BGC0000843: alanylclavam biosynthetic gene cluster from Streptomyces clavuligerus ATCC 27064
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Location: 3,437,628 - 3,461,293 nt. (total: 23,666 nt).
This entry is originally from NCBI GenBank CM000913.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
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TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000843
Short description alanylclavam biosynthetic gene cluster from Streptomyces clavuligerus ATCC 27064
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Non-NRP beta-lactam)
Loci NCBI GenBank: CM000913.1
Compounds
  • alanylclavam
  • 2-hydroxymethylclavam
  • 2-formyloxymethylclavam
  • clavam-2-carboxylate
Species Streptomyces clavuligerus ATCC 27064 [taxonomy]
References
Chemical products information
alanylclavam
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C8H12N2O4
Chemical database entries
PubCHEM
ChemSpider
2-hydroxymethylclavam
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C6H9N1O3
Chemical database entries
PubCHEM
ChemSpider
2-formyloxymethylclavam
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C7H9N1O4
Chemical database entries
PubCHEM
clavam-2-carboxylate
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C6H7N1O4
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SCLAV_2920
  • EFG07991.1
 3437628 - 3439310 (-) Putative serine-threonine protein kinase
  • Activation / processing
Sequence-based prediction
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  • SCLAV_2921
  • EFG07992.1
  • cvm9
 3439374 - 3439922 (-) DNA-binding protein
  • Activation / processing
Sequence-based prediction
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  • SCLAV_2922
  • EFG07993.1
  • cvm6
 3440280 - 3441638 (-) Putative pyridoxal phosphate-dependent aminotransferase
  • Unknown
Sequence-based prediction
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  • SCLAV_2923
  • EFG07994.1
  • cvm5
 3441923 - 3443107 (+) Flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase
  • Scaffold biosynthesis
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  • SCLAV_2924
  • EFG07995.1
  • cvm4
 3443162 - 3444148 (+) Alpha/beta hydrolase
  • Unknown
Sequence-based prediction
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  • SCLAV_2925
  • EFG07996.1
  • cas1
 3444600 - 3445574 (-) Clavaminate synthase 1
  • Scaffold biosynthesis
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  • SCLAV_2926
  • EFG07997.1
  • cvm1
 3446153 - 3447187 (+) Aldo/keto reductase
  • Scaffold biosynthesis
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  • SCLAV_2927
  • EFG07998.1
  • cvm2
 3447624 - 3448079 (+) Hypothetical protein
  • Scaffold biosynthesis
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  • SCLAV_2928
  • EFG07999.1
  • cvm3
 3448076 - >3448586 (+) Flavin reductase-like protein
  • Precursor biosynthesis
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  • SCLAV_2929
  • EFG08000.1
  • cvm7
 3448733 - 3452077 (-) DnrI/RedD/AfsR-family transcriptional regulator
  • Activation / processing
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  • SCLAV_2930
  • EFG08001.1
  • cvm11
 3452469 - 3453119 (-) Putative translocator
  • Activation / processing
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  • SCLAV_2931
  • EFG08002.1
  • cvm12
 3453420 - 3454757 (+) Putative transcriptional regulatory protein
  • Activation / processing
Sequence-based prediction
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  • SCLAV_2932
  • EFG08003.1
  • cvm13
 3454884 - 3456056 (+) Beta-aspartyl-peptidase
  • Unknown
Sequence-based prediction
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  • SCLAV_2933
  • EFG08004.1
  • cvmH
 3457202 - 3458158 (+) LanU-like protein
  • Unknown
Sequence-based prediction
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  • SCLAV_2934
  • EFG08005.1
  • cvmP
 3458289 - 3460352 (-) putative protein-arginine deiminase
  • Unknown
Sequence-based prediction
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  • SCLAV_2935
  • EFG08006.1
  • cvmG
 3460571 - 3461293 (+) Hypothetical protein
  • Unknown
Sequence-based prediction
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: FHMX74FQXDJKCZZPHECQNTZR, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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