LOCUS       BGC0000384             17000 bp    DNA     linear   BCT 20-OCT-2004
DEFINITION  Lyngbya majuscula lyngbyatoxin biosynthetic gene cluster, complete
            sequence.
ACCESSION   BGC0000384
VERSION     BGC0000384
KEYWORDS    .
SOURCE      Lyngbya majuscula
  ORGANISM  Lyngbya majuscula
            Bacteria; Cyanobacteria; Oscillatoriophycideae; Oscillatoriales;
            Oscillatoriaceae; Lyngbya.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 18:52:14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17000
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..17000
                     /db_xref="taxon:158786"
                     /mol_type="genomic DNA"
                     /organism="Lyngbya majuscula"
     protocluster    1..17000
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2739:10182]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2740..10182
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..17000
                     /SMILES="NC([*])C(=O)NC(Cc1ccccc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="neighbouring"
                     /product="NRPS"
                     /product="indole"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..17000
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000384"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..17000
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="NRPS"
                     /product="indole"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1730..17000
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[11729:12902]"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11730..12902
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
     cand_cluster    1730..17000
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             2740..10182
                     /NRPS_PKS="Domain: AMP-binding (22-416). E-value: 3.3e-105.
                     Score: 343.8. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /NRPS_PKS="Domain: nMT (504-728). E-value: 7e-108. Score:
                     352.4. Matches aSDomain: nrpspksdomains_AAT12283.1_nMT.1"
                     /NRPS_PKS="Domain: PCP (940-1008). E-value: 5.9e-25. Score:
                     79.1. Matches aSDomain: nrpspksdomains_AAT12283.1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1023-1321). E-value:
                     2.9e-106. Score: 346.7. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1491-1896). E-value:
                     1.4e-113. Score: 371.4. Matches aSDomain:
                     nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2004-2070). E-value: 2e-25. Score:
                     80.6. Matches aSDomain: nrpspksdomains_AAT12283.1_PCP.2"
                     /NRPS_PKS="Domain: TD (2108-2352). E-value: 8.3e-85. Score:
                     275.7. Matches aSDomain: nrpspksdomains_AAT12283.1_TD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     355; E-value: 1.2e-107)"
                     /gene_kind="biosynthetic"
                     /note="NRPS with A-NM-PCP-C-A-PCP-Red domain organization"
                     /product="LtxA"
                     /protein_id="AAT12283.1"
                     /sec_met_domain="Condensation (E-value: 2.3e-69, bitscore:
                     221.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-125, bitscore:
                     406.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-19, bitscore:
                     56.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.1e-72, bitscore:
                     231.3, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.3e-09,
                     bitscore: 25.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMNQPWSGSRRAIVNSTLPQAFEDRVNRTPNQIAIVFDELHLSY
                     TQLNVKANYLANLLIRSGVEPKTPIAIQIERSIELVVAVLAVLKAGAIYVPLDPRLPLA
                     RVHWILDETRAQTLLTISNSKNLDKIKNIQTTIRVDVHLKKEDPDSPAIDTQPDDLAHI
                     MYTSGSTGHPKGVAITHRAILEFVADRCWKNELQERVLFHSSLGFDISNYELWVPLLRS
                     GQLVMAPSGPLDVSTLKQVIQKQSITSLFLTTSLFNLVTEENPRCLAGVQQVWIGGEQA
                     SVAAIQRMWDACPEITVVNGYGPTETTTYVTLYTIESRPQGNRVPIGRPMENTQVYVLD
                     EELKPVPSGTPGEIYLAGTGLARGYFGQPSLTSTRFLANPFGLPGSRMYRTGDLGVWID
                     SDQLVCLGRSDRQVKIRGIRIEPSEIEAELRNHPEIGEAVVTVREDSPDEKRLIAYLIA
                     KTIESQTQKIQGEQLVAWRQIYDSLYENDTSSPLGSDFSGWHSSYDGCPIPLEQMQEWQ
                     EMTLQEIRGLQPRRILEIGVGTGLLLAQLAPDCESYWGTDFSASLIERLRHRVALEPSL
                     AGRVELRSQSADAIEGLPREHFDTVILNSVIQYFPNPTYLLDVLNKVVDLLVPGGYIFI
                     GDIRNLRLLHCFHTEVQLRRTDLKTLNTLALQAAVEHSVVMEDELLVDPEFFSALGQRR
                     SDIDYVDVRVKRGWHHNEMSQYRYNVILHKCSTTTEPIPTVEWHPIAWGSKFTTLEQLI
                     DYLKQEIPSHLKLVNVPNCRVTPALKAIQQLNAGYDLDVVQDHLFSGDSAACNPEDFYK
                     IGELLDYQVFVTWSNTDIGHLDILFCPQNSQLNNIRVFRTDSPLHNNQGVYDSLLFYMN
                     SPSVSYHAGTFLESVRTHLSERLSQSMIPTAFVILDTFPLTVNGKVDRAALPVPHIGST
                     QNGRAPRNAVEERMCGLFAQILGVTQVTIDDNFFDLGGHSLSVMRLLSRIRSCFDVELA
                     VANVFASPTVAELVKHLTKAEPGRPQLMGMNRPSVVPLSFSQQRLWFIYAFDTSSVIYN
                     VPIAFELAGSINQIAMEMALHDVISRHDSLHTVFQEISGVPRQVLLNPGQFELTITHTS
                     VTELDQKLLDSSQRPFDLSTEIPIRAELFVLGDDRCVLLILLHHITCDGWSFAPLWRDL
                     SEAYATRSQGLIPDWTPLPVQYADYTLWQRRLLGQDIKPDSIITHQLDYWRKNLAELPE
                     LVSLPGDRPRSAVPSFRGALIPFRLSPELHHGAINLAQQQGTSLFMVLHAVLAVLLTRL
                     GAGTDLPIGTPVANRTDDALEDLVGFFVNLLVLRTDTSGDPSFSDLLARIRDLDIAAYA
                     HQDIPFELLVEKLRPVRSITHHPFFEILLALQSAPENQLKLSGVKISHKQVHLGTCRFD
                     LVMNLDEHRHQDGTLLGIDGLVEYRTDLYDRKTIQTFIDRFLRLLTGAIADPQQRISRL
                     NLLSPEEHHQLLIEWNDTDHSISPRPFPDLFEAQVAQTPTANALVFGALHLSYQELNAR
                     ANQLAHQLIYQGIGPGQVIAIDVPRSPEWVIAVLAVLKAGAAYLPLDPSYPASRIIYML
                     EDVQPCLLITTTNSLISNPKLNIPKLQLDSFPWEASLNVTSEKQDYGLQANIEDNRGTQ
                     PLHVSDPAYIIYTSGSTGKPKGVVVTHAGISSMVATQIKYFEVTPESRILQFSSLSFDG
                     VVWELCSALLTGATLVMAPSERVQPGPELIQLIGDYHVTHAVLPPAVLMVLSPDNIPSL
                     THLIVSGEAASGELVKRWSVGRCLINGYGPTETTVCATLSSPLSGNGIPPIGRAVINVQ
                     CYVLDDQLQLLPPGAIGELYISGPGLARGYLNQPQLTAERFLANPFRDIGSRMYRTGDL
                     VRWRNHGELEFVGRADNQVKIRGFRVELGEVETALTNCPPVSDALAMVREDRPGEKFLV
                     AYVVGQDSMDTDALRAQLVNDLPPYLIPGAIVTLKKFPLTVNGKIDRKALPVPKFTSIA
                     EGRVPKTPTQIGLCTLFAELLGVDQVTIDDPFFALGGHSLLATQLVSQIRQRFGISLPV
                     QTVFERQTVADLAIVVDREAPIVSTSIDLAAEVVLNPQIAPYQSRPVELDRNTHPASVL
                     LTGATGFLGAYLLYELLKQTDANVFCLVRSNHSEAAYQRIHSTLKFYQLWSESWRSRII
                     PVCGDLSQPSLGLSAEEFSKLTELIDAIYHNGAQVSAIEPYTYLKPTNVLGTSELLDFA
                     ARCRVKPLHFVSTAAVAVSSKGNPDIIYENFRLGADSVLPSGYVSSKWVAEELVWVASD
                     RGLPVTVHRPGRISGDTTTGIGNTDDTFWQIVRAIVVLGVVPDIVYQDDAGIDLMPVDR
                     VASAIVHLSRHKQSISKVHHLTCPTIVKLDVVFNELSKLGYQLTTVSYSEWVKQLEQYV
                     DQAPGGHSLASATVLSRTLPKLIELSQICFDQSNTLTGLAEAPFKFPCIDRHLVRGYLT
                     YFINSKFFPQITYTGK"
     aSDomain        2806..3987
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /evalue="3.30E-105"
                     /label="AAT12283.1_AMP-binding.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="416"
                     /protein_start="22"
                     /score="343.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEDRVNRTPNQIAIVFDELHLSYTQLNVKANYLANLLIRSGVEPK
                     TPIAIQIERSIELVVAVLAVLKAGAIYVPLDPRLPLARVHWILDETRAQTLLTISNSKN
                     LDKIKNIQTTIRVDVHLKKEDPDSPAIDTQPDDLAHIMYTSGSTGHPKGVAITHRAILE
                     FVADRCWKNELQERVLFHSSLGFDISNYELWVPLLRSGQLVMAPSGPLDVSTLKQVIQK
                     QSITSLFLTTSLFNLVTEENPRCLAGVQQVWIGGEQASVAAIQRMWDACPEITVVNGYG
                     PTETTTYVTLYTIESRPQGNRVPIGRPMENTQVYVLDEELKPVPSGTPGEIYLAGTGLA
                     RGYFGQPSLTSTRFLANPFGLPGSRMYRTGDLGVWIDSDQLVCLGRSDRQVKIR"
     aSModule        2806..5763
                     /complete
                     /domains="nrpspksdomains_AAT12283.1_AMP-binding.1"
                     /domains="nrpspksdomains_AAT12283.1_nMT.1"
                     /domains="nrpspksdomains_AAT12283.1_PCP.1"
                     /locus_tags="AAT12283.1"
                     /monomer_pairings="X -> NMe-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2992..3033
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0001"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="AAT12283.1"
                     /protein_end="98"
                     /protein_start="84"
                     /score="18.0"
                     /tool="antismash"
                     /translation="LAVLKAGAIYVPLD"
     CDS_motif       3220..3279
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0002"
                     /evalue="6.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="AAT12283.1"
                     /protein_end="180"
                     /protein_start="160"
                     /score="24.9"
                     /tool="antismash"
                     /translation="AHIMYTSGSTGHPKGVAITH"
     CDS_motif       3643..3666
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0003"
                     /evalue="4.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="AAT12283.1"
                     /protein_end="309"
                     /protein_start="301"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPTETTT"
     CDS_motif       3778..3867
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0004"
                     /evalue="8.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="AAT12283.1"
                     /protein_end="376"
                     /protein_start="346"
                     /score="40.5"
                     /tool="antismash"
                     /translation="PSGTPGEIYLAGTGLARGYFGQPSLTSTRF"
     CDS_motif       3952..4017
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0005"
                     /evalue="5.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="AAT12283.1"
                     /protein_end="426"
                     /protein_start="404"
                     /score="31.4"
                     /tool="antismash"
                     /translation="CLGRSDRQVKIRGIRIEPSEIE"
     aSDomain        4252..4923
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_nMT.1"
                     /domain_subtype="nMT"
                     /evalue="7.00E-108"
                     /label="AAT12283.1_nMT.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="728"
                     /protein_start="504"
                     /score="352.4"
                     /tool="antismash"
                     /translation="GCPIPLEQMQEWQEMTLQEIRGLQPRRILEIGVGTGLLLAQLAPD
                     CESYWGTDFSASLIERLRHRVALEPSLAGRVELRSQSADAIEGLPREHFDTVILNSVIQ
                     YFPNPTYLLDVLNKVVDLLVPGGYIFIGDIRNLRLLHCFHTEVQLRRTDLKTLNTLALQ
                     AAVEHSVVMEDELLVDPEFFSALGQRRSDIDYVDVRVKRGWHHNEMSQYRYNVILHKCS
                     TT"
     CDS_motif       5482..5508
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0006"
                     /evalue="5.80E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="AAT12283.1"
                     /protein_end="923"
                     /protein_start="914"
                     /score="3.6"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     CDS_motif       5521..5583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0007"
                     /evalue="1.30E+01"
                     /label="C5_DCL_263-294"
                     /locus_tag="AAT12283.1"
                     /protein_end="948"
                     /protein_start="927"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GSTQNGRAPRNAVEERMCGLF"
     aSDomain        5560..5763
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_PCP.1"
                     /evalue="5.90E-25"
                     /label="AAT12283.1_PCP.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="1008"
                     /protein_start="940"
                     /score="79.1"
                     /tool="antismash"
                     /translation="EERMCGLFAQILGVTQVTIDDNFFDLGGHSLSVMRLLSRIRSCFD
                     VELAVANVFASPTVAELVKHLTK"
     CDS_motif       5623..5652
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0008"
                     /evalue="5.00E-02"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="971"
                     /protein_start="961"
                     /score="7.4"
                     /tool="antismash"
                     /translation="NFFDLGGHSL"
     aSDomain        5809..6702
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.90E-106"
                     /label="AAT12283.1_Condensation_LCL.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="1321"
                     /protein_start="1023"
                     /score="346.7"
                     /tool="antismash"
                     /translation="VVPLSFSQQRLWFIYAFDTSSVIYNVPIAFELAGSINQIAMEMAL
                     HDVISRHDSLHTVFQEISGVPRQVLLNPGQFELTITHTSVTELDQKLLDSSQRPFDLST
                     EIPIRAELFVLGDDRCVLLILLHHITCDGWSFAPLWRDLSEAYATRSQGLIPDWTPLPV
                     QYADYTLWQRRLLGQDIKPDSIITHQLDYWRKNLAELPELVSLPGDRPRSAVPSFRGAL
                     IPFRLSPELHHGAINLAQQQGTSLFMVLHAVLAVLLTRLGAGTDLPIGTPVANRTDDAL
                     EDLVGFFVNLLVLRTDT"
     aSModule        5809..9795
                     /complete
                     /domains="nrpspksdomains_AAT12283.1_Condensation_LCL.1"
                     /domains="nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /domains="nrpspksdomains_AAT12283.1_PCP.2"
                     /domains="nrpspksdomains_AAT12283.1_TD.1"
                     /final_module
                     /locus_tags="AAT12283.1"
                     /monomer_pairings="phe -> phe"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       5875..5985
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0009"
                     /evalue="1.80E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="AAT12283.1"
                     /protein_end="1082"
                     /protein_start="1045"
                     /score="33.2"
                     /tool="antismash"
                     /translation="IYNVPIAFELAGSINQIAMEMALHDVISRHDSLHTVF"
     CDS_motif       6184..6249
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0010"
                     /evalue="5.20E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="AAT12283.1"
                     /protein_end="1170"
                     /protein_start="1148"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LHHITCDGWSFAPLWRDLSEAY"
     CDS_motif       6298..6336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0011"
                     /evalue="5.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="AAT12283.1"
                     /protein_end="1199"
                     /protein_start="1186"
                     /score="15.7"
                     /tool="antismash"
                     /translation="QYADYTLWQRRLL"
     CDS_motif       6604..6693
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0012"
                     /evalue="1.00E-14"
                     /label="C5_LCL_267-296"
                     /locus_tag="AAT12283.1"
                     /protein_end="1318"
                     /protein_start="1288"
                     /score="46.8"
                     /tool="antismash"
                     /translation="DLPIGTPVANRTDDALEDLVGFFVNLLVLR"
     CDS_motif       6754..6861
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0013"
                     /evalue="2.30E-15"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="AAT12283.1"
                     /protein_end="1374"
                     /protein_start="1338"
                     /score="48.9"
                     /tool="antismash"
                     /translation="IAAYAHQDIPFELLVEKLRPVRSITHHPFFEILLAL"
     aSDomain        7213..8427
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_AMP-binding.2"
                     /evalue="1.40E-113"
                     /label="AAT12283.1_AMP-binding.2"
                     /locus_tag="AAT12283.1"
                     /protein_end="1896"
                     /protein_start="1491"
                     /score="371.4"
                     /specificity="consensus: phe"
                     /tool="antismash"
                     /translation="FEAQVAQTPTANALVFGALHLSYQELNARANQLAHQLIYQGIGPG
                     QVIAIDVPRSPEWVIAVLAVLKAGAAYLPLDPSYPASRIIYMLEDVQPCLLITTTNSLI
                     SNPKLNIPKLQLDSFPWEASLNVTSEKQDYGLQANIEDNRGTQPLHVSDPAYIIYTSGS
                     TGKPKGVVVTHAGISSMVATQIKYFEVTPESRILQFSSLSFDGVVWELCSALLTGATLV
                     MAPSERVQPGPELIQLIGDYHVTHAVLPPAVLMVLSPDNIPSLTHLIVSGEAASGELVK
                     RWSVGRCLINGYGPTETTVCATLSSPLSGNGIPPIGRAVINVQCYVLDDQLQLLPPGAI
                     GELYISGPGLARGYLNQPQLTAERFLANPFRDIGSRMYRTGDLVRWRNHGELEFVGRAD
                     NQVKIR"
     CDS_motif       7399..7440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0014"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="AAT12283.1"
                     /protein_end="1567"
                     /protein_start="1553"
                     /score="18.2"
                     /tool="antismash"
                     /translation="LAVLKAGAAYLPLD"
     CDS_motif       7675..7734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0015"
                     /evalue="9.90E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="AAT12283.1"
                     /protein_end="1665"
                     /protein_start="1645"
                     /score="33.4"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVVVTH"
     CDS_motif       8089..8115
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0016"
                     /evalue="2.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="AAT12283.1"
                     /protein_end="1792"
                     /protein_start="1783"
                     /score="7.9"
                     /tool="antismash"
                     /translation="YGPTETTVC"
     CDS_motif       8218..8307
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0017"
                     /evalue="1.00E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="AAT12283.1"
                     /protein_end="1856"
                     /protein_start="1826"
                     /score="59.3"
                     /tool="antismash"
                     /translation="PPGAIGELYISGPGLARGYLNQPQLTAERF"
     CDS_motif       8392..8457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0018"
                     /evalue="7.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="AAT12283.1"
                     /protein_end="1906"
                     /protein_start="1884"
                     /score="37.2"
                     /tool="antismash"
                     /translation="FVGRADNQVKIRGFRVELGEVE"
     CDS_motif       8665..8691
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0019"
                     /evalue="1.50E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="AAT12283.1"
                     /protein_end="1984"
                     /protein_start="1975"
                     /score="5.2"
                     /tool="antismash"
                     /translation="GKIDRKALP"
     aSDomain        8752..8949
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_PCP.2"
                     /evalue="2.00E-25"
                     /label="AAT12283.1_PCP.2"
                     /locus_tag="AAT12283.1"
                     /protein_end="2070"
                     /protein_start="2004"
                     /score="80.6"
                     /tool="antismash"
                     /translation="LCTLFAELLGVDQVTIDDPFFALGGHSLLATQLVSQIRQRFGISL
                     PVQTVFERQTVADLAIVVDRE"
     CDS_motif       8809..8835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0020"
                     /evalue="1.00E-01"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="2032"
                     /protein_start="2023"
                     /score="6.5"
                     /tool="antismash"
                     /translation="FFALGGHSL"
     aSDomain        9064..9795
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12283.1_TD.1"
                     /evalue="8.30E-85"
                     /label="AAT12283.1_TD.1"
                     /locus_tag="AAT12283.1"
                     /protein_end="2352"
                     /protein_start="2108"
                     /score="275.7"
                     /tool="antismash"
                     /translation="VLLTGATGFLGAYLLYELLKQTDANVFCLVRSNHSEAAYQRIHST
                     LKFYQLWSESWRSRIIPVCGDLSQPSLGLSAEEFSKLTELIDAIYHNGAQVSAIEPYTY
                     LKPTNVLGTSELLDFAARCRVKPLHFVSTAAVAVSSKGNPDIIYENFRLGADSVLPSGY
                     VSSKWVAEELVWVASDRGLPVTVHRPGRISGDTTTGIGNTDDTFWQIVRAIVVLGVVPD
                     IVYQDDAGIDLMPVDRVASAIV"
     CDS_motif       9961..9981
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12283.1_0021"
                     /evalue="4.10E+01"
                     /label="PCP_mC"
                     /locus_tag="AAT12283.1"
                     /protein_end="2414"
                     /protein_start="2407"
                     /score="-1.1"
                     /tool="antismash"
                     /translation="APGGHSL"
     CDS             10185..11567
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 85.8; E-value:
                     2.1e-26)"
                     /gene_kind="biosynthetic-additional"
                     /note="P450 monooxygenase"
                     /product="LtxB"
                     /protein_id="AAT12284.1"
                     /sec_met_domain="p450 (E-value: 8.1e-28, bitscore: 85.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNPFADPSRDYWVLCNAEGQYSLWPTSLEIPEGWQTAFGPESWQ
                     NCLDNVEKNWTDMRPLSLLGQRKCPVPYPFREYVALNMDPIYASLQQRDEMLRISVPYG
                     DDAWLASSYKHVKCVIQDTRFSRETTKYDEARLTPIPIRTSVLGMDPPDHTRLREALAA
                     ALTPSHVEQMKPWITSMTEQLIDDFVAQGPPADLVEQFALPFTGHITCELMGIPLEDRP
                     QFKAWCDGFSSTSSLTKEEVEVRMQAMYTYITELVGRRRESPSDDIISKLLQPEDKRLE
                     LSEIELIDLATILLLAGYDSTAMELANAIFVLLTHPEQTQLIREQPKLMPQAVQELLRY
                     IPIDAHVTFARYATEDVQVGNTLVRTGDAILASFPSANHDPAIFEDPHTFNIMRPRKPN
                     FGLGTGIHSCAGKLLAVVELEIALSVLIRRLPTLRLAIPAEEVPWQPGSLLRSTSKLPA
                     EW"
     CDS             11730..12902
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /note="prenyltransferase"
                     /product="LtxC"
                     /protein_id="AAT12285.1"
                     /sec_met_domain="indole_PTase (E-value: 2e-100, bitscore:
                     324.3, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKIAVSEYASDSFGKADTRAYDDLPIFASNYYSREASYIDIAC
                     DKLHRACDGLAFPAERRDTIVAFLRKLCTPWGNALASAPQHFSNVSVEGMPFELSLAWS
                     NGRGHELRMSFEVLHSPHSLSNNLEAARRFVRELPSIPELAPDISIENFLLIEDLVTAS
                     EPTDFITPMGQGIAWLSDRPNPVMKTYLNLNIAGFESGPERTKEAMTRLGAGSAWQSLC
                     SYLTSLGVSVVPLFLALDLAHSDHPRLKIYLPHTGVDAGMIDKQAEIAQTHVNGKFKEA
                     LLEITGHTTPDWRKVPVTCYTLVPGQDRPVAATLYVPLNPNIENDAVAQERVCAFSQSQ
                     GVDPSPYESLLKAISDKPLSQLSTHNFVAYRPGKDPRFSVYLAPGVYKRS"
     CDS             13259..13999
                     /NRPS_PKS="Domain: PKS_KR (7-167). E-value: 2.9e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_AAT12286.1_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     237.3; E-value: 3e-72)"
                     /gene_kind="biosynthetic-additional"
                     /note="reductase/oxidase"
                     /product="LtxD"
                     /protein_id="AAT12286.1"
                     /sec_met_domain="adh_short (E-value: 2.6e-40, bitscore:
                     126.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-37, bitscore:
                     118.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLQGKVAIITGGSRGIGRAIAERLAQDGATIMLTYLRNKALAE
                     AVVAQIETQGGQARAMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFS
                     IHDWQRVFAVNSTAPFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQ
                     LTRVAAWELADRGITVNSVSPGPTDTDLLRTGNPPEVLEQAIAMTPLGRLGQPKDIADV
                     VAFLVGNDGRWITGQNLRVTGGLI"
     aSDomain        13280..13759
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAT12286.1_PKS_KR.1"
                     /evalue="2.90E-16"
                     /label="AAT12286.1_PKS_KR.1"
                     /locus_tag="AAT12286.1"
                     /protein_end="167"
                     /protein_start="7"
                     /score="51.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIITGGSRGIGRAIAERLAQDGATIMLTYLRNKALAEAVVAQIE
                     TQGGQARAMAVDLAQPADIERLFEMTEATWQRLDILVNSAAELQTGSIESFSIHDWQRV
                     FAVNSTAPFLTIQQAARRLSAHGRIVNVSTINTVLAEPGIAAYAASKGSLEQLTRV"
     CDS_motif       13286..13354
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AAT12286.1_0001"
                     /evalue="3.00E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AAT12286.1"
                     /protein_end="32"
                     /protein_start="9"
                     /score="23.1"
                     /tool="antismash"
                     /translation="IITGGSRGIGRAIAERLAQDGAT"
ORIGIN
        1 cctaatttat tatggtaatc aatatatata gtagggagta gggagtaggg agtaagaaat
       61 accaagcgtg aaaaaagaat gttacggata attagagtaa tttctagact ttacctatag
      121 tatttctttg actaaaaatc aatcttatcc ctaataaatg ccgataaact cttccttcta
      181 tacatcgtta attcgacatt tttatagcac tacgcaaata ggttaggaca tttataaatg
      241 ctcaaactca gtcagatatt acttttaact tttgactttt gacttttgac ttgcgcgtag
      301 cgctatacta cctgaatctt agtaagaact ttgctattta tagtaactat ttatcaaact
      361 actagaacag gaaataggga aagataaagt gatctttttc ttttgggttt aataccccgt
      421 cgtctacgcg gtgtttacaa ttggttgagg ttataaaaaa cctgaagttg taggtcgttc
      481 actgtctcca tccacttttt cctttttctt tcttccttct tgcttttttt tagtcataag
      541 acaaaaagag tatcaatcta gcaagcttaa ttaatttgat aaaaaatata tctagcattt
      601 atcctacatt acgcacgaca aaatgtagta tgcaaagagg ggaaaacttg agtaagtatt
      661 tagacttata gtatggggta ggaggcgata tagctaccgc taggctccgc caacgcaaat
      721 caataggtac ttaacccatc ctcaccctat ttttttttga gtgatgttgg ctgaaaagct
      781 gatcctaaag agatttcaac ttgtttgtta ttcctgcaat acttcataaa tgccttatat
      841 aatgatatca gttgctcaaa gttaccaata gatatcttca aaaattgcca aagtttctct
      901 atcacttgag cgatcgcatc ttaatcattg ccaagtgctt tgattttaca ctactattca
      961 attgttgatt attttagcgc tgtaactgct tctatctcaa gtttctcaac tgagtagata
     1021 gtatctttga caacttggag gaaaaaactt caataattct aaacggtctg gagtgagatt
     1081 agatatgctc ttaactccag aattaatcaa taaatgaatc gactgaaaac attgaaatat
     1141 ccaacgcaaa gtcggtcgat ttgtcggacg acccaattga ttttttacac tagatttagt
     1201 ccgatttaaa gttgggcgta gttgacgctg gcctaaagtg taaactcata aacataaccc
     1261 cataattaac cccaaagctt cgattctatg gggtgattta aggaagacac tatcggttaa
     1321 aaatagaggg tatgcccaga aacctaaaac ccctctcaac agattgttgt cctttatatt
     1381 tagacagcat ttcttctttc gttagttcca tcttatccag gacatttgtt gctaatataa
     1441 atcgacctgc tcgttttttt tctagttcta tttttgactc tcttaagccc acttgaactt
     1501 ggacttcata agtaaaatct gtatcagatt tccctcaaaa aatcgactaa ataaatacaa
     1561 tggggacgaa actaatccta acccatttaa gagcattcct ttgactactt gaccccctgt
     1621 tattttttct ggttgttctc caagtaattg atttattttc tgttctatac caatctcatc
     1681 gataattcct gctactaatc cgatctgggt ctatattact aacttctatt gacattttct
     1741 cctctttttt tatgttcacc ttctgtctag aattacagtt tgaggttttt ttttcttgag
     1801 tctaaatact gactcaagtt ttaccatctt tgcgtactac attttgtcgt gcgggatgtg
     1861 ggatttatca ttccattgat gtagcagttt tacctgaaaa aaccggaaca ttattgcata
     1921 ttttttattc tataaaatca acaatcatat ctcaatcatc aagctttaat atcctataga
     1981 ttaacccaca aatattaagg atattatgac aaatttctca tggcttttta aaattcttaa
     2041 cctaccacct acaactttct tcaaggttta tttaggtata gcagtcgaag gaaaggttag
     2101 gaaagatcaa aagcttaaaa ctcagacaac gtaagatttt tccttcttcc ttctgctata
     2161 tcagtaataa aactgagtta tctatccgga tttatcaaca tagtattgat agacatacca
     2221 ttagtgatga gattcagagc accttggcgt aaatcttgac tgtaagggag taccataaca
     2281 ctcacgctct tattttaaga taggaatatc ataagttata aactgtaaat tgtaaattcc
     2341 attacacgca tcctgaaaac tttgacgaag gcccggtcgc gtaatttatg aaaaaagcag
     2401 gtcatgcagc caagataatg ctacatcaat cctttgtatg tagtatgtaa atacaccagc
     2461 gctcatggct atacattttg aagtgcggaa tgtgggttaa aagatactat tcttgagatt
     2521 ttagggtggt gattgccacc ttactaattc tgccaaggca gttcataaga acgctcaaat
     2581 aaggtgattc ggttatacac acttttgcca acttgtatag taggaaactt ctacctgtat
     2641 gtaattccca caggaatagt ataataatgt ttatatttaa aatattcctt ataccatcaa
     2701 gatcctttga ttttgagggc tagataaaat tatcccccta tgattatgaa tcaaccttgg
     2761 agtggaagta ggcgggcgat agtaaattcg actttacccc aagcatttga ggatcgagtt
     2821 aaccgaactc caaatcagat tgccatcgtt tttgacgaac ttcacctgtc ctacacccag
     2881 cttaatgtta aagctaatta cttagctaat ctcttaattc gttctggtgt tgaaccaaaa
     2941 actcctattg ccattcagat agagcgttcg attgagttag tggttgctgt ccttgctgtg
     3001 cttaaagcag gtgccatcta tgttcctcta gacccccgtc tacctctagc gcgagttcat
     3061 tggatattag atgaaacaag ggcacaaaca ttactgacta taagtaattc aaagaatcta
     3121 gacaagatca aaaatattca aacaacaatt agagtagatg tccatttaaa aaaggaagat
     3181 ccagatagtc ctgctataga tacgcaaccc gatgatcttg ctcatattat gtacacctca
     3241 ggctcgacag ggcatcctaa aggggtcgct attacccatc gagccatttt agaattcgtt
     3301 gcggatcggt gttggaaaaa tgaacttcag gagcgagtcc tatttcacag ttctctaggc
     3361 tttgatatct caaattatga actgtgggtg cctcttttac gatctggaca gttagttatg
     3421 gccccttctg gacccttgga tgtttctact cttaaacaag ttatccagaa gcaatctatt
     3481 acatctttat tcttaactac ttcattattc aatctagtta ctgaggaaaa tcccagatgc
     3541 cttgcaggtg ttcaacaagt atggattgga ggggaacaag cttcagtagc tgctattcag
     3601 cggatgtggg atgcttgccc tgagattact gtggtcaatg gttatggtcc tacagagacc
     3661 accacatatg tcacccttta tactattgaa agtcgccctc agggcaatcg agtcccgatc
     3721 ggtaggccga tggaaaatac ccaggtctat gtacttgacg aggaactaaa acccgttcct
     3781 tccggtacac caggagaaat ctatctggca ggaacaggtc ttgcacgagg ctactttggt
     3841 caaccaagtt taacatccac acggttcctt gctaatccct ttgggctacc aggatcgcgg
     3901 atgtatcgca ctggtgattt aggagtgtgg attgactcgg atcagcttgt ctgtcttggt
     3961 cgctctgatc gacaagttaa gatccgtggc attcgcattg aacctagcga aatagaggca
     4021 gaactccgca atcatccaga gattggtgaa gcagtcgtta cagttcgcga ggattctcca
     4081 gatgaaaagc gcttgattgc ctacctaatc gccaaaacga ttgaatcaca aacgcagaaa
     4141 attcaggggg aacaactggt agcttggcgt caaatctatg actcgctcta cgaaaatgat
     4201 acttcttctc ctttgggatc ggatttttca ggttggcaca gtagctatga cggttgtcct
     4261 attcccttag aacagatgca ggaatggcag gagatgacac tgcaggagat tcgtgggctt
     4321 cagcctcggc gaatcttgga aattggagtt ggtactggtc tgttgctagc tcaattagct
     4381 ccagactgtg agtcttattg gggaactgat ttctcggcat ctttaattga aaggttacgt
     4441 catcgggttg cccttgagcc atccctagca ggtcgtgtag agcttcgctc tcagagtgct
     4501 gatgcgatcg aagggttacc tcgggagcat ttcgatactg taattctcaa ttctgtaatt
     4561 cagtattttc ctaatcctac ctatttgctt gatgttctga acaaggtggt agatttgctt
     4621 gttccaggtg gttatatttt cattggtgac attcggaact tgcgtctttt gcactgtttt
     4681 cacactgaag ttcaactgcg gcgtactgac ctcaaaactc tcaacaccct cgcgttacaa
     4741 gcagctgttg aacatagtgt agtgatggaa gatgaactgt tagtcgatcc tgagtttttt
     4801 tcagctttag gtcaaagacg atcggacatt gactatgtag atgtgcgagt taaaaggggt
     4861 tggcaccata atgaaatgtc tcagtatcgt tacaacgtta tcctccacaa atgctcgacc
     4921 acaacagaac ctatacctac tgttgagtgg catccgatcg cttggggatc aaaatttaca
     4981 acccttgaac agttgattga ttatcttaaa caggagatac catcccacct aaaattagtc
     5041 aatgtgccca actgtcgcgt tactcctgct cttaaagcaa tacaacagtt gaatgcgggt
     5101 tacgatcttg atgttgtgca agatcatcta ttctctggag actctgctgc ttgcaaccca
     5161 gaagacttct ataagattgg agagttattg gattatcaag tttttgtaac ttggtctaat
     5221 acagacatag gccatcttga catcctgttt tgtccccaga atagtcagtt gaataacatc
     5281 agagtcttca ggaccgatag tcctcttcat aataatcagg gggtatacga ttccttattg
     5341 ttttacatga actctccctc tgtctcatac catgcaggaa catttctaga atcagtgcgg
     5401 actcatctga gtgaaaggtt atctcagtcg atgataccca ctgcctttgt cattctggat
     5461 acttttccgt tgactgtaaa tggcaaagtc gatcgtgctg ctttacctgt tccccatatt
     5521 ggttccactc agaatggacg cgcccccaga aatgctgttg aagagcgtat gtgtggcttg
     5581 ttcgctcaaa ttctgggcgt tactcaagtt acaattgatg ataatttttt tgatcttggt
     5641 gggcattctt tatctgtgat gcggttatta agccgtatcc gctcatgctt tgatgtggaa
     5701 ctagctgttg ccaatgtttt tgcttcacca acagtcgctg aactggtcaa acatctaacc
     5761 aaagcagaac cagggcgacc tcaactcatg ggtatgaacc gccccagtgt tgtaccattg
     5821 tctttttctc aacaacgtct gtggtttatc tatgcttttg atacttctag tgtaatttat
     5881 aatgtcccca tcgcttttga gctggctggc tccatcaatc aaattgcgat ggagatggct
     5941 ttacatgacg tcatctccag acatgatagc ttacatactg tctttcagga aattagcggt
     6001 gtaccacgcc aggttctatt gaatccgggt cagtttgaat tgactatcac tcacacttct
     6061 gtaacagaac tggatcagaa acttctggac agtagtcagc gaccttttga cctcagtact
     6121 gaaattccaa tccgagcaga actatttgtc ctgggagacg atcgatgtgt cctcctcatt
     6181 cttctacacc atattacctg cgatggatgg tcttttgccc ccttatggcg cgatctttcg
     6241 gaggcttatg ccacccgttc ccagggtctc atccctgact ggacaccgct acctgtacag
     6301 tatgcagatt ataccctatg gcaaagacga ctccttggcc aagacattaa gccagatagt
     6361 attattactc atcaacttga ctattggcgc aaaaacctag cggagctacc tgaacttgta
     6421 tcccttcctg gagatcgccc ccgatctgct gtcccttcct ttagaggtgc tcttattccc
     6481 tttcggttga gccctgaact ccatcatggg gcgatcaatc tggctcaaca acaaggaaca
     6541 agtctattca tggtgttgca tgctgttctt gctgtccttt taactcgtct gggtgcagga
     6601 accgatctgc ccattggaac ccctgtggct aatcgcacag atgatgcact tgaagatttg
     6661 gttgggttct ttgttaactt gctcgttcta cgaacagata cctctggcga tccaagtttc
     6721 tccgatctct tagcccgaat cagagaccta gatattgctg cttatgccca tcaagatatt
     6781 ccctttgagt tgttggtcga gaaacttcga cccgtgagat ccataactca tcaccccttc
     6841 tttgaaattt tgctagccct acagagtgca ccagagaatc agttaaagct gtctggggtt
     6901 aagataagtc acaaacaggt tcatttggga acctgtcgtt ttgatttggt gatgaatctt
     6961 gatgaacacc gacatcagga cgggacactc ctgggaattg atggcctggt tgagtatcgt
     7021 actgatttgt acgatcgtaa gacgattcag acttttatcg atcgcttctt gagactcttg
     7081 accggagcca ttgctgaccc tcaacagcgg attagtagac tcaacctctt gagtcctgaa
     7141 gaacaccatc aactcttgat cgaatggaat gatacggacc atagcatcag tccacgacct
     7201 tttccagacc tgtttgaagc ccaagtagcc caaactccta cagctaatgc acttgtattt
     7261 ggggctttgc atctgtccta tcaagaactc aatgctcgtg ctaaccaact agcccatcaa
     7321 ctgatctatc aaggcatagg tccaggccaa gtcatcgcga tcgatgttcc acgatcgccc
     7381 gaatgggtca ttgctgtttt agctgtactc aaagcaggtg cagcctactt acccctagac
     7441 ccctcttacc cagcctctcg cattatctat atgctggagg atgtccaacc ctgcctgtta
     7501 atcaccacaa ctaatagtct cattagtaat ccaaagctca atattccaaa actacaactc
     7561 gatagctttc cctgggaggc ttcccttaac gtcaccagtg aaaaacagga ttatggatta
     7621 caggctaata tagaggacaa tcggggcact cagccactgc atgtgtccga tccagcctat
     7681 ataatttaca cttcaggctc tacaggaaaa cccaaaggag ttgtggtaac ccatgctgga
     7741 atttcgagta tggtcgcaac acaaatcaag tactttgagg taactcctga gagtcgtatc
     7801 ctccagttct cttctttaag ttttgacggc gtagtttggg aactgtgcag tgccctgtta
     7861 actggtgcca ccttggtgat ggctccctca gaacgggtgc aaccaggtcc ggaactgatc
     7921 caattgatcg gagactatca cgttacccat gctgtcttgc caccagcagt attaatggtg
     7981 ctatcaccag ataatatacc ctccttgacc catctcattg tctcaggcga ggctgcctca
     8041 ggtgaattag taaaacggtg gtctgttggg cgctgcttga ttaatggtta tggtcccact
     8101 gaaactaccg tctgtgctac cttgagttct cccctatctg gtaatgggat accccccatt
     8161 ggcagagcgg ttatcaacgt tcaatgttat gtccttgatg atcaattgca acttcttccc
     8221 cctggagcga tcggtgaact ttacatatct ggccctggcc tagcccgtgg atatctgaac
     8281 cagcctcagc ttacggcaga gcgattcttg gcaaatccct ttagggacat cggaagccgt
     8341 atgtatcgga ctggagattt agttcgttgg cgaaaccacg gtgagcttga gtttgtaggc
     8401 agagctgata atcaggtcaa gattcggggt tttcgtgttg aattgggtga agtagaaact
     8461 gcccttacca attgtccccc agtgtcagat gccctcgcta tggttcgtga ggatcgaccg
     8521 ggcgaaaaat tcctagtggc ctatgtggtt ggtcaggatt ctatggatac tgatgctctg
     8581 cgtgcccagc tcgttaatga tttacctcca tacttgatcc ctggcgctat tgtcactttg
     8641 aagaaatttc ccctgacagt gaacggtaaa atagatcgta aggctctccc agttccaaag
     8701 ttcacttcta ttgctgaagg gcgtgttccc aaaactccta cccagattgg tttatgtact
     8761 ctgtttgcag aactgttggg tgttgatcaa gtcacgatcg acgatccgtt ttttgccctt
     8821 ggaggtcact cgttgctagc cacacaatta gtgagtcaga ttcggcagcg ttttgggata
     8881 agtttgccag tgcaaactgt attcgagcga cagacggtgg ctgacctggc aatagtagta
     8941 gatcgggaag cacctatagt ttctacttcc attgaccttg ctgctgaagt tgttcttaat
     9001 ccgcagattg ctccctacca gagtcgtcca gttgaactcg ataggaatac tcacccagcc
     9061 tcggtgttat taaccggagc aactggcttt ttgggggcat atttgcttta tgaacttctg
     9121 aagcagactg atgctaatgt attttgcttg gtgcgctcca accactctga agctgcctat
     9181 caacgcatcc attcgactct caaattttat caattatggt ctgaatcttg gagatcgcga
     9241 atcattccag tgtgtggcga tctctcccag ccaagtttag gcttatccgc tgaggaattc
     9301 agcaagctca cagaattaat tgatgctatc tatcacaatg gagcccaggt cagtgctatt
     9361 gaaccctata cataccttaa accaacaaat gtattgggga catcagagtt actggacttt
     9421 gctgcgcgat gccgcgtgaa gccattgcac tttgtttcaa cagctgcagt ggctgtaagt
     9481 tctaaaggta atcctgatat aatttatgag aattttagac ttggagcaga ttctgtatta
     9541 cccagtggat atgtctctag taaatgggtc gctgaagagt tagtgtgggt ggcatcagac
     9601 cgtggcctcc ccgttactgt ccaccgccca ggccgaatta gtggtgatac cactactggt
     9661 attgggaata ctgatgatac attctggcaa atagtcaggg caatagttgt tctaggggtt
     9721 gtcccagata ttgtttatca agatgatgcc gggatcgatt taatgccagt cgatcgcgtt
     9781 gcaagtgcaa ttgtccatct atcccgtcat aaacaatcca taagcaaggt gcatcacctc
     9841 acctgtccta caatagtcaa gctagatgta gtgtttaatg aactctctaa attgggctac
     9901 cagttaacca cggtatccta ctctgaatgg gttaagcaat tagaacagta cgtcgatcaa
     9961 gccccagggg ggcactccct agcatcagct accgtcctta gtcgtacatt acccaagctc
    10021 atagaactca gtcaaatctg cttcgaccaa agcaacacct taacgggttt agctgaagca
    10081 ccatttaagt ttccttgtat tgatcgtcat cttgtccgtg gatacctcac ttatttcatc
    10141 aactctaaat tcttccctca aataacttat acaggaaagt aaacatgaca aatccttttg
    10201 cagacccttc aagggactac tgggtactat gcaatgccga aggtcaatat tccctatggc
    10261 ccacttccct tgaaattcct gaaggctggc aaaccgcttt cggccccgag agttggcaaa
    10321 attgccttga caacgttgag aaaaactgga ctgacatgcg ccccctcagt ctgttaggtc
    10381 aacggaagtg tcctgtgcct tacccctttc gagaatatgt tgcccttaac atggatccaa
    10441 tctacgccag tctgcaacaa cgggatgaaa tgctacgaat tagtgttccc tatggggatg
    10501 atgcctggtt agcctccagt tacaaacatg tcaagtgtgt tatacaagat acacgtttta
    10561 gccgagaaac aactaagtat gatgaggctc gcttaacacc aataccgatc cgcacgagtg
    10621 tattggggat ggatcctcca gaccatacac gattacgtga ggctttagcc gcagctctca
    10681 ctcctagtca tgttgagcaa atgaagcctt ggataaccag catgacagaa caactgatcg
    10741 atgactttgt ggcccaaggt ccccctgccg atctagtcga gcaatttgct ttgccattta
    10801 ctggacacat aacttgcgaa ctcatgggaa ttccgctaga agatcgtccc caattcaaag
    10861 catggtgtga tggattttcc tccacttcgt ctctcaccaa agaggaagta gaagttcgta
    10921 tgcaggcaat gtatacctat attactgagc ttgtggggcg acgacgggaa tctccaagtg
    10981 atgacattat tagtaaatta ctgcaacctg aggataagcg cctggagcta tcagaaattg
    11041 aactgattga cctagccacg atcttattac ttgcaggata tgactcaaca gctatggaac
    11101 ttgcaaatgc gatttttgta cttttaaccc acccagaaca gacccaactc atccgagaac
    11161 aacccaagct gatgccccaa gctgtgcaag aattgctccg ctatattccc attgacgccc
    11221 atgttacttt tgctcgctat gccactgagg acgttcaggt tggtaatacg cttgttcgca
    11281 ctggtgatgc aattttggcg tctttcccct ctgccaatca cgatcctgca atatttgaag
    11341 atcctcacac attcaatatc atgcgacctc gcaaaccaaa ctttggctta ggaactggta
    11401 tacacagttg tgctggtaag ctcctggctg ttgtggagtt ggagattgca ctatctgtct
    11461 tgattagacg tctgcctact ttacgtttag ctattccagc tgaagaagtg ccatggcaac
    11521 caggctctct gttgcgcagt acttcaaagt tacctgctga gtggtaacta aaaaagtagt
    11581 aatctccatg gctttaggcc ggaaaggatg tcatttcagt tatcagttat cagtacctcc
    11641 tgctgaagca ggaggcttga gacccaaatt tttcggtcaa tgattccatt ttatctgtcc
    11701 tttatctctg taaattggag tgttttctta tgaattcaaa gatcgctgtt tctgaatacg
    11761 ccagtgatag ttttggtaag gctgatactc gggcctatga tgacctgcca attttcgctt
    11821 caaattatta ctcacgagaa gcgagttata ttgatattgc ctgtgacaaa ctacatcgag
    11881 cgtgtgatgg attggccttc ccagcagagc gtagggatac catagttgcc ttccttcgta
    11941 aactctgtac cccatggggt aacgctttag ctagtgctcc gcagcatttt tctaatgtat
    12001 ctgttgaggg aatgcccttt gaactatccc tggcctggag caatggtcga ggtcatgaat
    12061 tacggatgtc ttttgaagtc ctccatagcc cccatagctt gagtaataat cttgaagctg
    12121 cccgtcgatt tgtgcgagag ctgcccagta ttcctgaatt ggctccggat atctccattg
    12181 agaactttct tctaattgaa gatttagtga ctgcttccga gccaacagat tttattactc
    12241 ccatgggtca gggtattgct tggttatctg acagaccaaa tcctgtgatg aaaacctacc
    12301 ttaatctcaa tattgctggt tttgaatctg ggcctgagcg aactaaggaa gccatgacta
    12361 ggttaggtgc aggttctgcc tggcaatcac tttgttccta tctcactagc ctgggagtgt
    12421 cggttgttcc cctcttccta gctctcgatc tggctcattc agaccatccc agactcaaga
    12481 tttatttacc ccatacaggg gttgatgctg ggatgattga taaacaggca gaaattgctc
    12541 aaacccatgt taacgggaaa tttaaagagg cattactaga gattactggg catacaacac
    12601 cagactggcg aaaagtccct gttacttgct ataccctcgt tccagggcaa gatcgccccg
    12661 tggcagcaac cctttatgtt ccgctcaatc ccaatattga aaatgatgca gtcgcccaag
    12721 aacgggtctg tgccttctcc caatctcaag gagttgaccc ctcaccctac gagtcattac
    12781 tcaaggcaat ctccgataag ccactatctc aattatcaac ccacaatttc gtagcctatc
    12841 gaccaggcaa agatccgcgc ttttcagttt atcttgcacc aggagtctat aaacggtcat
    12901 aaactctagg aaaaaaacat ggggattgac aaggatagtt agcactgata acacttgcac
    12961 tggaaatact ttagtaggag caagggtgta taaggacaca ggttcaaacc gataaattgc
    13021 aatatagcaa tcctctaatc agttgtaata ttttggtggt agttaggagt cagaattcat
    13081 aattttcaag cttttcagct caaattaact attataaaaa ttgtcacgac caatgcgcgg
    13141 attgctatat acatctccag aaaagaggaa gtagggagca gggagcaggg agtagggaga
    13201 aataattgat gatttctctg ggataattga ttttattttt tattattgga gatgtctaat
    13261 gggaaaacta caaggtaagg ttgctattat tacgggtggt tcgcgaggca ttggacgagc
    13321 aatagcagag cgacttgctc aggatggagc gacaataatg ctaacctact tacggaacaa
    13381 agcgcttgct gaagcggtag ttgctcagat tgaaacacag gggggacagg ctagagcaat
    13441 ggcggttgac ctagctcaac ctgctgatat tgaacgactc ttcgagatga ccgaggcgac
    13501 atggcaacga cttgatattc ttgttaacag tgcggctgaa ctacagactg gcagcattga
    13561 atcgttttca attcatgatt ggcagcgggt atttgcagtc aattctacag ctccctttct
    13621 cacaatccag caagcggctc gtcgtttaag tgcccatggc cgtattgtta atgtctctac
    13681 aatcaataca gtcttggcag aacctggcat tgcggcctat gctgcaagta aaggctctct
    13741 agaacaattg actcgtgtcg ctgcatggga attggctgat cgaggaatta cggtcaattc
    13801 tgtatcaccg ggacccacag atacagactt gcttcggaca ggtaatccac ctgaagtttt
    13861 ggagcaagcc attgcgatga ctcctttagg gcgtcttggg caacctaaag atattgccga
    13921 cgtagtggcc tttcttgttg ggaatgacgg gcgttggata acaggacaaa atttgagagt
    13981 tacaggaggg ttgatctaag cgatctttag atggcgtaga atctaatatt ttgcgtaagt
    14041 cctgatacag tcattataat accgttacgc ttaaacataa gttgattctt gaatgctact
    14101 taaatataag tacaagctca agtctatatt tgagcttatt tttggctgct attttttgta
    14161 agtcccacta acttctaatt gatgacacac tctagcatag cgatcgctat cgacctagat
    14221 catacagtac caattttgtc aattttttaa ttggggctgg ctgaataaat ctaaaagtct
    14281 ttacagataa aggttatatc atgtccggat aatcagtgat caaaaaacct tttctcttct
    14341 aaccttttct ttccttctgc ctccagcata agtgcctttt gctttacctc ttccaaagtg
    14401 taagtattca accggacatg atattatagc ctttttaaat cccgaaaaag tgcagttttt
    14461 cctgtctata ctaacaaaaa gttaggattt taggcagacc aaggatagaa aaataaagga
    14521 acaattattc ctcctacttt ctctttcttc ccaccctccc cacacttccc acactttgct
    14581 tttttcagca aaccctaatt gatgacacgc cctagcattt tgcgcaaata atatcaaaaa
    14641 atgtttaagc agtgattaga gcatgaagat acaaatagag ctgctcatta ctacttgtga
    14701 agagaatatc gttttatatc gcttacacag gtaaattgtc aactaagtca aaactccaca
    14761 aaaaactaaa gagactgttg atatttcacc aaaagttcag aaatataatc ataaccatcc
    14821 actccaataa ctggcaaaat ttctgaccgt ttctgattta aaatctcatt aaactcttct
    14881 cccaattgac ctttcaatac aaccattaac ccagcagttt gtcgccattc attagcacca
    14941 atttgctcta acaaatacat acccaaacta ccagcaaaaa tagcttgttc caaattttgt
    15001 aaactatagt aagcttgagc aagataagcc aaattcaaac cttgtaaata taaatcccca
    15061 gaatattgag cagcttgcca accacccact aaatataaca aagcctcctc aggtttttct
    15121 aacaccataa atgcgattcc caaactacta aaacaaagag acttactctg accatcaccc
    15181 aaactttccg ataattttaa accctgttgt agataattaa tcgcattttc ataaatctca
    15241 gtttccatca cttcttgttg tctagcttgg aaaacttcac taaaacctaa attagccaca
    15301 gcattagctt cccctttttt atcccctatt tgtcgcgaaa acatcaacgc cctttgacta
    15361 taattaattg cctcactata atcttgcatc gccacacaag tccgactcaa atgattaaga
    15421 ttagcaattt cacagaattt atcctccgtc tcttgggcaa tttctaaagc ttgtttatga
    15481 aattccatcg cccttaaata ttcacccaaa gtacgctgag agtaacccaa taaagttaaa
    15541 attcttgcct ttgcttgagt acctttaact atttgcaaag gtgcatctaa ataactcaaa
    15601 gcattctgta aatattctcc agaaaaagaa gcaaaaattc caccatagag cggaaaatat
    15661 tcctgttgag aaaaggcacg aaaaatttgc aatgctacct gaaaacaaga attagttaaa
    15721 cgaggtctag cttgaaaacc attagctaac tgacaccaaa tagtagcaaa agttaaaaaa
    15781 gtagaaatag ataattttgc tcctacttta gcatcataaa ttaacttatc aaaccattct
    15841 actaatcccc tttgtaaaca ttgtaaaatt aatgccaatt caactaaatt actagcttca
    15901 atactcgcct tactcgcaaa ttctacaatc gacttttcca gggcaatagt attgaataaa
    15961 ccttctggaa aagaactatt tacctgtttt gcccataata tccacggtcc tcgttgttcg
    16021 ggagtaccac caaatcctaa ttgaccccta ctttggtcat agatccaact taccaaataa
    16081 ggttgcagtc gttgccaagc ttccagacct ttagtaatac cagtcgcaaa ctgttgcaag
    16141 agctttttct aactcagagt cagcagtttg gagtttttgt ccgtctagac tttgggctag
    16201 tttttgtagt tgattgagag ttaggggttg tttttggtta gggtcaatag cattgaataa
    16261 agtagtcagg cgatcgctag attcagcatt aataatttct tgtacagacg aagcgatcgc
    16321 ttcttgagtc tgatttagtt tttcccaccg ttcccattct ccttgaatag tttttaatgc
    16381 tcgcaaacga cgattagctt ttgcttgttt taactcatca gtttctgtat ctacttggtt
    16441 ttggatagtt tgcagacgtt catcaaaaca acgttcaaaa atttcgcctg taccactgct
    16501 aatttctttt accagcattt gatatacttg ttccttagaa cgaatttgac ctttgagagt
    16561 aatttccaaa atgtggtcaa ttaaattgag atagcgttcc tgccaagaaa tagattctgt
    16621 cattttaaaa tcgttttaat tacttatctt ttcgtttata agtttaattc ctacccactt
    16681 cacctatagt ttctacaagc ttgttggggt ttgactccat ccacttttcc tttccttaat
    16741 ttattcggtt cttccttctt ttttcttcct tcttccttct taaatacaat cacaataccg
    16801 attaagttaa tttatacatt tatcactaca aacatttgtt caaacatatc attaatcata
    16861 tcttccatat catctctatt tacagaatta ggacctctaa caaactcttt tagtgtaatt
    16921 ttccggtctt taaaatcttt aacaaaatta tgcaatactt gcaaagaatt tagatcaact
    16981 tctgcttctg caaccaaatt
//
