LOCUS       BGC0000674              4991 bp    DNA     linear   CON 26-JUL-2016
DEFINITION  Streptomyces clavuligerus ATCC 27064 supercont1.14 genomic scaffold,
            whole genome shotgun sequence.
ACCESSION   BGC0000674
VERSION     BGC0000674
KEYWORDS    .
SOURCE      Streptomyces clavuligerus
  ORGANISM  Streptomyces clavuligerus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     The CDS were annotated to begin and end with complete codons.
            Consequently, incomplete CDSs were not extended to the ends of the
            nucleotide sequences.
            Annotation was added to the scaffolds in August 2008.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:14:02
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 74961
            Orig. end    :: 79952
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(1..1347)
                     /locus_tag="SSCG_02149"
     CDS             complement(1..1347)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 378.8; E-value:
                     6.3e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SSCG_02149"
                     /product="cytochrome P450 hydroxylase"
                     /protein_id="EDY49121.1"
                     /sec_met_domain="p450 (E-value: 2.8e-65, bitscore: 208.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPPGHTARPIPLAPGCLPFLGHAVRLIGKPLAFLDEQRGRGDV
                     VEFRIGRQPAYILNHPDLVQSLLTGSRRRFDRGEIFAIASPLFGNGVAVANGDHHRDRR
                     RAVQPLLSHSRLETYLESMAELAAARADGWSDGRRIDLNAEMADVTMNVVAATVFGQSL
                     PAGFGSVIHHQLPLVVAGLARRAYGPAAVLLDRVPNPERTKYRSALTRIHDVVDTLIAA
                     NRDTPTMTALSEGIDERQLHDDVTSLLIGGSHTSGAAASWLFILLSRHPEARRRLHQEV
                     DRVLGGRSATPADLPALVHTRRVVQETLRLYPPVWLFPRRAADDLRLDGYPIMRGTQLF
                     YSPYALHRDPRWYFRPDTFEPDRWDPDRHEQPPRGAYIPFAAGVHGCPGGDFALAELTL
                     LAATLTAKWNLDLAPGSRPRPVAAATLGPEPVTMTVSRRSRPADSGDGS"
     subregion       1..4991
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Terpene"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4991
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1349..2332)
                     /locus_tag="SSCG_02150"
     CDS             complement(1349..2332)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Terpene synthase/cyclase metal-binding domain
                     protein (Score: 236.4; E-value: 8.5e-72)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SSCG_02150"
                     /product="terpene synthase"
                     /protein_id="EDY49122.1"
                     /sec_met_domain="Terpene_synth_C (E-value: 4.2e-19,
                     bitscore: 57.1, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRPVEGSAIWDVLSPHSPHAAAADGKTLVWVEAGELCGHDTAE
                     SANLARIRPGLLAAFCHPKATEDDLTLITKWMAWLFLLDDRIDESDLGRDADLLDGHLQ
                     DLQGVALGIRTASGPMSRALEEIITQASAGMGDAWQLRFRRNISDYLLACVWQAAHRQA
                     GEFPDPEVFPHWRRAFGAIMPSFDLIERTDGGALPSCVYYSRPYQSLLTAAADLVCWTN
                     DLMTVDKEAAHGDLHNLVLVTEHDRHQDRRTASAAVSAACEQRMRAHTSARRDLTGLTA
                     ALGLPDTVRTHADDCAASLLVWVRGHLEWGLETPRYRPGTTGTGTD"
     gene            complement(2313..3170)
                     /locus_tag="SSCG_02151"
     CDS             complement(2313..3170)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 71.5; E-value:
                     1.3e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SSCG_02151"
                     /product="methyltransferase type 12"
                     /protein_id="EDY49123.1"
                     /transl_table=11
                     /translation="MRRRCSADSDPPDYGDEIFASGHPAQMDRLRALAAVCDPVTKASL
                     SEWALPPGARCLEIGAGAGTVALWLAGRCTGGEVTATDTDIRFMAGLQHPALRVLQHDV
                     RTQGFPEETFDLIVARSVLCHLPEREAVLARMVSWLRPGGRLHVEDPSFFPAASSADPV
                     VRRLGGAVIATLAGTLGSDVDGWARSFPAPLLGLGLAEVGMRVHCPTLTSKNAAGTAWR
                     LSVAELLPVMDRLGVLPEADTVEALAHLEHPEFADVAHAMIGMWGVRPAGRPGERRHGV
                     DQTG"
     gene            3606..4991
                     /locus_tag="SSCG_02152"
     CDS             3606..4991
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 57.1; E-value: 2.9e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SSCG_02152"
                     /product="hypothetical protein"
                     /protein_id="EDY49124.1"
                     /transl_table=11
                     /translation="MTASAQTRKAVVVGSGIAGTAAAYRLRQAGYDILLLEQENHLGGR
                     MSSYTKDGDGAQYRIDRGASWLSHNYRPMIELLEETGLASRMLPCSNELGVLRDGRVHR
                     LSFVRPSDLLRTRLFGWRSKLKAVNLLRDLGTARRVLRWHDMSKAAGIDTENARDYALR
                     RLDRPLLDYLVEPLCSTQFLVPAEEVAAVGTFCIMWGTFGAASFTFDGGIGQLPTLLLD
                     LPLMRTERTRVETNAQVTDVRPDGDGVRVTWESGGTRHTENTDACVVAVPGPAAAGIVA
                     SLTDDQRSYLDGLRYTSDVHVTFGLREAPRETALGISVPRVEHPDLCVVLFEHNLGPGR
                     APAGRGLVTLLFRHHWSAERLALDDTRIVDDSLTALRETLPGLAAHIVGHRDMTTVQRW
                     DRAVLARPAGGYRDLARFTGSLDPRSPIQLAGDHFSYSTTNASMTTGEQAARRIISAAG
                     PTT"
ORIGIN
        1 tcaggaaccg tcgccggagt ccgccgggcg ggagcggcgg ctgacggtca tggtgacggg
       61 ctcggggccg agtgtggcgg ctgccacggg gcgggggcgg ctgcccggtg ccaggtccag
      121 gttccacttg gctgtgaggg tggcggcgag cagggtgagt tccgcgaggg cgaagtcgcc
      181 cccggggcag ccgtggacac cggcggcgaa ggggatgtag gcgccgcgcg ggggctgttc
      241 atggcggtcc gggtcccatc ggtcgggttc gaaggtgtcg ggccggaagt accagcgggg
      301 gtcgcggtgc agggcgtagg ggctgtagaa gagctgggta ccgcgcatga tcgggtaccc
      361 gtccagccgg agatcgtcgg cggcgcgccg ggggaacagc cagacgggcg ggtagagccg
      421 cagggtctcc tgcaccacgc ggcgggtgtg gaccagcgcg ggaaggtccg ccggggtggc
      481 ggagcgtccg ccgagaacgc ggtcgacctc ctggtggagg cgtcggcggg cctccgggtg
      541 ccggctgagg aggatgaaca gccaggaggc cgccgctccg ctggtgtggg aaccgccgat
      601 gaggagggag gtcacatcgt cgtggagctg gcgctcgtcg attccctcgg acagtgcggt
      661 catggtgggg gtgtcccggt tggcggcgat gagggtgtcc accacgtcgt gaatgcgggt
      721 gagggcactt cggtacttcg tgcgttcggg gttggggacc cggtcgagga ggaccgccgc
      781 cggtccgtag gcccggcgtg ccagcccggc gacgacgagg gggagctggt ggtggatgac
      841 ggagccgaac ccggccggga ggctctgtcc gaagacggtg gcggcgacga cgttcatggt
      901 gacatcggcc atctcggcgt tgaggtcgat ccgccggccg tcgctccagc cgtccgcccg
      961 ggcggcggcc agctccgcca tgctctccag ataggtttcc aggcggctgt ggctcagcag
     1021 cggctggacc gcgcgtcggc ggtcgcggtg gtgatcgccg ttggccacgg cgacgccgtt
     1081 cccgaacaag ggggaggcga tggcgaagat ctcgccgcgg tcgaagcgcc ggcgggaccc
     1141 ggtcagcagg gactggacga gatcgggatg gttgaggatg taggcaggct ggcgtcctat
     1201 gcggaactcc acgacgtccc cgcggccgcg ctgctcgtcg aggaaggcca gcggctttcc
     1261 gatcaggcgc accgcgtggc ccaggaaggg aagacagccg ggggcgaggg ggatggggcg
     1321 ggccgtgtgt ccggggggtg ccgtcatgtc agtccgttcc cgtcccggtg gttccgggtc
     1381 gatagcgcgg tgtctccagg ccccattcca gatggccgcg gacccagacg aggagggagg
     1441 ccgcacagtc gtcggcatgc gtccgtacgg tgtcgggcag gccgagtgcg gcggtgaggc
     1501 cggtgagatc ccggcgggcg gaggtatggg cgcgcatccg ctgttcgcag gcggccgaca
     1561 ccgcggcgct cgcggtccgc cggtcctggt gccggtcgtg ttcggtgacg agcacgaggt
     1621 tgtggaggtc tccgtgcgcg gcctccttgt ccaccgtcat caggtcgttg gtccagcaca
     1681 ccaggtccgc cgcggcggtc aggaggctct ggtaggggcg ggagtagtag acgcacgacg
     1741 gcagtgcgcc gccgtccgtt ctctcgatca ggtcgaacga cggcatgatc gcgccgaacg
     1801 cgcggcgcca gtgggggaac acctcggggt cggggaactc tccggcctgt cggtgggctg
     1861 cctgccagac acaggcgagg aggtagtcgc tgatgttgcg gcggaatctg agctgccagg
     1921 cgtctcccat cccggccgac gcctgcgtga tgatctcttc cagtgcccgg ctcatcgggc
     1981 cggaggcggt gcggatgccc agggccaccc cctggaggtc ttgaaggtgt ccgtcgagga
     2041 ggtcggcgtc ccggcccagg tcgctctcgt cgatccggtc gtcgaggagg aagagccagg
     2101 ccatccactt cgttatcagg gtgaggtcgt cctcggtggc cttcggatgg cagaaggcgg
     2161 ccagcaggcc gggccggatg cgggccaggt tcgccgactc cgccgtgtcg tgcccgcaga
     2221 gttcacccgc ctccacccag acgagcgtct tgccgtcggc cgcggcggcg tgggggctgt
     2281 gcggggagag gacgtcccag atcgccgatc cctcaaccgg tctggtcgac accgtgcctc
     2341 cgttccccgg gtcggcccgc cgggcggaca ccccacatgc cgatcatcgc gtgggccaca
     2401 tcggcgaact ccggatgctc caggtgcgcg agggcttcaa cggtgtccgc ctccggcagg
     2461 acgcccagcc ggtccatgac cggcagcagc tcggccaccg agagccgcca agcggttccc
     2521 gccgcgttct tcgaggtcag tgtggggcag tggacacgca ttcccacctc ggcgagtccc
     2581 aggccgagga gcggtgcggg aaaggaccgc gcccatccgt ccacatcgct cccgagcgtc
     2641 ccggccaggg tcgcgatgac cgcgcccccc aggcgccgta ccaccggatc ggccgaggac
     2701 gcggcgggga agaaggaagg atcttcgaca tggaggcgtc cccccggtct cagccaggac
     2761 accatcctgg ccagtaccgc ctcccgctcg ggcagatggc acagaacgct gcgggccacg
     2821 atcagatcaa acgtttcttc agggaatccc tgggttcgca catcatgctg aagaacccgc
     2881 agggcggggt gctgaagccc ggccatgaac cggatatcgg tatcggtggc cgtgacctcg
     2941 ccgcccgtgc accgcccggc gagccacagg gccacggtcc cggcacccgc gccgatctcc
     3001 agacaccgcg ctcccggcgg taaggcccat tccgacagac tggctttcgt cacagggtcg
     3061 cacacggcgg ccagggctct gaggcgatcc atctgtgcgg ggtggccgga ggcgaatatc
     3121 tcatcaccgt aatccggagg atcgctgtcg gccgagcatc tcctgcgcat ccgacacttc
     3181 cttctcgata aaaggaacat atgcctggtg ctctgaatcc ctggcgcgta tgccgggggt
     3241 accgacggcg cgccgcgctg gtcttcgtgg tgcggtgcgc tggtcttcgt ggtgcggtgc
     3301 ggtaacgccc gggcgccgcc atgttcccgg gtgtgccgca tcgccaaggg gtgagtccct
     3361 gtcgatcaga ccagggcagt cgatccgtgt caatggcatc tatcttgttc ccgcccgcgg
     3421 gcagccgggg tgatgttcgg tcattccgga cattgctcgg tgagtggcgg gtatcgcagc
     3481 cgtgctccgc gcgacagggg cgtcattgac agggaacctg cgcaggtgca tggtcatgct
     3541 gctgccggac tccatggcct ttgcgcaagc acccaagaca tcagggacgc ccgaggaggc
     3601 gctgaatgac agcgagcgca cagacgagga aagcggtcgt cgtcggctcc ggaatagcgg
     3661 gaacagccgc cgcataccgg ctccggcaag caggctacga cattctgctg ctggaacagg
     3721 agaatcacct cggtggccgc atgtcctcgt acaccaagga cggcgacggc gcccaatacc
     3781 gtatcgaccg gggcgcgagc tggctttccc acaattaccg gcccatgatc gaactgctgg
     3841 aggagacggg actcgcctcc cgcatgctgc cctgctccaa tgaactgggc gtactccgtg
     3901 acggaagagt ccaccgcctg tccttcgtcc ggccatccga tctgctccgg acccggctgt
     3961 tcggatggcg gtccaaactg aaggccgtga acctcctgcg tgacctcggg acggcacgcc
     4021 gcgtgctgcg ctggcacgac atgtcgaagg ccgccggaat cgacaccgaa aacgcccggg
     4081 actacgccct gcgccgactc gaccggcccc tgctcgacta tctggtggaa cccctgtgca
     4141 gcacccagtt cctcgtcccg gccgaggagg tcgcggccgt cgggaccttc tgcatcatgt
     4201 ggggcacctt cggcgcggcg agcttcacct tcgacggcgg catcggccaa ctgcccaccc
     4261 tcctgctcga cctgcccctc atgcgcacag agcggacccg tgtcgagacg aacgcacagg
     4321 tgaccgacgt caggcccgac ggggacggcg ttcgcgtcac ctgggagagc ggcggaaccc
     4381 gccataccga gaacactgac gcctgtgtcg tggccgtccc cggaccggcc gcggccggga
     4441 tcgtcgcctc cctcaccgac gaccagcgct cctacctcga cggactccgc tacaccagcg
     4501 acgtccacgt caccttcgga cttcgcgagg caccccggga aaccgccctg ggcatctccg
     4561 ttccccgggt ggaacatccc gacctctgcg tcgtgctgtt cgaacacaac ctcggccccg
     4621 gccgggcccc tgcgggccgg ggcctggtca ccctcctctt ccgccaccac tggagcgccg
     4681 aacgtctcgc cctcgacgac acccggatcg tcgacgactc cctcaccgct ctccgggaga
     4741 cgctccccgg cctcgccgcc catatcgtcg ggcaccgcga catgaccact gtccagcggt
     4801 gggacagagc cgtcctcgcc cgccccgcag gcggctaccg cgacctcgcc cgtttcaccg
     4861 gcagcctgga cccccggtcg ccgatccagc tcgcggggga ccacttctcg tacagcacca
     4921 ccaacgcgtc gatgaccaca ggggaacagg ccgcccggcg tatcatctcc gccgccggtc
     4981 cgacgacatg a
//
