BGC0000369: hassallidin C biosynthetic gene cluster from Anabaena sp. Syke748
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Location: 1 - 67,299 nt. (total: 67,299 nt).
This entry is originally from NCBI GenBank KJ502174.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
Saccharide
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000369
Short description hassallidin C biosynthetic gene cluster from Anabaena sp. Syke748
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Saccharide (hybrid/tailoring)
Loci NCBI GenBank: KJ502174.1
Compounds
  • hassallidin C
Species Anabaena sp. Syke748 [taxonomy]
References
Chemical products information
hassallidin C
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHZ20758.1
 154 - 1275 (+) phage integrase
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  • AHZ20759.1
 1472 - 2344 (-) IS5 family IS5 ssgr transposase
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  • AHZ20760.1
  • hasA
 2620 - 4380 (-) ABC transporter transmembrane domain/ATP-binding domain protein
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  • AHZ20761.1
  • hasB
 4713 - 6743 (-) alpha amylase catalytic domain-containing protein
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  • AHZ20762.1
  • hasC
 6951 - 7991 (-) methyltransferase domain-containing protein
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  • AHZ20763.1
  • hasD
 8047 - 8835 (-) glycosyl transferase family 2 protein
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  • AHZ20764.1
  • hasE
 8832 - 9344 (-) GtrA-like protein
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  • AHZ20765.1
  • hasF
 9348 - 10988 (-) putative membrane protein
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  • AHZ20766.1
  • hasG
 11023 - 12405 (-) AMP-dependent synthetase/ligase
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  • AHZ20767.1
  • hasH
 12405 - 12740 (-) acyl carrier protein
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  • AHZ20768.1
  • hasI
 12748 - 13854 (-) hypothetical protein
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  • AHZ20769.1
  • hasJ
 13892 - 15223 (-) putative esterase
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  • AHZ20770.1
  • hasK
 15220 - 16560 (-) major facilitator transporter
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  • AHZ20771.1
  • hasL
 16657 - 17421 (-) 3-oxoacyl-acyl-carrier-protein reductase
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  • AHZ20772.1
  • hasM
 17666 - 18238 (+) aspartyl/asparaginyl beta-hydroxylase
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  • AHZ20773.1
  • hasN
 18328 - 27489 (+) non-ribosomal peptide synthase
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  • AHZ20774.1
  • hasO
 27532 - 38469 (+) non-ribosomal peptide synthase
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  • AHZ20775.1
  • hasP
 38488 - 39546 (+) NAD dependent epimerase/dehydratase
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  • AHZ20776.1
  • hasQ
 39630 - 40835 (+) glycosyltransferase MGT family
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  • AHZ20777.1
  • hasR
 40926 - 42032 (-) putative acyltransferase
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  • AHZ20778.1
  • hasS
 42120 - 42644 (-) transcription factor jumonji domain-containing protein
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  • AHZ20779.1
  • hasT
 42721 - 43488 (-) glycosyltransferase DXD motif-containing protein
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  • AHZ20780.1
  • hasU
 43558 - 43779 (-) hypothetical protein
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  • AHZ20781.1
  • hasV
 43869 - 50324 (-) non-ribosomal peptide synthase
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  • AHZ20782.1
  • hasW
 50526 - 50897 (+) hypothetical protein
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  • AHZ20783.1
  • hasX
 50903 - 51844 (+) glycosyl transferase family 2 protein
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  • AHZ20784.1
  • hasY
 51868 - 60414 (+) non-ribosomal peptide synthase
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  • AHZ20785.1
  • hasZ
 60476 - 61759 (+) major facilitator transporter
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  • AHZ20786.1
 61873 - 62229 (+) IS1380 family transposase
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  • AHZ20787.1
 62268 - 63722 (+) hypothetical protein
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  • AHZ20788.1
 63681 - 64994 (-) CemA family protein
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  • AHZ20789.1
 65053 - 67245 (+) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? yes
Release type
  • Hydrolysis
NRP-synthases
Gene Modules
hasG
Module 0
Specificity: 2,3-dihydroxyhexadecanoic acid
Evidence for specificity:
  • Sequence-based prediction
hasN
Module 3
Specificity: threonine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: LCL
Module 4
Specificity: tyrosine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: DCL
hasO
Module 5
Specificity: threonine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: DCL
Module 6
Specificity: glutamine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: DCL
Module 7
Specificity: glycine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: DCL
hasV
Module 1
Specificity: threonine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: Starter
Module 2
Specificity: threonine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: DCL
hasY
Module 8
Specificity: threonine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: LCL
Modification domains: Methylation
Module 9
Specificity: glutamine / tyrosine
Evidence for specificity:
  • Sequence-based prediction
Condensation domain type: LCL
Saccharide-specific information
Subclass hybrid/tailoring
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: BAJIZJS2YANDM4M7JHS5DFUK, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: 3UOU7PODQJXIM6BEPUHHRRA5, no GDPR consent given).
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Remove negative molecular mass
  • Corrected NRP module activity
  • Updated NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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