LOCUS       BGC0000513              6203 bp    DNA     linear   BCT 27-FEB-2015
DEFINITION  Saccharopolyspora erythraea NRRL2338 complete genome.
ACCESSION   BGC0000513
VERSION     BGC0000513
KEYWORDS    .
SOURCE      Saccharopolyspora erythraea NRRL 2338
  ORGANISM  Saccharopolyspora erythraea NRRL 2338
            Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
            Saccharopolyspora.
COMMENT     Project: 18489.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 19:44:01
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4704393
            Orig. end    :: 4710596
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..2535
                     /locus_tag="SACE_4230"
     CDS             1..2535
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_4230"
                     /db_xref="EnsemblGenomes-Tr:CAM03499"
                     /db_xref="GOA:A4FHH4"
                     /db_xref="InterPro:IPR000719"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="UniProtKB/TrEMBL:A4FHH4"
                     /function="15 Serine/threonine protein kinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 84.9;
                     E-value: 1.1e-25)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SACE_4230"
                     /product="serine/threonine protein kinase"
                     /protein_id="CAM03499.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-14, bitscore: 42.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1083.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5.3e-10, bitscore: 27.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAFCFADPLFFDEQRRHSGTQDEYARQLPEPGDDWVRSAL
                     GTWHMLRPAEVVLPAQGWKVHVSATLGNAERVLAAVHRYCLRERVAFKHLRSPRVLLAR
                     NAKYAPRSASGKLVTIYPVDDEHLATVLTELAPQLRGEPGPYILSDLRYEQGPLYVRYG
                     GFAERWVEFDGTRVLAIAGPDGELVPDKRNPGFSLPDWVSPPECLSASLAARKGGDRAA
                     FGYRVTSSMHFSNGGGVYRAVRKSDGAEVVLKEARPHAGLDRDGTDAVARLHREHEVLR
                     RLDGIGGVPAVHELFQLWEHTFLAMDLVPGTPLGTWLARTYPLTRQHPTEQEIADYTRR
                     ALALLERVERLLDRVHGRGVVFGDLHGLNVLVDEDDEVSVIDFEMASTDSAAPRPALGA
                     PGFRAPEGRTGVAIDRYALAALKLWMFLPLNPLLELSPGKLAGFVDIVERRFPLPAGFG
                     DQIRRELLGTEAAVTELDNAVPDWGVVRKGLAEAILCTATPEREDRLFPGDIEQFRVGG
                     TCFAYGAAGVLHALDAAGLGRYPEHERWLVDAVRRTAPARPGFLDGAHGIAHVLENLGH
                     HSDADALLDGAATLVEQTRDHGFGGGLSGIALNLLHFASTRDDRELRERARDLGDRLAD
                     ALRVALPPGSVGRAGLLDGWAGPALLFTHLHDDTGDRGWLELADRALQRDLDECVATDD
                     GALQVRDSGTRTLPYLAVGSAGVALVAEELAARHPGASCLERQPELLRGCLGEFVIHPG
                     LLFGRCGLLAALAAANRRAPDPMWTDAVSRHLTALGWHAIPHGDGGIAMPGNQLLRLSM
                     DLATGGAGVLSAVAATLDGHGRVLPFFGRPNA"
     subregion       1..6203
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="RiPP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6203
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            2603..2743
                     /locus_tag="SACE_4231"
     CDS             2603..2743
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_4231"
                     /db_xref="EnsemblGenomes-Tr:CAM03500"
                     /db_xref="UniProtKB/TrEMBL:A4FHH5"
                     /locus_tag="SACE_4231"
                     /product="hypothetical protein"
                     /protein_id="CAM03500.1"
                     /transl_table=11
                     /translation="MEMVLELQELDAPNELAYGDPSHGGGSNLSLLASCANSTVSLLTC
                     H"
     gene            2839..4497
                     /gene="ramA"
                     /locus_tag="SACE_4232"
     CDS             2839..4497
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_4232"
                     /db_xref="EnsemblGenomes-Tr:CAM03501"
                     /db_xref="GOA:A4FHH6"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A4FHH6"
                     /function="ABC-type multidrug transport system, ATPase and
                     permease components"
                     /gene="ramA"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 304.2; E-value: 3e-92)"
                     /gene_kind="transport"
                     /locus_tag="SACE_4232"
                     /product="putative ABC transporter"
                     /protein_id="CAM03501.1"
                     /transl_table=11
                     /translation="MARAGDRLLRSAVRHDRGTAALLLFTALLAAAASVLLPTALADAV
                     DSVLSGDGASARVLWLVSLGAAQVLAEVAGVALTARLTAAAAARLRALLATALVRSGGR
                     SPVADGDAVSRMTGDCAGAGQIVSVVVQLCTALLLAAGAAVALVLIDWRVALVLLVAVP
                     AAVLLARSHLRHTADDVLAYQEAAGSLGARLLDAVLGLRTIAAAGVAEQESARVLRPLP
                     ELSAAGAGMWRTQARMMWRGGLLLPLVQVAVLCAAGFGVLAGDLSVGDVLAALGYATLA
                     LGIVRQLPQFTALSRARSCADRIAALLDHAPPPRPRVPLPRGSGQVELSGVGVDGALDD
                     IDLVVPGGDVVAVVGRSGSGKSALAEVLGGLREPDRGDALLDGVPVGAVERTAVGYSFE
                     RPALLGESVAAAVAYGSGADDAAVRSACRTADIDDLVTRLPSGYATPLSETPLSGGEAQ
                     RLGLARALARRPRLLVLDDAAAALDTATEARVENAVADEHPGLTRVVVTHRACTARRAD
                     SVVWLEAGCVRAFAPHDALMDEPTYRALFAEEVQP"
     gene            4494..6203
                     /gene="ramB"
                     /locus_tag="SACE_4233"
     CDS             4494..6203
                     /codon_start=1
                     /db_xref="EnsemblGenomes-Gn:SACE_4233"
                     /db_xref="EnsemblGenomes-Tr:CAM03502"
                     /db_xref="GOA:A4FHH7"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR027417"
                     /db_xref="UniProtKB/TrEMBL:A4FHH7"
                     /function="ABC-type bacteriocin/lantibiotic
                     exporters,contain an N-terminal double-glycine peptidase
                     domain"
                     /gene="ramB"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 210.3; E-value:
                     8.6e-64)"
                     /gene_kind="transport"
                     /locus_tag="SACE_4233"
                     /product="putative ABC transporter"
                     /protein_id="CAM03502.1"
                     /transl_table=11
                     /translation="MTVSAQHWRALAGRWRACSVLAAYSLLEALPALLSGGLVQRAVDD
                     GFAAGDPLSGLAWLAAFAAAAVAGAFGVRLVWQRLGTIVEPLRDALVRTVVRGVLHDTA
                     PPRGGPDAAGVARITQHVEVVRDATAGLLVQARGLVVSTAGALVGIASLSGTLAWLAGP
                     PVVIAVAVFLCLLPALARRQRGLALADEATAAATGTVLAGMRDVVACGGQDIAEDSMRT
                     AIRSQAGAAVRMSNAAALRTAVVAVGGFLPVVLVLAAAPAAVAAGELTAGTVLGTLVYL
                     TGTLHPALHGFAATTSTVVVRLLVALNRLSEVRPPEPPRATAVPDGAAVRVRGLTHRWG
                     EHSEPILRDFDMDLDPGQHLAVVGPSGIGKSTLASLLTGTVQPCEGRVLVGGVPIAEID
                     PAHRHRLIAFTPQECYLFAGTARENLALLAPGADDAHLLRAASAVGADALLDRLGGLDA
                     ALGHAGAGLSAGERQLLGLARVFASPARIVVLDEATAHLDGAAEARAERAFAARGGILV
                     VIAHRPASARRAGRVLVMDGRQAVLGEHEQLLVRSRHYADMTQAWAGAGSTR"
ORIGIN
        1 atggatctgc ggtacgaagc tttctgcttc gccgatccgc tcttcttcga cgagcaacgc
       61 cggcactccg gtactcagga cgagtacgcc cgacagctgc ccgagcccgg ggacgactgg
      121 gtgcgaagcg ccctcggaac ctggcacatg ctgcgtccgg cggaggtcgt tctccccgca
      181 cagggctgga aagtgcacgt ctcggccacg ctcggcaacg cggagcgggt gctggccgcg
      241 gtccaccgct actgcctgcg ggaacgcgtc gcgttcaaac acctgcgcag cccccgcgta
      301 ctgctcgcgc gcaacgccaa atacgcgccg cgctcggcga gcgggaagct ggtcaccatt
      361 tatccggtgg acgacgaaca cctggccacc gtgctcaccg aattggcacc gcaattgcgg
      421 ggcgagccgg gcccttacat cctcagcgac ctgcgttatg agcagggccc gctgtacgtg
      481 cgttacggcg gattcgcgga acgctgggtc gagttcgacg ggacccgggt tctcgccatt
      541 gccggcccgg acggcgagct ggttcccgac aagcgcaacc cggggttctc cttgcccgac
      601 tgggtctccc cgccggagtg cctgagcgcg tcgctggccg cccgcaaggg cggcgaccgc
      661 gccgccttcg gctaccgggt cacctcgtcg atgcacttct ccaacggcgg cggggtctac
      721 cgcgccgtgc gcaagtccga cggtgccgag gtcgtgctca aagaagcccg cccgcacgcg
      781 ggactggacc gcgacggcac cgacgccgtg gcccggctgc accgggagca cgaggtgctg
      841 cgcaggctcg acggcatcgg cggtgtcccc gccgtgcacg agctgttcca gctctgggag
      901 cacaccttcc tcgcgatgga cctggttccc ggcacgccgc tgggcacgtg gctggcgcgc
      961 acctacccgc tcacccggca gcaccccacc gagcaggaga tcgccgacta cacccggcgc
     1021 gccctggcac tgctggagcg ggtcgagcgg ctgctggacc gcgtgcacgg gcgcggagtg
     1081 gtcttcggcg acctgcacgg gctgaacgtc ctcgtcgacg aggacgacga ggtctcggtc
     1141 atcgacttcg agatggcctc caccgactcc gccgccccac ggcccgcgct cggcgcaccc
     1201 gggttccggg cgcccgaggg gcgcaccggc gtcgccatcg accggtacgc gctggccgcg
     1261 ctgaagctgt ggatgttcct gccgctcaac ccgctgctgg agctgtcgcc cggcaagctg
     1321 gccgggttcg tcgacatcgt cgaacggcgg ttcccgctgc ccgcaggctt cggcgaccag
     1381 atccgccgcg agctgctcgg gaccgaagcc gcggtgaccg agctcgacaa cgccgtcccg
     1441 gactggggcg tggtgcgcaa gggcttggcc gaggcgatcc tctgcacggc gacgcccgag
     1501 cgcgaggacc ggctgttccc cggcgacatc gagcagttcc gcgtcggcgg cacctgcttc
     1561 gcctacggcg ccgccggtgt cctgcacgcg ctggacgccg ccgggctcgg ccgctacccc
     1621 gagcacgagc gctggctggt cgacgcggtg cggcgcaccg caccggcccg gcccggtttc
     1681 ctcgacggcg cgcacggcat cgcccacgtg ctggagaacc tcggccacca ctccgacgcc
     1741 gacgccctgc tcgacggcgc cgcgacgctg gtcgagcaga cccgcgacca cggattcggc
     1801 ggcgggctgt cggggatcgc gctcaacctg ctgcacttcg cgtccacgag ggacgaccgc
     1861 gagctgcggg agcgcgcccg cgacctgggc gaccggctgg ccgacgcgct gcgcgttgcc
     1921 ctgccgccgg gctcggtggg acgcgccggc ctgctcgacg gctgggccgg cccggcgctg
     1981 ctgttcaccc acctgcacga cgacaccggc gaccgcggct ggctcgagct cgccgaccgc
     2041 gcgctccagc gcgacctcga cgagtgcgtg gccaccgacg acggcgcgtt gcaggtccgc
     2101 gacagcggca cccggacgct gccctacctc gcggtcggca gcgccggagt cgccctggtc
     2161 gccgaggagc tcgccgcgcg ccacccgggt gcgagctgcc tggagcgcca accggagctg
     2221 ctgcgcggct gcctcggcga gttcgtgatc cacccgggcc tgctcttcgg gcgctgcggt
     2281 ctgctcgccg cgctggccgc ggcgaaccgc cgcgcccccg atccgatgtg gaccgacgcg
     2341 gtctcgcggc acctgaccgc gctcggctgg cacgcgatcc cgcacggtga cggcgggatc
     2401 gccatgcccg gcaaccagtt gctgcgcctg tcgatggacc tcgccaccgg cggcgccggc
     2461 gtgctgagcg ccgtcgcggc gacgctcgac ggtcacggcc gcgtgctgcc gttcttcggc
     2521 aggccgaacg cctgaccacc accccgagaa ctccggccgg acctcggccg gtgatcgaga
     2581 acgaccggaa aggaacacca ccatggagat ggttctggag ctgcaggagc tcgacgcccc
     2641 caacgagctg gcctacggcg accccagcca cggcggcggg agcaacctga gcctgctggc
     2701 ctcgtgcgcc aacagcacgg tgagcctcct gacctgccac tgacgcggca cgggtgcgag
     2761 agcggcgcag gacaggtgcg ccgctctcgc accgcaacag tctggcgcgc ggccagcgca
     2821 acgacaagga gcagtcacat ggcccgtgcg ggcgaccgcc tgctgcgctc ggcggtgcgc
     2881 cacgaccgcg gcaccgcggc tctgctgctg ttcaccgccc tgctcgcggc cgccgcgagc
     2941 gtcctcctgc cgaccgccct ggccgacgcc gtcgactccg tgctgtcggg cgacggggcg
     3001 tccgcgcgcg tgctgtggct ggtttcgctg ggcgcggccc aggtgctggc cgaagtcgcc
     3061 ggagtcgccc tcaccgccag gctcaccgcc gctgccgccg cccgcctgcg agcactgctc
     3121 gcgacggcgc tggtccgctc cggtggccga tccccggtcg ccgacggcga cgccgtcagc
     3181 cggatgaccg gcgactgcgc gggtgcgggc cagatcgtct cggtcgtcgt ccagctctgc
     3241 accgcgctgc tgctggcggc gggagccgcc gtggccctgg tgctcatcga ctggcgcgtg
     3301 gccctggtgc tcttggtcgc cgttccggcc gctgtgctgc tcgcgcgctc ccacctgcgg
     3361 cacaccgccg acgacgtgct cgcctaccag gaggcggcgg gctcgctcgg ggcgcggctg
     3421 ctcgacgccg tcctgggact gcgcaccatc gccgcagccg gggtcgccga gcaggagtcc
     3481 gcgcgcgtgc tgcgcccgct gcccgagctg agcgccgccg gtgccggtat gtggcgcacc
     3541 caggcgcgga tgatgtggcg cggcggtctg ctcctgcccc tcgtgcaggt cgccgtgctg
     3601 tgcgcggccg gtttcggcgt cctggccggt gatctcagcg tcggcgacgt gctcgccgcg
     3661 ctcggctacg cgacgctcgc gctcggcatc gtccggcagc tgccgcagtt caccgcgctg
     3721 tcgcgcgcgc ggtcgtgcgc ggaccggatc gcggccctgc tcgaccacgc tccaccaccc
     3781 cgcccgagag tcccgttgcc ccgcggaagc ggacaggtgg aactgagcgg tgtcggggtc
     3841 gacggcgcgt tggacgacat cgacctcgtg gttcccggcg gtgacgtcgt ggccgtcgtc
     3901 ggccgctccg ggtccggcaa gtccgcgctc gccgaagtgc tgggcggcct gcgcgaaccg
     3961 gaccgcggtg acgcgctgct cgacggagtc ccggtcggcg cggtcgaacg caccgccgtc
     4021 ggctactcct tcgaacgtcc cgcgctgctc ggcgagtcgg tcgccgccgc cgtcgcctac
     4081 ggcagcggcg cggacgacgc ggcggtgcgc tcggcgtgcc gcaccgccga catcgacgac
     4141 ctggtgaccc ggctcccctc cggctacgcc acgccgctgt cggagacccc gctctccggt
     4201 ggggaagccc agcggctcgg cctggccaga gcgctcgccc ggcggccgag gctgctcgtg
     4261 ctcgacgacg cggccgccgc gctggacacc gccaccgaag cccgggtcga gaacgccgtc
     4321 gccgacgaac atccggggct gacccgcgtc gtggtcaccc accgggcctg caccgcgcgt
     4381 cgcgcggact cggtggtgtg gctggaggcg ggatgcgtgc gcgccttcgc accgcacgac
     4441 gcgctgatgg acgaacccac ctaccgcgcg cttttcgccg aggaggtcca gccgtgacgg
     4501 tcagcgccca gcactggcgc gcactcgccg ggcgctggcg cgcctgctcg gtgctcgcgg
     4561 cctactcgct gctggaggcg ctgcccgcgt tgctctccgg tggactcgtg cagcgtgccg
     4621 tggacgacgg tttcgccgcc ggggacccgc tgagcggtct ggcctggctg gccgccttcg
     4681 ccgccgcggc ggtggccggg gcgttcggcg tccggctggt ctggcagcgg ctcggcacga
     4741 tcgtcgaacc gctgcgcgac gcgctcgtgc gcaccgtcgt gcggggcgtc ctgcacgaca
     4801 ccgcccctcc gcgcggcggc ccggacgcgg cgggggtcgc ccggatcacc cagcacgtgg
     4861 aggtcgtgcg cgacgccacg gcgggtctgc tggtccaggc gcgcggactc gtggtgagca
     4921 cggccggtgc cctggtgggc atcgcttcgc tgtcggggac gctggcgtgg ctcgccggcc
     4981 ccccggtggt gatcgcggta gcggtgttcc tgtgcctgct gcccgcgctg gcgcgcaggc
     5041 agcgcgggct cgcactcgcc gacgaggcca ccgcggcggc gaccggcacc gtgctggcgg
     5101 gcatgcgcga cgtcgtggcc tgcggcgggc aggacatcgc cgaggactcg atgcggacgg
     5161 cgatccgttc ccaggccggt gccgcggtgc ggatgtccaa cgccgccgcc ctgcgcaccg
     5221 ccgtggtcgc cgtcggcggc ttcctgccgg tcgtgctcgt gctcgccgcc gcgccggcgg
     5281 cggtcgccgc gggcgagctg accgcgggca cggtgctcgg cactctggtg tacctgaccg
     5341 gcaccctgca cccggcgctg cacgggttcg ccgcgaccac gagcacggtc gtggtgcgcc
     5401 tgctcgtcgc gctcaaccga ctcagcgagg tccgcccgcc cgagccgccg cgcgcgaccg
     5461 ccgtgccgga cggagccgcg gtccgcgtgc gcgggttgac gcaccgctgg ggcgagcact
     5521 ccgaaccgat cctgcgcgac ttcgacatgg acctggatcc cggccagcac ctggcggtgg
     5581 tcggccccag cggcatcggc aagtccaccc tcgcgtcgtt gctgaccggc accgtgcagc
     5641 cgtgcgaggg acgagtgctg gtcgggggcg tcccgatcgc cgaaatcgac cccgcgcacc
     5701 gccaccgcct catcgccttc accccgcagg agtgctacct cttcgccggt accgcgcggg
     5761 agaacctggc gttgctggca cccggcgccg acgacgcgca cctgctgcgc gccgcgtccg
     5821 cggtcggcgc cgacgcgctg ctcgacaggc tgggcgggct ggacgccgcg ctcggccacg
     5881 cgggcgcggg actgtcggcc ggggaacgcc agttgctggg gctggcgcgg gttttcgcga
     5941 gcccggcgcg gatcgtcgtg ctggacgagg ccaccgcgca cctagacggt gcggcggaag
     6001 cacgagccga gcgggctttc gccgcccggg gcggcatcct ggtggtcatc gcgcaccggc
     6061 cggcctccgc ccgccgcgcc ggccgggtgc tggtcatgga cggaaggcag gcggtgctcg
     6121 gcgagcacga acagctgctc gtgcgctcgc ggcactatgc cgacatgacc caggcgtggg
     6181 cgggagccgg ctccacgcgg tga
//
