LOCUS       BGC0000588             12519 bp    DNA     linear   BCT 07-JUL-2008
DEFINITION  Escherichia coli putative resolvase, colicin M resistance protein
            (cmi), and microcin V immunity protein (cvi) genes, complete cds;
            cvaC' gene, complete sequence; and microcin L immunity protein
            (mclI), microcin L precursor (mclC), putative microcin L transport
            protein (mclB), putative microcin L transport protein (mclA), stable
            inheritance protein PemI (pemI), stable inheritance protein PemK
            (pemK), putative plasmid stable inheritance protein (stbB), and
            putative plasmid segregation protein ParM genes, complete cds.
ACCESSION   BGC0000588
VERSION     BGC0000588
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
COMMENT     On Jul 3, 2008 this sequence version replaced AY237108.1.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 19:57:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..12519
                     /db_xref="taxon:562"
                     /isolate="LR05"
                     /mol_type="genomic DNA"
                     /organism="Escherichia coli"
     subregion       1..12519
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000588"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12519
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             2440..3222
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 95.4; E-value: 8.8e-29)"
                     /gene_kind="other"
                     /note="similar to resolvase (protein D) in P18021"
                     /product="putative resolvase"
                     /protein_id="ACF22181.1"
                     /transl_table=11
                     /translation="MQHLPAPIHHARDAAQLPVAIDYPAALALRQMSMVHDELPKYLLA
                     PEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPFVQLATLKQRTE
                     KAARTAGRMPAGQQTHRLVPLSDTWYVSQLQTMVATLKIPMERRNKRTGRTEKARIWEV
                     TDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSI
                     SSTEVYTKVFALDVAARHRVQFLMPESDAVTMLKNRQA"
     gene            3372..3752
                     /gene="cmi"
     CDS             3372..3752
                     /codon_start=1
                     /gene="cmi"
                     /product="colicin M resistance protein"
                     /protein_id="ACF22182.1"
                     /transl_table=11
                     /translation="MNDRSCGDFMKVISMKFIFILTIIALAAVFFWSEDKGPACYQFSD
                     EQARTFVKNDYLQRMKRWDNDVQLLGTEIPKITWEKIERSLTDVEDEKTLLVPFKAEGP
                     EGKRMYYGMYHCEEGYVEYAND"
     misc_feature    3399..3401
                     /gene="cmi"
                     /note="possible alternate site of translation initiation"
     gene            4539..4775
                     /gene="cvi"
     CDS             4539..4775
                     /codon_start=1
                     /gene="cvi"
                     /note="microcin V (ColV) immunity protein"
                     /product="microcin V immunity protein"
                     /protein_id="AAP03988.1"
                     /transl_table=11
                     /translation="MDRKRTKLELLFAFIINATAIYIALAIYDCVFREKDFLSMHTFCF
                     SALMSAICYFVGDNYYSISDKIKRRSYENSDSK"
     gene            4753..4836
                     /gene="cvaC'"
                     /note="similar to microcin V (ColV) leader peptide"
     gene            4833..4988
                     /gene="mclI"
     CDS             4833..4988
                     /codon_start=1
                     /gene="mclI"
                     /product="microcin L immunity protein"
                     /protein_id="ACF22183.1"
                     /transl_table=11
                     /translation="MKTWQVFFIILPISIIISLIVKQLNSSNLVQSVVSGIAIALMISI
                     FFNRGK"
     gene            4992..5309
                     /gene="mclC"
     CDS             4992..5309
                     /codon_start=1
                     /gene="mclC"
                     /note="antibiotic"
                     /product="microcin L precursor"
                     /protein_id="AAP03989.1"
                     /transl_table=11
                     /translation="MREITLNEMNNVSGAGDVNWVDVGKTVATNGAGVIGGAFGAGLCG
                     PVCAGAFAVGSSAAVAALYDAAGNSNSAKQKPEGLPPEAWNYAEGRMCNWSPNNLSDVC
                     L"
     gene            complement(5496..7592)
                     /gene="mclB"
     CDS             complement(5496..7592)
                     /codon_start=1
                     /gene="mclB"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 239.4; E-value:
                     1.3e-72)"
                     /gene_kind="transport"
                     /note="similar to MchF, CvaB and MceG, the ABC transporter
                     proteins of microcins H47, V and E492"
                     /product="putative microcin L transport protein"
                     /protein_id="AAP03990.1"
                     /transl_table=11
                     /translation="MTNGNFRQIINQLDMRWRRRVPVIHQTETAECGLACLAMICGHFG
                     KNIDLISLRRKFNLSARGANLAGINGIAEQLGMVTRALSLELDELGALKMPCILHWDFS
                     HFVVLVSVKRNRYVLHDPARGRRYLGREEMSRYFTGIALEVWPGSEFQAETQQTRISLR
                     SLINSIYGIKRTLAKIFCLSVVIEAINLVMPVGTQLVMDHAIPAGDRGLLTLISAGLMF
                     FILLRAAVSMLRAWSSLVMSTLINVQWQSGLFDHLLRLPLAFFERRKLGDIQSRFDSLD
                     TLRATFTTSVIGLIMDSIMVVGVFVMMLLYGGYLTWIVLCFTTIYIFIRLVTYGNYRQI
                     SEECLVREARAASYFMETLYGIATVKIQGMVGIRGAYWLNMKIDAINSGIKLTRMDLLF
                     GGINTFVTACDQVVILWLGAGLVIDNQMTIGMFVAFSSFRGQFSERVTSLTSFLLQLKI
                     MSLHNERIADIALHEKEEKKHEIEIVAHMGPISLETNDLSYRYDSQSAPIFSALSLSVA
                     PGESVAITGASGAGKTTLMKVLCGLFEPDSGRVLINGIDIRQMGINNYHRMIACVMQDD
                     RLFSGSIRENICGFAEEMDEEWMVECARASHIHDVIMNMPMGYETLIGELGEGLSGGQK
                     QRIFIARALYRKPGILFMDEATSALDSESEHFVNVAIKNMNITRVIIAHRETTLKTVDR
                     VISI"
     gene            complement(7585..8826)
                     /gene="mclA"
     CDS             complement(7585..8826)
                     /codon_start=1
                     /gene="mclA"
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 71.9; E-value:
                     7.4e-22)"
                     /gene_kind="transport"
                     /note="similar to MchE, CvaA and MceH, the membrane fusion
                     proteins of microcins H47, V and E492 ABC transporters"
                     /product="putative microcin L transport protein"
                     /protein_id="AAP03991.2"
                     /transl_table=11
                     /translation="MKWQGRAILLPGIPLWLIMLGSIVFITAFLMFIIVGTYSRRVNVS
                     GEVTTWPRAVNIYSGVQGFVVRQFVHEGQLIKKGDPVYLIDVSKSTRSGIVTDNHRRDI
                     ENQLVRVDNIISRLEESKKITLDTLEKQRLQYTDAFRRSSDIIQRAEEGIKIMKNNMEN
                     YRNYQAKGLINKDQLTNQVALYYQQQNNLLSLSGQNEQNALQITTLESQIQTQAADFDN
                     RIYQMELQRYELQKELVNTDVEGEIIIRALTDGKVDSLSVTVGQMVNTGDSLLQVIPEN
                     IENYYLILWVPNDAVPYISAGDKVNIRYEAFPAEKFGQFSATVKTISRTPASTQEMLTY
                     KGAPQNTPGASVPWYKVIAMPEKQIIRYDEKYLPLENGMKAESTLFLEKRRIYQWMLSP
                     FYDMKHSATGPLND"
     gene            10233..10490
                     /gene="pemI"
     CDS             10233..10490
                     /codon_start=1
                     /gene="pemI"
                     /note="similar to to stable inheritance protein PemI in
                     NP_943201"
                     /product="stable inheritance protein PemI"
                     /protein_id="ACF22184.1"
                     /transl_table=11
                     /translation="MHTTRLKKVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIVE
                     PHRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            10423..10824
                     /gene="pemK"
     CDS             10423..10824
                     /codon_start=1
                     /gene="pemK"
                     /note="similar to stable inheritance protein PemK in
                     NP_862963"
                     /product="stable inheritance protein PemK"
                     /protein_id="ACF22185.1"
                     /transl_table=11
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQGT
                     RPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRTID
                     MKARGGKRLERVPETIMNEVLGRLSTILT"
     gene            complement(10939..11334)
                     /gene="stbB"
     CDS             complement(10939..11334)
                     /codon_start=1
                     /gene="stbB"
                     /note="similar to plasmid stable inheritance protein in
                     YP_406075"
                     /product="putative plasmid stable inheritance protein"
                     /protein_id="ACF22186.1"
                     /transl_table=11
                     /translation="MESSDPKKRKKVVAYLHPTLYPQDSLTQQTIDSLPIQMRGDFYRQ
                     SLICGAALYSVDPRLLTLISGFFSEKITAENLVKLIEQTTGYTSTSIDINVLKNIIEAS
                     SENKSESIASKDDFEEQTRRNLSMLKK"
     CDS             complement(11334..12338)
                     /codon_start=1
                     /product="putative plasmid segregation protein ParM"
                     /protein_id="ACF22187.1"
                     /transl_table=11
                     /translation="MLNLRQTQTQNEAKRMLKVSCDDGSTNVKLAWLEDGEVRTSLSGN
                     SFKEGWNPGLFNAGKVYNYVVDGKKYTYDLGSTAVIGTTHVSYQYSTTNLLAIHHALLT
                     SGLQPQDVELTVTLPVTEFFDNDNQPNEERIERKKANVLREISLNKGETFKIKKVNVMP
                     ESLPAAFESLKKDKVNKLERSLIIDLGGTTLDCGLILGAFEGISEIRGYSEIGTSRITH
                     TVMNALTKASTPCNYFIADELIKNRHDNEYLQTLINDVAEIKNITHVIDSEVKSLAESI
                     RQEISTFSGMNRIYLTGGGAELIYPHIKQYFPNLKVNKVDEPQFALVKAMVHA"
     misc_feature    complement(12291..12293)
                     /note="possible alternate site of translation initiation"
ORIGIN
        1 attggcccgt catgaaccgt ctggttctgg ggaaaattac aggagacttc aattgaggcg
       61 ggcacgcgag ccgcgccacg atatcggtgc cggatcccgg ggcaggctct ctataaaggt
      121 gtaaagtgcc tgggcggact cccgtcgctt cagggcatta atcgccttaa gctgaagaag
      181 gacctttctg tcaaactggt acagttcaaa aaggcgggga tcagcctgta actgaacaat
      241 atcccgttca gtatcgtagt aggctgactg taccagatgg gtgatgtatt cccgggtgtg
      301 cctctcatcg gtgcgggaaa aggagatcac ggtaccggca atgcgtttca gggaagggct
      361 gatgcgctca cgcagcctgc gggatgactg gcttgaaggt ataccacaca gttttgcaaa
      421 ctcgacaaaa ggcagttcaa ctttgtcacc aatcacgtta tggcgggcaa aggaatgaat
      481 gatccccacc aggtcttgaa atcgttatcc atatccagcc gggggccggt gatctcaacc
      541 ttatcgaatc cttctgcacg ggccagggaa agacgcgtca gctcttccgt ggcatcggtg
      601 cgtgacagtg tatttttttt actgttcttc agtgatttaa gggtcggtac aaatacgccc
      661 agacgcatca gcgccacagg ctgtacggtg ttgttattgt ttggtgtcag tgtcaccagc
      721 tcaccggacg acttatccac ctcgccgaac agttttttga tgtctgaatt ttcgctttcc
      781 agaaagcctc ctgcctgtgg acagtaaaag aataaacagc aaatcgtgtg tcagaggccc
      841 gctaactgac tgaagaaaaa cctgcagcct gtatttaaca actgagtctg gcgtactgac
      901 catagtttat gtcattaact tacttcagta tatggattac tgaatacagc ttatcattag
      961 catgttacag tttatcagta acatgccaca gcttatgtga tcgtggtccc ggcccatgag
     1021 tgacaaggtt tacagagata tggggatctt taatggatcc tttgttgatc attcatggat
     1081 ctgtttactg gatcgaacct ctggatatgt ggataaatca tcccagggga aacagcatac
     1141 acaacctctt ataagggctt cagggcgtac ctgcgcactg taactacaga tacattgcgc
     1201 ttcctcgccg gttcgcgggc ttcgcccggt caccggtctg cggcgagcac tgttttttct
     1261 gaagtctgtc tttacaggta atttttgacg gaatctgcag tactgaaccg ccccggaaat
     1321 cctggagact aaacttcctg agaaagatgt aaacaggatg actaaaaata ctcgtttttc
     1381 ccccgaagtc cgtcaacggg cagttcgtat ggttctggaa agccagggcg aatatgactc
     1441 acaaggggcg gcaatttgtt ccattgctcc aaagattggc tgtacgccag agaccctgcg
     1501 tgtctgggtt cgccagcatg agcgggatac cgggggcggt gatggtgggc tcaccaccgc
     1561 tgaacgtcag cgtctgaaag agctggaacg cgaaaatcgt gaactgcgcc gcagtaacga
     1621 tatccttcgc caggcttccg cttattttgc ggttacggat cttcctcccc ctccgcacag
     1681 cgccacaccc tgtaagcaca acatgtggtg ccggattcag ctgctgatga cactatatgt
     1741 tgtgtcatct ccctgacctg tgatgcgccg cgcaggggcg gaaaacagcg atatgattat
     1801 ttcctcagcg tgatacactt ccggaaagtt gtgatattca ggaaagtcgg atctgacgga
     1861 aacggctctc cagtaattta acggcgtggt tatatggatg cttgttatca tggtgatgat
     1921 gataacggca tgatgttatc agacggcgtg acggtaaggg cagtgatgat ggatgacgtt
     1981 atcgcatgac cgtccctgcc cggaaaagaa aaaaggagtc acccatgttt tttattgaga
     2041 atgaaggtca ggctgtcgcc agaacggatt actggcagtc tgtacaggcg caggccggat
     2101 atgtctacct cagctggaat gccggcgcag ccaggctgct tgtcccggat gcggcaaaac
     2161 atttactcag ggagatgcgg ggggctgagt acgtcatcat cagtaaggga gcactgcatg
     2221 gccgcgatgc gctggaactg gtatttgaag acggcagcga tgcgccgttt gtgatccaca
     2281 tgctgagtga gcagtgcgat cgcctgctcc ccgaaaacaa ccagggaggg ggttttgttg
     2341 tcaccgtctg gacgcgtggc ggtaaccagc tccgttatcc gggaaagtac cgtgttgtgg
     2401 aaaacctgcc cgacgtttcc ccgtggagtg aacactgata tgcagcacct gccggcaccg
     2461 atccaccatg cccgggatgc cgctcagctt cctgttgcca tcgattatcc ggcagcgctg
     2521 gcactccgcc agatgtcgat ggttcatgat gaactgccaa aatacctgct ggcccctgaa
     2581 gtgagcgccc tgctccatta cgtcccggat ctgcgccgca agatgctgct ggccacactg
     2641 tggaacaccg gtgcgcgcat taatgaagca ctggcgctga cgcgggggga tttttcgctc
     2701 acgcctccgt atccgtttgt gcagctggcc actctgaagc agcggacaga aaaagccgcc
     2761 aggacggcag gaagaatgcc cgccggtcag cagactcacc ggctggttcc gctttccgac
     2821 acctggtacg tcagccagct gcagacgatg gtggccacac tgaaaatccc catggaacgg
     2881 cgtaataaac gaacaggcag gacagagaaa gcgcggatct gggaagtgac ggacagaacg
     2941 gtcaggacct ggattgggga ggcggttgcc gccgctgccg ctgatggtgt gacgttctct
     3001 gtcccggtca cgccacatac gttccgccat tcctatgcga tgcacatgct gtatgccggt
     3061 ataccgctga aggtcctgca gagcctgatg gggcataagt ccatcagctc aacggaggtc
     3121 tacacgaagg tgtttgcact ggatgtggct gcacggcacc gggtgcagtt tttgatgcct
     3181 gagtccgatg ctgtcacaat gctgaaaaac aggcaggcat aaatcataag tcataattat
     3241 gaattgtgat ttattctgta aaaaaagaga ccactgcaat atgtgatctc ttgtattatt
     3301 tcataattgt taaagccact tcacagtatg ctcacattgt acggatatat tcgtaatgtt
     3361 ttttatatcg aatgaacgac agaagttgtg gagattttat gaaagtaatt agcatgaaat
     3421 ttatttttat tttaacgatt attgctcttg ctgctgtttt tttctggtct gaagataaag
     3481 gtccggcatg ctatcagttc agcgatgaac aggccagaac atttgtaaaa aatgattacc
     3541 tgcaaagaat gaaacgctgg gacaacgatg tacaacttct tggtacagaa atcccgaaaa
     3601 ttacatggga aaagattgaa agaagtttaa cagatgttga agatgaaaaa acacttcttg
     3661 tcccatttaa agctgaaggt ccggagggta agagaatgta ttatggcatg taccattgtg
     3721 aggagggata tgttgaatat gcgaatgact aatacactgt tataaaggct gcataaaaag
     3781 gccggaatcc cggcccttat attatcgctt accactttct ttaatgtgaa tttcaccagg
     3841 aagcagtatc tggtactctt taccagaaca catcgccccg agccttgtga gcgactctcc
     3901 gatgacgcca cggtgagtgc tggcgttaaa atcgtattta tcatcataat gacagagcgc
     3961 gagcaaatgc ctttattgaa atcgccagaa tgatgttcag cggcttcgcc caggtatttt
     4021 ctttctcccc ttctatgccc tgccggacat tgtataaatg tagggggcag tttggaattt
     4081 ggaaaataaa ggggtcaact cacgaaacgg aaaaatcgta cgctaagagc gtaaggtgtc
     4141 aggttgaagt cacagactcc gcgtcaggag tgtccagaaa attcgaaata gcccctattt
     4201 tttagtcaaa tgactttcag gaatcgccag aatggcggga caacagcggt tttggtgtcc
     4261 gaactcgtac aattctgaac atctacgcaa gggaatgtac ggaagtaagc caaatggtta
     4321 tcggacggta ggaacatttc gtacatcctt tacgtttagt gagttagctg gcttggatgg
     4381 atgtaaccac ttgttcaact caattctctt gacgtgggaa actccgtttt ccaggcggac
     4441 cccttatagg ggggtgaggg ctcccctacc cttcactctt gactatgtaa acgataatca
     4501 ttatcgttag tgtttgtatg gtaatgggat agaaagtaat ggatagaaaa agaacaaaat
     4561 tagagttgtt atttgcattt ataataaatg ccaccgcaat atatattgca ttagctatat
     4621 atgattgtgt ttttagagaa aaggattttt tatccatgca tacattttgc ttctctgcat
     4681 taatgtctgc aatatgttac tttgttggtg ataattatta ttcaatatcc gataagataa
     4741 aaaggagatc atatgagaac tctgactcta aatgaattag attctgtttc tggaggtgtt
     4801 ggcgttacta taactttagc gcaggaatat agatgaaaac gtggcaagta ttttttatta
     4861 tattacccat aagcattatt attagtctta ttgttaaaca actaaattct agcaaccttg
     4921 ttcaatctgt tgttagcggt atcgccattg cattaatgat atctattttt tttaataggg
     4981 gtaaatgata tatgagagaa ataacgttaa atgaaatgaa taatgtctct ggtgctggtg
     5041 atgtcaattg ggttgatgtc gggaaaactg tagcaacaaa cggtgcagga gtgattggcg
     5101 gtgcattcgg agctggtctg tgcggccctg tttgtgctgg tgccttcgct gttggatctt
     5161 ctgccgctgt tgctgctttg tatgatgcag caggaaattc caactcagcg aaacaaaaac
     5221 cagaaggact acctccagaa gcatggaact acgctgaagg tagaatgtgt aattggagtc
     5281 caaataatct tagtgatgtt tgtttataaa tagtattttt taatatagga aagaactgtt
     5341 attggacaat ccacacagaa tgatacatat gcttcctggt gggttgtcta tcttccattc
     5401 ctcctccaac tgacaactga acataacgag gaattatcac aggaagatat attcctcata
     5461 cagttgcaat tcctctatgg ttatgtcagt agattttaaa tggaaataac tctgtcaaca
     5521 gttttcaacg ttgtttctct gtgtgcaata attaccctag ttatattcat gttttttatg
     5581 gcaacattca cgaaatgttc actctctgaa tcaagagcac tggttgcctc atccataaat
     5641 aatattcctg gtttccggta taaggctcgt gcaataaata tacgctgttt ttgaccgcca
     5701 gaaagacctt ccccaagttc acctattaat gtttcatatc ccattggcat attcattata
     5761 acatcatgaa tatgacttgc tctggcacat tctaccatcc actcttcatc catttcctct
     5821 gcaaaaccac agatattttc acgaattgag cctgaaaata gccggtcatc ctgcataaca
     5881 caggctatca tccggtgata attatttatt cccatttggc gtatatctat accatttatc
     5941 agtaccctcc cgctatcagg ttcaaatagt ccacatagta ctttcattaa tgtggttttt
     6001 cccgcaccgg aagcaccagt tatagccaca ctttcccccg gagctactga taaactcaga
     6061 gcactgaata tcggagctga ctgactgtca taccggtagc ttaaatcatt ggtttccagg
     6121 gatattggcc ccatatgagc aacgatttca atttcatgtt tcttttcctc cttttcatgt
     6181 aatgcaatat ctgcaatgcg ctcattgtgt agactcatta tttttagctg aagaagaaaa
     6241 ctggtcagag aggtaactct ttccgaaaac tgcccacgaa aagaactaaa cgctacaaac
     6301 attcctattg tcatctgatt atcgatcaca aggccagctc ccagccataa aattacaacc
     6361 tgatcacagg cggtaacaaa ggtatttatt cctccgaaga gcaaatccat cctggttagc
     6421 ttaatacccg aatttatcgc atctattttc atattaagcc agtatgctcc ccgaattccg
     6481 accatcccct ggatttttac cgtggcaata ccatataatg tttccataaa ataggaggcg
     6541 gcacgggcct ccctgacaag acattcttct gatatctgtc ggtaattgcc gtatgtcacc
     6601 agacgaataa aaatgtaaat tgtggtaaag cagagaacta tccaggtgag atatcctccg
     6661 tataacagca tcatcacaaa aacaccgaca accataatgc tgtccattat taacccgatc
     6721 acactggtgg taaatgtggc cctcaatgtg tcaagggagt caaaacgtga ctggatatca
     6781 cctaattttc ggcgttcaaa aaacgccagc ggtagtctga gaagatgatc gaacagcccc
     6841 gactgccact gtacattgat gagcgtgctc ataaccagtg aggaccatgc acgcagcata
     6901 ctcaccgcgg ccctgagcaa tataaagaac atcaggccag cagaaataag cgttagcagc
     6961 cctctgtccc ccgccggaat cgcatgatcc ataaccagct gagttcccac cggcattacc
     7021 agattgattg cttcaattac aactgacaga cagaaaattt tcgccagtgt tcttttaata
     7081 ccgtaaatac tgttaatcag tgaacggaga cttatgcggg tctgctgggt ttccgcctgg
     7141 aattcacttc cgggccagac ctcaagtgca atacccgtaa aataccggct catttcctcc
     7201 cgaccgagat atcttctgcc tctggccgga tcatgcagta cataacggtt acgctttacg
     7261 ctgaccagca cgacgaagtg actgaaatcc cagtggagaa tacacggcat tttgagggca
     7321 ccaagttcat ccagctccag tgaaagagcc cgggtgacca tccccagctg ctctgctatt
     7381 ccattgattc ctgcaaggtt tgctccacgg gccgagagat taaacttccg gcgaagagat
     7441 atcaggtcaa tattcttacc aaaatgaccg catatcattg ccaggcaggc cagtccacat
     7501 tcagcggtct ccgtctgatg aataaccgga acacgacgtc gccagcgcat atcaagctga
     7561 tttataattt gtctgaaatt cccgttagtc attgagcggt cctgttgcac tgtgtttcat
     7621 gtcatagaaa ggagaaagca tccactggta aatacgcctt ttttccagaa atagtgtact
     7681 ttcggctttc attccatttt ccagagggag gtatttttcg tcatatctga taatctgctt
     7741 ttcaggcatc gcaatgactt tataccaggg aacagaggcg cccggcgtat tctgtggtgc
     7801 tcccttatag gtcaacattt cctgtgttga cgcaggagtc ctggatatag ttttaaccgt
     7861 agcagagaac tgcccaaatt tttctgccgg aaaggcttca taacgaatat tcactttgtc
     7921 accagccgaa atataaggaa cagcatcatt cgggacccag agaataagat aataattttc
     7981 aatgttctca ggaataacct gcagaaggct gtctccggta ttgaccattt gcccgacagt
     8041 gacactcagg gagtcaactt tcccgtcagt caacgcccgg ataatgattt cgccctccac
     8101 atcagtgtta accagttctt tctgtaactc gtaccgttgc agttccatct ggtagatacg
     8161 gttatcaaaa tctgcagcct gagtctgaat ctgactctcc agagtggtta tctgcagggc
     8221 attctgttcg ttctgtccgc tcaggctgag aagattgttt tgttgctgat aatataatgc
     8281 cacctggtta gttaactgat ctttattaat cagccctttt gcctgatagt ttctgtaatt
     8341 ctccatattg tttttcatta tttttatccc ttcctctgca cgctgtataa tatctgatga
     8401 gcgacgaaac gcatctgtgt attgcagacg ttgtttttcc agggtatcca gcgttatttt
     8461 tttactttct tccagacggg aaataatgtt gtccacacga accagctggt tttctatatc
     8521 ccgacgatga ttatcagtga caataccact acgtgtactt ttactgacgt caatcagata
     8581 aacaggatcc ccttttttta tcaactgtcc ttcatgaaca aactgcctga caacaaatcc
     8641 ctgtacacct gaatatatat tgacagctct tggccaggtt gtgacctcac cactgacatt
     8701 aacacggcgg ctataggtac caacaatgat gaacatcaga aatgccgtaa taaacacaat
     8761 gcttcccagc atgattaacc acagtggtat tccgggaagt aatattgccc gtccctgcca
     8821 cttcattttt ctgttttcta aagcatcctg gcgaaacaaa taatgtctcc ttgcatacta
     8881 ttagtttgtt gtttatctgg attaatgatg gaaaataaat cgaaaatttg cattatatgt
     8941 ttcaaggaaa atcatataaa cataggagag ttatcaggat aaataatcat ataatgctga
     9001 gaacaatatg ataaacaata gtctttttat ttatgatgaa agaatgtcat tatttattaa
     9061 atgacaataa tctaactgat ttaggttatt gtcagaaaat attaaagtaa cataactcat
     9121 tcatctattt cctagtttct ctgtatatta aaagagaatg gtaatcatta tcatgttaag
     9181 gtgtcatatc gtttacataa agtcaagata tatcagtgtg gcaagcctgg caggattctc
     9241 tagggaaggg caggcatact cagtgcatag ctgatgcacg gatgacggca gggggaggag
     9301 gctggtgact ttcggacgac tgtagcggct tacatcgggc ttcggcggta tcatatgaaa
     9361 cagcggagtg ccgccttcca tgccgctggc gcggcatatc ctggtgacga tatctgaatt
     9421 gttatacatg tgtatatatg tagtaatgac aaaaatagga caagttaaaa atttacagga
     9481 gatacaatga ttcagacacg taatcaatat ctgcagttta tgctggttat gctggctgca
     9541 tggggcatta gctggggagc cagatttgtc atggagcagg ccgttctgct ttatgggcca
     9601 ggaaaaaacg atttgttctt cagtcatggt gctgttctga tgtacctgct gtgtgttttc
     9661 ctggtatacc gccgttggat agctccgcta ccggtcgttg gtcagctgcg caacgttggc
     9721 gtaccgtggc tggtcggtgc gatggccgtg gtgtatatcg gtgtatttct gctcggtaag
     9781 gtgctggctc tgcctgctga gccatttatg acgaaacttt ttgccgataa gtctatacct
     9841 gacgtgagcc tgacgttgct gaccatcttt atccttgccc cgttgaatga ggaaacgctg
     9901 ttccggggga ttatgctgaa cgtcttccgt tcacggtact gctggacgat gtggctgggg
     9961 gcgctgataa cgtcgttgtt gttcgtcgcc gcgcatagcc agtataagaa cctgctgaca
    10021 ctggcagagc tgttcctggt gggggtgatt acatcagcgg ccaggatcag aagtggtggc
    10081 ctgctgctgc cggtattgct gcatatggaa gcaaccacgc tgggtttact gtttggttga
    10141 aagttatatt tttattaaac attgcgcgtt aaagcctggt gtgttttttt agtggatgtt
    10201 atatttaaat ataactttta tggaggtgaa gaatgcatac cacccgactg aagaaggttg
    10261 gcggctcagt tatgctgacc gttccaccgg cactgctgaa tgcgctgtct ctgggtacag
    10321 ataatgaagt tggcatggtc attgataatg gccggctgat tgttgagccg cacagacgcc
    10381 cgcaatattc actggctgag ctactggcac agtgtgatcc gaatgctgaa atatcagctg
    10441 aagaacgaga atggctggat gcaccggcga ctggtcagga ggaaatctga catggaaaga
    10501 ggggaaatct ggcttgtctc gcttgatcct accgcaggtc atgagcagca gggaacgcgg
    10561 ccggtgctga ttgtcacacc ggcggccttt aatcgcgtga cccgactgcc tgttgttgtg
    10621 cccgtaacca gcggaggcaa ttttgcccgc actgccggct ttgcggtgtc gctggatggt
    10681 gttggcatac gtaccacagg tgttgtgcgt tgcgatcaac cccggacaat tgatatgaaa
    10741 gcccggggcg gaaaacgact cgaacgggtt ccagagacta tcatgaacga agttcttggc
    10801 cgtctgtcca ctattctaac ttgaacatgg ggtttgaggg gcaaccggac gaaaacgttc
    10861 gatttagggc actaaaaccg ctgctggtcc ctcattataa aagaagagca ggtaataact
    10921 gaacctgctc ttcttttatt atttttttaa catagacaga ttgcgtctgg tttgttcttc
    10981 gaaatcatct tttgaagcga tgctctctga tttgttttct gaagatgcct ctataatgtt
    11041 ttttaacaca tttatatcaa ttgatgtgga tgtgtatcct gttgtttgct ctataagttt
    11101 taccagattt tctgcagtga ttttctcact gaaaaaacca ctgattagcg ttaacagtcg
    11161 ggggtcaaca gaataaagag ctgctccgca aataagagat tgtctgtaga agtctcctcg
    11221 catttgtatc gggagagagt ctattgtttg ttgtgtcagg ctgtcctgcg ggtaaagtgt
    11281 cgggtgcagg tatgccacaa ctttctttct ttttttcgga tcactgcttt ccattacgcg
    11341 tgcaccattg ctttcaccaa tgcaaactga ggttcatcta ccttgttcac tttcagattc
    11401 gggaaatatt gctttatgtg agggtaaata agctcagctc ccccgcctgt gaggtagatt
    11461 cggttcattc ctgagaatgt tgaaatttcc tgcctgatgc tttctgccag agatttcacc
    11521 tcactgtcta ttacatgagt aatatttttt atttcggcta catcatttat taatgtctgg
    11581 agatattcat tatcatgcct gttttttatt aactcatcag caataaaata attgcagggt
    11641 gtggaggctt ttgttagtgc attcatgacg gtatgagtta tgcgggatgt cccgatttct
    11701 gaatagccac ggatttcaga aatgccttca aatgcaccga gaattaaacc acaatccaga
    11761 gtggttcctc caagatcgat aatcaggctg cgttcaagtt tgtttacttt atcttttttt
    11821 agtgattcaa atgcagctgg caaagattca ggcattacat taactttttt aattttaaat
    11881 gtttcccctt tattcagaga tatctcacgg agaacatttg ccttttttct ttctattctt
    11941 tcttcatttg gttgattgtc attatcaaag aattcggtta caggtaatgt cactgtcagt
    12001 tctacatcct gtggctgaag gccggatgtc agcagtgcat gatgtatggc aagcagattg
    12061 gtggtgctgt attgataact gacatgtgtt gtacctatga cagcagtgct gcccaaatca
    12121 taggtgtatt tttttccatc cacgacgtaa ttgtaaactt tgccggcatt aaacagtccc
    12181 gggttccagc cttctttaaa actgtttcct gacagactgg ttcttacctc gccatcttca
    12241 agccaggcta gttttacgtt agttgaacca tcatcgcatg atacttttag cattcttttt
    12301 gcctcgtttt gagtttgtgt ttgtctcaaa ttgagcatct tttatgtcga tgcatctttt
    12361 tgagttttta ttatttctta ttgtgtctca ttttgggtta atgtcaagta acgtggctct
    12421 tttagagtct ccttgtgttc ttgctgtgac tcaatttggg ttgttattgg tttctcattt
    12481 tgcgtcacaa actgagacga aaactactta accaggccg
//
