BGC0000703: kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1,695,607 - 1,729,284 nt. (total: 33,678 nt).
This entry is originally from NCBI GenBank CP023699.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000703
Short description kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: CP023699.1
Compounds
  • kanamycin
Species Streptomyces kanamyceticus [taxonomy]
References
Chemical products information
kanamycin
Copy SMILES
C18H36N4O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CP970_06595
  • QEU90618.1
1695608 - 1698106 (-) PAS domain-containing protein
copy AA seq
copy Nt seq
  • CP970_06600
  • QEU90619.1
1698248 - 1700683 (-) MFS transporter
copy AA seq
copy Nt seq
  • CP970_06605
  • QEU90620.1
1700887 - 1701330 (-) SRPBCC family protein
copy AA seq
copy Nt seq
  • CP970_06610
  • QEU90621.1
1701452 - 1702699 (-) arsenic transporter
copy AA seq
copy Nt seq
  • CP970_06615
  • QEU90622.1
1702765 - 1702959 (-) antitoxin
copy AA seq
copy Nt seq
  • CP970_06620
  • QEU90623.1
  • aac_6__
1703052 - 1703525 (+) aminoglycoside 6'-N-acetyltransferase
copy AA seq
copy Nt seq
  • CP970_06625
  • QEU90624.1
1703591 - 1704757 (-) hypothetical protein
copy AA seq
copy Nt seq
  • CP970_06630
  • QEU90625.1
1704759 - 1705286 (-) hypothetical protein
copy AA seq
copy Nt seq
  • CP970_06635
  • QEU97141.1
1705404 - 1705847 (-) hypothetical protein
copy AA seq
copy Nt seq
  • CP970_06640
  • QEU90626.1
1706314 - 1707423 (+) streptomycin biosynthesis protein
copy AA seq
copy Nt seq
  • CP970_06645
  • QEU90627.1
1707362 - 1708549 (+) hypothetical protein
copy AA seq
copy Nt seq
  • CP970_06650
  • QEU90628.1
1708648 - 1709889 (+) MFS transporter
copy AA seq
copy Nt seq
  • CP970_06655
  • QEU90629.1
1709442 - 1711073 (+) aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
copy AA seq
copy Nt seq
  • CP970_06660
  • QEU90630.1
1711081 - 1712607 (+) GMC family oxidoreductase
copy AA seq
copy Nt seq
  • CP970_06665
  • QEU90631.1
1712726 - 1714009 (+) DegT/DnrJ/EryC1/StrS family aminotransferase
copy AA seq
copy Nt seq
  • CP970_06670
  • QEU90632.1
1714051 - 1715223 (+) iron-containing alcohol dehydrogenase
copy AA seq
copy Nt seq
  • CP970_06675
  • QEU90633.1
1715220 - 1716341 (+) gfo/Idh/MocA family oxidoreductase
copy AA seq
copy Nt seq
  • CP970_06680
  • QEU90634.1
1716490 - 1717746 (+) glycosyltransferase family 1 protein
copy AA seq
copy Nt seq
  • CP970_06685
  • QEU90635.1
1717743 - 1718492 (+) PIG-L family deacetylase
copy AA seq
copy Nt seq
  • CP970_06690
  • QEU90636.1
1718489 - 1719748 (+) DegT/DnrJ/EryC1/StrS family aminotransferase
copy AA seq
copy Nt seq
  • CP970_06695
  • QEU90637.1
1719907 - 1720764 (+) hypothetical protein
copy AA seq
copy Nt seq
  • CP970_06700
  • QEU90638.1
1720739 - 1721848 (+) NAD-dependent epimerase/dehydratase family protein
copy AA seq
copy Nt seq
  • CP970_06705
  • QEU90639.1
1721974 - 1722807 (+) 16S rRNA methyltransferase
copy AA seq
copy Nt seq
  • CP970_06710
  • QEU90640.1
1722890 - 1724134 (+) glycosyltransferase family 1 protein
copy AA seq
copy Nt seq
  • CP970_06715
  • QEU90641.1
  • rsgA
1724193 - 1725200 (+) ribosome small subunit-dependent GTPase A
copy AA seq
copy Nt seq
  • CP970_06720
  • QEU97142.1
1725235 - 1725633 (+) RidA family protein
copy AA seq
copy Nt seq
  • CP970_06725
  • QEU90642.1
1725657 - 1726226 (-) adenylosuccinate lyase
copy AA seq
copy Nt seq
  • CP970_06730
  • QEU90643.1
1726581 - 1728362 (+) 3-hydroxyacyl-CoA dehydrogenase
copy AA seq
copy Nt seq
  • CP970_06735
  • QEU90644.1
1728349 - 1729284 (+) TetR family transcriptional regulator
copy AA seq
copy Nt seq
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added new publication with improved reference coordinates
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.