BGC0000412 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000412 (Pseudomonas aeruginosa PAO1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	15,023

BGC0000412 - Region 1 - NRPS

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Location: 1 - 15,023 nt. (total: 15,023 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 15,024
Label		BGC0000412

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000412.1	0.83	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0000465.1	0.32	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001843.1	0.28	NRP	tridecaptin M	Paenibacillus sp. M-152
BGC0000324.1	0.22	NRP	coelibactin	Streptomyces coelicolor A3(2)
BGC0001641.1	0.22	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000347.1	0.22	NRP	equibactin	Streptococcus equi subsp. equi
BGC0000396.1	0.21	NRP	nodularin	Nostoc sp. 73.1
BGC0001844.1	0.21	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.21	NRP	sevadicin	Paenibacillus larvae
BGC0000463.1	0.21	NRP	xantholysin A, xantholysin B, xantholysin C	Pseudomonas putida

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000412.1	0.94	NRP	pyochelin	Pseudomonas aeruginosa PAO1
BGC0000465.1	0.65	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001843.1	0.62	NRP	tridecaptin M	Paenibacillus sp. M-152
BGC0000324.1	0.55	NRP	coelibactin	Streptomyces coelicolor A3(2)
BGC0001641.1	0.55	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000347.1	0.55	NRP	equibactin	Streptococcus equi subsp. equi
BGC0000396.1	0.54	NRP	nodularin	Nostoc sp. 73.1
BGC0001844.1	0.53	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0000426.1	0.53	NRP	sevadicin	Paenibacillus larvae
BGC0000463.1	0.53	NRP	xantholysin A, xantholysin B, xantholysin C	Pseudomonas putida

Similar known gene clusters

No matches found.

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 15023:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (cys) + (NMe-cys)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

pchE

Search NORINE for peptide: strict or relaxed

AMP-binding (562..950): cys

NRPSPredictor2: cys

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLFNLSLIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)

pchF

Search NORINE for peptide: strict or relaxed

AMP-binding (519..915): cys

NRPSPredictor2: cys

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: cys
Small clusters prediction:: cys
Single AA prediction:: cys

Stachelhaus prediction details:

Stachelhaus sequence:: DLYNLSPIWK
Nearest Stachelhaus code:: cys
Stachelhaus code match:: 100% (strong)