BGC0000820: physostigmine biosynthetic gene cluster from Streptomyces griseofuscus
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Location: 1 - 8,547 nt. (total: 8,547 nt).
This entry is originally from NCBI GenBank KF201694.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000820
Short description physostigmine biosynthetic gene cluster from Streptomyces griseofuscus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Alkaloid
Loci NCBI GenBank: KF201694.1
Compounds
  • physostigmine
Species Streptomyces griseofuscus [taxonomy]
References
Chemical products information
physostigmine
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C15H21N3O2
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AHL44339.1
  • psmA
1 - 1008 (+) methyltransferase
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  • AHL44340.1
  • psmB
1097 - 2026 (+) hydrolase
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  • AHL44341.1
  • psmC
2060 - 2845 (+) methyltransferase
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  • AHL44342.1
  • psmD
2861 - 3664 (+) methyltransferase
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  • AHL44343.1
  • psmE
3668 - 5335 (+) carbamoyltransferase
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  • AHL44344.1
  • psmF
5332 - 5880 (+) N-acetyltransferase
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  • AHL44345.1
  • psmG
5864 - 7069 (+) putative tryptophan 2,3-dioxygenase
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  • AHL44346.1
  • psmH
7066 - 8547 (+) PLP-dependent decarboxylase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 4IL6M35C3LCTFERWKJH5IZTU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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