BGC0000679: diazepinomicin biosynthetic gene cluster from Micromonospora sp. M42
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Location: 255,998 - 303,913 nt. (total: 47,916 nt).
This entry is originally from NCBI GenBank KK037233.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000679
Short description diazepinomicin biosynthetic gene cluster from Micromonospora sp. M42
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene
Loci NCBI GenBank: KK037233.1
Compounds
  • diazepinomicin
Species Micromonospora sp. M42 [taxonomy]
References
Chemical products information
diazepinomicin
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C28H34N2O4
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • MCBG_00164
  • EWM63031.1
 255998 - 258175 (-) membrane protein
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  • MCBG_00165
  • EWM63032.1
 258777 - 260792 (+) LigA protein
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  • MCBG_00166
  • EWM63033.1
 260847 - 263534 (-) LigA protein
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  • MCBG_00167
  • EWM63034.1
 263936 - 265024 (+) polyprenyl synthetase
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  • MCBG_00168
  • EWM63035.1
 265039 - 266079 (+) mevalonate kinase
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  • MCBG_00169
  • EWM63036.1
 266069 - 267109 (+) diphosphomevalonate decarboxylase
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  • MCBG_00170
  • EWM63037.1
 267106 - 268215 (+) phosphomevalonate kinase
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  • MCBG_00171
  • EWM63038.1
 268212 - 269294 (+) isopentenyl-diphosphate delta-isomerase, type 2
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  • MCBG_00172
  • EWM63039.1
 269291 - 270346 (+) hydroxymethylglutaryl-coenzyme A reductase
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  • MCBG_00173
  • EWM63040.1
 270349 - 271524 (+) hydroxymethylglutaryl-CoA synthase
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  • MCBG_00174
  • EWM63041.1
 271561 - 272466 (+) hypothetical protein
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  • MCBG_00175
  • EWM63042.1
 272590 - 273690 (+) two-component system sensor kinase
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  • MCBG_00176
  • EWM63043.1
 273687 - 274349 (+) two-component system response regulator
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  • MCBG_00177
  • EWM63044.1
 274541 - 274936 (+) hypothetical protein
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  • MCBG_00178
  • EWM63045.1
 275000 - 275455 (+) hypothetical protein
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  • MCBG_00179
  • EWM63046.1
 275452 - 277470 (+) multicopper oxidase
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  • MCBG_00180
  • EWM63047.1
 277467 - 277871 (+) glyoxalase
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  • MCBG_00181
  • EWM63048.1
 278013 - 278480 (-) hypothetical protein
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  • MCBG_00182
  • EWM63049.1
 278575 - 280539 (-) anthranilate synthase, phenazine specific
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  • MCBG_00183
  • EWM63050.1
 280793 - 282058 (+) aspartate kinase 2
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  • MCBG_00184
  • EWM63051.1
 282074 - 282895 (+) fructose-bisphosphate aldolase
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  • MCBG_00185
  • EWM63052.1
 282927 - 284030 (+) 3-dehydroquinate synthase
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  • MCBG_00186
  • EWM63053.1
 284056 - 284817 (+) metal-dependent hydrolase
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  • MCBG_00187
  • EWM63054.1
 284871 - 286130 (+) hypothetical protein
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  • MCBG_00188
  • EWM63055.1
 286141 - 287331 (+) monooxygenase
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  • MCBG_00189
  • EWM63056.1
 287331 - 288116 (+) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
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  • MCBG_00190
  • EWM63057.1
 288155 - 288829 (+) isochorismatase
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  • MCBG_00191
  • EWM63058.1
 288841 - 289542 (+) oxidoreductase, short chain dehydrogenase/reductase family
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  • MCBG_00192
  • EWM63059.1
 289535 - 290275 (-) LigA protein
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  • MCBG_00193
  • EWM63060.1
 290471 - 290806 (+) integral membrane protein
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  • MCBG_00194
  • EWM63061.1
 290803 - 292482 (+) sodium:solute symporter
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  • MCBG_00195
  • EWM63062.1
 292495 - 294141 (+) FAD-binding monooxygenase
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  • MCBG_00196
  • EWM63063.1
 294220 - 295461 (+) phospho-2-dehydro-3-deoxyheptonate aldolase
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  • MCBG_00197
  • EWM63064.1
 295636 - 296745 (+) hypothetical protein
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  • MCBG_00198
  • EWM63065.1
 296926 - 298407 (+) hypothetical protein
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  • MCBG_00199
  • EWM63066.1
 298507 - 298854 (+) transcriptional regulator, PadR family
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  • MCBG_00200
  • EWM63067.1
 298851 - 299882 (+) hypothetical protein
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  • MCBG_00201
  • EWM63068.1
 299879 - 300160 (-) acyl-CoA oxidase
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  • MCBG_00202
  • EWM63069.1
 300336 - 302015 (-) acyl-CoA oxidase
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  • MCBG_00203
  • EWM63070.1
 302192 - 303913 (+) ABC transporter ATP-binding protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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