LOCUS       BGC0000356             27708 bp    DNA     linear   PLN 10-APR-2009
DEFINITION  Aspergillus fumigatus DNA, fumitremorgin biosynthetic gene cluster
            (ftmA, ftmC, ftmD, ftmB/ftmPT1, ftmE, ftmF, ftmG, ftmH, ftmI),
            complete cds.
ACCESSION   BGC0000356
VERSION     BGC0000356
KEYWORDS    .
SOURCE      Aspergillus fumigatus
  ORGANISM  Aspergillus fumigatus
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae;
            Aspergillus; Aspergillus subgen. Fumigati.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:38:50
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..27708
                     /db_xref="taxon:746128"
                     /mol_type="genomic DNA"
                     /organism="Aspergillus fumigatus"
                     /strain="BM939"
     cand_cluster    1..27708
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="indole"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..27708
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000356"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..27708
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="indole"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..26956
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[320:6956]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      321..6956
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..26956
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     gene            complement(321..6956)
                     /gene="ftmA"
     CDS             complement(321..6956)
                     /NRPS_PKS="Domain: AMP-binding (54-457). E-value: 5.9e-83.
                     Score: 270.5. Matches aSDomain:
                     nrpspksdomains_ftmA_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (599-658). E-value: 2.8e-13. Score:
                     41.7. Matches aSDomain: nrpspksdomains_ftmA_PCP.1"
                     /NRPS_PKS="Domain: Condensation_DCL (709-975). E-value:
                     3.2e-42. Score: 136.5. Matches aSDomain:
                     nrpspksdomains_ftmA_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1148-1548). E-value: 2e-83.
                     Score: 272.1. Matches aSDomain:
                     nrpspksdomains_ftmA_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1682-1747). E-value: 2.1e-15.
                     Score: 48.6. Matches aSDomain: nrpspksdomains_ftmA_PCP.2"
                     /NRPS_PKS="Domain: Condensation_DCL (1814-2069). E-value:
                     2.2e-21. Score: 68.1. Matches aSDomain:
                     nrpspksdomains_ftmA_Condensation_DCL.2"
                     /codon_start=1
                     /gene="ftmA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     250.7; E-value: 3.9e-76)"
                     /gene_kind="biosynthetic"
                     /product="nonribosomal peptide synthetase"
                     /protein_id="BAH23995.1"
                     /sec_met_domain="Condensation (E-value: 5.4e-39, bitscore:
                     123.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 4.8e-90, bitscore:
                     291.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.1e-11, bitscore:
                     31.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MAMALAVGAPSEQRGNLPYNTLKDGPTVDSMKATTDGKNGQGESA
                     FWDTCVHTVFREHCQRAPNSPAVNAWDGSFTYAELDSLSDAIASVLILSGVGPESIIPI
                     YMQKSRWTTVAILGVLKSGGAFTLLDPSHPRSRVEEISKEIQARFILTSEKLSKQCLEM
                     FSVLVVEHLSRACLPSPGQAGHTRSRPENAAYIAFTSGSTGKPKGIVIEHRSYCSGARS
                     HLKVFGIDSTSRVLQFASYAFDVSIMETLSTLMAGGCLCVMSESERSDPNLFVVSYKNL
                     RISHCFMTPSFARTVPWTECCNPPPTLIVGGELMRPSDARAYKEMGIRCMNAYGPAECS
                     VNVSVQSRVEAAVDPRNIGYTTGATAWIISPENPEELMPTGTVGELLVEGPIVGRGYLN
                     DPKATRQAFIDTPAWLRRHRKGTSYQHRVYRTGDLASLDSITGALLLHGRKDAQVKIRG
                     QRVELPDIEHHLQLTLPNDNAEVIVEKVTFSDDGSEKLIAFVLVRPSNTDSVIGNTGDR
                     LFLAPQSQIMEQFAISKKHLQTHLPSYMVPDIFIPISTLPQTASGKTDRKALRTRAAAL
                     SRRDVQCFLLSPAGGKRPPSTPKEATIRSLYSNVLNLPIDLIGMDDTFLRLGGDSLQAI
                     RLVAAARAAGLILHAKDILSSQSTLAEQSKRAGLIQTIDRTWESSPPFALLHGPTRHAI
                     VDLAQKQCRVPSNLIEDIYPCTALQEGMFITSLKHPGMYTGQIIFDIPDRMELPRLKAA
                     WLSVVSENAALRTRIIETHEGLMQAVIVDDFVWEEETDEMLLSSDGEALEITKIGVPLV
                     RFRYRPRHRQLMMTIHHSIWDGWSLRLVHEQLQRAYIGRDLLPSTSYRSFIQYTQELPG
                     ADEFWASELAGVNAPIFPTLPSGNYRPRVNASHRHVVRNLASTGKEEHTAATYIHLAWS
                     LLVAHYTDADETVYGVTVNGRSADVPGIENIVGPTIATVPTRIRVNEEDTVEMALDHVQ
                     DALARMIPYEQAGLQRISRCSRDASEACRFQNLLIIEAPTDSDVDCEKNEAGNFSIIGG
                     TTQTGMDYTAFSSYAMMLVFRTSANKSAISFDITYDAQVIGHDEVERMAHQFEHVLRHI
                     YTLATGRIGDISFIGPRDIEQVQQWNSSMPPADNRFLQELIFAQCSRRPQASAIISWDG
                     SWTYRELWAHSSFFARQLQRYGVTRGTPVAVCLDRSRWSIAVILGVLLARGTCVLIDLL
                     APRQRVRDILQIAGTGILVHSHATATLTSGLCPTVINVSFLAAQSDSSQPEFPFTLETW
                     GGTPEDLAFIIFTSGSTGHPKGIEMPHRTLSTSISHHSAGMRVTSSSRVLHFSSYAFDV
                     SIYEIFTTLAAGGTICVPSEFDRMNNLAGFIQDTQVNWAFLTPSTARSLNPADVPLLTT
                     LVLGGEAVTHESVEVWAKGRSLINGYGPAEATICGVGNIPEAGWKSGVVGRIIGGLGWV
                     TVPSDPNRLAAVGAVGELLLEGPFLARGYLNLPEVTKAAFIDPPSWRTRIPAPSPYSFL
                     YRTGDLVRYQPDGSIQYVGRKDSRVKLRGQLVDLGAVEASVMRVYPAAGQVVADVLVSE
                     NTARLIAMVKLGPSVTENHDGPMFAAPDLVFNEAAASIQARLRAIVPAYMVPSMFIPLR
                     HIPRTLTGKTDRRRLRDKILSLSHSDLQRYMMSSSTKTPMSDDNERRLQEIWAEVLQLP
                     CEAIGREDSFLSLGGESLATMKMVALARRVGFMFAVTDVMNNTSLSTLARSRHLITEQA
                     ILTSSPSLSLPTIEGESLQEILRPLLNAGHIQGGNDIAAIHPVTAAQAFLVQRYPWSHF
                     QFDLSGAVSPSKLQTACTALMARFTILRTVFVEHAGCLLQLVLREVPNRVHEITTNEPL
                     DDFCNSVCQQQQDVCVVNSTTLPTLFTLVSNRQLNRHRLLLRLAHAQYDLTTIPLIVQS
                     LADEYNRTLRSGFSADFGYYLSHHKRQNNDDRSHNFWKRYLSGSSMMSTNQTADPTTVQ
                     ERVFHVTGSCIIIPTSHPPDITIATAVKAAVCLVLAARTGCTDIVIGQTVDARCSSADS
                     TLDQIVGPCTNYIPYRLSVCCSKTALEYLRSAQAQHTTCLRYSSLDLDQIVAKCTSWPS
                     STQFGYIVQHQDTGAELALTLGGDTTSLPMTSYGRVFPQGEVWIGSTPCSTGLRIDVIA
                     LSAVLSQKDAQTMAEEVGAALEKLLGCGYRRLSHLIGNTFAT"
     aSDomain        complement(750..1514)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_Condensation_DCL.2"
                     /domain_subtype="Condensation_DCL"
                     /evalue="2.20E-21"
                     /label="ftmA_Condensation_DCL.2"
                     /locus_tag="ftmA"
                     /protein_end="2069"
                     /protein_start="1814"
                     /score="68.1"
                     /tool="antismash"
                     /translation="FQFDLSGAVSPSKLQTACTALMARFTILRTVFVEHAGCLLQLVLR
                     EVPNRVHEITTNEPLDDFCNSVCQQQQDVCVVNSTTLPTLFTLVSNRQLNRHRLLLRLA
                     HAQYDLTTIPLIVQSLADEYNRTLRSGFSADFGYYLSHHKRQNNDDRSHNFWKRYLSGS
                     SMMSTNQTADPTTVQERVFHVTGSCIIIPTSHPPDITIATAVKAAVCLVLAARTGCTDI
                     VIGQTVDARCSSADSTLDQIVGPCTNYIPYRLS"
     CDS_motif       complement(1416..1508)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0014"
                     /evalue="3.20E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ftmA"
                     /protein_end="1847"
                     /protein_start="1816"
                     /score="16.3"
                     /tool="antismash"
                     /translation="FDLSGAVSPSKLQTACTALMARFTILRTVFV"
     aSDomain        complement(1716..1910)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_PCP.2"
                     /evalue="2.10E-15"
                     /label="ftmA_PCP.2"
                     /locus_tag="ftmA"
                     /protein_end="1747"
                     /protein_start="1682"
                     /score="48.6"
                     /tool="antismash"
                     /translation="ERRLQEIWAEVLQLPCEAIGREDSFLSLGGESLATMKMVALARRV
                     GFMFAVTDVMNNTSLSTLAR"
     aSModule        1716..4829
                     /complete
                     /domains="nrpspksdomains_ftmA_Condensation_DCL.1"
                     /domains="nrpspksdomains_ftmA_AMP-binding.2"
                     /domains="nrpspksdomains_ftmA_PCP.2"
                     /locus_tags="ftmA"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(2283..2348)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0013"
                     /evalue="9.10E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="ftmA"
                     /protein_end="1558"
                     /protein_start="1536"
                     /score="21.4"
                     /tool="antismash"
                     /translation="YVGRKDSRVKLRGQLVDLGAVE"
     aSDomain        complement(2313..3512)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_AMP-binding.2"
                     /evalue="2.00E-83"
                     /label="ftmA_AMP-binding.2"
                     /locus_tag="ftmA"
                     /protein_end="1548"
                     /protein_start="1148"
                     /score="272.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FAQCSRRPQASAIISWDGSWTYRELWAHSSFFARQLQRYGVTRGT
                     PVAVCLDRSRWSIAVILGVLLARGTCVLIDLLAPRQRVRDILQIAGTGILVHSHATATL
                     TSGLCPTVINVSFLAAQSDSSQPEFPFTLETWGGTPEDLAFIIFTSGSTGHPKGIEMPH
                     RTLSTSISHHSAGMRVTSSSRVLHFSSYAFDVSIYEIFTTLAAGGTICVPSEFDRMNNL
                     AGFIQDTQVNWAFLTPSTARSLNPADVPLLTTLVLGGEAVTHESVEVWAKGRSLINGYG
                     PAEATICGVGNIPEAGWKSGVVGRIIGGLGWVTVPSDPNRLAAVGAVGELLLEGPFLAR
                     GYLNLPEVTKAAFIDPPSWRTRIPAPSPYSFLYRTGDLVRYQPDGSIQYVGRKDSRVKL
                     R"
     CDS_motif       complement(2454..2540)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0012"
                     /evalue="1.50E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ftmA"
                     /protein_end="1501"
                     /protein_start="1472"
                     /score="39.7"
                     /tool="antismash"
                     /translation="VGAVGELLLEGPFLARGYLNLPEVTKAAF"
     CDS_motif       complement(2649..2675)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0011"
                     /evalue="1.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ftmA"
                     /protein_end="1436"
                     /protein_start="1427"
                     /score="5.7"
                     /tool="antismash"
                     /translation="YGPAEATIC"
     CDS_motif       complement(3024..3083)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0010"
                     /evalue="2.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ftmA"
                     /protein_end="1311"
                     /protein_start="1291"
                     /score="23.1"
                     /tool="antismash"
                     /translation="AFIIFTSGSTGHPKGIEMPH"
     protocluster    3039..27708
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[13038:22997]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13039..22997
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
     cand_cluster    3039..27708
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="2"
                     /tool="antismash"
     CDS_motif       complement(3288..3329)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0009"
                     /evalue="3.80E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="ftmA"
                     /protein_end="1223"
                     /protein_start="1209"
                     /score="1.9"
                     /tool="antismash"
                     /translation="LGVLLARGTCVLID"
     aSDomain        complement(4032..4829)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_Condensation_DCL.1"
                     /domain_subtype="Condensation_DCL"
                     /evalue="3.20E-42"
                     /label="ftmA_Condensation_DCL.1"
                     /locus_tag="ftmA"
                     /protein_end="975"
                     /protein_start="709"
                     /score="136.5"
                     /tool="antismash"
                     /translation="EDIYPCTALQEGMFITSLKHPGMYTGQIIFDIPDRMELPRLKAAW
                     LSVVSENAALRTRIIETHEGLMQAVIVDDFVWEEETDEMLLSSDGEALEITKIGVPLVR
                     FRYRPRHRQLMMTIHHSIWDGWSLRLVHEQLQRAYIGRDLLPSTSYRSFIQYTQELPGA
                     DEFWASELAGVNAPIFPTLPSGNYRPRVNASHRHVVRNLASTGKEEHTAATYIHLAWSL
                     LVAHYTDADETVYGVTVNGRSADVPGIENIVGPTIATVPTRIRV"
     CDS_motif       complement(4041..4130)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0008"
                     /evalue="3.30E-12"
                     /label="C5_DCL_263-294"
                     /locus_tag="ftmA"
                     /protein_end="972"
                     /protein_start="942"
                     /score="38.8"
                     /tool="antismash"
                     /translation="VYGVTVNGRSADVPGIENIVGPTIATVPTR"
     CDS_motif       complement(4413..4478)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0007"
                     /evalue="3.50E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="ftmA"
                     /protein_end="848"
                     /protein_start="826"
                     /score="19.7"
                     /tool="antismash"
                     /translation="IHHSIWDGWSLRLVHEQLQRAY"
     CDS_motif       complement(4650..4766)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0006"
                     /evalue="2.00E-05"
                     /label="C2_DCL_024-062"
                     /locus_tag="ftmA"
                     /protein_end="769"
                     /protein_start="730"
                     /score="16.9"
                     /tool="antismash"
                     /translation="GMYTGQIIFDIPDRMELPRLKAAWLSVVSENAALRTRII"
     aSDomain        complement(4983..5159)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_PCP.1"
                     /evalue="2.80E-13"
                     /label="ftmA_PCP.1"
                     /locus_tag="ftmA"
                     /protein_end="658"
                     /protein_start="599"
                     /score="41.7"
                     /tool="antismash"
                     /translation="EATIRSLYSNVLNLPIDLIGMDDTFLRLGGDSLQAIRLVAAARAA
                     GLILHAKDILSSQS"
     aSModule        4983..6794
                     /complete
                     /domains="nrpspksdomains_ftmA_AMP-binding.1"
                     /domains="nrpspksdomains_ftmA_PCP.1"
                     /locus_tags="ftmA"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5556..5618)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0005"
                     /evalue="1.70E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ftmA"
                     /protein_end="467"
                     /protein_start="446"
                     /score="29.8"
                     /tool="antismash"
                     /translation="HGRKDAQVKIRGQRVELPDIE"
     aSDomain        complement(5586..6794)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ftmA_AMP-binding.1"
                     /evalue="5.90E-83"
                     /label="ftmA_AMP-binding.1"
                     /locus_tag="ftmA"
                     /protein_end="457"
                     /protein_start="54"
                     /score="270.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FREHCQRAPNSPAVNAWDGSFTYAELDSLSDAIASVLILSGVGPE
                     SIIPIYMQKSRWTTVAILGVLKSGGAFTLLDPSHPRSRVEEISKEIQARFILTSEKLSK
                     QCLEMFSVLVVEHLSRACLPSPGQAGHTRSRPENAAYIAFTSGSTGKPKGIVIEHRSYC
                     SGARSHLKVFGIDSTSRVLQFASYAFDVSIMETLSTLMAGGCLCVMSESERSDPNLFVV
                     SYKNLRISHCFMTPSFARTVPWTECCNPPPTLIVGGELMRPSDARAYKEMGIRCMNAYG
                     PAECSVNVSVQSRVEAAVDPRNIGYTTGATAWIISPENPEELMPTGTVGELLVEGPIVG
                     RGYLNDPKATRQAFIDTPAWLRRHRKGTSYQHRVYRTGDLASLDSITGALLLHGRKDAQ
                     VKIR"
     CDS_motif       complement(5733..5822)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0004"
                     /evalue="4.90E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ftmA"
                     /protein_end="408"
                     /protein_start="378"
                     /score="41.2"
                     /tool="antismash"
                     /translation="PTGTVGELLVEGPIVGRGYLNDPKATRQAF"
     CDS_motif       complement(5934..5957)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0003"
                     /evalue="2.90E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ftmA"
                     /protein_end="341"
                     /protein_start="333"
                     /score="4.6"
                     /tool="antismash"
                     /translation="YGPAECSV"
     CDS_motif       complement(6318..6377)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0002"
                     /evalue="2.00E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ftmA"
                     /protein_end="213"
                     /protein_start="193"
                     /score="29.5"
                     /tool="antismash"
                     /translation="AYIAFTSGSTGKPKGIVIEH"
     CDS_motif       complement(6567..6608)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ftmA_0001"
                     /evalue="2.40E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="ftmA"
                     /protein_end="130"
                     /protein_start="116"
                     /score="8.5"
                     /tool="antismash"
                     /translation="LGVLKSGGAFTLLD"
     gene            complement(8500..10454)
                     /gene="ftmC"
     CDS             complement(join(8500..8687,8757..8858,8930..9228,
                     9301..9422,9486..10454))
                     /codon_start=1
                     /gene="ftmC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 300.5; E-value: 3.6e-91)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="BAH23996.1"
                     /sec_met_domain="p450 (E-value: 2e-64, bitscore: 207.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MKPSHSDTPLMMPSVMKCGYLATAGLIGICTHLSYFRYGEHHLYP
                     WRYVRFHLCLTMGVAALLYAKKPPQYTLCSMDLVKDVSLLMATYLVGLFASLLLYRTLF
                     HPLRQIRGPWAAKISSFWLSFRLRRGPSFRILHELHEEYGPVVRVGPSEVSIIHPEAVR
                     MIYGPNSRCSKNTFYDNGHPMMSLHSYRDRIAHDQRRRVWSAGFGDRALRGYEQRMRVY
                     RQKLFQRLEARAVAESAINISQWFNFYSYDTMGDLAFARSFDMLDASRNHWAVDMLMHG
                     MIGYRYLFPSWFFRLLATMPSLSSDWHKFIGFATDTMLRRVGEQVDVPDIFASLLAPLN
                     GREPTEDERNMLMGDAMLIITAGSDTTATSLTSIVYELARHLDEVDKLRAELDPIEADS
                     DGEYQHDTLAKLPHLNGFINETLRLHPPIPGVIPRKTPPEGIHVKDVFIPGNMTVFSPQ
                     WSMGRSEAAYIDPEIFNPERWYKHMDLVKDPSAFAPFSIGPYSCIGKPLALMNIRTTVA
                     RLIMSFDVRFPEGEDGIRWMDAADEHFAMGIHQMPVVLTRRH"
     gene            11206..12319
                     /gene="ftmD"
     CDS             join(11206..11733,11819..12319)
                     /codon_start=1
                     /gene="ftmD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 254.4; E-value:
                     2.7e-77)"
                     /gene_kind="biosynthetic-additional"
                     /product="O-methyltransferase"
                     /protein_id="BAH23997.1"
                     /transl_table=1
                     /translation="MTQAVDIGTIQTLIRLEVPDQVPLTGSIPYDALVKKLKTPVDPEL
                     LQRLIRFTRLVGFLDEDAEGAVKHSPMSAIFVNDPDTAGQARFMADFGIRPCSFIYESI
                     KLDPSGEAARQGPLALMAREPGAREGPTFFEVLEKDPVNRKRWHDGMAVHNDSMVRHVA
                     GAYDWGTVQSLVDIGGSEGHVAAVIVNAFPHIQITVQDRPEIIEKARQRGDRHPNIIFE
                     EHDFFTPQPRIADAYFLRLILHDWNDADCTRIVRQISSALRPGARLLIMDAVLPEPGEG
                     SLQSERRLRRSDIGMYTLFSAKERSLAQMRRLVEDCDSRLRFEKLYTPPGSHASMLSWI
                     CE"
     gene            13039..14502
                     /gene="ftmB/ftmPT1"
     CDS             join(13039..14300,14370..14502)
                     /codon_start=1
                     /gene="ftmB_ftmPT1"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /product="prenyltransferase"
                     /protein_id="BAH23998.1"
                     /sec_met_domain="dmat (E-value: 1.2e-103, bitscore: 336.6,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MPPAPPDQKPCHQLQPAPYRALSESILFGSVDEERWWHSTAPILS
                     RLLISSNYDVDVQYKYLSLYRHLVLPALGPYPQRDPETGIIATQWRSGMVLTGLPIEFS
                     NNVARALIRIGVDPVTADSGTAQDPFNTTRPKVYLETAARLLPGVDLTRFYEFETELVI
                     TKAEEAVLQANPDLFRSPWKSQILTAMDLQKSGTVLVKAYFYPQPKSAVTGRSTEDLLV
                     NAIRKVDREGRFETQLANLQRYIERRRRGLHVPGVTADKPPATAADKAFDACSFFPHFL
                     STDLVEPGKSRVKFYASERHVNLQMVEDIWTFGGLRRDPDALRGLELLRHFWADIQMRE
                     GYYTMPRGFCELGKSSAGFEAPMMFHFHLDGSQSPFPDPQMYVCVFGMNSRKLVEGLTT
                     FYRRVGWEEMASHYQGNFLANYPDEDFEKAAHLCAYVSFAYKNGGAYVTLYNHSFNPVG
                     DVSFPN"
     gene            complement(14683..16263)
                     /gene="ftmE"
     CDS             complement(14683..16263)
                     /codon_start=1
                     /gene="ftmE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 168.9; E-value: 3.2e-51)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="BAH23999.1"
                     /sec_met_domain="p450 (E-value: 3e-57, bitscore: 183.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MERLPLSPAVLFLIIVLPILYLWIRYTAPARPHGKHLSLPPGPPR
                     LPKIGNLHQVPRQIPWKKYKEWSDTYGPIMSVQLADTIAVVFSSWDLIKNHIERRNTIY
                     SSRPSVPFFLHATGGLNASILPYGPEWKLQRAIRSSVLKPSMTVKYRDVQHVETTQLLH
                     ELLSTNDFPVCLRRCIASVFLTVAYGERCVDHAGLEAIDRLEELNRAIALHAEALFSGA
                     AGILTQLVLPKALVDRLPVRWKKDADMLHNRLTADLVARTRAALVRPGWNWVKEFSMKD
                     GIGSGDGDGEQGSKVELKRLAYMVGSLYEASMAASQALRVIILAGLLHPDATRRMHDEL
                     DAVVGTGRLPDFHDAAQLPYTQAFIKEAMRWRSLTPMGSPRATSDEDECRGYHIPCGAT
                     VLVNVWAINHDEAIFLDPFAFQPERWIENPDLPQLMYGMGQRACPGRHMGQDSLFLATA
                     RLFWAFDMALPDGADPIDQERFLDSGTTLAAFLPDFEVRFTPRSEKYQEVIENSMAVLP
                     DVLSISATP"
     gene            complement(17139..18014)
                     /gene="ftmF"
     CDS             complement(17139..18014)
                     /codon_start=1
                     /gene="ftmF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /product="alpha-ketoglutarate dioxygenase"
                     /protein_id="BAH24000.1"
                     /sec_met_domain="PhyH (E-value: 6.2e-23, bitscore: 71.4,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTVDSKPQLQRLAADADVDRMCRLLEEDGAFILKGLLPFDVVESF
                     NRELDVQMAIPPPKGERLLADKYPPHFKYVPNVATTCPTFRNTILINPVIHAICEAYFQ
                     RTGDYWLSAAFLREIESGMPAQPFHRDDATHPLMHYQPLEAPPISLSVIFPLTEFTEEN
                     GATEVILGSHRWTEVGTPERDQAVLATMDPGDVLIVRQRVVHAGGGNRTTAGKPRRVVL
                     AYFNSVQLTPFETYRTMPREMVESMTVLGQRMLGWRTMKPSDPNIVGINLIDDKRLENV
                     LQLKAADSPA"
     gene            complement(19109..20921)
                     /gene="ftmG"
     CDS             complement(join(19109..19539,19609..20199,20250..20318,
                     20372..20471,20533..20649,20715..20921))
                     /codon_start=1
                     /gene="ftmG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 130.7; E-value: 1.2e-39)"
                     /gene_kind="biosynthetic-additional"
                     /product="cytochrome P450"
                     /protein_id="BAH24001.1"
                     /sec_met_domain="p450 (E-value: 3.8e-43, bitscore: 137.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="METLDAIQLPYLGVVGASLIVILGIILLFPLGSDPFITINQHPRD
                     LFQTKAKQQFEYNAAALLNEGLQTGHSAFRLVTNMVTYLILKDQYAEEIKNDSRFGAHE
                     AVDPVLLVDLPGLESMFQGSLHNQVPPMAVRALNKELVHLTPSLSEEAMNCLQTRWTDS
                     TEWHGVSIPETVLALIAQMTTRALLGPELCRNPEWLDIAKSFTTNRAIAVAAVQSWPSF
                     LQPVIHWFLPPCRALRRQIQCARNIILPALERERRAYCSDQPTKREFSNLVFIDQYAKG
                     ARYDATMAQLRIIAVAFQTTSDLVEKVIARLCKHPELIEPLREEVVSVVGNRGLHRHSL
                     RKLTLMESVMKETQRLEPAVIIGMFRLAKEKVTLKDGTVVPKGTNIAFANDLRFDPEMY
                     LEPETFDGYRFQRMREDPAKIDLAPFTKTRMSHLAFGHGKHACPGRFLACDEAKLILCH
                     ILLNYDIRAVEGSPPELRARGMFVQLDPGAMMSVRRRRGTETAPHG"
     gene            21649..22997
                     /gene="ftmH"
     CDS             join(21649..22829,22895..22997)
                     /codon_start=1
                     /gene="ftmH"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     dmat"
                     /gene_kind="biosynthetic"
                     /product="prenyltransferase"
                     /protein_id="BAH24002.1"
                     /sec_met_domain="dmat (E-value: 2.5e-124, bitscore: 404.7,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MTIPTEISCPEEDAFQLLDKFSWFPSDDQRRWWEYTGPYLLKLLR
                     DAKYPQKDQVPCLYLLQQLLVPYLGTFPVVGQAPLPWWSNVTTYGVPFELSWNLLHNIV
                     RIGFEPLSHLAESGVDAFNKTAPEECVSRLACLDNTIDLARFRHFQHHLLVTPEEETWL
                     LREKAPLPKSGRGQQTLAVEFQNGGISAKAYFFPGMKSLATGLSPGKLILDSIERLALP
                     GLKEPVHHLRSTLGLQDDGHPTDTAIAPFLLGVDLCTPERSRLKFYVTDQVVSWDRVAD
                     MWTLRGKRLEDPQCADGLALLRKLWDLLAIPEGYRSNIRPDFAFGTPPPEDYRPVMMAN
                     WTLSPKKKFPDPQIYLLTVGMNDAVVMDALVAFYEVLGWTDLASTYKDKVASYFPGPDF
                     TKTNYIHSGVSFSYRHSKPYLSVYYSPF"
     gene            complement(23314..25356)
                     /gene="ftmI"
     CDS             complement(23314..25356)
                     /codon_start=1
                     /gene="ftmI"
                     /product="ankyrin repeat protein"
                     /protein_id="BAH24003.1"
                     /transl_table=1
                     /translation="MGRWWGLPLPPEIILELFEYLRPPDVVALAQAAEGFAQLALSVYS
                     SSLREEGQTILFSAVTCGHVSIVRHYLEQGADPCAADDEGYTPLHWAAAYGHYNVVSLL
                     IDVGADINARQNSGFSPLDYAIITGHDRVVEVLLKHGATITDVTIGPSQRTTLHAAAIK
                     GYSKIAKMLLSHGAPTDVKDAHGHTPLHLAVSKGHLEIVQALLCAGATVDIQDKVGDSP
                     LHLAAGNGYFAIVQELLNKGADPSLQGRKNATPLHQASLMGFVDVVQLLLESGANVSAQ
                     RSDGQTPLLQASGAGQVATVRLLLGAGSSPSIPDEDGNTPLHFAVLSEKATIAEMLIEA
                     GAHVDSANDKNQTPLHWAAKGHEEMVPTLLKHKADTHARSHTGWTPLHWAANEGHVGIT
                     TALLDAGALDQIQNEHGESALHLAVQKGHQAVVQLLIQRGSKPHLTDNKLRTVLHYAAD
                     VGHEDVVRILLSVQARSDVKDINGRTPLYYAALQGHVVIAKLLLEFGTALDESVKEAFL
                     EAAEAGHELMVQLLITHGIDLSFKDTSGSTALHRAVLGGQIEVVELLLDTEADTSARDN
                     SGKTALHLAAQEGEDEIAKVLLRNSEIRDLQDCDGWTALHWAVNNEHENTVQSLLDAGV
                     DPGIASFDACTPLDLAEVGALETIEQMLREALAATDRPTIGDAPP"
ORIGIN
        1 tgtaagatgt ctcgaaggcc acattcctgg taggttgttg ttgatgatct acccgaggat
       61 cttcttcaac agctactcaa caaaggatgt gtaagtgata aacctgccta cagtcccctg
      121 gtcgtcaagc cactgaagct gatttgattt cccaatcaat agtacctgcg ccctggtgat
      181 aattaatttt cagtcttcag ttttcagacc ttggactagt cactataaca tttaggatat
      241 gtagtgaaga tataaaaata ttccttttat tttatattag agaagatcag gattcgtcag
      301 tgtacaccta gtcactaagt ttaggtagcg aaggtatttc ctatcagatg cgaaagacgg
      361 cgataaccgc acccaagcaa tttctccaac gccgcgccga cctcctcagc catagtctga
      421 gcgtccttct ggcttagcac tgcgctcaga gcaatgacat caattctcag accagtagaa
      481 cagggtgtcg aaccgatcca gacctcaccc tgaggaaata cacggccgta agaagtcatc
      541 ggcaaggaag tagtgtcacc tcccagcgtg agagccaact ctgcgccagt gtcctggtgc
      601 tggacgatat atccaaattg agtactgctt ggccagctgg tgcacttggc cacgatctgg
      661 tcgaggtcca gggaagagta tcggaggcat gttgtgtgct gggcttgcgc gctgcggagg
      721 tattccagcg cagttttaga acagcacacg ctgagccggt acgggatata gttcgtgcag
      781 gggccaacaa tttggtcaag agtgctgtca gccgaactac accgggcgtc cactgtttga
      841 ccgatgacga tatctgtgca gccagtcctt gcggctagaa ccaggcagac ggcggctttc
      901 acggcggtgg caattgttat gtccggggga tgtgatgtgg gtataattat acatgatcct
      961 gtgacgtgaa atacgcgctc ttgaaccgtc gtcggatctg cagtctgatt cgtagacatc
     1021 atagaggagc ctgacaggta tcgcttccag aagttatgag acctgtcgtc gttattctgc
     1081 cgcttatgat gactgagata gtagccgaag tcggcggaga aacccgaacg gagggttctg
     1141 ttgtattcgt cggccaagga ttggacaatt agagggattg tggtgagatc gtactgtgca
     1201 tgagcgaggc ggagcagaag tcgatgtctg tttagttggc ggttggacac gagagtaaac
     1261 agagttggca gggttgtaga gttaacaaca cagacatcct gctgctgctg acaaactgaa
     1321 ttgcagaagt catcaagagg ctcattggtc gtaatctcat ggacacgatt gggcacctcc
     1381 cgcaagacaa gctgcaagag acagcccgca tgttcgacaa ataccgtgcg aaggatagta
     1441 aatcgggcca tcagcgcggt gcaggcggtt tggagcttgc tgggcgagac agcgccagac
     1501 aagtcaaact ggaaatggga ccacggatac ctctgtacga ggaatgcttg tgcagcggtg
     1561 acaggatgaa tagcagcaat gtcattgcct ccttggatgt ggccggcgtt cagtaatggc
     1621 cgaagaatct cctggaggga ctcgccttca atggttggca gtgagagaga gggtgaggag
     1681 gtcagaatgg cctgctctgt gatcaagtgc cgtgaccgcg caagggttga caggctcgtg
     1741 ttattcataa cgtctgtcac agcaaacatg aacccaaccc tccttgccaa tgctaccatt
     1801 ttcatcgtcg ccagagattc accaccaaga gataggaaag aatcctctct cccaattgct
     1861 tcgcatggga gctgaagcac ctctgcccaa atctcttgaa gcctccgttc attgtcatca
     1921 gacatgggtg tcttggtcga ggagctcatc atgtagcgtt ggaggtcgct atgtgataat
     1981 gagagtattt tgtctcggag ccgacgacga tccgtcttgc ctgtgagggt gcgagggatg
     2041 tgccgtagag gaatgaacat ggacggcacc atataagcag gtacaatggc ccgaagacga
     2101 gcctggatag aggcagcagc ctcgttgaaa accaagtctg gggccgcaaa catagggcca
     2161 tcgtggttct cagtcactga ggggccgagc ttcaccatcg caatcagtct ggcagtattc
     2221 tctgagacca acacgtctgc gactacctga cccgcagccg gatacactct catgacactg
     2281 gcctcgactg cacccagatc gacaagctga cctcgaagtt tgacacggct gtctttacga
     2341 ccgacatact gaatggatcc gtccggctga tatcggacca ggtcgcctgt tcggtagagg
     2401 aaagaatagg gcgacggagc aggaatccgt gttctccagc taggaggatc aatgaaagcg
     2461 gccttcgtga cctctggcag gttcaggtat cctcgggcca gaaacgggcc ttcgaggaga
     2521 agttcaccca cggcgccaac cgctgccagt ctgttcgggt ctgatggcac agtaacccag
     2581 cccaaaccac caatgattcg accgacaacg ccggatttcc atcccgcttc ggggatattg
     2641 cccactccgc agatcgttgc ctcggcaggg ccatagccgt tgatgaggga gcggcctttt
     2701 gcccacacct caacgctctc gtgggtcaca gcctcacctc ccagaactag tgtagttagc
     2761 aagggaacgt ctgcggggtt gaggcttcta gccgtggaag gcgttaaaaa cgcccagttg
     2821 acttgggtgt cttgaataaa gcctgcgaga ttgttcatgc ggtcaaactc ggaggggacg
     2881 cagatggttc caccagcagc caatgtggtg aagatttcat agatgctcac gtcgaatgcg
     2941 tatgaggaaa aatgcaggac acgactgctg gatgtaactc tcatccccgc gctgtgatgg
     3001 gaaatgctcg tcgagagtgt gcgatggggc atctcaatgc ctttgggatg accggtacta
     3061 ccggacgtaa agatgataaa tgcgaggtct tccggggttc cgccccaggt ctccaaagtg
     3121 aagggaaatt ccggctgcga agagtcgctc tgggccgcaa ggaaggatac attgataaca
     3181 gtgggacaga gaccggacgt cagcgtggca gttgcatgac tgtggaccaa gatacctgtg
     3241 ccggcgatct gaaggatatc tcgcaccctt tgtcgcggag ccagtaaatc gatcagcacg
     3301 catgtgcctc tagcgaggag aacgcccagg atgactgcaa tgctccacct gctgcggtcc
     3361 aggcagacag ctacaggagt tcctcgggtc accccatacc tctgtagttg ccgggcaaag
     3421 aacgatgagt gtgcccagag ttcccgatac gtccatgagc catcccagga aataatagca
     3481 gacgcctgag gtcgacggga gcactgagca aaaatcaact cctgcaagaa gcgattgtcg
     3541 gctgggggca tggaactgtt ccattgttgt acttgctcga tgtcccgtgg cccgataaag
     3601 ctaatatctc caatccgtcc tgttgcaagc gtatagatgt gtcgcaagac atgctcgaac
     3661 tgatgagcca ttcgctccac ctcatcgtgg cctattactt gcgcgtcata tgtaatatcg
     3721 aacgaaatcg cgctcttgtt agcgctagta cgaaagacga gcatcatcgc gtatgacgag
     3781 aacgcggtgt agtccatccc agtctgtgtc gttcccccga taatggaaaa gtttccagct
     3841 tcgttcttct cacaatccac gtcactatct gtgggagctt caatgataag caaattctgg
     3901 aagcggcaag cttcggaggc atctctacta caccggctga tgcgctgcag gccagcctgt
     3961 tcgtagggaa tcatgcgtgc gagagcgtcc tgaacatggt ccagcgccat ctccacggta
     4021 tcttcctcgt tgactcgaat gcgcgtcggg acggttgcaa ttgttggacc cacgatattc
     4081 tcaatccccg gtacgtcagc actacgcccg ttgactgtca ccccgtatac ggtctcgtcc
     4141 gcgtctgtat agtgggcaac gagtaacgac caggcaaggt gaatataggt agcggcggta
     4201 tgctcctcct ttccggttga ggccaagttt ctcaccacat ggcgatgcga tgcgtttacg
     4261 cgcggccgat agttgccaga cggcaaggtc gggaatatcg gtgcattcac gccggcgagc
     4321 tcggaggccc agaactcgtc tgcccctggt agctcttgcg tgtattgaat gaaagagcgg
     4381 tatgaggtgc tcggtaacag atcccgccca atgtaggcac gctgtagttg ctcatgaacc
     4441 aagcggagcg accagccatc ccagattgag tggtggattg tcatcatcag ctgccgatgt
     4501 cgagggcgat agcgaaaccg aaccaaaggc acaccgatct tggtgatctc gagtgcttcc
     4561 ccgtcgctag agaggagcat ctcgtcggtt tcttcctccc acacgaagtc atcgacgatc
     4621 accgcttgca tgagtccctc gtgggtttca atgatacgtg ttcgcaaagc agcattctcg
     4681 gacaccaccg acagccacgc ggccttcaaa cggggtaact ccattctgtc gggaatatca
     4741 aatattatct gcccggtata catgcctggg tgttttaaag acgttatgaa catgccctcc
     4801 tgcagtgcag tacaagggta gatatcttca atgagattcg aaggcacacg gcactgcttc
     4861 tgcgccaggt cgacaatagc atgcctcgtc ggcccatgca agagggcaaa cggaggtgaa
     4921 gattcccatg tacggtctat tgtttggatc aaacctgcac gttttgattg ctcagccagc
     4981 gtactctgcg acgaaaggat atccttggcg tgtagtataa gcccggccgc cctggccgct
     5041 gcaacgaggc gaatggcttg gagtgaatcc cccccgaggc gcaggaaagt gtcgtccatg
     5101 cctatcaagt cgatgggtag gttcagcaca ttgctataca gacttcggat ggttgcttct
     5161 ttgggtgtgg atggaggacg tttaccaccc gcgggcgaga gtagaaaaca ttgaacgtcc
     5221 cgtctcgaga gggcagcagc tcgggttctc aaggctttgc ggtctgtttt cccggatgca
     5281 gtttgaggga gagttgatat aggaatgaat atatctggaa ccatgtagct gggtagatgt
     5341 gtttgtagat gcttcttgct gatggcgaat tgctccatga tctgcgattg cggcgccagg
     5401 aagagacgat ctcccgtgtt gcctatgacg gaatcagtgt tagatggacg gactaagaca
     5461 aaggcaatga gcttttccga tccatcgtcg gaaaaggtga ccttttcgac aatgacctcg
     5521 gcattgtcgt tcgggagggt cagttggaga tggtgttcga tatcagggag ctcgacccgc
     5581 tggccccgaa tcttcacttg agcatctttg cggccgtgta gcagcagcgc accggttatg
     5641 ctgtccaggg aggccaaatc cccggtgcgg tagactcggt gctgataaga ggtgcccttg
     5701 cggtgccggc gcagccatgc gggtgtatca ataaatgcct ggcgagtggc tttgggatcg
     5761 ttgagatagc cgcgaccaac aatgggccct tccacgagga gttccccgac tgtaccggtt
     5821 ggcatcagct cctctgggtt ctccggacta ataatccagg ctgtcgctcc tgtggtgtac
     5881 ccgatgttcc gaggatcaac cgcagcctcc accctagact gtacagacac gttgacggaa
     5941 cattcggctg gcccgtatgc gttcatgcag cgaattccca tttctttgta tgctcttgca
     6001 tcggaggggc gcatcaactc gcctcccacg atcagggtgg gtggcgggtt gcaacattct
     6061 gtccatggca ccgtcctcgc aaaggatggg gtcataaagc agtgggagat ccgtaggttc
     6121 ttataagaca caacgaagag gtttgggtcg cttcgttccg actcgctcat tacgcataaa
     6181 cagccgcccg ccattagagt actgagcgtc tccatgatgc tgacatcgaa ggcatacgag
     6241 gcaaattgaa gaacgcgcga cgtcgaatcg atgccaaata ccttcaggtg tgaacgagct
     6301 cccgagcaat atgatcgatg ctcaatgaca atgcctttag gctttcctgt cgaacccgac
     6361 gtgaacgcga tataagcggc gttttcaggt cgagatcgtg tgtggccagc ttggccggga
     6421 ctcggcaagc atgcccggct tagatgctcc acgaccagga cagaaaacat ctccaaacac
     6481 tgtttactga gtttctcact cgtaaggata aaccttgcct ggatttcctt agatatctcc
     6541 tccaccctgc tccgtggatg ggatggatcc agaagcgtga atgctcctcc gctcttgaga
     6601 acgcccaata ttgcaaccgt tgtccatcgg gacttctgca tgtatatggg tataatgctc
     6661 tctggtccga ctccagagag gatcaagact gacgcaatgg catccgacag gctgtcgagc
     6721 tcggcatagg tgaatgatcc gtcccatgca ttgactgcgg gtgagtttgg agctcgctgg
     6781 caatgctcac gaaagacggt atgtacgcaa gtgtcccaaa atgcggattc accctgtcca
     6841 ttcttgccgt ctgtcgttgc tttcatgctg tccaccgtcg gaccgtcctt gagcgtattg
     6901 tatggaagat tacctctctg ttcggagggt gcgcctaccg caagagccat cgccatagta
     6961 cagacgggaa aaaaatatcg tacggagtgc ttcaagaaag ggcttattat caattggcag
     7021 gggctttttc agaggatctt gttagaatat tggacaagtc ttctttcgga gaaagcaatc
     7081 tacacataga tatacgctac accctgtgaa gccgtagacg tggatctccg aaaacgaaaa
     7141 gctacgctga gtgacagaaa aatgcgggta ctggcccact acactccctg gacgttagat
     7201 tctacatgtc tgagtatagt ttagcttgcg tgataatgaa agttactgaa gttcccgtcg
     7261 ttgtttggca ggtagaacat gtgtggcaga atccctatcc catagtattc ggcaaggtgt
     7321 gtgaattgag gcaagccaaa acattgtagc attccatgca tgctttaggg atctgccttg
     7381 atgagcaaag actctgcact gtacctttgt cgatcacaaa aggcgggcaa aagatcagca
     7441 agacgtccag caagccattt ctacgccacc tgacggacag ccccagatag aattacatac
     7501 tccaatactg ggcatattac tgcagcacga agaataggga gcttctttcc tgttcgatca
     7561 cggagtgctc tcagcccatc gaccgtcagc tccgagcttg agcgtcacgt aactatgaag
     7621 acgatagtcg actggcctac aacaacgcca gtgcatggcg tacaatcaat aattcaatat
     7681 taccgcggca aatctccaag ggatctgcat tgcagcgaga atggaaggac ataggtacgt
     7741 ggcgtctgcg gctatcttcc ttgtgcgaga acgtagtcag ctgggttttc cctgctgaaa
     7801 gtagacctgt cgtatggagt acagcatcaa atgtcatgaa cagccatgcg aagaaaaatt
     7861 actcaattga gacttgtcaa tcgtaaaccc cacccactgg gcgagagtgg agaaccaatc
     7921 taaacgccac cacccaggat gatggcatga tttccgtgaa tagacaatgc atgaaacatg
     7981 atcctcgatg caaggttcgc agctgcacac cggtgatgtc cgaagatctt gccctgtcaa
     8041 tcacatgaac caaatgcctg actttgaccc accggcaggg acaccgtgtc aatcgccctg
     8101 ctgccctggc accggtccag tagcggcacc tgcagactgc agaggaacga ggaatcggat
     8161 tggacacgtg tagcaaacga attaaacgac tggtgagtgt tccaggcttt ggtcattgtc
     8221 cgcccagttg gtgaacgaat cagactgtgg tgatctcatt caggatgaaa ggaattgaga
     8281 atacgaactg ttgaagacaa tgcagatcct aggttacgag attgccggtc tagacgttgt
     8341 tcagaactcc tgacgaccga gtcatgggcc tacagcgtgg acaacaggat tttgccattt
     8401 gtagaattca tcaggcttga ggacctgggg accggacact gaagaaagtc ctattttacg
     8461 cggccaacga ggtacctgcg gaattggaga attacagagc taatggcgtc tggtcaaaac
     8521 gaccggcatc tgatgtatac ccatggcaaa gtgctcatcc gcagcgtcca tccaccggat
     8581 cccatcctcg ccctctggaa accgtacgtc gaagctcatg atcagacgag ccaccgttgt
     8641 gcggatattc atcaaggcga gtggctttcc aatacatgaa taaggaccta gcaatttgaa
     8701 agagagagtg agtgacgatt ataatgacct cgcaagatct gagcggatgt acgaaccgat
     8761 ggagaacggg gcaaaggccg acgggtcttt taccaagtcc atgtgcttgt accaccgttc
     8821 tgggttgaag atctcaggat caatgtacgc cgcttcggct aaggtgggag aagtgcggag
     8881 tcagacgtca aatgtcacaa gttcagcgag tgtagaaagg ttctcgtaca tcgacccata
     8941 ctccattgcg gactgaacac cgtcatattg cccggaatga agacatcctt cacatggatc
     9001 ccctctggtg gggtctttcg cggaatgaca ccggggatgg gagggtgcaa ccgtagggtc
     9061 tcgttgataa agccattgag atgtggtagt ttggcgaggg tgtcgtgctg gtactcgccg
     9121 tcactatctg cttcgatagg atccagctcc gctcgtagtt tgtcgacctc atcaagatgg
     9181 cgggctaatt cgtacacgat actcgtcagg ctcgttgctg tggtatcact attgacgtgg
     9241 cgatccattg gtggtcagtc cacttggatc ccaatgtgtc tggcctgggc agcaactcac
     9301 cttcctgctg tgatgatgag catggcatct cccatcagca tgttgcgttc gtcctcggta
     9361 ggctcccggc catttagcgg cgccagcaag gacgcgaaga tatccggaac atccacttgc
     9421 tcctacagaa ccaatgttca gcggaagaaa cggcaggcag atgggtcagg aagagggcga
     9481 cccacaccca cgcgacgcag catggtgtct gtcgcaaacc cgatgaactt atgccagtcg
     9541 ctcgacaacg agggcatggt agcgagtagt cggaagaacc agctgggaaa caaataccga
     9601 tacccgatca tcccatgcat gagcatgtct accgcccaat gattccggct tgcgtccagc
     9661 atgtcaaagc tgcgcgcaaa ggccaggtcg cccatggtat catagctgta aaaattgaac
     9721 cactggctga tattgattgc cgattccgca acagccctcg cttccaagcg ctggaagagc
     9781 ttctgacgat agacccgcat gcgctgctcg taaccacgca gagcccgatc cccgaacccc
     9841 gcgctccaga cccggcggcg ctggtcgtgg gctattcggt cccggtagga atgtagcgac
     9901 atcatcggat ggccgttgtc gtagaaggtg ttctttgaac agcgggagtt gggtccgtag
     9961 atcatccgga cggcttcggg gtggatgata gacacttcag agggtccaac cctcacgacg
    10021 gggccgtatt cctcgtgcag ttcatgaagg atccggaatg atggcccacg cctcagacgg
    10081 aaggataacc agaatgaaga tatcttggct gcccaggggc cacgtatctg gcggaggggg
    10141 tggaacaatg ttcggtagag gaggagcgac gcgaacagtc caacgagata tgttgccata
    10201 agcagagaga cgtctttgac gaggtccatt gaacaaagag tatactgggg tggctttttg
    10261 gcatatagta gggctgccac gcccatggtc aggcagagat gaaatcgtac ataccgccag
    10321 ggatacagat ggtgttcccc atatcggaaa tacgagagat gggtgcaaat gccaattagg
    10381 ccagccgtcg ccagataccc gcacttcatg accgatggca tcatgagggg agtatcagag
    10441 tgactcggtt tcatactgct ggaaggggct cacttgagaa ccgctcatcg ttaaaaagac
    10501 ggaacacgcc gaacatctga atcacgatca tacgcataga ccctaaagtc agagccaaga
    10561 gacaaggatc gtcgatcaaa tggctcgcaa tgaattggtt gcacacaaca ccatgccaag
    10621 gacccaattc ttggccgacg cagtgtaacc ctgcgctaat gcaggttcct gctcgaggcc
    10681 agactagcaa acaaaagcgg atgtgtctca tcccatgccg gttgtgacga ctgtgccacc
    10741 tgggctgcga gatggccctg agatcagcgg tgtgactatg tgcgcggctg cccagttccg
    10801 gagacgtatc tccggattga agctatatgt ttatctatca tcgacaacca aagctggctc
    10861 gactacctac caatcctgct gagtagtact ctgcattgct gcaccacacc ccgctctctg
    10921 tgttctgtac aatgtccgat cttcccgagg ttgctaccag gctgagcaaa aatgttgaga
    10981 ttttagtgga tgagattgac aagacggggt cccagccagg ttgcgggaag ccgactgccc
    11041 ttggcgctaa agggctcgca gcccgagacg agatcatcct cgccgctgaa aagctcctcc
    11101 aacaaggtcg gggcccgggc ccgtcgttgc tgagtctgct cgaatcggta gctcccccct
    11161 ttccctgcct gtttctccct gtgacgtgac tgacgattcc catgaatgac acaggcagtc
    11221 gacatcggca cgatccagac tttgatccgg cttgaagtcc cagatcaggt cccgttgacc
    11281 ggatctattc catacgatgc actggtcaag aagctgaaga ctcctgtgga tccggaattg
    11341 cttcagcgtc tgattcgctt cacccgatta gttggattcc tcgatgaaga tgcagagggt
    11401 gccgtgaagc acagccccat gtccgccatc ttcgtgaatg acccggacac tgccggtcag
    11461 gctcgcttca tggcagactt tggcattcgg ccctgctcgt tcatatacga gtccatcaaa
    11521 ttggacccca gcggcgaagc ggcgcgccag ggtccattgg ccctgatggc cagggagccc
    11581 ggggctcgcg agggtccgac gttcttcgag gtcttggaga aagacccggt aaatcgaaaa
    11641 cgatggcacg atgggatggc ggttcataat gactcgatgg tacgccacgt agcgggcgcc
    11701 tatgactggg gcacggttca atcgttggtc gatgtaagtt actaaggccg ctattctcgt
    11761 caagggagtt gctgtacacc aacaaccgtt ctactctttt tactcacatg tctttcagat
    11821 cggaggatca gaagggcacg tcgccgcagt cattgtcaat gcctttcctc acatccaaat
    11881 caccgtccaa gaccggcccg aaatcatcga gaaggctcgt caacggggag atcgacaccc
    11941 aaacattatc ttcgaggagc atgatttttt tacgccccag ccgcgcatcg cagatgctta
    12001 cttccttcgt ctcattctcc acgactggaa cgatgcggat tgcactcgaa tcgtccggca
    12061 gatctcctcc gctctacggc ccggtgcgcg actgctcatt atggatgccg tcttgccgga
    12121 gcctggtgaa gggtctctgc agagtgagcg acggttgcga cggagtgata ttgggatgta
    12181 cacgctcttc tccgccaagg agagaagtct ggctcaaatg cgccggctgg tggaagattg
    12241 tgacagtcgg ctacggtttg agaaattgta tactccgcct gggagccatg ctagtatgct
    12301 cagttggatc tgcgagtaac tacaatactg cattagtttt agtagagtta ggatcgtcta
    12361 ttagagcaga actaggaatt caaggccccc ctgcacttct cggaaaccaa cacacctctt
    12421 ctaacgagat gtgaaataat gaccttccag caagacagtg tacactccaa cccccgaatt
    12481 gacagcatga tgagctacag gactcatagc cccattggat cggcgtctct atcactcccc
    12541 agccaagtcg agtgccaacg gttgcgtcaa tcagctgaca tatgttgcgc cttgatagag
    12601 gtaccctttg ctgtcccttc agcgtattcc agatcagggg gcctaccaag gtctcagctc
    12661 agccactttg ggagagcgta gcgcttactg ctggtggtgg tggtggagct gcagatgcat
    12721 gtttgtaact agtatgcttt gcttgaaaat gagactgtat gcatttttgt gacgagtatg
    12781 cattagtgtg catatgcatg aaaatcagat tatatgcatg tttgcagcta gtctgtcgag
    12841 gcgtgcattg ttcaaaaatg agacgaccat agagaggatg tgggtgtctt acatgcgcct
    12901 cgggatcgcc gtctctggcg tctgctcgca tgccctcgga ggttggataa aattccatct
    12961 catctgaagt atcccaccga aaggcaggat tcccactaca atttgcagtc actattcctg
    13021 attcctcagc acgcaaggat gccgccagca ccaccggacc agaagccctg ccaccagctg
    13081 cagcccgccc cttaccgggc cctcagtgaa agcattctct ttggaagtgt tgacgaggaa
    13141 cgctggtggc atagcacagc gcccatcctc tcaaggcttc tcatatcctc caactacgac
    13201 gttgacgtac aatacaagta cctgtcgctg tatcgacacc tggtcctccc cgccttggga
    13261 ccctatcccc agcgggaccc ggaaacgggg atcattgcga cgcaatggcg cagtggaatg
    13321 gttcttaccg ggttgcccat cgagttcagc aacaacgtcg ctcgggcgtt gattcgaatt
    13381 ggggttgatc ccgtcacggc tgactctggc accgcacaag acccattcaa caccacgcgt
    13441 ccgaaggtct atctagagac cgccgcccgg ctcctgccgg gggttgactt gacacgcttc
    13501 tacgagtttg agaccgagct ggtgatcacc aaggcagagg aagccgtcct ccaagccaac
    13561 ccggacctgt tcaggagccc ctggaaatcg cagatcctca ccgccatgga cctgcagaaa
    13621 tccgggaccg tcctggtcaa ggcgtatttc tacccgcagc ccaaatctgc agtgactggc
    13681 cgctcgacgg aggatcttct ggtcaatgcc atccgcaagg tagatcgcga ggggcgcttc
    13741 gagacgcagc tggccaatct gcaacggtac atcgagcggc gtcgccgggg cctccatgtc
    13801 ccaggggtca cggcggacaa gccaccggcc accgcagcag acaaggcgtt cgacgcgtgt
    13861 tcgttcttcc ctcatttcct gtccaccgac ctcgtcgaac ccggcaaatc gcgggtgaag
    13921 ttctacgcca gcgagcggca tgtgaatctg cagatggtgg aggatatctg gacctttggg
    13981 ggccttcgaa gagatccgga tgcactcagg ggtctggaac tgctccggca cttctgggct
    14041 gatatccaga tgcgcgaggg ttactacacc atgccgcggg gcttctgcga gcttgggaag
    14101 tcgtcggccg ggttcgaggc gcctatgatg ttccacttcc acctggacgg gagtcagtcg
    14161 ccgtttccgg atccccagat gtatgtctgt gtgtttggga tgaactcgcg gaagcttgtt
    14221 gaggggctaa ctaccttcta ccggagggtt ggctgggagg agatggccag tcactaccag
    14281 gggaattttc tagcgaacta gtgagtttca gttcctcccc gggatttact gcttcgaggg
    14341 ggagtctcat taatgcaata ctctgatagc cccgatgagg actttgagaa ggccgcgcac
    14401 ctttgcgcct atgtctcctt tgcctacaag aacggcggtg cctacgtgac gctctacaac
    14461 cacagtttca accctgtcgg ggatgtgtcg ttccccaatt gaagcatcta cgctttttcc
    14521 gatctctctg tgtcattctc gatagatagc aatgatcata cacaagactt agtaaatcaa
    14581 gaggagttca ccgtccattg gacctgacca cttcgtactc tatcatgtat ctctcaaaac
    14641 tccacatcca tacatgtacc ctgcggcgca taaaccatta gtctacggag tcgcagaaat
    14701 cgacaagaca tccggtaaca cagccatgct attctcaatg acctcctgat acttctccga
    14761 cctcggcgtg aatctcactt caaagtccgg taggaacgcg gccagtgtcg tcccactatc
    14821 caagaaccgc tcctggtcaa tcgggtccgc accatccggc agggccatgt cgaacgccca
    14881 aaacaaacga gcagtggcca ggaacaacga atcctggccc atgtggcgcc ccggacacgc
    14941 gcgctggccc attccataca tcaactgcgg caagtctggg ttctcgatcc atctctctgg
    15001 ctggaacgcg aaggggtcga gaaatattgc ctcgtcgtgg tttatggccc acacgttgac
    15061 gaggacagta gcgccacaag ggatatggta gcctctgcat tcgtcttcgt cggatgtggc
    15121 acggggtgac cccatgggtg ttagggagcg ccaacgcatg gcttctttga tgaaggcttg
    15181 cgtatagggc aattgggccg catcgtggaa gtccggaagg cggcccgtcc cgaccaccgc
    15241 gtctagctcg tcgtgcatgc gccgcgtggc atccgggtgt aagagaccag cgaggatgat
    15301 aactcggagt gcctgtgacg cagccatgga ggcctcatac agcgacccga ccatataggc
    15361 gagacgcttc aactcgactt tacttccctg ctccccgtcg ccatccccac tcccaattcc
    15421 gtccttcatg gagaattcct tgacccagtt ccagcccggt cggaccagcg cagccctcgt
    15481 ccgtgctacc aggtcagccg tcagccgatt gtgcagcata tcagcgtcct tcttccaccg
    15541 gaccggcagc cgatcgacca gtgctttggg aagaaccaac tgggtgagaa taccagcagc
    15601 accagagaat agcgcctccg catgcagtgc gatagcgcga ttgagctcct cgagccggtc
    15661 aatcgcctcc aacccggcat gatcgacaca tcgctcccca tacgccacag tcagaaagac
    15721 actggcaata catcgacgca gacaaacggg gaagtcgttt gtggacagaa gctcgtgcag
    15781 gagctgcgtc gtttccacat gctggacgtc gcggtacttg accgtcatgg agggtttgag
    15841 gacggagctg cggatggccc gctggagttt ccattccgga ccgtagggaa gaatcgacgc
    15901 attcaggcca cctgtcgcgt ggaggaagaa gggcacggag ggtcggctgc tgtagattgt
    15961 gtttcggcgt tcaatatggt ttttgatgag gtcccaggag gagaagacga cggcgatggt
    16021 gtcggcgagt tggacggaca tgatggggcc gtaagtgtcg gaccactctt tgtacttctt
    16081 ccatgggatc tggcggggta cctggtggag gttgccaatc ttagggagtc gtggaggccc
    16141 cggggggaga gaaaggtgct tcccatgggg cctggcgggt gctgtgtatc gaatccaaag
    16201 gtatagaatg gggaggacga tgatgaggaa gagcacagcg ggggacagcg ggagtcgctc
    16261 catagtcagt tgccagattt gccctgcaga tggtcaacgt cgacagagaa cgatcctttc
    16321 ttcctctatt gaacacagag tacggacgtc ccttctgtgc tatttcgcag aatgtctggc
    16381 gagatcttct ggctgtcact gcggcgtcac atgccatgtc caaagtccct cggccagatt
    16441 cagcgccacc tttctgtctc aatattgggc ttcaacagga acgatgtgca gcaaatgcag
    16501 tggaaccatg gcagctgtga tcttacactc gccctgcagg agtcagctgc agatagtccc
    16561 cacagcccta aagaaaacaa agacaaatag ataaagaaaa tagatatata aaaattgaaa
    16621 taaaaaagta aaaaacagca agaacagggg ttcgacagtc catgcatgaa ctagcttcaa
    16681 tagcgggcag agctgaaacc agctgggcgt tggacatact tagttttgga tgcagagatt
    16741 ttggtgacag cccgcttacc ctggccgtag gacagagggt tctagctcgc ctggttcatt
    16801 agaagctctg attctgatta cgagctactc catagtcacc aagactatgt gtgcacgcct
    16861 tcaatgaata gagtagtggc ttaggcggta ggcagagggt tggtattggg tggtacgact
    16921 tttgttttat tttgtcttca aggaaaggtt tgtattggtg atagacacac aggtttgcat
    16981 agagccattc tgtctggtag tttcaggtgc ctacagtcca ttgagcagta aattacacag
    17041 taagatggac atcagcatcg ggccagcatc tcagctcagt gtacgtagaa ccagatcaca
    17101 gtagttcact aacgaggtat ctgcagccat gacactctct aagccggcga atcagcagcc
    17161 ttcaactgca gcacattctc cagccgctta tcatctatca ggttgatgcc cacaatgttg
    17221 ggatcggacg gtttcatggt tctccagccg agcatcctct ggccgagaac agtcatcgac
    17281 tcgaccatct cgcgcggcat cgtccggtag gtctcgaatg gggtcagctg gacgctattg
    17341 aagtacgcga ggacaacccg tcgaggtttg ccggccgtcg tgcgattccc accgcccgca
    17401 tgcaccacac gctgtcgtac aatgagcaca tcgcccgggt ccatagtcgc gagaactgcc
    17461 tggtcgcgct ccggcgtccc gacctctgtc caccgatgac tgccgaggat gacctctgtg
    17521 gcaccattct cctccgtgaa ctctgtcagg ggaaagatga cgctgaggga aatcggcggt
    17581 gcttccaagg gctggtagtg catcagcggg tgggtggcat cgtcgcggtg gaacggctgg
    17641 gcgggcattc ccgattcaat ttcgcggagg aaggccgcgc tgagccagta atcacccgtg
    17701 cgctggaagt aggcctcgca gatggcgtgg atgaccgggt tgatgagaat ggtgttgcgg
    17761 aacgtcgggc aagtggtggc gacgttcggg acatatttga agtgaggggg gtatttgtcc
    17821 gccagcagcc gttctccttt gggaggtggg atggccattt gcacgtccaa ctcgcggttg
    17881 aagctctcga cgacgtcgaa gggcagcagg cccttgagga taaaggcacc gtcctcttcg
    17941 aggagcctgc acatccggtc aacgtcggca tcggcggcga ggcgctggag ttgtggcttg
    18001 gagtcgacgg tcatcgtggg aaggaatgat caattcttct tcaaagtagt ccgagtagtc
    18061 caagtaaacg cagagataag agaatggtcc tgggtggacg gcagctgggg ttgattgtct
    18121 catttaacct tgagggcgag gttctgtgtg ggatgcccac gtttgggcta cacgtttggt
    18181 tggaggtgtc ctgggatctt gcagtttgct tcgaatggca cactcaccgc acgcataaag
    18241 gaagaagtca tgggcgcgtc agaggttccc atgcttggaa gcaaacagtg tgatgggtgc
    18301 ccactttctg cattcgccgc tcactcctgt acgtcctcgc cagatgtcca ccagttctgg
    18361 ccacacaacc gtacagtcac aaaagccaaa ctaaaacgta atgaggcagg cttctcagct
    18421 gcatgcagtt gacacactat ggaagtctct ttcggccttt ggtttgcgaa agctgagatc
    18481 tgtaccgccc atatttcctc actcctaact cggctgagga tggcagaagg gccaattccc
    18541 caggtagcca cattaactgc atgtctcagt gctgttcctt gatttctcaa ctgcgggccg
    18601 catgctgatg caaccgatgt cacatctcca aggcggttaa ctcctctctt gtcgactggt
    18661 tgagctgaac attgaacgac tatcatcgag acagtcggct gaatgtaggt gaggggttag
    18721 catgggtcga gactgaagaa gactgcaagt gctagatagt ctgctaggga tgctgctagc
    18781 tcggctacac gtcacattcc tacgcttcgg tgaactgttg catacgatgt ccctgcgaac
    18841 aatgaccggc aatgtccggc ggcatagaga ttcaattacc aaggaggaac acgcaactca
    18901 cgaaagcttc attcaggtaa aagggctctc cgtatctctg tactgcatat tacacaagaa
    18961 tggacagatc gaaaaagctc ctacatgccg gatgaagccg agacgtattt ccatctgcgt
    19021 tttctatcga ggtataatcg gcgagtggtc aatcgtagga tgtagacagg acacaacaga
    19081 atacgccttc actacccatg atgatcgcct acccatgcgg tgcagtttca gtcccccgcc
    19141 gtcttctcac cgacatcatt gccccaggat ccagctgcac aaacatccca cgcgcacgca
    19201 attccggagg ggatccctcc acagccctaa tgtcgtaatt gaggagaata tgacacagaa
    19261 tgagtttcgc ttcatcgcag gccaggaagc ggcccgggca ggcatgcttg ccgtggccaa
    19321 aagcgagatg gctcatcctg gtcttggtga acggcgcaag gtcaatcttc gcaggatcct
    19381 ctctcatccg ctggaaccgg tagccatcga aagtttccgg ctccaggtac atttccggat
    19441 cgaagcggag atcattcgca aaggcgatat tggtaccctt gggaacgaca gtgccgtcct
    19501 tcaacgtcac tttttctttg gcgaggcgga acatgccgac tgagatcgga cgtcaagtca
    19561 gcacgagacc catacggagg aagataacta tattcggagg caacgtactg atcacagcgg
    19621 gttcaagccg ctgggtttcc ttcatcacac tctccatcaa cgtgagtttg cgtaatgagt
    19681 ggcggtgcaa gccacgattc ccaactaccg aaaccacctc ctcgcgcaag ggctcaatga
    19741 gctcggggtg cttgcaaagt cgtgctatca ctttttcgac caaatcactc gtagtctgaa
    19801 aagcaacggc aataattcgc agctgcgcca tggtagcatc atagcgggct cccttggcat
    19861 actgatcgat gaacaccaag ttcgagaatt cccgcttcgt tggctgatcg ctgcaatacg
    19921 cgcgccgttc acgctcgagg gccggaagga tgatattacg ggcgcactgg atttgacggc
    19981 gaagagcccg gcacgggggc aggaaccaat ggatcacagg ttgaagaaag ctgggccagg
    20041 actggacggc ggcgacagca atagctcgat ttgtggtgaa ggatttcgca atgtccagcc
    20101 attcggggtt gcggcagagc tcagggccca gcagtgctct tgttgtcatt tgggcaatca
    20161 aggccagtac ggtttccggg atagagacgc catgccactc tgtctgtgat cagacggtcg
    20221 tccaactggc ctaccgggaa cgcacgtacc tgtcgagtcc gtccacctgg tttgcaggca
    20281 gttcatagct tcctcggaaa gggaaggtgt caagtgtact acattccggg ctcagtaata
    20341 attccccgag gagaagaggc tggaaactaa ccaagctcct tgtttaacgc acgaaccgcc
    20401 atggggggca cttgattatg cagcgaacct tggaacatgc tctctaagcc aggcaggtcc
    20461 acaagtaata cctagacgga tgagaaccag atcgttctgc gagaaatctg cgcaatgaag
    20521 agggcgacat acgggatcaa ctgcttcatg agcgccaaac cgactatcat tcttgatttc
    20581 ctccgcatac tggtctttca agatcaaata ggtgaccatg ttggtcacca gccggaacgc
    20641 cgagtggccc tacaggacgc atgttaaccc ctgttggcga agatacggaa gctacaccgg
    20701 atctctgcgc ttactgtttg gaggccctcg ttaagtagag cagctgcatt atattcaaac
    20761 tgctgcttgg cctttgtctg aaacaagtcc cgtgggtgtt ggttgatggt tataaagggg
    20821 tcgctgccca agggaaacaa caatatgatt cccaggatga cgatcaagct tgcgccgacg
    20881 accccgaggt agggcagctg aatcgcatcg agggtttcca ttgtcacgaa tcgcttttgt
    20941 gggatgcacc gagtgcgtgc caatggattt ataaccgctc aggtacggct aggaattggt
    21001 caggcggagg ccagtggtcc aggacgaaga tggggagagg gagaatgttt tctgacctgg
    21061 cattcgcctt tgctttttca tgacaaggat agatataggg aagcccccac aaggcaggtc
    21121 tgtgcggatc ttgtccagtt tttcagtaat cgctagtggt tattatgatt ttgcctaagg
    21181 tggcgtatga tcccagacgc attgacagga tccgatttgc caagtcaaag tcgtagcaaa
    21241 agcatcaatc aagagtctca taggaccaga cgtcattcaa tttcttctct ttcaagaaag
    21301 gatttgcaga cgcaagccgc agctaccatg catgcatggg atagtggacc acaaacacgt
    21361 cttgcacagt agcagccctg caacatggct ggctgatgct accaagatcc cagctgcgca
    21421 atgcactgtt gccaccggct aagcgtcaat gatgtgtgct ccggtatagg attcaaaggc
    21481 gcatgactgt acatatccgc aggccgaatt gggatgatac ttaaaacatt gaatgcccgc
    21541 ctcgtcctgc agccagcagc gagagttgtg actccctaga ccgtccaggt tttctccaat
    21601 tttcgattct ctatctcact cgagcatcat ccgcatcccc gtcccacaat gaccatacca
    21661 actgagattt cgtgccctga agaagacgca ttccagctcc tcgacaagtt ctcatggttt
    21721 cccagcgacg accagcgacg ttggtgggaa tatactggac cctatctgct caagcttctg
    21781 cgtgatgcta aatatccgca gaaggatcag gttccctgcc tctatctcct gcagcaactg
    21841 ctggttccat acctcggcac cttcccagtc gtgggacaag cacctctgcc ttggtggagc
    21901 aatgtgacca cctatggcgt tccgttcgag ctcagctgga atcttctgca taatatcgtg
    21961 cggattggct tcgaaccact ctcacacttg gcagaatccg gcgtcgatgc tttcaacaag
    22021 acagcgccag aggaatgcgt ctcccgccta gcgtgtcttg acaacaccat cgatctagcg
    22081 cggttcagac acttccaaca ccaccttttg gtgactcccg aggaggaaac atggttgctc
    22141 agagagaaag cccccctccc caagtctgga cgaggccagc aaaccctggc cgtggaattc
    22201 cagaatggtg gcatcagcgc caaagcctac ttcttccccg gcatgaagtc gctggcgact
    22261 ggactctcgc caggaaagct cattcttgac tccatcgaga ggctcgctct cccaggattg
    22321 aaggaacccg tgcatcacct ccgcagcacc ctcggcctgc aagacgacgg gcacccgaca
    22381 gataccgcga ttgccccgtt ccttctcggt gtcgacctgt gcactcccga acgaagtcgc
    22441 ctgaaattct atgtgaccga ccaggtggtt tcatgggatc gggtagcgga catgtggact
    22501 cttcgcggga aacgtctgga agatcctcaa tgtgccgatg gtctggccct cctgaggaaa
    22561 ctgtgggatc tcctcgcgat ccctgaaggg tatcggagca acatccggcc ggactttgct
    22621 tttgggacgc ctcctcccga ggactaccgt cccgttatga tggcgaactg gaccctatct
    22681 cccaagaaaa aatttccgga cccccagata tacctcctga ccgttgggat gaatgacgcc
    22741 gtcgtcatgg acgcactcgt ggcgttctac gaggttctgg gttggacgga tctggccagc
    22801 acgtacaagg acaaagtggc ctcatacttg taagtgatcc tgtttggtgg gtgcatgcag
    22861 caacgggctg gaatggaatt aacctcgttg acagccccgg ccctgacttt acgaaaacca
    22921 attacattca ctcgggggtt tccttctcgt atcgccactc caagccctac ctgagtgttt
    22981 attattcgcc tttttgagag agtgcagaaa gtgctggggg gagcacgact agaggatcaa
    23041 gaggcgaaac ggcaatctga tgctagaagg cagttgtctt tatttgcgtt aggatgacga
    23101 gtctcaaatc atatcataag ccatcccgct gataattgtt cttcgaacct ctccttagtc
    23161 ttgttgagat cactatatta ctgaatacct cttgtatcgg tttagtatct tgctgcgcga
    23221 cctggttggc agtcctcagc ccttgaccat gtagttctgg cacttctggt ggtcattcac
    23281 caggcctcaa cttgatggaa agcacgatta ttctcatgga ggcgcgtcac caatggttgg
    23341 tctatcggtt gctgctaatg cctctcgtag catctgctca attgtttcta gagccccaac
    23401 ttctgccaaa tcaagcggcg tgcatgcgtc gaaggaggca ataccaggat caacaccagc
    23461 atccaataga gactggacgg tgttttcatg ttcgttatta accgcccaat gcagagccgt
    23521 ccagccatca caatcctgga gatctctgat ttcactgttt ctcaagagaa ctttggcaat
    23581 ctcatcctcg ccctcctggg cagcaagatg caaagctgtt ttcccgctgt tatcccgggc
    23641 agaggtatca gcctctgtat cgagaagaag ttcgaccact tcaatttggc ccccgagaac
    23701 ggccctgtgc aacgctgtag atccgcttgt atctttgaaa gatagatcaa tgccatgtgt
    23761 gatgagaagt tgaaccatca attcgtgccc agcttctgca gcctctaaaa aggcctcctt
    23821 gacagactcg tcaagggcgg taccaaattc aagaagcagt tttgcgatca ccacatggcc
    23881 ttggagtgct gcatagtaca gcggagtccg accattgata tctttgacgt ccgatctggc
    23941 ttggacactc agcaatattc ttaccacatc ctcatgtcct acgtcagctg cataatgcag
    24001 gactgtgcga agtttgttgt cggtgagatg tggcttgctg ccccgttgga taagcaattg
    24061 gacgacggct tgatgtcctt tctgaacagc caagtgcagc gctgattccc catgttcatt
    24121 ttgaatctgg tcgagagccc ccgcgtccaa taaagcagtc gttataccaa catggccctc
    24181 gttcgctgcc caatgtagcg gagtccaccc tgtatggcta cgagcatggg tatcagcttt
    24241 gtgcttcagc aaagtaggga ccatctcttc atggcctttt gcagcccagt gtaagggggt
    24301 ctgattcttg tcatttgcgc tatcgacatg cgctccagcc tctatcagca tttcagcgat
    24361 tgtagctttc tctgaaagga cagcaaagtg gagtggtgtg ttcccatctt catccggaat
    24421 tgaaggacta ctccccgcac ctaaaagcag ccgcacggtg gcaacctggc cggcgccgct
    24481 ggcttggaga agaggggttt gtccatctga ccgttgagca gacacatttg ccccagattc
    24541 tagaagaagc tggaccacgt caacgaaacc cattaaagat gcctggtgca atggcgtagc
    24601 atttttgcga ccttgcagag aagggtctgc tcccttattc agaagctcct gtacgatagc
    24661 aaaataaccg ttgccggcag caaggtgcag cggtgagtcg cctactttgt cttgaatgtc
    24721 gacggtggcc ccagcacaaa gcagcgcctg aacgatctca agatgccctt tcgaaacagc
    24781 cagatggaga ggcgtatgac catgggcatc cttgacatca gtaggagcac cgtggctcag
    24841 taacatcttt gcaatcttgc tatatccctt gatagcagct gcatgcagag tcgttctctg
    24901 agatgggcca attgtcacat ccgtaatggt agctccatgc ttcaaaagaa cctccacaac
    24961 gcgatcatgt cctgttataa tggcataatc tagcggacta aatccgctgt tctgccgtgc
    25021 gttgatatca gcacccacat caatgagcag agacaccaca ttgtagtgac cgtaagcagc
    25081 ggcccagtgc aacggcgtgt atccctcatc atcagcggcg cagggatcgg ctccttgctc
    25141 cagataatgc cggacaatgc ttacatgtcc acatgtgact gcagaaaata atatcgtctg
    25201 tccttcttcg cggagactag atgagtacac cgagagagcc agctgggcga acccttccgc
    25261 ggcttgcgcg agagccacga catccggggg tctcaaatac tcaaacagtt ccagaataat
    25321 ctctggggga agtggcagcc cccaccagcg acccatgctg ggtgagagaa ggagtaagga
    25381 gaagttgagt ccaagtggcc tgtggccagt ggcctcccct atcttatttc agggggaaat
    25441 acgaggatta gacgcatcac gtgcggagga gacactgtct gccagaaagg aacatagttt
    25501 gggcagaaaa tcttggatat tttccctgaa catattgtca ttcaaagtgg cctgaatcaa
    25561 tactgaatac tgatagtgga gctgattttg aacagttgtg attccccatg tctgttaact
    25621 cattcctatc attatacatc accaactgtc cactttgcct ctggatatca tcttcacaac
    25681 tcaatctatt acctctgcta ctatccatat gtagatttag ttcggtcagc tttgacataa
    25741 gtataactgg aaagggttaa tcttaatggt tttttacaat ttatttctcc tccaggggtc
    25801 aattgaacat gcttacatga gattattatt tcaggcaaaa tatatggtaa ttattctata
    25861 tcgatctaac tttatttcaa tcaaaatcta aaaggttaat aaaaaaaatc catagggctg
    25921 aataggccgt ggctagaata tattcacttt cagttgttat taacggtgaa ctatatatct
    25981 ctggatataa accactacta ctttcatcca atctatgact agatacgtaa tcccgtatat
    26041 ctcaccaacc agcaatcatt taaaatgata tttcatactc aaaaatgcta gatactaggg
    26101 tatctagtga tattgatatg tctaagaaat gcaactatcc acatgctaat cagttgccgg
    26161 aatgacaccc aaatgcatag acaccacctc ggccaatcct ccaaacgtca acgagggcga
    26221 cagcaagttc tggaatgaga actcaagtcc aacttcctta aatgaccagt tcttcatctc
    26281 cgcaccaatt atactgtcaa ggccatagct agcaatggag ggtccatcga gctcaaagtc
    26341 ctcagccgaa atcagcaaga tactgctaac acgtgaacgg ctgtcatggt agcggtaggt
    26401 gacaacaccg actttagatg cagggatggc gtggagaagg ttgttgactg accaaattcg
    26461 ctgatatcgt gcacagatgc gacgctcttt gtcagcccag ggtatttctg gacgagatct
    26521 agcgccagtt ggagggcgtc agacaccgtc gcggtatgga gtgtcttttc gctggttggc
    26581 atgaatgacg caccacgaga gaaggcaacg ggtctggtgc agaatcgagc aatgtttcat
    26641 ttaagacgaa gacgctgtga gcgggaagcc gcctccacac ttcttgactc gagggagaaa
    26701 agtcgtgggc gaggataacc catctgcagt ccttttcctg caagggtgta cggatacctt
    26761 cgacaaggac actgcgatta tcaatgtcga atctgctaat gtattcctcc tgctcttctg
    26821 ccaggtacgg gcgtaggcgc cgagatagtt gccatacgat aattgtaggg gtcctccacc
    26881 gctctcaaag ggcaacacat cgtaggaaat gttgaaggat ggatcgatct tgtcattgtt
    26941 ggcccggtca agctgcaact gttcttgtat gctggataca cgctgttcca ggaccagaaa
    27001 tcatcgccaa caaaattgga ccattcatcg aacgtgccca cggtgggtcg cgcatatccc
    27061 atgtaaatcg aggctgagcc tgttccctag ccaattcatc ttccggtgac acaaggtcta
    27121 gggaccattc tctacaccgg gccatccagg ccggggccga tgtgtgactt gatccgctgc
    27181 aggttgggag cacggtattc tacggagtag gcaggctgga cagatcattt tgcaatagta
    27241 caatgtagct gaacatgtac aataagatgg tagcaccaat agcaattcct agctgtcaat
    27301 aggcaggtgc taaaggatgc tggctaacct tactgcggaa atacctcaga aggctcccac
    27361 aacatgactc gttcaagacc aacaaaatga ccatgcatcc ttgttcaaaa gcactagaag
    27421 cttccttctc ccaaggcttc gccagcctgg aaacatggac cgtcggggaa tcctcaccga
    27481 gactaaaata gcgccctagt catccagtag ataagcccaa cggtggcgtc acataaatca
    27541 cagtcttact cattctgaga ggtatcgaaa cgtaacaggg gtccggattc tccagtattg
    27601 gtcatggtat ctggacggat tttagtcggg gataacgaat ctgccgccat atatcctgtc
    27661 ccccctgaat agctcaacga gacccctcgt cttctgcatt gtatctac
//
