BGC0000421: safracin A biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 1 - 17,974 nt. (total: 17,974 nt).
This entry is originally from NCBI GenBank AY061859.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000421
Short description safracin A biosynthetic gene cluster from Pseudomonas fluorescens
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AY061859.1
Compounds
  • safracin A
  • safracin B
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
safracin A
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C28H36N4O6
Chemical database entries
PubCHEM
safracin B
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C28H36N4O7
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAL33754.1
  • sfcJ
150 - 1679 (-) putative monooxygenase/hydroxylase
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  • AAL33755.1
  • sfcI
1669 - 2331 (-) putative methyltransferase
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  • AAL33756.1
  • sfcA
2870 - 5884 (+) putative non-ribosomal peptide synthetase
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  • AAL33757.1
  • sfcB
5898 - 9089 (+) putative non-ribosomal peptide synthetase
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  • AAL33758.1
  • sfcC
9093 - 13391 (+) putative non-ribosomal peptide synthetase
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  • AAL33759.1
  • sfcD
13420 - 14472 (+) hypothetical protein
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  • AAL33760.1
  • sfcE
14537 - 14722 (+) hypothetical protein
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  • AAL33761.1
  • sfcF
14780 - 15847 (+) putative methyltransferase
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  • AAL33762.1
  • sfcG
15933 - 16976 (+) putative methyltransferase
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  • AAL33763.1
  • sfcH
17062 - 17604 (+) conserved hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
sfcA
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
  • Homology
sfcB
Module ?
Specificity: glycine / 3-hydroxy-4-methoxyphenylalanine
Evidence for specificity:
  • Structure-based inference
  • Homology
sfcC
Module ?
Specificity: 3-hydroxy-O-methyltyrosine
Evidence for specificity:
  • Structure-based inference
  • Homology
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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