BGC0000692: apramycin biosynthetic gene cluster from Streptoalloteichus hindustanus
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Location: 1 - 39,979 nt. (total: 39,979 nt).
This entry is originally from NCBI GenBank AJ875019.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000692
Short description apramycin biosynthetic gene cluster from Streptoalloteichus hindustanus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: AJ875019.1
Compounds
  • apramycin
Species Streptoalloteichus hindustanus [taxonomy]
References
Chemical products information
apramycin
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C21H41N5O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ShinN01.1c
  • CAI47636.1
  • aprN
 1 - 516 (-) putative aminoglycoside N-acetylhexosaminyl deacetylase
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  • ShinN01.2c
  • CAI47637.1
  • aprW
 632 - 2512 (-) putative ABC-type aminoglycoside exporter
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  • ShinN01.3c
  • CAI47638.1
  • aprV
 2509 - 4311 (-) putative ABC-type aminoglycoside exporter
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  • ShinN01.4
  • CAI47639.1
  • aprU
 4608 - 5618 (+) putative apramycin kinase
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  • ShinN01.5
  • CAI47640.1
  • aprA
 7080 - 8207 (+)
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  • ShinN01.6
  • CAI47641.1
  • kamB
 8483 - 8950 (+) 16S rRNA methyltransferase
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  • ShinN01.7c
  • CAI47642.1
  • aprO
 8940 - 11282 (-) putative phosphorylase or hydrolase
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  • ShinN01.8c
  • CAI47643.1
  • aprD1
 11279 - 12217 (-) putative tobramycin/apramycin biosynthetic oxidoreductase
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  • ShinN01.9c
  • CAI47644.1
  • aprF
 12233 - 13510 (-) putative apramycin biosynthesis protein
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  • ShinN01.10c
  • CAI47645.1
  • aprG
 13507 - 14403 (-) putative apramycin biosynthesis protein
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  • ShinN01.11
  • CAI47646.1
  • aprH
 15344 - 16420 (+) putative glycosyltransferase
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  • ShinN01.12
  • CAI47647.1
  • aprI
 16508 - 17296 (+) putative N-methyltransferase
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  • ShinN01.13c
  • CAI47648.1
  • aprJ
 17405 - 18118 (-) putative phosphosugar mutase
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  • ShinN01.14c
  • CAI47649.1
  • aprK
 18122 - 18613 (-) putative NDP-octose synthase
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  • ShinN01.15c
  • CAI47650.1
  • aprM
 18671 - 20080 (-) putative glycosyltransferase
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  • ShinN01.16c
  • CAI47651.1
  • aprC
 20084 - 21244 (-) putative 2-deoxy-scyllo-inosose synthase
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  • ShinN01.17c
  • CAI47652.1
  • aprS
 21278 - 22552 (-) putative ketocyclitol aminotransferase
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  • ShinN01.18c
  • CAI47653.1
  • aprE
 22658 - 23674 (-) putative 3-amino-2,3-dideoxy-scyllo-inositol 1 dehydrogenase
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  • ShinN01.19c
  • CAI47654.1
  • aprP
 23779 - 24597 (-) putative amidohydrolase
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  • ShinN01.20c
  • CAI47655.1
  • aprD2
 24594 - 25556 (-) putative tobramycin/apramycin oxidoreductase
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  • ShinN01.21c
  • CAI47656.1
  • aprD3
 25814 - 26560 (-) putative tobramycin/apramycin oxidoreductase 3
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  • ShinN01.22
  • CAI47657.1
  • aprQ
 27767 - 29278 (+) putative hexosamine-6-dehydrogenase
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  • ShinN01.23
  • CAI47658.1
  • aprD4
 29339 - 30709 (+) putative Fe-S oxidoreductase 4
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  • ShinN01.24
  • CAI47659.1
  • aprZ
 30734 - 32134 (+) putative 6-phosphate phosphatase
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  • ShinN01.25
  • CAI47660.1
  • aprL
 32251 - 33372 (+) putative aminotransferase
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  • ShinN01.26
  • CAI47661.1
  • aprD5
 33425 - 34462 (+) putative epimerase/dehydratase
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  • ShinN01.27
  • CAI47662.1
  • N01.27
 35325 - 36674 (+) putative phenylacetyl-CoA ligase
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  • ShinN01.28c
  • CAI47663.1
  • N01.28c
 36760 - 37563 (-) putative membrane protein
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  • ShinN01.29c
  • CAI47664.1
  • N01.29c
 37578 - 38120 (-) putative membrane protein
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  • ShinN01.30
  • CAI47665.1
  • N01.30
 38333 - 39052 (+) putative membrane protein
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  • ShinN01.31
  • CAI47666.1
  • N01.31
 39281 - >39979 (+) putative glutamyl endopeptidase precursor
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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