPVDMDSPKLRQQYILKNSRADLAISTSPIEGLLTLNIDEILKVSSNSNL
                     YSGSAESKFESELSWHHHYDASPAYYLYTSGSTGTPKCVVLNNRATAHVLQETIDFWGI
                     NDKDIHLAATPFHHDMSIFDLMAPLSVGGTLVVPTLEEAKSAVAWAELIERYQVSIWCT
                     VPAMVDMLLTSAEPSQLQSIRLINQGGDYVKPSVVQKLREILPNTRLISIGGPTETTIW
                     SIWHEITSEDIDVIPYGKEMVHNRYYILNKFGEFCPPGVVGQLYMSGINLANGYLLDGK
                     LTQKDFVLLTLPNGEIHRVFRMSDKGYLREDGNIIFAGRDEGYLKVRGVRIAASEIENA
                     LLKHAKITDCVVITCTNPVYEGNELVAIYKTDHADLNSMRPSELRQFLQDYVPNSHIPS
                     RWVPLAEFPITRNGKIDRKTLKQVAHDFLYQTYAKATNDHPNFRAVKEVQDTAHGTQQT
                     SKATGFTQTAQQPSIAKDVIHHLQMSLANHTGQADLFLDTEILALGISSGHLNRLAKHF
                     SQQLNTSIQFSDLAKCKTIGDIVMNIESQLHQK"
     CDS_motif       complement(16714..16779)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2772_0005"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ACIAD2772"
                     /protein_end="869"
                     /protein_start="847"
                     /score="10.5"
                     /tool="antismash"
                     /translation="FAGRDEGYLKVRGVRIAASEIE"
     aSDomain        complement(16744..17943)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2772_AMP-binding.1"
                     /evalue="1.90E-82"
                     /label="ACIAD2772_AMP-binding.1"
                     /locus_tag="ACIAD2772"
                     /protein_end="859"
                     /protein_start="459"
                     /score="268.9"
                     /specificity="consensus: thr"
                     /tool="antismash"
                     /translation="EKIPNKTALIYDGKKVTYAELGAHVAKVRRALDLAQIGQNQVVAI
                     CLRKSPEHIYTILACALSGIVWLPVDMDSPKLRQQYILKNSRADLAISTSPIEGLLTLN
                     IDEILKVSSNSNLYSGSAESKFESELSWHHHYDASPAYYLYTSGSTGTPKCVVLNNRAT
                     AHVLQETIDFWGINDKDIHLAATPFHHDMSIFDLMAPLSVGGTLVVPTLEEAKSAVAWA
                     ELIERYQVSIWCTVPAMVDMLLTSAEPSQLQSIRLINQGGDYVKPSVVQKLREILPNTR
                     LISIGGPTETTIWSIWHEITSEDIDVIPYGKEMVHNRYYILNKFGEFCPPGVVGQLYMS
                     GINLANGYLLDGKLTQKDFVLLTLPNGEIHRVFRMSDKGYLREDGNIIFAGRDEGYLKV
                     R"
     aSModule        16744..19308
                     /domains="nrpspksdomains_ACIAD2772_Heterocyclization.1"
                     /domains="nrpspksdomains_ACIAD2772_AMP-binding.1"
                     /incomplete
                     /locus_tags="ACIAD2772"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(16867..16956)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2772_0004"
                     /evalue="1.10E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ACIAD2772"
                     /protein_end="818"
                     /protein_start="788"
                     /score="27.4"
                     /tool="antismash"
                     /translation="PPGVVGQLYMSGINLANGYLLDGKLTQKDF"
     CDS_motif       complement(17470..17523)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2772_0003"
                     /evalue="1.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ACIAD2772"
                     /protein_end="617"
                     /protein_start="599"
                     /score="24.0"
                     /tool="antismash"
                     /translation="AYYLYTSGSTGTPKCVVL"
     CDS_motif       complement(18067..18102)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2772_0002"
                     /evalue="3.70E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ACIAD2772"
                     /protein_end="418"
                     /protein_start="406"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="LARLNDLTKLNG"
     aSDomain        complement(18445..19308)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2772_Heterocyclization.1"
                     /evalue="1.40E-36"
                     /label="ACIAD2772_Heterocyclization.1"
                     /locus_tag="ACIAD2772"
                     /protein_end="292"
                     /protein_start="4"
                     /score="118.2"
                     /tool="antismash"
                     /translation="MPLTPMQKAYLLGKSKMFPLSQSSMHDFRELHGKIDAEIFSQRLT
                     ILVKHYSALRTMIDETRLVQYVVPKIELTNQLKIYDFRQLNISEAVRRLDLLREEYRYF
                     LHDLAISPWQIALIQLPEKAEVSSVVLTSFDGLIIDGYSISVLLDQLFDFTRDLNNLLS
                     SEEKKSNTDDIDFFNATEKDRQFWHEKLSQVDEVSQLPWANTLETITHPHYGRRSVVLA
                     KSQFDQLSKLAAQYKVFPNALLTTLILDVLSRWTEEQKLLISMPVSHSALHKTVGNSSS
                     FIVLDYQ"
     CDS_motif       complement(18541..18597)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2772_0001"
                     /evalue="1.70E-03"
                     /label="Cy4"
                     /locus_tag="ACIAD2772"
                     /protein_end="260"
                     /protein_start="241"
                     /score="11.5"
                     /tool="antismash"
                     /translation="VFPNALLTTLILDVLSRWT"
     gene            complement(19323..21815)
                     /locus_tag="ACIAD2773"
     CDS             complement(19323..21815)
                     /NRPS_PKS="Domain: PP-binding (5-67). E-value: 8.6e-11.
                     Score: 34.1. Matches aSDomain:
                     nrpspksdomains_ACIAD2773_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (107-398). E-value:
                     8.1e-84. Score: 273.3. Matches aSDomain:
                     nrpspksdomains_ACIAD2773_Heterocyclization.1"
                     /NRPS_PKS="Domain: PP-binding (741-806). E-value: 5.2e-13.
                     Score: 41.2. Matches aSDomain:
                     nrpspksdomains_ACIAD2773_PP-binding.2"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2773"
                     /db_xref="EnsemblGenomes-Tr:CAG69517"
                     /db_xref="InterPro:IPR001242"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR013624"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     132.4; E-value: 4.3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2773"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pe : putative enzyme"
                     /product="putative non-ribosomal peptide synthetase with
                     phosphopantetheine binding domain (EntF-like)"
                     /protein_id="CAG69517.1"
                     /sec_met_domain="Condensation (E-value: 3.8e-41, bitscore:
                     131.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.6e-13, bitscore:
                     41.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLQQEITAKIHQVLQVEDVHIQPQDNLIEHGLHSLAIMQLVDHF
                     EKRYSKALSYADFAMSPTVQDWHDLIQANENRNIADLNISESTAQLSLDVPTWLEQLPT
                     DLVPLSDMQYAYWAGKETEGVSAHLYMEFEGVNLDTVRLQKAFHTLVQRHPMLNVRIIN
                     GQQSIVSLEHQDIHLEDLTHLSASAIQAHLYAKRQRLTHQLLNGAEGHVLDVQLTLLPE
                     HRHVLHIDSDMSAIDPQSFLIVVEDLTALYQGKALPKLAVDQIEYFNYLEQRRQNVEYQ
                     TRLGQDQAWWQQQLDNIAPAPQLPQIAEGLRSDEHHFERLIHIFSEKERACLQSLAQTH
                     GVSVRSLCLTLFSYTIASWSSRSDFRLNLPTFIREPYGDDIRHIVGDFTQMSLLSLKLN
                     NHETLLETTKRIERDVDQIIEHYRYGGIHVLRDLSRHHQKLEISPIVFTSALDEGEIFS
                     KPLQDTLGQPIWCISQGPKVDLDVQIAYFNHGLAVNWDIRTHAFQPDVIEAMFQHYIKM
                     IHGLISKGSSAFDEKFKFELPQVQSDVRKKQNSRLPAKILSQFPKANEETQFRVLNELG
                     ADCPDWVLGRLILNINQQSNPNLEQWIDTRFPAYFDHQGQLYVIEQSHQLFFKNGYCVA
                     VQDLENRIQNISHVQNVKIYAMNDQQKSYCIALLELNQKLSSTELQTAYHQILPVYLIP
                     EQTYIVDQLQAFTSNTPIQDIQNFVQPHLSIEQMASQQPLQSTALERVVCFIMAKIIGL
                     PQQQAIVDIDFFDEGGDSLLATHLVTALNQYFKKSDVSVVDIFTQRNAKNIALLIEQKI
                     PDTAQRIATVFLQVIEGK"
     aSDomain        complement(19398..19592)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2773_PP-binding.2"
                     /evalue="5.20E-13"
                     /label="ACIAD2773_PP-binding.2"
                     /locus_tag="ACIAD2773"
                     /protein_end="806"
                     /protein_start="741"
                     /score="41.2"
                     /tool="antismash"
                     /translation="VVCFIMAKIIGLPQQQAIVDIDFFDEGGDSLLATHLVTALNQYFK
                     KSDVSVVDIFTQRNAKNIAL"
     aSModule        19398..21494
                     /domains="nrpspksdomains_ACIAD2773_Heterocyclization.1"
                     /domains="nrpspksdomains_ACIAD2773_PP-binding.2"
                     /incomplete
                     /locus_tags="ACIAD2773"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(20517..20561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2773_0005"
                     /evalue="2.70E-03"
                     /label="afterCy5"
                     /locus_tag="ACIAD2773"
                     /protein_end="433"
                     /protein_start="418"
                     /score="10.8"
                     /tool="antismash"
                     /translation="IEHYRYGGIHVLRDL"
     aSDomain        complement(20622..21494)
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2773_Heterocyclization.1"
                     /evalue="8.10E-84"
                     /label="ACIAD2773_Heterocyclization.1"
                     /locus_tag="ACIAD2773"
                     /protein_end="398"
                     /protein_start="107"
                     /score="273.3"
                     /tool="antismash"
                     /translation="PLSDMQYAYWAGKETEGVSAHLYMEFEGVNLDTVRLQKAFHTLVQ
                     RHPMLNVRIINGQQSIVSLEHQDIHLEDLTHLSASAIQAHLYAKRQRLTHQLLNGAEGH
                     VLDVQLTLLPEHRHVLHIDSDMSAIDPQSFLIVVEDLTALYQGKALPKLAVDQIEYFNY
                     LEQRRQNVEYQTRLGQDQAWWQQQLDNIAPAPQLPQIAEGLRSDEHHFERLIHIFSEKE
                     RACLQSLAQTHGVSVRSLCLTLFSYTIASWSSRSDFRLNLPTFIREPYGDDIRHIVGDF
                     TQMSLLSLKL"
     CDS_motif       complement(20631..20678)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2773_0004"
                     /evalue="5.10E-05"
                     /label="Cy5"
                     /locus_tag="ACIAD2773"
                     /protein_end="395"
                     /protein_start="379"
                     /score="15.7"
                     /tool="antismash"
                     /translation="DIRHIVGDFTQMSLLS"
     CDS_motif       complement(21246..21278)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2773_0003"
                     /evalue="5.10E+01"
                     /label="afterCy5"
                     /locus_tag="ACIAD2773"
                     /protein_end="190"
                     /protein_start="179"
                     /score="-2.2"
                     /tool="antismash"
                     /translation="DLTHLSASAIQ"
     CDS_motif       complement(21318..21368)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2773_0002"
                     /evalue="7.40E-05"
                     /label="Cy2"
                     /locus_tag="ACIAD2773"
                     /protein_end="166"
                     /protein_start="149"
                     /score="15.3"
                     /tool="antismash"
                     /translation="LVQRHPMLNVRIINGQQ"
     CDS_motif       complement(21345..21407)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACIAD2773_0001"
                     /evalue="2.70E-06"
                     /label="C2_DCL_024-062"
                     /locus_tag="ACIAD2773"
                     /protein_end="157"
                     /protein_start="136"
                     /score="19.6"
                     /tool="antismash"
                     /translation="NLDTVRLQKAFHTLVQRHPML"
     aSDomain        complement(21615..21800)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2773_PP-binding.1"
                     /evalue="8.60E-11"
                     /label="ACIAD2773_PP-binding.1"
                     /locus_tag="ACIAD2773"
                     /protein_end="67"
                     /protein_start="5"
                     /score="34.1"
                     /tool="antismash"
                     /translation="EITAKIHQVLQVEDVHIQPQDNLIEHGLHSLAIMQLVDHFEKRYS
                     KALSYADFAMSPTVQDW"
     gene            complement(21831..22616)
                     /gene="entA"
                     /locus_tag="ACIAD2774"
     CDS             complement(21831..22616)
                     /EC_number="1.3.1.28"
                     /NRPS_PKS="Domain: PKS_KR (55-169). E-value: 5.8e-07.
                     Score: 21.4. Matches aSDomain:
                     nrpspksdomains_ACIAD2774_PKS_KR.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2774"
                     /db_xref="EnsemblGenomes-Tr:CAG69518"
                     /db_xref="GOA:Q6F8U7"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR003560"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U7"
                     /function="1.5.3 : cofactor, small molecule carrier"
                     /gene="entA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2774"
                     /note="Evidence 2a : Function of homologous gene
                     experimentally demonstrated in an other organism; Product
                     type e : enzyme"
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="CAG69518.1"
                     /transl_table=11
                     /translation="MTMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVV
                     GFDLSIRNFMTSDHYEVHQCNVGDSSQVFDLCQKLLNTSPPDYFINTAGVLHLDGHDAL
                     PIEAWRQTFEVNTFAPFYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGASKAA
                     LTSFSKTVALELAEYGVRVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPL
                     QKIALTQDIANAVMFLISDQASHITMHDLVVDGGATLGQ"
     aSDomain        complement(22110..22451)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACIAD2774_PKS_KR.1"
                     /evalue="5.80E-07"
                     /label="ACIAD2774_PKS_KR.1"
                     /locus_tag="ACIAD2774"
                     /protein_end="169"
                     /protein_start="55"
                     /score="21.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TSDHYEVHQCNVGDSSQVFDLCQKLLNTSPPDYFINTAGVLHLDG
                     HDALPIEAWRQTFEVNTFAPFYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGA
                     SKAALTSFSK"
     gene            complement(22644..23273)
                     /gene="entB"
                     /locus_tag="ACIAD2775"
     CDS             complement(22644..23273)
                     /EC_number="3.3.2.1"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2775"
                     /db_xref="EnsemblGenomes-Tr:CAG69519"
                     /db_xref="GOA:Q6F8U6"
                     /db_xref="InterPro:IPR000868"
                     /db_xref="InterPro:IPR016291"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U6"
                     /function="1.5.3 : cofactor, small molecule carrier"
                     /gene="entB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:isochorismatase (Score: 295.2; E-value: 5.7e-90)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2775"
                     /note="Evidence 2b : Function of strongly homologous gene;
                     Product type e : enzyme"
                     /product="2,3-dihydro-2,3-dihydroxybenzoate synthetase,
                     isochorismatase"
                     /protein_id="CAG69519.1"
                     /transl_table=11
                     /translation="MTIPKIPSYPLPFKQDYPAAKVNWKIEKNRAALLIHDMQDYFVNF
                     YGEDSELIQQVVDNIAQIKAWCVANDVPVFYTAQPAEQKDQDRALLNDMWGPGLTAYPE
                     QAAIVKKLMPNEQDQVLTKWRYSAFYNSDLEKMLKDTQKDQLIICGVYAHIGVLQTAAE
                     AFMNGIQPFVVGDSVADFSLKDHLFALQYVQNNLGVVEDVECVIAS"
     gene            complement(23367..24554)
                     /gene="entC"
                     /locus_tag="ACIAD2776"
     CDS             complement(23367..24554)
                     /EC_number="5.4.4.2"
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2776"
                     /db_xref="EnsemblGenomes-Tr:CAG69520"
                     /db_xref="GOA:Q6F8U5"
                     /db_xref="InterPro:IPR004561"
                     /db_xref="InterPro:IPR005801"
                     /db_xref="InterPro:IPR015890"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U5"
                     /gene="entC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018:isochorismate synthase (Score: 331.5; E-value:
                     1.8e-100)"
                     /gene_kind="biosynthetic-additional"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2776"
                     /note="Evidence 2a : Function of homologous gene
                     experimentally demonstrated in an other organism; Product
                     type e : enzyme"
                     /product="isochorismate synthetase"
                     /protein_id="CAG69520.1"
                     /transl_table=11
                     /translation="MYYKGNGFMNDMNLSIDHAIELNINLESSCFLTKDYRLLASDLAE
                     VVKLAACDYEKLSQTITDSFQKLKKDPNANPILVGAIPFDTTQASSLNIYRNHRKQRQL
                     VISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQN
                     PFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDE
                     NINQSRIHELYASEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVF
                     DGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGN
                     GEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKTLSATFHS"
     gene            complement(25287..26231)
                     /locus_tag="ACIAD2778"
     CDS             complement(25287..26231)
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:ACIAD2778"
                     /db_xref="EnsemblGenomes-Tr:CAG69521"
                     /db_xref="GOA:Q6F8U4"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR018060"
                     /db_xref="UniProtKB/TrEMBL:Q6F8U4"
                     /function="3.1.2 : transcriptional level"
                     /inference="ab initio prediction:AMIGene:2.0"
                     /locus_tag="ACIAD2778"
                     /note="Evidence 3 : Function proposed based on presence of
                     conserved amino acid motif, structural feature or limited
                     homology; Product type pr : putative regulator"
                     /product="putative transcriptional regulator (AraC family)"
                     /protein_id="CAG69521.1"
                     /transl_table=11
                     /translation="MSGAFKMSIYIDSHKVVLKQVGDIFLDSCSPLPNHHLNHFNPSDG
                     NGYSEIYDFGKLCVGKGKYWIDHPLQMSAETPAHSFGITILLSGTHHIQNHKSNHKYEI
                     RSPMIILRKGSLGLQTIHLQEHKEMSLISLDFNQSFLEIMESNSLNSDFANFFLSEPST
                     ALKTINIPNKNVLHQAHYLLNIPSAQSSIDLLHLEGAALELMSLLLGNNQKSNEIPSSV
                     QRTIFILENEFEKKITIRTLAKQVGINECDLKKIFKEYTGKTIGHYLLENRMRCAQILL
                     KEGVSIEKVANQIGYSSTQYFKKIYERYFSYSC"
ORIGIN
        1 tcaactccgt ttattcatta ttcccgttac atgacaataa ctttgaatag ttaataaaac
       61 agcagctaag ctaatgccac aagtcaatac aatccagatg acatccacat tggcacgcac
      121 ttgcaaccac ccttgtaccc ccattaaata acttaatgga ataattacaa accaatagca
      181 aaataaaata ataaacaagg gttgcataaa ttgatgtaaa ccacgtaaga caccagaagc
      241 taccgtttgt attgcatcaa aaattaaaaa tatcgccaca tatgacatta gaccaacagc
      301 aacatttaag acttcagcat cttgagtaaa taagcttaca atgtgttgtg caaaacctat
      361 caaaattcct gccatcaaaa aactatagat cagggtcaac acaactacac ataaacttgt
      421 agatattttt ccttggtgat gattggtcgc agaaaaataa gcaattctaa ttgttgttgc
      481 actacttatt gcaatcggaa tcatgatgat cagcatagca atattaatta caatttgatg
      541 cgctgcaatt gcttttgcac caagctgtga agcaaaaaat gccagtgttg ccaatgctaa
      601 aatttgcaga attaaagtaa ttcctatagg taagccttgc tttaacaaac ctaaactttc
      661 tttaaaacca acttgaatgc gtttaatttt aagttcagga attgcttttg aaacaaactg
      721 atacatacaa aaacaagcaa tataagcact catagctgtg gctaaacctg ttcccgctcc
      781 ccccatttct ggaataaatc caattccatt aaccaacacc aaacacaatg atgcatcgca
      841 aacaagtaaa atcgcatatg tcaggataat tggttttagt aaactatgac cttcgctaac
      901 gaagcgaaat agtgtcatat aaactaaacc tggtacacca aaagcaacaa agtgcagata
      961 ctgtttggca atctgtgcca cttgctgatc gccaatgagc caaggacaca aaaatgctaa
     1021 taattgaatt aatataaatc caaaaatcga aagtaaaaaa gcaactcttt ttccttgttg
     1081 aataagtact ccaatctcct gagaactgtg ttgttgcatg gcagaaattt taggtaccaa
     1141 tacatataaa attcctgtaa ataaaatgaa tacaggcgtc cacatattac ttcctaatcc
     1201 aattccagct aaatcaatat aataataccg acctgccacc atagtattaa tcacccctag
     1261 agatgcctga caaatttgaa tcagaatcaa tggaagtgcc aatttcaaaa ttgggaataa
     1321 gatgtctttt aaaatattca tcgtagatct acaagtattt agtctttagg ttcctgtgga
     1381 ttaatgggct ttttgaagtc gccaatatcc cttgatatga ttgtttttac cctgtaactt
     1441 tctttcatta cgaaaataat gacggatttt tttagctaca ttattttcta atgcacccca
     1501 aacattatcc aagtgttcaa actcatttag aatctcaatg atttctatac tctgattttc
     1561 taaagaaccc acaatatttt tgatgataga attttctggg aaatcataat ttttaaaata
     1621 atcaagatcg ctttcatttg cacaaagcaa aataactaat ggagggtgtg ggttactcca
     1681 aaaatctaaa attccagcta aagctggata agctgtttca tctgctatta atactgctgc
     1741 gccattctgg agatgatcat gtttgtcgtc tgtttctgta cggcttgaaa taagtgaacc
     1801 tacattgagt tgttgtaccc attgactacc aagactgttt ccgtgagtaa agatgtctac
     1861 ataaccataa tttaaagcgt cttgaccctc atgaccaaaa gattgtctta acgtatataa
     1921 gcgaatatcc ttgttcatat tttccatcaa tttttgtctt ttctgagcag ataaatgttt
     1981 cattacccat agaaaaccac gatcaacaat attctttaaa acactgcttt tatttgaact
     2041 gcttatattg atttcgggtg ctttttctaa tacctttaaa ataaagccat atgcatatcc
     2101 agcataatat tgaggtaatg caatctgact tttaatggtt aatcgcgtaa tattttggct
     2161 tacttgagat ttctcaatga cctcaaaaaa ctgtttggca ttattactaa attctatttt
     2221 ttgtttggca aatgaattat aggccaaata aagaatttgc tcttcaagat caccttttaa
     2281 ttcaaattga ataaataaat cttgttttgc tactgaaaaa gggtcttgcg tatgtaacaa
     2341 aataccttct tcataaatat cgacaattac agcatcatca atcgcattat ttttaccata
     2401 agtttgagca atgatcagta actctttatg atgatcctga ttcacatgat ccatgatatc
     2461 aagcttacga tcttgatctt taatcgtggt gaagtgtttc ataaagccgc ctaaatttct
     2521 tagataaaac aaatgaaaga gaataaatat acaaaaggtt aagttggtac attgggatca
     2581 tcaggtgaca ataatttcca tgacaaagca gccacaccta aagcacatat aaaggttaaa
     2641 atcacgacag cggtataccc aatatgttgg gccagcgtta aaccgagtgc tgaatataca
     2701 aagcccatga aaacgaccag gctaagttgt aaactaaaga acgttgcttt tgctggcata
     2761 cttgcagcac gatccataat aagtgtagaa agcgtcgcaa ttagccctgg attggcaatg
     2821 aaataaccaa aaattgccaa atacactatg agttttgagg tgtatcccaa ggtcaaagga
     2881 ataaaaagta acaacgtcag gccttgcatg accgtcagcg taatcagtgc ttttttacgt
     2941 tgtaattgat tgatcaaaag cgtggcaagg aatgccgata agatgccaat aatcgaacca
     3001 aagactttag tggcaaaacc aatatcaacc aatgaccact ttgcatcgac caataatgga
     3061 tttaggattc caaatacagc agtgaaacca attggataaa taaataacaa cacaaaccaa
     3121 gacttatgct tggtgataaa taatttaagt tgctgagcta aacttttgaa ctgagaagaa
     3181 agattatgat gcggattcga aaactcattt tcaggttcac gataaaacaa taactgaatc
     3241 caggttatag cagttaaaag ggccaatata ataaatgcgc ctttccattg taaccaagga
     3301 tataaaatca ggagcaaacc gccgccaatg atattgccca acaagttact ggcatattga
     3361 atactattcg caaattgtcg ttcagaggcc tcaaaaatct ttgtggctaa accatctata
     3421 gcaacatctt ggatactcat aaacaagcta taaacaataa agagtaccag catgattgga
     3481 aattgtttgt ttacctctaa ataaccacat accagcagta gccccgtcat acacaattgt
     3541 gcaaacagaa gccaacttcg atactgccct tgggtgaata atctaaaact gtcaacaaat
     3601 ggcgcatata gaattttacc cagcattgga agcgcaatca gattcaataa tgctaattta
     3661 tcaagtgcaa taccgtgttg cctcaaaatg gcaaaggtag cagacatcat aaaagcaata
     3721 ccgatatatt gtgtagtata ggtactgatt aatagcagcc aaggtttaga atgatgagac
     3781 atgataggtc ttccaatgca tgaatattta aatagaatta aaaatcgatc tgcatagata
     3841 acttatatgt gcgaggatct ccgcctacac cgacatagcc attccataca cctgcccaat
     3901 gttttttatc aaagacatta tcgatgcccc ctctaaacac aacattacgt tgtgcaataa
     3961 cagtggcata acgtgcacct aaatcaaata tgatccaatc tggcagtttt tgtgtattgg
     4021 cattatctgc atacatgctg ccggtataaa cgctatttgc agtcaatgtt aaatttggtt
     4081 gcacaggcag atcccattcc acaccaagat tagactgcca gtgtggaatc cccatcacat
     4141 cattaccttg atatacccca cctgcggttt ttgtatattt ggcatctaga taagaaactc
     4201 cacccaataa acgcagatgg tcaactaaat ccccaactgt tgtccattcc accccacggt
     4261 tacgttgctc accatcatca ctatagatat ttgtagtggt atttttaatt aggctgggct
     4321 tagtgatctg gtaaaaactc aaggtatttc tgaaattacc caaatcccat tttgtaccaa
     4381 tttcaaattg ctttgattta tatggtttaa atactgtatt cacattagcc gctgtagtgt
     4441 ccgaaacggt atcaccttgt gataaacctt ctatataatt tgcatagagt gataaatgat
     4501 taccccatgg ctttaataca accccaaccg ctggtgtcaa agcactttct ttatatgctg
     4561 gattcaaggc attcgtggca ggattaatac taaaactttg ggattctact cgttgctcac
     4621 gaaggcctaa aataagctga tatttatctt gtaaaacaga caaagtatct gctaatgcaa
     4681 cactggatag ttttgtttca gaaatcttgg gtacattggc tggtcttacc gcatttgttc
     4741 caggcttagg attataaata ttggattgcc aaggtgagcc aacacttaat cccatatagg
     4801 tattttgatc aattgtattg ccacttaaaa ctaattgatg tttgatttgt ccagttgtaa
     4861 atgttccacg gacacctgtt tctactgcat tgacatcggt gtcattggca ttcatacgag
     4921 aaatagcggt gtaatcacca ttaggctgtg cagccatacc tagagcgtta ttcgcaataa
     4981 caccatgact tttttgtttt tttgttccaa cagtggcata tgcggtccaa tcatttaaaa
     5041 aatcatactg tacattcgca ataagtcctt tggctttggt gtgtgcataa ctgcctggtt
     5101 gagtattaat ttttgaatct ggtgcttttg gaatatctgc agaggcaaaa ctcaccatca
     5161 atggcatacc gccatcaact ttttcattga tatcgtataa atcaaggctt gctcgaagtc
     5221 tatctccttt atagtctaaa gcaatagagc ctaaagccct gtcttcctct tgaccatcta
     5281 aaacagtatc accaccagac tttagagcat taacacgaat gccaaattgt ttttcatcac
     5341 caaaacgacg acctacatca agatgtaaac ctaaattact gtccgaagta tatgttgccg
     5401 ttactcttgt aagatcttgt tcaccagccc gtttaggtac aacattaatg acacctccaa
     5461 cagccccccc caaagacata ccattaagca atgcactggt tccacgaaat acttcaacac
     5521 gttctaaaaa ttctgttgga atacgattat gtggtactaa gccgaatagt ccattccaag
     5581 ccatttcatg gctttgagta tagaaaccac gaatattaaa gtattcacca agcccatttc
     5641 ctgaaaatac gctacgtaca gaaggttcat ttttcaatgc ctttgcgata gaggttactt
     5701 gttgatcttg aatatattga gcagtgtagc tggtaacatt aaaaggaata tccattgtat
     5761 ctttgtcacc cagcataccg acttgactct ttttagtcac ttggccattc gacaaagtcg
     5821 tattatcagt cgcctctgct ttaacgataa tcgtaggaag ctgttgagcc gactgtgtat
     5881 tctccccagc aaatatattc tgagttagca gcaatgtgat actgatcgat aaaattgctt
     5941 ttttgaaatg gatactggta ttcatttctt atcctaggaa tagtaatgtt taaattatgt
     6001 tacgcataat accaagaatc attctcaaca aaaaaaacga tcagaaataa ttcaataaaa
     6061 cagggaaagc atttgaatta attaaatatt ttatgaattt aatttttttt aagttagatt
     6121 agatttgaca tctagcagat aaatagtatt ttaaagtaat tctcatttgc atttataact
     6181 gcatatttta ggctcgaaat ttatcagtca ctcttatgaa caacaattca aaaattaatt
     6241 tattttgtgt tccttctgca ggaagcagtg catcaatttt tagtgcttgg gataaaacaa
     6301 gtgctgaaaa tttaaaagtt attgcgcttg aataccctgg tcatggacga aaaattcagc
     6361 agtccctgag tcatgatcct gactttttag ctcatcaatt tagcttagaa attttagctt
     6421 atggtaatac gccatatgta cttttcgggc atagtgtcgg tgcctcattg atatggaaaa
     6481 ttgaagaaaa actcaaactt ttacatgctg atcataacct gattctaaaa attgtcagtg
     6541 cccgcccttc tcctcttttc caaaatttaa ttcataacta tagtcatctt accgatgagc
     6601 aaatgatcaa agaactcaga ctttataata attttcctga tgaaatatta aacaatgcaa
     6661 gtgctttaaa tttttttctt cctattatta aaaatgactt cattctaagt gacaacatgc
     6721 tgaaaaaacc tatttttaaa agttcagttc ctcttatgag tgtttatgga gaagcagatc
     6781 cgtatatcaa aaatcataat attatggaaa gctggagtac ttataccaat aaatggttag
     6841 gagctcatca attttctgga gatcacttct actttttaga tacaacaatt ttacaaaaaa
     6901 tgcttcatct tattcaggaa aaaatttacc ttttaatgaa aacaacactg gtttaatttt
     6961 ttaaattaca cattcatatt atgtttaatc aagaatataa acagacacct ctgaattcag
     7021 aacaatattt agaactaaaa ttttctaata ttgatttcga acattctatt ctaaaaaccc
     7081 caaaaataat tatccatcaa attaatttgc tcgatataga tgcacaaaaa atttataatt
     7141 tatataataa atataatatt ttcctcccta aacacgttac caaagcgagt ataaaacgaa
     7201 aatgtgagtt tttcttaggg cgtttagctg caaaatacgc attaaatgat ttaggtaatt
     7261 attcctcttt tatcatagaa agaggtaaac aaggcgaacc tctatggcca gatcaaatta
     7321 caggaagtat tagccatagc atgctggact gcacccaagg aatagcaatt gcagcaacat
     7381 caaggctaag caaaaatatg aatgatttaa aagaattatc aaaaatctat aatcaaacag
     7441 cctcattatc tggacaattt ttaggaattg acattgaaat taaaaaaaat tcagaaatat
     7501 ttgatcgaaa tccaagtatt ttaaccaata tattcagctc tcaagaaatt aagttaatca
     7561 gtcctttttt aaagcaacga cctgtattac acttaataat attttctgca aaagaaagtt
     7621 taataaaagt agtttacaat aagtataaaa aaatcatttc tttcgacacc atgcattgta
     7681 ttaatatttg tgagcaaacc caaactttta tgttttatat tccacaaatt tcaaataatg
     7741 aaaaattttt agttaattat attgaactag actatcaaat tttaacttat tgctgtctaa
     7801 aaagctaaat aaaatatatc aaatgatagg ctaaaaatcc taaaaacact ctgctaacta
     7861 tattcattat agtttcccca tttagcactt attatatcag tcattttacc tacaaactac
     7921 attattccaa caaaaaaatc aaaatattga aaatactatt ttgatctttt tattccacat
     7981 taattaactt ctgttatttt taaatcaaga ttaactggct tttttacgtt taaattcctc
     8041 ataataatgc ccacactgtc gataaaactg ttctctaaag cagtgatata aaacagccgt
     8101 tttttcctgt agcttaattt taccctgttc atttaaagca atatcctgtt taattttttc
     8161 atagaccaac attgtctcat caggttcacc aactactttt cctgctttag aatgctcaaa
     8221 aattaagaaa cttagcatac gcatgacagc acgaaaatgc cctttaccaa ctgcatcttc
     8281 actcaataaa acatgccaac ctaaatcatt ttcttctgca tcataatata atgccaagcg
     8341 atcacgtttt gcctcataaa tttctaaata gccaacgtct ttccgatcaa tttgaatgat
     8401 atataaatgt tgatgatcat cacaaagcat tctttcaaaa taaacagcca gttcaagttc
     8461 agatttattg agctgccact gcggaataat atgcggttga tgcatccatt tgactagtaa
     8521 cggtaaatct tgtgggagta cgacatcacg taaagtatat gaaacttgat gttctgcata
     8581 atcaaaaaaa ccaggcaatg cttttgatat tgtcttcatg acgagtattc tctttgaaaa
     8641 taacagcaaa attttaagaa ttaaaaggat actttttaat gaaaagcatc ccaagtaact
     8701 aactaattca aagcataata ttgcagtggt ggaaaaccgt taaactcaat cgagctataa
     8761 cttgtggtat atgcacccgt cgacaaccag tacaaatgat cgccaatttc gagagataat
     8821 gggagttcat attttttgtt ctgatacatg atatccatac tgtcacatgt tggacctgcc
     8881 aatatgatgt catcactgtt tccagttttt ttacacataa ttggatactg gattgattca
     8941 cctaatgttt caattagacc attaaacaca ccaacatcgg tataaaccca acgctttgta
     9001 cccgactgtg gtcgctgtga aatcagaaca atttcagaaa ccaaaatacc tgcattgcct
     9061 actaatgaac gtcctggctc taaaataatc tgttctagat ggtaagactt gaatatctca
     9121 agtgccgcat taatttgctt agaatagtta tcaaatgctt ccgtttcctg aacatattgt
     9181 gcaggtaatc ctccacctaa atttagcatt tttagacgaa tattatgttc agtggctaat
     9241 acatcaaaaa ttgctttagt ttcctgtaaa gcactgtccc acaagtcaat ttttcgttgt
     9301 tgagagccga catggaaaga aataccatat ggaatgagac ccaattcctt ggcttttatt
     9361 gctaatctga taacacattc agcattacat ccaaacttac ctgaaagtgg ccaatctgct
     9421 gtttctgaac catcaattga taacctaaaa aataccttag aacctggagc atagtgtgca
     9481 atgttattta aatcgatatc cgaatctgtg acataaagtc gtacgccttg atcataaaaa
     9541 tattgaatat cgatacgttt tttgatggta tttccaaaag ctaaacgtga tgcatcaaca
     9601 ccaaatgctt gaactttttt taactcatta acggaagcta aatcaaaatt tgagcccaat
     9661 gagtttaaac gatcaatcac ttcatttgca ggattagctt tcaatgcata ataaatatct
     9721 gtatttggaa aaccttgttt taattctaaa tagtgctttt caatcacact cagatctaaa
     9781 actaaaaatg gtgtatcttt agttcttacc aaatcttcca aatgatcttt catattgctt
     9841 tggaaataca ggggtaactt cattttaata tcctaaaaat ataattttgt gtgctgtggt
     9901 ttaggctttg tttttagtgt tgtcacaatt tcatcttcca aaggtgcaaa ctcttggtaa
     9961 gcaattcgtt tttcaacagg ataaacttca cgccctaaaa tgctattgat aatgatggca
    10021 ttgcgataac agcccatacc taaatctgga actgtgaatc catgtgaata aatgccaatg
    10081 ttttgtgcaa aaatagtgtt tttatcgtta atgctataat tccaattaac ttgaatacgg
    10141 tttttattgt cccagttgat ttgcgaacga attggtgtca aacattctgg aatgttgtat
    10201 tcatatccaa gcgcaagaat caaaacctca ctgtgtaatt tgaaactttt attaatatct
    10261 gagtttttaa agatcagatc taaatgtgag tcttgttgag tcaccatttc taaagcacaa
    10321 tttggcatca tacgtgtcgc tatcggagca taaagtgatt tttgatataa aagatcatag
    10381 attcggttga caaaacttaa ctcaatacct ttatataatg cactttgaga accaatcact
    10441 tgatcacgct tattttgctc aagcgaatga aaatgtgaag tataatctgg tgaagtatat
    10501 tctagtgtta acttacccaa atccattgaa aagaaatgcg gagcttttgt cagccaattc
    10561 aattgatatt catgctgatc tatctcacta agtaagtcat aataaatttc tgcaccactt
    10621 tgcccaccgc ccacaatggt gatggatttt ttattgagat aatctttttt atattttaaa
    10681 taatctgcgc tagaatgaac attatctgag tagccttgac agaattttgg cataacagga
    10741 gtagttcctg tacccaatac taaatttttg gtgatgacag ttatctcacc ttgaggttgt
    10801 tttactgtga ctgtataaag ctcaccgact tcatcataat ctatttcatc gacaaaactt
    10861 ttaaaatgaa cattctcaag ttgtgatgtg acccatttgc agtaaagatt atattcagca
    10921 cgtaaaatga aaaaattttc acgaataaag aactgatata gtttattgtt aagctttaaa
    10981 tagttcaaaa aagagtagtg actcttcgga tctgcaaaac tgacaaggtc agctataaat
    11041 ggaatttgta atgtactgcc ttcaggcata atgccagaat gccaatcaaa ctcctcttta
    11101 ggatcaaaaa aaatagtttt taattctgat aatggagctg tgagacaagc taaccctaaa
    11161 ttaaatggcc ctacaccgac acctacaatg tcataaatct gttgtgtact catttttaat
    11221 tccttcttat cccagttttt gtctatttac tttaccaaca tgggtatatt taaaatccgc
    11281 tacaacgtct atttcatctg gaattttaaa atgcgcaata tttttacctg ttaaaaactt
    11341 acgaatattt tttaaactaa tttcatgatc ttcatgttta ggaatgatga tggctttaat
    11401 ccgttcaccc aaatgttcat cgctgacacc aatcacgcag acatctttaa cagttggata
    11461 ttgcaaaatg aattcttcaa tttcgctggg tgtgactttt tctccagaac gattaatctg
    11521 ctctttctca cgtccagtca cgacaatatt gaggtcatca tctaaatagc cgatatctcc
    11581 tgttttataa aaaccatcat cagtaaatga acggcgatta atttcatgca agttataata
    11641 gccattaata gtgtacggac cacgggtttg aatatgacca atcgcattga ttggcaaagc
    11701 ttgtccatga tgatcagtaa tgcgtatttc atctaaatgt gacagcttct taccctgggt
    11761 ttgaatagtc accgcattgg tatcatctaa atgagtgaaa tttactaaac cttcagccat
    11821 gccatacact tgttgtaatt tgacttggaa ctgatcaata atttgctcag caagtgatgg
    11881 taaaagcttc gctccaccta cttgaatcac ctttaaacta gagagatcgt agtcttttag
    11941 actttcggca ttgagccata aagtagcaat tgcaggcacc aaagacacct gttcaatctt
    12001 gtatttttgg atcagctcaa aacaaactcg gggttgtgtt aattgactca gcaccaccgt
    12061 tccacctgca tagaacacac caagaaaacc aggtgaactc atacaaaagt tgtgcattac
    12121 aggtaacacc accagttgct tggtctgtgg atttaaacct gcaacctcga cacttttttc
    12181 aatcgaataa atataatcag catgagtgcg tggaatcagt tttggtaaac ccgttgtccc
    12241 ccctgacagt tgtaaaaatg caatgtcttc tgaagaactt aaagcttgaa tattggtatc
    12301 taagttgaga tgttttaact gaggtaacga gcctgcaata gtctcttgac tcaatatcgt
    12361 ttctctaaac caaagctgaa agttcggcac agaaaattct tcacaaacat cgactgcagt
    12421 gatttcatta gccgtaccac ataatttgat aaaccctact gcacgacttt gccgtgcaat
    12481 attttcaatt tcataagcgc catgaccatg caaacaaaag actggtcttg caccaatggc
    12541 atataaacca aaaataacaa taaacacttc aatcacattg ggtgattgca ataaaacaaa
    12601 gtctgtttct cgaatacctt tatgttttaa gtatgcgccg tagcgaatgg catagtcata
    12661 caattgttta taggtcagtt gtttttggtc ttgaatagcc gcaatacagt caccaaaacg
    12721 actaactgaa tctgctagca tttgaaaatg ggtattcgat ttccaacaac cttctgcacg
    12781 atactgtttg gctctcgatt caggaaatgg aacatagcct tgttgaatat cttgttctaa
    12841 aaacatgaac tgaatccttt aaattgccaa ttctggaagt tgaatggttg acagctgatg
    12901 acggatttcc atgacatcaa tctgcgtgca ttcttctgac tgcgtatcga tgtggataaa
    12961 actttctaaa acctgttgcg ccacctgacg aatcaattga atttgtatct cgttataacg
    13021 atttacacga tagttaatca ccacacgcag gcgttctttt tcagaactcg gctcttcata
    13081 aacttcaaaa tgcaaaccaa atttagctgt atctcgctct ggttcaatca attcaaagcc
    13141 tatttcgtca ccagaattaa gttggaatac acccgttaag gcattttgag catgtagttg
    13201 cacataaact tcatatgggc tttctgtcca ttcttcacct tcagcgcgaa tattgtcttc
    13261 tacaatggca aatggaatat ctgcatattc ttgtgcttta aagatattgt tctgaacttg
    13321 attaactaag tctttaatgc ttaagctttc attgaactgt atgtaatgca tgactacatt
    13381 ggtgaaataa cccagcgtat cttgataatt tggatcttgg cgacacgcca ctgatgtccc
    13441 agacaaaact tttttacctg cacccaagta ataggtggtg agtagtaatc cggcatagac
    13501 tacataaaat aaagaagagc gatactgacg tgctaaagca tacagttgct caacttgtat
    13561 tgccgtaaaa ttaaattcaa cagcagcgcc tgaaacatca tctagattat tttcaggagg
    13621 tggcatatct acatcgttcc tgtaggctgg caataacggc tgttgttttt ttattttccc
    13681 aatcgtgttc atccaatatt gaatatgtgc ttgtagtgca gaatcatctt gcgccattgc
    13741 atattcgtga aattggcgtg gtgttttctc ccaaattggt gcttttccgt cgacacggct
    13801 tgtataagct tgaatcaact cacgcatcaa aatacccgac gaccattcat ccatcgcaat
    13861 gtgatagagc aacatcgaca gaatatgctg tccctgttca tctttcataa aacgaacacg
    13921 aattgggaac tcttgcatca aatcaaaaga atgattcgct tcagcacgta aaatctgctg
    13981 ggcactttgt ccaacctgat gttcagaacc ccagaaccat ggatgctgat ttaaccgatc
    14041 catcggaatg accgtttgaa aaatctcacc ttgatctgcc tgaacaaaaa tactgcgcat
    14101 tacatgatgc cgttttagaa tgtctaaaaa tgcatcgtaa aaagcctgtt catttaccgt
    14161 ttcactaaaa cggaaggcaa atggaatatt gtacatcgca tcccggcctt gatttgaaaa
    14221 gcccataaac gctttttgca ataaagtcag tggtgccaca atttcacgat tatcatctgc
    14281 tactgagctg tccttaactc gatcactcaa atattccaca cattgcgata attccaatgc
    14341 agtcggtgca ttgaagaaat ctgcaatttt aatgagcaat ccatgctggg tttgcaattt
    14401 gccaatgaca cgcgtagcta aaattgaatg gccaccaaaa tcaaaaaaat tatcatcggc
    14461 ttgtaaattt ggattcatca ggacttgttt aaactcatcc agaatcaatt gtgtaattga
    14521 tgcatctact tgtggttgaa ccgatgaagt tggttgagcc caatgttctt gatcagaacc
    14581 atatggagaa gcctgatggc caaatgcaaa aattgctgct tcttcaagcc gctgctgtgc
    14641 atccagatgt aaaaattcaa tccattgctc tagtagtaat aaaccaattt tcttagataa
    14701 tttttcacct gtggtgagtt caaaatgaat ctcatcagct ttaatctgaa aggccaaggt
    14761 caagtcataa tctgaatgaa tgggcggaat gatcaatgtt gatgtttcaa cttgctccaa
    14821 ttttaagaat tgactgccat cgataaattg cgtcactaaa acatttggaa tcgtgtttct
    14881 tttcgttttg gtagcagaca aaatctgttc aatcgaaata ttatgaacca tgccctgcaa
    14941 tatttgattg cgtacattta caatcgattc tttttcttta ttttcaatat tcgattcttg
    15001 ttcagagtat tcaggccgta aaattcggat aggtaaaata tttgaacttg accgaatttg
    15061 gctaaggcta gatgcttcat actgttcgac aatcggtaca aaaagatcaa ttgactgtgt
    15121 accaaataaa tgatttaagt accctccaaa ctgggcaacc acggtatgaa aaatcgatgc
    15181 ttgcgcccgc tcgcttaatt gttttaagcc cttcaatggt atgctgctag agcaacgtac
    15241 agctttttgc tcataatcaa agattgtatt ttgaccatac tgaattattg atgcttgaac
    15301 attcggtgct cggcaaaatt ttggccaatc taactggttt aatcccgtag gaaatatagt
    15361 tttccaatat tgcaatgcat tttgggaatt caccaaaact tttgctggta ttttagatga
    15421 taattcaatg tgtgaattcg atgctgttaa cacaccgtca agctgtgcat aattctggct
    15481 aagctgcgca aaaatgggtt gccaagcaga atcatctaac aagatatgat gtcctaaaat
    15541 acctaaaatg acctcatgat gactttgcgg cagtagcgta aactgaatcg ctggagcttt
    15601 cgccaaattg atcggtttct gaatccaaga caacagatac tgaaccgctt cttgttcaga
    15661 cttgaccaca tgaatattca tctcaaaagg tgtgtgttca tcatggtatt tatttaatat
    15721 gccttcatca tccaagtcat aacgtaaatt tagatttgaa tcaccctcat aaagtttttg
    15781 aatggcattg gataatcgag aaatctcaat ctcgccactt aaccgaaacg ctaatataaa
    15841 tggtcctgaa gatgccaatg gatcttgttg atgcagcatc catgcacgtt cttcagtaaa
    15901 agaaagttgc acaccatttt tttcaatgtt tatgatctga ttttctgtgt aatgttcaac
    15961 cgcttcagtt gagatacgct ctgataatcc aatatcctgc aacttacttt caaataaact
    16021 caataagtca tcactcatga tggatggttg gttactcatg ttcgactcct ttttttattt
    16081 ctgatgtagt tgtgattcaa tattcatgac gatgtcacca atagttttac acttggctaa
    16141 atcagaaaat tggatcgaag tattgagctg ttgagaaaaa tgcttcgcta aacgatttaa
    16201 atgacctgaa ctaataccta gcgctaaaat ttctgtatcc aaaaataaat cggcttgacc
    16261 tgtatgattt gccaaagaca tttgcagatg atgaatcacg tctttcgcaa tagaaggttg
    16321 ctgcgctgtt tgcgtaaaac ctgttgcttt actcgtttgt tgagtgccat gggctgtatc
    16381 ttgtacttct tttactgcac gaaaatttgg atgatcattg gttgctttgg cataagtttg
    16441 atagagaaaa tcatgagcca cttgctttaa cgttttacgg tcaatttttc cattacgggt
    16501 aattggaaat tctgctaaag gtacccaacg tgatggaata tgtgagttcg gtacatagtc
    16561 ttgtagaaat tgacgtaact cagatggacg catactattt aaatctgcat gatcggtctt
    16621 gtaaatcgcc accaactcat tgccttcata cactggattg gtacaggtta tgaccacgca
    16681 gtcggtaatc tttgcatgtt tcaataaggc attttcaatt tctgatgccg caatacgcac
    16741 accacgtact tttaaatatc cctcatcacg acctgcaaaa ataatattgc catcttctct
    16801 taagtaacct ttatcactca tgcgaaacac acgatggatt tcaccatttg gtaaggttaa
    16861 caacacaaaa tccttttgtg tcaacttgcc atccagtaaa taaccattgg caagattaat
    16921 accagacatg tacaactgcc ctaccacacc tggcggacaa aactcaccaa atttatttaa
    16981 gatgtaataa cggttatgca ccatttcctt accataagga atgacgtcga tatcttcaga
    17041 tgtaatctca tgccaaatac tccaaattgt agtttcagtt ggaccaccaa tcgaaatcaa
    17101 acgagtattc ggtaaaattt cacgaagttt ttgcacgaca gaaggtttga cataatcacc
    17161 gccttgatta atcagacgaa tactttgtaa ttgactcggt tcggctgaag tgagcaacat
    17221 atcgaccatt gctggaacag tacaccagat tgaaacctgg tatcgttcaa tgagttcagc
    17281 ccatgccaca gcacttttcg cttcttccag agttggaacc accaaagtgc ctccaacaga
    17341 caaaggagcc atcaaatcaa aaattgacat atcgtgatgg aatggcgttg ccgctaaatg
    17401 aatatcctta tcattaattc cccagaaatc aatggtttcc tgtagtacat gcgctgtagc
    17461 acggttattc agtaccacgc attttggtgt acccgtacta cctgaggtat ataaataata
    17521 ggcaggtgat gcatcataat ggtggtgcca acttagttca gattcaaact tagattcagc
    17581 actaccagaa tataaatttg aattggatga aacctttaaa atttcatcaa tattcagtgt
    17641 gagtaaacct tcaataggtg aagtcgaaat ggctaaatct gcacgactgt ttttaagaat
    17701 gtactgctga cgtaattttg gtgagtccat atcgacaggt aaccaaacaa tccccgataa
    17761 agcacacgct aaaatcgtat aaatatgttc aggactttta cgtaaacaga tagccaccac
    17821 ttggttttga ccaatttgtg ccaaatcaag tgcacggcga actttcgcaa catgagcacc
    17881 tagctcagca taagtaacct tctttccgtc gtaaattaaa gcggttttat ttggaatttt
    17941 ttcaaataaa tgacactgaa tattggctaa ataatcaacc acttcaacat gttgataatc
    18001 atccgaaata tctgcatcat cggataaaac tgctatattg cagatgtgct ttggctgttg
    18061 taattcacca ttcagcttag ttaaatcatt gagtcgggcc aacaatgcat ctgctaaatc
    18121 ttgaatcatt gtttcactta atgcctcttc aacaaaatca agatcaataa ctaattcaga
    18181 ttgtgcagat aaagacaaac gaatatctaa agccaattgc ggtgtttgtg tttgcccaac
    18241 agcataacga atatgatcat gttgtggtgg tttaacccat gacaaaccat tggttaatgc
    18301 cacaggtaaa acaattgatt cttttaaagt tctcatcaaa tatttagata gttcaatgcc
    18361 agaatatgag gtatggccca tacattccaa aatttgtttt tgggtcgatt tgatttgatc
    18421 gacaagactc atttctggag aatattgata atccaataca atgaaagaag aactgttgcc
    18481 cactgtttta tgcaatgccg aatgagatac aggcatagaa atcaacaatt tttgctcttc
    18541 tgtccaacga gaaagcacat ctaaaatcaa tgtagttaat aaggcatttg gaaaaacttt
    18601 atactgggca gccaactttg ataattgatc aaattgcgac tttgcaagca ctacactgcg
    18661 acgcccataa tgtggatgag taatggtttc aagtgtatta gcccaaggta attggctaac
    18721 ttcatctact tgtgataatt tttcatgcca aaattgacga tctttttctg ttgcgttaaa
    18781 aaaatcaata tcatccgtat tcgacttttt ttcttcacta ctcagtaaat tgtttaaatc
    18841 acgagtaaag tcaaataatt ggtctaaaag aacagagatc gaataaccat caataattaa
    18901 accatcaaaa ctggtcaaca ctacggatga tacttcagct ttttctggta attgaattaa
    18961 tgcgatttgc caaggtgata tggctaaatc atgtaaaaaa tagcgatatt cttcacgtaa
    19021 taggtctaat cgtctaacgg cctctgaaat atttaactga cgaaaatcat aaattttgag
    19081 ttgattcgtc aattcaattt tgggtacaac atattgtacc aatcgcgttt catcaatcat
    19141 ggtacgtaac gcagaataat gcttcaccag tatcgttaaa cgctgtgaaa aaatttcagc
    19201 atcaattttt ccatgcaact cacgaaagtc atgcatagag gattgactca gtgggaacat
    19261 tttactttta cccagtaaat atgctttttg catgggggtt aatggcattt ggtttatcat
    19321 ttttatttcc cctcaatcac ttgtagaaac acagtggcaa tgcgctgtgc ggtatcaggt
    19381 attttttgtt caatcaataa tgcaatattt tttgcattac gctgagtaaa gatatcgacg
    19441 acagagacat cacttttctt gaaatattga ttcagtgcag tgactaaatg tgtagctaat
    19501 aaagagtcac caccttcatc aaagaaatct atatcaacga ttgcctgttg ctgtggtaac
    19561 ccaataattt tagccataat gaaacacacc acgcgctcca gtgcagtgga ttgcaatggt
    19621 tgctgtgatg ccatctgctc tatagacaaa tggggttgga caaaattctg gatatcctga
    19681 ataggcgtat ttgaagtaaa tgcctgcaat tgatcaacga tataagtttg ttcaggaatc
    19741 aagtacacag gaagaatctg atgatatgca gtctgtaatt cggtagatga caacttttga
    19801 tttaactcaa gtaaagcaat gcaatatgat ttttgctgat cattcatcgc gtatattttt
    19861 acattttgca catgcgaaat attttgaatc cgattttcta aatcttgtac agcaacacaa
    19921 tagccattct tgaaaaacaa ctgatgtgac tgctcaatga catacaattg cccttggtga
    19981 tcaaaatatg ctggaaaccg tgtatctatc cattgctcta aattgggatt agattgttga
    20041 tttatattga ggatcaaacg acctaaaacc caatctggac aatctgcacc caattcattc
    20101 aatacacgaa attgtgtttc ttcatttgct tttggaaatt gagacaaaat ctttgcaggt
    20161 aatcttgaat tttgtttttt acgtacatca gattgtactt gaggtaactc aaatttaaat
    20221 ttctcatcaa atgccgaact gcctttagag attaggccat gaatcatctt aatgtaatgc
    20281 tggaacattg cctcaatcac atcaggttga aaagcatgag ttcgaatatc ccagttcaca
    20341 gccaggccat gattgaaata tgcaatttgc acatctaaat caacttttgg gccttgtgaa
    20401 atacaccaga ttggttgccc aagagtgtct tgtagtggct tagaaaaaat ttcaccttca
    20461 tctaaggctg aggtaaaaac aataggtgaa atttccaatt tttgatgatg tctggataaa
    20521 tcacgtaata catgaatacc gccataacga taatgttcaa taatctgatc tacatctcgc
    20581 tcaatacgtt ttgtagtttc tagcaaagtt tcatggttat tcagttttaa gctcagtaaa
    20641 ctcatttggg taaaatcacc cacaatatgg cggatatcat caccatatgg ttcacgaata
    20701 aatgttggta aattaagtct aaagtcagac ctggatgacc aagaagcaat tgtgtacgaa
    20761 aataaagtaa gacaaagact tcgtaccgaa accccatggg tttgtgccag gctttgtaaa
    20821 caggcacgct ctttttcact aaaaatatga attaaacgtt caaagtgatg ttcatcagat
    20881 ctgagaccct ccgcaatttg tggtaactga ggtgctggcg caatattatc aagttgttgt
    20941 tgccaccatg cttgatcttg tcctaatcgg gtttgatact ctacattttg tcgacgttgt
    21001 tcgagataat taaaatattc aatctgatct acagctaact ttggcaaagc cttaccttga
    21061 tataaagcgg ttaggtcttc aacaacgatc aagaaacttt gtggatcaat cgctgacata
    21121 tctgagtcaa tatgaagcac atgacgatgc tcaggtaaca atgttaactg cacatccaaa
    21181 acatggcctt ctgcaccatt taaaagctgg tgagttaaac gctgtcgttt agcatacaaa
    21241 tgtgcttgaa tggctgatgc actcagatgc gttaaatcct caagatgaat atcttgatgc
    21301 tctaatgaca caatactttg ctgtccatta ataattctga cattcaacat tggatggcgt
    21361 tgcactaaag tatgaaatgc tttttgtaag cgaacagtgt ctaaattgac tccttcaaac
    21421 tccatatata aatgtgcaga tacgccttcc gtctcttttc ctgcccaata ggcatattgc
    21481 atatctgata gtggaacaag atcagtgggt aactgctcta accatgtggg tacgtctaat
    21541 gacaactgcg ccgtggattc agatatattt aaatcagcta tatttctatt ttcattggct
    21601 tgaatcaggt catgccaatc ctgaacggta ggtgacatag caaaatctgc ataagacaaa
    21661 gctttgctat atcttttctc aaaatgatcg accaattgca tgatcgctaa ggagtgtaaa
    21721 ccatgttcaa ttaaattatc ttggggttga atatgaacat cttcaacttg aagcacttga
    21781 tgaattttcg cagtaatttc ttgctgtaat tgcattattt tatccttttc ttattgacct
    21841 aaagttgcac caccatcaac cactaaatca tgcatagtga tgtgcgaggc ttggtcacta
    21901 attaagaaca tcacagcatt ggcaatgtct tgtgttagtg caattttctg caatggaata
    21961 cccactttgt attgcgccaa atttccatga atcgtttttt gctccccaga cgcatcattc
    22021 caaagttgac gaagcattgg agtcactgta gaacctggcg atacaatatt cacccgtacg
    22081 ccatattcag caagttccaa agctacagtt ttactaaaac tagttaatgc cgctttggat
    22141 gcaccgtaag ccgccatctc aatgcgtggt acacgtgcag aattggaaga caccatgaca
    22201 atgctacctt cacgtttgtt acgaaaatgt ggacttaaat tctttaaaaa ataaaatgga
    22261 gcaaaggtat tcacttcaaa agtttgtctc caagcctcaa tcggcaatgc atcgtgccca
    22321 tctaaatgca atacccctgc tgtattgatg aaataatctg gtggtgacgt atttaataat
    22381 ttttggcaaa gatcaaaaac ctgtgatgaa tcaccgacat tacattggtg aacttcgtaa
    22441 tggtcacttg tcataaaatt gcgaatagat aaatcgaaac cgacgacata aatattttga
    22501 gcaatcagtt gttgcatgat ctgtgcacct atgccctgat taacaccagt tacccacgca
    22561 attttcttta ctagatttat atctaaaact tctgaattga tctgtgtcat ggtcatcctc
    22621 gagttagctg ttaattctta gccttatgaa gcaatgacac attcaacatc ttcgacaaca
    22681 cccaagttat tctgaacata ttgcaaagcg aacaaatgat cttttaaact aaagtcagca
    22741 actgaatcac cgaccacaaa aggttgaata ccattcataa aggcttctgc agcagtttga
    22801 agcacaccaa tatgcgcata aacaccacaa ataataagtt gatctttttg agtgtcttta
    22861 agcatttttt ctaagtctga attataaaaa gcgctatatc gccatttagt aagcacttga
    22921 tcttgctcat ttggcattag ttttttgaca attgcggcct gctcaggata agccgttaga
    22981 ccaggccccc acatatcatt caacaaagca cgatcttgat ctttttgttc agcaggttgt
    23041 gcggtataaa acactggtac atcattagct acacaccacg cttttatttg tgcgatgtta
    23101 tcaaccacct gttgaatcaa ttctgaatct tcaccgtaga aattgacaaa ataatcttgc
    23161 atgtcatgaa tcaataaagc agcacgattt ttctcaattt tccaattcac ttttgcagcg
    23221 ggataatctt gtttaaatgg aagtggataa cttggaattt ttggaatggt catagtgttg
    23281 cctatatatc gttaatctgt tttcaaaaat atgtctttga tttggttttc atgctctatt
    23341 ggcgccaaat atagaatttg ttttcatcag gaatgaaaag ttgcgcttag ggtttttagt
    23401 agagtttgca ttttgacttc agtttcactc cattcaagtt cagcttgtga tcccatcaca
    23461 attccagcac cagcatataa acgaattttt ttatcattga gtaaaccgca acgaatagtg
    23521 acagcccatt cgccattacc ttgggcatcc atccatccca ccaaaccagc aaaataatga
    23581 cggtcgtaac cctcatgttc taaaataaac tgttttgcag gctcggtagg tgaaccacag
    23641 attgcaggtg taggatgtaa agccaatgcc aactgcaacg cattgtcaga ctgctttttc
    23701 aactgaccat caaatacggt cgaaagatga agcatcgtgg ccgtttttaa aatttcaggt
    23761 ttctctaaaa cctttaattt ttggcaaaat ggctttaaat tttctaagac actgtccacc
    23821 acaatttgat gctcattaag atctttttct gatgcataca attcatgaat acgtgactga
    23881 tttatatttt catcctcact taaaggacga gagcctgcta aaggattact acgaacagtc
    23941 agatcatttt ttgaaatcag taactctgga cttgcaccca gaaggtaagc attgtcttca
    24001 actggaatag caaaactaaa tgcatgtgga ttttctttag ctaatgtatc aaccaaatca
    24061 aaaggatttt gtgactgtga aagttcaaaa tccacagcct gtgacaaaac cactttttcc
    24121 aattgatcac acctaaactg atcaattgca atatcaatgg catgcgcaaa atctttttgt
    24181 ttaatcaaag gtttttgatt tgaaatagat aatggcgaat gagttatttt agatgaaatc
    24241 accaattgtc tttgtttacg atgattccga taaatattga gagacgatgc ttgtgttgta
    24301 tcgaatggaa ttgcaccaac caaaattgga tttgcatttg gatctttttt taatttctga
    24361 aaactatctg taatggtttg acttaatttt tcataatcgc aagcagctaa ttttactact
    24421 tcagctaaat ctgatgctaa taaacgataa tctttagtta aaaaacaaga agattctagg
    24481 ttaatattca gttcaattgc atgatcaatt gagagattca tatcattcat gaagccattc
    24541 cccttgtaat acacgtgtta attcccagtc aataaacaac taaaatttct agtgcatgca
    24601 attgcattaa caataataat attgataatc attaacattt aatagaaaat atccgatgta
    24661 ttttttaaac ttctaggaaa atgactgatt tataagatta aatttctttt aagaagaaac
    24721 tcagtgtgat taaaagattg attagtctac aaataataaa tctaaactta tgaaaaatat
    24781 aagaaatatt aaaaaactcg tgaaattttt ttaataagag taaaagctag aattgttatt
    24841 aatttacgcc tcatacaacc taggactgta atgctcactg attaaaaaaa ttatttagat
    24901 tctcatgtca aactttaact taaatgttga tgatatctat gagggagtgc ctacttccct
    24961 tccgttaaac acaatgctct tgtagtcgat tcatagaatc atatgctcaa acaatcttct
    25021 cagtctgctt ttctggaagt gtttgggtcg tattttttga tagggttata actagaatca
    25081 taagtagatt tatcagtcat gtagtacgaa gggattgaat ttattggcat ataaaaacta
    25141 ttctaattat gcgaattaca aaaactttac aaattgtggt gtgagtcaat catcaatggt
    25201 actggatttt ataaaaatgt tctgcataaa aattggctgc ctaaaatcca tcgaatgaaa
    25261 ttagcgtata atttcaacat acattgctaa caactgtagc tgaaataacg ttcataaatt
    25321 tttttaaaat actgagtact actgtatcca atttgattgg caactttttc aattgaaaca
    25381 ccctctttga gcaaaatttg agcacatctc attcgatttt ctaataaata gtgtccaata
    25441 gttttgcccg tatattcctt aaatattttt tttaaatcac actcattaat cccgacttgt
    25501 ttagccagag tgcgaattgt gatctttttt tcaaattcat tttctaaaat aaagatcgtt
    25561 ctttgaactg atgaaggtat ttcgttagat ttttgattgt tacctagcaa tagactcatt
    25621 aactctagtg ctgccccctc caagtgaaga agatcaattg atgactgagc tgatggaata
    25681 ttgagtaaat agtgggcttg atgtaataca ttcttattag gaatattgat cgtttttaat
    25741 gctgtacttg gttcacttaa aaagaaattt gcgaaatcag aatttagaga attactttcc
    25801 ataatttcaa ggaaactttg attaaaatct aaagaaatta gagacatttc tttatgctct
    25861 tgaaggtgaa ttgtttgtaa gcctaaactt ccttttcgta aaataatcat aggggaacga
    25921 atttcatatt tatgattact tttatgattt tgaatgtgat gtgttccaga aaggagtatc
    25981 gtgatcccaa aggaatgagc tggtgtctca gcactcatct gaagtggatg atctatccaa
    26041 tattttcctt tacctacgca caatttacca aaatcataaa tttcactata gccatttcca
    26101 tcagacggat tgaaatgatt caaatgatgg ttgggtaagg gagaacatga gtctaaaaat
    26161 atatcgccca cttgtttcaa tacgacctta tgagaatcaa tataaataga cattttaaaa
    26221 gctccgctca c
//
