BGC0000698: hygromycin A biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 39,151 nt. (total: 39,151 nt).
This entry is originally from NCBI GenBank DQ314862.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000698
Short description hygromycin A biosynthetic gene cluster from Streptomyces hygroscopicus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
DQ314862.1
via
Compounds
  • hygromycin A
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
hygromycin A Evidence:
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C23H29N1O12
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC42538.1
 2270 - 3397 (-) putative AfsR regulatory protein
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    • ABC42539.1
    		 3717 - 4916 (-) putative p-hydroxybenzoate hydroxylase
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      • ABC42540.1
      		 5308 - 6279 (+) putative regulatory protein
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        • ABC42541.1
        		 6452 - 6973 (+) putative chorismate lyase
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          • ABC42542.1
          		 7011 - 8069 (+) putative mannose dehydratase
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            • ABC42543.1
            		 8342 - 9091 (+) putative methyltransferase
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              • ABC42544.1
              		 9084 - 10823 (+) unknown
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                • ABC42545.1
                		 10911 - 12146 (+) putative aminotransferase
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                  • ABC42546.1
                  		 12149 - 12400 (+) putative acyl carrier protein
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                    • ABC42547.1
                    		 12397 - 13533 (+) putative beta-ketoacyl synthase 1
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                      • ABC42548.1
                      		 13533 - 14291 (+) unknown
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                        • ABC42549.1
                        		 14294 - 15649 (+) putative Co-A ligase
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                          • ABC42550.1
                          		 15715 - 16005 (+) putative acyl carrier protein
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                            • ABC42551.1
                            		 16002 - 17045 (+) putative 3-hydroyacyl ACP dehydratase
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                              • ABC42552.1
                              		 17012 - 17782 (+) putative 3-ketoacyl ACP reductase
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                                • ABC42553.1
                                		 17817 - 19112 (+) putative glycosyltransferase
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                                  • ABC42554.1
                                  		 19109 - 20101 (+) putative myo-inositol dehydrogenase
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                                    • ABC42555.1
                                    		 20193 - 21284 (+) putative myo-inositol-1-phosphate synthase
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                                      • ABC42556.1
                                      		 21344 - 22594 (+) putative transmembrane protein
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                                        • ABC42557.1
                                        		 22599 - 23714 (+) putative transglucosylase
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                                          • ABC42558.1
                                          		 23787 - 24338 (-) putative phosphotransferase
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                                            • ABC42559.1
                                            		 24603 - 25778 (+) putative acyltransferase
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                                              • ABC42560.1
                                              		 25788 - 26765 (+) putative fucose synthase
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                                                • ABC42561.1
                                                		 26786 - 27649 (-) unknown
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                                                  • ABC42562.1
                                                  		 27762 - 28403 (+) putative myo-inositol-1-phosphatase
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                                                    • ABC42563.1
                                                    		 28423 - 29238 (-) putative short chain dehydrogenase
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                                                      • ABC42564.1
                                                      		 29701 - 30906 (+) putative DAHP synthase
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                                                        • ABC42565.1
                                                        		 30998 - 32710 (+) putative ABC transporter
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                                                          • ABC42566.1
                                                          		 32643 - 33779 (-) putative methyltransferase
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                                                            Biosynthesis information
                                                            Annotation changelog

                                                            Entry version: 4

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-10-07
                                                            Update chemical activity to schema version 2.11
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 3

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2022-09-15
                                                            Updated bioactivity data
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 2

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2019-10-16
                                                            Migrated from v1.4
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            2019-10-16
                                                            Updated compound(s) information (NPAtlas curation)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            2015-06-12
                                                            Submitted
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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