LOCUS       BGC0000469             39920 bp    DNA     linear   BCT 22-JAN-2019
DEFINITION  Streptomyces sp. BC16019 hypothetical protein genes, complete cds;
            bottromycin biosynthetic gene cluster, complete sequence; and
            hypothetical protein genes, complete cds.
ACCESSION   BGC0000469
VERSION     BGC0000469
KEYWORDS    .
SOURCE      Streptomyces sp. BC16019
  ORGANISM  Streptomyces sp. BC16019
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:36:59
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..39920
                     /db_xref="taxon:1109705"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. BC16019"
                     /strain="BC16019"
     subregion       1..39920
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000469"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..39920
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="bottromycin"
                     /region_number="1"
                     /rules="botH"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             complement(14..1204)
                     /codon_start=1
                     /note="Orf20"
                     /product="hypothetical protein"
                     /protein_id="AFV25464.1"
                     /transl_table=11
                     /translation="MLLFVAVVYVLAKWASHEGAGAWADYVAAAAEAGMVGALADWFAV
                     TALFRHPLGLPIPHTAIIPTKKDQLGVTLGEFVGENFLSQDVVRQRLRAVGIGSRLGAW
                     LAEPQNVDRVTAELATALRGALTVLRDSDVQAVVGEAITRRAGAQEVAPGLGKLLERVV
                     ADGGHKRAVDLVCARAQHWLILNETQVMDAIEGGAPGWTPRFVDRRIGERVYKELLRFV
                     TEMSDSPAHPARGALDRFLTDFATDLQSDTDTRTRVERLKGEVLGRGEVQDLIASAWTA
                     VRSMIVAAAEDERSELRLRVRTSLLSLGTRMATEPMAQAKVDKWLEGAAVHVVTTYRKE
                     ITSLITETVAGWDAEHTTRKIEANIGRDLQFIRINGTVVGSLAGLLIYTVSRALGA"
     CDS             1309..2976
                     /codon_start=1
                     /note="Orf19"
                     /product="hypothetical protein"
                     /protein_id="AFV25465.1"
                     /transl_table=11
                     /translation="MPLPPPLPLSYGPFTPPVPVPRTHCPVLRRFSSSARQFFGSSARQ
                     FFDPRLFACLVTYSIDLLRPTPGTEQEFPASVRAGEPMGVLPSRPRPMPHHGVITSEPR
                     GSTARGVTHRMTRQHGYALLAAMAALVVAISAAIYIGVGIDDGSRRQETFARAPRNSAA
                     PASTGVWVGAWATSPSGSEPGTETNGFAGRSVRNVVHTTAAGTSARVTLSNLYGQQPLT
                     ITHASLAVAATTNTAAAAADTMRRLTFAGNPTVVIAAGQQVVSDVVRVAIPYDSDVLIT
                     TYSPTPSGPATYHAHARQISYTAEGDRAADVTGEPYTTQSLHWRYVTALDVLSKESEGT
                     VVVLGDSLTDGVTSTVGENRRWTDVLAGRLRAAAGSSDTPRYSVVNEGISGNRVLTDGN
                     GRPAENPSGLNRFQRDVLGRTGVKAVVIDLGVNDILRNPGRADPDAVTAGLRQLVDRAH
                     ARGLRVVGTTLMPFHGHRGYSDQRESVRRAINDRIRSGEVFDTYVDFDQALRDPYDPRR
                     LRSDYDSGDHLHPSDKGYERMAEVFDLEKLKGAAPAEL"
     CDS             complement(3064..3918)
                     /codon_start=1
                     /note="Orf18"
                     /product="hypothetical protein"
                     /protein_id="AFV25466.1"
                     /transl_table=11
                     /translation="MIRMTDDLPDLPAAMDLRASDADRERVSEQLRDALAEGRLDMEEF
                     EERLDATYKARTYGELAPITRDLPGAGTVAPPAVVPPSSISLVKRPAEGASWPERIVGG
                     EGSSTWGVAVMSGFERKGRWTVPKRFDCFAFMGGGELDLRDAYFAEREVTINCVAIMGG
                     ISVVVPPGVEVVVRGIGIMGGFDHSADYEPGEPGAPRVVVTGFAFMGGVEVERKVPKAE
                     RQREKEARRRERLERRQARRELHASRRDHMHDLHDAHRDAMEQARDAMRSERERERRRR
                     GER"
     CDS             complement(4067..4969)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 174.8; E-value:
                     3.8e-53)"
                     /gene_kind="transport"
                     /note="Orf17"
                     /product="hypothetical protein"
                     /protein_id="AFV25467.1"
                     /transl_table=11
                     /translation="MRAVDSLSFTVARGEMVGYIGPNGAGKSTTIKMLTGILTPSGGRL
                     RVAGIDPSRERTRLARRIGVVFGQRTTLWWDLPLIDSYRLMHRMYRIPDARYRENLDRC
                     VELLELGALLDVPVRQLSLGQRMRGDIAAALLHDPEVLYLDEPTIGLDVISKAKVREFL
                     KELNTEQGTTVLLTTHDLQDIEQLCRRVMVIDHGRLMYDGPLTGLHEVGESERTLVVDL
                     ERELPPIEAAPARVVRVEGPRQWLAFPASESAAPLVARIASEYPLVDLSVREPDIEAVI
                     AQMYAQQAERVGETGQAVP"
     CDS             complement(5074..5955)
                     /codon_start=1
                     /note="Orf16"
                     /product="hypothetical protein"
                     /protein_id="AFV25468.1"
                     /transl_table=11
                     /translation="MADLDDRTVVRIKEENPFGEYGVYSRVRDGLRAYRMIAAMWIRST
                     MAYRASFAMTTFGNFAATSFDFVAILLMFSQVDELGGFSLPEIALLYGTSAVSFGLADL
                     MIGSMDRLGRRVRDGTLDTLLVRPVPVLAQVAADKFALRRLGRITQGLFVLGYALTTLD
                     IAWTPAKVLMIPLMVCSGGLIFAAVFVGGAAFQFVAQDASEVQNAFTYGGATLLQYPPA
                     LFAKDLLRGVTFVLPLAFVNWVPGLYVLGRPYPLDLPTWLAFAPPLVGVACCALAGVAW
                     RAGLRSYRSTGS"
     CDS             complement(5948..6682)
                     /codon_start=1
                     /note="Orf15"
                     /product="hypothetical protein"
                     /protein_id="AFV25469.1"
                     /transl_table=11
                     /translation="MATAAGVFTNTVFGFILAYTYLALWHEKPHLGGYDQAQALTYVWV
                     GQAMFAVMVLGSVGFEEELIERIRTGDIAVDLYRPVDLQLWWLAADMGRALFQLLGRGV
                     VPMVCGALFFDLALPSGPLPWLACLVAVALGALVSFAIRYIVALWAFWLLDGAGAMQIT
                     WLTGVFFSGMLLPLNVFPGALGDLARILPWSALLQAPADVLLGEADPLGTYAFQLAWAA
                     VLLAVGRLIQSAATRKVVVQGG"
     misc_feature    complement(6329..6331)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             8518..10941
                     /codon_start=1
                     /note="Orf14"
                     /product="hypothetical protein"
                     /protein_id="AFV25470.1"
                     /transl_table=11
                     /translation="MPDTPTQALGVIPAGKATAPAAVPDITPDPAGAGGKAKKPKRPKR
                     TGFRRLIPTWRFVLSAFVVGLMLIIGAFVLGYNMVHIPKPQDAATKQSNVFLYADGTQI
                     ARDGEVNRENVPLTKVSKEAQRAVLAAEDRDFYSEPAIDLKAMARAAWNTATGKGKQSG
                     STITQQYVKNYYLAQDQTVTRKVKEFFIAIKLDREVTKDEILEGYLNTSFFGRNAYGIQ
                     AAAQAYYGVDADELTAEQGAYLAALVNAPSMYDVVAHPENKDAAVARWNYVLDGMVKEG
                     WLKESERTGMKFPMPKQATTSSAFSGQRGYLVEAVKSYLINNKIIDEEALENGGGYRIT
                     TTIQPKMQNAFIKAVDDQLMDELDKKNRKVDNYVRAGGVSIDPKTGKVIAMYGGIDYTK
                     QYVNNATRRDFQVGSTFKPFVFTSAVENASNNQSGQAITPNTIYDGTNKRPVVGWPGET
                     YAPENEDYVNYGNITVRQATQSSVNSVYAQMAVDVGPEKVEKTAIDLGLPKDTPDMNPY
                     PSIALGTATASVLDMTEAYATLANHGKHGTYTMVEKISKDGEAVKLPSTESTQAVSRKA
                     ADTTTAVLQSVVESGTATAAQASGHPVAGKTGTAEEDQAAWFAGYTPDLATVVSVMAQD
                     PKTGAHKSLYGAMGLPRINGGGAPTEIWAQFTKAALKGKKVKDFDLDLQIGADVVITPP
                     STPADEPGATGEEQDGGATGEEETGRPDDGTDGGTTTGGTPATDGGTTSTGGTATDGGT
                     TSTGGSTTTDGGTTSTGGPTTDGGTTTDGGTTTDGGTTDGGTTTGGGATEGTFP"
     CDS             complement(11018..11359)
                     /codon_start=1
                     /note="Orf13"
                     /product="hypothetical protein"
                     /protein_id="AFV25471.1"
                     /transl_table=11
                     /translation="MSEKTQHDKLPIRMLHDRVLVRQDTAEGERRSGGGILIPATAAVG
                     RRLAWAEVVAVGQNVRTVEPGDRVLYDPEDRAEVEVRGVAYVLMRERDLHAVAADRFEG
                     SEDSTGLYL"
     CDS             11793..12338
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196:alkyl hydroperoxide reductase/ Thiol specific
                     (Score: 155.9; E-value: 1e-47)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf12"
                     /product="hypothetical protein"
                     /protein_id="AFV25472.1"
                     /transl_table=11
                     /translation="MKSLGCGQSVSSPRRRSARARHYAGPMSERLQPGDVAPAFTLPDA
                     DGNEVSLSDHKGRKVIVYFYPAALTPGCTKQACDFTDNLELLADAGYDVLGISPDKPEK
                     LAKFREKESLKVTLLGDPDKTVLDAYGAFGEKKNYGKTYMGVIRSTIVVDEQGKVERAL
                     YNVRATGHVAKIIKDLGI"
     CDS             12477..12749
                     /codon_start=1
                     /note="Orf11"
                     /product="hypothetical protein"
                     /protein_id="AFV25473.1"
                     /transl_table=11
                     /translation="MGASAYPKERLEEAARGARTLSEALGRLGVDPKSSTRRYLLERMK
                     KLGVDVPRRRPSGARHGVPERRKACSSSSRPARLDASQAIGSSGR"
     CDS             12847..13653
                     /codon_start=1
                     /note="Orf10"
                     /product="hypothetical protein"
                     /protein_id="AFV25474.1"
                     /transl_table=11
                     /translation="MARQPHREPAVPVSQLPLDDGHLPGARQRSCLMSSGAQYTRERLV
                     EAAAQCSDIDEVITFFGTRPYGNLPRHLYKRFDHFGIDISHFNRWFRLPRPTAEQLRTA
                     VAESASIAGVLRTLGRPDTGRQRALLRRWIAEEDLTTEHFLGQAHQRGKPGTARAKHPD
                     EILIQHDGKRRTKTQLLRRALREVGVPEVCADCGTGPKWLGKPMTLEIDHINGDWSDDR
                     RENLRLLCPNCHAISSTWCRGGSKAASPGKVGRGQAPVRQGLSGNL"
     misc_feature    12913..12915
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(13747..14349)
                     /codon_start=1
                     /note="Orf9"
                     /product="hypothetical protein"
                     /protein_id="AFV25475.1"
                     /transl_table=11
                     /translation="MTRLILATRNAGKLTELKAILADAGLSYDLVGADAYPEIPDVKET
                     GVTFAENALLKAHALAQATGHPAIADDSGLCVDVLNGAPGIFSARWAGRHGDDKANLEL
                     LLAQLGDIADEHRGAHFTCAAALALPDGTERVVEGQLRGVLRHVPTGTNGFGYDPILQP
                     EGETRTCAELTAEEKNAISHRGQAFRGLVPVLRELVG"
     CDS             complement(14941..15678)
                     /codon_start=1
                     /note="Orf8"
                     /product="hypothetical protein"
                     /protein_id="AFV25476.1"
                     /transl_table=11
                     /translation="MSRIDGRTPEQLRPITIERGWSKHAEGSVLVSFGDTKVFCTASVT
                     EGVPRWRKGSGEGWVTAEYSMLPRATNTRGDRESVRGRIGGRTHEISRLIGRSLRAVID
                     YKALGENTIVLDCDVLQADGGTRTAAITGAYVALADAVSWAQGKKLIKAGRQPLTGTVS
                     AVSVGIVGGVPLLDLCYEEDVKADTDMNVVCTGDGRFVEVQGTAEAEPFAREELNSLLD
                     LAVSGCTELALLQRKALDTVLER"
     CDS             complement(15757..15990)
                     /codon_start=1
                     /note="Orf7"
                     /product="hypothetical protein"
                     /protein_id="AFV25477.1"
                     /transl_table=11
                     /translation="MASKAEKIVAGLGGLDNIEEVEGCITRLRTEVHDASLVDEAALKA
                     AGAHGVVKMGTAIQVVIGTDADPIAAEIEDMM"
     protocluster    16119..37000
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[26118:27000]"
                     /cutoff="20000"
                     /detection_rule="botH"
                     /neighbourhood="10000"
                     /product="bottromycin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      26119..27000
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="botH"
                     /neighbourhood="10000"
                     /product="bottromycin"
                     /protocluster_number="1"
     cand_cluster    16119..37000
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="botH"
                     /kind="single"
                     /product="bottromycin"
                     /protoclusters="1"
                     /tool="antismash"
     gene            complement(16255..17550)
                     /gene="botT"
     CDS             complement(16255..17550)
                     /codon_start=1
                     /gene="botT"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 185.5; E-value: 2.6e-56)"
                     /gene_kind="transport"
                     /product="BotT"
                     /protein_id="AFV25478.1"
                     /transl_table=11
                     /translation="MLPLYLISHGLSLLGNTVASIALPWLVLLRTGDATAVGLVAAASA
                     LPMLLSAVAGGVLIDRVGRRRLSIGADLASAACVAALPVVDGLLGLTVVWFVVLGVAGA
                     VFDVPGMTAREALAPDIAEATGIGMERLAGLRESIAGGVVILAPAAAGGLIMLVDPATV
                     LWLTAGCSALAALVTFALPKTIGAQPTATAQGDGAGLRGDLKRGLGVLRGDRVLTAVTL
                     VSAGSVAVLAPLQNLVLPVHLVGKDSPGGFGVVVSLLAVGGIAGAGLYAAIGTRWSRRT
                     VFVAAQLTSTIGIAGLALLPPVPVMWAAAVLAGAGAGPLPALFLVLVTERIPEEVRGRV
                     LGLQNAVSMTAVPLGTLVAGLTVDWIGLRQTGALLAIAWCVVTLAIVALPALRNLDAGR
                     AKSEPPAEDQPTPDGGSPIPGQGSETADTPTA"
     misc_feature    16255..33922
                     /note="bottromycin biosynthetic gene cluster; may include
                     additional flanking genes"
     gene            complement(18069..18908)
                     /gene="botOMT"
     CDS             complement(18069..18908)
                     /codon_start=1
                     /gene="botOMT"
                     /product="BotOMT"
                     /protein_id="AFV25479.1"
                     /transl_table=11
                     /translation="MKISLTGAAETLLAPLYARALDARSAHPLLGDHIAAELLDRIDYD
                     FDRLGMGEASAVGVALRARYFDRRVRAFLDAHPESTVVHLGCGLDSRFERLAPGPGVRW
                     FDLDQPDVIELRKQLYPARPGHETLATSVTEPDWPAQVPTDRPVLVVAEGLSMYLSADE
                     GPRMLRTLVAHFPQGELLFDTYSRFAVRSTRSLALFRKTGARLAWGVNDPRELERGIPG
                     LRLIETDSAYATAAGVDVSHLPRTLRRRMRIDTHILARLPVLRHIGHISRYAFGPPA"
     gene            19314..21239
                     /gene="botRMT1"
     CDS             19314..21239
                     /codon_start=1
                     /gene="botRMT1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 169.3; E-value: 2.1e-51)"
                     /gene_kind="biosynthetic"
                     /product="BotRMT1"
                     /protein_id="AFV25480.1"
                     /sec_met_domain="TIGR03975 (E-value: 1.9e-159, bitscore:
                     522.8, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 1.2e-40, bitscore: 128.8, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAAKNVSLVSMPWNSVIRPSIQVGILRSLAESEGWQVDARYSYL
                     DFYGLAQRMLGFSDEKWSEAYELVSEKLYHLSVGDWIFSCRRGDAERREAYFAQLRARR
                     VDDTSIELVDALREVADRHVERTAAELLESAPDVVGFTSMFSQNGPSLAVAERLRDLGY
                     GGVIVLGGSNCEGSMGRALLANYPAVDAIVDGPGEDAFVTLLRQAEAGGPLRTRGRLVT
                     RLPADDDAAPAAPLTAAAALDVPTPNYDGFFEQLHAAGLHGLESEITLPVEFSRGCWWG
                     AKTHCTFCGLNGATMAYRSKNPDTVADELRHLMDRYGVLDFFAVDNILDLKYLDTALPS
                     VEKLNTDHSLFFEVKANMEWADIRAVRRAGVRSVQPGIESLSTEGLRHLRKGATAYQNI
                     RFLLGCAEYGVRADWNILTGYPHETPDSLKAQLDVVASLTHLTPPHITLIRFDRFSPYV
                     EAPESYGLTLTSPLPGYQYAYPRLSPEDLWDIAYHFEGDFTDDPDNGPVRRRLAARVRL
                     WRAHHESARFSYRLGFDSVTLTDERPGLPPHTTTLRGEEARLFRAVVGGTRFRDLQGQE
                     WQGERWDQALETLRTWRRKRWVYIEGTKVIALAVREQPSAYRTPPPKGTPRRARTPVPL
                     TLTARP"
     gene            21336..21470
                     /gene="botA"
     CDS             21336..21470
                     /codon_start=1
                     /gene="botA"
                     /product="BotA"
                     /protein_id="AFV25481.1"
                     /transl_table=11
                     /translation="MGPVVVFDCMTADFLNDDPNNAELSALEMEELESWGAWDGEATS"
     gene            21534..22838
                     /gene="botC"
     CDS             21534..22838
                     /codon_start=1
                     /gene="botC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /product="BotC"
                     /protein_id="AFV25482.1"
                     /sec_met_domain="YcaO (E-value: 1.5e-11, bitscore: 35.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEATATECELREVVHRSYPSDRTVTVRCTVRPAEGTAQADGYGT
                     ATTEAVARAKALSEAVERLVACTPFATVARPPTTPAPGSGSGPVPPFPAAGVRTAPDGC
                     ASREYRPLSGDGPRRVPLYWSSPWVAGEELRAGTLSAAEARLSSTVGWAVAPTPEAALR
                     GALLELTELIDYGVFLHRRLAGPARPRSAGDETLVVPLGGAVRTPTVLAVAYGRGRLMP
                     ATGLGCGASRAEATDRALLELAQAETMWRSNPTAEPAERFFLRRFERWPLLTRCATLDF
                     ELSDLSGLDGLSGLDGLSRLDGLSRLDHPSDLNDPAGRPAPYDDGPHPASPLEELEAGG
                     ITVWADSGAVDISGPDIPRTRLCFAHVVSDPQPLLGLVRAGIPVFDTGEVRRTLDPSRR
                     DAHRDTPRGAPRDAARDRSADRGPAGRGRQGRRSA"
     gene            22951..24153
                     /gene="botCD"
     CDS             22951..24153
                     /codon_start=1
                     /gene="botCD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /product="BotCD"
                     /protein_id="AFV25483.1"
                     /sec_met_domain="YcaO (E-value: 1.7e-39, bitscore: 127.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTDAEGALCSRSSGKGLGHRSMASALFESAEHYHLDWRRDPRA
                     SEAEFLPGREIAGQDTARRSALLRRLGGIMPDAPVLTRTYRPVEETLTGRADHGPAGRP
                     HRHPVFLRDGGYRNWPHPDDDRSFQPLWHYTSSAGYAAGATVHEALVHAVNELIERDAW
                     SYQLARSYFGLPGEGPELRVVDHDTLPAELRELTGTVEEVREAPVLIVDITCDTGVPAY
                     VVCDARSREEVRLIGSGASPVRTYALQRALLEYLQVRTMFEHGPVDADTEAGQIATALA
                     RYPRHLAAARFDVGQLPHERRAFDADDGLPAAASPEQLLRHLVDRLRDLGVDVHHRVLT
                     PPGSVTVVDVVAPGLEMFDKARAGYPVLPTGRLGERLRPRKDHERGHGVDHGKDRGGAP
                     R"
     gene            24150..26132
                     /gene="botRMT2"
     CDS             24150..26132
                     /codon_start=1
                     /gene="botRMT2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 120.4; E-value: 1.4e-36)"
                     /gene_kind="biosynthetic"
                     /product="BotRMT2"
                     /protein_id="AFV25484.1"
                     /sec_met_domain="TIGR03975 (E-value: 7.6e-131, bitscore:
                     428.4, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 5.2e-37, bitscore: 117.1, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLALVAPPWNSLYRPSIQIATLAALEGTGDGDPITPVYAYLDWF
                     EYAVDALECDPAEFVTVYDTIGEELYGLGVGDWIFGGVLDAHGPGEEADVRDRYAAFLT
                     EHGVAEELVGRVLALRAVAPGFAAGLAGRLVATGAECFGFTTSFSQLMPALAVARAVKD
                     QAPERLVLLGGANCDRPMGQAVMRAYPFVDAVVQGEGEAAVAAVRAARGAGDLAAAPGL
                     VLRHEGGLRVSLPTVQPAESAPVPRYAEYFERLRALPHRELIAPHVALPFQMSRGCWWG
                     EKLQCTFCGENGSGMVYRSKPGEQLTKTLRRLTEEHGVFDTYAVDTILARNDNGLAELA
                     AAEVDITTFFEVKANLGPREVGEMRAAGVTMVQPGIESLSSGALKLLRKGATAFHNLRF
                     LVLCQELGIDAQWNLLSAMPDETAEMLQEQLRLIPFITHLAPPSTVSKVRVDRYSPYFE
                     KPEEFGIALDGPEPKYRFVHAGRTAAERAELAYSFDHVELAGRDDSAMAAEMLALRRRL
                     GARVGLWKKLHDQSRFSFRFGPNMTVLHDGRPHVGTGRHVLRGGDDQLFRCLVHGGRLH
                     QAVGQVAAMTGRPEDEVHARVREWARRGWVHLEGRRGLVLAVRDGMRDELGRAAELREA
                     AAESERAAAESGMAGAGSGRVGAGR"
     gene            26119..27000
                     /gene="botH"
     CDS             26119..27000
                     /codon_start=1
                     /gene="botH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     bottromycin: botH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic"
                     /product="BotH"
                     /protein_id="AFV25485.1"
                     /sec_met_domain="botH (E-value: 1.6e-159, bitscore: 520.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-10, bitscore:
                     33.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 7.1e-13, bitscore: 39.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDGNGTSRRDVFEVFSRDGTPIRGFSRPGPGETVVLVHGVAMDR
                     RIWAESGFLDALPDAHVLALDLRGRGESGRVGTAEGHALRRYVEDVRAVLDRFGRARYS
                     LFGTFFGGRIALQVAAVDTRVARAFSFCAHAEQVEIPEDAVEEEAVAVEGPGGHAYLRD
                     HFTGRGAPPWMVEACARVDPGELGAATRGLLHGSDRRTERGHPDQELVLITADGDADLA
                     PFHAGERRLGAHLWLVDAPTRIKAAGRLAEVGRRVAGVLAEGGHGTGDAPAEARTTGDA
                     PAEARASGTGVV"
     gene            27018..28415
                     /gene="botAH"
     CDS             27018..28415
                     /codon_start=1
                     /gene="botAH"
                     /product="BotAH"
                     /protein_id="AFV25486.1"
                     /transl_table=11
                     /translation="MWRRRRGLLPDGDPLVRALEELAERGRGHRLRAVGLVDPATGRPG
                     PPHDLTVTDGTVTAWTPTPPAADGRAAPYTSYAVPGLVDSHAHVSSAADLVGLLVHGVT
                     GFRQLWGEPAHLYAAGVHRARHAVLPRPWVTAGVVDGPGSRIPQGVTVVDGVRSVRQVI
                     EDALAFGFDGIKVYDDVARPAFEVLVREAERAGLPVVGHIPEAVPLDLAQRTLRSSEHL
                     YGIVPNVFRLPPERRWDALAAALRDHPAPGAVPGHFVCPTLVCWRARSGERRYTRPSRA
                     ALQAVDEGRRRSWQSAARDALRLDAAEAHRRGGLVDGLGRIARALADTGTRLLAGTDCG
                     NPFVLAGPSFHKELAELSRAGLDFGAVLRAATTHAYEAMGRRAGPVPGDPADLVLYRRP
                     PDGDVTALARPDAVLVDGVLLDGTDLDRLWALRLAASGLDPSGWARGTLDPPVTTGRPT
                     KETAHAG"
     gene            28405..29631
                     /gene="botCYP"
     CDS             28405..29631
                     /codon_start=1
                     /gene="botCYP"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 231.7; E-value: 2.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /product="BotCYP"
                     /protein_id="AFV25487.2"
                     /sec_met_domain="p450 (E-value: 2.5e-11, bitscore: 34.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQADREPDRTGREAKRPAEPDHPPQQATCPVDFDFFAAPQTYRDA
                     AAEHAGEHGAFYSDRGFWVLTTYDGIVDAFKDEGTFTVGRVSAAEGAEEERWIPLTVEG
                     REHTAWRQRLGAWFTPQRVRELTPSMRAGARRRIEGFLEKGEVSFNEDFARPYVLENLM
                     TAVGWPPDGFDLLIAINRAMIDSRSAPDPRAAAYGELGLPALERFAREHIARRRAEPAD
                     DLTTASFGWEIDGAEVTDDDRASLLCTLFLAGIDSTVNHLANAVQHLAHHEEDRRRFLA
                     GPEVRPPAVEEFLRANSCMYPGRQAATGGAGGVADRGDTVLLPLALANHDPEVFPEPGR
                     IDFDRTRNPHIAFGTGPHQCLGAAFARAQILVALEEWHALVPDYAPSPEQRTAEPPFLR
                     NSYDLRLVW"
     gene            29639..31684
                     /gene="botRMT3"
     CDS             29639..31684
                     /codon_start=1
                     /gene="botRMT3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Bottromycin_Methyltransferase_RRE"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 158.4; E-value: 4.1e-48)"
                     /gene_kind="biosynthetic"
                     /product="BotRMT3"
                     /protein_id="AFV25488.1"
                     /sec_met_domain="TIGR03975 (E-value: 1.6e-160, bitscore:
                     526.4, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="Bottromycin_Methyltransferase_RRE
                     (E-value: 6.7e-38, bitscore: 119.9, seeds: 12, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTTERTEATGPADVTGTTEPTLATTPTEPATPSVPTRPGRAAL
                     VSMPWNNVRRPSIQVGTLRSVARTEGWRVDSHYAYLSFYGLARTALGMRDAEWSQAYET
                     VSEGLYQLSVGDWIFACRDGGAAAREAYFRMLRTKGVDDATIELVDALREVADRHVERT
                     AAELLESAPDLIGFTSTFSQNGPTLAVAERLRDLGYGGVIVLGGSNCEGSMGRALLANY
                     PAVDAIVDGPGEDAFVALLRQVGAGDPPRSHGRLITRLPALADSAPAGISAGQSLEVPT
                     PDYDGFFEQLHTAGLHTLEPEITLPVEFSRGCWWGAKTHCTFCGLNGATMTYRSKNPDT
                     VADELRHLMDRYGVLDFFAVDNILDLKYLDTALPLVEKLNTDHSLFFEVKANMEWADIQ
                     AARRAGVRSVQPGIESLSTEGLRLLKKGATAFQNIRFLLGCAEFGVLPVWNILTGFPHE
                     TPESMLTQIDLLPSLTHLEPPDNDILAVHFDRFSPYVEHPQDYGLTLTHPLPGYQYAYP
                     RLSPGDLWDLAYHFEGDFTEDPRNTAVRERLATAVHHWRTEHHRARFTYRLGFDSVTLT
                     DHRPGLPAHTTVLRDEDARLFRAIIGGTRFRDLQNQEGRDGQPLEKLHTWQEKRWVYIE
                     GTKVIALPVREKPSAYRTPPRKGTPRRSRTTVPLTLTGPPPPRRPG"
     gene            31849..32403
                     /gene="botR"
     CDS             31849..32403
                     /codon_start=1
                     /gene="botR"
                     /product="BotR"
                     /protein_id="AFV25489.1"
                     /transl_table=11
                     /translation="MTTAPTEDQTRAEDLPPSCRDLIGILAQTDRRDAFAALALGATSV
                     AQVAERAGLRPAAAAVALQKLVDGRIAAYDADARTYRLIDDTFRLAVQAEVRISGRGGG
                     DGAGAYFRKGRLTSIPGKAEVRSRVLAVVADSFEAGVTYSEAKVNAICGQWFDDWVTLR
                     RALVDEDLLRRDESGTQYERV"
     gene            32408..33922
                     /gene="botP"
     CDS             32408..33922
                     /codon_start=1
                     /gene="botP"
                     /product="BotP"
                     /protein_id="AFV25490.1"
                     /transl_table=11
                     /translation="MTRVVAGDVGTDTPDKAGTADTAKAADTADTASRAADVVACGRHT
                     GAAVGAFSRRRGFVARPGQVVAEPSADGRAVVLNVGLGPAGSATAATFRAAAAASVRAV
                     GPARTLRLDLALADGSGVPAAERARAVAEGAVLGLYRYDEYRSARAASPLAEVIVATPE
                     RRAVAEGLAAAEATCLARDLVNCPAGTLTPPAFADRIRELAHTAGLDCAVYEGAGLTEL
                     GLTGLTAVGRGSAEPPRYVELTYDPPDADPALTVGLVGKGVTFDSGGLSLKPSGERHAM
                     KADMGGAAAVVAALTALPRLGLPLRVRGHLPLAENMPDGGALRVGDVVRHLDGTTTEIT
                     HTDNEGRVVLADVLVRASRPGPHRSDLVVDVATLTSAAVHALGTRTGALFTPDDRLAQT
                     VLAASERAGESFCRLPLLAHERRNLRSAVADRVNCSHRHGDTIQAALFLQDFVAAGVPW
                     AHLDIAAPAYNDEGPYAEVPYGGTGFAVRTLIETLRALSEGSPDVP"
     CDS             34053..35306
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145:Glucose-specific phosphotransferase enzyme IIA
                     (Score: 427.3; E-value: 1.2e-129)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf1"
                     /product="hypothetical protein"
                     /protein_id="AFV25491.1"
                     /transl_table=11
                     /translation="MSTATAPSAAPAKKWGSGLMQGLQKVGRSLQLPIAVLPAAGLLVR
                     LGQPDVFGAEGLGWDKVAAVFDKAGGAITGNLAMLFCIGVAIGFAKKADGSTALAALVG
                     FLVYSKVLEAFPVTEAEITKGADVAATYNNPGVLGGIVMGLLSAVLWQRYHRKKLPDWL
                     GFFNGRRLVPIIMAFVGVAVGVFFGLVWEPIGEVIGSFGEWMTGLGSAGAALFGAINRA
                     LIPIGMHQFVNTVAWFQLGEFKDASGVVSHGDLSRFLAGDPTAGMFMSGFFPIMMFGLP
                     AAALAIAHTARPERRKVVTGMMISLALTSFVTGVTEPIEFSFMFIAPLLYVIHALLTAL
                     SMAITWGLGVHAGFNFSAGFIDYALNWNLATKPWLIIPIGLVFGAIYYVVFRFAIIRFN
                     LPTPGREPDEEIEDLTKA"
     CDS             complement(35391..36143)
                     /codon_start=1
                     /note="Orf2"
                     /product="hypothetical protein"
                     /protein_id="AFV25492.1"
                     /transl_table=11
                     /translation="MKLTVVGCSGSFPSAESACSSYLVEADGFRLLLDMGNGALGELQR
                     HCGLYDLDAIFLSHLHADHCIDMCAYFVARYYRHDGGRCDPIPVYGPEGTEQRLTTAYA
                     DTPSASSMSEVFDFHTVKPSTFELGPFTIHTERVAHPVEAYGIRIEHGGRVLTYSGDTG
                     VTHTLDELARDSDLFLCEAAFTHGKENIPDLHLNGREAGETAARAGARRLVLTHIPPWT
                     DPQVNLVDAREVYDGPVELAVPRMSYEI"
     CDS             36454..36978
                     /codon_start=1
                     /note="Orf3"
                     /product="hypothetical protein"
                     /protein_id="AFV25493.1"
                     /transl_table=11
                     /translation="MRQGGRGAVCAGTVGAMDTSWWLALAAVVLLALLATVVDGWGRSR
                     RPSRRSERPGGRTRPPGRPGRARGPVPRPRPSEIWWASVPFEDGPGGKDRPCLVLAVRG
                     DRARVAKITSRYRDERAGVIPLPPGTVGDARGRPSFLETGELREVPVGDFRRKAGVVDP
                     VLWDQIRRLSN"
     CDS             complement(37209..38132)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 310.8; E-value:
                     1.4e-94)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orf4"
                     /product="hypothetical protein"
                     /protein_id="AFV25494.1"
                     /transl_table=11
                     /translation="MGNTPLVRLPRLSPSADVRIWAKLEDRNPTGSVKDRPALHMIEQA
                     EKDGRLTPGCTILEPTSGNTGISLAMAAKLKGYRMVCVMPENTSQERRELLGMWGAEII
                     PSPAAGGSNTAVRVAKELSAEHPDWVMLYQYGNPDNAGAHYATTGPEILADLPSITHFV
                     AGLGTTGTLMGVGRFLREQKPDVKIVAAEPRYDDLVYGLRNLDEGFVPELYDASVLTTR
                     FSVGSADAVTRTRELLQQEGIFAGVSTGAALHAAIGVGNKAVKSGEPADIVFVVADGGW
                     KYLSTGVYTAATTEEAIETLQGQLWA"
     CDS             complement(38207..38485)
                     /codon_start=1
                     /note="Orf5"
                     /product="hypothetical protein"
                     /protein_id="AFV25495.1"
                     /transl_table=11
                     /translation="MAIEVRIPTILRQYTDGQKAVEGAGATLAELFTDLESRHTGIQAR
                     IVDAGELRRFVNVYLNDEDVRFLDGINTKLTDGDNVTILPAVAGGMV"
     CDS             complement(38795..39901)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 325.4; E-value: 6.8e-99)"
                     /gene_kind="regulatory"
                     /note="Orf6"
                     /product="hypothetical protein"
                     /protein_id="AFV25496.1"
                     /transl_table=11
                     /translation="MRTHARARTQQPATETVLTRQTRRPHGRRPTLDDVARGSGVSKST
                     VSRVINGEDKVRAEVVERVREVIAELGYVPNSAARQLVTRRNNAIAVVASQPQNRLFID
                     PFFDLHLRGIRKELVAHGAQPVLLFLEEPEEYPRVGDFLGGGHVDGALLFSLRADDPLP
                     GMIERLGLPAVFGGRPLVREGEPVRDCVYVDADNRGGAREAVRHLVSLGRERIATITGP
                     CDQEASAVDRLDGYRDVLFGTAPLLIERADYTRQGGVDAMAALLDRCPDLDAVFVASDL
                     MASGALQVLRERGRRVPDDVAVVGFDDLAPIAEHTDPPLTTVHQDVEGMGRLMARLLFS
                     RTEETGAAEVGPLSSVVTPTRLVVRKSA"
ORIGIN
        1 gcacgggcgg ggcctacgcc cccagcgccc gcgacaccgt gtagatcagc aggccggcca
       61 gcgaacccac caccgtgccg ttgatccgga tgaactgcag gtcgcggccg atattggcct
      121 cgatcttccg cgtggtgtgc tcggcgtccc agccggcgac ggtctcggtg atgagggagg
      181 tgatctcctt gcggtaggtg gtcacgacat gcacggccgc gccctccagc cacttgtcga
      241 ccttggcctg cgccatcggc tcggtcgcca tccgggtgcc cagcgacagc agggaggtcc
      301 gcacacgcag ccgcagctcg ctgcgctcgt cctcggcggc ggccacgatc atcgaccgta
      361 cggccgtcca ggcggaggcg atgaggtcct ggacctcgcc ccggccgagc acctcgccct
      421 tcagccgctc cacccgcgta cgcgtgtccg tgtcggactg gaggtcggtg gcgaagtcgg
      481 tgaggaagcg gtcgagggcg ccccgggccg ggtgggcggg cgagtcgctc atctcggtga
      541 cgaagcggag cagttccttg tagacccgct cgccgatcct ccggtcgacg aagcgtgggg
      601 tccagccggg ggcgccgccc tcgatcgcgt ccatgacctg tgtctcgttg aggatcagcc
      661 agtgctgggc gcgggcgcag accaggtcga cggcccgctt gtggccgccg tcggcgacga
      721 cccgctccag cagcttgccg aggccgggcg cgacctcctg ggcacccgcc cgccgggtga
      781 tcgcctcccc gaccacggcc tgcacgtccg agtcgcgcag gaccgtcagc gcgcccctca
      841 gcgcggtcgc cagctccgcc gtcacccggt cgacgttctg cggctcggcg agccacgcgc
      901 cgagccggct gccgatgccg acggcgcgca gccgctgccg tacgacgtcc tgggagagga
      961 agttctcgcc cacgaactca ccgagagtga cgcccagttg gtccttcttg gtggggatga
     1021 tcgcggtgtg cgggatgggc agcccgagcg gatgccggaa cagggcggtc acggcgaacc
     1081 agtccgccag cgcacccacc atgcccgcct cggccgccgc cgcgacatag tccgcccagg
     1141 caccggcgcc ctcgtgcgag gcccacttgg ccagcacgta caccaccgcc acgaacagca
     1201 gcatgccggc cgcgatgagc ttcatctgcc gcacgccccg ctgcttctcc tcgtcggcgg
     1261 cgctgaaggt ggtcatggtg cggtgcgaca cgcgcggctc ggcggccact gccgcttccg
     1321 ccacctcttc cgctttcgta cggtccattc actccacccg ttcctgtccc ccgtacacat
     1381 tgtcccgttc ttcggcgctt cagctcgtcg gctcgtcagt tcttcggctc ttcggctcgt
     1441 cagttcttcg atcctcggct cttcgcatgc ttggtgacgt actccataga tctactcaga
     1501 cctactcctg gaacggaaca ggagttcccc gcgtctgtcc gggcggggga accgatgggg
     1561 gttctcccca gccgcccccg tcccatgccg catcatgggg tgatcacatc ggagcctcgg
     1621 ggctccacag cccgaggagt aacacaccgc atgaccaggc aacacggtta tgcacttctg
     1681 gcggccatgg ccgccctggt cgtggcgatc tcggccgcga tatacatcgg cgtcggcatc
     1741 gacgacggca gccggcgcca ggagaccttc gcccgcgcac cccgcaacag cgccgccccc
     1801 gcctccaccg gcgtctgggt cggcgcctgg gcgacctcgc cgagcgggtc ggagccgggc
     1861 accgagacga acggcttcgc cggccgctcg gtccgcaacg tggtgcacac gacggccgcc
     1921 ggtacgagtg cccgcgtcac gctctccaac ctctacggcc agcagccgct gaccatcacc
     1981 cacgcctccc tcgcggtcgc cgccaccacg aacaccgcgg ccgccgcggc cgacaccatg
     2041 cgccgcctca ccttcgccgg caacccgacg gtcgtcatcg cggcgggtca gcaggtggtg
     2101 agcgacgtcg tacgggtggc gatcccgtac gacagcgacg tactgatcac cacctactcc
     2161 cccaccccgt ccggccccgc gacctaccac gcgcacgccc ggcagatctc gtacaccgcc
     2221 gagggcgacc gggcggcgga cgtcaccggg gagccgtaca ccacccagtc actgcactgg
     2281 cggtacgtca ccgccctgga cgtgctgagc aaagagtccg agggcacggt cgtcgtcctc
     2341 ggcgactccc tcaccgatgg cgtcacctcc accgtcggcg agaaccggcg ctggacggat
     2401 gtcctcgcgg gccgcctccg cgccgccgcc ggctcctcgg acacgccccg ctacagcgtc
     2461 gtcaacgagg gcatcagcgg caaccgcgtc ctcaccgacg gcaacggccg ccccgccgag
     2521 aaccccagcg gcctcaaccg cttccagcgc gacgtcctcg gccgtacggg tgtcaaggcc
     2581 gtcgtcatcg acctcggcgt caacgacatc ctcaggaacc ccggccgggc cgaccccgac
     2641 gccgtcaccg ccggcctccg ccaactcgtc gaccgggccc acgcccgggg cctccgcgtc
     2701 gtcggcacca ccctcatgcc cttccacggc caccgcggct actccgacca gcgggaatcc
     2761 gtccgccggg ccatcaacga ccgcatccgc tccggcgaag tcttcgacac gtacgtcgac
     2821 ttcgaccagg ccctgcgcga cccctacgac ccgcgtcggc tccggtcgga ctacgactcg
     2881 ggggaccacc tccacccgag cgacaagggc tacgagcgca tggcggaggt cttcgacctg
     2941 gagaaactga agggcgcggc tccagcggag ctgtagcccc gtaagggggc gcggggctct
     3001 gacatgtgcg gctccgccgc gtgggcgcga ccagcccccg cccatccgca ggcggcgaac
     3061 ggcctaacgc tccccccgcc tacgccgctc ccgctcccgc tccgacctca tcgcgtcccg
     3121 cgcctgttcc atcgcgtcgc gatgcgcgtc gtgcaggtcg tgcatgtggt cacggcgaga
     3181 ggcgtggagt tcgcgtcgcg cctgacgacg ttccagccgt tctctgcgcc gcgcctcctt
     3241 ctcccgctgc cgctcggcct tcggcacctt ccgctcgacc tcgaccccgc ccatgaacgc
     3301 gaacccggtg acgaccacgc ggggtgcccc gggctccccc ggctcatagt ccgcgctgtg
     3361 atcgaacccg cccatgatcc cgatcccccg gaccacgacc tcgacccccg gcggcacgac
     3421 cacactgatg ccgcccatga tcgccacgca gttgatggtg acctcgcgct ccgcgaagta
     3481 cgcgtcccgc agatccagct ccccgccgcc catgaacgcg aagcagtcga accgcttggg
     3541 cacggtccac cgccccttgc gctcgaatcc ggacatgacc gccacgcccc acgtggacga
     3601 gccctcgccg cccacgatcc gctcgggcca actcgcgccc tccgcaggcc tcttgacgag
     3661 cgagatggac gacggcggca cgacggccgg cggtgccacg gtccccgcgc cgggcagatc
     3721 acgggtgatc ggcgccagct cgccgtacgt ccgcgccttg tatgtcgcgt ccagcctctc
     3781 ctcgaactcc tccatgtcga gccgcccctc cgcgagggcg tcccgcagct gctcggaaac
     3841 tcgttcacga tcggcgtcgg aagcgcggag gtccatggcg gccggaagat ccggcaggtc
     3901 gtccgtcata cgaatcagcg tacgaggaac cccccacacc gggctacgag acggccccac
     3961 tcgtcgcccc gggctacgac acggccgcac ccctcccccc ggggctacga gacggccgca
     4021 cccctctccc ccggggccac gagacggctc ctcccctcgc cccgggctat ggcacggcct
     4081 gccccgtctc ccccacgcgc tcggcctgct gcgcgtacat ctgggcgatc acggcctcga
     4141 tgtccggctc ccgcaccgac aggtccacca gcggatactc cgacgcgatg cgcgccacca
     4201 gcggggccgc cgactccgac gcggggaacg cgagccactg ccggggcccc tcgacccgta
     4261 cgacccgggc gggcgctgcc tcgatcggcg gcagctcacg ctccaggtcg acgacgaggg
     4321 tgcgctcgct ctcgcccacc tcgtgcagcc cggtcagcgg cccgtcgtac atcagacgcc
     4381 cgtggtcgat gaccatcacc cgacggcaca gctgttcgat gtcctggagg tcgtgcgtgg
     4441 tcaggagcac ggtcgtgccc tgctcggtgt tgagctcctt cagaaactca cggaccttgg
     4501 ccttgctgat gacgtcgagc ccgatcgtcg gctcgtccag atacagcacc tcggggtcgt
     4561 gcagcagggc cgccgcgata tccccgcgca tgcgctggcc gagcgagagc tgccgtacgg
     4621 gtacgtccaa cagggcgccc agttcgagga gttcgacgca gcggtcgagg ttctcgcggt
     4681 aacgggcgtc ggggatgcgg tacatgcggt gcatcagccg gtaggagtcg atcaggggga
     4741 ggtcccacca cagggtcgta cgctgcccga acaccacgcc gatccgacgg gcgagccgcg
     4801 tccgctcacg ggacggatcg atgcccgcga cccggagccg acccccgctc ggcgtcagaa
     4861 tccccgtcag catcttgatg gtggtggact ttccggcgcc gttcggcccg atgtagccga
     4921 ccatctcgcc gcgtgccacg gtgaaggaga gcgagtcgac ggcccgcacc tcgcgccgct
     4981 cccggcgcag gaacccggtc ttcctccgga cgtcgaagac cttctcgacc cggtcgagtt
     5041 cgatgaacgc actgtctgcc acgtctgcca cggtcagctc cctgtactcc gatacgaacg
     5101 cagtcccgcc cgccacgcga cgcccgcgag cgcgcagcag gccacaccga ccagcggtgg
     5161 tgcgaaggcc agccaggtcg gcaggtccag cgggtagggg cggcccagga cgtacagccc
     5221 gggcacccag ttgacgaagg cgagcggcag gacgaaggtc acgccgcgca gcaggtcctt
     5281 ggcgaagagg gccggcgggt actgcaggag ggtcgctccg ccgtacgtga aggcgttctg
     5341 cacctcggag gcgtcctgcg cgacgaactg gaaggccgcg ccgccgacga acaccgccgc
     5401 gaagatcagg ccgccgctgc acaccatcag cgggatcatc agcaccttgg ccggtgtcca
     5461 ggcgatgtcg agcgtggtga gggcgtagcc gaggacgaac agcccctggg tgatccggcc
     5521 gaggcggcgc agcgcgaact tgtcggcggc gacctgggcg agcaccggca cggggcgtac
     5581 gaggagggtg tccagcgtgc cgtcgcgcac ccggcgcccg agccggtcca tggagccgat
     5641 catcaggtcc gcgagaccga aggagacggc ggaggtgccg tacagcaggg cgatctcggg
     5701 cagggagaag ccgcccaatt cgtcgacctg ggagaacatc agcaggatcg cgacgaagtc
     5761 gaaggaggtc gccgcgaagt tcccgaaggt cgtcatggcg aaggaggcgc ggtaggccat
     5821 cgtggagcgg atccacatgg cggcgatcat gcggtaggcg cgcagaccgt cccgtacgcg
     5881 gctgtacacg ccgtactcgc cgaaggggtt ctcctccttg atccgaacga ctgtgcggtc
     5941 gtcgaggtca gccaccctgg accaccacct tccgtgtcgc cgccgactgg atcagccgcc
     6001 cgaccgccag cagcaccgcc gcccaggcga gctggaaggc gtacgtgccc agcgggtcgg
     6061 cctcgcccag caggacgtcc gccggtgcct ggagcagcgc ggaccagggc aggatgcggg
     6121 cgaggtcgcc gagcgcgccc gggaagacgt tgagcgggag gagcatcccg gagaagaaga
     6181 ctccggtgag ccaggtgatc tgcatcgctc cggcgccgtc gaggagccag aacgcccaca
     6241 gggcgacgat gtaccggatc gcgaagctga cgagggcccc gagggcgacc gccacgaggc
     6301 aggcgagcca gggcagcggg ccggagggta aggccaggtc gaagaagagc gcgccgcaca
     6361 ccatggggac gacaccccgt ccgagcagtt ggaacagggc ccggcccatg tccgcggcga
     6421 gccaccacag ctggaggtcg acgggccggt acaggtcgac ggcgatgtcg cccgtgcgga
     6481 tgcgctcgat caactcctcc tcgaatccca cgcttcccag caccatcacc gcgaacatcg
     6541 cctggccgac ccatacatag gtgagtgcct gcgcctggtc gtagccgccg aggtggggct
     6601 tctcgtgcca gagggccagg taggtgtatg cgaggatgaa gccgaagacg gtgttggtga
     6661 acacccccgc cgcggtggcc acccgatatg tcgcgtaccg cctgaatcca ccggcggcga
     6721 cggcggcgta caaccgccct gtgcccacga ggaaaccccc atccgctgcg aagagttagg
     6781 cgcaatgccg aggccgagac cgattcgggc cgaagcggag aagcctagtc agcggccgga
     6841 gtgggctgcc acacgtttta cggggcggac ggtggcgctc gcggggcgta cggggcacgt
     6901 gccgggatcc gggaacggat cgaacggtgc gagagtcttt actcaggggc gcagaaccgg
     6961 cccggagcgg gcgcaaagcg tacgaggccg tacggaaatg aacgtacgac gcgaaaacag
     7021 gagcacggca gcacgatgag cgacgagccg cagcggaacg gcccgggctg ggcaccaaga
     7081 gaaccggagc cccgcgctcc gggcgcgact cccgagtccg ccgacaacac cgccaaggga
     7141 aggcccgacg gcacggcggg cgcggtgccc ggtggggggc ccgacgcggc gtccggcggg
     7201 aagcccggta cgacgcccgg cggggcgccc ggcgcggcgt ccggtgagaa gcccggcgcg
     7261 gcgtctggcg ggaagcccgg tacgacgccc ggtacgacgc ccggcgggag gcccggcgcg
     7321 gcgtccggcg ggaggcccga cgcggcgtcc ggcgggaagc ccggtacgac gcccggcggg
     7381 gcgcccggcg cggcgtccgg tgagaagccc ggcgcggcgt ctggcgggaa gcccggtacg
     7441 acgcccggta cgacgcccgg cgggaggccc ggcgcggcgt ccggcgggag gcccgacgcg
     7501 gcgtccggcg ggaggcccga cgcggcgtcc ggcgggaggc ccggtacgac gcccggcggg
     7561 gcgcccggcg cggcgtccgg tgagaagccc ggcgcggcgt ctggcgggaa gcccggtacg
     7621 acgcccggta cgacgcccgg cgggaggccc ggcgcggcgt ccggcgggag gcccgacgcg
     7681 gcgtccggcg gaaggcccga cgcggcgtcc ggcggaaggc ccgacgcggc gtccggcgga
     7741 aggcccgacg cggcgtccgg cgggaagccc agcacgacgc ccggcggaag gcccgacccc
     7801 acgcccggcg cgatgccagg tggcaagccc ggcgcagcgc ctggcggtaa gcccagcacg
     7861 acgcccggcg ggccgtccgg tgcggtgtcc ggtggccagt ccggtgctgt gcccggcagg
     7921 cagtccggtg cggcgtcggg cgggaagccc ggctcggccc ccggagggac gcccggcgcg
     7981 ggatccgccc cgacgtctga gaccaagccg acgccgccct ctgacgacaa gcccggcggg
     8041 gtcggcgacg gccggtccgc cggggcccgc gacgccaagc ctgctggcgc gcgtgacgcc
     8101 aagcctgctg gcgcgcgtga cgccaagcct gccggggcgc gtgacggtga ctccggcgga
     8161 tcccgtgacg ccaggcccgt cgccggacgc gacggcaacc ccgccggggt cccggacgcc
     8221 agggctgcca gggccgcgag ggccgccagg gctgccaggg ccgccggcgc acttggcggc
     8281 aaccccgccg gcctccgtga caaccggccc gtcgccggac gtgagggcac ccccgccgcg
     8341 acccctgagg gcacccccgc cgcgccccat gacgccaggc cctccggcgg acgtgacggc
     8401 cggcccgccg gagcccatga cggcaaggca tcccggacac ccacacccgc cgcggcatcc
     8461 ggcgcggccg gtgacgacac ccccaccacc accctgggta tcacgcccgc ccggccggtg
     8521 ccggacacac ccacccaggc cctgggcgtc atccccgccg ggaaggccac cgcgcccgcc
     8581 gccgtacccg acatcacgcc cgaccccgcc ggagcgggcg gcaaggcgaa gaagcccaag
     8641 cggcccaagc gcaccgggtt caggcggctg atccccacct ggcgcttcgt gctcagcgcc
     8701 ttcgtcgtcg ggctcatgct gatcatcggc gccttcgtcc tcggctacaa catggtccac
     8761 atccccaagc cgcaggacgc cgcgaccaag cagagcaacg tcttcctgta cgcggacggc
     8821 acccagatcg cccgcgacgg cgaggtcaac cgcgagaacg tgccgctgac gaaggtctcc
     8881 aaggaggccc agcgcgccgt actggccgcc gaggaccgcg acttctactc cgagccggcc
     8941 atcgacctca aggcgatggc ccgcgcggcc tggaacacgg ccaccggcaa gggcaagcag
     9001 tccggctcga cgatcaccca gcagtatgtg aagaactact acctggccca ggaccagacc
     9061 gtcacccgca aggtgaagga gttcttcatc gcgatcaagc tggaccgcga ggtgaccaag
     9121 gacgagatcc tggagggcta cctcaacacc agcttcttcg gccgcaacgc ctacggcatc
     9181 caggccgccg cccaggccta ctacggcgtc gacgccgacg aactcaccgc cgagcagggc
     9241 gcctacctcg ccgcgctcgt caacgcgccc agcatgtacg acgtcgtcgc ccaccccgag
     9301 aacaaggacg cggccgtcgc ccgctggaac tacgtcctcg acggcatggt caaggagggc
     9361 tggctcaagg agtccgagcg caccggcatg aagttcccga tgccgaagca ggccaccacg
     9421 tccagcgcct tctccggaca gcgcggctac ctcgtcgagg ccgtcaagtc gtacctcatc
     9481 aacaacaaga tcatcgatga ggaggcgctg gagaacggcg gtggctaccg catcaccacc
     9541 accatccagc ccaagatgca gaacgccttc atcaaggccg tcgacgacca gctgatggac
     9601 gaactcgaca agaagaaccg caaggtcgac aactacgtcc gcgccggcgg tgtctccatc
     9661 gacccgaaga ccggcaaggt catcgcgatg tacggcggca tcgactacac caagcagtac
     9721 gtgaacaacg cgacccgccg cgacttccag gtcggctcca ccttcaagcc gttcgtgttc
     9781 acctccgccg tggagaacgc ctccaacaac cagagcggcc aggcgatcac ccctaacacc
     9841 atctacgacg gcaccaacaa gcgccccgtg gtgggctggc ccggcgagac gtacgccccc
     9901 gagaacgagg actacgtcaa ctacggcaac atcaccgtcc gccaggccac ccagagctcc
     9961 gtgaactcgg tgtacgcgca gatggccgtg gacgtcggcc ccgagaaggt cgagaagacc
    10021 gcgatcgacc tcgggctccc caaggacacc ccggacatga acccgtaccc gtccatcgcg
    10081 ctgggcaccg ccaccgcgag cgtcctcgac atgaccgagg cgtacgccac gctcgccaac
    10141 cacggcaagc acggcacgta cacgatggtc gagaagatct ccaaggacgg cgaggcggtc
    10201 aagctgccct ccacggagtc cacgcaggcc gtcagccgca aggccgccga caccacgacc
    10261 gccgttctgc agagcgtcgt cgagagcggc accgccaccg ccgcgcaggc ctccggccac
    10321 ccggtcgccg gcaagaccgg taccgccgag gaggaccagg ccgcctggtt cgcgggctac
    10381 acccccgacc tcgccaccgt cgtctccgtc atggcccagg accccaagac gggcgcccac
    10441 aagtcgctgt acggcgcgat gggtctgccg cgtatcaacg gcggtggggc gcccacggag
    10501 atctgggcgc agttcaccaa ggccgccctg aagggcaaga aggtcaagga cttcgacctc
    10561 gacctccaga tcggcgccga cgtcgtcatc accccgccca gcacccccgc cgacgagccc
    10621 ggcgccaccg gcgaggagca ggacggcggc gccacgggcg aggaggagac cggccggccg
    10681 gacgacggca ccgacggcgg cacgaccacc ggcggcaccc ccgcgaccga cggcggaacg
    10741 acgtccaccg gcggcaccgc gaccgacggc ggcacaacat ccaccggcgg cagcacgaca
    10801 accgacggcg gaacgacgtc caccggcggc cccacaacgg acggcggaac gaccaccgac
    10861 ggaggcacca ccaccgacgg gggcacgacg gacggcggaa cgacgacagg gggcggggcg
    10921 acggagggga cgttcccata gcgccccata gctccccata caaaggggct ggtgacgatg
    10981 gtcgtcacca gccccttctg ttttcttcgc cttgacctca gagatacagg cccgtggagt
    11041 cctccgaccc ctcgaagcgg tccgcggcca cggcgtgcag atcgcgttcg cgcatcagga
    11101 cgtacgcgac gccgcggacc tcgacctcgg cacggtcctc ggggtcgtag aggacacggt
    11161 cgccgggctc gacggtccgg acgttctggc cgaccgcgac gacctcggcc caggcgagac
    11221 gccggccgac ggccgccgtc gcggggatca ggatgccgcc gccggaccgc cgctcgccct
    11281 cggcggtgtc ctgccgcacg agcacacggt cgtgcagcat ccggatgggc aacttgtcgt
    11341 gctgggtctt ctcactcacg ccccgaacct acctgccttc cctacccgtc ttcctcagga
    11401 cccgtcatcc tcaggccccg tcttcgtcag gccccgtcgc cgtcaggccc tacgacgccg
    11461 ggtcccgagg gcgagaagcc cgacgacacc gacgaccacg agggcgacgg gcacgatgcg
    11521 ctccacccgg ggcgcgccgt cctcgtcgac gaactggccc ctgacgtcac tgaccacacg
    11581 gttgaccgag acgtacgcct tgccgagggt gtggtcgagg ttggagacga ccttggcctt
    11641 ggcgtcgccc acgatggtcc tggggtgtac gcggacgccg atctcgtcga gggtttcggc
    11701 gaggttgtcg cggcgtcgct tgatgtccgc ctcgatctcg gccggggttc tgatgtccga
    11761 ggtctccgcc accgcgcggc ctcccgttgt cggtgaaatc tcttggttgc ggacagtctg
    11821 tcagctcgcc ccggcgccgt agtgccaggg cccgccatta cgctggaccg atgagcgagc
    11881 gactccagcc cggggacgtg gcccccgcct tcaccctccc ggacgccgac ggcaacgagg
    11941 tgtccctgtc cgaccacaag ggccgcaagg tcatcgtcta cttctacccg gccgccctga
    12001 cccccggctg caccaagcag gcctgcgact tcaccgacaa cctggagctc ctcgcggacg
    12061 ccgggtacga cgtcctcggc atctcccccg acaagcccga gaaactcgcc aagttccgcg
    12121 agaaggagtc gctgaaggtg acccttctcg gcgaccccga caagacggtc ctcgacgcgt
    12181 acggcgcctt cggcgagaag aagaactacg gcaagacata catgggcgtc atccgctcca
    12241 cgatcgtcgt cgacgagcag ggcaaggtcg aacgggcgct gtacaacgtc cgggcgacgg
    12301 gccacgtggc gaagatcatc aaggacctgg gcatctgaga cacgaccgcc cgcagacgcg
    12361 gcccgtaccg gaaccttccg gtacgggccg ctccgctttt cgggcgtgac cgtccgataa
    12421 acggttcgtt actccgtacg aggtcacgaa caggtgaccg gaacggaggg gaatcgatgg
    12481 gagccagtgc atacccgaag gagcggctgg aggaggcggc tcggggggcg cggacattgt
    12541 cggaggcgtt ggggagattg ggggtggatc cgaagagctc gacgcggcgg tacctcctcg
    12601 agcggatgaa gaaactgggg gtggatgtcc ccaggcgccg acccagcggg gcaaggcatg
    12661 gcgtccccga acgccggaag gcctgctcgt caagcagcag accggccagg ctcgacgcat
    12721 cccaagcgat cggctcaagt gggcgatgac gaccacgggc gtaccggagc gatgcgccat
    12781 gtgcgggacg gacgcagtgt ggcgagggca cccgctcccc ctggaggtcg accacatcga
    12841 cggtaactgg cgcgacaacc gcatcgagaa cctgcggttc ctgtgtccca actgccactc
    12901 gacgacggac acttaccggg ggcgcggcaa aggtcgtgcc tcatgagcag cggcgcgcag
    12961 tacacacggg aacggctggt cgaggctgcc gcgcagtgtt ccgacatcga cgaagtcatc
    13021 acctttttcg gcacccggcc gtacggcaat ctaccccggc acttgtacaa gcgcttcgac
    13081 cacttcggca tcgacatctc gcacttcaac cgctggttca ggctgcctcg ccccacagcc
    13141 gagcagttgc gcacggctgt tgccgagtcg gcctccatcg ccggggttct acgcaccctg
    13201 ggacggcccg acactggcag gcaacgcgca ctactgcgtc ggtggatcgc cgaggaggac
    13261 ctgacgacgg aacacttcct ggggcaagcg caccagcgag gcaagccagg cacggcccgc
    13321 gccaagcacc ccgacgaaat cctgatccag cacgacggca agcgtcggac gaagacccag
    13381 ctgctacgcc gcgcgctgcg cgaggtcggc gtccccgagg tatgcgccga ctgcggaaca
    13441 ggccccaagt ggctcggcaa acccatgacc ctggagatcg atcacatcaa cggggactgg
    13501 agcgacgatc gccgggagaa cctgcggttg ctgtgcccca actgccatgc gatcagcagc
    13561 acctggtgca ggggcggcag caaggcggcc tcacccggta aagtggggcg cggccaggcg
    13621 cccgtacgcc aagggctgag cggcaatctt taggtggttg tgtttgtcgg ttcgaatccg
    13681 accgggcgca cctgacaaaa caggccccgc accttagatt caaaggtgcg gggctcttcc
    13741 atgaagtcag cccaccaact cccgcagcac cggcaccagc ccccggaacg cctgcccccg
    13801 gtggctgatc gcgttcttct cctcagcagt cagctcggcg caggttcggg tctcgccctc
    13861 cggctggagg atggggtcgt agccgaagcc gttcgtgccc gtcggcacat gcctcagtac
    13921 acccctcagc tgcccctcga cgacccgttc cgtgccgtcc ggcagggcca gggccgccgc
    13981 gcaggtgaag tgggcgcccc ggtgttcgtc ggcgatgtcg ccgagctggg ccaggagcag
    14041 ctccaggttg gccttgtcgt ctccgtggcg gcctgcccag cgggcggaga agatgccggg
    14101 ggcgccgttg aggacgtcga cgcagaggcc ggagtcgtcg gcgatggcgg ggtggccggt
    14161 cgcctgggcc agggcgtggg ccttgagcag ggcgttctcg gcgaaggtga cgccggtttc
    14221 cttgacgtcg gggatttcgg ggtaggcgtc cgcgccgacg aggtcgtagg acagacctgc
    14281 gtcggcgagg atggccttca gctcggtgag cttgccggcg ttgcgggtgg cgaggatcag
    14341 gcgggtcatg cccccagtat cccggccacc cgtggcccgt cggttacgag gtgcagacct
    14401 tcgtcagttc gctcgcggcg ccggtgatgc cgctgatgtc gggggtcgcg tcgccgttct
    14461 ccacggcggt gcgggtgtcg gtgacggcct tctgaaggtc gtcgacggcc ttgttgacgt
    14521 cggcgttgtc ggtcttgtcg ccgatctcct tcaggttctc gtcgatggag ttgagggact
    14581 cctccagctg cgtcgggtcg ttcgacgcgt tctcgacggc ctgctggagg tcgcccacgc
    14641 tctgggcgat ggcctcggcg gtctggacgc agtccagggc cttgctcacg gcgtcgcagc
    14701 cggtggtgag cccggccgtg agagcgacgg cagctatggc tccggcgatg gtggtcatac
    14761 gacgtcggcg gctcgcggcc atggaacggt cctcctactg gttgcaggcc tgacggcccc
    14821 gggtacggct acttgccggt gtggccgggc gcacggtggt gtgccgggcg cccgtatgtg
    14881 caaggacgcg ggcggggccg ccgtggttgc cgtcgacggc cgccgctctt ggtgcttcct
    14941 ttacctttcg aggaccgtat caagcgcctt gcgctgcaga agcgccagct ccgtgcagcc
    15001 ggaaacggcc aggtcgagca gggagttgag ttcctcgcgg gcgaacggct cggcctcggc
    15061 ggtgccctgg acctcgacga aacggccgtc gccggtgcag acgacgttca tgtcggtgtc
    15121 ggccttcacg tcctcctcgt agcagaggtc gaggaggggg acgccgccga cgatgcccac
    15181 ggagaccgcc gagacggttc ccgtcagggg ctgacggccg gccttgatca gcttcttgcc
    15241 ctgggcccag gacacggcgt cggccagcgc cacgtacgcg ccggtgatcg cggccgtacg
    15301 cgtgccgccg tccgcctgca ggacgtcgca gtccagcacg atcgtgttct cgccgagcgc
    15361 cttgtagtcg atgacggcgc gaagggagcg gccgatcagg cgggagatct cgtgggtgcg
    15421 gccgccgatc ctgccccgta cggactcgcg gtcgccgcgg gtgttggtgg cgcgggggag
    15481 catggagtac tcggcggtga cccagccctc gccgctgccc ttgcgccagc gggggacgcc
    15541 ttcggtgacg gaggcggtgc agaagacctt cgtgtcgccg aaggagacga ggacggagcc
    15601 ctcggcgtgc ttgctccagc cgcgttcgat ggtgatcggg cggagctgtt cgggcgtgcg
    15661 gccgtcgatt cgagacatgg cgctgagcct agccgcacat acggaagggg ctcctcctgc
    15721 ggcggaaagg agcccctgtc catgagccgg cgtggctcac atcatgtctt cgatctccgc
    15781 ggcgatgggg tcggcgtccg tgccgatgac gacctggatc gcggtgccca tcttgacgac
    15841 gccgtgggcg ccggcggcct tgagggcggc ctcgtccacg agggaggcgt cgtggacctc
    15901 ggtgcggagg cgggtgatgc agccttcgac ctcttcgatg ttgtcgaggc cgccgagtcc
    15961 ggcgacgatc ttctcagcct tgctggccat ggccacgctc ctgtttccct gatccgagcc
    16021 gcgttccccg cggaaccgta cggggacagc ttgcaggact gtcccgcaac tggtctacac
    16081 cactggggga acggtcgcca aatgagggtg agcggggtgc tggctgcggc gcctatggat
    16141 gtgccgggtg atgttgtcgg gcggctgcgg gtttggtgtg gctggtcgcg cagttccccg
    16201 cgccccttcg ggggcgcggg tcctgcggac ccagcgcccc cgcccctgcg aagttcaggc
    16261 cgtcggggta tccgctgttt ccgagccctg gcccgggatg ggggatcctc cgtcgggggt
    16321 cggctgatcc tctgcggggg gttcggactt ggcgcggccc gcgtcgaggt tgcggagtgc
    16381 cggcagagcc acgatcgcga gggtgaccac gcaccaggcg atggcgagga gtgcgccggt
    16441 ctggcggagg ccgatccagt cgacggtgag accggcgacg agggtgccca gcgggacggc
    16501 ggtcatcgat acggcgttct ggagtccgag gacgcggccg cgcacctcct cggggatccg
    16561 ttcggtgacg aggaccagga agagggcggg cagcgggccc gcgccggcgc cggccaggac
    16621 ggcggccgcc cacatgacgg gcaccggagg caggagcgcg agccccgcga taccgatcgt
    16681 ggaggtgagc tgggcagcca cgaagacggt acggcgtgac cagcgggtgc cgatcgcggc
    16741 gtacaggcct gcgccggcga tgccgccgac ggcgaggagg gagaccacga cgccgaaacc
    16801 gccgggtgag tccttgccca cgaggtggac cgggagcacc aggttctgga gcggggcgag
    16861 gacggcgacg ctgccggccg agaccagggt gacggcggtg aggacgcggt cgccgcgcag
    16921 gacgccgagt ccgcgcttga ggtcgcctcg cagtccggcg ccgtcgccct gggccgtggc
    16981 ggtgggctgg gcgccgatgg tcttcgggag ggcgaaggtg acgagcgcgg cgagggccga
    17041 gcagccggcg gtgagccaga ggacggtcgc cgggtcgacg agcatgatga gtccgccggc
    17101 ggcggccggg gcgaggatca cgacgccgcc ggcgatgctc tcgcggagtc cggcgaggcg
    17161 ttccatgccg atgccggtgg cttcggcgat gtccggtgcg agggcctccc gggcggtcat
    17221 gccgggtacg tcgaagacgg cgccggcgac gccgaggacg acgaaccaga cgacggtgag
    17281 gccgaggagg ccgtcgacga cggggagtgc ggcgacgcag gcggcggagg cgaggtccgc
    17341 gccgatggag aggcggcggc ggccgacccg gtcgatgagc acgccgccgg cgacggccga
    17401 caggagcatc ggcagggcgc tcgcggcggc gacgaggccg accgcggtgg cgtcaccggt
    17461 gcgcagcagc accagccagg gcagggcgat cgaggccacg gtgttgccca gcagggacag
    17521 gccgtgggag atgaggtaga gcggcagcat cggggcattc tggtcgtggg ccgatggccc
    17581 gtcggatggt tgaccggcgt caccgccggg tggccggggg tccccggcag tccgggtctc
    17641 ccagcgaccg gggtcccgcg tggcgtgggc ccccgggttg ccgaggcttc cccaaatagc
    17701 cggggtctac cggcagtcgg ggttccctcg cccagcggtc gggttcccgg gtgttccggg
    17761 cccccggctg ccgaggcttc ccagctgacg gccatcgagg tcgagcggct cccggaggcc
    17821 ctgcgggact tccgggacac tccgaactcc ctcggcggcc gaggtttccc aacagtcggg
    17881 cttcccaggc agccagggct ccccatctgt cgagccttcc cgagaggccg ggacccccaa
    17941 gaggccggga cccccgagta accgggaccc ccggctggcc ggaggctccc ggctggccgg
    18001 aggctcccgg tcggtcggag gctcccggtc ggtcggaggc tcccggtcgg tcggaggctc
    18061 cggcgggatc aggcaggtgg gccgaacgca tagcgggaga tgtggccgat gtggcgtagt
    18121 accgggagcc tggcgaggat gtgggtgtcg atgcgcatcc ggcgccgcag tgtgcggggc
    18181 aggtggctca cgtcgacgcc cgccgccgtg gcgtacgcgc tgtcggtctc gatcagccgc
    18241 aatccgggta tcccgcgctc cagttcgcgt gggtcgttca cgccccacgc gagccgggca
    18301 cccgtcttgc ggaagagggc cagggagcgg gtggaccgta cggcgaaccg ggagtacgtg
    18361 tcgaacagca gctcgccctg cgggaagtgg gcgacgaggg tgcgcagcat gcggggcccc
    18421 tcgtcggcgg agaggtacat gctgaggccc tcggcgacca cgaggacggg gcggtcggtg
    18481 gggacctggg ccggccagtc cggttcggtg acggacgtgg cgagggtctc gtggccgggg
    18541 cgggcggggt agagctgttt gcgcagttcg atgacgtcgg gctggtcgag gtcgaaccag
    18601 cgcacccccg ggccgggggc gagacgttcg aacctgctgt cgaggccgca gccgaggtgg
    18661 accacggtgg actcggggtg cgcgtcgagg aatgcgcgga cccgccggtc gaaatagcgg
    18721 gcgcgcaggg ccacgccgac ggcggaggcc tctcccatgc cgagtcggtc gaagtcgtag
    18781 tcgatgcggt ccagcagttc ggccgcgatg tggtcgccca gcagggggtg ggcggagcgg
    18841 gcgtcgagcg cgcgggcgta gaggggtgcg agcagggtct ccgccgcgcc ggtcagggaa
    18901 atcttcacgc gacttctcgc ctctctggcg cacagaaata gggtcggcgg gaaatattga
    18961 ttcggcgagc gcagggtaaa gccctcggca gggattttcc gaccgacagg gacagctggc
    19021 gtcgactccc ggcgcgtcat gacacagcat acgcaaggag caccatacac cgtacaaccc
    19081 gaccggtctc actgtccacc acgcacccca cctgcgtata tgcgtacgac ctgcacacct
    19141 tccccgtcga tcacggagtt gatcacaaat acgtggccgc gcattgtcga gcagtgcatg
    19201 ccggacgaat gtttccagcc aacctatacc gatgctttgg gcactgttga ctcgcgtaat
    19261 tggcccttct acggtgattc gagttgccgc aaccggctcc gggggttgtt ttcgtgcctg
    19321 ccgccaaaaa cgtttctctt gtatcaatgc cttggaacag cgtcatccgg ccttcgattc
    19381 aggtcggtat tctgcgctcg ctcgccgaga gtgaaggctg gcaagtagac gcccgatatt
    19441 cctatctgga tttctacggg ctggcccaga gaatgctggg gttctccgac gagaagtggt
    19501 cggaggccta tgagctggtc tccgaaaagc tctaccacct ttcggtgggc gactggatct
    19561 tctcgtgccg ccggggtgat gccgagcggc gggaggcgta cttcgcccag ttgcgggcga
    19621 ggcgggtcga cgacacgtcg atcgagctgg tcgacgcgtt gcgcgaggtg gcggaccggc
    19681 atgtggagcg gacggccgcc gagctgctgg agtccgcgcc ggacgtcgtc ggcttcacct
    19741 cgatgttcag ccagaacggc ccgtcgctgg cggtcgcgga gcgcctgcgg gacctcggct
    19801 acggcggcgt gatcgtgctc ggcggcagca actgcgaggg ctcgatgggc agggcgctgc
    19861 tcgccaacta cccggcggtg gacgccatcg tggacggccc cggcgaggac gccttcgtga
    19921 ccctgctccg ccaggccgag gccggcggcc cgctccgtac gcgaggacgc ctggtcaccc
    19981 gcctgcccgc cgacgacgac gccgcgccgg ccgccccgct caccgccgct gccgccctgg
    20041 acgtacccac ccccaactac gacggtttct tcgagcagtt gcacgccgcc ggtctgcacg
    20101 gcctcgaatc cgagatcacc cttccggtgg agttctcccg cggctgctgg tggggcgcca
    20161 agacccactg caccttctgc ggcctcaacg gcgcgaccat ggcgtaccgg agcaagaacc
    20221 ccgacaccgt cgccgacgag ctgcggcatc tgatggaccg ctacggggtg ctcgacttct
    20281 tcgcggtgga caacatcctc gacctcaagt acctcgacac ggcactgccg tcggtggaga
    20341 agctcaacac cgaccactcg ctgttcttcg aggtcaaggc caacatggag tgggccgaca
    20401 tccgggccgt gcgccgggcg ggggtccgtt ccgtgcagcc ggggatcgag agcctcagca
    20461 cggaggggct gcggcatctc aggaagggtg ccacggcgta ccagaacatc cggttcctgc
    20521 tgggctgcgc cgagtacggc gtgcgggcgg actggaacat cctcaccggg tatccgcacg
    20581 agacgccgga ctccctcaag gcgcagctgg acgtcgtcgc gtcgctgacg catctgacgc
    20641 cgccgcacat cacactgatc cgcttcgacc ggttcagccc gtacgtcgag gcgcccgaga
    20701 gctacgggct cacgctgacc agcccgctgc cgggctacca gtacgcctat ccccgcctct
    20761 ctccggagga tctgtgggac atcgcgtacc acttcgaggg tgacttcacg gacgaccccg
    20821 acaacgggcc cgtgcggcgg cggctcgccg cgcgcgtccg gctgtggcgg gcgcaccacg
    20881 agtccgcccg cttcagctac cggctcggtt tcgactcggt caccctcacc gacgaacgac
    20941 ccgggctgcc gccgcacacc accaccctgc ggggcgagga ggcgcggctg ttccgcgccg
    21001 tcgtgggcgg cacccggttc cgcgacctcc aagggcagga gtggcagggg gaacgctggg
    21061 accaggccct ggaaacgctg cgcacctggc ggcgaaagcg gtgggtctac atcgaaggca
    21121 cgaaggtcat cgcactggcg gtacgcgagc agccctcggc ctaccgcacc ccaccgccca
    21181 agggcactcc ccggcgggct cgtacccccg tacccctcac gctcaccgct cgaccgtaag
    21241 gaggccgccc atcgcgcgga tgcgggccgc cgcgtacccc atgaggcacg gaaccgaaat
    21301 cgaacggcaa gccagaccga cgaaaggatc gagatatggg acccgtagtc gtattcgact
    21361 gcatgaccgc ggatttcctc aacgacgacc ccaacaacgc cgaactgagc gctctggaga
    21421 tggaggagct ggagtcctgg ggtgcctggg acggcgaagc cacctcttga gcgccggccg
    21481 gtgagtagcc ggcgggtgtg aagtcggcga gacggaccac cgggagaggg agcatgctcg
    21541 aagcgacggc gacggagtgt gagctgcgcg aggtcgtcca ccgttcgtat ccgtcggatc
    21601 gaacggtgac cgtgcggtgc accgtacgcc ccgccgaggg caccgcccag gccgacggct
    21661 acggcaccgc cacgaccgag gccgtggcac gggcgaaggc cctgtcggaa gccgtggagc
    21721 ggctggtggc gtgcaccccc ttcgcaacgg tcgcccgtcc gccgacgacc ccggcccccg
    21781 gctcgggctc cggtccggtc ccgcccttcc cggcggccgg ggtacggacc gcgccggacg
    21841 gctgtgcgag ccgggagtac cggccgctgt ccggggacgg gccgcgccgg gtgccgctgt
    21901 actggtcctc gccctgggtc gccggcgagg agttgcgcgc gggcacgctg tcggccgcgg
    21961 aggcgcggct gtcgagcacg gtcggctggg ccgtcgcccc gacgccggag gcggccctgc
    22021 gcggggcgct gctggagctg acggaactga tcgactacgg ggtcttcctg caccgtcgcc
    22081 tggcgggccc ggcgcggccc cggtcggcgg gtgacgagac gctggtggtg ccgctgggcg
    22141 gcgccgtccg tacgccgacc gtgctcgccg tggcgtacgg ccgcgggcgg ctgatgccgg
    22201 ccaccgggct gggctgcggg gcgagtcggg ccgaggcgac cgaccgggcg ctgctggagc
    22261 tcgcgcaggc cgagacgatg tggcggtcga accccaccgc cgagccggcc gagcgtttct
    22321 ttctgcgccg cttcgagcgg tggccgctgc tcacccggtg cgcgaccttg gacttcgagc
    22381 tcagcgatct gagtggtctc gacggtctga gcggtctcga cggtctgagt cgtctcgacg
    22441 gtctgagtcg tctcgaccat ccgagtgatc tgaacgatcc ggccggccgc ccggcgccgt
    22501 acgacgacgg gccacacccg gcgtcccccc tggaagagct ggaggccggc ggcatcaccg
    22561 tgtgggccga ctccggtgcc gtcgacatct caggcccgga catccccagg acccgtctct
    22621 gcttcgccca tgtggtgtcg gatccgcagc ccctcctggg ccttgtccgc gcaggcatcc
    22681 ccgtgttcga cacgggagaa gtgaggagga cccttgaccc gtcccgccga gacgcccacc
    22741 gagacacacc ccgaggcgca ccccgagacg cagcccgaga ccgatctgct gaccgcggcc
    22801 ctgctggacg gggccgccaa ggacgacgtt ccgcctgagc gcgagacggc catccagcag
    22861 gccctgtcct ccgtcgggga ctggctggcc gcggagcggc tgacggccga catccgcaag
    22921 tacggcatcg agtccgcgcc gacctacgag gtgcggctga cggacgccga gggcgcgctc
    22981 tgttcccgca gctccggcaa ggggctgggg caccggagca tggcgagcgc gctgttcgag
    23041 agcgccgagc actaccacct ggactggcgc cgggatccgc gggcgtcgga ggcggagttc
    23101 ctgccgggcc gggagatcgc gggccaggac accgcccggc ggtccgcgct gctgcgccgg
    23161 ctcggcggca tcatgccgga cgcgcccgtg ctgacccgta cgtaccgccc ggtggaggag
    23221 accctgaccg ggcgggcgga ccacggcccg gccgggcggc cgcaccggca ccccgtgttc
    23281 ctgcgtgacg gcggctaccg caactggccc cacccggacg acgaccggtc gttccagccg
    23341 ctgtggcact acacctccag cgccgggtac gcggcgggcg ccaccgtgca cgaggcgctg
    23401 gtgcacgccg tcaacgagct gatcgagcgg gacgcctggt cgtaccagct ggcccggtcg
    23461 tacttcgggc tgcccggcga ggggcccgag ctgcgggtgg tcgaccacga cacgctgccc
    23521 gccgaactgc gggagctgac gggcacggtc gaggaggtcc gcgaggcgcc ggtgctgatc
    23581 gtcgacatca cctgtgacac cggcgtaccg gcctatgtgg tgtgcgacgc gcggagccgg
    23641 gaggaggtgc ggctgatcgg cagcggggcc tcgccggtgc ggacgtacgc gttgcagcgg
    23701 gccctgctcg aatacctcca ggtgcgcacg atgttcgagc acgggccggt ggacgcggac
    23761 accgaggccg ggcagatcgc caccgcgctg gcccgctatc cccgccatct cgccgccgcc
    23821 cggttcgacg tcggtcaact gccgcacgag cggcgggcgt tcgacgcgga cgacgggctg
    23881 cccgcggccg cgagccccga gcagctgctg cggcatctcg tggaccggct gcgggacctg
    23941 ggcgtggacg tccaccaccg ggtgctcacg ccgccggggt ccgtcacggt cgtcgacgtc
    24001 gtcgcgccgg gcctggagat gttcgacaag gcgcgggcgg gctatccggt gctgccgacc
    24061 gggcggctcg gcgagcggct gcgaccgcgc aaggaccatg aaaggggcca cggagtggac
    24121 cacggaaagg accgcggagg tgcgccccgg tgaagctcgc gctcgtggca ccaccctgga
    24181 acagcctgta ccgcccgtcc atccagatcg ccaccctcgc ggcgctggag ggcacggggg
    24241 acggtgatcc gatcacaccg gtgtacgcgt acctggactg gttcgagtac gccgtcgacg
    24301 cgctggagtg cgatccggcg gagttcgtca ccgtctacga cacgatcggc gaggagctgt
    24361 acgggctcgg ggtcggggac tggatcttcg gcggggtcct ggacgcccat ggtcccgggg
    24421 aggaggcgga cgtccgcgac cggtacgccg ccttcctcac cgagcacggt gtggccgagg
    24481 agctggtggg ccgggtgctg gcgctgcgcg cggtggcgcc cgggttcgcg gcggggctcg
    24541 ccgggcggct cgtggcgacc ggcgcggagt gcttcgggtt caccacgtcg ttcagtcagc
    24601 tgatgcccgc gctggccgtc gcccgggccg tcaaggacca ggcgcccgag cggctggtgc
    24661 tgctcggcgg ggcgaactgc gaccggccca tggggcaggc cgtgatgcgg gcgtacccgt
    24721 tcgtcgacgc ggtcgtgcag ggcgagggcg aggcggcggt ggcggcggtc cgggccgcgc
    24781 gcggcgccgg cgacctcgcg gcggccccgg gcctggtcct gcggcacgag ggcgggctgc
    24841 gggtgtcgct gccgacggtg cagccggccg agtcggcgcc ggtgccccgg tacgcggagt
    24901 acttcgaacg gctgcgggcg ctgccgcacc gtgagctgat cgccccgcat gtggcgctcc
    24961 cgttccagat gtcgcggggc tgctggtggg gcgagaagct gcagtgcacc ttctgcgggg
    25021 agaacggcag cgggatggtc taccgcagca agccgggcga gcagctgacc aagaccctgc
    25081 gccggctgac cgaggagcac ggcgtgttcg acacgtacgc ggtcgacacg atcctcgcga
    25141 ggaacgacaa cggcctcgcc gaactcgccg cggcggaggt cgacatcacc acgttcttcg
    25201 aggtgaaggc caatctgggg ccgcgtgagg tgggcgagat gcgggcggcg ggcgtcacca
    25261 tggtgcagcc gggcatcgag agcctgagca gcggtgcgct gaagctgctg cgcaaggggg
    25321 cgacggcctt ccacaacctg cgtttcctgg tgctgtgcca ggagctgggc atcgacgccc
    25381 agtggaacct gctgtcggcg atgcccgacg agacggcgga gatgcttcag gagcagctgc
    25441 ggctgatccc gttcatcacg catctcgcgc cgccgtcgac ggtgagcaag gtccgggtcg
    25501 accgctacag cccgtacttc gagaagcccg aggagttcgg tatcgcgctg gacgggcccg
    25561 agccgaagta ccgcttcgtg cacgccggcc gcaccgccgc cgaacgcgcc gagctggcct
    25621 actcgttcga ccatgtggag ctggcggggc gggacgactc ggccatggcc gcggagatgc
    25681 tggcgctgcg gcggcgcctc ggggcccggg tgggcctgtg gaagaagctg cacgatcagt
    25741 cgcggttctc gttccggttc gggccgaaca tgaccgtgct gcacgacggc cggccgcatg
    25801 tcggcaccgg gcggcatgtg ctgcggggcg gcgacgacca gctgttccgc tgtctggtgc
    25861 acggcggacg gctgcaccag gccgtcggcc aggtcgccgc gatgacgggc cggccggagg
    25921 acgaggtgca cgcgagggta cgggagtggg cgcggcgcgg ctgggtccat ctggagggcc
    25981 ggcggggtct cgtcctcgcg gtgcgcgacg gcatgcggga cgagctgggc cgggcggcgg
    26041 agctgcggga ggccgcggcc gagtcggagc gtgccgccgc cgagtcgggg atggccggtg
    26101 cgggatcggg gagggtcggt gcgggacggt aacggcacga gccgtaggga cgtcttcgag
    26161 gtgttctccc gcgacggcac gccgatccgg ggcttcagca ggcccgggcc gggcgagacc
    26221 gtcgtcctcg tccacggtgt ggccatggac cggcggatct gggcggagtc ggggttcctc
    26281 gacgcgctcc cggacgccca tgtcctcgcg ctcgacctgc ggggacgcgg ggagagcggg
    26341 cgcgtcggca cggcggaggg ccacgccctg cgccggtacg tcgaggacgt ccgcgcggtc
    26401 ctggaccggt tcggccgcgc acggtacagc ctgttcggca cgttcttcgg cgggcggatc
    26461 gccctccagg tcgccgccgt ggacacccgg gtggcccggg cgttctcctt ctgcgcgcac
    26521 gccgagcagg tggagatccc cgaggacgcc gtcgaggagg aggcggtggc cgtcgagggc
    26581 cccggcgggc acgcctatct gcgcgaccac ttcaccgggc ggggcgcccc gccgtggatg
    26641 gtcgaggcct gcgcacgcgt cgaccccggt gagctggggg cggccacgcg gggtctgctg
    26701 cacggctccg accggcggac cgaacgcggc caccccgacc aggagttggt actgatcacc
    26761 gccgacggcg acgccgacct ggcccccttc cacgccgggg agcgccgcct cggcgcccac
    26821 ctgtggctcg tcgacgcccc gacccgcatc aaggccgcgg ggcgtctcgc ggaggtcggg
    26881 cggagggtgg cgggcgtact ggcggagggt gggcacggga cgggagacgc accggccgag
    26941 gcccgtacga ccggagacgc accggccgag gcccgcgcgt ccgggacggg ggtcgtatga
    27001 cggcgaccga ggacaccatg tggcgtcggc gacgggggct gctgcccgac ggggacccgc
    27061 tggtgcgggc cctggaggag ctggcggagc gcgggcgcgg gcatcggctg cgggccgtcg
    27121 ggctcgtcga ccccgccacc gggcggcccg gtcccccgca cgatctgacg gtgaccgacg
    27181 gcacggtcac cgcctggacc ccgacgccgc ccgccgccga cgggcgcgcg gcgccgtaca
    27241 cctcgtacgc cgtgccgggc ctcgtcgact cccacgcgca tgtctcgtcc gccgccgacc
    27301 tggtcggtct cctcgtccac ggtgtcaccg gcttccggca gctgtggggc gagccggcgc
    27361 atctgtacgc cgccggggtg caccgcgccc ggcacgccgt cctgccccgg ccctgggtca
    27421 ccgccggggt ggtcgacggg cccgggtcgc ggatcccgca gggggtcacc gtggtggacg
    27481 gggtccggtc ggtccggcag gtgatcgagg acgcgctggc gttcggtttc gacgggatca
    27541 aggtgtacga cgacgtcgcg cgcccggcgt tcgaggttct ggtccgggag gccgagcggg
    27601 ccggtctgcc ggtcgtgggc cacatccccg aggcggtgcc cctggacctg gcccagcgca
    27661 cgttgcggtc gtccgagcat ctgtacggca tcgtgcccaa tgtgttccgg ctgccgcccg
    27721 agcggcgctg ggacgcgctg gcggcggccc tgcgcgacca cccggcaccc ggggccgtac
    27781 ccggccactt cgtctgcccc accctcgtct gctggcgggc ccgcagcggt gagcgccggt
    27841 acacccgccc ctcccgcgcg gccctccagg cggtggacga gggccgccgc cggtcctggc
    27901 agtcggcggc ccgggacgcc ctccggctgg acgccgccga ggcgcaccgg cgcggcggcc
    27961 tcgtcgacgg gctgggccgg atcgcccgcg ccctcgccga cacgggcacc cggctgctgg
    28021 cgggcaccga ctgcggcaac ccgttcgtcc tcgccggccc ctccttccac aaggagctgg
    28081 ccgaactgtc ccgcgcgggg ctcgacttcg gcgccgtact gcgggcggcg accactcacg
    28141 cgtacgaggc catggggcgg cgggcgggcc cggtgcccgg tgatccggcg gacctggtcc
    28201 tctaccggcg gccgcccgac ggcgacgtga ccgccctcgc ccggcccgac gcggtgctcg
    28261 tcgacggagt cctgctcgac ggcaccgacc tcgaccgcct gtgggcgcta cgcctggccg
    28321 cgtccggcct cgacccgtcc ggctgggccc gcggcaccct cgacccaccg gtcaccaccg
    28381 gccgacccac gaaggagaca gcccatgcag gctgaccggg aacccgaccg cacggggcgg
    28441 gaggcgaaac gccccgcaga acccgaccac cccccacagc aggccacatg ccccgtcgac
    28501 ttcgacttct tcgccgcgcc gcagacgtat cgcgacgccg ccgccgaaca cgccggtgag
    28561 cacggcgcct tctacagcga ccggggcttc tgggtgctga cgacgtacga cgggatcgtg
    28621 gacgcgttca aggacgaggg caccttcacc gtcgggcggg tcagcgcggc ggagggcgcc
    28681 gaggaggagc gctggatccc gctgaccgtc gagggccgcg agcacacggc gtggcggcag
    28741 cgactgggtg cctggttcac cccgcagcgg gtgcgggagc tgaccccgtc gatgcgtgcg
    28801 ggtgcccggc ggcggatcga ggggttcctg gagaagggcg aggtgtcgtt caacgaggac
    28861 ttcgcccggc cgtacgtcct ggagaacctg atgacggccg tgggctggcc cccggacggg
    28921 ttcgacctgc tcatcgccat caaccgggcg atgatcgact cccgttcggc accggacccc
    28981 agggcggcgg cgtacggcga actcgggctt ccggcgctgg agcggttcgc ccgggaacac
    29041 attgcccggc ggcgcgcgga gcccgccgac gacctgacca ccgccagctt cggctgggag
    29101 atcgacggtg ccgaggtcac cgacgacgac cgtgcctccc tgctgtgcac gctgttcctg
    29161 gccggcatcg actcgacggt gaaccatctg gccaacgccg tccagcacct cgcccaccac
    29221 gaggaggacc ggcggcggtt cctcgccggg cccgaggtcc ggccgccggc ggtcgaggag
    29281 ttcctgcggg ccaactcgtg catgtacccg ggccggcagg ccgcgaccgg cggcgcgggc
    29341 ggggtcgcgg accggggcga caccgtgctg cttccgctcg ccctcgccaa ccacgacccc
    29401 gaggtgttcc cggagcccgg ccggatcgac ttcgaccgga cgcggaaccc gcacatcgcc
    29461 ttcggcaccg gcccccacca gtgcctcggc gcggccttcg cgcgcgccca gatcctggtg
    29521 gccctggagg agtggcacgc cctcgtcccg gactacgcgc cgtcccccga gcagcgcacg
    29581 gccgaaccac cgttcctgcg caactcctac gacctgaggc tcgtctggtg agggcgccat
    29641 gaccggaacg accgagagga ccgaggcgac cggcccggcc gatgtgaccg gcacgaccga
    29701 gccgaccttg gccaccactc cgacagaacc cgccaccccg tcagtgccca cccgaccagg
    29761 ccgggccgcc ctcgtctcca tgccctggaa caacgtccgc cgcccctcca tccaggtcgg
    29821 caccctgcgc tccgtcgccc gcaccgaggg gtggcgggtc gactcgcact acgcctacct
    29881 ctccttctac ggcctcgccc gcacggccct cggcatgcgg gacgccgagt ggtcgcaggc
    29941 gtacgagacg gtgtccgagg ggctgtacca gctctccgtc ggggactgga tcttcgcgtg
    30001 ccgcgacggc ggggcggcgg cgcgcgaggc gtacttccgg atgctgcgca ccaagggcgt
    30061 cgacgacgcg acgatcgagc tggtcgacgc gctgcgcgag gtggccgacc gccatgtgga
    30121 gcggacggcc gccgagctgc tggaatcagc ccccgatctc atcggattca ccagcacctt
    30181 cagccagaac ggcccgacgc tggccgtggc cgagcgcctg cgggacctcg gctacggcgg
    30241 cgtgatcgtg ctcggcggca gcaactgcga gggctcgatg ggccgcgccc tgctcgccaa
    30301 ctacccggcg gtggacgcca tcgtggacgg ccccggcgag gacgccttcg tcgccctgct
    30361 ccgccaggtc ggggccggcg acccgccgcg ctcccacggc cggctgatca cccggctgcc
    30421 cgccctcgcc gacagcgccc cggccggcat ctccgccggt cagtcgctgg aggtgcccac
    30481 ccccgactac gacggtttct tcgagcagtt gcacaccgcc ggcctgcaca ccctcgaacc
    30541 ggagatcacc cttccggtgg agttctcccg cggctgctgg tggggcgcga aaacccactg
    30601 caccttctgc ggcctcaacg gcgcgaccat gacgtaccgc agcaagaacc ccgacaccgt
    30661 cgccgacgaa ctccgccacc tcatggaccg ctacggcgtc ctcgacttct tcgccgtcga
    30721 caacatcctc gacctcaaat acctcgacac ggcactcccg ctggtcgaaa agctcaacac
    30781 cgaccattcc ctgttcttcg aggtcaaggc caacatggaa tgggccgaca tccaggccgc
    30841 ccgtcgcgcc ggagtccgct cggtccagcc gggaatcgaa agtctcagca ccgaggggct
    30901 acgactgctg aagaaaggcg cgaccgcctt ccagaacatc cgtttcctgc tcggctgcgc
    30961 ggaattcggt gtcctgccgg tgtggaacat cctcaccgga tttccccacg aaaccccgga
    31021 gtcgatgctc acccagatcg atctgctgcc ttccctgacc catctggaac cacccgacaa
    31081 cgacatcctc gccgtgcact tcgaccggtt cagcccgtac gtggaacacc cgcaggacta
    31141 cggtctcacc ctgacccacc cgctgcccgg ctaccagtac gcctatcccc gtctctcccc
    31201 cggcgacctg tgggacctcg cctaccactt cgagggcgac ttcaccgagg acccccgcaa
    31261 caccgccgtc cgcgaacgcc tcgccacggc cgtccaccac tggcgcaccg agcaccaccg
    31321 ggcccgtttc acctaccgcc tcggcttcga ctccgtcacc ctcaccgacc accggcccgg
    31381 cctgcccgcc cacaccaccg tcctgcgcga cgaggacgcc cggctcttcc gcgcgatcat
    31441 cggcggcacc cgattccgcg atctccagaa tcaggaaggg cgagacgggc agcccctgga
    31501 aaagctccac acctggcagg agaaaaggtg ggtctacatc gagggcacga aagtcatcgc
    31561 cctccccgta cgcgaaaaac cctccgccta tcggaccccg ccccgcaaag gaactccccg
    31621 caggtcccga actaccgtgc ccctcacgct caccggtccg cctccgccgc ggcggcctgg
    31681 ctgaaatccg tcccgtacgg cgtttcccgt ttgcggtgac cgcccgtcgg cgcggtactc
    31741 gtagaggatc accgtgcacg gctccgagca ccacacacga cacaccgcac cgacaccacc
    31801 acgcagcacc gagcacaacg ccgcatcacg acccggaagt tgatcactat gaccacggcc
    31861 cccaccgagg accagacccg cgccgaggac ctgccgccgt cctgccgcga tctgatcggc
    31921 atcctcgccc agaccgaccg gcgcgacgcc ttcgcggccc tcgcgctcgg cgcgacctcc
    31981 gtggcacagg tggcggagcg ggcggggctg cgcccggccg ccgccgccgt cgccctgcag
    32041 aagctcgtcg acgggcggat cgccgcgtac gacgccgacg cccgcaccta ccggctgatc
    32101 gacgacacgt tccggctggc cgtccaggcg gaggtcagga tctccggacg gggcggcggt
    32161 gacggcgcgg gggcctactt ccgcaaggga cggctgacct cgatccccgg caaggccgag
    32221 gtccgcagcc gggtgctcgc cgtcgtggcc gactccttcg aggccggtgt cacctactcc
    32281 gaggccaagg tcaacgcgat ctgcggccag tggttcgacg actgggtgac cctgcgccgg
    32341 gcgctcgtgg acgaggacct gctgcgccgc gacgagtcgg gcacgcagta cgaacgcgta
    32401 tgaccgcatg acacgggtcg tggcgggtga cgtcggcacg gacacgccgg ataaggccgg
    32461 taccgccgat accgccaaag cagcagatac cgccgatacg gcgagccggg cggccgacgt
    32521 cgtcgcgtgc ggccggcaca ccggcgcggc cgtcggcgcc ttcagccgcc gccggggctt
    32581 cgtggcacgg cccgggcagg tggtcgccga gccgtccgcc gacggccgcg cggtggtgct
    32641 caacgtgggc ctggggcccg ccggttcggc cacggccgcc acgttccgcg ccgcggctgc
    32701 cgcctcggta cgggccgtgg gccccgcccg tacgctccgc ctcgacctcg cgctggccga
    32761 cggcagcggg gtcccggccg ccgagcgggc ccgggccgtg gcggagggcg cggtgctggg
    32821 cctgtaccgc tacgacgagt accgctccgc tcgggccgcg agcccgctgg ccgaggtgat
    32881 cgtggcgacc ccggagcggc gggccgtcgc cgagggcctg gccgccgccg aggccacctg
    32941 tctggcccgc gacctcgtca actgcccggc cgggaccctc actcccccgg cgttcgccga
    33001 ccggatccgg gagctggcgc acaccgccgg cctcgactgc gcggtgtacg agggagccgg
    33061 cctgacggag ctgggcctca cgggcctgac cgccgtgggc cggggctcgg cggaaccgcc
    33121 ccggtacgtg gagctgacgt acgacccgcc ggatgccgac cccgcgctca cggtcggcct
    33181 ggtcggcaag ggcgtcacgt tcgactccgg cgggctgtcc ctgaaaccgt ccggcgagcg
    33241 gcacgcgatg aaggccgaca tgggcggcgc ggcggccgtc gtcgccgcgc tgaccgcact
    33301 gccccgcctc ggcctgcccc tgcgggtacg cggccacctc cccctcgcgg agaacatgcc
    33361 ggacggcggc gccctgcggg tgggggacgt cgtacggcat ctggacggta cgaccacgga
    33421 gatcacccac acggacaacg agggccgggt ggtgctggcc gacgtcctgg tccgcgcgag
    33481 ccgccccggc ccgcaccgca gcgacctcgt cgtcgacgtg gccaccctca cctccgccgc
    33541 cgtccacgcg ctcggcaccc gcaccggggc cctgttcaca ccggacgacc ggctggccca
    33601 gacggtgctg gccgcttcgg agcgggccgg ggagtcgttc tgccggctgc cgctgctcgc
    33661 ccatgagcgg cggaacctgc gctccgccgt ggcggaccgg gtgaactgct cgcaccggca
    33721 cggcgacacg atccaggcgg cgctcttcct ccaggacttc gtcgcggccg gtgtcccctg
    33781 ggcccatctg gacatcgccg cgcccgcgta caacgacgag ggcccgtacg ccgaagtgcc
    33841 gtacggcggt accgggttcg cggtgcgcac gctgatcgag acgctgcgcg ccctctccga
    33901 aggctcaccg gacgtcccct gaactctcac cgggcgctcc gcgagccgtc cgcgtgccgg
    33961 gtaggaatcg agggttcctg atcgcttccc catctgctac aacaggtcta caccactgag
    34021 tggtgtagac caccacccga tggaggaagt ctatgagcac cgccaccgcg ccctcggcgg
    34081 cgcccgcgaa aaagtgggga tcaggcctga tgcagggcct gcagaaggtc ggccgcagcc
    34141 tgcagctgcc catcgccgta ctgccggccg ccggcctgct ggtccggctc ggccagccgg
    34201 acgtcttcgg ggccgagggc ctcggctggg acaaggtcgc cgcggtcttc gacaaggcgg
    34261 gcggcgccat caccggcaac ctcgcgatgc tcttctgcat cggcgtcgcg atcggcttcg
    34321 ccaagaaggc cgacggctcc accgccctcg ccgcgctggt gggcttcctg gtctacagca
    34381 aggtcctgga agcgttcccg gtgaccgagg ccgagatcac caagggcgcg gacgtcgccg
    34441 cgacgtacaa caaccccggt gtcctcggcg gcatcgtcat gggtctgctc tcggcggtcc
    34501 tgtggcagcg gtaccaccgc aagaagctgc ccgactggct cggcttcttc aacggccgcc
    34561 gcctggtgcc gatcatcatg gccttcgtcg gtgtcgcggt cggtgtcttc ttcgggctcg
    34621 tctgggagcc gatcggtgag gtcatcggca gcttcggcga gtggatgacc ggcctcggtt
    34681 cggccggcgc ggccctgttc ggcgcgatca accgggcgct catcccgatc ggcatgcacc
    34741 agttcgtcaa cacggtggcg tggttccagc tcggcgagtt caaggacgcc tccggcgtgg
    34801 tctcgcacgg cgacctgagc cgcttcctgg ccggtgaccc gaccgccgga atgttcatgt
    34861 ccggcttctt cccgatcatg atgttcggcc tcccggccgc ggccctggcc atcgcgcaca
    34921 ccgcccgccc cgaacgccgc aaggtcgtca cgggcatgat gatctcgctc gccctgacgt
    34981 ccttcgtgac gggtgtgacc gagccgatcg agttctcgtt catgttcatc gccccgctcc
    35041 tctacgtgat ccacgcgctg ctgaccgcgc tctccatggc catcacctgg gggctgggcg
    35101 tccacgccgg cttcaacttc tccgccggct tcatcgacta cgccctgaac tggaacctgg
    35161 ccaccaaacc ctggctgatc atccccatcg gcctggtgtt cggcgccatc tactacgtcg
    35221 tcttccgctt cgccatcatc aggttcaacc tccccacccc gggccgcgag cccgacgagg
    35281 agatcgagga cctcaccaag gcgtgagcag ccccggaaac gacgtcgggc ccccggagcg
    35341 tctcgctccg ggggccctct tcatgcatac gggcgtacga acgtacgggg tcagatctcg
    35401 tacgacatcc tgggcaccgc cagctccacc gggccgtcgt acacctcgcg ggcgtcgacc
    35461 aggttgacct gcgggtcggt ccacggcggg atgtgcgtga ggacgagacg gcgggcgccc
    35521 gcccgggcgg ccgtctcacc ggcctcgcgg ccgttgaggt ggaggtccgg gatgttctcc
    35581 ttgccgtggg tgaaggcggc ctcgcacagg aacaggtcgc tgtcgcgggc cagttcgtcc
    35641 agggtgtggg tgacaccggt gtccccggag tacgtcagga cccggccgcc gtgctcgatc
    35701 cggatgccgt acgcctcgac ggggtgggcg acccgttcgg tgtggatggt gaaggggccc
    35761 agctcgaacg tgctcggctt gaccgtgtgg aagtcgaaga cctcgctcat ggaggaggcc
    35821 gacggggtgt cggcgtaggc cgtggtcaga cgctgctcgg tgccctccgg tccgtagacc
    35881 gggatggggt cgcagcggcc gccgtcatgg cggtagtagc gcgcgacgaa gtacgcgcac
    35941 atgtcgatgc agtggtcggc gtgcagatgg ctgaggaaga tcgcgtcgag gtcgtagaga
    36001 ccgcagtggc gctgcagctc gcccagggca ccgttgccca tgtcgagaag cagccggaag
    36061 ccgtcggcct ctacgaggta gctcgaacag gccgattccg cggacgggaa cgaccccgag
    36121 cagccgacga cggtgagctt catgagagct ggaacctccg cgctggcgtg aagtcgtgac
    36181 agtcgtgtca gtcgtgacgt gcagacgggt tgcggattgc agagtgcgtg acggatgcgt
    36241 ggtgcggatt gcagttggcg gggttgccaa ggacggacgt gggtgcagca agggttgtgc
    36301 ggtccgatga gcgtaaggcg caaaagggtg ggtcgctcct ccgccagggg ctgttgtggg
    36361 cgaactcacc tgtggtgtca ccggttcggc tggtggtggg gccgttgggg cgcgcgtggg
    36421 ccggggtgag gtggcaccga agggcgcggg agcgtgcgac agggcgggcg tggcgcggtg
    36481 tgcgccggta ccgtcggggc tatggacacg tcctggtggt tggcgctcgc ggcggtggtg
    36541 ctgctggcgc tgctcgcgac cgtggtcgac gggtgggggc ggtcgcgacg gccgtcgagg
    36601 cgatcggagc ggccgggtgg gcggacgcgg ccgccggggc gccccgggcg tgcgcgcggg
    36661 cccgtgccgc ggccccggcc gtccgagatc tggtgggcca gcgtcccctt cgaggacggg
    36721 cccggcggca aggaccgccc ctgcctcgtc ctggccgtcc gcggggaccg cgcccgcgtg
    36781 gccaagatca ccagtcggta ccgcgacgag cgggccggtg tgattcccct cccgccgggc
    36841 acggtcggcg atgcccgcgg ccgtcccagc ttcctggaga cgggggagct gcgtgaggtg
    36901 cccgtgggtg acttccggag gaaggcgggg gtggtggacc cggtgctgtg ggaccagatc
    36961 cgccgcctgt cgaactgacg gccacgcgtc gggggacagc cgcttgtgtg ccgactgcgg
    37021 gtgggtgggg gttgctcgcg cagttccccg cgcccctgaa agaccccgag ggcgacccat
    37081 gctgttaagg ggcgcgggga actgcgcgag caaccacaca caccccgcac ccgccgacca
    37141 atcgcacccc ccgagctact gggcgcccaa ggggtagaag gggcccagcc cctacgccca
    37201 gaactcccct acgcccagag ctggccctgc agcgtctcga tcgcctcttc cgtcgtcgcc
    37261 gccgtgtaga cgcccgtcga gaggtacttc caacccccgt cggccacgac aaagacgatg
    37321 tcggccggct cgccggactt caccgccttg ttgcccacac cgatcgccgc gtggagggcg
    37381 gcaccggtgg agacaccggc gaagatgccc tcctgctgca gcagctcacg ggtgcgggtc
    37441 accgcgtcgg cggagcccac ggagaagcgg gtggtgagga cggacgcgtc gtagagctcg
    37501 gggacgaagc cctcgtcgag gttgcggagg ccgtagacga ggtcgtcgta gcgcggctcg
    37561 gcggcgacga tcttgacgtc cggcttctgc tcgcgcagga aacggcccac gcccatcagc
    37621 gtgccggtgg tgccgagacc cgccacgaag tgggtgatgg aggggaggtc cgccaggatc
    37681 tcgggaccgg tcgtcgcgta gtgggcgccc gcgttgtcgg ggttgccgta ctggtagagc
    37741 atcacccagt cggggtgctc ggcggagagc tccttcgcca cccgcacggc cgtgttggag
    37801 ccgccggccg ccggcgaggg gatgatctcg gcgccccaca tgccgagcag ttcgcgccgt
    37861 tcctgggagg tgttctcggg catgacgcac accatgcggt agcccttgag cttggccgcc
    37921 atggcgaggg agatgcccgt gttgcccgag gtgggttcca ggatcgtgca gccgggcgtc
    37981 agacggccgt ccttctccgc ctgttcgatc atgtgcaggg ccggccggtc cttgaccgaa
    38041 cccgtcgggt tgcggtcctc cagcttcgcc cagatacgga catcggcgga cggcgagagc
    38101 cgcggcaggc gcaccagagg ggtgttgccc accgcggcca gcggggagtc gtatcgcata
    38161 cgggatcagc ggccgatcgg atcggaggcg gaggactggg aacgcatcag accatgccgc
    38221 cggccaccgc cggcaggatg gtcacgttgt cgccgtcggt cagcttggtg ttgatgccgt
    38281 ccaggaagcg gacgtcctcg tcgttcaggt acacgttgac gaagcggcgc agctcaccgg
    38341 cgtccacaat gcgggcctgg atgcccgtgt gacggctctc gaggtcggtg aacagctcgg
    38401 cgagggtggc accggctccc tccaccgcct tctgaccgtc ggtgtactgg cggaggatgg
    38461 tggggatgcg gacctcgatg gccatggtgt gcggctcctg tcgggagtag tcggtcggtg
    38521 gcgcgcggca gcgcgaagtg cgtggtcaca cagctggtgg cgccgcggct cacagccgta
    38581 cggcggcagg ggtcggcgtc aacagatggc gctggcaagc ctgcacaggt cgacgtgcag
    38641 ccgcgccacg agcagtgcgc ccggcgtctt ctcgctcacg tcgtcaagaa ccatgcgctc
    38701 atcgtatcga ttcccggtcc gggtcccgga aggtgatccc atatgccgga cgcatggggg
    38761 ccggggaatg agaccggaca cctcagcgac ccggtcaggc cgacttccgt acgaccagac
    38821 gcgtgggcgt gaccaccgag gacagcggcc ccacctccgc cgcgcccgtc tcctccgtac
    38881 ggctgaacag cagccgtgcc atcagccggc ccatcccctc gacgtcctgg tggacggtgg
    38941 tcagcggcgg atcggtgtgc tcggcgatgg gcgcgaggtc gtcgaagccg acgacggcca
    39001 cgtcgtccgg cacccggcgc ccgcgctcgc gcagcacctg gagcgcgccg gaggccatca
    39061 ggtcggaggc gacgaagacg gcgtccaggt cggggcaccg gtcgaggagc gcggccatgg
    39121 cgtcgacgcc gccctgccgg gtgtagtcgg cgcgttcgat caggagcggc gcggtgccga
    39181 agaggacgtc ccggtagccg tccaggcggt ccacggcgga ggcctcctgg tcgcacggtc
    39241 cggtgatcgt cgcgatgcgt tcccggccca gcgagaccag atggcggacg gcctcgcggg
    39301 ccccgccccg gttgtcggcg tcgacgtaca cacagtcgcg cacgggctcg ccctcgcgga
    39361 ccagcggccg gccgccgaag acggcgggca ggccgagccg ttcgatcatg ccgggcagcg
    39421 ggtcgtcggc gcgcagggag aagagcaggg cgccgtcgac atggccgccg cccaggaagt
    39481 cgccgacgcg cgggtactcc tcgggctcct ccaggaagag gaggacgggc tgggcgccgt
    39541 gggccaccag ctccttgcgg atgccccgga ggtggaggtc gaagaagggg tcgatgaaga
    39601 gccggttctg cggctggctc gccacgacgg cgatcgcgtt gttgcggcgg gtgaccagct
    39661 gccgggcggc ggagttcggc acatagccca gctcggcaat cacttcccgg acccgctcga
    39721 cgacctccgc gcgtaccttg tcctcgccgt tgatcacccg cgacacggtc gacttggaca
    39781 ctcccgagcc gcgtgcgaca tcgtcgagcg tggggcgccg gccgtgcggt cgtcgcgtct
    39841 gtcgtgtcaa caccgtctcc gtcgcgggct gttgtgtgcg tgcgcgtgcg tgcgtacgca
    39901 caccgtaacc gcgaaggctg
//
