BGC0000432: streptothricin biosynthetic gene cluster from Streptomyces rochei
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 34,051 nt. (total: 34,051 nt).
This entry is originally from NCBI GenBank AB684619.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000432
Short description streptothricin biosynthetic gene cluster from Streptomyces rochei
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: AB684619.1
Compounds
  • streptothricin
Species Streptomyces rochei [taxonomy]
References
Chemical products information
streptothricin
Copy SMILES
C49H94N18O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAL15714.1
 1564 - 2133 (+) streptothricin acetyltransferase
copy AA seq
copy Nt seq
  • BAL15715.1
 2109 - 2888 (-) hypothetical protein
copy AA seq
copy Nt seq
  • BAL15716.1
 2878 - 3708 (-) hydrolase
copy AA seq
copy Nt seq
  • BAL15717.1
 3705 - 4811 (-) macrolide phosphotransferase
copy AA seq
copy Nt seq
  • BAL15718.1
 4808 - 6325 (-) NRPS
copy AA seq
copy Nt seq
  • BAL15719.1
 6327 - 8075 (+) peptidase
copy AA seq
copy Nt seq
  • BAL15720.1
 8040 - 9119 (-) glycosyl transferase
copy AA seq
copy Nt seq
  • BAL15721.1
 9332 - 10564 (-) carbamoyl-phosphate synthetase
copy AA seq
copy Nt seq
  • BAL15722.1
 10557 - 11261 (-) hypothetical protein
copy AA seq
copy Nt seq
  • BAL15723.1
 11258 - 13288 (-) oxidoreductase
copy AA seq
copy Nt seq
  • BAL15724.1
 13380 - 14123 (-) acyltransferase
copy AA seq
copy Nt seq
  • BAL15725.1
 14132 - 15166 (-) L-arginine beta-hydroxylase
copy AA seq
copy Nt seq
  • BAL15726.1
 15476 - 17464 (-) NRPS
copy AA seq
copy Nt seq
  • BAL15727.1
 17461 - 18621 (-) aminotransferase
copy AA seq
copy Nt seq
  • BAL15728.1
 18641 - 20065 (-) L-lysine 2,3-aminotransferase
copy AA seq
copy Nt seq
  • BAL15729.1
 20460 - 21437 (+) regulatory protein
copy AA seq
copy Nt seq
  • BAL15730.1
 21508 - 23241 (+) carbamoyl transferase
copy AA seq
copy Nt seq
  • BAL15731.1
 23238 - 25061 (+) NRPS
copy AA seq
copy Nt seq
  • BAL15732.1
 25099 - 26778 (+) NRPS
copy AA seq
copy Nt seq
  • BAL15733.1
 26775 - 28469 (+) ABC transporter
copy AA seq
copy Nt seq
  • BAL15734.1
 28466 - 30400 (+) ABC transporter
copy AA seq
copy Nt seq
  • BAL15735.1
 30504 - 31232 (+) Tyr/Ser phosphatase
copy AA seq
copy Nt seq
  • BAL15736.1
 31495 - 31908 (+) transposase
copy AA seq
copy Nt seq
  • BAL15737.1
 32522 - 32878 (+) transposase
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
BAL15718.1
Module ?
Specificity: beta-lysine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
  • Sequence-based prediction
BAL15732.1
Module ?
Specificity: beta-lysine
Evidence for specificity:
  • ATP-PPi exchange assay
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.