LOCUS       BGC0000817              6814 bp    DNA     linear   ENV 23-JAN-2014
DEFINITION  Uncultured bacterium clone NM343 methylarcyriarubin tryptophan dimer
            gene cluster, partial sequence.
ACCESSION   BGC0000817
VERSION     BGC0000817
KEYWORDS    .
SOURCE      uncultured bacterium
  ORGANISM  uncultured bacterium
            Bacteria; environmental samples.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:42:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5677
            Orig. end    :: 12491
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1056)
                     /codon_start=1
                     /gene="marM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 341.1; E-value:
                     1.1e-103)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="asmbl_6"
                     /product="N-methyltransferase MarM"
                     /protein_id="AHE14572.1"
                     /transl_table=11
                     /translation="MTTQGTPALPPSVALMQMITGSLVGQAIHVAAKLGVADALKDGPK
                     GREALAKDVGADPEALYRVLRALASFGIFAEDGEGRFALTPLAECLRSDVPGSMRAFAT
                     VFGEPWRWRTLGEIVHSVRTGQPAFDKLHGMNLFEYLTRNPEDARLFGEAMTSFSRREF
                     TGASIGEIDAVLQAYDFSAFRRVVDVAGGHGSFIAAALKANPGLGGVLFDVPPVIEDAR
                     KYLVAEGLVERCEAVGGSFFDGVPAGGDVYVMKRVIHDWDDARAAAILTQCRRAMAPGG
                     RVALVEMVIPAGNTPFFGKIVDLEMLLIGGRERTASEYRALLASAGFELTRIVPTQSPL
                     SIVEGVPVQGA"
     subregion       1..6814
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Alkaloid"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6814
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1056)
                     /gene="marM"
                     /locus_tag="asmbl_6"
     gene            1410..4838
                     /gene="marB"
                     /locus_tag="asmbl_7"
     CDS             1410..4838
                     /codon_start=1
                     /gene="marB"
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /locus_tag="asmbl_7"
                     /product="chromopyrrolic acid synthase MarB"
                     /protein_id="AHE14562.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1332.3,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILEFPRIHFRGTARIHVPTGNNNNIGAIDVGTNTVYRDGEKVD
                     LSQPPTEFHKYMREAAPRYNAAGEWDERGEFSKAAGWDFEGNSHFSWDARIVGTQVGPE
                     EAPSSAADPLVGRIIELWGHYNEYLGTTFNRARMVDCDPASNWATQVYAGQLTFGRKGP
                     SLETPNIFSADIQCVQHSRFLHFDHIRELVPHCNNPEFSGAALFQFTVSKTDDAFNWGE
                     EAEASPVLRALRKALERPGVRGLVVQYALSNMATTTKPDSPAFTDLVGSIGLWRQEELR
                     TYPAGRLLAPKVSLFKPKPGRPEAPKLGAALVQVSGSRVSFNMPITIPAVGRKPRLEAS
                     DGPTHPLGPPLALGTLELRVAGTDRLVARLPPEAYGWDAHQRTSGIIDVPLEPGDGAVR
                     DELERHGLYLTAETPDGGRVVVLEEEELNIQTDSGNLYVEFPNARKNALHAQCVEVRTF
                     LRGRPAAVRGLHLHQFYNPRAVPHLRYEFEKDPRNAGRTFDFPRSEDFPIAYFKPGRPE
                     DGGTYAPGCAFDTNEEGRGYVSVIGHRGGTARVLLSPHAERHVFPLQGDLRNEAEYNYD
                     NYDRIRCWGYLPGFHVRVLPDDWALEEVPDRDVDFTFLYQHVLGYYELIYPFMRSLVFS
                     LADRCKCETYARLMWQMCDPKNKDKTYYMPPTRELSHPKAMLFLKYLRNVERIGYVPPP
                     KAKQKTPHRKLESREHLVRALRDAVELELSLMLQYTYAAWSLPNYVTGCEYVERGLWTP
                     EQLKLVCGDGAEALDQGWRGTILEVAHEEMAHFLVANNLLMALGEPFYVPTVDLSGANR
                     FFPIDTEFALQPFSLGTLERFIEFEYPDYFEKEVETPPELAAVPEVAGLPVLATIPDLG
                     LDNGPGYSSVSELYQQIREAFETLPDLILVERGKQGGEHHLFLHEAINRKHPDYQLQVD
                     DVPSALFGVDFITQQGEGSSPDSPLYERSHFHRFRTIAQQLADQQTKHFQARRAPWNPA
                     YPALRNPTLRGREGAGNRVTVAETRQVMQITEGCYELMLQLMVQHFGLMPRASLRRSDL
                     MNASIDVMTGLLRPLGILLMTLPSGKKGRTAGPSFELDQAPAYISVPQVAYRVISTKFK
                     RLHELALPLPSVSDAVKELLLFYSDYFARWAAKAA"
     gene            4884..6221
                     /gene="marC"
                     /locus_tag="asmbl_8"
     CDS             4884..6221
                     /codon_start=1
                     /gene="marC"
                     /locus_tag="asmbl_8"
                     /note="[PR] COG4638 phenylpropionate dioxygenase and
                     related ring-hydroxylating dioxygenases large terminal
                     subunit"
                     /product="Rieske [2Fe-2S] domain dioxygenase MarC"
                     /protein_id="AHE14552.1"
                     /transl_table=11
                     /translation="MLSAEDNKLLTEVAADTRMGQLLRRYWHPIAASSQLDDKHPTRLV
                     HLLGEKLVLYKDKQGRLGLIDERCPHRRASMLYGIPEQEGLRCSYHGWLFNNAGRCLAQ
                     PYEQMEDPCSNFKDHVRIKSYPVRELGGLVFAYLGPAPAPELPAWDLLVTENLHRDIGF
                     AVVPCNWLQIMENAADPVHAEWLHGHFANYVWERLGKPERIKPFPTHKKIGFDLSEYGI
                     IKRRVLEGETEEHENWKFGHSLVFPNLQKGGGLQWRVPMDETRTLHVWYYTYTPAEGTV
                     VPKDAPIPVFDVPVPALDEHGHPRWDVLDFTAGQDMVMWYTQGAVAERWKETLGRSDRG
                     VIMYRNLLKANLEKLARGEEPMNVFRDPAKAAFIQLDTEESSGRRLYSDRARQYGPSSS
                     NGPGGGATKYSPVLNLHKGAETVSAKEVMPETALPAAPPAARKETA"
     gene            6218..6814
                     /gene="marE"
                     /locus_tag="asmbl_9"
     CDS             6218..6814
                     /codon_start=1
                     /gene="marE"
                     /locus_tag="asmbl_9"
                     /product="putative VioE-like protein MarE"
                     /protein_id="AHE14571.1"
                     /transl_table=11
                     /translation="MSAARQRPPLLPERQWSSSYVSYWSPMQGGDRMTSGHVWYDYGRG
                     VYRIDGVLNPWDEQAHGHLLWKSEINQFGAGECHTWAVAYDVPGEAAPTYRARPLAYER
                     TKSPGSLVPCDVLVRHEAVFVGTEQVLGFEAEGWRYERPEGRGPVTYYFRAGTRHLLRM
                     VNGDPRLHAAIRDFPTFSEQPIPDTVFQPHPWAAR"
ORIGIN
        1 tcaggcgccc tggacgggca cgccctcgac gatgctcagc ggcgactgcg tggggacgat
       61 gcgcgtcagc tcgaagcccg ccgaggccag cagcgcgcgg tactcgctcg cggtgcgctc
      121 acgcccgccg atgagcagca tctccaggtc cacaatcttg ccgaagaacg gcgtgttgcc
      181 cgcgggaatc accatctcca ccagggccac gcggccaccg ggcgccatgg cgcggcggca
      241 ctgggtgagg atggcggcgg cgcgcgcgtc gtcccagtcg tggatgacgc gcttcatcac
      301 atagacgtcg cccccggccg gcacgccgtc gaagaagctg ccgcccaccg cctcgcagcg
      361 ctccaccagc ccctcggcca cgaggtactt gcgcgcgtcc tcgatgacgg ggggcacgtc
      421 gaagagcacg ccccccagcc ccgggttggc cttgagcgcg gcggcgatga agctgccgtg
      481 cccgccggcc acgtccacca cccggcggaa ggccgagaag tcataggcct gcagcacggc
      541 gtcgatttcg ccaatggagg ccccggtgaa ctcgcgccgg gagaagctcg tcatcgcctc
      601 gccgaagagc cgggcgtcct ccgggttgcg ggtgaggtac tcgaacaggt tcatcccgtg
      661 cagcttgtcg aaggccggct gccccgtcct gacgctgtgg acgatttccc ccagcgtccg
      721 ccagcgccac ggctcgccga acaccgtcgc gaaggcccgc atggaccccg gcacgtcgct
      781 gcgcaggcac tcggccagcg gggtgagcgc gaagcggccc tcgccgtcct ccgcgaagat
      841 gccgaagctg gccagcgcgc gcagcacccg gtagagcgcc tccgggtccg cccccacgtc
      901 cttcgccagc gcctcgcgcc ccttggggcc gtccttcagc gcgtccgcca cgcccagctt
      961 cgccgccacg tggatggcct gccccaccag cgagccggta atcatctgca tcagcgccac
     1021 cgagggcgga agcgcgggcg ttccctgagt tgtcatttca agctcctcat gcccagacgt
     1081 ctggccatgt gcgggccggg ctgggggcct cttgctacat ccgggtccac aagaaaagtc
     1141 ggaaagacgt cagcgcgccg cgcccgaaac gtgttcagtg gtagacaaag cacccccctg
     1201 aactgatgaa tccctgactt gacactgttc gcggattact ctttaagatg agtaagtccg
     1261 gtggtgggtg gccaagcacc tgtccaggcc tccgggcggc ccgtgaaagc accgcgtcct
     1321 ccgtcctcat gaggggccgt gtctggcttt gccgtgttca agggggacac ggggccatca
     1381 attcccaagc tgttgcgaaa aagcccgcca tgagcatcct ggaatttccg cgcatccact
     1441 tccggggcac cgctcgcatc catgtgccga cgggaaacaa caacaacatc ggcgcgattg
     1501 atgtcgggac caacaccgtc taccgcgacg gtgagaaggt ggacctgagc cagcctccca
     1561 ccgagttcca caagtacatg cgggaggcgg cgccccggta caacgcggcc ggggagtggg
     1621 acgagcgcgg cgagttcagc aaggccgcgg gctgggactt cgagggcaac agccacttct
     1681 cctgggacgc gcgcatcgtc ggcacgcagg tggggccgga ggaggcgccc tcgtccgcgg
     1741 cggacccgct ggtgggacgc atcatcgagc tgtggggcca ctacaacgag tacctcggca
     1801 ccacgttcaa ccgggcccgc atggtggact gcgatccagc gtccaactgg gccacgcagg
     1861 tgtacgcggg gcagctcacc ttcggccgca aggggccgtc gctggagacg cccaacatct
     1921 tctcggcgga catccagtgc gtgcagcaca gccgcttctt gcacttcgac cacatccggg
     1981 agctggtgcc ccactgcaac aacccggagt tctccggggc cgccctcttc cagttcaccg
     2041 tctccaagac ggacgacgcc ttcaactggg gcgaggaggc cgaggcgtcc ccggtgctgc
     2101 gcgccctgcg caaggcgctg gagaggcccg gggtgagggg gctggtggtg cagtacgccc
     2161 tctccaacat ggccaccacc acgaagccgg actcgccggc cttcacggac ctggtgggga
     2221 gcatcggcct gtggcggcag gaggagctgc gcacctaccc cgccggccgg ctgctggccc
     2281 ccaaggtgtc gctgttcaag ccgaagccgg gccggcccga ggcgccgaag ctgggcgcgg
     2341 ccctggtgca ggtgtccggc agccgggtct ccttcaacat gcccatcacc attcccgcgg
     2401 tgggccgcaa gccgaggctg gaggccagtg atggccccac ccacccgctg ggcccgcccc
     2461 tggcgctggg cacgctggag ctgcgcgtgg cgggcaccga caggctggtg gcgcgcctgc
     2521 cccccgaggc ctacggctgg gacgcgcacc agcgcacctc gggcatcatc gacgtgccgc
     2581 tggagccagg cgacggcgcc gtgcgcgacg agctggagcg gcacggcctc tacctcaccg
     2641 ccgagacgcc ggacggcggg cgcgtggtgg tgctcgagga ggaggagctc aacatccaga
     2701 cggactcggg caacctctac gtcgagttcc ccaacgcccg gaagaacgcg ctgcacgccc
     2761 agtgcgtgga ggtgcgcacc ttcctgcgcg gccggcccgc ggcggtgcgg gggctgcacc
     2821 tgcaccagtt ctacaacccg cgcgccgtgc cccacctgcg ctacgagttc gagaaggacc
     2881 cgcgcaacgc cgggcgcacc ttcgacttcc cccggagcga ggacttcccc atcgcgtact
     2941 tcaagcccgg ccgtcccgag gacggcggca cgtacgcgcc tggctgcgcc ttcgacacca
     3001 acgaggaggg gcgcggctac gtcagcgtca tcggccaccg gggcggcacc gcgcgggtgc
     3061 tgctgtcccc ccacgccgag cgccacgtct tcccgctcca gggcgacctg cgcaacgagg
     3121 ccgagtacaa ctacgacaac tacgaccgca tccgctgctg gggctacctg cccggcttcc
     3181 acgtccgcgt cctgccggac gactgggcgc tggaggaggt gccggaccgg gacgtggact
     3241 tcacgttcct ctaccagcac gtgctcggct actacgagct catctacccc ttcatgcgct
     3301 cgctggtctt cagcctcgcg gaccgctgca agtgcgagac gtacgcgcgg ctgatgtggc
     3361 agatgtgcga cccgaagaac aaggacaaga cctactacat gccccccacg cgcgagctgt
     3421 cgcacccgaa ggcgatgctc ttcctgaagt acctgcgcaa cgtggagcgc atcggctacg
     3481 tgccgccgcc caaggcgaag cagaagacgc cgcaccgcaa gctggagtcg cgcgagcacc
     3541 tggtgcgcgc gctgcgggac gccgtcgagc tggagctgtc cttgatgctc cagtacacgt
     3601 acgcggcctg gtcgctgccc aactacgtga cggggtgcga gtatgtggag cgcgggctgt
     3661 ggacgcccga gcagctcaag ctggtgtgcg gcgacggcgc cgaggcgctg gaccagggct
     3721 ggcgcggcac catcctggag gtggcccacg aggagatggc ccacttcctg gtggccaaca
     3781 acctgctgat ggcgctgggc gagcccttct acgtccccac cgtggacctg tcgggcgcca
     3841 accgcttctt ccccatcgac accgagttcg cgctccagcc cttctcgctg ggcaccctgg
     3901 agcgcttcat cgagttcgag tacccggact acttcgagaa ggaggtggag acgcctccgg
     3961 agctggccgc cgtcccggag gtggccggcc tgccggtgct ggccaccatc ccggacctgg
     4021 gcctggacaa tggcccgggg tacagctcgg tgagcgagct gtaccagcag attcgcgagg
     4081 ccttcgagac gctgccggac ctcatcctgg tggagcgggg caagcagggc ggcgagcacc
     4141 acctgttcct gcacgaggcc atcaaccgca agcacccgga ctaccagctc caggtggatg
     4201 acgtgcccag cgcgctgttc ggcgtggact tcatcaccca gcagggcgag ggctcgtcgc
     4261 cggactcgcc gctgtacgag cgctcgcact tccaccgctt ccgcaccatt gcccagcagc
     4321 tcgcggacca gcagacgaag cacttccagg cccggcgcgc gccgtggaac ccggcctacc
     4381 ccgcgctgcg caaccccacc ctgcgcggcc gcgagggcgc cggcaaccgc gtcaccgtgg
     4441 ccgagacgcg ccaggtgatg cagataacgg agggctgcta cgagctgatg ctccagctca
     4501 tggtgcagca cttcgggctg atgccgcgcg ccagcctgcg gcgctcggac ctgatgaacg
     4561 cctccatcga cgtgatgacg gggctgctca ggccgctggg catcctgctg atgacgctgc
     4621 cctcggggaa gaaggggcgc accgccggcc cgtcgttcga gctggaccag gcccccgcgt
     4681 acatctccgt gccccaggtg gcctacaggg tcatctccac caagttcaag cgcctgcacg
     4741 agctcgccct gccgctgccg tcggtgagcg acgccgtgaa ggagctgctg ctcttctaca
     4801 gcgactactt cgccaggtgg gccgccaagg cggcctagtg gcgccccccc gccgttccac
     4861 tcttgtgagg agatacagag ccgatgctga gcgccgaaga caacaagctg ttgaccgagg
     4921 tggccgccga cacgcgcatg ggccagttgc tgcgccgcta ctggcatccc atcgccgcca
     4981 gctcccagct cgatgacaag caccccaccc gcctcgtcca cctgctgggc gagaagctgg
     5041 tcctctacaa ggacaagcag gggcggctgg gcctcatcga cgagcgctgc ccgcaccgcc
     5101 gcgcctccat gctctacggg attcccgagc aggagggcct gcgctgctcg taccacggct
     5161 ggctgttcaa caacgccggc cgctgcctgg cgcagccgta cgagcagatg gaggacccgt
     5221 gcagcaactt caaggaccac gtgcgcatca agtcctatcc cgtccgggag ctgggcgggc
     5281 tggtgttcgc gtacctgggg cccgcgcccg cgccggagct gcccgcgtgg gatttgctcg
     5341 tcacggagaa cctccaccgc gacatcggct tcgccgtggt gccctgcaac tggctgcaaa
     5401 tcatggagaa cgcggcggac cccgtgcacg ccgagtggct gcacggccac ttcgccaact
     5461 acgtctggga gcggctgggc aagcccgagc gcatcaagcc cttcccgacg cacaagaaga
     5521 ttggcttcga cctgagcgag tacggcatca tcaagcggcg cgtgctcgag ggggagacgg
     5581 aggagcacga gaactggaag ttcggccact cgctggtgtt ccccaacctc cagaagggcg
     5641 gcggcctgca gtggcgcgtg cccatggatg agacgcgcac gctgcacgtc tggtactaca
     5701 cgtacacgcc cgccgagggc accgtggtgc cgaaggacgc gcccatcccc gtcttcgacg
     5761 tgccggtgcc cgcgctggac gagcacggcc acccgcgctg ggacgtgctg gacttcaccg
     5821 ccggccagga catggtgatg tggtacacgc agggcgccgt cgccgagcgg tggaaggaga
     5881 cgctggggcg ctcggaccgc ggcgtcatca tgtaccgcaa cctgctcaag gcgaacctgg
     5941 agaagctggc ccggggcgag gagccgatga acgtcttccg cgacccggcg aaggcggcct
     6001 tcatccagct ggacacggag gagtcgagcg ggcggcggct gtactcggac cgggcgcggc
     6061 agtacggccc gtccagcagc aacggcccgg gcggcggcgc caccaagtac agcccggtgc
     6121 tcaacctgca caagggcgcg gagacggtgt ccgccaagga ggtcatgccg gagacggccc
     6181 tcccggccgc ccctcccgcc gcgcgcaagg agaccgcatg agcgccgccc gccagcgccc
     6241 gccgctcttg cccgagcggc agtggtcctc cagctacgtc tcctactgga gccccatgca
     6301 gggcggggac cggatgacct ccggccacgt ctggtacgac tacgggcggg gcgtctaccg
     6361 catcgacggc gtgctcaacc cctgggatga gcaggcccac ggccacctgc tgtggaagtc
     6421 ggaaatcaac cagttcggcg cgggcgagtg ccacacctgg gcggtggcct atgacgtgcc
     6481 gggcgaggcc gcgccgacgt accgcgcgcg gccgctcgcg tacgagcgca cgaagtcccc
     6541 cggctcgctc gtgccctgcg acgtgctggt gcgccacgag gccgtcttcg tgggcaccga
     6601 gcaggtgctg ggcttcgagg ccgagggctg gcgctacgag cgccccgagg gccgcgggcc
     6661 ggtgacgtac tacttccgcg ccggcacccg gcacctgctg cgcatggtca acggcgaccc
     6721 ccgcctccac gccgcaatcc gggacttccc gaccttcagc gagcagccca tccccgacac
     6781 cgtgttccag ccccacccct gggcggcgcg ctga
//
