LOCUS       BGC0000961             36595 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Burkholderia thailandensis E264 chromosome II, complete sequence.
ACCESSION   BGC0000961
VERSION     BGC0000961
KEYWORDS    .
SOURCE      Burkholderia thailandensis E264
  ORGANISM  Burkholderia thailandensis E264
            Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
            Burkholderiaceae; Burkholderia; pseudomallei group.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 21:15:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1146
                     /codon_start=1
                     /locus_tag="BTH_II1222"
                     /note="identified by match to protein family HMM PF00903"
                     /product="4-hydroxyphenylpyruvate dioxygenase"
                     /protein_id="ABC34571.1"
                     /transl_table=11
                     /translation="MSSSASPASSDPAFAGPPGDNPLGMAGLEFVEFASREPDALARRF
                     EQLGFKAIARHVSKAVTLYRQGPMNFLVNAQPDSFAARYADEYGTGVCAIGIRVDDAQR
                     AFERAIELGAWAFEGERIGVGELTIPAIQGIGASHIHFVDRWRGRGGLRGGVGDISIFD
                     VDFRPIDVATAQADLDYFGAGLRRVDHLTQTVGRGRMQEWLDFYRDLLHFREIHELNAN
                     WHVSEEARVMVSPCGDVRIPVYEEGTRRTELMHEYLPDHPGEGVQHIALATDDILACAD
                     ALAANGVEFVEPPARYYDEIEARLPGCRIDVDALRARRILVDGEIGDDGVPRLFLQTFV
                     KRRPGEIFFEIVERRGHHGFGEGNLRALAHARNAARGALRQ"
     protocluster    1..36595
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[16499:21074]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      16500..21074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     protocluster    1..36595
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[12151:28542]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12152..28542
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     cand_cluster    1..36595
                     /SMILES="NCC(=O)CC(O)NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="interleaved"
                     /product="T1PKS"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..36595
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000961"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..36595
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /rules="Autoind_synth"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..15063
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4442:5063]"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      4443..5063
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="3"
     cand_cluster    1..15063
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="3"
                     /tool="antismash"
     gene            1..1146
                     /locus_tag="BTH_II1222"
     gene            complement(1136..1432)
                     /locus_tag="BTH_II1223"
     CDS             complement(1136..1432)
                     /NRPS_PKS="Domain: PCP (17-79). E-value: 8e-08. Score:
                     24.3. Matches aSDomain: nrpspksdomains_BTH_II1223_PCP.1"
                     /codon_start=1
                     /locus_tag="BTH_II1223"
                     /product="conserved hypothetical protein"
                     /protein_id="ABC36200.1"
                     /transl_table=11
                     /translation="MTIHVEVPHVQRIDDAVLAVVRAVLDRPDAAMHDAFLSIGGSLQA
                     AQRVVAQLQHRLCADIAPHLLLNSACIGDFADTLIRALNDGLGDASAPRPLTA"
     misc_feature    complement(1172..1174)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(1196..1381)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1223_PCP.1"
                     /evalue="8.00E-08"
                     /label="BTH_II1223_PCP.1"
                     /locus_tag="BTH_II1223"
                     /protein_end="79"
                     /protein_start="17"
                     /score="24.3"
                     /tool="antismash"
                     /translation="LAVVRAVLDRPDAAMHDAFLSIGGSLQAAQRVVAQLQHRLCADIA
                     PHLLLNSACIGDFADTL"
     gene            complement(1523..2446)
                     /locus_tag="BTH_II1224"
     CDS             complement(1523..2446)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1224"
                     /note="identified by match to protein family HMM PF05721;
                     match to protein family HMM TIGR01762"
                     /product="CmaB"
                     /protein_id="ABC35151.1"
                     /sec_met_domain="PhyH (E-value: 1.3e-42, bitscore: 136.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQFKLTPDEIARFREQGYIGPFKLYSEDEARDRYRQIRAQLFDR
                     EYAIYELPPNSPIANYDRHLDVNLLSEHIMRAEIVHKLNSILGPDLICWRSEMFPKYPG
                     DEGTDWHQADTFAHASGKPQVVWPGDGRFGGAVTVWTAFTDCDEENGCLRFMPGTHEEM
                     FYDESKKMTFDPSNINSLEKDGIKRGFFGYDYRSLQKDPDWKPDERNAVSIEMKPGEFV
                     IFWSTLMHSSFPNSTKDRTRLGYACRYVPAAVQIYPDTDTVSEYGSEVKLDKYGVVLVS
                     GEDSFRHNRQVTQNARGVPFVRHAAA"
     gene            complement(2592..2837)
                     /locus_tag="BTH_II1225"
     CDS             complement(2592..2837)
                     /NRPS_PKS="Domain: PP-binding (9-70). E-value: 4.8e-13.
                     Score: 41.3. Matches aSDomain:
                     nrpspksdomains_BTH_II1225_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1225"
                     /note="identified by match to protein family HMM PF00550"
                     /product="hypothetical phosphopantetheine-containing
                     protein"
                     /protein_id="ABC35825.1"
                     /sec_met_domain="PP-binding (E-value: 1.8e-13, bitscore:
                     41.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTIDITETIHNACRSVLGIPDLRSCEDFFERGVSSLTIVELQI
                     QIEQQLQRQVPTSKLMAAPTVEGWSQVYREAAATAS"
     aSDomain        complement(2628..2810)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1225_PP-binding.1"
                     /evalue="4.80E-13"
                     /label="BTH_II1225_PP-binding.1"
                     /locus_tag="BTH_II1225"
                     /protein_end="70"
                     /protein_start="9"
                     /score="41.3"
                     /tool="antismash"
                     /translation="TIHNACRSVLGIPDLRSCEDFFERGVSSLTIVELQIQIEQQLQRQ
                     VPTSKLMAAPTVEGWS"
     gene            complement(2855..4501)
                     /locus_tag="BTH_II1226"
     CDS             complement(2855..4501)
                     /NRPS_PKS="Domain: AMP-binding (59-454). E-value: 6.8e-101.
                     Score: 329.6. Matches aSDomain:
                     nrpspksdomains_BTH_II1226_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 382;
                     E-value: 6e-116)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1226"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM TIGR01733"
                     /product="peptide synthetase, putative"
                     /protein_id="ABC34137.1"
                     /sec_met_domain="AMP-binding (E-value: 9.8e-108, bitscore:
                     350.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSASSLPLRRPALRCATRKRPRPRDIGAASPHAPAVSSGPFASQ
                     NARESVTSISVNRLFSAQARLAPDALALSSGDTRLTYGELDRCANRLARRLADSGVRPR
                     DRVLLCVPRSADAVIAMLAVMKTGAAFVPVDPAYPDTIKRGYASDSGARHVLARAADAE
                     AFRHDGLCVLDIDDLSTGRDDQGPEVDAGHDGETPIYVMFTSGSTGRPKGVIVAHRGVA
                     RLVRQTNYIRITRDDTLLLLSPITFDASTFEIWGALLNGARLAIYEDATFDPNAVSRLI
                     AREKVSVMWLTAALFHLVARRFVGMLAGLRVVLAGGDVLNAAAIGAVFDAYPSITVING
                     YGPTENTTFTCCHVMTADRRPTDTVPIGRPITGTGVHILDAALREVPDGAEGELCASGL
                     GVALGYLNAPDATRAAFVDCPAAGGLLYRTGDRARRRADGVIEFLGRGDRLVKIRGYRV
                     SLDELQSVIAGIPGVEEAIVKVSEEATGEKRLSAIVQSGRAGPDMKAHVRRELAKRVPP
                     FQIPDDIQIFQHIPLNANGKLDRNRLPVSET"
     CDS_motif       complement(3113..3175)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1226_0004"
                     /evalue="4.60E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="BTH_II1226"
                     /protein_end="463"
                     /protein_start="442"
                     /score="25.4"
                     /tool="antismash"
                     /translation="FLGRGDRLVKIRGYRVSLDEL"
     aSDomain        complement(3140..4324)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1226_AMP-binding.1"
                     /evalue="6.80E-101"
                     /label="BTH_II1226_AMP-binding.1"
                     /locus_tag="BTH_II1226"
                     /protein_end="454"
                     /protein_start="59"
                     /score="329.6"
                     /specificity="consensus: val"
                     /tool="antismash"
                     /translation="FSAQARLAPDALALSSGDTRLTYGELDRCANRLARRLADSGVRPR
                     DRVLLCVPRSADAVIAMLAVMKTGAAFVPVDPAYPDTIKRGYASDSGARHVLARAADAE
                     AFRHDGLCVLDIDDLSTGRDDQGPEVDAGHDGETPIYVMFTSGSTGRPKGVIVAHRGVA
                     RLVRQTNYIRITRDDTLLLLSPITFDASTFEIWGALLNGARLAIYEDATFDPNAVSRLI
                     AREKVSVMWLTAALFHLVARRFVGMLAGLRVVLAGGDVLNAAAIGAVFDAYPSITVING
                     YGPTENTTFTCCHVMTADRRPTDTVPIGRPITGTGVHILDAALREVPDGAEGELCASGL
                     GVALGYLNAPDATRAAFVDCPAAGGLLYRTGDRARRRADGVIEFLGRGDRLVKIR"
     CDS_motif       complement(3254..3343)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1226_0003"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="BTH_II1226"
                     /protein_end="416"
                     /protein_start="386"
                     /score="36.3"
                     /tool="antismash"
                     /translation="PDGAEGELCASGLGVALGYLNAPDATRAAF"
     CDS_motif       complement(3848..3904)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1226_0002"
                     /evalue="2.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BTH_II1226"
                     /protein_end="218"
                     /protein_start="199"
                     /score="29.3"
                     /tool="antismash"
                     /translation="YVMFTSGSTGRPKGVIVAH"
     CDS_motif       complement(4097..4138)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1226_0001"
                     /evalue="2.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="BTH_II1226"
                     /protein_end="135"
                     /protein_start="121"
                     /score="17.4"
                     /tool="antismash"
                     /translation="LAVMKTGAAFVPVD"
     gene            complement(4443..5063)
                     /locus_tag="BTH_II1227"
     CDS             complement(4443..5063)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="BTH_II1227"
                     /note="identified by match to protein family HMM PF00765"
                     /product="N-acyl homoserine lactone synthase"
                     /protein_id="ABC34067.1"
                     /sec_met_domain="Autoind_synth (E-value: 4.7e-27, bitscore:
                     85.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTTVISAAQLDSTVKAALGNYRRAIFIEKLGWPLPLVDGLEID
                     QFDRPDTIYVVGKTESGDICGCARLLPTTKPYLLGEVFADLMGDAPPPCCADVWEISRF
                     SSSILSGGPDALQRAHRNTRILLAQIVHFAQAAGVKRLITVSPLAVERLLNRLKVHIHR
                     AGPPRLIDGKPVFACWIEVDDITLDALGVEPAASPAGAPLRHS"
     gene            complement(5147..5554)
                     /locus_tag="BTH_II1228"
     CDS             complement(5147..5554)
                     /codon_start=1
                     /locus_tag="BTH_II1228"
                     /product="conserved hypothetical protein"
                     /protein_id="ABC35966.1"
                     /transl_table=11
                     /translation="MAQRSAPASSAPAAAGQDGYVRLSLPQLARVSLAPTFAAADDQIL
                     SEIWDLGICALRAGYCEWSDAHWPAPTSLGWSWFVDVEKTLRIVPDSLASNLMIISAEG
                     YDLGPENTRRFLLDWIAKFDWRGLLAPLIQD"
     gene            6194..7426
                     /locus_tag="BTH_II1229"
     CDS             6194..7426
                     /codon_start=1
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 420.2; E-value:
                     1.3e-127)"
                     /gene_kind="transport"
                     /locus_tag="BTH_II1229"
                     /product="sodium/hydrogen exchanger"
                     /protein_id="ABC34499.1"
                     /transl_table=11
                     /translation="MVMWLLQLALIIAVCACFGWLAQRVGQSKVVGELAAGIALGPAAL
                     GAIDSNFYATVFGPGASTGMAQLGEVGVIALMFQIGLHMNLGGASTLRSLRTMPPAVVV
                     AGIGMLLPMAGGIAIGYLSHGALAPRIAALPYVLFCGVALSVSALPVMARIVMDMELVD
                     APPSLLALSAAMLTDLAGWIMLAFVSAIAVAGADASGPSHIVAGIAVFLLLAKLVARFV
                     VSPLAADAAKRASPAKLMSVVVPYVLVCAWATTAIGVHSAFGALLAAVMLRGVPGLQAQ
                     WERQMEGFVNAVLLPVFFVYSGLRVTFDSFDGASPWLWFVPFLCVAFVGKFGGAYLGAR
                     ICGMNRGDAALVGSLMNTRGLVELVVLSAGLQIHALSQSAYAVLLLVALTTTAMTTPFV
                     RLWRRAVLRPA"
     misc_feature    6206..6208
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7477..8334
                     /locus_tag="BTH_II1230"
     CDS             7477..8334
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1230"
                     /note="identified by Glimmer2; putative"
                     /product="hypothetical protein"
                     /protein_id="ABC35002.1"
                     /sec_met_domain="PF00561 (E-value: 1.5e-07, bitscore: 21.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRSIIADDGRELNAFVYGANPDAPAVVVVLPFGARHAMLSRFY
                     DALQSRFTVVTWESRFVLDVDRDDDDAGIAAQTHARDLASVIRATTGRGRNVPVDVVAY
                     CSGAGVALLAAHHHPDAISRIVLVSGEYLLPAAVAAPTDIQRQMDIFLSLAARSRAIAG
                     SIQEKIAAAQERGQTEFQAHLSEPFSSDLHLHRYGINYLSYRDVDMIEVAKQVSHPVLS
                     IVSTEDMHVGPAGSLEISRLLRRCVRNVSVAGDHYEICRGNADIVKSVVEFLDADEPTL
                     RETP"
     gene            complement(8433..9137)
                     /locus_tag="BTH_II1231"
     CDS             complement(8433..9137)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs)
                     SMCOG1197:autoinducer-binding transcriptional regulator,
                     (Score: 312.1; E-value: 3.4e-95)"
                     /gene_kind="regulatory"
                     /locus_tag="BTH_II1231"
                     /note="identified by match to protein family HMM PF00196;
                     match to protein family HMM PF03472"
                     /product="autoinducer-binding transcriptional regulator,
                     LuxR family"
                     /protein_id="ABC34774.1"
                     /transl_table=11
                     /translation="MHDFLQFWLNEFSRSENPQHVNSVLTRAAATLGYEYAAYGMRRPF
                     PISNPQILMVSNYPDRWQERYIEARFANVDSAVKAALGSDRPVTWSASTNASKSAFWAE
                     ALSFGIAHGWSSASRGADGTIGVLSLSRRQDAIDTAEKFRNESIVHWLANVAHASMAPF
                     LPAADEFDPDLTRRETDVLKWTADGKTAYEIALILSISESTVNFHVKNIVSKLGSTNKI
                     QAVAKAALMGML"
     gene            complement(9687..11768)
                     /locus_tag="BTH_II1232"
     CDS             complement(9687..11768)
                     /codon_start=1
                     /locus_tag="BTH_II1232"
                     /note="identified by match to protein family HMM PF01432"
                     /product="oligopeptidase A"
                     /protein_id="ABC35159.1"
                     /transl_table=11
                     /translation="MAPTTLVNPLLDRSQLPRFESIRDFHVSQAVDALLIDLDNAILRA
                     SAKNSPPNWVNVIEPISLALESLEYAWGTVTHLVSVCDSAPLRAAYGSCAGRVSAALSR
                     FRQNAALLDRYRAVAESDGFCALAPERRTVVRNLIRDARLAGSELPPGPRARLNVLRER
                     IAQLATAYQDNIADATRAFARIVTDDAELDGIPDYARAAARAAAARRAAEGFEFTLDFA
                     SYQQVMQFSTCRALREEMYRARSTRASELGATYANGAAQWDNAPVMAEMLKLRHEEAGL
                     LGYRDFAQMSLERKMARTPERACAFLENLHRRVSPKASLEWQALQSFARGELGLADVQP
                     WDIAFATERMRQQCFGVSTEDVRRYFPEHAVLRGLFDLVETLFDIRIRPDEGSVWHDDV
                     RLFRLEDLRGETVAHLYLDLYARDGKREGAWAASGRSRATGPDGSIRTPVAYLMCNVAA
                     PAAGSPACFAFDQVVTLFHEMGHCLHHMLTGVAESAISGTNGVEWDAIEFPSQFMENFC
                     WDPHVVSTLSAHVETGEPLPNTLFERMLAARHFNQGIEMAHQIALSMLDIALHSRQEID
                     SINSMQNTIHEIYQKYELTPLDRQARSANTFSHIFSGGYAAAYYSYQWAQVLAADAYAA
                     VEEASVERAEVGKREAGERYRTEVLEPGGSRPALESFIAFRGRAPSLDALLRHCRIDR"
     misc_feature    complement(10161..10163)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11721..11723)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11751..11753)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12152..16492
                     /locus_tag="BTH_II1233"
     CDS             12152..16492
                     /NRPS_PKS="Domain: Condensation_LCL (1-239). E-value:
                     2.5e-35. Score: 113.8. Matches aSDomain:
                     nrpspksdomains_BTH_II1233_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (405-789). E-value: 9.9e-92.
                     Score: 299.4. Matches aSDomain:
                     nrpspksdomains_BTH_II1233_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (903-963). E-value: 2.4e-13.
                     Score: 42.3. Matches aSDomain:
                     nrpspksdomains_BTH_II1233_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1021-1306). E-value:
                     1.6e-30. Score: 98.0. Matches aSDomain:
                     nrpspksdomains_BTH_II1233_Condensation_LCL.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     312.4; E-value: 7.3e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="BTH_II1233"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF00668; match to protein family HMM TIGR01733"
                     /product="peptide synthetase, putative"
                     /protein_id="ABC34305.1"
                     /sec_met_domain="Condensation (E-value: 6e-35, bitscore:
                     111.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-97, bitscore:
                     317.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.2e-14, bitscore:
                     42.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFIERAGVPVQYSESNPRGPLEFVDLSDVDPSVRQQRIDAAVQG
                     CLLAPFDLLAEPVHRFLLIRTRPRGYLLALNIHHVCVDGASALILLDDISSAYGDRAAY
                     AAASAARTGQGFDAVLNLERQRWADGVHAQTEAAWRAHLADRVCSVEFAKLAFDGDRPA
                     GDGARQYRWTLPDTLPARLKAVNRVTRTTPFVILMSAFSVLLHRYLQQDALAIAYPVDT
                     RPSGFARIFGSFINFVPAFVDVSPDMTADALFEKVRQQRRQTKAIADFPQVDLMRLARR
                     TLADSSSPCLNVALVPARFALDSLKLGGVRVEQRHYFVGSAKQDLALLYDGDDTLSLIL
                     EYRHGLLSESVARQMASDFNVIVEQIVDRPDLRIGDLALSDQHAFAERHATLADAAPQT
                     TAVAAIERALREQPTRIVAGEPGHAVSARQLSGASNGIARRLAAANVKAGDRVGVRMNR
                     GGALLAALLGIWKIGAAYVPLPTDLPPARRAHIADDAGLAACLHRTAPADPTSHDIVLT
                     DEIFAAPDAEALADIDADPDGIAYLIYTSGSTGVPKGVEVTHRNVASFLRAMAGALPIG
                     RDDRLLATTTIGFDISLLELLLPLTVGAAVIACPEHVRIDAKALERVIDDERITWLQGT
                     PSFFNVLRAGGWRGNKGLNILCGGEPIDASTYDFLRDACASVWQVYGPTEATIWSTIAG
                     PEADGVAGLGEPLRNTTIHLLDAHGQLVPRFSKGEICIGGHGVARGYRNRAALTAERFV
                     HVPGAGRVYRTGDFAFRDSHERLRFLGREDGQVKIRGFRVELGEIEKQIEALGEVRKAV
                     VLVQRATAAEPTLIAWCEPRAGRALEPDALRAALAAALPAYMVPARIARIDSWPLNANG
                     KIDRGALADRATAPTCPPQAPPLDALDALVPTFQAIYADVLRLDAVDPRATLMTLGGHS
                     LSAVRIIAQLRQKLNVDVGLETFMANSSIVGLIGSLRESGALGAADNGGGDGGRASPPE
                     AEGAAATSETVVPSAARPDASAASAPCVSARTLKPSASEKALYFLDSVSTVRQTYNIPV
                     GLHFPEGVNADALERALRHVLDTHESLRAAFEPTAEGLVKRIHPTPAGALIERHAPTDF
                     TTLRRTLNRMLREPFELHEGPLMRAHHFPLEEGGAAVFYLFHHIVVDGIGCGNFLREMA
                     GAYEAIRGGAQPVGDGASTGDDDDPPANAAARVDELISRFGIVDRVLNLPYRAPFPEVR
                     TLAGDSLALEIAADVRAELDEYSRAAGVPLATIFLSAFALTLHRLSGDRIVNVGLATMN
                     RTPRTLGKIGLYTNTIVLPVEIEPSSRLSDFVDRVTASLFSIYGYADVPFEEVASRLVE
                     YASLGRTPVFQTFFNFIDRSMYEFSMAGLPVREIALRPTGAKFELSLEVNDFRTHTQVF
                     FEYSQDVFDEALVDEIASEFVRSLLACVRSPGDAVERLALTTQS"
     aSDomain        12155..12868
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1233_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="2.50E-35"
                     /label="BTH_II1233_Condensation_LCL.1"
                     /locus_tag="BTH_II1233"
                     /protein_end="239"
                     /protein_start="1"
                     /score="113.8"
                     /tool="antismash"
                     /translation="RFIERAGVPVQYSESNPRGPLEFVDLSDVDPSVRQQRIDAAVQGC
                     LLAPFDLLAEPVHRFLLIRTRPRGYLLALNIHHVCVDGASALILLDDISSAYGDRAAYA
                     AASAARTGQGFDAVLNLERQRWADGVHAQTEAAWRAHLADRVCSVEFAKLAFDGDRPAG
                     DGARQYRWTLPDTLPARLKAVNRVTRTTPFVILMSAFSVLLHRYLQQDALAIAYPVDTR
                     PSGFARIFGSFINFVP"
     aSModule        12155..15040
                     /complete
                     /domains="nrpspksdomains_BTH_II1233_Condensation_LCL.1"
                     /domains="nrpspksdomains_BTH_II1233_AMP-binding.1"
                     /domains="nrpspksdomains_BTH_II1233_PP-binding.1"
                     /locus_tags="BTH_II1233"
                     /monomer_pairings="gly -> gly"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       12380..12445
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0001"
                     /evalue="2.10E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="BTH_II1233"
                     /protein_end="98"
                     /protein_start="76"
                     /score="17.2"
                     /tool="antismash"
                     /translation="IHHVCVDGASALILLDDISSAY"
     CDS_motif       12803..12868
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0002"
                     /evalue="2.00E+00"
                     /label="C5_LCL_267-296"
                     /locus_tag="BTH_II1233"
                     /protein_end="239"
                     /protein_start="217"
                     /score="1.1"
                     /tool="antismash"
                     /translation="YPVDTRPSGFARIFGSFINFVP"
     aSDomain        13367..14518
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1233_AMP-binding.1"
                     /evalue="9.90E-92"
                     /label="BTH_II1233_AMP-binding.1"
                     /locus_tag="BTH_II1233"
                     /protein_end="789"
                     /protein_start="405"
                     /score="299.4"
                     /specificity="consensus: gly"
                     /tool="antismash"
                     /translation="ERALREQPTRIVAGEPGHAVSARQLSGASNGIARRLAAANVKAGD
                     RVGVRMNRGGALLAALLGIWKIGAAYVPLPTDLPPARRAHIADDAGLAACLHRTAPADP
                     TSHDIVLTDEIFAAPDAEALADIDADPDGIAYLIYTSGSTGVPKGVEVTHRNVASFLRA
                     MAGALPIGRDDRLLATTTIGFDISLLELLLPLTVGAAVIACPEHVRIDAKALERVIDDE
                     RITWLQGTPSFFNVLRAGGWRGNKGLNILCGGEPIDASTYDFLRDACASVWQVYGPTEA
                     TIWSTIAGPEADGVAGLGEPLRNTTIHLLDAHGQLVPRFSKGEICIGGHGVARGYRNRA
                     ALTAERFVHVPGAGRVYRTGDFAFRDSHERLRFLGREDGQVKIR"
     CDS_motif       13550..13588
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0003"
                     /evalue="2.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="BTH_II1233"
                     /protein_end="479"
                     /protein_start="466"
                     /score="14.5"
                     /tool="antismash"
                     /translation="LGIWKIGAAYVPL"
     CDS_motif       13769..13828
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0004"
                     /evalue="1.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="BTH_II1233"
                     /protein_end="559"
                     /protein_start="539"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AYLIYTSGSTGVPKGVEVTH"
     CDS_motif       13985..14023
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0005"
                     /evalue="2.40E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="BTH_II1233"
                     /protein_end="624"
                     /protein_start="611"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="HVRIDAKALERVI"
     CDS_motif       14333..14407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0006"
                     /evalue="2.10E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="BTH_II1233"
                     /protein_end="752"
                     /protein_start="727"
                     /score="42.4"
                     /tool="antismash"
                     /translation="GEICIGGHGVARGYRNRAALTAERF"
     CDS_motif       14483..14548
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0007"
                     /evalue="9.70E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BTH_II1233"
                     /protein_end="799"
                     /protein_start="777"
                     /score="36.8"
                     /tool="antismash"
                     /translation="FLGREDGQVKIRGFRVELGEIE"
     aSDomain        14861..15040
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1233_PP-binding.1"
                     /evalue="2.40E-13"
                     /label="BTH_II1233_PP-binding.1"
                     /locus_tag="BTH_II1233"
                     /protein_end="963"
                     /protein_start="903"
                     /score="42.3"
                     /tool="antismash"
                     /translation="FQAIYADVLRLDAVDPRATLMTLGGHSLSAVRIIAQLRQKLNVDV
                     GLETFMANSSIVGLI"
     aSDomain        15215..16069
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1233_Condensation_LCL.2"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.60E-30"
                     /label="BTH_II1233_Condensation_LCL.2"
                     /locus_tag="BTH_II1233"
                     /protein_end="1306"
                     /protein_start="1021"
                     /score="98.0"
                     /tool="antismash"
                     /translation="LKPSASEKALYFLDSVSTVRQTYNIPVGLHFPEGVNADALERALR
                     HVLDTHESLRAAFEPTAEGLVKRIHPTPAGALIERHAPTDFTTLRRTLNRMLREPFELH
                     EGPLMRAHHFPLEEGGAAVFYLFHHIVVDGIGCGNFLREMAGAYEAIRGGAQPVGDGAS
                     TGDDDDPPANAAARVDELISRFGIVDRVLNLPYRAPFPEVRTLAGDSLALEIAADVRAE
                     LDEYSRAAGVPLATIFLSAFALTLHRLSGDRIVNVGLATMNRTPRTLGKIGLYTNTIVL
                     PVEI"
     CDS_motif       15278..15388
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0008"
                     /evalue="3.60E-11"
                     /label="C2_LCL_024-062"
                     /locus_tag="BTH_II1233"
                     /protein_end="1079"
                     /protein_start="1042"
                     /score="35.5"
                     /tool="antismash"
                     /translation="TYNIPVGLHFPEGVNADALERALRHVLDTHESLRAAF"
     CDS_motif       15593..15658
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0009"
                     /evalue="3.80E-06"
                     /label="C3_LCL_132-143"
                     /locus_tag="BTH_II1233"
                     /protein_end="1169"
                     /protein_start="1147"
                     /score="19.6"
                     /tool="antismash"
                     /translation="FHHIVVDGIGCGNFLREMAGAY"
     CDS_motif       15983..16057
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0010"
                     /evalue="3.40E-03"
                     /label="C5_LCL_267-296"
                     /locus_tag="BTH_II1233"
                     /protein_end="1302"
                     /protein_start="1277"
                     /score="10.0"
                     /tool="antismash"
                     /translation="VGLATMNRTPRTLGKIGLYTNTIVL"
     CDS_motif       16130..16228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1233_0011"
                     /evalue="3.20E-04"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="BTH_II1233"
                     /protein_end="1359"
                     /protein_start="1326"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YGYADVPFEEVASRLVEYASLGRTPVFQTFFNF"
     gene            16500..21074
                     /locus_tag="BTH_II1234"
     CDS             16500..21074
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (3-425). E-value:
                     1.7e-135. Score: 444.0. Matches aSDomain:
                     nrpspksdomains_BTH_II1234_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (510-783). E-value: 2.8e-79.
                     Score: 258.4. Matches aSDomain:
                     nrpspksdomains_BTH_II1234_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1120-1316). E-value: 6.9e-28.
                     Score: 89.6. Matches aSDomain:
                     nrpspksdomains_BTH_II1234_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (1403-1468). E-value: 1.7e-22.
                     Score: 71.3. Matches aSDomain:
                     nrpspksdomains_BTH_II1234_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 204.9; E-value:
                     3.5e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="BTH_II1234"
                     /note="identified by match to protein family HMM PF00109;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF00698; match to protein family HMM PF02801"
                     /product="JamP"
                     /protein_id="ABC34108.1"
                     /sec_met_domain="PP-binding (E-value: 1.1e-13, bitscore:
                     42.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-79, bitscore: 258.4,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1e-138, bitscore: 453.1,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQVALIGSRLRLPGADTVDAFWENILAGRDCIDSLSDAELLAAG
                     VDPAALSQPEYVKRAGVLADVDRFDYRFFGYTFREAQAIDPQQRVLLTLAHQLLEQVGA
                     SSRDVGVYTSIGFPHYLLNNLSAQAPGRVALSDVVFGNSGDCASTRIAYKLDLHGPAMS
                     IQSGCSSALMALHSARIAILTGQCRMALVGAAAIRTPQKEGYLYQRDGVLAKDGVCRPF
                     DARASGTVFTNGAVVLALKALSAAQRDGDDIIGVIRGSAINNDGQRKSGYTAPSVAGQS
                     EAIRRAYERSGIAPETIGYVETHGTGTALGDPIEIQALKDAYGGHGGASARCALGSTKA
                     NIGHTDVAAGLAGVLKAALCLKHAIKPALAGFERANPNLPLDGSPFYIPSAPEPWPDAP
                     GQPRRAAVSALGVGGSNAHVILEQAPGRDLSRRVDAGPLLISAQTPPALDALDARYDEA
                     LARQTLPSGDARYTSQLFRQHYPEKRAFVFEPSGGRRRVTPSGDWRHAQAALLFPGQGT
                     QYAGMGGALYARGGWFRAAFDDCADRFVREGCADPRELLNADEARIRDTAVLQPYLFAL
                     EYALGATLLAMRLPVAAAIGHSLGEYVAATLAGVFDLADAVAIVAIRSRIMSRAPRGAM
                     LAVLADEARVTAFLNDELSLCAVNSDTSCVVGGTEQAVDALAARVAQAQLASVRLPTSH
                     AFHSHLMEASSREFAAAFDGVSMRAPRFPIVSNLDGRADLPERFATAGYWVDHLRRPVR
                     FRDCLATLASLVPFGAWIEAGPGRSIANTFARLPLTDASCFPTMLPGHETVLFDTLAAQ
                     CWANGVDVDWTPLYGDARGNVVPLVPHPLDEISCWIDAPAKRSASDAAPEYQKQSDIDQ
                     WFYEYDWTTVPPRGDGAKPDEAAETAIADSVLLIGDASAEAALLAERVARDAASFFVVD
                     GAHPDVLDGRLAAIAAQAGSKQTRISRVLIVVPSRRDGAAAHRADSDDTETHDESGRAI
                     DAMLSMQRTFDALRNALPGKLDIALIAFSGVHADEARPSVGRAWIDSFATVVQQEFSRM
                     ICRTVHVDAAALAGGETDPEASRRSIDALARACLRHSGRFLRIRDGRLIERKLKRGGSS
                     AAPAPAAAPKSPRSVLVVGGAGNVGMIYAAFFSTVVGADVAIVSRSASAFSNALRDPSA
                     AADRALRRRKALYERMVAAGRRILFVDADATDPLQLERAAQSVADAFGSLDLVVHAAGA
                     PADMHYRTFDDTDVAYLDALVSPKLDVCANLHALTRALRIPRVMIVSSISATLGGIGLY
                     GYAASHSLLNAYAQSASSAACRWTVIDWDAWEFFKDTRDEANDDVGIDHYAISEQEGLS
                     VLERLHALDWPAHVVVASGDLIGRYRNWVLSERDETPAAQQIVAPRPLLKDELIAPRTR
                     TEAALAKLWGECIGVEPVGIRDNFFELGGHSLIALKLVDRINQTLDWDLSAVDMFKFPT
                     IERLADANAADDAVAPDAADGARDDAHDDAVPASAALDAGVHAQRRRHHYYQSRKHSME
                     SKSE"
     aSDomain        16509..17774
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1234_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="1.70E-135"
                     /label="BTH_II1234_PKS_KS.1"
                     /locus_tag="BTH_II1234"
                     /protein_end="425"
                     /protein_start="3"
                     /score="444.0"
                     /tool="antismash"
                     /translation="VALIGSRLRLPGADTVDAFWENILAGRDCIDSLSDAELLAAGVDP
                     AALSQPEYVKRAGVLADVDRFDYRFFGYTFREAQAIDPQQRVLLTLAHQLLEQVGASSR
                     DVGVYTSIGFPHYLLNNLSAQAPGRVALSDVVFGNSGDCASTRIAYKLDLHGPAMSIQS
                     GCSSALMALHSARIAILTGQCRMALVGAAAIRTPQKEGYLYQRDGVLAKDGVCRPFDAR
                     ASGTVFTNGAVVLALKALSAAQRDGDDIIGVIRGSAINNDGQRKSGYTAPSVAGQSEAI
                     RRAYERSGIAPETIGYVETHGTGTALGDPIEIQALKDAYGGHGGASARCALGSTKANIG
                     HTDVAAGLAGVLKAALCLKHAIKPALAGFERANPNLPLDGSPFYIPSAPEPWPDAPGQP
                     RRAAVSALGVGGSNAHVILEQAP"
     aSModule        16509..20903
                     /complete
                     /domains="nrpspksdomains_BTH_II1234_PKS_KS.1"
                     /domains="nrpspksdomains_BTH_II1234_PKS_AT.1"
                     /domains="nrpspksdomains_BTH_II1234_PKS_KR.1"
                     /domains="nrpspksdomains_BTH_II1234_PCP.1"
                     /locus_tags="BTH_II1234"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       16974..17021
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0001"
                     /evalue="1.10E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="BTH_II1234"
                     /protein_end="174"
                     /protein_start="158"
                     /score="11.6"
                     /tool="antismash"
                     /translation="GPAMSIQSGCSSALMA"
     CDS_motif       17397..17444
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0002"
                     /evalue="2.70E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BTH_II1234"
                     /protein_end="315"
                     /protein_start="299"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVETHGTGTALGDPIE"
     CDS_motif       18030..18080
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0003"
                     /evalue="1.80E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="BTH_II1234"
                     /protein_end="527"
                     /protein_start="510"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LFPGQGTQYAGMGGALY"
     aSDomain        18030..18848
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1234_PKS_AT.1"
                     /evalue="2.80E-79"
                     /label="BTH_II1234_PKS_AT.1"
                     /locus_tag="BTH_II1234"
                     /protein_end="783"
                     /protein_start="510"
                     /score="258.4"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGTQYAGMGGALYARGGWFRAAFDDCADRFVREGCADPREL
                     LNADEARIRDTAVLQPYLFALEYALGATLLAMRLPVAAAIGHSLGEYVAATLAGVFDLA
                     DAVAIVAIRSRIMSRAPRGAMLAVLADEARVTAFLNDELSLCAVNSDTSCVVGGTEQAV
                     DALAARVAQAQLASVRLPTSHAFHSHLMEASSREFAAAFDGVSMRAPRFPIVSNLDGRA
                     DLPERFATAGYWVDHLRRPVRFRDCLATLASLVPFGAWIEAGPGRSIANTF"
     CDS_motif       18276..18383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0004"
                     /evalue="1.10E-15"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="BTH_II1234"
                     /protein_end="628"
                     /protein_start="592"
                     /score="49.6"
                     /tool="antismash"
                     /translation="AAIGHSLGEYVAATLAGVFDLADAVAIVAIRSRIMS"
     CDS_motif       18726..18761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0005"
                     /evalue="1.70E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="BTH_II1234"
                     /protein_end="754"
                     /protein_start="742"
                     /score="15.0"
                     /tool="antismash"
                     /translation="YWVDHLRRPVRF"
     aSDomain        19860..20447
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1234_PKS_KR.1"
                     /evalue="6.90E-28"
                     /label="BTH_II1234_PKS_KR.1"
                     /locus_tag="BTH_II1234"
                     /protein_end="1316"
                     /protein_start="1120"
                     /score="89.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="SVLVVGGAGNVGMIYAAFFSTVVGADVAIVSRSASAFSNALRDPS
                     AAADRALRRRKALYERMVAAGRRILFVDADATDPLQLERAAQSVADAFGSLDLVVHAAG
                     APADMHYRTFDDTDVAYLDALVSPKLDVCANLHALTRALRIPRVMIVSSISATLGGIGL
                     YGYAASHSLLNAYAQSASSAACRWTVIDWDAWE"
     CDS_motif       20313..20393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1234_0006"
                     /evalue="7.80E-03"
                     /label="PKSI-KR_m4"
                     /locus_tag="BTH_II1234"
                     /protein_end="1298"
                     /protein_start="1271"
                     /score="8.8"
                     /tool="antismash"
                     /translation="SSISATLGGIGLYGYAASHSLLNAYAQ"
     aSDomain        20709..20903
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1234_PCP.1"
                     /evalue="1.70E-22"
                     /label="BTH_II1234_PCP.1"
                     /locus_tag="BTH_II1234"
                     /protein_end="1468"
                     /protein_start="1403"
                     /score="71.3"
                     /tool="antismash"
                     /translation="EAALAKLWGECIGVEPVGIRDNFFELGGHSLIALKLVDRINQTLD
                     WDLSAVDMFKFPTIERLADA"
     gene            20956..25068
                     /locus_tag="BTH_II1235"
     CDS             20956..25068
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (42-473). E-value:
                     1.2e-150. Score: 494.0. Matches aSDomain:
                     nrpspksdomains_BTH_II1235_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_DHt (515-768). E-value: 8.9e-08.
                     Score: 24.1. Matches aSDomain:
                     nrpspksdomains_BTH_II1235_PKS_DHt.1"
                     /NRPS_PKS="Domain: PKS_KR (993-1189). E-value: 4.1e-47.
                     Score: 152.3. Matches aSDomain:
                     nrpspksdomains_BTH_II1235_PKS_KR.1"
                     /NRPS_PKS="Domain: PP-binding (1292-1355). E-value:
                     1.8e-12. Score: 39.5. Matches aSDomain:
                     nrpspksdomains_BTH_II1235_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 249; E-value:
                     1.5e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1235"
                     /note="identified by match to protein family HMM PF00109;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF02801"
                     /product="JamP"
                     /protein_id="ABC35027.1"
                     /sec_met_domain="PP-binding (E-value: 6.9e-13, bitscore:
                     39.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 4.6e-155, bitscore:
                     507.0, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.6e-36, bitscore:
                     114.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTTTPCRRRLRSMRACTRSGVAITTTKAENTAWSRKVNNLDVAI
                     IGMSGAFPGASDVREFWRNLESGRCSLERYSEQELLDAGVDPAHLKSPKYVPVGGRMRD
                     IECFDNEFFGISNHDARLMDPQQRVFLQLAWHAFEDAGFVPGAHPGRVGVYAGVSLNSY
                     LHTVVFRSDEVDLDRDGQSILFGNLSDYLTTRLSYLLDLKGPSVNIQTACSTSLVAIHE
                     ACQGLLSYQADVALAGACSINVPNTRGYLYSQDSFFSPDGQVRAFDEQAAGTVFSNGAG
                     LVVLKRLEDALRDNDQIYAVLKASAVNNDGSDKVGYAAPSVSGQSAVIRDALHACEIRP
                     EQIQYVETHGTGTSLGDPIEIAALTQAYAADRRRGAAHRPAKCAIGSVKTNIGHIDVAA
                     GVAGVIKTALALRHKTLPASLGFEKANPRLGLENGPFYVNDRTQPWASDTLRVAAVSSF
                     GIGGTNAHAILEEAPVQDPLPATKPAYCLTLSARTAQSLEALRGSYLAFLSGDDLPSFA
                     DLCFTSNVGRKPFAHRIAIAASGAADAARRLADATAATSDGQPHRIVVSTPAADANATW
                     QAICGGDIDPREPLFEAADRYSAAELVAAYAALLVAQLRRLGLAAALRQPAHLPDSLVE
                     LLAPRRDDPLRELIAQAPADASQSDYPLTLSAESELRIGTRVHALGAPSLRGRFVAELL
                     AAGWAAGVPVDWASFHADEARRKTSLPAYAFAKKALWLSTATEAERRNRKIEDIGQWFY
                     KPTWRETAALAARTRRADEPADASVLVFSADRAHRLAAPWAAAARCLYVVPGAGFGELS
                     DDTYCIDPASEGDYQRLIETLAARGRLPRRVVHAWLAAEAAWDGTPANFANCQTLGLFS
                     LIFFARSLNRVTVGSAACSIVVAASQMAALTPREEVNPDKATVLGISRTLQKEYPFIDC
                     RIVDIASHELFGATDSAAQLGLEFLEPLTPENEIVVLRGARRWQTTYQRFAVPAKCEPD
                     VQARGVYVIFGGLGELGLNVAAHLASRAPCTLLLVNSKRFVARDEWPAWIDEHGADHPY
                     SKKIEKIREMEKAGATVLLQQCDVADAKRVDAVLDDARERHGVIHSVIHAAGRVENGMI
                     DNKDVRHFETVFEAKVYGTYNLLSYLKRHPVTKVILCSSMNSIIGGLGQIDNAAANAFV
                     DAVAQTSLAASLGDICSTNWGAVNAERLTRPNVLPQFADLSREHMRNHMTEREIAAVYD
                     RILHWNFGPRLVISTIDFDSVLEHWGEVSKVTELARLRHVAAEAGEQASARAPDDDGYA
                     YRSELHRFVETSWARILGVAHVDWDGVLLELGAHSLSAVQFVSMVKDRYDVSLHAMIIY
                     EIRTLGLLVEHIETKLLEKAAQLEVSQ"
     aSDomain        21082..22374
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1235_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="1.20E-150"
                     /label="BTH_II1235_PKS_KS.1"
                     /locus_tag="BTH_II1235"
                     /protein_end="473"
                     /protein_start="42"
                     /score="494.0"
                     /tool="antismash"
                     /translation="VAIIGMSGAFPGASDVREFWRNLESGRCSLERYSEQELLDAGVDP
                     AHLKSPKYVPVGGRMRDIECFDNEFFGISNHDARLMDPQQRVFLQLAWHAFEDAGFVPG
                     AHPGRVGVYAGVSLNSYLHTVVFRSDEVDLDRDGQSILFGNLSDYLTTRLSYLLDLKGP
                     SVNIQTACSTSLVAIHEACQGLLSYQADVALAGACSINVPNTRGYLYSQDSFFSPDGQV
                     RAFDEQAAGTVFSNGAGLVVLKRLEDALRDNDQIYAVLKASAVNNDGSDKVGYAAPSVS
                     GQSAVIRDALHACEIRPEQIQYVETHGTGTSLGDPIEIAALTQAYAADRRRGAAHRPAK
                     CAIGSVKTNIGHIDVAAGVAGVIKTALALRHKTLPASLGFEKANPRLGLENGPFYVNDR
                     TQPWASDTLRVAAVSSFGIGGTNAHAILEEAP"
     aSModule        21082..25020
                     /domains="nrpspksdomains_BTH_II1235_PKS_KS.1"
                     /domains="nrpspksdomains_BTH_II1235_PKS_DHt.1"
                     /domains="nrpspksdomains_BTH_II1235_PKS_KR.1"
                     /domains="nrpspksdomains_BTH_II1235_PP-binding.1"
                     /incomplete
                     /locus_tags="BTH_II1235"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       21565..21612
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1235_0001"
                     /evalue="8.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="BTH_II1235"
                     /protein_end="219"
                     /protein_start="203"
                     /score="17.8"
                     /tool="antismash"
                     /translation="GPSVNIQTACSTSLVA"
     CDS_motif       21988..22035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1235_0002"
                     /evalue="2.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BTH_II1235"
                     /protein_end="360"
                     /protein_start="344"
                     /score="13.4"
                     /tool="antismash"
                     /translation="YVETHGTGTSLGDPIE"
     CDS_motif       22111..22155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1235_0003"
                     /evalue="3.00E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="BTH_II1235"
                     /protein_end="400"
                     /protein_start="385"
                     /score="10.3"
                     /tool="antismash"
                     /translation="GSVKTNIGHIDVAAG"
     aSDomain        22501..23259
                     /aSDomain="PKS_DHt"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1235_PKS_DHt.1"
                     /evalue="8.90E-08"
                     /label="BTH_II1235_PKS_DHt.1"
                     /locus_tag="BTH_II1235"
                     /protein_end="768"
                     /protein_start="515"
                     /score="24.1"
                     /tool="antismash"
                     /translation="FADLCFTSNVGRKPFAHRIAIAASGAADAARRLADATAATSDGQP
                     HRIVVSTPAADANATWQAICGGDIDPREPLFEAADRYSAAELVAAYAALLVAQLRRLGL
                     AAALRQPAHLPDSLVELLAPRRDDPLRELIAQAPADASQSDYPLTLSAESELRIGTRVH
                     ALGAPSLRGRFVAELLAAGWAAGVPVDWASFHADEARRKTSLPAYAFAKKALWLSTATE
                     AERRNRKIEDIGQWFYKPTWRETAALAARTR"
     aSDomain        23935..24522
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1235_PKS_KR.1"
                     /evalue="4.10E-47"
                     /label="BTH_II1235_PKS_KR.1"
                     /locus_tag="BTH_II1235"
                     /protein_end="1189"
                     /protein_start="993"
                     /score="152.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="GVYVIFGGLGELGLNVAAHLASRAPCTLLLVNSKRFVARDEWPAW
                     IDEHGADHPYSKKIEKIREMEKAGATVLLQQCDVADAKRVDAVLDDARERHGVIHSVIH
                     AAGRVENGMIDNKDVRHFETVFEAKVYGTYNLLSYLKRHPVTKVILCSSMNSIIGGLGQ
                     IDNAAANAFVDAVAQTSLAASLGDICSTNWGAV"
     CDS_motif       23938..24027
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1235_0004"
                     /evalue="4.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="BTH_II1235"
                     /protein_end="1024"
                     /protein_start="994"
                     /score="22.4"
                     /tool="antismash"
                     /translation="VYVIFGGLGELGLNVAAHLASRAPCTLLLV"
     CDS_motif       24379..24468
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1235_0005"
                     /evalue="1.50E-09"
                     /label="PKSI-KR_m4"
                     /locus_tag="BTH_II1235"
                     /protein_end="1171"
                     /protein_start="1141"
                     /score="30.4"
                     /tool="antismash"
                     /translation="ILCSSMNSIIGGLGQIDNAAANAFVDAVAQ"
     aSDomain        24832..25020
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1235_PP-binding.1"
                     /evalue="1.80E-12"
                     /label="BTH_II1235_PP-binding.1"
                     /locus_tag="BTH_II1235"
                     /protein_end="1355"
                     /protein_start="1292"
                     /score="39.5"
                     /tool="antismash"
                     /translation="VETSWARILGVAHVDWDGVLLELGAHSLSAVQFVSMVKDRYDVSL
                     HAMIIYEIRTLGLLVEHI"
     gene            25108..28542
                     /locus_tag="BTH_II1236"
     CDS             25108..28542
                     /NRPS_PKS="Domain: AMP-binding (8-399). E-value: 5.9e-86.
                     Score: 280.4. Matches aSDomain:
                     nrpspksdomains_BTH_II1236_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (506-573). E-value: 2.2e-16. Score:
                     51.7. Matches aSDomain: nrpspksdomains_BTH_II1236_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (608-902). E-value:
                     1.8e-65. Score: 212.8. Matches aSDomain:
                     nrpspksdomains_BTH_II1236_Condensation_LCL.1"
                     /NRPS_PKS="Domain: PP-binding (1064-1133). E-value:
                     9.4e-10. Score: 30.8. Matches aSDomain:
                     nrpspksdomains_BTH_II1236_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     272.1; E-value: 1.7e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="BTH_II1236"
                     /note="identified by match to protein family HMM PF00501;
                     match to protein family HMM PF00550; match to protein
                     family HMM PF00668; match to protein family HMM TIGR01733"
                     /product="nonribosomal peptide synthetase, putative"
                     /protein_id="ABC34483.1"
                     /sec_met_domain="Condensation (E-value: 2.6e-48, bitscore:
                     155.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-91, bitscore:
                     295.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.7e-16, bitscore:
                     49.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSVFARFEQVCRSSPQAVALESGERRLTYAQLHDMVASIGARL
                     AAAGVTPGALLGIFLPRDVRLPAALLASLGSGAVYVPLTEKYPPERLREIIETHGIEHV
                     VTTDALASQLPASCGKIVLPAEGFEKADWLPAAVRPQNAPVYVVFTSGSTGTPKGVLIG
                     ERNLGNLIDWYRAAFSAEQRRSVLASTQITFDLSVFELICTLCTGSKVVIVENVLQLLD
                     DGAPCDVSLINTVPSAARELVRHRKFPAAARVVNLAGEALYQDLVDDIYETAPQVEQVF
                     NLYGPSEDTTYSTGHAVPRRAASRTVSIGRSLPGKHAHILADDLTPVAPGEVGEICLSG
                     EGVALGYLNDAKLTAEKFPTIGHGPLAGQRIYRTGDLGSFDGDGLLRYLGRADRQVKVR
                     GVRIEPGEIEVALRSIEGIADAAVVKVVDAANNDQLVALVVAQPSAPSANDVLDRLQTL
                     IPAYMVPSRVELIDAIPLNGNGKTDRTKLEQIAGALFGAAPSADDIQPRVAEIVAKLMS
                     RTDVAPDADFFRIGGNSLLSAQLTFMLQKQFSVTLSIADVFRHRTIDALAAIIRERSQK
                     AAKTAPAAAGQPPAATQSTPGSAGAADRIVFATPAQRGIWLLENSPGGRAVSNAPLVFD
                     YAGTLDRALLERCVAQLLERHAILRSNYVWEDGSLRIKCNARASFRIESVDLGSQTPDA
                     QRAKAGELVAREVMRPFDLRRDPMLRVTDIAFGERAGQLVFVFHHIAVDDRALNIVFSE
                     LQRLYNAGGDPTAIGAAPARQFADYAAAARDANARLGANLDYWRHKLADYRGATPYLVD
                     AQAKPASRFAGRLHFHSVAQDVSRNLEAGAARRGLTPFALFAAAVACIVHRASGSDDVT
                     IGTFFSNRDHFQDNELVGFFVNTLPLRMRIDSGWDVDQLAQAVSATLADAHSHRDVATE
                     DVFDALRINNTLRRAAFRVMVNLEPEQAEVLTMGALTARRALLDRHVAKYDLLFSLRKE
                     DGDYRVLVEYNTDLYDGDVIARVCANLDRALAALTGATRERLAAIALPNPLEPGEPGGE
                     AADAKPKAAADLDLRAVVRDIWASEVGNRTFGDDENFFDVGGSSLKIMTVYEKLSSFLK
                     DNGFEKEIDIVDLFEHVTVATLTDFLGELIEHDALAQ"
     aSDomain        25132..26304
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1236_AMP-binding.1"
                     /evalue="5.90E-86"
                     /label="BTH_II1236_AMP-binding.1"
                     /locus_tag="BTH_II1236"
                     /protein_end="399"
                     /protein_start="8"
                     /score="280.4"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="FEQVCRSSPQAVALESGERRLTYAQLHDMVASIGARLAAAGVTPG
                     ALLGIFLPRDVRLPAALLASLGSGAVYVPLTEKYPPERLREIIETHGIEHVVTTDALAS
                     QLPASCGKIVLPAEGFEKADWLPAAVRPQNAPVYVVFTSGSTGTPKGVLIGERNLGNLI
                     DWYRAAFSAEQRRSVLASTQITFDLSVFELICTLCTGSKVVIVENVLQLLDDGAPCDVS
                     LINTVPSAARELVRHRKFPAAARVVNLAGEALYQDLVDDIYETAPQVEQVFNLYGPSED
                     TTYSTGHAVPRRAASRTVSIGRSLPGKHAHILADDLTPVAPGEVGEICLSGEGVALGYL
                     NDAKLTAEKFPTIGHGPLAGQRIYRTGDLGSFDGDGLLRYLGRADRQVKVR"
     aSModule        25132..26826
                     /complete
                     /domains="nrpspksdomains_BTH_II1236_AMP-binding.1"
                     /domains="nrpspksdomains_BTH_II1236_PCP.1"
                     /locus_tags="BTH_II1236"
                     /monomer_pairings="ala -> ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25543..25593
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0001"
                     /evalue="4.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="BTH_II1236"
                     /protein_end="162"
                     /protein_start="145"
                     /score="25.4"
                     /tool="antismash"
                     /translation="YVVFTSGSTGTPKGVLI"
     CDS_motif       26095..26181
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0002"
                     /evalue="2.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="BTH_II1236"
                     /protein_end="358"
                     /protein_start="329"
                     /score="42.2"
                     /tool="antismash"
                     /translation="PGEVGEICLSGEGVALGYLNDAKLTAEKF"
     CDS_motif       26269..26334
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0003"
                     /evalue="8.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="BTH_II1236"
                     /protein_end="409"
                     /protein_start="387"
                     /score="37.0"
                     /tool="antismash"
                     /translation="YLGRADRQVKVRGVRIEPGEIE"
     aSDomain        26626..26826
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1236_PCP.1"
                     /evalue="2.20E-16"
                     /label="BTH_II1236_PCP.1"
                     /locus_tag="BTH_II1236"
                     /protein_end="573"
                     /protein_start="506"
                     /score="51.7"
                     /tool="antismash"
                     /translation="RVAEIVAKLMSRTDVAPDADFFRIGGNSLLSAQLTFMLQKQFSVT
                     LSIADVFRHRTIDALAAIIRER"
     aSDomain        26932..27813
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1236_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.80E-65"
                     /label="BTH_II1236_Condensation_LCL.1"
                     /locus_tag="BTH_II1236"
                     /protein_end="902"
                     /protein_start="608"
                     /score="212.8"
                     /tool="antismash"
                     /translation="TPAQRGIWLLENSPGGRAVSNAPLVFDYAGTLDRALLERCVAQLL
                     ERHAILRSNYVWEDGSLRIKCNARASFRIESVDLGSQTPDAQRAKAGELVAREVMRPFD
                     LRRDPMLRVTDIAFGERAGQLVFVFHHIAVDDRALNIVFSELQRLYNAGGDPTAIGAAP
                     ARQFADYAAAARDANARLGANLDYWRHKLADYRGATPYLVDAQAKPASRFAGRLHFHSV
                     AQDVSRNLEAGAARRGLTPFALFAAAVACIVHRASGSDDVTIGTFFSNRDHFQDNELVG
                     FFVNTLPLRMRID"
     aSModule        26932..28506
                     /domains="nrpspksdomains_BTH_II1236_Condensation_LCL.1"
                     /domains="nrpspksdomains_BTH_II1236_PP-binding.1"
                     /incomplete
                     /locus_tags="BTH_II1236"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       26992..27102
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0004"
                     /evalue="3.20E-10"
                     /label="C2_DCL_024-062"
                     /locus_tag="BTH_II1236"
                     /protein_end="665"
                     /protein_start="628"
                     /score="32.3"
                     /tool="antismash"
                     /translation="NAPLVFDYAGTLDRALLERCVAQLLERHAILRSNYVW"
     CDS_motif       27316..27381
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0005"
                     /evalue="1.50E-05"
                     /label="C3_LCL_132-143"
                     /locus_tag="BTH_II1236"
                     /protein_end="758"
                     /protein_start="736"
                     /score="17.6"
                     /tool="antismash"
                     /translation="FHHIAVDDRALNIVFSELQRLY"
     CDS_motif       27712..27801
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0006"
                     /evalue="1.80E-10"
                     /label="C5_LCL_267-296"
                     /locus_tag="BTH_II1236"
                     /protein_end="898"
                     /protein_start="868"
                     /score="33.2"
                     /tool="antismash"
                     /translation="DVTIGTFFSNRDHFQDNELVGFFVNTLPLR"
     CDS_motif       27790..27858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1236_0007"
                     /evalue="3.20E-01"
                     /label="C2_LCL_024-062"
                     /locus_tag="BTH_II1236"
                     /protein_end="917"
                     /protein_start="894"
                     /score="3.5"
                     /tool="antismash"
                     /translation="LPLRMRIDSGWDVDQLAQAVSAT"
     aSDomain        28300..28506
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1236_PP-binding.1"
                     /evalue="9.40E-10"
                     /label="BTH_II1236_PP-binding.1"
                     /locus_tag="BTH_II1236"
                     /protein_end="1133"
                     /protein_start="1064"
                     /score="30.8"
                     /tool="antismash"
                     /translation="VVRDIWASEVGNRTFGDDENFFDVGGSSLKIMTVYEKLSSFLKDN
                     GFEKEIDIVDLFEHVTVATLTDFL"
     gene            28583..30922
                     /locus_tag="BTH_II1237"
     CDS             28583..30922
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (2-427). E-value:
                     2.2e-150. Score: 493.1. Matches aSDomain:
                     nrpspksdomains_BTH_II1237_PKS_KS.1"
                     /NRPS_PKS="Domain: PCP (684-751). E-value: 1.9e-09. Score:
                     29.5. Matches aSDomain: nrpspksdomains_BTH_II1237_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 229.2; E-value:
                     1.5e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1237"
                     /note="identified by match to protein family HMM PF00109;
                     match to protein family HMM PF02801"
                     /product="thiotemplate mechanism natural product
                     synthetase"
                     /protein_id="ABC34154.1"
                     /sec_met_domain="PP-binding (E-value: 2.1e-08, bitscore:
                     25.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 8.2e-151, bitscore:
                     493.1, seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIAIVGVSARVPGARDVDALWSLLMSGGDGLTTFEPHELAAELA
                     PLGDAERARYVPRRGVLDGIEACDAGFFNLSAAEATLLDPQHRVLMELVWEALEDAGAA
                     DCAGRNVGVFTTSGLSHYLIKHLLPDPAISERHGQLQLLMLNDKDFLATRIAYFLNVHG
                     PAVNVQTGCSSSLVALHYACLSLLRRDCEMAVVGGVSIALPQQAGYVFSENMIGSRDGF
                     CRAFDSDASGTVRGNGACAVVLKPLAEALADRDPVWAVIKGTALNNDGRDKVGFTAPSP
                     KWQADVIDAVYRRSGVALDDVDFVEAHGTGTPLGDPIEARAINQVFARAGARRPRYLGA
                     LKTQIGHLDTAAGLAGLIKLCVALRNGTIPPTSHFRTLNPRISLDDSQFTINTEPVAWP
                     RRDAPRYAALSSFGIGGTNAHVVVADAPAGERAPAAGSAASVESAESGPHLIVVSAKSA
                     ASLDALRNAYADAIAALDDAALADFAYSTRVGRRGFEHRLAVCADGRADAVEQLRAARA
                     RFTAKTVEGVSVAAADAPSIAARLGIASPERAERPVEAIAARLAELGVAIDAGAAVRLG
                     IADGRLHVVTPDAWSEAIDAATPDATGRHLQAALWRAGVAVDFGRDTGSAARRRIRIPT
                     YRFDRQRHWIDAPCSRHGDGRDSQSAGDAAPDARRRMPPAEQPTSLVALEAALLSHWRG
                     LLGLPTLRSTDNVFEQGADSLTVAQFVAQLTSERALPVHVVDCYSEPSVGGQARLVGAR
                     IGLGGPAAAAAQASAPAPEVERFDNL"
     aSDomain        28589..29863
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1237_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="2.20E-150"
                     /label="BTH_II1237_PKS_KS.1"
                     /locus_tag="BTH_II1237"
                     /protein_end="427"
                     /protein_start="2"
                     /score="493.1"
                     /tool="antismash"
                     /translation="IAIVGVSARVPGARDVDALWSLLMSGGDGLTTFEPHELAAELAPL
                     GDAERARYVPRRGVLDGIEACDAGFFNLSAAEATLLDPQHRVLMELVWEALEDAGAADC
                     AGRNVGVFTTSGLSHYLIKHLLPDPAISERHGQLQLLMLNDKDFLATRIAYFLNVHGPA
                     VNVQTGCSSSLVALHYACLSLLRRDCEMAVVGGVSIALPQQAGYVFSENMIGSRDGFCR
                     AFDSDASGTVRGNGACAVVLKPLAEALADRDPVWAVIKGTALNNDGRDKVGFTAPSPKW
                     QADVIDAVYRRSGVALDDVDFVEAHGTGTPLGDPIEARAINQVFARAGARRPRYLGALK
                     TQIGHLDTAAGLAGLIKLCVALRNGTIPPTSHFRTLNPRISLDDSQFTINTEPVAWPRR
                     DAPRYAALSSFGIGGTNAHVVVADAP"
     aSModule        28589..30835
                     /domains="nrpspksdomains_BTH_II1237_PKS_KS.1"
                     /domains="nrpspksdomains_BTH_II1237_PCP.1"
                     /incomplete
                     /locus_tags="BTH_II1237"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       29069..29116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1237_0001"
                     /evalue="1.30E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="BTH_II1237"
                     /protein_end="178"
                     /protein_start="162"
                     /score="17.4"
                     /tool="antismash"
                     /translation="GPAVNVQTGCSSSLVA"
     CDS_motif       29204..29257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1237_0002"
                     /evalue="4.20E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="BTH_II1237"
                     /protein_end="225"
                     /protein_start="207"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="GYVFSENMIGSRDGFCRA"
     CDS_motif       29258..29296
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1237_0003"
                     /evalue="2.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="BTH_II1237"
                     /protein_end="238"
                     /protein_start="225"
                     /score="11.0"
                     /tool="antismash"
                     /translation="FDSDASGTVRGNG"
     CDS_motif       29492..29539
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1237_0004"
                     /evalue="1.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="BTH_II1237"
                     /protein_end="319"
                     /protein_start="303"
                     /score="14.2"
                     /tool="antismash"
                     /translation="FVEAHGTGTPLGDPIE"
     CDS_motif       29921..29959
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1237_0005"
                     /evalue="8.00E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="BTH_II1237"
                     /protein_end="459"
                     /protein_start="446"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="GPHLIVVSAKSAA"
     aSDomain        30635..30835
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1237_PCP.1"
                     /evalue="1.90E-09"
                     /label="BTH_II1237_PCP.1"
                     /locus_tag="BTH_II1237"
                     /protein_end="751"
                     /protein_start="684"
                     /score="29.5"
                     /tool="antismash"
                     /translation="EAALLSHWRGLLGLPTLRSTDNVFEQGADSLTVAQFVAQLTSERA
                     LPVHVVDCYSEPSVGGQARLVG"
     gene            30935..32527
                     /locus_tag="BTH_II1238"
     CDS             30935..32527
                     /codon_start=1
                     /locus_tag="BTH_II1238"
                     /product="polyketide synthase"
                     /protein_id="ABC35075.1"
                     /transl_table=11
                     /translation="MTSQYFLKKNVKIEPLVNRWHANPWLVYPPTAAYLMRHHLDIMTS
                     FVKHAALHEKAAGSRKIRGGPFVQGLGADDVPAMEALIEATRRDGAHLFGLADDLDALR
                     AALGAADGHSLVPFYEQVPPRLRGMVELAYQAGNHAYARLMEGLYYDAYDTSALQSFAL
                     APLWDDSRPFCLSTPRLDTSGDVLLDIPFADPLAVALTASRRNGLTPAQFEAILDRRSK
                     GTRADAVAALFSDAAPEHRPAEAHEPRVRYFGHACVLVQTGTENLLFDPLISYPFPGQS
                     PRFTFDDLPDVIDYVVITHSHHDHFVLETLLQIRDRVKTIVVPQNTHGQLMDPSLKHAA
                     HALGFENVIMMSEFDTLKLGGGKLHAVPFLGEHGDLDIRSKLGFLVEAGDRRVLMVADS
                     NNLDDRLYEHIRRRYGKVDLLFIGMECEGAPVSWLYGPMLNTKLARSMDDSRRLNGSGS
                     SAGFRLAEIVGADRVFIYAMAQEPWLTFISSLEYDESSFAMREARKMIDACRQANVDAC
                     LLNGCVDIPLRAR"
     gene            32532..33377
                     /locus_tag="BTH_II1239"
     CDS             32532..33377
                     /codon_start=1
                     /locus_tag="BTH_II1239"
                     /note="identified by match to protein family HMM PF00583"
                     /product="acetyltransferase, GNAT family"
                     /protein_id="ABC34220.1"
                     /transl_table=11
                     /translation="MDRAHRESASPVETLLDGMIGKNAYFPRRIGGAMRVHALGDHAVV
                     NSGLATDTFNLVISRAADGAQANAVAPIARDFDEAGLPAAWWTCRSGPDAAFSRALGDA
                     GFVDDETSVGMLAELDALPCVEPPRGFRVRQISEAGDVARFGALICALFDPPDPFVDAF
                     YLHVAALEIDTAEPLKLFIGEIDGRAVSTAALYLDAGTAHVFDISTAAHARRRGYARAI
                     THFVLAHARDRLGADRAALQASPEGLNVYRRLGFRPVCEFRVYSNRAAVLERSHDQHPR
                     "
     gene            33358..34200
                     /locus_tag="BTH_II1240"
     CDS             33358..34200
                     /NRPS_PKS="Domain: Thioesterase (44-269). E-value: 4.5e-40.
                     Score: 130.3. Matches aSDomain:
                     nrpspksdomains_BTH_II1240_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 230.7; E-value: 2.2e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1240"
                     /note="identified by match to protein family HMM PF00975"
                     /product="thioesterase II of alpha/beta hydrolase
                     superfamily"
                     /protein_id="ABC35463.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5e-09, bitscore:
                     27.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIPVRLDQFPPAADPAAPAAAFPAPAAKAAIRTLVAPSPGGAH
                     VLCIPWAGASIERFFAWKRHLPAGVGLSGVQLPGRGARAHEPSPTDLVALLDEIAAEYL
                     ALPDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLVVSGLSAPSVIAEEKRIA
                     HLDDDAFSAEVHALNGMPPEIARSPESLRYFMAVLRCDFRLYESYSFDADRPPLRCPIA
                     VCSGRDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAAMLGLALDAESTLVG"
     aSDomain        33490..34164
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BTH_II1240_Thioesterase.1"
                     /evalue="4.50E-40"
                     /label="BTH_II1240_Thioesterase.1"
                     /locus_tag="BTH_II1240"
                     /protein_end="269"
                     /protein_start="44"
                     /score="130.3"
                     /tool="antismash"
                     /translation="HVLCIPWAGASIERFFAWKRHLPAGVGLSGVQLPGRGARAHEPSP
                     TDLVALLDEIAAEYLALPDPPRILFGHSFGALIAFEIATRVSRAAGQAGGDPFVRLVVS
                     GLSAPSVIAEEKRIAHLDDDAFSAEVHALNGMPPEIARSPESLRYFMAVLRCDFRLYES
                     YSFDADRPPLRCPIAVCSGRDDPSVSEHGLNAWAALTTGECRRHDFDGDHFFIADHAAA
                     MLG"
     CDS_motif       33676..33744
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_BTH_II1240_0001"
                     /evalue="5.00E-08"
                     /label="NRPS-te1"
                     /locus_tag="BTH_II1240"
                     /protein_end="129"
                     /protein_start="106"
                     /score="25.4"
                     /tool="antismash"
                     /translation="PDPPRILFGHSFGALIAFEIATR"
     gene            34261..35487
                     /locus_tag="BTH_II1241"
     CDS             34261..35487
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 75.7; E-value: 4.4e-23)"
                     /gene_kind="transport"
                     /locus_tag="BTH_II1241"
                     /note="identified by match to protein family HMM PF07690"
                     /product="drug resistance transporter, Bcr/CflA family
                     protein, putative"
                     /protein_id="ABC36044.1"
                     /transl_table=11
                     /translation="MSETSKRHPSLVLILIPVVMLGQLSMDMYLPALGSLQASMRATGS
                     ELQMTLSAFVVSLGVSQFLVGEFARRAGRGRAIRIALVGFVCATAGCAVTSSIALFIVC
                     RAVQGIAAAVCVALSYAVIADNAKDSHESMRGMTMLTVASTVAPLIAPVAGSQVLQLAG
                     SWRAVFMLLLCVAIVAVLAFFAQPAARFDARAHDASKPARKIYLGIVTSSQFWRYALLC
                     SIGTTINFCFFSFLPGILLVQNGLTQNQFSAAFFLCGLTEIAGSLLAPRISKLIGPPGL
                     AGLACVCCALGGFGVAYFSTTPNAVVPIVAAFSIVELGTGMLIAPCFSAALYLFRSTSN
                     EASAICGFQQFMIAAGVATFAAAMKWQSSYALGILIGVAALIGAALCGTLPGGAQADEQ
                     TAGVPLNSD"
     gene            complement(35750..36595)
                     /locus_tag="BTH_II1242"
     CDS             complement(35750..36595)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121:dioxygenase, TauD/TfdA (Score: 351.5; E-value:
                     4.9e-107)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="BTH_II1242"
                     /note="identified by match to protein family HMM PF02668"
                     /product="dioxygenase, TauD/TfdA family"
                     /protein_id="ABC36162.1"
                     /transl_table=11
                     /translation="MISRKLSPALGAEIRGIDFSQPLSSQTRDDIIGLLSEHQLLVFPG
                     QRLSCEQQVAACRDFGELEPHPMTTNTSSFPEMTIVSNVTTDGKPVGYPTPPFELWHSD
                     LCYLEHPAKMTFFYAESVPDAHGDTWFANMFAAYETLPDELKSAIDGRNAIFSLDSSLV
                     KRCRKIGFDLNIAEDDFKPTVSHPAVRTHPHTRRRSIFVNWAHTDRIEGYSHEESDEIL
                     DRIFAHCRNEDFIYRHRYTNEDLVIWDNASLIHTNSPNPPVGNRIMRRVMVSGPKPFYQ
                     "
ORIGIN
        1 atgtccagct cagccagtcc cgcgtccagc gatcccgcgt ttgccggccc gccgggcgac
       61 aacccgctcg gcatggcggg gctcgaattc gtcgaattcg cgtcgcgcga gcctgacgcg
      121 ctcgcgcggc gcttcgagca gctcggtttc aaggcgatcg cgcggcacgt cagcaaggcg
      181 gtcacgctct accggcaagg gccgatgaac tttctcgtga acgcgcagcc cgattcgttc
      241 gccgcgcgct acgcggacga atatggcacg ggcgtgtgtg cgatcggcat tcgcgtcgac
      301 gacgcgcagc gcgcgttcga gcgcgcgatc gagctcggcg cgtgggcgtt cgagggcgag
      361 cggatcggcg tcggcgaatt gacgattccg gcgatccagg ggatcggcgc gtcgcacatc
      421 catttcgtcg accgctggcg cgggcgcggc ggattgcgcg gcggggtcgg cgacatctcg
      481 atcttcgacg tcgatttccg cccgatcgac gtcgccacgg cgcaggcgga cctcgactac
      541 ttcggcgccg gcctgcggcg cgtcgatcac ctgacgcaga cggtcggccg tggccggatg
      601 caggagtggc tcgatttcta tcgcgatctg ctgcacttcc gcgagatcca tgaactcaac
      661 gcgaactggc acgtgtcgga ggaggcgcgc gtgatggtgt cgccgtgcgg cgacgtgcgg
      721 attccggtgt acgaggaggg cacgaggcgc accgagctga tgcacgagta tctgcccgac
      781 catccgggcg agggggtgca gcacatcgcg ctcgcgaccg acgacattct cgcgtgcgcg
      841 gacgcgctcg cggcgaacgg cgtcgagttc gtcgagccgc ccgcgcgcta ctacgacgag
      901 atcgaggcgc gattgcccgg ctgccggatc gacgtcgatg cgctgcgcgc gcgccgcatt
      961 ctcgtcgacg gcgagatcgg cgacgacggc gtgccgaggc tgtttctcca gacgttcgtc
     1021 aagcgccggc ccggcgagat cttcttcgag atcgtcgagc ggcgcgggca tcacggcttc
     1081 ggcgagggca atctgcgcgc gctcgcgcac gcgaggaatg cggcgcgcgg cgcgctcagg
     1141 cagtgagcgg tcgcggcgcg cttgcgtcgc ctaagccgtc gttcagcgcg cggatcagcg
     1201 tgtcggcgaa atcgccgatg cacgcgctgt tcagcagcag atgcggcgcg atgtccgcgc
     1261 agagccggtg ctggagctgc gcgaccacgc gctgcgcggc ctgaagcgat ccgccgatcg
     1321 acaagaacgc gtcgtgcatc gcggcatccg ggcgatcgag cacggcccgg acgacggcga
     1381 gcaccgcgtc gtcgatacgc tggacatgcg gaacttcgac gtggatcgtc atggtcttcc
     1441 tccgaagaaa aaacggggag cggcggctcc ccgtaggcgg ttcccagtat ccgcgcggcg
     1501 agtgcttcgg gctcgcgcgg gattacgcgg cggcgtggcg gacgaacggc acgccgcgcg
     1561 cgttttgcgt gacctgacgg ttgtgccgga agctgtcctc gccggacacg agcacgacgc
     1621 cgtacttgtc gagcttcact tcgctgccgt actcgctgac ggtatcggta tccgggtaga
     1681 tctggaccgc cgcgggcacg taccggcacg cgtagccgag gcgagtgcga tccttcgtcg
     1741 agttggggaa cgacgagtgc atcagcgtcg accagaagat cacgaactcg cccggcttca
     1801 tctcgatcga cacggcgttg cgctcgtccg gcttccagtc cgggtccttc tgcaggctgc
     1861 ggtagtcgta gccgaagaag ccgcgcttga tcccgtcctt ctcgagcgag ttgatgttcg
     1921 acgggtcgaa ggtcatcttc ttcgattcgt cgtagaacat ctcctcgtgc gtgccgggca
     1981 tgaagcgcag gcagccgttt tcctcgtcgc aatcggtgaa cgccgtccac accgtcaccg
     2041 cgccgccgaa acggccgtcg ccgggccaca ccacctgcgg cttgcccgac gcgtgcgcga
     2101 acgtgtcggc ctggtgccag tcggtgccct cgtcgcccgg atatttcggg aacatttccg
     2161 agcgccagca gatgaggtcc gggcccagga tcgaattgag cttgtgcacg atctccgcac
     2221 gcatgatgtg ctcgctcagc agattcacgt cgagatgccg atcgtagttc gcgatcgggc
     2281 tgttcggcgg caattcgtag atcgcgtatt cgcggtcgaa cagttgcgcg cggatctggc
     2341 ggtagcgatc ccgcgcttcg tcctccgaat agagtttgaa cggtccgata tagccctgct
     2401 cgcggaagcg ggcgatctcg tcgggcgtca gcttgaattg cgacatgatg ttattcctct
     2461 gaatcctggt tatggctcgt tcggcctgtt cgtgttcgtg ctcgtgtgga tcggcggcga
     2521 tgccgcacgg cgcgccgaca tgcggtgtcg tcgcgccatc tacgccgcgt gcagcggcaa
     2581 ccgttcgctc gtcacgacgc ggtcgccgcg gcctcccgat aaacctgcga ccatccttcg
     2641 acggtgggcg ccgccatcag cttgctcgtc ggcacctggc gctgcagctg ctgctcgatc
     2701 tgaatctgca attcgacgat cgtgagcgag ctcacgccgc gctcgaagaa atcttcgcag
     2761 gaccgaagat cgggaatccc gagcacgctg cggcaggcgt tgtgaatcgt ttcggtgatg
     2821 tctatcgtgt gggtcatggc ttctctccga tggtctaggt ctcgctgacc ggcagcctgt
     2881 tgcgatcgag cttgccgttc gcattgagcg ggatgtgctg aaaaatctgg atatcgtcgg
     2941 gaatctggaa cggcggcacc cgcttggcca gttcgcggcg aacgtgggct ttcatgtccg
     3001 gtccggcgcg gccggattga acgatcgcgc tgaggcgttt ctcgccggtc gcttcttcgg
     3061 ataccttgac gatcgcctcc tcgacgccgg gaatgccagc gatgacggac tgcagctcgt
     3121 cgagcgacac acgatagccg cgtatcttca caagccggtc gccgcggccg aggaactcga
     3181 tcacgccgtc cgcccttcgc cgcgcccggt cgcccgtgcg atagagcagg ccgcctgccg
     3241 ccgggcaatc gacgaacgcg gcgcgcgtcg catcgggcgc gttcaggtag ccgagcgcga
     3301 cgccaaggcc gctcgcgcac agctcgcctt cggcgccgtc cggcacctcg cgcagtgccg
     3361 catcgagaat gtgaacgccg gtgcccgtga tcggccggcc gatcggcacc gtatcggtgg
     3421 gccgccggtc ggccgtcatc acgtggcagc acgtgaatgt cgtgttctcg gtcggcccgt
     3481 atccgttgat gacggtgatc gacggatatg cgtcgaacac cgcgccgatc gcggcggcgt
     3541 tcagcacgtc gccgcccgcc agcacgacgc gcagacccgc cagcatgccg acgaagcgcc
     3601 gcgcgacgag atggaacagc gcggcggtga gccacatcac gctgactttc tcgcgcgcga
     3661 tcagccggct gacggcgttc ggatcgaacg tggcgtcctc gtagatcgca agccgcgcgc
     3721 cattgagaag cgcgccccag atctcgaagg tcgacgcgtc gaacgtgatc ggcgagagca
     3781 gcagcagcgt gtcgtcgcgc gtgatccgga tgtagttcgt ctgccgcacc aggcgcgcga
     3841 cgccgcgatg cgcgacgatc acgcccttcg gccgcccggt gctgccggac gtgaacatca
     3901 cgtaaatcgg cgtttctccg tcgtgccccg catccacttc gggcccctga tcgtcgcgtc
     3961 ccgtcgacag atcgtcgatg tcgagaacgc acagcccgtc atgacgaaac gcctcggcgt
     4021 cggccgcgcg cgcgagcaca tgccgcgcgc cgctgtcgct cgcatagccg cgcttgatcg
     4081 tgtcgggata cgcggggtcg accggcacga acgccgcgcc ggtcttcatg accgcgagca
     4141 tcgcgatcac cgcgtcggcc gagcgcggca cgcagagcag aacccggtcg cgcggccgca
     4201 cgccgctgtc ggccaagcgc cgcgcgaggc ggttcgcgca tcggtcgagc tcgccgtacg
     4261 tgaggcgcgt gtcgccgctc gaaagcgcga gcgcatcggg cgcaagacgg gcttgcgcac
     4321 tgaacagtcg attgacgctg atggaagtca cggattctct cgcgttctgg gaagcgaatg
     4381 gcccggagga aacagcgggc gcgtgtggcg atgccgcgcc gatgtcgcgc ggccttggcc
     4441 gcttacgagt ggcgcagcgg agcgccggcc ggcgaagcgg caggctcgac gccgagtgca
     4501 tcgagcgtga tgtcgtccac ctcgatccag cacgcgaaca ccggcttgcc gtcgatcagc
     4561 cgcggcggtc ccgcacggtg aatatggact ttcaggcgat tgagcagacg ctcgaccgcg
     4621 agcggagaaa cggtgatcag gcgcttgacg ccggcagcct gcgcgaagtg gacgatttgc
     4681 gcgagcagga tgcgcgtatt gcggtgagcc cgctgcagcg catccggccc gccggacagg
     4741 atcgacgacg aaaatcgcga gatttcccac acgtccgcgc agcagggcgg cggcgcatcg
     4801 cccatcaggt cggcgaacac ctcgccgagc aggtagggct tcgtggtggg cagcaggcgc
     4861 gcgcatccgc aaatatcgcc ggactccgtc ttgccgacga cgtagatcgt atcggggcgg
     4921 tcgaattgat cgatttcgag tccgtcgacc aacggcaatg gccagccgag tttctcgatg
     4981 aatatcgccc gacgataatt gccgagtgct gccttgacgg tggaatccag ttgcgcggcg
     5041 cttatgacgg tcgtgtcgat catgtgtgcg taccctcttt agatgcgcac attagagacg
     5101 atgcgacgcc tttgcgaaac tacgattttc tacaggtttt aaattttcaa tcctgaatca
     5161 acggggcgag caatccgcgc caatcgaatt tggcaatcca atccaataga aatcgccggg
     5221 tattttccgg gccgagatca tagccttcgg cgctgataat catcagattc gatgccaggc
     5281 tgtccgggac gatgcgcagc gttttctcga cgtcgacgaa ccacgaccag ccgagcgatg
     5341 tcggcgcggg ccaatgcgcg tcgctccatt cgcaatagcc ggcgcgcagc gcgcagatgc
     5401 cgaggtccca gatttccgag aggatctgat cgtccgcggc cgcgaacgtc ggcgcgagcg
     5461 acacgcgcgc cagttgcggc agcgacagac gaacgtatcc gtcctggccg gcggcggccg
     5521 gtgcggatga agccggagca gagcgttggg ccacgtggat ctccttccga cgcgccgggc
     5581 gcggcccatc gcccgcccgt gccgggggtt aaatgagcgg cgagccgcaa cacatgcgcg
     5641 gctcgccgcg gggcgacggc gccgcggcgg agcgcgaacg tgacggtggc gtgtccatgc
     5701 cgaatgacgg ggaatgaagg gtgagcggaa atcgtgcggt gccgaactgc tcgatgcggc
     5761 gcgccgataa ataatcgaca cagtgcattt ttgttcggcg gattctgcct aatcgatgag
     5821 cgatgcgcaa gccattaatt gcctatgcgc atgcaaatcg ccgagcgtcg cctgcctgat
     5881 gcgagtgaca agcgctttcc gacaagaaag ccgggcaatg cggaattaaa cttgcattcg
     5941 atgagttgtt ttttatcgga aggcagcgtg aattcacgat gaggcgaggc gatattcgca
     6001 tcgcttcatt ggggcgcaac cacgggattt tccgcttccc gcgtaaaagg agtcattcga
     6061 ctatcagatt tgatagttgc tccggtcgag ggtttgcatt gtactgacgc ggctttggcg
     6121 gccgaacgtc ggccggaaca cgaacgctgt cggatcgccc gcaatcacgc cggtcgaacc
     6181 gaggaggatc cggatggtta tgtggttatt gcagctcgcc ttgatcatcg ccgtgtgcgc
     6241 ctgcttcggt tggctcgcac agcgcgtcgg gcaatcgaaa gtggtcggcg aactggctgc
     6301 gggcatcgcg ctcggcccgg cggccctggg cgcgatcgat tcgaacttct acgcaaccgt
     6361 cttcggcccg ggcgcgtcta ccgggatggc gcaactgggc gaggtcggcg tgatcgcgct
     6421 gatgtttcag atcggactgc acatgaacct cggcggggcg tcgacgctgc ggtcgctgag
     6481 aaccatgccg cccgcggtcg tggtcgccgg aatcggcatg ctgctgccga tggcgggcgg
     6541 catcgcgatc ggctatctgt cccacggcgc gctcgcgccg cggatcgccg cgctgcccta
     6601 tgtgctcttt tgcggcgtcg cgctatcggt ttccgcgctg ccggtgatgg cgagaatcgt
     6661 catggacatg gagctcgtcg acgcgccgcc gtcgctgctc gcgttgtcgg ccgcgatgct
     6721 gaccgacctg gcgggctgga tcatgctcgc gttcgtttcg gccatcgcgg ttgccggcgc
     6781 ggatgcgtcg gggccatcgc atatcgtcgc cggcatcgcc gtgttcctgc tgctggcgaa
     6841 gctggtcgcg cggttcgtcg tctcgccgct cgccgccgac gcggcgaagc gggcgtcgcc
     6901 cgcgaagctg atgagcgtcg tcgttcccta cgtgctggtt tgcgcgtggg cgacgacggc
     6961 gatcggcgtg cacagcgcgt tcggcgcgct gctcgccgcc gtgatgctgc gcggcgtgcc
     7021 cgggctgcag gcgcagtggg agcggcagat ggaaggcttc gtgaacgcgg tgctgctgcc
     7081 cgtgttcttc gtctattcgg ggttgcgggt caccttcgac agcttcgacg gcgcgtcgcc
     7141 gtggctgtgg ttcgtgccgt tcctgtgcgt cgcgttcgtc ggcaagttcg gcggtgcgta
     7201 tctcggcgcg cggatctgcg ggatgaaccg gggagatgcg gcgctcgtcg gctcgctgat
     7261 gaacacgcgc gggctcgtcg agctggtcgt gctgtcggcg gggctgcaga tccatgcgct
     7321 atcgcagagc gcctacgcgg tgctgctgct cgtcgcgctg accacgacgg cgatgacgac
     7381 accgttcgtt cgcttgtggc ggcgcgcggt attgcgtccg gcttgatgtc gcgacgatcc
     7441 gctgcggcgg cccatcatcc tgcacggctt tctcacatga acagaagatc gatcatcgcc
     7501 gacgacggac gcgagctgaa cgcattcgtc tacggcgcca atcccgatgc gccggccgtc
     7561 gtggtcgtgc tgccgttcgg cgcccggcac gcgatgctga gcaggttcta cgacgcgctt
     7621 caatcccgct tcaccgtcgt gacgtgggaa tcgcgattcg tgctggatgt cgatcgggac
     7681 gacgacgatg ccggcatcgc cgcgcagacg catgcgcgcg atctggcgag cgtcattcgg
     7741 gcgacgacgg ggcgcggccg gaacgtccct gtcgacgtgg tcgcctactg ctcgggcgcg
     7801 ggcgtcgcgc tgctggccgc gcaccatcat ccggacgcga tctcgcgcat cgtgctcgtg
     7861 agcggtgaat atctgctgcc ggccgccgtc gcggcgccca ccgacatcca gcgccagatg
     7921 gacatcttcc tgtcgctcgc ggcgcgcagc cgtgcgatcg ccggctcgat ccaggagaag
     7981 atcgcggcgg cgcaggagcg ggggcagacc gaattccaag cgcatctgtc cgagccgttt
     8041 tcatcggacc tgcacctcca tcgatacggg atcaactacc tgtcgtatcg cgacgtcgac
     8101 atgatcgaag tggcgaagca ggtctcgcat ccggtgctgt cgatcgtttc gacggaggac
     8161 atgcacgtcg gtccggccgg atcgctcgag atatcccgcc tattgcgtcg ttgcgtgcgc
     8221 aacgtttccg tggcgggtga ccattatgaa atctgccggg gcaacgccga catcgtcaaa
     8281 agcgtcgtcg agtttttgga cgccgacgaa ccgacgcttc gcgagacgcc ctgatgcgga
     8341 ttcgccatgc tccggccgaa tgagcgcgcg tgtccgcccg gtccgtcgtt cgcgaggcac
     8401 gggacgcgct cgaggctgcc acgcccgatc cgtcacagca tgcccatcag cgccgccttg
     8461 gccaccgcct gtatcttgtt cgtggagccc agcttggaga cgatgttctt cacgtgaaaa
     8521 ttgacggtgc tttccgagat gctgagaatc agcgcgattt cgtacgccgt cttgccgtcg
     8581 gccgtccact tcaacacatc ggtttcccgg cgcgtgaggt ccggatcgaa ttcgtcggcg
     8641 gcgggcagga acggcgccat cgacgcatgg gcgacgttgg cgagccaatg gacgatgctc
     8701 tcgttgcgga atttctcggc cgtgtcgatc gcgtcctgcc ttctcgacaa cgacagcacg
     8761 ccgatcgtgc cgtccgcgcc cctcgacgcg gacgaccagc cgtgagcgat gccgaacgac
     8821 agcgcctcgg cccagaacgc gctcttcgac gcgttggtcg atgcggacca ggtcaccggc
     8881 cggtcgctgc cgagcgcggc cttgaccgcg ctgtcgacgt tggcgaatcg cgcttcgatg
     8941 tagcgctcct gccaccggtc gggatagttc gacaccatga ggatctgcgg attgctgatc
     9001 ggaaaagggc ggcgcatgcc gtaggcggcg tattcgtagc ccagggtggc ggccgcgcgg
     9061 gtcaagacgg aattgacgtg ctgtgggttc tcactgcggg aaaattcgtt tagccaaaat
     9121 tgaagaaaat cgtgcatctc catatcctcg cattgaaata ccgagaaaca acagtattcg
     9181 ggcggcgacc tcgatgaagg ttcgcagtcc ggtgtcggtt attttttggt tcactctggc
     9241 ggtgaaatga tgtcaggtaa agacgggatc tcgtcccgac tgcgaagata ttgccacaac
     9301 aattacagtt ttgagtactc ccgtgcattt atcgagcgcc gcataatttt ccaaattaat
     9361 cattggaatt tccggtgaca tccggatttg aagcccgcgt cggcgaattt tggggatgaa
     9421 cattttacta gtccgatttg gcgaaaaatt gacgcaactt gcaacaatgc cgtgtatttt
     9481 tttgtgagcg tcggcgcgtg atcgccgctt cgccacgggc attcgaaccg gccgtggcga
     9541 tgcgcccgac acgtctgacc gagtgatcgg aggctgatgg agaacgcgga cgagtccggt
     9601 gcaagcggcc gtcccgggct ttcacgagtg ccgggccgcc cgtcgccggg gccgtcgaaa
     9661 cggccgaaac ggctggcctg cggcggctag cggtctatcc ggcagtgccg cagcagcgcg
     9721 tccaggctcg gcgcgcggcc acggaacgcg atgaacgatt caagcgcggg ccggctgccg
     9781 cccggctcga gcacttcggt ccgatagcgc tcgccggctt cccgctttcc cacttccgca
     9841 cgctcgacgc tcgcttcctc gacggcggcg tacgcgtcgg ccgcgagcac ctgcgcccat
     9901 tgatagctgt aataggccgc ggcatagccg ccggagaaaa tgtgactaaa tgtattcgcg
     9961 cttcgcgcct ggcggtctag cggcgtcaat tcatatttct gataaatttc atgtatcgtg
    10021 ttttgcatcg aattgattga atctatttct tggcgcgaat gcaacgcgat atccagcatc
    10081 gacaacgcga tctggtgagc catttcaatg ccctggttga aatggcgggc ggccagcatg
    10141 cgctcgaaca gcgtattcgg taatggctcg cctgtttcga cgtgagcgct cagcgtggaa
    10201 acgacatgcg ggtcccagca aaaattctcc atgaattgcg acgggaattc gattgcatcc
    10261 cactcgacgc cgttcgtgcc cgatatcgcg ctttcggcca cgccggtcag catatggtgg
    10321 aggcagtggc ccatttcgtg gaacagcgtc acgacctgat cgaaggcgaa gcaggcgggc
    10381 gaaccggcgg cgggcgcggc cacgttgcac atcagatagg cgacgggcgt gcgtatggag
    10441 ccgtccgggc ccgtggcgcg cgaacggccg ctcgccgccc aggcgccttc ccgtttcccg
    10501 tcgcgcgcgt acagatcgag gtaaaggtgc gcgacggttt cgccgcgcag gtcctccagc
    10561 cgaaacaggc gaacgtcgtc gtgccagacg ctgccttcgt cggggcgaat ccggatgtcg
    10621 aacagcgttt cgacgaggtc gaatagcccc cgcaacacgg cgtgctcggg gaagtagcgg
    10681 cggacgtcct ccgtcgagac cccgaagcac tgctggcgca tgcgctcggt ggcgaacgcg
    10741 atgtcccacg gctgcacgtc ggccaggccc agttcgccgc gcgcgaacga ttgcagcgcc
    10801 tgccactcga ggctcgcctt cggactcact cgccgatgaa gattctcgag aaacgcgcat
    10861 gcgcgctcag gggtgcgcgc catcttccgt tcgagcgaca tctgcgcgaa atcgcgatag
    10921 ccgagcagcc cggcttcctc gtgccgcagc ttcagcattt ccgccatgac gggcgcgttg
    10981 tcccattgcg cggcgccgtt cgcgtatgtc gcgccgagct ccgacgcccg cgtcgagcgc
    11041 gcccgataca tttcctcgcg caacgcccgg catgtcgaga actgcatgac ctgctgatag
    11101 gacgcgaaat ccagcgtgaa ttcgaagcct tcggccgcgc gtcgcgccgc cgcggcccgg
    11161 gcagccgcgc gcgcgtagtc gggaatgccg tcgagctcgg cgtcatccgt cacgatgcgc
    11221 gcaaatgcgc gggtggcgtc ggcgatgttg tcctggtacg cggtggcgag ctgcgcgatg
    11281 cgctcgcgca ggacattcag gcgcgctctc gggcccggcg gcagctcgct gcccgcgagc
    11341 cgcgcgtcgc gaatcaggtt ccgcacgacc gtgcgccgtt cgggcgcgag ggcgcaaaag
    11401 ccgtccgatt cggcgacggc gcgatagcga tcgagcagcg cggcgttttg ccggaagcgc
    11461 gacagggccg ccgacacccg tcccgcgcac gaaccgtatg cggctcgcaa gggcgccgaa
    11521 tcgcataccg acacgagatg cgtgacggtg ccccacgcat attcgagcga ttcgagcgcg
    11581 agactgatcg gctcaatcac attgacccaa ttcggcgggg aatttttcgc gctcgcacgc
    11641 aatatcgcgt tatcgagatc aatcagaagc gcatcgacgg cctgacttac atggaaatcg
    11701 cgaattgatt caaaacgggg taattgagat cgatccagaa ggggattgac taatgttgtc
    11761 ggcgccacga atccgctcct ctttcaatgt cactgaacga tagcgatgat tgtatgaaga
    11821 cgcaaggagt gcgatacgtt gcgttaccta ttagttcttg cagttactga tgcgaagggg
    11881 ccaagttatg cttttcgcga aataattcaa cgaattcaat agacggaatt cgatttcgtc
    11941 acgcaaattt caggaatgcc gcatgctcca agctgtcaat gaaacattgc cgctcacgaa
    12001 cagccagatg gcaatgtggt tgcaatggaa atacgcgcct gacgatcccg cctataacaa
    12061 tccgctgctt ttcgaactcg acggagaggt cgacgtcgag cggttgaagg aggcattcgc
    12121 cgcggtggcc gatgcgcacc cggccattcg gatgcgcttt atcgagcgtg cgggcgtgcc
    12181 ggttcagtac agcgaatcga atccgcgcgg accgctcgaa ttcgtcgatc tgtcggacgt
    12241 cgatccttcg gtgcgccagc aacggatcga cgccgccgtt cagggctgcc ttctcgcgcc
    12301 gttcgatctg ctcgccgagc ccgtccaccg gttcctgctg atcaggacgc ggccgcgcgg
    12361 ctatctgctg gcgctgaaca tccaccatgt ctgcgtggac ggcgcatcgg cgctgatctt
    12421 gctggacgac atctcgtccg catacggcga tcgcgccgct tatgcggctg catcggccgc
    12481 acgcacgggc cagggattcg acgcggtgtt gaacctcgag cggcagcgct gggcggacgg
    12541 cgtccacgcg cagaccgaag cggcgtggcg cgcgcatctc gccgatcgcg tatgcagcgt
    12601 cgagttcgcg aagctcgcgt tcgacggcga tcgcccggcg ggcgacggcg cgaggcaata
    12661 tcgatggacg ctgcccgaca cgctgccggc caggctcaag gccgtcaacc gcgtgacgcg
    12721 aacgacaccg ttcgtcatcc tgatgagtgc gttcagcgtg ctgctgcatc gctatttgca
    12781 gcaggatgcg ctcgcgatcg cctatccggt cgatacgagg ccgtccggct tcgcgcggat
    12841 cttcggctcg ttcatcaatt tcgtgccggc gttcgtcgac gtgtcgcccg acatgactgc
    12901 cgacgcgctg ttcgagaagg tgcgccagca gcggcgtcag accaaggcga tcgcggactt
    12961 cccgcaggtg gatttgatgc ggctcgcgcg gcgaacgctg gccgattcgt cgtcgccgtg
    13021 cctgaacgtg gcgctcgtgc ccgcgcgctt cgcgctcgat tcgctgaagc tgggcggcgt
    13081 ccgcgtcgag caaaggcact atttcgtcgg ctcggcgaaa caggatttgg cgctgctcta
    13141 cgacggcgac gatacgctga gcctgatcct cgaataccgg cacggcttgc tgagcgaatc
    13201 ggtcgcgcgt cagatggcga gcgacttcaa cgtcatcgtc gagcagatcg tcgatcggcc
    13261 ggacctgcgg atcggcgatc tggcgttgtc cgatcagcac gcgttcgccg aacgccatgc
    13321 gacccttgcc gacgccgcgc cacaaactac ggccgtcgcg gcgatcgaac gcgcgctgcg
    13381 tgagcagccg acccgcatcg tcgccggcga gccgggccac gcggtgtccg cccggcagtt
    13441 gagcggcgcg tcgaacggga tcgcgcgccg actcgcggcg gcgaacgtga aggcgggcga
    13501 tcgcgtcggc gtgcggatga accgcggcgg cgcgctgctg gcggcgctgc tcggcatatg
    13561 gaagatcggc gcggcctacg tgccgctgcc gacggatctg ccgcccgcgc gccgcgcgca
    13621 catcgcggac gacgccgggc ttgcagcgtg cctccaccgg accgctccgg ccgatccgac
    13681 atcgcacgac atcgtgctga ccgacgagat tttcgccgcg cccgacgccg aggcgctcgc
    13741 cgacatcgat gccgatccgg acggcatcgc gtacttgatt tacacgtcgg gctccaccgg
    13801 cgtcccgaaa ggcgtcgagg tgacgcatcg caacgtcgcg agcttcctgc gcgcgatggc
    13861 gggcgcgctg ccgatcggcc gcgacgatcg cctgctcgcg acgacgacga tcggcttcga
    13921 catctcgctg ctcgaactgc tgcttccgct gaccgtcggc gcggcggtca tcgcatgccc
    13981 ggagcacgtc cgcatcgatg cgaaggcgct cgaacgcgtg atcgacgacg agcggatcac
    14041 gtggctgcag ggcacgccgt cgttcttcaa cgtgctgcgc gcgggcggct ggcgcggcaa
    14101 caagggcttg aacatcctgt gcggcggcga gccgatcgat gcgtcgacct acgactttct
    14161 gcgcgacgcg tgcgcttcgg tctggcaagt ctacggcccg accgaagcga cgatctggtc
    14221 gacgatcgcc ggccccgagg ccgatggcgt agccggcctc ggcgaaccgc ttcgcaatac
    14281 gacgatccat ttgctggacg cgcacggcca gctcgtgccg cgcttcagca agggggaaat
    14341 ctgcatcggc ggacacggcg tcgcgcgcgg ctaccgcaat cgcgccgcat tgaccgccga
    14401 gcgcttcgtg cacgtgcccg gcgccggccg cgtctatcgg acgggcgact tcgcgttccg
    14461 cgattcgcat gagcggctgc gctttctcgg ccgcgaagac gggcaggtca agatccgcgg
    14521 ctttcgggtg gagctcggcg aaatcgaaaa gcagatcgaa gcgctcggag aggttcgaaa
    14581 ggccgtcgtt ctggtgcagc gggcaacggc cgccgagccg acgttgatcg catggtgcga
    14641 gccccgcgcg ggccgcgcgc tggagcccga cgcgctgcgg gccgcgcttg ccgctgcgtt
    14701 gcccgcatac atggtgcccg cgcgaatcgc gcggatcgat tcgtggccgc tcaacgcgaa
    14761 cggcaagatc gatcgcggcg cgctggccga tcgcgcgacg gcgcccacgt gcccgccgca
    14821 agcgccgccg ctcgatgcgc tcgatgcgct cgttccgact tttcaggcga tttacgcgga
    14881 cgtgcttcgt ctggacgccg tcgatcctcg cgcgacgctg atgacgctcg gcggccattc
    14941 gctgtccgcc gtgcggatca tcgcgcagct ccggcaaaag ctgaatgtcg acgtcggcct
    15001 ggagacgttc atggcgaatt cgagcatcgt tggattgatc ggcagcctgc gtgagtccgg
    15061 cgcgttgggc gcggcagata acggcggcgg agacggcggg cgggcgtcgc cgcccgaggc
    15121 ggaaggcgcg gcggcgacga gcgaaaccgt ggtcccgagc gcagcgcggc cggacgcgag
    15181 cgccgcgtcc gcgccgtgcg tatcggcgcg gacgctgaag ccgtcggcga gcgaaaaggc
    15241 gctttacttc ctcgacagcg tttcgacggt gcggcagacg tacaacatcc cggtggggct
    15301 gcattttccg gaaggcgtga acgccgacgc gctggagcgc gcgctgaggc acgtgctcga
    15361 cacgcacgaa tcgctgcggg ccgcgttcga gcccaccgcc gaggggctgg tcaagcgcat
    15421 ccatccgacg cccgccggcg cgctgatcga gcgccacgcg ccgaccgatt tcacgacgct
    15481 tcgccggacg ttgaaccgga tgctgcgcga gccgttcgag ctgcacgaag ggccgctgat
    15541 gcgcgcgcat cactttccgc tggaggaggg cggcgcggcg gtgttctatc tgtttcacca
    15601 catcgtcgtc gacggaatcg gctgcgggaa tttcctgcgg gagatggcgg gcgcgtacga
    15661 ggcgatccgc ggcggcgcgc agccggtggg cgacggcgct tccacgggcg acgacgatga
    15721 tccgccggcg aacgccgccg cgcgcgtcga cgagctcatc agccgattcg gcatcgtcga
    15781 tcgcgtgctg aatctgccgt atcgcgcgcc gttccccgag gtgcgcacgc tggcgggcga
    15841 cagcctcgcg ctcgagatcg ccgccgacgt gcgcgccgaa ctcgacgaat actcgcgcgc
    15901 cgcgggcgtg ccgctcgcga cgatattcct gagcgcgttc gcgctgacgc tgcatcgcct
    15961 gagcggcgac cggatcgtca atgtcggcct ggcgacgatg aaccgcacgc cccggacgct
    16021 cggaaagatc ggcctgtaca cgaacacgat cgtgctgccg gtcgaaatcg agccgtcgag
    16081 ccggctgagc gacttcgtcg atcgggtgac ggcttcgctg ttctcgatct acggctatgc
    16141 cgacgtgccg ttcgaggagg tcgcgagccg cctcgtcgag tacgcgtcgc tcggcaggac
    16201 ccctgtcttt cagacctttt tcaatttcat cgatcgctcg atgtacgagt tctcgatggc
    16261 ggggctgccg gtgcgggaaa tcgcgctgcg cccgaccggc gcgaagttcg agctgtcgct
    16321 cgaagtcaac gacttccgca cgcacacgca agtcttcttc gaatacagcc aggacgtatt
    16381 cgacgaagcg ctcgtcgacg agatcgcgtc cgagttcgtc cgcagcctgc tcgcgtgcgt
    16441 gcgctccccc ggcgacgcgg tcgagcgact tgccctgacc acgcaatctt gaggaaaaca
    16501 tggaacaggt agcactgatt ggatcccgac tgcggctgcc cggcgccgat acggtcgatg
    16561 cgttctggga gaacatcctt gccggccggg attgcatcga ttcgctgtcc gacgcggagc
    16621 tgctcgcggc gggcgtcgat cccgcggcgt tgagccagcc cgagtacgtg aagcgggccg
    16681 gcgtgctcgc cgacgtcgac cgcttcgatt accgcttctt cggttacacg ttccgggaag
    16741 cgcaggcgat cgacccgcag cagcgcgtgc tgctcacgct cgcgcatcag ctgctcgagc
    16801 aggtcggcgc gtcgagccgc gacgtcggcg tctacacgtc gatcggattt ccgcactacc
    16861 tgctgaacaa tctgagcgcc caggcgcccg gccgggtcgc gttgtccgac gtggtgttcg
    16921 gcaatagcgg cgattgcgcg tcgacccgca tcgcatacaa gctggatctg cacggcccgg
    16981 cgatgtcgat ccagtcggga tgctcgtcgg cgctgatggc gctgcacagc gcgcggatcg
    17041 cgattctcac cgggcagtgc cggatggcgc tcgtcggcgc cgccgcgatc cgcacgccgc
    17101 aaaaggaagg gtatctgtat caacgcgacg gcgtgctcgc gaaggacggc gtatgccggc
    17161 cgttcgacgc gcgcgcgtcc ggcaccgtgt tcacgaacgg cgcggtggtg ctcgcgctga
    17221 aggcgttgtc cgccgcgcag cgcgacggcg acgacatcat cggcgtgatc cgcggctcgg
    17281 cgatcaacaa cgacggccag cgcaagtccg gctacacggc gccgagcgtc gccgggcaaa
    17341 gcgaggcgat tcggcgcgca tacgagcgca gcgggattgc gccggagacg atcggctacg
    17401 tcgagacgca cggcacgggc accgcgctcg gcgacccgat cgaaatccag gcgctgaagg
    17461 acgcgtatgg cgggcatggc ggcgcgagcg cgcgttgcgc gctcggctcg acgaaggcga
    17521 acatcgggca tacggacgtc gcggcggggc tggcgggcgt gctgaaagcg gcgctgtgcc
    17581 tgaagcacgc gatcaagcct gcgctcgccg gattcgagcg cgcgaacccg aatcttccgc
    17641 tcgacggctc gccgttctac attccgagcg cgcccgaacc gtggccggac gcacccgggc
    17701 agccgcggcg cgcggcggtc agcgcgctcg gcgtcggcgg cagcaacgcg cacgtgatcc
    17761 tcgagcaggc gccgggccgc gatctgtcgc gccgcgtcga cgcgggaccg ctgctgatat
    17821 ccgcgcaaac gccgcccgcg ctcgacgcgc tcgatgctcg atatgacgag gcgctcgcgc
    17881 ggcaaacgct gccgtcgggc gatgcgcgct acacgtcgca actgttccgt cagcattatc
    17941 cggagaagcg ggcgttcgta ttcgagccgt cgggcggccg gcgccgggtc acgccgtcgg
    18001 gcgactggcg tcacgcgcaa gcggcgctgc tgtttccggg ccagggcacg cagtacgccg
    18061 gcatgggcgg ggcgctctac gcgcgcggcg ggtggttccg cgcggcgttc gacgattgcg
    18121 ccgatcgctt cgtgcgcgaa ggctgcgcgg acccgcgcga gctgctgaac gcggacgagg
    18181 cccgcattcg cgatacggcg gttctgcagc cttatctgtt cgcgctcgaa tatgcgttgg
    18241 gcgcgacgct gctggcgatg cgcttgccgg tcgcggccgc gatcgggcac agcctcggcg
    18301 aatacgtcgc cgcgacgctc gccggcgtgt tcgatctggc cgacgcggtc gcgatcgtcg
    18361 cgatccgctc gcgcatcatg agccgcgcgc cgcgcggcgc gatgctcgcg gtgctcgccg
    18421 acgaggcgcg agtcacggcg ttcctgaacg acgagctgtc gctgtgcgcg gtcaacagcg
    18481 atacgtcgtg cgtcgtgggc ggcaccgagc aggcagtcga cgcgctcgcc gcgcgcgtcg
    18541 cgcaagcgca gctcgcgtcg gtgaggctgc cgacgtcgca cgcgttccat tcgcacctga
    18601 tggaagcgag cagccgcgag ttcgcggccg cgttcgacgg cgtgtcgatg cgcgcgccgc
    18661 gctttccgat cgtctccaat ctcgacgggc gcgcggattt gcccgagcgc ttcgcgaccg
    18721 ccggctattg ggtcgaccat ctgcgccgtc cggtccgctt ccgcgattgc ctcgcgacgc
    18781 tggcgtcgct cgtgccgttc ggcgcgtgga tcgaggcggg gcccggccgg tcgatcgcca
    18841 atacgtttgc gcggctgccg ttgaccgacg cgagctgctt cccgacgatg ctgcccggac
    18901 acgaaacggt gctgttcgac acgctggccg cgcaatgctg ggccaacggc gtcgacgtcg
    18961 actggacgcc gctctacggc gacgcgcgcg gcaacgtggt tccgctcgtg ccgcatccgc
    19021 tcgacgagat ctcgtgctgg atcgacgcgc cggcgaagcg gtccgcctcc gacgcggcgc
    19081 ccgaatacca gaagcagagc gatatcgatc agtggttcta cgaatacgac tggaccacgg
    19141 tgccgccgcg cggcgacggc gcgaagccgg acgaggcggc ggagacggcg atcgccgatt
    19201 cggtcctgct gatcggggac gcgagcgccg aagccgcgct gctcgccgag cgcgtcgcgc
    19261 gggacgccgc atcgttcttc gtcgtggacg gcgcgcatcc ggacgtgctg gacggacggc
    19321 tcgcggcgat cgcggcccag gccggatcga aacagacgcg catctcgcgc gtgttgatcg
    19381 tcgtgccgtc gcggcgcgac ggcgcggccg cgcatcgcgc ggattcggac gacacagaaa
    19441 cgcacgacga atcgggccgc gcaatcgatg cgatgctgtc gatgcaacgt acgttcgatg
    19501 cgctgcgcaa cgcattgccg ggcaagctcg acatcgcgtt gatcgcgttt tccggcgtgc
    19561 acgcagacga ggcccggccg tcggtcggac gcgcgtggat cgacagcttc gcgaccgtcg
    19621 tgcagcagga attctcgcgg atgatctgcc gcaccgttca cgtggatgcc gcggccctcg
    19681 cgggcggcga gacggacccc gaagcaagcc ggcgctcgat cgatgcgctc gcgcgcgctt
    19741 gcctgcgtca ctcgggccgg ttcctgcgca ttcgcgacgg ccggttgatc gagcgcaagc
    19801 tcaagcgtgg cggatcaagc gccgcgcccg cgccggccgc ggcgccgaaa tcgcctcgca
    19861 gcgtgctggt cgtcggcgga gcaggaaatg tcgggatgat ctacgcggcg ttcttctcga
    19921 ccgtcgtcgg cgcggacgtc gcgatcgtca gccgcagcgc gagcgcgttc tcgaacgcgc
    19981 tgcgcgatcc gagcgccgcg gcggaccgcg cgctgcggcg gcgcaaggcg ctgtacgagc
    20041 gcatggtcgc ggccgggcgc cggatcctgt tcgtcgatgc cgacgcgacc gatccgctgc
    20101 aactcgaacg cgccgcgcaa tcggtcgccg acgcgttcgg ctcgctcgat ctcgtcgttc
    20161 atgcggcggg cgcgccggcc gacatgcact accggacgtt cgacgatacc gatgtcgcgt
    20221 atctggatgc gctcgtgtcg ccgaaactcg acgtatgcgc gaacctgcat gcgctgaccc
    20281 gcgcgctgcg cattccgcgc gtgatgatcg tgtcgtccat ttcggccacg ctcggcggga
    20341 tcgggctgta cggctacgcg gcgtcccact cgctgctgaa cgcgtatgcg cagtcggcga
    20401 gcagtgcggc gtgccggtgg accgtgatcg actgggatgc gtgggaattc ttcaaggaca
    20461 cgcgcgacga ggcgaatgac gacgtcggca tcgatcacta cgcgatcagc gaacaggaag
    20521 ggctgtcggt gctcgagcgc ctccacgcgc tcgattggcc cgcgcacgtc gtcgtcgcga
    20581 gcggcgatct gatcgggcgc tatcgcaact gggtgctgtc cgagcgcgac gaaacgcccg
    20641 ccgcgcagca gatcgtcgcg ccgcgcccgc tgctgaagga cgagctgatc gcgccgcgca
    20701 cccgcaccga ggcggcgctc gcgaagctgt ggggcgagtg catcggcgtc gagcccgtcg
    20761 gcatacgcga caacttcttc gagctgggcg gccattcgct gatcgcgctg aaactcgtcg
    20821 accggatcaa tcagacgctc gactgggatc tgtcggcggt cgacatgttc aagtttccga
    20881 ccatcgaacg tctcgccgac gcgaacgcgg ccgacgacgc cgttgccccc gatgcggcgg
    20941 acggcgcgcg cgacgatgcg cacgacgacg ccgtgccggc gtcggctgcg ctcgatgcgg
    21001 gcgtgcacgc gcagcggcgt cgccatcact actaccaaag cagaaaacac agcatggagt
    21061 cgaaaagtga ataatcttga cgtcgcgatc atcggcatga gcggagcgtt tccgggcgcg
    21121 tccgatgtcc gggaattctg gcgcaatctg gaatccggcc gttgttcact ggagcgctat
    21181 tcggagcagg aactgctcga cgccggcgtc gatcccgcgc atctgaagtc gccgaagtac
    21241 gtgccggtcg gcggccgcat gcgcgacatc gaatgcttcg acaacgaatt cttcggcatc
    21301 agcaatcacg acgcgcggct gatggacccg cagcagcgcg tgttcctgca gctcgcgtgg
    21361 catgcgttcg aagacgcggg cttcgtgccg ggcgcgcatc cggggcgcgt cggcgtctat
    21421 gcgggcgtga gcctgaacag ctatctgcac accgtcgtgt tccggtccga cgaagtcgac
    21481 ctcgaccgcg acggccagag catcctgttc ggcaacctga gcgactatct gacgacccgg
    21541 ctgtcctatc tgctcgacct caaggggccg agcgtcaaca tccagaccgc gtgctcgacg
    21601 tcgctcgtcg cgattcacga ggcatgccag ggcctgctga gctaccaggc ggacgtcgcg
    21661 ctggcgggcg cgtgctcgat caacgttccg aacacgcgag gctacctcta cagccaggac
    21721 agtttcttct cgccggacgg ccaggtccgt gcattcgacg agcaggcggc aggcacggtg
    21781 ttcagcaacg gcgcggggct cgtcgtgttg aagcgtctcg aggacgcgct gcgcgacaac
    21841 gatcagatct acgcggtgct gaaggcgagc gccgtcaaca acgacggctc cgacaaggtc
    21901 ggctacgcgg cgccgagcgt gtccgggcag agcgccgtga tccgcgatgc gctgcacgcg
    21961 tgcgagatcc gccccgagca gatccagtat gtcgagacgc acggcacggg cacctcgctc
    22021 ggcgatccga tcgagatcgc cgcgctcacg caggcatacg cggcagaccg gcggcgcggc
    22081 gcggcccacc ggccggcgaa atgcgcgatc ggctcggtga agacgaacat cgggcatatc
    22141 gacgtggcgg caggcgtcgc cggcgtgatc aagaccgcgc tcgcgctgcg gcacaagacc
    22201 ttgcccgcgt cgctcggctt cgagaaggcg aacccgcggc tcggcctcga aaacggcccg
    22261 ttctacgtca atgaccgcac gcagccgtgg gcgtccgaca cgctgcgcgt cgcggccgtg
    22321 agcagcttcg gcatcggcgg cacgaacgcg catgcgatcc tcgaggaagc gcccgtgcaa
    22381 gacccgctgc cggcgacgaa gcccgcgtac tgcctgacgc tgtcggcgcg caccgcgcag
    22441 tcgctggagg cgctgcgcgg cagctatctg gcctttctga gcggcgacga tctgccgtcg
    22501 ttcgcggatc tctgcttcac gtccaatgtc gggcgcaagc cgtttgcaca ccggatcgcg
    22561 atcgcggcga gcggggcggc ggacgccgcg cggcggctcg cggacgcgac ggcggcgacg
    22621 agcgacggac agccgcatcg catcgtggtg tccacgccgg cggccgacgc gaacgcgacg
    22681 tggcaggcga tctgcggcgg cgacatcgac ccgcgcgagc cgctgttcga ggcggccgac
    22741 cgttacagcg cggcggaact ggtggcggcg tatgcggccc tgctcgtcgc gcaactgcgg
    22801 cggctcgggc tcgccgccgc gctgcggcag ccggcgcatc tgccggacag cctcgtcgag
    22861 ctgctcgcgc cgcggcgcga cgatccgctg cgcgagctga tcgcgcaagc gcccgccgac
    22921 gcgtcgcagt cggactatcc gctgacgctg tccgccgagt ccgaactgcg gatcggcacg
    22981 cgcgtgcatg cgctcggcgc gccgtcgctg cgcgggcgct tcgtcgcgga actgctcgcg
    23041 gccggctggg cggccggcgt gccggtggat tgggcgtcgt tccatgcgga cgaggcgcgg
    23101 cgcaagacgt cgctgccggc gtacgcgttc gcgaaaaagg cgctgtggct ttcgaccgcg
    23161 accgaggccg agcggcgcaa tcgcaagatc gaagacatcg gccagtggtt ctacaagccg
    23221 acgtggcgcg aaaccgccgc gctcgccgcg cgcacccggc gcgcggacga accggcggac
    23281 gcgagcgtgc tcgtcttcag cgccgatcgc gcccatcgat tggccgcgcc gtgggcggcc
    23341 gccgcgcgat gcctgtatgt ggtgccgggc gccggcttcg gcgagttgag cgacgacacc
    23401 tattgcatcg atccggcatc cgaaggcgat taccagcgcc tgatcgagac gctggccgcg
    23461 cgcggacgcc tgccgcgccg cgtcgtgcac gcgtggctcg ccgccgaggc cgcgtgggac
    23521 ggcacgccgg cgaacttcgc gaactgccag acgctcgggc tgttcagcct gattttcttc
    23581 gcacgatcgc tgaaccgcgt gacggttggc agcgccgcat gctcgatcgt cgtcgccgcg
    23641 tcgcagatgg ccgcgctgac gcctcgcgag gaggtgaatc cggacaaggc gaccgtgctc
    23701 ggcatcagcc ggacgctgca gaaggagtat ccgttcatcg attgccggat cgtcgatatc
    23761 gcgtcgcacg aactgttcgg cgcgaccgat tcggctgcgc agctcggcct cgagtttctc
    23821 gagccgctca cgcccgaaaa cgaaatcgtc gtgctgcgcg gcgcacgccg ctggcagacc
    23881 acgtatcagc ggttcgccgt gccggcgaag tgcgagccgg acgtccaggc gcgcggcgtc
    23941 tacgtgatat tcggcggtct cggcgagctc gggctgaacg tcgcggccca tctcgcgagc
    24001 cgcgcgccgt gcacgctgct gctcgtcaac tcgaagcgct tcgtcgcgcg cgacgagtgg
    24061 cccgcgtgga tcgacgagca tggcgccgat cacccgtact cgaagaagat cgagaagata
    24121 cgcgagatgg agaaggcggg cgcgacggtg ctcttgcagc aatgcgacgt cgccgacgcg
    24181 aaacgcgtcg acgcggtgct cgacgacgcg cgcgagcggc atggcgtgat ccacagcgtg
    24241 atccacgcgg ccggccgcgt cgagaacggc atgatcgaca acaaggacgt ccgccacttc
    24301 gagacggtgt tcgaggcgaa ggtgtacggc acctacaacc tgctgtcgta cctgaagcgc
    24361 catccggtga cgaaggtgat cctctgctcg agcatgaact cgatcatcgg cgggctcggg
    24421 cagatcgaca acgcggcggc caacgcgttc gtcgacgcgg tcgcgcaaac ctcgctcgcg
    24481 gcgtcgctcg gcgacatctg ctcgaccaac tggggcgcgg tcaacgcgga gcggctcacg
    24541 cgcccgaacg tgctgccgca gttcgcggac ctgagccgcg agcacatgcg caatcacatg
    24601 accgagcgcg agatcgcggc ggtctatgac cggatactgc actggaactt cgggccgcgc
    24661 ctcgtcattt cgacgatcga tttcgattcc gtgctcgagc actggggcga agtgagcaag
    24721 gtgaccgagc tggcgcggct gcgccatgtc gcggcggaag cgggcgagca ggcgagtgcg
    24781 cgcgcgccgg acgacgacgg ctacgcgtat cggtcggagc tgcaccgttt cgtcgaaacg
    24841 agctgggcgc ggattctcgg cgtcgcgcat gtcgactggg acggcgtgct gctcgagctg
    24901 ggcgcgcatt cgctgagcgc cgtccagttc gtgtcgatgg tcaaggaccg ctacgacgtc
    24961 agcctgcacg cgatgatcat ctacgaaatc cggacgttgg gactgctggt cgagcacatc
    25021 gaaacgaagc tgctcgagaa ggccgctcag cttgaagtca gccaataaca ccatgaacac
    25081 gactttcgaa tttgatggag cccagccatg acccactctg ttttcgcacg gttcgagcaa
    25141 gtgtgccgca gcagtccgca agcggtcgcg ttggagagcg gcgagcgccg tctcacgtac
    25201 gcgcagttgc atgacatggt cgcgtcgatc ggcgcgcgtc tcgccgcggc gggcgtgacg
    25261 cccggcgcgc tgctcggcat cttcctgccg cgcgacgtgc ggctgccggc cgcgcttctg
    25321 gcgtcgctcg gcagcggcgc cgtgtacgtg ccgctcaccg agaaatatcc gcccgagcgc
    25381 ctgcgcgaga tcatcgagac gcacggcatc gagcacgtcg tcacgaccga tgcgctcgcg
    25441 tcgcaattgc ccgcgtcgtg cggcaagatc gtgctgcccg ccgaaggctt cgagaaggcc
    25501 gactggctgc ccgccgccgt gcgcccgcag aacgcgcccg tctacgtcgt gttcacgtcc
    25561 ggctcgacgg gcacgcccaa gggcgtgctg atcggcgagc gcaatctcgg caatctgatc
    25621 gactggtatc gcgcggcctt cagcgccgag cagcggcgct cggtgctcgc gtcgacgcag
    25681 atcacgttcg acctgtcggt gttcgagctg atctgcacgc tttgcacggg cagcaaggtc
    25741 gtgatcgtcg agaacgtgct gcaactgctc gacgacggcg cgccgtgcga cgtgagcctg
    25801 atcaacacgg tgccgtcggc ggcgcgggag ctggtgcgtc accgcaagtt cccggcggcg
    25861 gcgcgcgtcg tgaatctggc gggcgaggcg ctgtatcagg atctcgtcga cgatatctac
    25921 gaaacggcgc cgcaggtcga gcaggtgttc aacctgtacg gcccgtccga ggacaccacg
    25981 tattcgacgg gccacgcggt gccgcgccgc gccgcgagcc gcacggtcag catcggccgc
    26041 tcgctgccgg gcaagcacgc gcacatcctg gcggacgatc tgacgcccgt cgcgcccggc
    26101 gaggtcggcg agatctgcct gagcggcgaa ggcgtcgcgc tcggctatct gaacgacgcg
    26161 aagctgacgg ccgaaaaatt tccgacgatc gggcacggcc cgctcgccgg gcagcgcatc
    26221 taccgcacgg gcgacctcgg cagcttcgac ggcgacggcc tgctgcgcta tctcgggcgc
    26281 gcggaccgcc aggtgaaggt gcgcggcgtg cggatcgagc cgggcgagat cgaggtcgcg
    26341 ctgcgcagca tcgaaggcat tgcggatgcg gcggtggtga aggtcgtcga tgcggcgaac
    26401 aacgatcagt tggtcgcgct cgtcgtcgcg cagccgtcag ccccgagcgc gaacgacgtg
    26461 ctggaccggc tgcaaacgct gatcccggcg tacatggtgc cgtcgcgcgt cgagctgatc
    26521 gacgcgattc cgctgaacgg caacggcaag accgatcgca cgaagctcga gcagatcgcc
    26581 ggcgcgctgt tcggcgctgc gccgagcgcc gacgacattc aaccgcgcgt cgcggagatc
    26641 gtggcgaagc tgatgtcgcg aacggacgtg gcgcccgacg ccgatttctt ccggatcggc
    26701 gggaattcgc tgctgagcgc gcaactgaca ttcatgcttc aaaagcagtt ctcggtgacg
    26761 ctcagcatcg ccgacgtgtt ccgccatcgg acgatcgacg cgctcgcggc gatcattcgc
    26821 gaacgatccc aaaaggccgc gaagacggcg cctgcggctg ccggccaacc gccggcggcg
    26881 acgcagtcga cccccggcag cgcaggcgcc gcggaccgga tcgtattcgc gacgcccgcg
    26941 cagcgcggga tctggctgct cgaaaacagc cccggcggcc gggcggtgtc gaacgcgccg
    27001 ctcgtgttcg attacgcggg cacgctcgac cgcgcgctgc tcgagcgatg cgtggcgcaa
    27061 ctgctcgagc gccatgcgat cctgcgcagc aactacgtgt gggaggacgg cagcctgcgg
    27121 atcaagtgca acgcgcgcgc gtcgtttcgc atcgagtcgg tcgatctcgg atcgcagacg
    27181 cccgacgcgc aacgggcgaa ggcgggcgag ctggtcgcgc gggaggtgat gcgcccgttc
    27241 gatctgcggc gcgatccgat gctgcgcgtg accgatatcg cgttcggcga gcgcgccgga
    27301 caactggtgt tcgtgttcca ccacatcgcg gtcgacgatc gggcgctgaa catcgtgttc
    27361 tccgaattgc agcggctcta caacgcgggc ggggacccga cggcgatcgg cgccgcgccc
    27421 gcccggcagt tcgccgacta cgcggcggcg gcgcgcgatg cgaacgcgcg gctcggcgcg
    27481 aatctcgatt actggcggca caagctggcc gattaccgcg gcgcgacgcc gtatctggtc
    27541 gacgcgcagg cgaagcccgc gtcgcggttc gccgggcggc tccatttcca tagcgtcgcg
    27601 caggacgtga gccggaacct cgaagcgggc gccgcgcgcc gcgggctcac gccgttcgcg
    27661 ctgttcgcgg ccgccgtcgc gtgcatcgtg caccgcgcgt ccggcagcga cgacgtgacg
    27721 atcggcacgt tcttctcgaa tcgcgatcac ttccaggaca acgagctcgt cggcttcttc
    27781 gtcaatacgc tgccgctgcg catgcgaatc gattccggct gggatgtcga tcagctcgcg
    27841 caggcggtgt cggcgacgct cgcggacgcg cattcgcatc gcgacgtggc gaccgaggac
    27901 gtgttcgacg cattgcggat caacaacacg ctgcgccgcg cggcgttccg ggtgatggtc
    27961 aacctcgagc ccgagcaggc ggaggtgctg acgatgggcg cgctgacggc ccgccgggcg
    28021 ctgctcgacc ggcatgtcgc gaagtacgac ttgctcttct cgttgcgcaa ggaggacggg
    28081 gactatcgcg tgctcgtcga atacaacacg gatctctacg acggcgacgt cattgcgagg
    28141 gtctgcgcga atctcgaccg ggcgctcgcg gcgctgacgg gcgcgacgcg cgagcggctc
    28201 gccgcgattg cgctgccgaa tccgctcgag cccggcgagc cgggcggcga ggccgccgat
    28261 gcgaagccga aggcggccgc cgacctcgat ctgcgcgcgg tggttcgcga catctgggcg
    28321 agcgaggtcg gcaaccggac gttcggcgac gacgagaact tcttcgacgt cggcggcagc
    28381 tcgctcaaga tcatgacggt ctacgaaaag ctgtcgagct tcctgaagga caacggcttc
    28441 gagaaggaaa tcgacatcgt cgatctgttc gagcacgtga ccgtcgcgac gctgaccgat
    28501 ttcctcgggg aattgatcga acatgacgca ctcgcacagt gacgtgggcg cgcgcccttc
    28561 cggcgcgccg gagggccgcc cgatggacat cgcgatcgtc ggcgtgagcg cgcgcgtgcc
    28621 gggcgcgcgc gacgtcgacg cgctgtggtc gctgctgatg tcgggcggcg acgggctcac
    28681 gacgttcgag ccgcacgagc tcgcggccga gctcgcgccg ctcggcgatg ccgagcgggc
    28741 gcgctacgtt ccgcggcggg gcgtgctcga cggcatcgaa gcgtgcgacg cgggcttctt
    28801 caacctgtcg gcggcggagg cgacgctgct cgatccgcag catcgcgtgc tgatggagct
    28861 tgtatgggag gcgctcgagg acgcgggcgc ggccgattgc gcggggcgca acgtcggcgt
    28921 gttcacgacg tcggggctga gccactacct gatcaagcat ctgctgcccg acccggcgat
    28981 cagcgagcgg cacgggcagt tgcaactgct gatgctcaac gacaaggatt ttctcgcaac
    29041 ccgcatcgcg tacttcctga acgtgcacgg gcccgccgtc aacgtgcaga ccgggtgctc
    29101 cagctcgctc gtcgcgctgc actatgcgtg cctgtcgctg ctgcggcgcg attgcgaaat
    29161 ggccgtcgtc ggcggcgtgt cgatcgcgct gccgcagcag gcgggctacg tgttctcgga
    29221 gaacatgatc ggctcgcgcg acggcttttg ccgcgcgttc gacagcgacg cgtcgggcac
    29281 cgtgcgcggc aacggcgcgt gcgcggtcgt gctcaagccg ctcgccgagg cgctcgcgga
    29341 ccgcgatccg gtgtgggcgg tgatcaaggg cacggcgctc aacaacgacg ggcgcgacaa
    29401 ggtcgggttc accgcgccga gcccgaagtg gcaggcggac gtgatcgatg ccgtctatcg
    29461 ccgaagcggc gtcgcgctcg acgacgtcga tttcgtcgaa gcgcacggca cgggcacacc
    29521 gctcggcgat ccgatcgagg cgagggcgat caatcaggtg ttcgcgcgcg cgggcgcgcg
    29581 ccggccgcgt tatctcggcg cgctgaaaac ccagatcggg catctggata cggcggcggg
    29641 cctcgccggg ttgatcaagc tgtgcgttgc gctgcgaaac ggcacgattc cgccgacctc
    29701 gcactttcga acattgaatc cgcgcatctc gctcgacgat tcgcagttca cgatcaacac
    29761 cgagcccgtc gcgtggccca gacgcgacgc gccgcgatac gccgcgctca gttcgttcgg
    29821 catcggcggc accaacgcgc acgtggtcgt cgcggacgcg ccggcgggcg agcgggcacc
    29881 ggcggcggga agtgcggcaa gcgtggaaag cgccgaaagc ggcccgcatc tgatcgtcgt
    29941 gtcggcgaag agcgccgcct cgctcgatgc gctgaggaac gcctacgcgg acgcgatcgc
    30001 ggcgctcgac gacgcggcgc tcgcggattt cgcttactcg acgcgcgtcg gccgccgcgg
    30061 cttcgagcat cggctggccg tctgcgccga cggtcgcgcg gacgcggtcg agcaactgcg
    30121 cgcggcgcgc gcgcgattca ctgcgaagac ggtggagggc gtgagcgtcg cggctgccga
    30181 cgcgccttcg atcgcggcgc ggctcggcat cgcgtcgccc gagcgcgcgg aacgcccggt
    30241 tgaagcgatc gccgcgcggc tcgccgagct gggcgtcgcg atcgacgcgg gcgcggcggt
    30301 ccggcttggc attgccgacg gccggcttca cgtcgtcacg ccggacgcgt ggtccgaggc
    30361 gatcgacgcc gcgacgccgg acgccaccgg ccgccatctg caggcggcgc tgtggcgcgc
    30421 gggcgtggcg gtcgatttcg gccgcgacac cggctcggcg gcgcgcagac gaatccggat
    30481 tccgacttac cggttcgacc ggcagcgaca ctggatcgac gccccgtgca gccggcatgg
    30541 cgacggccgc gacagccagt ccgccggcga cgccgcgccg gatgcgcggc gccggatgcc
    30601 gcccgccgag cagccgacga gcctcgtcgc gctcgaagcg gcgctgctgt cgcactggcg
    30661 cggcttgctg ggattgccga cgcttcgcag caccgacaac gttttcgagc aaggcgcgga
    30721 ttcgctcacg gtcgcgcagt tcgtcgcgca actgacgtcg gagcgcgcgc tgcccgtgca
    30781 cgtcgtcgac tgctacagcg agccgagcgt gggcggccag gcgcgcctcg tcggcgcgcg
    30841 catcgggctg ggcggccccg ccgcggcggc agcgcaagcg agcgcgccgg cacccgaagt
    30901 cgagagattt gacaaccttt aaagcgagat tgcagtgacg agccaatatt tcctcaagaa
    30961 gaacgtcaag atcgagccgc tggtcaatcg ctggcacgcc aatccgtggc tcgtgtatcc
    31021 gccgacggcg gcttatctga tgcggcatca cctggacatc atgacgtcgt tcgtcaagca
    31081 cgcggcgctg cacgagaagg cggccgggag ccggaagatt cgcggcggac cgttcgtgca
    31141 gggactcggc gcggacgacg tgccggcgat ggaggcgctg atcgaggcga cgcggcgaga
    31201 cggcgcccat ctgttcgggc tcgccgacga tctcgacgcg ctgcgcgcgg cgctcggcgc
    31261 ggccgacggc catagcctcg ttccgttcta cgaacaggtg ccgcctcgct tgcgcgggat
    31321 ggtcgagctc gcgtatcagg cgggcaacca cgcatatgcg cggctcatgg aagggctgta
    31381 ctacgacgca tacgacacga gcgcgctgca gtcgttcgcg ctggcgccgc tgtgggacga
    31441 cagccggccg ttctgcctca gcacgccgcg gctcgacacg agcggcgacg tgctgctcga
    31501 cattccgttc gcggacccgc tcgcggtcgc gctgacggcg tcgcgccgca acggcctcac
    31561 gcccgcgcaa ttcgaggcga ttctcgatcg ccgctcgaag ggcacgcgcg ccgacgccgt
    31621 cgccgcgctc ttctcggacg ccgcgccgga gcaccgcccg gccgaagcgc acgagccgcg
    31681 cgtgcgctac ttcggccacg cgtgcgtgct cgtgcagacc ggcacggaaa acctgctgtt
    31741 cgatccgctg atcagctacc cgtttcccgg ccagtcgccg cgcttcacgt tcgacgattt
    31801 gcccgacgtg atcgactacg tcgtgatcac ccattcgcat cacgatcact tcgtgctcga
    31861 gacgctgctg cagatccgcg atcgcgtgaa gacgatcgtc gtgccgcaga acacgcacgg
    31921 gcaactgatg gacccgtcgc tcaagcacgc ggcgcacgcg ctcggattcg agaacgtcat
    31981 catgatgagc gagttcgaca cgctcaagct cggcggcggc aagctgcacg cggtgccgtt
    32041 cctcggcgag cacggcgatc tcgacatccg cagcaagctc gggtttctcg tcgaggcggg
    32101 cgatcggcgc gtgctgatgg tcgcggacag caacaatctc gacgacaggc tgtacgaaca
    32161 catccgccgc cgctacggca aggtcgacct gctgttcatc ggcatggagt gcgagggcgc
    32221 gccggtgtcg tggctgtacg ggccgatgct gaacacgaag ctcgcgcgat cgatggacga
    32281 cagccggcgt ctcaacggct ccggctccag cgccggcttc cggctggccg agatcgtcgg
    32341 cgcggatcgc gtgttcatct atgcgatggc acaggagccg tggctcacgt tcatcagcag
    32401 cctcgaatac gacgagagct cgttcgcgat gcgcgaggcg agaaagatga tcgacgcgtg
    32461 caggcaggcg aacgtcgacg cgtgcctgct caacggctgc gtcgacattc cgttgcgcgc
    32521 gcggtgaccg gatggatcgc gctcatcgag aatcggcgag tccggtcgag acgttgctcg
    32581 acggcatgat cgggaagaac gcgtattttc cgcgccgcat cggcggcgcg atgcgcgtgc
    32641 atgcactcgg cgatcatgcg gtcgtcaaca gcgggctcgc gaccgacacg ttcaatctgg
    32701 tcatcagccg ggcggccgac ggggcgcagg cgaacgcggt cgcgccgatc gcgcgcgact
    32761 tcgacgaagc cggcctgccg gccgcatggt ggacttgccg cagcgggccg gacgccgcgt
    32821 tctcgcgagc gctcggcgac gcgggattcg tcgacgacga aacgagcgtc gggatgctcg
    32881 ccgagctgga cgcgctgccg tgcgtcgagc ctccgcgcgg attccgggtg cgccagatca
    32941 gcgaggcggg cgacgtcgcg cgcttcggcg cgctgatctg cgcgctgttc gatccgcccg
    33001 atccgttcgt cgacgcgttc tatctgcacg tcgccgcgct ggagatcgac accgccgagc
    33061 cgctgaagct gttcatcggc gagatcgacg gccgcgcggt cagcacggcc gcgctctatc
    33121 tcgatgccgg caccgcgcac gtgttcgaca tcagcacggc ggcgcacgcg cgaaggcgcg
    33181 gctatgcgcg cgccatcacc cacttcgtgc tcgcgcatgc gagagaccgg ctcggcgcgg
    33241 accgcgcggc gctgcaggcg tcgccggaag gtctgaacgt ctatcggcgt ctcggctttc
    33301 ggccggtgtg cgagtttcgc gtgtattcga accgcgccgc ggttctggag agaagccatg
    33361 accagcatcc ccgttagact cgatcagttt ccgcccgccg ccgatccggc cgccccggcg
    33421 gcggcgtttc ccgctccggc cgcgaaggcc gcgatccgca cgctggttgc gccgtcgccc
    33481 ggcggcgcgc acgtgctgtg cattccatgg gccggcgcga gcatcgagcg cttcttcgcg
    33541 tggaagcggc atctgccggc gggcgtcggt ttgtcgggcg tccagttgcc cggacgcggg
    33601 gcgcgcgcgc acgagccgtc gccgacggat ctcgtcgcgc tgctcgacga gatcgcggcc
    33661 gaatacctcg cgctgcccga tccgccgcgc atcctgttcg ggcatagctt cggcgcgctg
    33721 atcgcgttcg agatcgcgac gcgcgtgagc cgcgcggccg gccaggcggg cggcgatccg
    33781 ttcgtgcggc tcgtcgtgtc ggggctgtcc gcgccgagcg tgatcgccga ggaaaagcgg
    33841 atcgcccatc tcgacgacga cgcgttcagc gcggaagtgc acgcgctcaa cggaatgccg
    33901 cctgaaatcg cgcgcagccc cgaatcgctg cgctacttca tggccgtcct gcgatgcgat
    33961 ttccggctgt acgaatcgta ttcgttcgac gcggatcgtc cgccgctgcg ctgtccgatc
    34021 gccgtgtgct ccggccgcga cgatccgagc gtgtcggagc acgggctgaa cgcgtgggcc
    34081 gcgctcacga cgggcgagtg ccggcgtcac gatttcgacg gcgatcactt cttcatcgcg
    34141 gaccacgcgg ccgcgatgct cggcctcgcg ctggacgccg aaagcacgct cgtcggctga
    34201 gcggcgccgc ctttctttcc attccttttc tcgaatcgtc atttcctgtc gaccacgttc
    34261 atgagcgaga cttcgaagcg ccatccatcc ctcgtgttga tcctgattcc ggtcgtgatg
    34321 ctcggccagc tctcgatgga catgtatctg cccgcgctcg gcagcctgca ggcgagcatg
    34381 cgcgcgacgg gcagcgagct ccagatgacg ctcagcgcgt tcgtcgtgtc gctcggcgta
    34441 tcgcagttcc tcgtcggcga gttcgcgcgc cgcgccgggc gagggcgcgc gatccggatc
    34501 gcgctcgtcg gcttcgtttg cgcgacggcc ggctgcgcgg tcacgtcgtc gatcgcgctc
    34561 ttcatcgtct gccgcgcggt tcagggcatc gcggcggcgg tgtgcgtcgc gctgtcgtac
    34621 gcggtgatcg ccgataacgc gaaggacagc cacgaaagca tgcgcgggat gacgatgctc
    34681 accgtcgcgt cgacggtcgc gccgctgatc gcgccggtgg cgggctccca ggtgcttcag
    34741 ctcgccggct cgtggcgggc cgtcttcatg ctgctgctgt gcgtcgcgat cgtcgcggtt
    34801 ctcgcgttct tcgcgcaacc ggcggcccgc ttcgatgcgc gcgcgcacga tgcgtcgaag
    34861 ccggcccgca agatctatct cgggatcgtg acgtcttcgc aattctggcg ctatgcgctg
    34921 ctttgctcga tcggcacgac gatcaatttc tgcttcttct cgttcctgcc cggcatcctg
    34981 ctggttcaga acgggcttac gcagaaccag ttttccgccg cgttcttcct gtgcgggctg
    35041 accgagatcg cgggctcgct gctcgcgccg cggatcagca aactgatcgg ccctccggga
    35101 ctggcggggc tcgcctgcgt ctgctgcgcg ctcggcggct tcggcgtcgc ctatttttcg
    35161 acgacgccaa atgccgtcgt gccgatcgtc gccgcgttct cgatcgtcga gctgggaacc
    35221 ggcatgctga tcgcgccgtg cttctccgcg gcgctgtacc tgttccgctc gacgtccaac
    35281 gaagcgtccg cgatctgcgg tttccagcaa ttcatgatcg cggccggcgt cgcgacgttc
    35341 gccgccgcga tgaagtggca atcgtcgtac gcgctcggca tcctgatcgg cgtcgccgcg
    35401 ctgatcggcg cggcgctctg cggcacgctg ccggggggcg cgcaagccga cgagcagacg
    35461 gcgggggtgc cgctgaattc agactagcgt tcggccggat tcgattcgcc ccgcgcgtgt
    35521 cgcggggcga tcgtccgggg aagcgggcaa ggcggtggaa tgagcccgct cgggaaagcc
    35581 gcgacggaag gcgagagaag aagttggtgg aagaggctgg tgagcaagag gctggtgagc
    35641 aagaggctgg tgagatgggc cgcccggcga atcgcccggc aatcggcgaa tgatcgacgg
    35701 cttcgcgaaa tcgaccgatt gccggcgtgc ccgtttggcg cttgccggct tactgataga
    35761 acggcttcgg gccggacacc atcacgcgcc gcatgatgcg attgccgacg ggcggattcg
    35821 gcgagttggt gtggatcagc gatgcgttgt cccagatcac gaggtcttcg ttcgtgtagc
    35881 gatggcggta gatgaaatcc tcgttgcggc aatgcgcgaa gatgcgatcg aggatctcgt
    35941 cgctttcctc gtgtgaatag ccttcgatcc ggtccgtgtg cgcccagttg acgaagatcg
    36001 agcgtcggcg cgtatgcgga tgggtgcgca ccgcgggatg cgagacggtc ggcttgaaat
    36061 cgtcttccgc gatgttgaga tcgaagccga tcttcctgca tcgcttcacg aggctgctgt
    36121 cgagactgaa gatcgcgttc ctgccgtcga tcgccgactt cagttcgtcg ggaagcgtct
    36181 cgtacgcggc gaacatgttc gcgaaccagg tgtcgccatg cgcatcgggc accgattcgg
    36241 cgtagaagaa cgtcattttc gccggatgtt cgagatagca cagatccgaa tgccagagct
    36301 cgaacggcgg cgtcgggtag cctaccggct tgccgtccgt cgtcacgttc gacacgatcg
    36361 tcatttccgg gaacgaagac gtgttggtcg tcatcgggtg cggttcgagc tcgccgaaat
    36421 cccggcacgc ggcgacttgc tgctcgcacg acaggcgctg gccgggaaac acgagcaatt
    36481 gatgttcgga caacaaaccg atgatgtcgt cgcgcgtctg cgacgacagc ggttgcgaaa
    36541 aatcgatgcc tcgaatctct gcgccgagcg caggggacaa tttgcgtgaa atcat
//
