LOCUS       BGC0000978             42156 bp    DNA     linear   BCT 19-FEB-2008
DEFINITION  Cylindrospermopsis raciborskii AWT205 cylindrospermopsin
            biosynthesis gene cluster, complete sequence.
ACCESSION   BGC0000978
VERSION     BGC0000978
KEYWORDS    .
SOURCE      Cylindrospermopsis raciborskii AWT205
  ORGANISM  Cylindrospermopsis raciborskii AWT205
            Bacteria; Cyanobacteria; Nostocales; Aphanizomenonaceae;
            Cylindrospermopsis.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 21:27:22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 42156
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..42156
                     /db_xref="taxon:478021"
                     /mol_type="genomic DNA"
                     /organism="Cylindrospermopsis raciborskii AWT205"
                     /strain="AWT205"
     protocluster    1..42156
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[19302:28056]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      19303..28056
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..42156
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[443:39302]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      444..39302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..42156
                     /SMILES="C=CCC(=O)NC([*])C(=O)C(C)=CC=CCC(O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..42156
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000978"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..42156
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            444..6074
                     /gene="cyrD"
     CDS             444..6074
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (64-484). E-value:
                     7.8e-183. Score: 600.0. Matches aSDomain:
                     nrpspksdomains_cyrD_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (590-885). E-value: 7.8e-106.
                     Score: 345.6. Matches aSDomain:
                     nrpspksdomains_cyrD_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (976-1201). E-value: 8.4e-24.
                     Score: 76.1. Matches aSDomain:
                     nrpspksdomains_cyrD_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (1465-1639). E-value: 2e-62.
                     Score: 202.2. Matches aSDomain:
                     nrpspksdomains_cyrD_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1730-1813). E-value: 1.7e-17.
                     Score: 55.4. Matches aSDomain:
                     nrpspksdomains_cyrD_PKS_PP.1"
                     /codon_start=1
                     /gene="cyrD"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 282.1; E-value:
                     1.3e-85)"
                     /gene_kind="biosynthetic"
                     /note="CyrD"
                     /product="polyketide synthase"
                     /protein_id="ABX60152.1"
                     /sec_met_domain="PP-binding (E-value: 8.2e-11, bitscore:
                     32.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2e-106, bitscore: 345.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 8.9e-197, bitscore:
                     643.9, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 4.8e-58, bitscore:
                     185.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSKFNINVTLLVCLIIIPYFPTTLMKVPITANEDAATLLQRVGL
                     SLKEAHQQLEAMQRRAHEPIAIVGLGLRFPGADSPQTFWKLLQNGVDMVTEIPSDRWAV
                     DEYYDPQPGCPGKMYIREAAFVDAVDKFDASFFDISPREAANIDPQHRMLLEVAWEALE
                     RAGIAPSQLMDSQTGVFVGMSENDYYAHLENTGDHHNVYAATGNSNYYAPGRLSYLLGL
                     QGPNMVVDSACSSSLVAVHLACNSLRMGECDLALAGGVQLMLIPDPMIGTAQLNAFATD
                     GRSKTFDAAADGYGRGEGCGMIVLKRISDAIVADDPILAVIRGSAVNHGGRSSGLTAPN
                     KLSQEALLRQALQNAKVQPEAVSYIEAHGTGTQLGDPIEVGALTTVFGSSRSEPLWIGS
                     VKTNIGHLEPAAGIAGLIKVILSLQEKQIPPSLHFQNPNPFIDWESSPVQVPTQCVPWT
                     GKERVAGVSSFGMSGTNCHLVVAEAPVRQNEKSENAPERPCHILTLSAKTEAALNALVA
                     RYMAFLREAPAISLADLCYSANVGRNLFAHRLSFISENIAQLSEQLEHCPQQATMPTQH
                     NVILDNQLSPQIAFLFTGQGSQYINMGRELYETQPTFRRIMDECDDILHPLLGESILNI
                     LYTSPSKLNQTVYTQPALFAFEYALAKLWISWGIEPDVVLGHSVGEYVAACLAGVFSLE
                     DGLKLIASRGCLMQALPPGKMLSIRSNEIGVKALIAPYSAEVSIAAINGQQSVVISGKA
                     EIIDNLAAEFASEGIKTHLITVSHAFHSPMMTPMLKAFRDVASTISYRSPSLSLISNGT
                     GQLATKEVATPDYWVRHVHSTVRFADGIATLAEQNTDILLEVGPKPILLGMAKQIYSEN
                     GSASHPLMLPSLREDGNDWQQMLSTCGQLVVNGVKIDWAGFDKDYSRHKILLPTYPFQR
                     ERYWIESSVKKPQKQELRPMLDKMIRLPSENKVVFETEFGVRQMPHISDHQIYGEVIVP
                     GAVLASLIFNAAQVLYPDYQHELTDIAFYQPIIFHDDDTVIVQAIFSPDKSQENQSHQT
                     FPPMSFQIISFMPDGPLENKPKVHVTGCLRMLRDAQPPTLSPTEIRQRCPHTVNGHDWY
                     NSLVKQKFEMGPSFRWVQQLWHGENEALTRLHIPDVVGSVSGHQLHGILLDGSLSTTAV
                     MEYEYGDSATRVPLSFASLQLYKPVTGTEWWCYARKIGEFKYDFQIMNEIGETLVKAIG
                     FVLREASPEKFLRTTYVHNWLVDIEWQAQSTSLVPSDGTISGSCLVLSDQHGTGAALAQ
                     RLDNAGVPVTMIYADLILDNYELIFRTLPDLQQVVYLWGLDQKEDCHPMKQAEDNCTSV
                     LYLVQALLNTYSTPPSLLIVTCDAQAVVEQDRVNGFAQSSLLGLAKVIMLEHPELSCVY
                     MDVEAGYLQQDVANTIFTQLKRGHLSKDGEESQLAWRNGQAYVARLSQYKPKSEQLVEI
                     RSDRSYLITGGRGGVGLQIARWLVEKGAKHLVLLGRSQTSSEVSLVLDELESAGAQIIV
                     AQADISDEKVLAQILTNLTVPLCGVIHAAGVLDDASLLQQTPAKLKKVLLPKAEGAWIL
                     HNLTLEQRLDFFVLFSSASSLLGAPGQANYSAANAFLDGLAAYRRGRGLPCLSICWGAW
                     DQVGMAARQGLLDKLPQRGEEAIPLQKGLDLFGELLNEPAAQIGVIPIQWTRFLDHQKG
                     NLPFYEKFSKSSRKAQSYDSMAVSHTEDIQRKLKQAAVQDRPKLLEVHLRSQVAQLLGI
                     NVAELPNEEGIGFVTLGLDSLTSIELRNSLQRTLDCSLPVTFAFDYPTIEIAVKYLTQV
                     VIAPMESTASQQTDSLSAMFTDTSSIGRILDNETDVLDSEMQSDEDESLSTLIQKLSTH
                     LD"
     misc_feature    444..42048
                     /note="cylindrospermopsin biosynthesis gene cluster"
     aSDomain        636..1895
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrD_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="7.80E-183"
                     /label="cyrD_PKS_KS.1"
                     /locus_tag="cyrD"
                     /protein_end="484"
                     /protein_start="64"
                     /score="600.0"
                     /tool="antismash"
                     /translation="IAIVGLGLRFPGADSPQTFWKLLQNGVDMVTEIPSDRWAVDEYYD
                     PQPGCPGKMYIREAAFVDAVDKFDASFFDISPREAANIDPQHRMLLEVAWEALERAGIA
                     PSQLMDSQTGVFVGMSENDYYAHLENTGDHHNVYAATGNSNYYAPGRLSYLLGLQGPNM
                     VVDSACSSSLVAVHLACNSLRMGECDLALAGGVQLMLIPDPMIGTAQLNAFATDGRSKT
                     FDAAADGYGRGEGCGMIVLKRISDAIVADDPILAVIRGSAVNHGGRSSGLTAPNKLSQE
                     ALLRQALQNAKVQPEAVSYIEAHGTGTQLGDPIEVGALTTVFGSSRSEPLWIGSVKTNI
                     GHLEPAAGIAGLIKVILSLQEKQIPPSLHFQNPNPFIDWESSPVQVPTQCVPWTGKERV
                     AGVSSFGMSGTNCHLVVAEAP"
     aSModule        636..5882
                     /complete
                     /domains="nrpspksdomains_cyrD_PKS_KS.1"
                     /domains="nrpspksdomains_cyrD_PKS_AT.1"
                     /domains="nrpspksdomains_cyrD_PKS_DH2.1"
                     /domains="nrpspksdomains_cyrD_PKS_KR.1"
                     /domains="nrpspksdomains_cyrD_PKS_PP.1"
                     /locus_tags="cyrD"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1113..1160
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0001"
                     /evalue="7.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrD"
                     /protein_end="239"
                     /protein_start="223"
                     /score="18.1"
                     /tool="antismash"
                     /translation="GPNMVVDSACSSSLVA"
     CDS_motif       1302..1340
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0002"
                     /evalue="7.50E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="cyrD"
                     /protein_end="299"
                     /protein_start="286"
                     /score="12.7"
                     /tool="antismash"
                     /translation="FDAAADGYGRGEG"
     CDS_motif       1533..1580
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0003"
                     /evalue="7.80E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrD"
                     /protein_end="379"
                     /protein_start="363"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YIEAHGTGTQLGDPIE"
     CDS_motif       1635..1679
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0004"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrD"
                     /protein_end="412"
                     /protein_start="397"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEPAAG"
     aSDomain        2214..3098
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrD_PKS_AT.1"
                     /evalue="7.80E-106"
                     /label="cyrD_PKS_AT.1"
                     /locus_tag="cyrD"
                     /protein_end="885"
                     /protein_start="590"
                     /score="345.6"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYINMGRELYETQPTFRRIMDECDDILHPLLGESILNI
                     LYTSPSKLNQTVYTQPALFAFEYALAKLWISWGIEPDVVLGHSVGEYVAACLAGVFSLE
                     DGLKLIASRGCLMQALPPGKMLSIRSNEIGVKALIAPYSAEVSIAAINGQQSVVISGKA
                     EIIDNLAAEFASEGIKTHLITVSHAFHSPMMTPMLKAFRDVASTISYRSPSLSLISNGT
                     GQLATKEVATPDYWVRHVHSTVRFADGIATLAEQNTDILLEVGPKPILLGMAKQIYSEN
                     GSASHPLMLPSLRE"
     CDS_motif       2217..2264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0005"
                     /evalue="8.30E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrD"
                     /protein_end="607"
                     /protein_start="591"
                     /score="21.2"
                     /tool="antismash"
                     /translation="FTGQGSQYINMGRELY"
     CDS_motif       2388..2438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0006"
                     /evalue="6.20E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrD"
                     /protein_end="665"
                     /protein_start="648"
                     /score="13.0"
                     /tool="antismash"
                     /translation="TQPALFAFEYALAKLWI"
     CDS_motif       2445..2567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0007"
                     /evalue="3.40E-28"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrD"
                     /protein_end="708"
                     /protein_start="667"
                     /score="90.1"
                     /tool="antismash"
                     /translation="GIEPDVVLGHSVGEYVAACLAGVFSLEDGLKLIASRGCLMQ"
     CDS_motif       2658..2696
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0008"
                     /evalue="7.10E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrD"
                     /protein_end="751"
                     /protein_start="738"
                     /score="12.9"
                     /tool="antismash"
                     /translation="AAINGQQSVVISG"
     CDS_motif       2916..2951
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0009"
                     /evalue="4.40E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="cyrD"
                     /protein_end="836"
                     /protein_start="824"
                     /score="10.6"
                     /tool="antismash"
                     /translation="YWVRHVHSTVRF"
     aSDomain        3372..4046
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrD_PKS_DH2.1"
                     /evalue="8.40E-24"
                     /label="cyrD_PKS_DH2.1"
                     /locus_tag="cyrD"
                     /protein_end="1201"
                     /protein_start="976"
                     /score="76.1"
                     /tool="antismash"
                     /translation="ISDHQIYGEVIVPGAVLASLIFNAAQVLYPDYQHELTDIAFYQPI
                     IFHDDDTVIVQAIFSPDKSQENQSHQTFPPMSFQIISFMPDGPLENKPKVHVTGCLRML
                     RDAQPPTLSPTEIRQRCPHTVNGHDWYNSLVKQKFEMGPSFRWVQQLWHGENEALTRLH
                     IPDVVGSVSGHQLHGILLDGSLSTTAVMEYEYGDSATRVPLSFASLQLYKPVTGTEWWC
                     YAR"
     CDS_motif       3375..3446
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0010"
                     /evalue="1.70E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="cyrD"
                     /protein_end="1001"
                     /protein_start="977"
                     /score="17.4"
                     /tool="antismash"
                     /translation="SDHQIYGEVIVPGAVLASLIFNAA"
     CDS_motif       4839..4937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0011"
                     /evalue="2.20E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="cyrD"
                     /protein_end="1498"
                     /protein_start="1465"
                     /score="52.3"
                     /tool="antismash"
                     /translation="SYLITGGRGGVGLQIARWLVEKGAKHLVLLGRS"
     aSDomain        4839..5360
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrD_PKS_KR.1"
                     /evalue="2.00E-62"
                     /label="cyrD_PKS_KR.1"
                     /locus_tag="cyrD"
                     /protein_end="1639"
                     /protein_start="1465"
                     /score="202.2"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="SYLITGGRGGVGLQIARWLVEKGAKHLVLLGRSQTSSEVSLVLDE
                     LESAGAQIIVAQADISDEKVLAQILTNLTVPLCGVIHAAGVLDDASLLQQTPAKLKKVL
                     LPKAEGAWILHNLTLEQRLDFFVLFSSASSLLGAPGQANYSAANAFLDGLAAYRRGRGL
                     PCLSICWGAWD"
     CDS_motif       5205..5315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrD_0012"
                     /evalue="1.60E-22"
                     /label="PKSI-KR_m4"
                     /locus_tag="cyrD"
                     /protein_end="1624"
                     /protein_start="1587"
                     /score="72.1"
                     /tool="antismash"
                     /translation="LDFFVLFSSASSLLGAPGQANYSAANAFLDGLAAYRR"
     aSDomain        5634..5882
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrD_PKS_PP.1"
                     /evalue="1.70E-17"
                     /label="cyrD_PKS_PP.1"
                     /locus_tag="cyrD"
                     /protein_end="1813"
                     /protein_start="1730"
                     /score="55.4"
                     /tool="antismash"
                     /translation="KQAAVQDRPKLLEVHLRSQVAQLLGINVAELPNEEGIGFVTLGLD
                     SLTSIELRNSLQRTLDCSLPVTFAFDYPTIEIAVKYLT"
     gene            6130..10203
                     /gene="cyrF"
     CDS             6130..10203
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (37-455). E-value:
                     6.2e-181. Score: 593.7. Matches aSDomain:
                     nrpspksdomains_cyrF_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (553-855). E-value: 2.5e-107.
                     Score: 350.5. Matches aSDomain:
                     nrpspksdomains_cyrF_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (1004-1076). E-value: 3.7e-20.
                     Score: 63.9. Matches aSDomain:
                     nrpspksdomains_cyrF_PKS_PP.1"
                     /codon_start=1
                     /gene="cyrF"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 115.3; E-value:
                     4.7e-35)"
                     /gene_kind="biosynthetic"
                     /note="CyrF"
                     /product="polyketide synthase"
                     /protein_id="ABX60153.1"
                     /sec_met_domain="PP-binding (E-value: 4e-15, bitscore:
                     46.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.3e-108, bitscore:
                     350.5, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 9.7e-196, bitscore:
                     640.5, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALSENQVTSIVKKALNKIEELQAELDRLKYAQREPIAIIGMGC
                     RFPGADTPEAFWKLLHNGVDAIQEIPKSRWDIDDYYDPTPATPGKMYTRFGGFLDQIAA
                     FDPEFFRISTREAISLDPQQRLLLEVSWEALERAGLTGNKLTTQTGVFVGISESDYRDL
                     IMRNGSDLDVYSGSGNCHSTASGRLSYYLGLTGPNLSLDTACSSSLVCVALAVKSLRQQ
                     ECDLALAGGVQIQVIPDGFIKACQSRMLSPDGRCKTFDFQADGYARAEGCGMVVLKRLS
                     DAIADNDNILALIRGAAVNHDGYTSGLTVPSGPSQRAVIQQALADAGIHPDQISYIEAH
                     GTGTSLGDPIEMGAIGQVFGQRSQMLFVGSVKTNIGHTEAAAGIAGLIKVVLSMQHGEI
                     PANLHFDQPSPYINWDQLPVSIPTETIPWSTSDRFAGVSSFGFSGTNSHIVLEAAPNIE
                     QPTDDINQTPHILTLAAKTPAALQELARRYATQIETSPDVPLADICFTAHIGRKHFKHR
                     FAVVTESKEQLRLQLDAFAQSGGVGREVKSLPKIAFLFTGQGSQYVGMGRQLYENQPTF
                     RKALAHCDDILRAGAYFDRSLLSILYPEGKSEAIHQTAYTQPALFALEYAIAQLWHSWG
                     IKPDIVMGHSVGEYVAACVAGIFSLEDGLKLIATRGRLMQSLPQDGTMVSSLASEARIQ
                     EAITPYRDDVSIAAINGTESVVISGKRTSVMAIAEQLATVGIKTRQLTVSHAFHSPLMT
                     PILDEFRQVAASITYHQPKLLLVSNVSGKVAGPEITRPDYWVRHVREAVRFADGVRTLN
                     EQGVNIFLEIGSTATLLGMALRVNEEDSNASKGTSSCYLPSLRESQKDCQQMFTSLGEL
                     YVHGYDIDWGAFNRGYQGRKVILPTYPFQRQRYWLPDPKLAQSSDLDTFQAQSSASSQN
                     PSAVSTLLMEYLQAGDVQSLVGLLDDERKLSAAERIALPSILEFLVEEQQRQISSTTTP
                     QTVLQKISQTSHEDRYEILKNLIKSEIETIIKSVPSDEQMFSDLGIDSLMAIELRNKLR
                     SAIGLELPVAIVFDHPTIKQLTNFVLDRIVPQADQKDVPTESLFASKQEISVEEQSFAI
                     TKLGLSPASHSLHLPPWTVRPAVMADVTKLSQLEREAYGWIGEGAIAPPHLIADRINLL
                     NSGDMPWFWVMERSGELGAWQVLQPTSVDPYTYGSWDEVTDQGKLQATFDPSGRNVYIV
                     AGGSSNLPTVASHLMTLQTLLMLRETGRDTIFVCLAMPGYAKYHSQTGKSPEEYIALTD
                     EDGIPMDEFIALSVYDWPVTPSFRVLRDGYPPDRDSGGHAVSTVFQLNDFDGAIEETYR
                     RIIRHADVLGLERG"
     aSDomain        6241..7494
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrF_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="6.20E-181"
                     /label="cyrF_PKS_KS.1"
                     /locus_tag="cyrF"
                     /protein_end="455"
                     /protein_start="37"
                     /score="593.7"
                     /tool="antismash"
                     /translation="IAIIGMGCRFPGADTPEAFWKLLHNGVDAIQEIPKSRWDIDDYYD
                     PTPATPGKMYTRFGGFLDQIAAFDPEFFRISTREAISLDPQQRLLLEVSWEALERAGLT
                     GNKLTTQTGVFVGISESDYRDLIMRNGSDLDVYSGSGNCHSTASGRLSYYLGLTGPNLS
                     LDTACSSSLVCVALAVKSLRQQECDLALAGGVQIQVIPDGFIKACQSRMLSPDGRCKTF
                     DFQADGYARAEGCGMVVLKRLSDAIADNDNILALIRGAAVNHDGYTSGLTVPSGPSQRA
                     VIQQALADAGIHPDQISYIEAHGTGTSLGDPIEMGAIGQVFGQRSQMLFVGSVKTNIGH
                     TEAAAGIAGLIKVVLSMQHGEIPANLHFDQPSPYINWDQLPVSIPTETIPWSTSDRFAG
                     VSSFGFSGTNSHIVLEAAP"
     aSModule        6241..9357
                     /complete
                     /domains="nrpspksdomains_cyrF_PKS_KS.1"
                     /domains="nrpspksdomains_cyrF_PKS_AT.1"
                     /domains="nrpspksdomains_cyrF_PKS_PP.1"
                     /locus_tags="cyrF"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6715..6759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0001"
                     /evalue="2.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrF"
                     /protein_end="210"
                     /protein_start="195"
                     /score="16.4"
                     /tool="antismash"
                     /translation="GPNLSLDTACSSSLV"
     CDS_motif       6904..6942
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0002"
                     /evalue="6.50E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="cyrF"
                     /protein_end="271"
                     /protein_start="258"
                     /score="9.9"
                     /tool="antismash"
                     /translation="FDFQADGYARAEG"
     CDS_motif       7135..7182
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0003"
                     /evalue="1.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrF"
                     /protein_end="351"
                     /protein_start="335"
                     /score="14.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       7234..7278
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0004"
                     /evalue="2.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrF"
                     /protein_end="383"
                     /protein_start="368"
                     /score="13.3"
                     /tool="antismash"
                     /translation="GSVKTNIGHTEAAAG"
     aSDomain        7789..8694
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrF_PKS_AT.1"
                     /evalue="2.50E-107"
                     /label="cyrF_PKS_AT.1"
                     /locus_tag="cyrF"
                     /protein_end="855"
                     /protein_start="553"
                     /score="350.5"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYVGMGRQLYENQPTFRKALAHCDDILRAGAYFDRSLL
                     SILYPEGKSEAIHQTAYTQPALFALEYAIAQLWHSWGIKPDIVMGHSVGEYVAACVAGI
                     FSLEDGLKLIATRGRLMQSLPQDGTMVSSLASEARIQEAITPYRDDVSIAAINGTESVV
                     ISGKRTSVMAIAEQLATVGIKTRQLTVSHAFHSPLMTPILDEFRQVAASITYHQPKLLL
                     VSNVSGKVAGPEITRPDYWVRHVREAVRFADGVRTLNEQGVNIFLEIGSTATLLGMALR
                     VNEEDSNASKGTSSCYLPSLR"
     CDS_motif       7792..7839
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0005"
                     /evalue="8.20E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrF"
                     /protein_end="570"
                     /protein_start="554"
                     /score="21.3"
                     /tool="antismash"
                     /translation="FTGQGSQYVGMGRQLY"
     CDS_motif       7975..8028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0006"
                     /evalue="2.40E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrF"
                     /protein_end="633"
                     /protein_start="615"
                     /score="14.3"
                     /tool="antismash"
                     /translation="TQPALFALEYAIAQLWHS"
     CDS_motif       8032..8154
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0007"
                     /evalue="7.30E-30"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrF"
                     /protein_end="675"
                     /protein_start="634"
                     /score="95.5"
                     /tool="antismash"
                     /translation="GIKPDIVMGHSVGEYVAACVAGIFSLEDGLKLIATRGRLMQ"
     CDS_motif       8248..8286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0008"
                     /evalue="1.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrF"
                     /protein_end="719"
                     /protein_start="706"
                     /score="12.4"
                     /tool="antismash"
                     /translation="AAINGTESVVISG"
     CDS_motif       8506..8541
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrF_0009"
                     /evalue="5.40E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="cyrF"
                     /protein_end="804"
                     /protein_start="792"
                     /score="16.5"
                     /tool="antismash"
                     /translation="YWVRHVREAVRF"
     aSDomain        9142..9357
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrF_PKS_PP.1"
                     /evalue="3.70E-20"
                     /label="cyrF_PKS_PP.1"
                     /locus_tag="cyrF"
                     /protein_end="1076"
                     /protein_start="1004"
                     /score="63.9"
                     /tool="antismash"
                     /translation="YEILKNLIKSEIETIIKSVPSDEQMFSDLGIDSLMAIELRNKLRS
                     AIGLELPVAIVFDHPTIKQLTNFVLDR"
     gene            10251..11687
                     /gene="cyrG"
     CDS             10251..11687
                     /codon_start=1
                     /gene="cyrG"
                     /note="CyrG; similar to aminohydrolase"
                     /product="putative uracil ring formation"
                     /protein_id="ABX60154.1"
                     /transl_table=11
                     /translation="MNKKQVDTLLIHAHLFTMQGNGLGYIADGAIAVQGSQIVAVDSTE
                     ALLSHFEGNKTINAVNCAVLPGLIDAHIHTTCAILRGVAQDVTNWLMDATIPYALQMTP
                     AVNIAGTRLSVLEGLKAGTTTFGDSETPYPLWGEFFDEIGVRAILSPAFNAFPLEWSAW
                     KEGDLYPFDMKAGRRGMEEAVDFACAWNGAAEGRITTMLGLQAADMLPLEILHAAKEIA
                     QREGLMLHIHVAQGDRETKQIVKRYGKRPIAFLAEIGYLDEQLLAVHLTDATDEEVIQV
                     AKSGAGMALCSGAIGIIDGLVPPAHVFRQAGGSVALGSDQACGNNCCNIFNEMKLTALF
                     NKIKYHDPTIMPAWEVLRMATIEGAQAIGLDHKIGSLQVGKEADLILIDLSSPNLSPTL
                     LNPIRNLVPNLVYAASGHEVKSVMVAGKLLVEDYQVLTVDESAILAEAQVQAQQLCQRV
                     TADPIHKKMVLMEAMAKGKL"
     gene            11741..12571
                     /gene="cyrI"
     CDS             11741..12571
                     /codon_start=1
                     /gene="cyrI"
                     /note="CyrI"
                     /product="proline dioxygenase-like protein"
                     /protein_id="ABX60155.1"
                     /transl_table=11
                     /translation="MTIYENKLSSYQKNQDAIISAKELEEWHLIGLLDHSIDAVIVPNY
                     FLEQECMTISERIKKSKYFSAYPGHPSVSSLGQELYECESELELAKYQEDAPTLIKEMR
                     RLVHPYISPIDRLRVEVDDIWSYGCNLAKLGDKKLFAGIVREFKEDNPGAPHCDVMAWG
                     FLEYYKDKPNIINQIAANVYLKTSASGGEIVLWDEWPTQSEYIAYKTDDPASFGLDSKK
                     IAQPKLEIQPNQGDLILFNSMRIHAVKKIETGVRMTWGCLIGYSGTDKPLVIWT"
     gene            complement(12568..13965)
                     /gene="cyrK"
     CDS             complement(12568..13965)
                     /codon_start=1
                     /gene="cyrK"
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 289.1; E-value: 8.5e-88)"
                     /gene_kind="transport"
                     /note="CyrK"
                     /product="multidrug exporter MatE"
                     /protein_id="ABX60156.1"
                     /transl_table=11
                     /translation="MSLTFPSQYDFIPRYFRLAFTNVLSNIIVPLSNLVSIMFLGHLSE
                     IHYLAGVALAGNLLNFLYFVLSFLRMGTTALTAQAVGRDDREGVLLAGLLNGLIALVLG
                     VAIILLQYPLGVLGFSILDVGPEVKSSAQAYFNTQSWGAPAILLNFVLLGWFLGREKNG
                     LVVLLSVVGNAANIALDYLFIIHLDWSSMGAGVASAASQYLTLLVGLFFVCKEIPWQEV
                     KELAGKIWDIKAIRSTLTLNGNIFVSNLVCMFTNLTFNYEGAQMGTIIYAQNALLLQIW
                     ALSIYIVEGLGFCTETLAGNFKGKGATEQLAPLAKVSVGMALLVSLVFGGACWLFPDDV
                     FGLLTNHAEIIENIDIFIPWLVLVLVCNSVCCILCGYFLGLAQGHTLRNVNLIAFGVGF
                     LPADVAAVKFESNHILWLAFFLFNAIGMLMFGAQLPRTFESVVENDSVSIPALEASRAL
                     TQMETLH"
     gene            14037..14786
                     /gene="cyrL"
     CDS             14037..14786
                     /codon_start=1
                     /gene="cyrL"
                     /note="CyrL"
                     /product="transposase"
                     /protein_id="ABX60157.1"
                     /transl_table=11
                     /translation="MLNLDRILNQERLLREMTGLNRQAFNELLSQFADTYERTVFNSLA
                     NRKRAPGGGRKPTLRSIEEKLFYILLYCKCYPTFDLLSVLFNFDRSCAHDWVHRLLSVL
                     ETTLGEKQVLPARKLRSMEEFTKRFPDVKEVIVDGTERPVQRPQNRERQKEYYSGKKKR
                     HTCKQITVSTREKRVIIRTETRAGKVHDKRLLHESEIVQYIPDEVAIEGDLGFHGLEKE
                     FVNVHLPHKKPKGIEARRHGGGMGQFL"
     gene            14886..16316
                     /gene="cyrH"
     CDS             14886..16316
                     /codon_start=1
                     /gene="cyrH"
                     /note="CyrH; putative uracil ring formation"
                     /product="aminohydrolase"
                     /protein_id="ABX60158.1"
                     /transl_table=11
                     /translation="MNLITTKKQVDTLVIHAHLFTMQGNGVGYIADGALAVEGSRIVAV
                     DSTEALLSHFEGRKVIESANCAVLPGLINAHVDTSLVLMRGAAQDVTNWLMDATMPYFA
                     HMTPVASMAATRLRVVEELKAGTTTFCDNKIISPLWGEFFDEIGVRASLAPMFDALPLE
                     MPPLQDGELYPFDIKAGRRAMAEAVDFACGWNGAAEGRITTMLGMYSPDMMPLEMLRAA
                     KEIAQREGLMLHFHVAQGDRETEQIVKRYGKRPIAFLAEIGYLDEQLLAVHLTDATDEE
                     VIQVAKSGAGMVLCSGMIGTIDGIVPPAHVFRQAGGPVALGSSYNNIFHEMKLTALFNK
                     IKYHDPTIMPAWEVLRMATIEGARAIGLDHKIGSLEVGKEADLILIDLSTPNLSPTLLN
                     PIRNLVPNFVYAASGHEVKSVMVAGKLLLEDYQVLTVDESAIIAEAQLQAQQISQCVAS
                     DPIHKKMVLMAAMARGQL"
     gene            16893..17672
                     /gene="cyrJ"
     CDS             16893..17672
                     /codon_start=1
                     /gene="cyrJ"
                     /note="CyrJ"
                     /product="putative sulfotransferase"
                     /protein_id="ABX60159.1"
                     /transl_table=11
                     /translation="MQEKRIAMWSVPRSLGTVLLQAWSSRPDTVVFDELLSFPYLFIKG
                     KDMGFTWTDLDSSQMPHADWRSVIDLLKAPLPEGKSIIDLLKAPLPEGKSICYQKHQAY
                     HLIEETMGIEWILPFSNCFLIRQPKEMLLSFRKIVPHFTFEETGWIELKRLFDYVHQTS
                     GVIPPVIDAHDLLNDPRRMLSKLCQVVGVEFTETMLSWPPMEVELNEKLAPWYSTVASS
                     THFHSYQNKNESLPLYLVDICKRCDEIYQELYQFRLY"
     gene            18113..19288
                     /gene="cyrA"
     CDS             18113..19288
                     /codon_start=1
                     /gene="cyrA"
                     /note="CyrA"
                     /product="amidinotransferase"
                     /protein_id="ABX60160.1"
                     /transl_table=11
                     /translation="MQTRIVNSWNEWDELKEMVVGIADGAYFEPTEPGNRPALRDKNIA
                     KMFSFPRGPKKQEVTEKANEELNGLVALLESQGVTVRRPEKHNFGLSVKTPFFEVENQY
                     CAVCPRDVMITFGNEILEATMSRRSRFFEYLPYRKLVYEYWHKDPDMIWNAAPKPTMQN
                     AMYREDFWECPMEDRFESMHDFEFCVTQDEVIFDAADCSRFGRDIFVQESMTTNRAGIR
                     WLKRHLEPRRFRVHDIHFPLDIFPSHIDCTFVPLAPGVVLVNPDRPIKEGEEKLFMDNG
                     WQFIEAPLPTSTDDEMPMFCQSSKWLAMNVLSISPKKVICEEQEHPLHELLDKHGFEVY
                     PIPFRNVFEFGGSLHCATWDIHRTGTCEDYFPKLNYTPVTASTNGVSRFII"
     gene            19303..28056
                     /gene="cyrB"
     CDS             19303..28056
                     /NRPS_PKS="Domain: AMP-binding (28-469). E-value: 2.6e-99.
                     Score: 324.4. Matches aSDomain:
                     nrpspksdomains_cyrB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (582-649). E-value: 6.9e-19. Score:
                     59.7. Matches aSDomain: nrpspksdomains_cyrB_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (676-1110). E-value:
                     4.9e-159. Score: 521.6. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1210-1512). E-value: 1.6e-111.
                     Score: 364.3. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (1618-1835). E-value: 1.2e-35.
                     Score: 114.8. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_DH2.1"
                     /NRPS_PKS="Domain: cMT (2076-2272). E-value: 3.1e-99.
                     Score: 324.0. Matches aSDomain: nrpspksdomains_cyrB_cMT.1"
                     /NRPS_PKS="Domain: PKS_KR (2520-2697). E-value: 4.9e-67.
                     Score: 217.2. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2795-2881). E-value: 8e-23.
                     Score: 72.5. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_PP.1"
                     /codon_start=1
                     /gene="cyrB"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     332.8; E-value: 4.9e-101)"
                     /gene_kind="biosynthetic"
                     /note="CyrB"
                     /product="mixed NRPS/PKS"
                     /protein_id="ABX60161.1"
                     /sec_met_domain="AMP-binding (E-value: 4.1e-110, bitscore:
                     358.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.4e-13, bitscore:
                     39.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 4e-112, bitscore: 364.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.9e-170, bitscore:
                     557.1, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.1e-60, bitscore:
                     193.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRESPQILFDGNGTQSEFPDSCIHHLFEDQAAKRPDAIALIDG
                     EQSLTYGELNVRANHLAQHLLSLGCQPDDLLAICIERSAELFIGLLGILKAGCAYVPLD
                     VGYPGDRIEYMLRDSDARILLTSTDVAKKLALTIPALQECQTVYLDQEIFEYDFHFLAI
                     AKLLHNQYLRLLHFYFYTLIQQCQATSVSQGIQTQVLPNNLAYCIYTSGSTGNPKGILM
                     EHRSLVNMLWWHQQTRPSVQGVRTLQFCAVSFDFSCHEIFSTLCLGGILVLVPEAVRQN
                     PFALAEFISQQKIEKLFLPVIALLQLAEAVNGNKSTSLALCEVITTGEQMQITPAVANL
                     FQKTGAMLHNHYGATEFQDATTHTLKGNPEGWPTLVPVGRPLHNVQVYILDEAQQPVPL
                     GGEGEFCIGGIGLARGYHNLPDLTNEKFIPNPFGANENAKKLYRTGDLARYLPDGTIEH
                     LGRIDHQVKIRGFRVELGEIESVLASHQAVRECAVVAREIAGHTQLVGYIIAKDTLNLS
                     FDKLEPILRQYSEAVLPEYMIPTRFINISNMPLTPSGKLDRRALPDPKGDRPALSTPLV
                     KPRTQTEKRLAEIWGSYLAVDIVGTHDNFFDLGGTSLLLTQAHKFLCETFNINLSAVSL
                     FQYPTIQTLAQYIDCQGDTTSSDTASRHKKVRKKQSGDSNDIAIISVAGRFPGAETIEQ
                     FWHNLCNGVESITLFSDDELEQTLPELFNNPAYVKAGAVLEGVELFDATFFGYSPKEAA
                     VTDPQQRILLECAWEAFERAGYNPETYPEPVGVYAGSSLSTYLLNNIGSALGIITEQPF
                     IETDMEQFQAKIGNDRSYLATRISYKLNLKGPSVNVQTACSTSLVAVHMACQSLISGEC
                     QMALAGGISVVVPQKGGYLYEEGMVRSQDGHCRAFDAEAQGTIFGNGGGLVLLKRLQDA
                     LDDNDNIMAVIKATAINNDGALKMGYTAPSVDGQADVISEAIAIADIDASTIGYVEAHG
                     TATQLGDPIEVAGLARAFQRSTDSVLGKQQCAIGSVKTNIGHLDEAAGIAGLIKAALAL
                     QYGQIPPSLHYANPNPRIDFDATPFFVNTELREWSRNGYPRRAGVSSFGVGGTNSHIVL
                     EESPVKQPTLFSSLPERSHHLLTLSAHTQEALHELVQRYIQHNETHLDINLGDLCFTAN
                     TGRKHFEHRLAVVAESIPGLQAQLETAQTAISAQKKNAPPTIAFLFTGQGSQYINMGRT
                     LYDTESTFRAALDRCETILQNLGIESILSVIFGSSEHGLSLDDTAYTQPALFAIEYALY
                     QLWKSWGIQPSVVIGHSVGEYVSACVAGVFSLEDGLKLIAERGRLIQALPRDGSMVSVM
                     ASEKRIADIILPYGGQVGIAAINGPQSVVISGQQQAIDAICAILETEGIKSKKLNVSHA
                     FHSPLVEAMLDSFLQVAQEVTYSQPQIKLISNVTGTLASHESCPDELPITTAEYWVRHV
                     RQPVRFAAGMESLEGQGVNVFIEIGPKPVLLGMGRDCLPEQEGLWLPSLRPKQDDWQQV
                     LSSLRDLYLAGVTVDWSSFDQGYARRRVPLPTYPWQRERHWVEPIIRQRQSVLQATNTT
                     KLTRNASVAQHPLLGQRLHLSRTQEIYFQTFIHSDFPIWVADHKVFGNVIIPGVAYFEM
                     ALAAGKALKPDSIFWLEDVSIAQALIIPDEGQTVQIVLSPQEESAYFFEILSLEKENSW
                     VLHASGKLVAQEQVLETEPIDLIALQAHCSEEVSVDVLYQEEMARRLDMGPMMRGVKQL
                     WRYPLSFAKSHDAIALAKVSLPEILLHESNAYQFHPVILDAGLQMITVSYPEANQGQTY
                     VPVGIEGLQVYGRPSSELWCRAQYRPPLDTDQRQGIDLLPKKLIADLHLFDTQGRVVAI
                     MFGVQSVLVGREAMLRSQDTWRNWLYQVLWKPQACFGLLPNYLPTPDKIRKRLETKLAT
                     LIIEANLATYAIAYTQLERLSLAYVVAAFRQMGWLFQPGERFSTAQKVSALGIVDQHRQ
                     LFARLLDILAEADILRSENLMTIWEVISYPETIDIQVLLDDLEAKEAEAEVTLVSRCSA
                     KLAEVLQGKCDPIQLLFPAGDTTTLSKLYREAPVLGVTNTLVQEALLSALEQLPPERGW
                     RILEIGAGTGGTTAYLLPHLPGDQTKYVFTDISAFFLAKAEERFKDYPFVRYQVLDIEQ
                     APQAQGFEPQIYDLIVAADVLHATSDLRQTLVHIRQLLAPGGMLILMEDSEPARWADLT
                     FGLTEGWWKFTDHDLRPNHPLLSPEQWQILLSEMGFSQTTALWPKIDSPHKLPREAVIV
                     ARNEPAIRKPRRWLILADEEIGGLLAKQLREEGEDCILLLPGEKYTERDSQTFTINPGD
                     IEEWQQLLNRVPNIQEIVHCWSMVSTDLDRATIFSCSSTLHLVQALANYPKNPRLSLVT
                     LGAQAVNEHHVQNVVGAALWGMGKVIALEHPELQVAQMDLDPNGKVKAQVEVLRDELLA
                     RKDPASAMSVPDLQTRPHEKQIAFREQTRYVARLSPLDRPNPGEKGTQEALTFRDDGSY
                     LIAGGLGGLGLVVARFLVTNGAKYLVLVGRRGAREEQQAQLSELEQLGASVKVLQADIA
                     DAEQLAQALSAVTYPPLRGVIHAAGTLNDGILQQQSWQAFKEVMNPKVAGAWNLHILTK
                     NQPLDFFVLFSSATSLLGNAGQANHAAANAFLDGLASYRRHLGLPSLSINWGTWSEVGI
                     AARLELDKLSSKQGEGTITLGQGLQILEQLLKDENGVYQVGVMPINWTQFLARQLTPQP
                     FFSDAMKSIDTSVGKLTLQERDSCPQGYGHNIREQLENAPPKEGLTLLQAHVREQVSQV
                     LGIDTKTLLAEQDVGFFTLGMDSLTSVELRNRLQASLGCSLSSTLAFDYPTQQALVNYL
                     ANELLGTPEQLQEPESDEEDQISSMDDIVQLLSAKLEMEI"
     aSDomain        19387..20709
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_AMP-binding.1"
                     /evalue="2.60E-99"
                     /label="cyrB_AMP-binding.1"
                     /locus_tag="cyrB"
                     /protein_end="469"
                     /protein_start="28"
                     /score="324.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEDQAAKRPDAIALIDGEQSLTYGELNVRANHLAQHLLSLGCQPD
                     DLLAICIERSAELFIGLLGILKAGCAYVPLDVGYPGDRIEYMLRDSDARILLTSTDVAK
                     KLALTIPALQECQTVYLDQEIFEYDFHFLAIAKLLHNQYLRLLHFYFYTLIQQCQATSV
                     SQGIQTQVLPNNLAYCIYTSGSTGNPKGILMEHRSLVNMLWWHQQTRPSVQGVRTLQFC
                     AVSFDFSCHEIFSTLCLGGILVLVPEAVRQNPFALAEFISQQKIEKLFLPVIALLQLAE
                     AVNGNKSTSLALCEVITTGEQMQITPAVANLFQKTGAMLHNHYGATEFQDATTHTLKGN
                     PEGWPTLVPVGRPLHNVQVYILDEAQQPVPLGGEGEFCIGGIGLARGYHNLPDLTNEKF
                     IPNPFGANENAKKLYRTGDLARYLPDGTIEHLGRIDHQVKIR"
     aSModule        19387..21249
                     /complete
                     /domains="nrpspksdomains_cyrB_AMP-binding.1"
                     /domains="nrpspksdomains_cyrB_PCP.1"
                     /locus_tags="cyrB"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       19573..19614
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0001"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="cyrB"
                     /protein_end="104"
                     /protein_start="90"
                     /score="18.6"
                     /tool="antismash"
                     /translation="LGILKAGCAYVPLD"
     CDS_motif       19915..19974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0002"
                     /evalue="5.90E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="cyrB"
                     /protein_end="224"
                     /protein_start="204"
                     /score="28.0"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGNPKGILMEH"
     CDS_motif       20494..20583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0003"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="cyrB"
                     /protein_end="427"
                     /protein_start="397"
                     /score="40.0"
                     /tool="antismash"
                     /translation="PLGGEGEFCIGGIGLARGYHNLPDLTNEKF"
     CDS_motif       20674..20739
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0004"
                     /evalue="9.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="cyrB"
                     /protein_end="479"
                     /protein_start="457"
                     /score="36.8"
                     /tool="antismash"
                     /translation="HLGRIDHQVKIRGFRVELGEIE"
     aSDomain        21049..21249
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PCP.1"
                     /evalue="6.90E-19"
                     /label="cyrB_PCP.1"
                     /locus_tag="cyrB"
                     /protein_end="649"
                     /protein_start="582"
                     /score="59.7"
                     /tool="antismash"
                     /translation="EKRLAEIWGSYLAVDIVGTHDNFFDLGGTSLLLTQAHKFLCETFN
                     INLSAVSLFQYPTIQTLAQYID"
     aSDomain        21331..22632
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="4.90E-159"
                     /label="cyrB_PKS_KS.1"
                     /locus_tag="cyrB"
                     /protein_end="1110"
                     /protein_start="676"
                     /score="521.6"
                     /tool="antismash"
                     /translation="IAIISVAGRFPGAETIEQFWHNLCNGVESITLFSDDELEQTLPEL
                     FNNPAYVKAGAVLEGVELFDATFFGYSPKEAAVTDPQQRILLECAWEAFERAGYNPETY
                     PEPVGVYAGSSLSTYLLNNIGSALGIITEQPFIETDMEQFQAKIGNDRSYLATRISYKL
                     NLKGPSVNVQTACSTSLVAVHMACQSLISGECQMALAGGISVVVPQKGGYLYEEGMVRS
                     QDGHCRAFDAEAQGTIFGNGGGLVLLKRLQDALDDNDNIMAVIKATAINNDGALKMGYT
                     APSVDGQADVISEAIAIADIDASTIGYVEAHGTATQLGDPIEVAGLARAFQRSTDSVLG
                     KQQCAIGSVKTNIGHLDEAAGIAGLIKAALALQYGQIPPSLHYANPNPRIDFDATPFFV
                     NTELREWSRNGYPRRAGVSSFGVGGTNSHIVLEES"
     aSModule        21331..27945
                     /complete
                     /domains="nrpspksdomains_cyrB_PKS_KS.1"
                     /domains="nrpspksdomains_cyrB_PKS_AT.1"
                     /domains="nrpspksdomains_cyrB_PKS_DH2.1"
                     /domains="nrpspksdomains_cyrB_cMT.1"
                     /domains="nrpspksdomains_cyrB_PKS_KR.1"
                     /domains="nrpspksdomains_cyrB_PKS_PP.1"
                     /locus_tags="cyrB"
                     /monomer_pairings="mal -> Me-ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       21829..21876
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0005"
                     /evalue="1.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrB"
                     /protein_end="858"
                     /protein_start="842"
                     /score="17.0"
                     /tool="antismash"
                     /translation="GPSVNVQTACSTSLVA"
     CDS_motif       22252..22299
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0006"
                     /evalue="6.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrB"
                     /protein_end="999"
                     /protein_start="983"
                     /score="12.0"
                     /tool="antismash"
                     /translation="YVEAHGTATQLGDPIE"
     CDS_motif       22369..22413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0007"
                     /evalue="3.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrB"
                     /protein_end="1037"
                     /protein_start="1022"
                     /score="10.1"
                     /tool="antismash"
                     /translation="GSVKTNIGHLDEAAG"
     aSDomain        22933..23838
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_AT.1"
                     /evalue="1.60E-111"
                     /label="cyrB_PKS_AT.1"
                     /locus_tag="cyrB"
                     /protein_end="1512"
                     /protein_start="1210"
                     /score="364.3"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYINMGRTLYDTESTFRAALDRCETILQNLGIESILSV
                     IFGSSEHGLSLDDTAYTQPALFAIEYALYQLWKSWGIQPSVVIGHSVGEYVSACVAGVF
                     SLEDGLKLIAERGRLIQALPRDGSMVSVMASEKRIADIILPYGGQVGIAAINGPQSVVI
                     SGQQQAIDAICAILETEGIKSKKLNVSHAFHSPLVEAMLDSFLQVAQEVTYSQPQIKLI
                     SNVTGTLASHESCPDELPITTAEYWVRHVRQPVRFAAGMESLEGQGVNVFIEIGPKPVL
                     LGMGRDCLPEQEGLWLPSLRP"
     CDS_motif       22936..22983
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0008"
                     /evalue="2.80E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrB"
                     /protein_end="1227"
                     /protein_start="1211"
                     /score="19.7"
                     /tool="antismash"
                     /translation="FTGQGSQYINMGRTLY"
     CDS_motif       23107..23169
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0009"
                     /evalue="4.50E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrB"
                     /protein_end="1289"
                     /protein_start="1268"
                     /score="13.4"
                     /tool="antismash"
                     /translation="TAYTQPALFAIEYALYQLWKS"
     CDS_motif       23173..23295
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0010"
                     /evalue="1.10E-26"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrB"
                     /protein_end="1331"
                     /protein_start="1290"
                     /score="85.2"
                     /tool="antismash"
                     /translation="GIQPSVVIGHSVGEYVSACVAGVFSLEDGLKLIAERGRLIQ"
     CDS_motif       23389..23427
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0011"
                     /evalue="9.80E-05"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrB"
                     /protein_end="1375"
                     /protein_start="1362"
                     /score="15.5"
                     /tool="antismash"
                     /translation="AAINGPQSVVISG"
     CDS_motif       23668..23703
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0012"
                     /evalue="6.10E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="cyrB"
                     /protein_end="1467"
                     /protein_start="1455"
                     /score="16.3"
                     /tool="antismash"
                     /translation="YWVRHVRQPVRF"
     CDS_motif       24154..24231
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0013"
                     /evalue="1.30E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="cyrB"
                     /protein_end="1643"
                     /protein_start="1617"
                     /score="33.7"
                     /tool="antismash"
                     /translation="WVADHKVFGNVIIPGVAYFEMALAAG"
     aSDomain        24157..24807
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_DH2.1"
                     /evalue="1.20E-35"
                     /label="cyrB_PKS_DH2.1"
                     /locus_tag="cyrB"
                     /protein_end="1835"
                     /protein_start="1618"
                     /score="114.8"
                     /tool="antismash"
                     /translation="VADHKVFGNVIIPGVAYFEMALAAGKALKPDSIFWLEDVSIAQAL
                     IIPDEGQTVQIVLSPQEESAYFFEILSLEKENSWVLHASGKLVAQEQVLETEPIDLIAL
                     QAHCSEEVSVDVLYQEEMARRLDMGPMMRGVKQLWRYPLSFAKSHDAIALAKVSLPEIL
                     LHESNAYQFHPVILDAGLQMITVSYPEANQGQTYVPVGIEGLQVYGRPSSELWC"
     aSDomain        25531..26118
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_cMT.1"
                     /domain_subtype="cMT"
                     /evalue="3.10E-99"
                     /label="cyrB_cMT.1"
                     /locus_tag="cyrB"
                     /protein_end="2272"
                     /protein_start="2076"
                     /score="324.0"
                     /tool="antismash"
                     /translation="SKLYREAPVLGVTNTLVQEALLSALEQLPPERGWRILEIGAGTGG
                     TTAYLLPHLPGDQTKYVFTDISAFFLAKAEERFKDYPFVRYQVLDIEQAPQAQGFEPQI
                     YDLIVAADVLHATSDLRQTLVHIRQLLAPGGMLILMEDSEPARWADLTFGLTEGWWKFT
                     DHDLRPNHPLLSPEQWQILLSEMGFSQTTALWP"
     aSDomain        26863..27393
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_KR.1"
                     /evalue="4.90E-67"
                     /label="cyrB_PKS_KR.1"
                     /locus_tag="cyrB"
                     /protein_end="2697"
                     /protein_start="2520"
                     /score="217.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="GSYLIAGGLGGLGLVVARFLVTNGAKYLVLVGRRGAREEQQAQLS
                     ELEQLGASVKVLQADIADAEQLAQALSAVTYPPLRGVIHAAGTLNDGILQQQSWQAFKE
                     VMNPKVAGAWNLHILTKNQPLDFFVLFSSATSLLGNAGQANHAAANAFLDGLASYRRHL
                     GLPSLSINWGTWSE"
     CDS_motif       26866..26964
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0014"
                     /evalue="4.00E-14"
                     /label="PKSI-KR_m1"
                     /locus_tag="cyrB"
                     /protein_end="2554"
                     /protein_start="2521"
                     /score="45.1"
                     /tool="antismash"
                     /translation="SYLIAGGLGGLGLVVARFLVTNGAKYLVLVGRR"
     CDS_motif       27184..27213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0015"
                     /evalue="1.80E-03"
                     /label="PKSI-KR_m3"
                     /locus_tag="cyrB"
                     /protein_end="2637"
                     /protein_start="2627"
                     /score="11.7"
                     /tool="antismash"
                     /translation="PKVAGAWNLH"
     CDS_motif       27235..27345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0016"
                     /evalue="1.70E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="cyrB"
                     /protein_end="2681"
                     /protein_start="2644"
                     /score="65.6"
                     /tool="antismash"
                     /translation="LDFFVLFSSATSLLGNAGQANHAAANAFLDGLASYRR"
     aSDomain        27688..27945
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_PP.1"
                     /evalue="8.00E-23"
                     /label="cyrB_PKS_PP.1"
                     /locus_tag="cyrB"
                     /protein_end="2881"
                     /protein_start="2795"
                     /score="72.5"
                     /tool="antismash"
                     /translation="ENAPPKEGLTLLQAHVREQVSQVLGIDTKTLLAEQDVGFFTLGMD
                     SLTSVELRNRLQASLGCSLSSTLAFDYPTQQALVNYLANEL"
     gene            28061..33727
                     /gene="cyrE"
     CDS             28061..33727
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (36-450). E-value:
                     2.5e-179. Score: 588.4. Matches aSDomain:
                     nrpspksdomains_cyrE_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (548-850). E-value: 4.1e-114.
                     Score: 372.7. Matches aSDomain:
                     nrpspksdomains_cyrE_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH2 (939-1176). E-value: 5.3e-30.
                     Score: 96.3. Matches aSDomain:
                     nrpspksdomains_cyrE_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (1480-1659). E-value: 7.6e-59.
                     Score: 190.5. Matches aSDomain:
                     nrpspksdomains_cyrE_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1752-1837). E-value: 4.2e-21.
                     Score: 67.0. Matches aSDomain:
                     nrpspksdomains_cyrE_PKS_PP.1"
                     /codon_start=1
                     /gene="cyrE"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 114.8; E-value:
                     6.7e-35)"
                     /gene_kind="biosynthetic"
                     /note="CyrE"
                     /product="polyketide synthase"
                     /protein_id="ABX60162.1"
                     /sec_met_domain="PP-binding (E-value: 3e-10, bitscore:
                     30.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-114, bitscore:
                     372.7, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 3.3e-195, bitscore:
                     638.7, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 8.2e-54, bitscore:
                     172.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEKLRTYERLIKQSYHKIEALEAEVNRLKQTQCEPIAIVGMGCR
                     FPGANSPEAFWQLLCDGVDAIREIPKNRWVVDAYIDENLDRADKTSMRFGGFVEQLEKF
                     DAQFFGISPREAVSLDPQQRLLLEVSWEALENAAVIPPSATGVFVGISNLDYRETLLKQ
                     GAIGTYFASGNAHSTASGRLSYFLGLTGPCLSIDTACSSSLVAVHQSLISLRQRECDLA
                     LVGGVHRLIAPEESVSLAKAHMLSPDGRCKVFDASANGYVRAEGCGMIVLKRLSDAQAD
                     GDKILALIRGSAINQDGRTSGLTVPNGPQQADVIRQALANSGIRPEQVNYVEAHGTGTS
                     LGDPIEVGALGTIFNQRSQPLIIGSVKTNIGHLEAAAGIAGLIKVVLAMQHGEIPPNLH
                     FHQPNPRINWDKLPIRIPTERTAWPTGDRIAGISSFGFSGTNSHVVLEEAPKIEPSTLE
                     IHSKQYVFTLSAATPQALQELTQRYVTYLTEHLQESLADICFTANTGRKHFRHRFAVVA
                     ESKTQLRQQLETFAQSGEGQGKRTSLSKIAFLFTGQGSQYVGMGQELYESQPTFRQTID
                     RCDEILRSLLGKSILSILYPSQQMGLETPSQIDETAYTQPTLFSLEYALAQLWRSWGIE
                     PDVVMGHSVGEYVAACVAGVFSLEDGLKLIAERGRLMQELPPDGAMVSVMANKSRIEQA
                     IQSVSREVSIAAINGPESVVISGKREILQQITEHLVAEGIKTRQLKVSHAFHSPLMEPI
                     LGQFRRVANTITYRPPQINLVSNVTGGQVYKEIATPDYWVRHLQETVRFADGVKVLHEQ
                     NVNFMLEIGPKPTLLGMVELQSSENPFSMPMMMPSLRQNRSDWQQMLESLSQLYVHGVE
                     IDWIGFNKDYVRHKVVLPTYPWQKERYWVELDQQKHAAKNLHPLLDRCMKLPRHNETIF
                     EKEFSLETLPFLADYRIYGSVVSPGASYLSMILSIAESYANGHLNGGNSAKQTTYLLKD
                     VTFPVPLVISDEANYMVQVACSLSCAAPHNRGDETQFELFSFAENVPESSSINADFQTP
                     IIHAKGQFKLEDTAPPKVELEELQAGCPQEIDLNLFYQTFTDKGFVFGSRFRWLEQIWV
                     GDGEALARLRQPESIESFKGYVIHPGLLDACTQVPFAISSDDENRQSETTMPFALNELR
                     CYQPANGQMWWVHATEKDRYTWDVSLFDESGQVIAEFIGLEVRAAMPEGLLRADFWHNW
                     LYTVNWRSQPLQIPEVLDINKTGAETWLLFAQPEGIGADLAEYLQSQGKHCVFVVPGSE
                     YTVTEQHIGRTGHLDVTKLTKIVTINPASPHDYKYFLETLTDIRLPCEHILYLWNRYDL
                     TNTSNHRTELTVPDIVLNLCTSLTYLVQALSHMGFSPKLWLITQNSQAVGSDLANLEIE
                     QSPLWALGRSIRAEHPEFDCRCLDFDTLSNIAPLLLKEMQAIDYESQIAYRQGTRYVAR
                     LIRNQSECHAPIQTGIRPDGSYLITGGLGGLGLQVALALADAGARHLILNSRRGTVSKE
                     AQLIIDRLRQEDVRVDLIAADVSDAADSERLLVESQRKTSLRGIVHVAGVLDDGILLQQ
                     NQERFEKVMAAKVRGAWHLDQQSQTLDLDFFVAFSSVASLIEEPGQANYAAANAFLDSL
                     MYYRHIKGSNSLSINWGAWAEVGMAANLSWEQRGIAAISPKQGRHILVQLIQKLNQHTI
                     PQVAVQPTNWAEYLSHDGVNMPFYEYFTHHLRNEKEAKLRQTAGSTSEEVSLRQQLQTL
                     SEKDRDALLMEHLQKTAIRVLGLASNQKIDPYQGLMNMGLDSLMAVEFRNHLIRSLERP
                     LPATLLFNCPTLDSLHDYLVAKMFDDAPQKAEQMAQPTTLTAHSISIESKIDDNESVDD
                     IAQMLAQALNIAFE"
     aSDomain        28169..29410
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrE_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="2.50E-179"
                     /label="cyrE_PKS_KS.1"
                     /locus_tag="cyrE"
                     /protein_end="450"
                     /protein_start="36"
                     /score="588.4"
                     /tool="antismash"
                     /translation="IAIVGMGCRFPGANSPEAFWQLLCDGVDAIREIPKNRWVVDAYID
                     ENLDRADKTSMRFGGFVEQLEKFDAQFFGISPREAVSLDPQQRLLLEVSWEALENAAVI
                     PPSATGVFVGISNLDYRETLLKQGAIGTYFASGNAHSTASGRLSYFLGLTGPCLSIDTA
                     CSSSLVAVHQSLISLRQRECDLALVGGVHRLIAPEESVSLAKAHMLSPDGRCKVFDASA
                     NGYVRAEGCGMIVLKRLSDAQADGDKILALIRGSAINQDGRTSGLTVPNGPQQADVIRQ
                     ALANSGIRPEQVNYVEAHGTGTSLGDPIEVGALGTIFNQRSQPLIIGSVKTNIGHLEAA
                     AGIAGLIKVVLAMQHGEIPPNLHFHQPNPRINWDKLPIRIPTERTAWPTGDRIAGISSF
                     GFSGTNSHVVLEEAP"
     aSModule        28169..33571
                     /complete
                     /domains="nrpspksdomains_cyrE_PKS_KS.1"
                     /domains="nrpspksdomains_cyrE_PKS_AT.1"
                     /domains="nrpspksdomains_cyrE_PKS_DH2.1"
                     /domains="nrpspksdomains_cyrE_PKS_KR.1"
                     /domains="nrpspksdomains_cyrE_PKS_PP.1"
                     /locus_tags="cyrE"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       28631..28678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0001"
                     /evalue="3.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrE"
                     /protein_end="206"
                     /protein_start="190"
                     /score="19.0"
                     /tool="antismash"
                     /translation="GPCLSIDTACSSSLVA"
     CDS_motif       28820..28858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0002"
                     /evalue="2.10E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="cyrE"
                     /protein_end="266"
                     /protein_start="253"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FDASANGYVRAEG"
     CDS_motif       29051..29098
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0003"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrE"
                     /protein_end="346"
                     /protein_start="330"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YVEAHGTGTSLGDPIE"
     CDS_motif       29150..29194
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0004"
                     /evalue="3.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrE"
                     /protein_end="378"
                     /protein_start="363"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAAAG"
     aSDomain        29705..30610
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrE_PKS_AT.1"
                     /evalue="4.10E-114"
                     /label="cyrE_PKS_AT.1"
                     /locus_tag="cyrE"
                     /protein_end="850"
                     /protein_start="548"
                     /score="372.7"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYVGMGQELYESQPTFRQTIDRCDEILRSLLGKSILSI
                     LYPSQQMGLETPSQIDETAYTQPTLFSLEYALAQLWRSWGIEPDVVMGHSVGEYVAACV
                     AGVFSLEDGLKLIAERGRLMQELPPDGAMVSVMANKSRIEQAIQSVSREVSIAAINGPE
                     SVVISGKREILQQITEHLVAEGIKTRQLKVSHAFHSPLMEPILGQFRRVANTITYRPPQ
                     INLVSNVTGGQVYKEIATPDYWVRHLQETVRFADGVKVLHEQNVNFMLEIGPKPTLLGM
                     VELQSSENPFSMPMMMPSLRQ"
     CDS_motif       29708..29755
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0005"
                     /evalue="1.90E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrE"
                     /protein_end="565"
                     /protein_start="549"
                     /score="20.2"
                     /tool="antismash"
                     /translation="FTGQGSQYVGMGQELY"
     CDS_motif       29894..29953
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0006"
                     /evalue="1.30E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrE"
                     /protein_end="631"
                     /protein_start="611"
                     /score="15.0"
                     /tool="antismash"
                     /translation="AYTQPTLFSLEYALAQLWRS"
     CDS_motif       29957..30079
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0007"
                     /evalue="2.50E-30"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrE"
                     /protein_end="673"
                     /protein_start="632"
                     /score="97.0"
                     /tool="antismash"
                     /translation="GIEPDVVMGHSVGEYVAACVAGVFSLEDGLKLIAERGRLMQ"
     CDS_motif       30173..30211
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0008"
                     /evalue="1.20E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrE"
                     /protein_end="717"
                     /protein_start="704"
                     /score="15.2"
                     /tool="antismash"
                     /translation="AAINGPESVVISG"
     CDS_motif       30431..30466
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0009"
                     /evalue="1.20E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="cyrE"
                     /protein_end="802"
                     /protein_start="790"
                     /score="12.4"
                     /tool="antismash"
                     /translation="YWVRHLQETVRF"
     aSDomain        30878..31588
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrE_PKS_DH2.1"
                     /evalue="5.30E-30"
                     /label="cyrE_PKS_DH2.1"
                     /locus_tag="cyrE"
                     /protein_end="1176"
                     /protein_start="939"
                     /score="96.3"
                     /tool="antismash"
                     /translation="PFLADYRIYGSVVSPGASYLSMILSIAESYANGHLNGGNSAKQTT
                     YLLKDVTFPVPLVISDEANYMVQVACSLSCAAPHNRGDETQFELFSFAENVPESSSINA
                     DFQTPIIHAKGQFKLEDTAPPKVELEELQAGCPQEIDLNLFYQTFTDKGFVFGSRFRWL
                     EQIWVGDGEALARLRQPESIESFKGYVIHPGLLDACTQVPFAISSDDENRQSETTMPFA
                     LNELRCYQPANGQMW"
     CDS_motif       30881..30952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0010"
                     /evalue="1.10E-05"
                     /label="PKSI-DH_m2"
                     /locus_tag="cyrE"
                     /protein_end="964"
                     /protein_start="940"
                     /score="18.1"
                     /tool="antismash"
                     /translation="FLADYRIYGSVVSPGASYLSMILS"
     CDS_motif       31070..31108
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0011"
                     /evalue="1.30E+01"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrE"
                     /protein_end="1016"
                     /protein_start="1003"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="YMVQVACSLSCAA"
     aSDomain        32501..33037
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrE_PKS_KR.1"
                     /evalue="7.60E-59"
                     /label="cyrE_PKS_KR.1"
                     /locus_tag="cyrE"
                     /protein_end="1659"
                     /protein_start="1480"
                     /score="190.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GSYLITGGLGGLGLQVALALADAGARHLILNSRRGTVSKEAQLII
                     DRLRQEDVRVDLIAADVSDAADSERLLVESQRKTSLRGIVHVAGVLDDGILLQQNQERF
                     EKVMAAKVRGAWHLDQQSQTLDLDFFVAFSSVASLIEEPGQANYAAANAFLDSLMYYRH
                     IKGSNSLSINWGAWAE"
     CDS_motif       32504..32602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0012"
                     /evalue="2.30E-15"
                     /label="PKSI-KR_m1"
                     /locus_tag="cyrE"
                     /protein_end="1514"
                     /protein_start="1481"
                     /score="49.1"
                     /tool="antismash"
                     /translation="SYLITGGLGGLGLQVALALADAGARHLILNSRR"
     CDS_motif       32879..32989
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrE_0013"
                     /evalue="3.90E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="cyrE"
                     /protein_end="1643"
                     /protein_start="1606"
                     /score="64.4"
                     /tool="antismash"
                     /translation="LDFFVAFSSVASLIEEPGQANYAAANAFLDSLMYYRH"
     aSDomain        33317..33571
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrE_PKS_PP.1"
                     /evalue="4.20E-21"
                     /label="cyrE_PKS_PP.1"
                     /locus_tag="cyrE"
                     /protein_end="1837"
                     /protein_start="1752"
                     /score="67.0"
                     /tool="antismash"
                     /translation="LQTLSEKDRDALLMEHLQKTAIRVLGLASNQKIDPYQGLMNMGLD
                     SLMAVEFRNHLIRSLERPLPATLLFNCPTLDSLHDYLVAK"
     gene            34299..39302
                     /gene="cyrC"
     CDS             34299..39302
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (34-462). E-value:
                     4.7e-183. Score: 600.7. Matches aSDomain:
                     nrpspksdomains_cyrC_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (568-879). E-value: 4.3e-110.
                     Score: 359.6. Matches aSDomain:
                     nrpspksdomains_cyrC_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1253-1430). E-value: 1.5e-69.
                     Score: 225.4. Matches aSDomain:
                     nrpspksdomains_cyrC_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1525-1608). E-value: 1.7e-23.
                     Score: 74.6. Matches aSDomain:
                     nrpspksdomains_cyrC_PKS_PP.1"
                     /codon_start=1
                     /gene="cyrC"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093:Beta-ketoacyl synthase (Score: 114.9; E-value:
                     6.1e-35)"
                     /gene_kind="biosynthetic"
                     /note="CyrC"
                     /product="polyketide synthase"
                     /protein_id="ABX60163.1"
                     /sec_met_domain="PP-binding (E-value: 1.4e-12, bitscore:
                     37.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.1e-110, bitscore:
                     359.6, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.3e-197, bitscore:
                     645.9, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.5e-65, bitscore:
                     210.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPNYGILMKNALNEINSLRSQLAAVEAQKNESIAIVGMSCRFP
                     GGATTPERFWVLLREGISAITEIPADRWDVDKYYDADPTSSGKMHTRYGGFLNEVDTFE
                     PSFFNIAAREAVSMDPQQRLLLEVSWEALESGNIVPATLFDSSTGVFIGIGGSNYKSLM
                     IENRSRIGKTDLYELSGTDVSVAAGRISYVLGLMGPSFVIDTACSSSLVSVHQACQSLR
                     QRECDLALAGGVGLLIDPDEMIGLSQGGMLAPDGSCKTFDANANGYVRGEGCGMIVLKR
                     LSDATADGDNILAIIRGSMVNHDGHSSGLTAPRGPAQVSVIKQALDRAGIAPDAVSYLE
                     AHGTGTPLGDPIEMDSLNEVFGRRTEPLWVGSVKTNIGHLEAASGIAGLIKVVLMLKNK
                     QIPPHLHFKTPNPYIDWKNLPVEIPTTLHAWDDKTLKDRKRIAGVSSFSFSGTNAHIVL
                     SEAPSSELISNHAAVERPWHLLTLSAKNEEALANLVGLYQSFISTTDASLADICYTANT
                     ARTHFSHRLALSATSHIQIEALLAAYKEGSVSLSINQGCVLSNSRAPKVAFLFTGQGSQ
                     YVQMAGELYETQPTFRNCLDRCAEILQSIFSSRNSPWGNPLLSVLYPNHESKEIDQTAY
                     TQPALFAVEYALAQMWRSWGIEPDIVMGHSIGEYVAACVAGIFSLEDGLKLAAERGRLM
                     QALPQNGEMVAISASLEEVKPAIQSDQRVVIAAVNGPRSVVISGDRQAVQVFTNTLEDQ
                     GIRCKRLSVSHAFHSPLMKPMEQEFAQVAREINYSPPKIALVSNLTGDLISPESSLEEG
                     VIASPGYWVNHLCNPVLFADGIATMQAQDVQVFLEVGPKPTLSGLVQQYFDEVAHSDRP
                     VTIPTLRPKQPNWQTLLESLGQLYALGVQVNWAGFDRDYTRRKVSLPTYAWKRQRYWLE
                     KQSAPRLETTQVRPATAIVEHLEQGNVPKIVDLLAATDVLSGEARKLLPSIIELLVAKH
                     REEATQKPICDWLYEVVWQPQLLTLSTLPAVETEGRQWLIFADASGHGEALAAQLRQQG
                     DIITLVYAGLKYHSANNKQNTGGDIPYFQIDPIQREDYERLFAALPPLYGIVHLWSLDI
                     LSLDKVSNLIENVQLGSGTLLNLIQTVLQLETPTPSLWLVTKNAQAVRKNDSLVGVLQS
                     PLWGMGKVIALEHPELNCVSIDLDGEGLPDEQAKFLAAELRAASEFRHTTIPHESQVAW
                     RNRTRYVSRFKGYQKHPATSSKMPIRPDATYLITGGFGGLGLLVARWMVEQGATHLFLM
                     GRSQPKPAAQKQLQEIAALGATVTVVQADVGIRSQVANVLAQIDKAYPLAGIIHTAGVL
                     DDGILLQQNWARFSKVFAPKLEGAWHLHTLTEEMPLDFFICFSSTAGLLGSGGQANYAA
                     ANAFLDAFAHHRRIQGLPALSINWDAWSQVGMTVRLQQASSQSTTVGQDISTLEISPEQ
                     GLQIFAYLLQQPSAQIAAISTDGLRKMYDTSSAFFALLDLDRSSSTTQEQSTLSHEVGL
                     TLLEQLQQARPKEREKMLLRHLQTQVAAVLRSPELPAVHQPFTDLGMDSLMSLELMRRL
                     EESLGIQMPATLAFDYPMVDRLAKFILTQICINSEPDTSAVLTPDGNGEEKDSNKDRST
                     STSVDSNITSMAEDLFALESLLNKIKRDQ"
     aSDomain        34401..35684
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrC_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="4.70E-183"
                     /label="cyrC_PKS_KS.1"
                     /locus_tag="cyrC"
                     /protein_end="462"
                     /protein_start="34"
                     /score="600.7"
                     /tool="antismash"
                     /translation="IAIVGMSCRFPGGATTPERFWVLLREGISAITEIPADRWDVDKYY
                     DADPTSSGKMHTRYGGFLNEVDTFEPSFFNIAAREAVSMDPQQRLLLEVSWEALESGNI
                     VPATLFDSSTGVFIGIGGSNYKSLMIENRSRIGKTDLYELSGTDVSVAAGRISYVLGLM
                     GPSFVIDTACSSSLVSVHQACQSLRQRECDLALAGGVGLLIDPDEMIGLSQGGMLAPDG
                     SCKTFDANANGYVRGEGCGMIVLKRLSDATADGDNILAIIRGSMVNHDGHSSGLTAPRG
                     PAQVSVIKQALDRAGIAPDAVSYLEAHGTGTPLGDPIEMDSLNEVFGRRTEPLWVGSVK
                     TNIGHLEAASGIAGLIKVVLMLKNKQIPPHLHFKTPNPYIDWKNLPVEIPTTLHAWDDK
                     TLKDRKRIAGVSSFSFSGTNAHIVLSEAP"
     aSModule        34401..39122
                     /complete
                     /domains="nrpspksdomains_cyrC_PKS_KS.1"
                     /domains="nrpspksdomains_cyrC_PKS_AT.1"
                     /domains="nrpspksdomains_cyrC_PKS_KR.1"
                     /domains="nrpspksdomains_cyrC_PKS_PP.1"
                     /locus_tags="cyrC"
                     /monomer_pairings="mal -> ohmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       34890..34937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0001"
                     /evalue="2.70E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrC"
                     /protein_end="213"
                     /protein_start="197"
                     /score="19.3"
                     /tool="antismash"
                     /translation="GPSFVIDTACSSSLVS"
     CDS_motif       35079..35117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0002"
                     /evalue="7.60E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="cyrC"
                     /protein_end="273"
                     /protein_start="260"
                     /score="15.6"
                     /tool="antismash"
                     /translation="FDANANGYVRGEG"
     CDS_motif       35310..35357
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0003"
                     /evalue="3.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrC"
                     /protein_end="353"
                     /protein_start="337"
                     /score="12.8"
                     /tool="antismash"
                     /translation="YLEAHGTGTPLGDPIE"
     CDS_motif       35409..35453
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0004"
                     /evalue="3.30E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrC"
                     /protein_end="385"
                     /protein_start="370"
                     /score="12.9"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEAASG"
     aSDomain        36003..36935
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrC_PKS_AT.1"
                     /evalue="4.30E-110"
                     /label="cyrC_PKS_AT.1"
                     /locus_tag="cyrC"
                     /protein_end="879"
                     /protein_start="568"
                     /score="359.6"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYVQMAGELYETQPTFRNCLDRCAEILQSIFSSRNSPW
                     GNPLLSVLYPNHESKEIDQTAYTQPALFAVEYALAQMWRSWGIEPDIVMGHSIGEYVAA
                     CVAGIFSLEDGLKLAAERGRLMQALPQNGEMVAISASLEEVKPAIQSDQRVVIAAVNGP
                     RSVVISGDRQAVQVFTNTLEDQGIRCKRLSVSHAFHSPLMKPMEQEFAQVAREINYSPP
                     KIALVSNLTGDLISPESSLEEGVIASPGYWVNHLCNPVLFADGIATMQAQDVQVFLEVG
                     PKPTLSGLVQQYFDEVAHSDRPVTIPTLRP"
     CDS_motif       36006..36053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0005"
                     /evalue="2.10E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrC"
                     /protein_end="585"
                     /protein_start="569"
                     /score="17.1"
                     /tool="antismash"
                     /translation="FTGQGSQYVQMAGELY"
     CDS_motif       36198..36257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0006"
                     /evalue="7.20E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrC"
                     /protein_end="653"
                     /protein_start="633"
                     /score="18.9"
                     /tool="antismash"
                     /translation="AYTQPALFAVEYALAQMWRS"
     CDS_motif       36261..36383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0007"
                     /evalue="7.80E-29"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrC"
                     /protein_end="695"
                     /protein_start="654"
                     /score="92.2"
                     /tool="antismash"
                     /translation="GIEPDIVMGHSIGEYVAACVAGIFSLEDGLKLAAERGRLMQ"
     CDS_motif       36474..36512
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0008"
                     /evalue="1.40E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrC"
                     /protein_end="738"
                     /protein_start="725"
                     /score="15.0"
                     /tool="antismash"
                     /translation="AAVNGPRSVVISG"
     CDS_motif       36753..36788
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0009"
                     /evalue="8.30E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="cyrC"
                     /protein_end="830"
                     /protein_start="818"
                     /score="12.9"
                     /tool="antismash"
                     /translation="YWVNHLCNPVLF"
     aSDomain        38058..38588
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrC_PKS_KR.1"
                     /evalue="1.50E-69"
                     /label="cyrC_PKS_KR.1"
                     /locus_tag="cyrC"
                     /protein_end="1430"
                     /protein_start="1253"
                     /score="225.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="ATYLITGGFGGLGLLVARWMVEQGATHLFLMGRSQPKPAAQKQLQ
                     EIAALGATVTVVQADVGIRSQVANVLAQIDKAYPLAGIIHTAGVLDDGILLQQNWARFS
                     KVFAPKLEGAWHLHTLTEEMPLDFFICFSSTAGLLGSGGQANYAAANAFLDAFAHHRRI
                     QGLPALSINWDAWS"
     CDS_motif       38061..38159
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0010"
                     /evalue="8.30E-18"
                     /label="PKSI-KR_m1"
                     /locus_tag="cyrC"
                     /protein_end="1287"
                     /protein_start="1254"
                     /score="56.9"
                     /tool="antismash"
                     /translation="TYLITGGFGGLGLLVARWMVEQGATHLFLMGRS"
     CDS_motif       38433..38543
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0011"
                     /evalue="6.50E-23"
                     /label="PKSI-KR_m4"
                     /locus_tag="cyrC"
                     /protein_end="1415"
                     /protein_start="1378"
                     /score="73.4"
                     /tool="antismash"
                     /translation="LDFFICFSSTAGLLGSGGQANYAAANAFLDAFAHHRR"
     aSDomain        38874..39122
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrC_PKS_PP.1"
                     /evalue="1.70E-23"
                     /label="cyrC_PKS_PP.1"
                     /locus_tag="cyrC"
                     /protein_end="1608"
                     /protein_start="1525"
                     /score="74.6"
                     /tool="antismash"
                     /translation="LQQARPKEREKMLLRHLQTQVAAVLRSPELPAVHQPFTDLGMDSL
                     MSLELMRRLEESLGIQMPATLAFDYPMVDRLAKFILTQ"
     misc_feature    complement(39366..39683)
                     /gene="cyrM"
                     /note="similar to transposase; partial transposase"
     gene            complement(39366..39683)
                     /gene="cyrM"
     gene            complement(39793..40392)
                     /gene="cyrN"
     CDS             complement(39793..40392)
                     /codon_start=1
                     /gene="cyrN"
                     /note="CyrN"
                     /product="adenylylsulfate kinase"
                     /protein_id="ABX60164.1"
                     /transl_table=11
                     /translation="MKSSNIQHTKHLVSPFDRCLKNGHRNGILWFTGLSGSGKTTLALE
                     LERILFQKGWYTFVLDGDNIRHGLCADLGFSAADRAENIRRIGEVAKLFADSGCLVITA
                     FISPYRKDREQIRILSGDLFHEVYIATPMEICEQRDPKGLYAKARRGEIESFTGISAPY
                     EPPRTPDLLVETSELSIEASLQQLLEYVGKKFTFTQ"
     gene            40501..42048
                     /gene="cyrO"
     CDS             40501..42048
                     /codon_start=1
                     /gene="cyrO"
                     /product="CyrO"
                     /protein_id="ABX60165.1"
                     /transl_table=11
                     /translation="MPKYFNTAGPCKSEIHYMLSPTARLPDLKALIDGENYFIIHAPRQ
                     VGKTTAMIALARELTDSGKYTAVILSVEVGSVFSHNPQQAEQVILEEWKQAIKFYLPKE
                     LQPSYWPERETDSGIGKTLSEWSAQSPRPLVIFLHEIDSLTDEALILILRQLRSGFPRR
                     PRGFPHSVGLIGMRDVRDYKVKSGGSERLNTSSPFNIKAESLTLSNFTLSEVEELYLQH
                     TQATGQIFTPEAIKQAFYLTDGQPWLVNALARQATQVLVKDITQPITAEVINQAKEVLI
                     QRQDTHLDSLAERLREDRVKAIIQPMLAGSDLPDTPEDDRRFLLDLGLVKRSPLGGLTI
                     ANPIYQEVIPRVLSQGSQDSLPQIQPTWLNTDNTLNPDKLLNAFLEFWRQHGEPLLKSA
                     PYHEIAPHLVLMAFLHRVVNGGGTLEREYAVGSGRMDICLRYGKVVMGIELKVWGGKSD
                     PLTKGLTQLDKYLGGLGLDRGWLVIFDHRPGLPPMGERISMEQAISPEGRTITVIRS"
ORIGIN
        1 gtttttactg caaaagcata ttcatattat attctaatag ggttggtgga atattcaagg
       61 ggaggttaga aaatgcgatc gctcttatga atgaggttgt ctatccgaat atcaaatatt
      121 ggtggttgaa aaaagacctt atatgcggac acagattccc atgatgaaaa tatatcattg
      181 tcaagtcaat tagtcaaccc cccaatagac atctccgaaa aagaatcaaa gtgtgataaa
      241 atttgcagta cagcaggata taaaatagtt tttcctctat acttctgagt gtaggcttgc
      301 gtccgccccc gggcgcacgt ttgcggtttg ctaaggagtt aaacacggtg cgttaatatg
      361 tatcagcaac ctgagataac agctcgttga atgcttagcg gttaagtcca gtcattgctc
      421 gtagcagtcg ctcttgattc aggatgcggt ctaagttcaa cattaatgtc accctacttg
      481 tctgcttgat tattatccct tattttccaa caactctaat gaaagtacct ataacagcaa
      541 acgaagatgc agctacatta cttcagcgtg ttggactgtc cctaaaggaa gcacaccaac
      601 aacttgaggc aatgcaacgc cgagcgcacg aaccgatcgc aattgtgggg ctggggctgc
      661 ggtttccggg agctgattca ccacagacat tctggaaact acttcagaat ggtgttgata
      721 tggtcaccga aatccctagc gatcgctggg cagttgatga atactatgat ccccaacctg
      781 ggtgtccagg caaaatgtat attcgtgaag ccgcttttgt tgatgcagtg gataaattcg
      841 atgcctcgtt ttttgatatt tcgccacgtg aagcggccaa tatagatccc cagcatagaa
      901 tgttgctgga ggtagcttgg gaggcactcg aaagggctgg cattgctccc agccaattga
      961 tggatagcca aacgggggta tttgtcggga tgagcgaaaa tgactattat gctcacctag
     1021 aaaatacagg ggatcatcat aatgtctatg cggcaacggg caatagcaat tactatgctc
     1081 cggggcgttt atcctatcta ttggggcttc aaggacctaa catggtcgtt gatagtgcct
     1141 gttcctcctc cttagtggct gtacatcttg cctgtaatag tttgcggatg ggagaatgtg
     1201 atctggcact ggctggtggc gttcagctta tgttaatccc agaccctatg attgggactg
     1261 cccagttaaa tgcctttgcg accgatggtc gtagtaaaac atttgacgct gccgccgatg
     1321 gctatggacg cggcgaaggt tgtggcatga ttgtacttaa aagaataagt gacgcgatcg
     1381 tggcagacga tccaatttta gccgtaatcc ggggtagtgc agtcaatcat ggcgggcgta
     1441 gcagtggttt aactgcccct aataagctgt ctcaagaagc cttactgcgt caggcactac
     1501 aaaacgccaa ggttcagccg gaagcagtca gttatatcga agcccatggc acagggacac
     1561 aactgggcga cccgattgag gtgggagcat taacgaccgt ctttggatct tctcgttcag
     1621 aacccttgtg gattggctct gtcaaaacta atatcggaca cctagaacca gccgctggta
     1681 ttgcggggtt aataaaagtc attttatcat tacaagaaaa acagattcct cccagtctcc
     1741 attttcaaaa ccctaatccc ttcattgatt gggaatcttc gccagttcaa gtgccgacac
     1801 agtgtgtacc ctggactggg aaagagcgcg tcgctggagt tagctcgttt ggtatgagcg
     1861 gtacaaactg tcatctagtt gtcgcagaag cacctgtccg ccaaaacgaa aaatctgaaa
     1921 atgcaccgga gcgtccttgt cacattctga ccctttcagc caaaaccgaa gcggcactca
     1981 acgcattggt agcccgttac atggcatttc tcagggaagc gcccgccata tccctagctg
     2041 atctttgtta tagtgccaat gtcgggcgta atctttttgc ccatcgctta agttttatct
     2101 ccgagaacat cgcgcagtta tcagaacaat tagaacactg cccacagcag gctacaatgc
     2161 caacgcaaca taatgtgata ctagataatc aactcagccc tcaaatcgct tttctgttta
     2221 ctggacaagg ttcgcagtac atcaacatgg ggcgtgagct ttacgaaact cagcccacct
     2281 tccgtcggat tatggacgaa tgtgacgaca ttctgcatcc attgttgggt gaatcaattc
     2341 tgaacatact ctacacttcc cctagcaaac ttaatcaaac cgtttatacc caacctgccc
     2401 tttttgcttt tgaatatgcc ctagcaaaac tatggatatc atggggtatt gagcctgatg
     2461 tcgtactggg tcacagcgtg ggtgaatatg tagccgcttg tctggcgggt gtctttagtt
     2521 tagaagatgg gttaaaactc attgcatctc gtggatgttt gatgcaagcc ttaccgccgg
     2581 ggaaaatgct tagtatcaga agcaatgaga tcggagtgaa agcgctcatc gcgccttata
     2641 gtgcagaagt atcaattgca gcaatcaatg gacagcaaag cgtggtgatc tccggcaaag
     2701 ctgaaattat agataattta gcagcagagt ttgcatcgga aggcatcaaa acacacctaa
     2761 ttacagtctc ccacgctttc cactcgccaa tgatgacccc catgctgaaa gcattccgag
     2821 acgttgccag caccatcagc tataggtcac ccagtttatc actgatttct aacggtacag
     2881 ggcaattggc aacaaaggag gttgctacac ctgattattg ggtgcgtcat gtccattcta
     2941 ccgtccgttt tgccgatggt attgccacat tggcagaaca gaatactgac atcctcctag
     3001 aagtaggacc caaaccaata ttgttgggta tggcaaagca gatttatagt gaaaacggtt
     3061 cagctagtca tccgctcatg ctacccagtt tgcgtgaaga tggcaacgat tggcagcaga
     3121 tgctttctac ttgtggacaa cttgtagtta atggagtcaa gattgactgg gcgggttttg
     3181 acaaggatta ttcacgacac aaaatattgt tgcccaccta tccgtttcag agagaacgat
     3241 attggattga aagctccgtc aaaaagcccc aaaaacagga gctgcgccca atgttggata
     3301 agatgatccg gctaccatca gagaacaaag tggtgtttga aaccgagttt ggcgtgcgac
     3361 agatgcctca tatctccgat catcagatat acggtgaagt cattgtaccg ggggcagtat
     3421 tagcttcctt aatcttcaat gcagcgcagg ttttataccc agactatcag catgaattaa
     3481 ctgatattgc tttttatcag ccaattatct ttcatgacga cgatacggtg atcgtgcagg
     3541 cgattttcag ccctgataag tcacaggaga atcaaagcca tcaaacattt ccacccatga
     3601 gcttccagat tattagcttc atgccggatg gtcccttaga gaacaaaccg aaagtccatg
     3661 tcacagggtg tctgagaatg ttgcgcgatg cccaaccgcc aacactctcc ccgaccgaaa
     3721 tacgtcagcg ctgtccacat accgtaaatg gtcatgactg gtacaatagc ttagtcaaac
     3781 aaaaatttga aatgggtcct tcctttaggt gggtacagca actttggcat ggggaaaatg
     3841 aagcattgac ccgtcttcac ataccagatg tggtcggctc tgtatcagga catcaacttc
     3901 acggcatatt gctcgatggt tcactttcaa ccaccgctgt catggagtac gagtacggag
     3961 actccgcgac cagagttcct ttgtcatttg cttctctgca actgtacaaa cccgtcacgg
     4021 gaacagagtg gtggtgctac gcgaggaaga ttggggaatt caaatatgac ttccagatta
     4081 tgaatgaaat cggggaaacc ttggtgaaag caattggctt tgtacttcgt gaagcctctc
     4141 ccgaaaaatt cctcagaaca acatacgtac acaactggct tgtagacatt gaatggcaag
     4201 ctcaatcaac ttccctagtc ccttctgatg gcactatctc tggcagttgt ttggttttat
     4261 cagatcagca tggaacaggg gctgcattgg cacaaaggct agacaatgct ggagtgccag
     4321 tgaccatgat ctatgctgat ctgatactgg acaattacga attaatattc cgtactttgc
     4381 cagatttaca acaagtcgtc tatttatggg ggttggatca aaaagaggat tgtcacccca
     4441 tgaagcaagc agaggataac tgtacatcgg tgctatatct tgtgcaagca ttactcaata
     4501 cctactcaac cccgccatcc ctgcttattg tcacctgtga tgcacaagcg gtggttgaac
     4561 aagatcgagt aaatggcttc gcccaatcgt ctttgttggg acttgccaaa gttatcatgc
     4621 tagaacaccc agaattgtcc tgtgtttaca tggatgtgga agccggatat ttacagcaag
     4681 atgtggcgaa cacgatattt acacagctaa aaagaggcca tctatcaaag gacggagaag
     4741 agagtcagtt ggcttggcgc aatggacaag catacgtagc acgtcttagt caatataaac
     4801 ccaaatccga acaactggtt gagatccgca gcgatcgcag ctatttgatc actggtggac
     4861 ggggcggtgt cggcttacaa atcgcacggt ggttagtgga aaagggggct aaacatctcg
     4921 ttttgttggg gcgcagtcag accagttccg aagtcagtct ggtgttggat gagctagaat
     4981 cagccggggc gcaaatcatt gtggctcaag ctgatattag cgatgagaag gtattagcgc
     5041 agattctgac caatctaacc gtacctctgt gtggtgtaat ccacgccgca ggagtgcttg
     5101 atgatgcgag tctactccaa caaactccag ccaagctcaa aaaagttcta ttgccaaaag
     5161 cagagggggc ttggattctg cataatttga ccctggagca gcgactagac ttctttgttc
     5221 tcttttcttc tgccagttct ctattaggtg cgccagggca ggccaactat tcagcagcca
     5281 atgctttcct agatggttta gctgcctatc ggcgagggcg aggactcccc tgtttgtcta
     5341 tctgctgggg ggcatgggat caagtcggta tggctgcacg acaagggcta ctggacaagt
     5401 taccgcaaag aggtgaagag gccatcccgt tacagaaagg cttagacctc ttcggcgaat
     5461 tactgaacga gccagccgct caaattggtg tgatcccaat tcaatggact cgcttcttgg
     5521 atcatcaaaa aggtaatttg cctttttatg agaagttttc taagtctagc cggaaagcgc
     5581 agagttacga ttcgatggca gtcagtcaca cagaagatat tcagaggaaa ctgaagcaag
     5641 ctgctgtgca agatcgacca aaattattag aagtgcatct tcgctctcaa gtcgctcaac
     5701 tgttaggaat aaacgtggca gagctaccaa atgaagaagg aattggtttt gttacattag
     5761 gtcttgactc gctcacctct attgaactgc gtaacagttt acaacgcaca ttagattgtt
     5821 cattacctgt cacctttgct tttgactacc caactataga aatagcggtt aagtacctaa
     5881 cacaagttgt aattgcaccg atggaaagca cagcatcgca gcaaacagac tctttatcag
     5941 caatgttcac agatacttcg tccatcggga gaattcttga caacgaaaca gatgtgttag
     6001 acagcgaaat gcaaagtgat gaagatgaat ctttgtctac acttatacaa aaattatcaa
     6061 cacatttgga ttaggagtga tcaataatta tacattgcgg acgtgagcat acaagtaaag
     6121 gaaaaatgaa tgaacgcttt gtcagaaaat caggtaactt ctatagtcaa gaaggcattg
     6181 aacaaaatag aggagttaca agccgaactt gaccgtttaa aatacgcgca acgggaacca
     6241 atcgccatca ttggaatggg ctgtcgcttt cctggtgcag acacacctga agctttttgg
     6301 aaattattgc acaatggggt tgatgctatc caagagattc caaaaagccg ttgggatatt
     6361 gacgactatt atgatcccac accagcaaca cccggcaaaa tgtatacacg ttttggtggt
     6421 tttctcgacc aaatagcagc cttcgaccct gagttctttc gcatttctac tcgtgaggca
     6481 atcagcttag accctcaaca gagattgctt ctggaagtga gttgggaagc cttagaacgg
     6541 gctgggctga caggcaataa actgactaca caaacaggtg tctttgttgg catcagtgaa
     6601 agtgattatc gtgatttgat tatgcgtaat ggttctgacc tagatgtata ttctggttca
     6661 ggtaactgcc atagtacagc cagcgggcgt ttatcttatt atttgggact tactggaccc
     6721 aatttgtccc ttgataccgc ctgttcgtcc tctttggttt gtgtggcatt ggctgtcaag
     6781 agcctacgtc aacaggagtg tgatttggca ttggcgggtg gtgtacagat acaagtgata
     6841 ccagatggct ttatcaaagc ctgtcaatcc cgtatgttgt cgcctgatgg acggtgcaaa
     6901 acatttgatt tccaggcaga tggttatgcc cgtgctgagg ggtgtgggat ggtagttctc
     6961 aaacgcctat ccgatgcaat tgctgacaat gataatatcc tggccttgat tcgtggtgcc
     7021 gcagtcaatc atgatggcta cacgagtgga ttaaccgttc ccagtggtcc ctcacaacgg
     7081 gcggtgatcc aacaggcatt agcggatgct ggaatacacc cggatcaaat tagctatatt
     7141 gaggcacatg gcacaggtac atccttaggc gatcctattg aaatgggtgc gattgggcaa
     7201 gtctttggtc aacgctcaca gatgcttttc gtcggttcgg tcaagacgaa tattggtcat
     7261 actgaggctg ctgctggtat tgctggtctc atcaaggttg tactctcaat gcagcacggt
     7321 gaaatcccag caaacttaca cttcgaccag ccaagtcctt atattaactg ggatcaatta
     7381 ccagtcagta tcccaacaga aacaatacct tggtctacta gcgatcgctt tgcaggagtc
     7441 agtagctttg gctttagtgg cacaaactct catatcgtac tagaggcagc cccaaacata
     7501 gagcaaccta ctgatgatat taatcaaacg ccgcatattt tgaccttagc tgcaaaaaca
     7561 cccgcagccc tgcaagaact ggctcggcgt tatgcgactc agatagagac ctctcccgat
     7621 gttcctctgg cggacatttg tttcacagca cacatagggc gtaaacattt taaacatagg
     7681 tttgcggtag tcacggaatc taaagagcaa ctgcgtttgc aattggatgc atttgcacaa
     7741 tcagggggtg tggggcgaga agtcaaatcg ctaccaaaga tagcctttct ttttacaggt
     7801 caaggctcac agtatgtggg aatgggtcgt caactttacg aaaaccaacc taccttccga
     7861 aaagcactcg cccattgtga tgacatcttg cgtgctggtg catatttcga ccgatcacta
     7921 ctttcgattc tctacccaga gggaaaatca gaagccattc accaaaccgc ttatactcag
     7981 cccgcgcttt ttgctcttga gtatgcgatc gctcagttgt ggcactcctg gggtatcaaa
     8041 ccagatatcg tgatggggca tagtgtaggt gaatacgtcg ccgcttgtgt ggcgggcata
     8101 ttttctttag aggatgggct gaaactaatt gctactcgtg gtcgtctgat gcaatcccta
     8161 cctcaagacg gaacgatggt ttcttctttg gcaagtgaag ctcgtatcca ggaagctatt
     8221 acaccttacc gagatgatgt gtcaatcgca gcgataaatg ggacagaaag cgtggttatc
     8281 tctggcaaac gcacctctgt gatggcaatt gctgaacaac tcgccaccgt tggcatcaag
     8341 acacgccaac tgacggtttc ccatgccttc cattcaccac ttatgacacc catcttggat
     8401 gagttccgcc aggtggcagc cagtatcacc tatcaccagc ccaagttgct acttgtctcc
     8461 aacgtctccg ggaaagtggc cggccctgaa atcaccagac cagattactg ggtacgccat
     8521 gtccgtgagg cagtgcgctt tgccgatgga gtgaggacgc tgaatgaaca aggtgtcaat
     8581 atctttctgg aaatcggttc taccgctacc ctgttgggca tggcactgcg agtaaatgag
     8641 gaagattcaa atgcctcaaa aggaacttcg tcttgctacc tgcccagttt acgggaaagc
     8701 cagaaggatt gtcagcagat gttcactagt ctgggtgagt tgtacgtaca tggatatgat
     8761 attgattggg gtgcatttaa tcggggatat caaggacgca aggtgatatt gccaacctat
     8821 ccgtttcagc gacaacgtta ttggcttccc gaccctaagt tggcacaaag ttccgattta
     8881 gatacctttc aagctcagag cagcgcatca tcacaaaatc ctagcgctgt gtccacttta
     8941 ctgatggaat atttgcaagc aggtgatgtc caatctttag ttgggctttt ggatgatgaa
     9001 cggaaactct ctgctgctga acgaattgca ctacccagta ttttggagtt tttggtagag
     9061 gaacaacagc gacaaataag ctcaaccaca actcctcaaa cagttttaca aaaaataagt
     9121 caaacttccc atgaggacag atatgaaata ttgaagaacc tgatcaaatc tgaaatcgaa
     9181 acgattatca aaagtgttcc ctccgatgaa caaatgtttt ctgacttagg aattgattcc
     9241 ttgatggcga tcgaactgcg taataagctc cgttctgcta tagggttgga actgccagtg
     9301 gcaatagtat ttgaccatcc cacgattaag cagttaacta acttcgtact ggacagaatt
     9361 gtgccgcagg cagaccaaaa ggacgttccc accgaatcct tgtttgcttc taaacaggag
     9421 atatcagttg aggagcagtc ttttgcaatt accaagctgg gcttatcccc tgcttcccac
     9481 tccctgcatc ttcctccatg gacggttaga cctgcggtaa tggcagatgt aacaaaacta
     9541 agccaacttg aaagagaggc ctatggctgg atcggagaag gagcgatcgc cccgccccat
     9601 ctcattgccg atcgcatcaa tttactcaac agtggtgata tgccttggtt ctgggtaatg
     9661 gagcgatcag gagagttggg cgcgtggcag gtgctacaac cgacatctgt tgatccatat
     9721 acttatggaa gttgggatga agtaactgac caaggtaaac tgcaagcaac cttcgaccca
     9781 agtggacgca atgtgtatat tgtcgcgggt gggtctagca acctccccac ggtagccagc
     9841 cacctcatga cgcttcagac tttattgatg ctgcgggaaa ctggtcgtga cacaatcttt
     9901 gtctgtctgg caatgccagg ttatgccaaa taccacagtc aaacaggaaa atcgccggaa
     9961 gagtatattg cgctgactga cgaggatggt atcccaatgg acgagtttat tgcactttct
    10021 gtctacgact ggcctgttac cccatcgttt cgtgttctgc gagacggtta tccacctgat
    10081 cgagattctg gtggtcacgc agttagtacg gttttccagc tcaatgattt cgatggagcg
    10141 atcgaagaaa catatcgtcg tattatccgc catgccgatg tccttggtct cgaaagaggc
    10201 taaatttcag gcgttggtga atagaaccca cattccgcag ataaggtctt atgaataaaa
    10261 aacaggtaga cacattgtta atacacgctc atctttttac catgcagggc aatggcctgg
    10321 gatatattgc cgatggggca attgcggttc agggtagcca gatcgtagca gtggattcga
    10381 cagaggcttt gctgagtcat tttgaaggaa ataaaacaat taatgcggta aattgtgcag
    10441 tgttgcctgg actaattgat gctcatatac atacgacttg tgctattctg cgtggagtgg
    10501 cacaggatgt aaccaattgg ctaatggacg cgacaattcc ttatgcactt cagatgacac
    10561 ccgcagtaaa tatagccgga acgcgcttga gtgtactcga agggctgaaa gcaggaacaa
    10621 ccacattcgg cgattctgag actccttacc cgctctgggg agagtttttc gatgaaattg
    10681 gggtacgtgc tattctatcc cctgccttta acgcctttcc actagaatgg tcggcatgga
    10741 aggagggaga cctctatccc ttcgatatga aggcaggacg acgtggtatg gaagaggctg
    10801 tggattttgc ttgtgcatgg aatggagccg cagagggacg tatcaccact atgttgggac
    10861 tacaggcggc ggatatgcta ccactggaga tcctacacgc agctaaagag attgcccaac
    10921 gggaaggctt aatgctgcat attcatgtgg cccagggaga tcgagaaaca aaacaaattg
    10981 tcaaacgata tggtaagcgt ccgatcgcat ttctagctga aattggctac ttggacgaac
    11041 agttgctggc agttcacctc accgatgcca cagatgaaga agtgatacaa gtagccaaaa
    11101 gtggtgctgg catggcactc tgttcgggcg ctattggcat cattgacggt cttgttccgc
    11161 ccgctcatgt ttttcgacaa gcaggcggtt ccgttgcact cggttctgat caagcctgtg
    11221 gcaacaactg ttgtaacatc ttcaatgaaa tgaagctgac cgccttattc aacaaaataa
    11281 aatatcatga tccaaccatt atgccggctt gggaagtcct gcgtatggct accatcgaag
    11341 gagcgcaggc gattggttta gatcacaaga ttggctctct tcaagtgggc aaagaagccg
    11401 acctgatctt aatagacctc agttccccta acctctcgcc caccctgctc aaccctattc
    11461 gtaaccttgt acctaacttg gtgtatgctg cttcaggaca tgaagttaaa agcgtcatgg
    11521 tggcgggaaa acttttagtg gaagactacc aagtcctcac ggtagatgag tccgctattc
    11581 tcgctgaagc gcaagtacaa gctcaacaac tctgccaacg tgtgaccgct gaccccattc
    11641 acaaaaagat ggtgttaatg gaagcgatgg ctaagggtaa attatagata caggcttatc
    11701 tgcaacaaca tttctgaatc aaacctggag gggcaaacca atgaccatat atgaaaataa
    11761 gttgagtagt tatcaaaaaa atcaagatgc cataatatct gcaaaagaac tcgaagaatg
    11821 gcatttaatt ggacttctag accattcaat agatgcggta atagtaccga attattttct
    11881 tgagcaagag tgtatgacaa tttcagagag aataaaaaag agtaaatatt ttagcgctta
    11941 tcccggtcat ccatcagtaa gtagcttggg acaagagttg tatgaatgcg aaagtgagct
    12001 tgaattagca aagtatcaag aagacgcacc cacattgatt aaagaaatgc ggaggctggt
    12061 acatccgtac ataagtccaa ttgatagact tagggttgaa gttgatgata tttggagtta
    12121 tggctgtaat ttagcaaaac ttggtgataa aaaactgttt gcgggtatcg ttagagagtt
    12181 taaagaagat aaccctggcg caccacattg tgacgtaatg gcatggggtt ttctcgaata
    12241 ttataaagat aaaccaaata tcataaatca aatcgcagca aatgtatatt taaaaacgtc
    12301 tgcatcagga ggagaaatag tgctttggga tgaatggcca actcaaagcg aatatatagc
    12361 atacaaaaca gatgatccag ctagtttcgg tcttgatagc aaaaagatcg cacaaccaaa
    12421 acttgagatc caaccgaacc agggagattt aattctattc aattccatga gaattcatgc
    12481 ggtgaaaaag atagaaactg gtgtacgtat gacatgggga tgtttgattg gatactctgg
    12541 aactgataaa ccgcttgtta tttggactta atgtagcgtt tccatttgag tcaaggcacg
    12601 agaagcttct aaagctggaa tagatacact atcattctca actacactct caaatgtcct
    12661 aggtaactgt gccccaaaca tcagcattcc aatggcgttg aacaaaaaga aagccaacca
    12721 caagatatgg ttactctcaa atttaacagc agctacatcc gcaggtaaaa atcctacacc
    12781 aaacgcgatt aagttaacat tgcggagagt atgcccttga gccaaaccca agaagtaccc
    12841 acatagtatg caacatactg aattgcatac taggacaagt accaaccagg gaataaaaat
    12901 atcaatattc tcaataattt ctgcgtggtt ggttaacaac ccaaaaacat catcgggaaa
    12961 tagccaacac gctccgccga aaaccagact cactagcaga gccattccca cagaaacttt
    13021 tgccagaggt gctaactgtt ctgtggctcc tttcccttta aaatttcctg ccagagtttc
    13081 tgtacagaat cccaatcctt caacaatgta gatgctcaaa gcccatatct gtaagagcaa
    13141 ggcattttga gcgtagataa ttgtccccat ttgtgcccct tcgtagttaa acgttaagtt
    13201 ggtaaacata caaactaaat tgctgacaaa gatgtttcca ttgagagtta aggtggagcg
    13261 tatagctttt atgtcccaaa tttttccagc taattctttt acctcttgcc acgggatttc
    13321 tttgcagaca aaaaacaatc ccaccaatag ggtgagatat tgacttgcag cagaagctac
    13381 tcctgccccc atgctcgacc agtctaagtg gataataaac aagtagtcga gtgcgatatt
    13441 ggcagcattg cccacaaccg acaacaacac aactaagcca tttttttccc gtcccagaaa
    13501 ccagccaagc aggacaaagt tgagcaaaat ggcaggcgct ccccaactct gggtgttaaa
    13561 atacgcttga gctgaagact tcacctctgg gccgacatct agtatagaaa accccaacac
    13621 ccctaacggg tactgtaaca gtatgatcgc cacccccagc accagagcaa ttaaaccatt
    13681 aagcagtccc gccaacagta cgccctctcg gtcatctcgt ccgactgctt gtgctgttaa
    13741 cgcagtggta cccattcgta aaaacgataa aacaaagtag agaaagttaa gcaggtttcc
    13801 agcaagggct actccagcta ggtagtggat ttccgagaga tgacctaaga acatgatact
    13861 gactaaatta ctcagtggta ctataatatt cgataggacg ttggtaaaag ctagtcggaa
    13921 gtagcggggt ataaagtcat actggcttgg aaatgtcagg ctcataagat taatttgaca
    13981 gtagagttgt tggaaaataa gggataataa tcaagcagac aagtagggtg acattaatgt
    14041 tgaacttaga ccgcatcctg aatcaagagc gactgctacg agaaatgact ggacttaacc
    14101 gccaagcatt caacgagctg ttatctcagt ttgctgatac ctatgaacgc accgtgttca
    14161 actccttagc aaaccgcaaa cgtgcgcccg ggggcggacg caagcctaca ctcagaagta
    14221 tagaggaaaa actattttat atcctgctgt actgcaaatg ttatccgacg tttgacttgc
    14281 tgagtgtgtt gttcaacttt gaccgctcct gtgctcatga ttgggtacat cgactactgt
    14341 ctgtgctaga aaccacttta ggagaaaagc aagttttgcc agcacgcaaa ctcaggagca
    14401 tggaggaatt caccaaaagg tttccagatg tgaaggaggt gattgtggat ggtacggagc
    14461 gtccagtcca gcgtcctcaa aaccgagaac gccaaaaaga gtattactct ggcaagaaaa
    14521 agcggcatac atgcaagcag attacagtca gcacaaggga gaaacgagtg attattcgga
    14581 cggaaaccag agcaggtaaa gtgcatgaca aacggctact ccatgaatca gagatagtgc
    14641 aatacattcc tgatgaagta gcaatagagg gagatttggg ttttcatggg ttggagaaag
    14701 aatttgtcaa tgtccattta ccacacaaga aaccgaaagg tatcgaagca aggaggcatg
    14761 gcggcgggat gggtcagttt ttataagaga gttttgacaa tataaataaa agacttttga
    14821 caaccagact tggcattact tagtttcagt ctttcatctc aagtttacgt tattctgagg
    14881 cgaacatgaa tcttataaca acaaaaaaac aggtagatac attagtgata cacgctcatc
    14941 tttttaccat gcagggaaat ggtgtgggat atattgcaga tggggcactt gcggttgagg
    15001 gtagccgtat tgtagcagtt gattcgacgg aggcgttgct gagtcatttt gagggcagaa
    15061 aggttattga gtccgcgaat tgtgccgtct tgcctgggct gattaatgct cacgtagaca
    15121 caagtttggt gctgatgcgt ggggcggcgc aagatgtaac taattggcta atggacgcga
    15181 ccatgcctta ttttgctcac atgacacccg tggcgagtat ggctgcaaca cgcttaaggg
    15241 tggtagaaga gttgaaagca ggcacaacaa cattctgtga caataaaatt attagccccc
    15301 tgtggggcga atttttcgat gaaattggtg tacgggctag tttagctcct atgttcgatg
    15361 cactcccact ggagatgcca ccgcttcaag acggggagct ttatcccttc gatatcaagg
    15421 cgggacggcg ggcgatggca gaggctgtgg attttgcctg tgggtggaat ggggcagcag
    15481 aggggcgtat cactaccatg ttaggaatgt attcgccaga tatgatgccg cttgagatgc
    15541 tacgcgcagc caaagagatt gctcaacggg aaggcttaat gctgcatttt catgtagcgc
    15601 agggagatcg ggaaacagag caaatcgtta aacgatatgg taagcgtccg atcgcatttc
    15661 tagctgagat tggctacttg gacgaacagt tgctggcagt tcacctcacc gatgccaccg
    15721 atgaagaggt gatacaagta gccaaaagtg gcgctggcat ggtactctgt tcgggaatga
    15781 ttggcactat tgacggtatc gtgccgcccg ctcatgtgtt tcggcaagca ggcggacccg
    15841 ttgcgctagg cagcagctac aataatattt tccatgagat gaagctgacc gccttattca
    15901 acaaaataaa atatcacgat ccaaccatta tgccggcttg ggaagtcctg cgtatggcta
    15961 ccatcgaagg agcgcgggcg attggtttag atcacaagat tggctctctt gaagttggca
    16021 aagaagccga cctgatctta atagacctca gcacccctaa cctctcaccc actctgctta
    16081 accccattcg taaccttgta cctaatttcg tgtacgctgc ttcaggacat gaagttaaaa
    16141 gtgtcatggt ggcgggaaaa ctgttattgg aagactacca agtcctcaca gtagatgagt
    16201 ctgctatcat tgctgaagca caattgcaag cccaacagat ttctcaatgc gtagcatctg
    16261 accctatcca caaaaaaatg gtgctgatgg cggcgatggc aaggggccaa ttgtaggaat
    16321 ggtcttgagt tatctagtaa gctaagttgc caactaacaa ttaaaaatac gaagcaggtg
    16381 ataaggcaga attacagcag gttgtctttc ggatcgctcg ttggatcttt gtaccttccc
    16441 tagtcatggc gatcgccctc atcgtcttcg cccaacccgt gatgagcctg ttcggtgcag
    16501 agtttgctgt ggctcattgg tagccgatac catccctcca actgacttgt catgatagtc
    16561 atggtgcgac tttcccttcg gtactgataa actgggattg aatccctttc agagtcatca
    16621 tgatagattt gggaagtcta aatgtggtcg agaagaaagt gcttttccca tgttgagaat
    16681 agtcacatta acatcagcat caaaacgcct aattctagat tttacctatg gtttcagcca
    16741 aggtaaagga actgagtcta aattacacgc cgtcatgaga taatatgatt attaattttc
    16801 tgtatagccc agttaattat acttgattgt aggctatttt tagcctcttc taatgaagaa
    16861 tccagactaa tccttatgta cgggaatatg ttatgcaaga aaaacgaatc gcaatgtggt
    16921 ctgtgccacg aagtttgggt acagtgctgc tacaagcctg gtcgagtcgg ccagataccg
    16981 tagtctttga tgaacttctc tcctttccct atctctttat caaagggaaa gatatgggct
    17041 ttacttggac agaccttgat tctagccaaa tgccccacgc agattggcga tccgtcatcg
    17101 atctgttaaa ggctcccctg cctgaaggga aatcaatcat cgatctgtta aaggctcccc
    17161 tgcctgaagg gaaatcaatt tgctatcaga agcatcaagc gtatcattta atcgaagaga
    17221 ccatggggat tgagtggata ttgcccttca gcaactgctt tctgattcgc caacccaaag
    17281 aaatgctctt atcttttcgt aagattgtgc cacattttac ctttgaagaa acaggctgga
    17341 tcgaattaaa acggctgttt gactatgtac atcaaacgag cggagtaatc ccgcctgtca
    17401 tagatgcaca cgacttgctg aacgatccgc ggagaatgct ctccaagctt tgtcaggttg
    17461 taggggttga gtttaccgag acaatgctca gttggccccc catggaggtc gagttgaacg
    17521 aaaaactagc cccttggtac agcaccgtag caagttctac gcattttcac tcgtatcaga
    17581 ataaaaatga gtcgttgccg ctatatcttg tcgatatttg taaacgctgc gatgaaatat
    17641 atcaggaatt atatcaattt cgactttatt agagagtatt ggtaatgaaa attttgaatt
    17701 agtgaagaaa tagaagttga gaatatagac catctaggga tagagactta tgctggacgg
    17761 attcaacaac atcaggacaa ttacccacgt cagagtgatt ttagctttgc tgtttacgga
    17821 caattatgga tttatggcat ggaactatag gctgatttag ctctaagctt aattagtctt
    17881 aaacctcata aacgcctctt tttcaagcgt ggctttcagg ctctatccct tatgaaacaa
    17941 gctgtttgac cactttgtca cccggtaagg agaaaaacct taaacccaag cagaaaaaat
    18001 tagcccgtaa aaaaaaggga agtaaatcaa ggaaatatag ggtaatatat ttttcacaag
    18061 tttatcaatt gtaatctact tgattcagta aattaattaa ggtgttgaag agatgcaaac
    18121 aagaattgta aatagctgga atgagtggga tgaactaaag gagatggttg tcgggattgc
    18181 agatggtgct tattttgaac caactgagcc aggtaaccgc cctgctttac gcgataagaa
    18241 cattgccaaa atgttctctt ttcccagggg tccgaaaaag caagaggtaa cagagaaagc
    18301 taatgaggag ttgaatgggc tggtagcgct tctagaatca cagggcgtaa ctgtacgccg
    18361 cccagagaaa cataactttg gcctgtctgt gaagacacca ttctttgagg tagagaatca
    18421 atattgtgcg gtctgcccac gtgatgttat gatcaccttt gggaacgaaa ttctcgaagc
    18481 aactatgtca cggcggtcac gcttctttga gtatttaccc tatcgcaaac tagtctatga
    18541 atattggcat aaagatccag atatgatctg gaatgctgcg cctaaaccga ctatgcaaaa
    18601 tgccatgtac cgcgaagatt tctgggagtg tccgatggaa gatcgatttg agagtatgca
    18661 tgattttgag ttctgcgtca cccaggatga ggtgattttt gacgcagcag actgtagccg
    18721 ctttggccgt gatatttttg tgcaggagtc aatgacgact aatcgtgcag ggattcgctg
    18781 gctcaaacgg catttagagc cgcgtcgctt ccgcgtgcat gatattcact tcccactaga
    18841 tattttccca tcccacattg attgtacttt tgtcccctta gcacctgggg ttgtgttagt
    18901 gaatccagat cgccccatca aagagggtga agagaaactc ttcatggata acggttggca
    18961 attcatcgaa gcacccctcc ccacttccac cgacgatgag atgcctatgt tctgccagtc
    19021 cagtaagtgg ttggcgatga atgtgttaag catttccccc aagaaggtca tctgtgaaga
    19081 gcaagagcat ccgcttcatg agttgctaga taaacacggc tttgaggtct atccaattcc
    19141 ctttcgcaat gtctttgagt ttggcggttc gctccattgt gccacctggg atatccatcg
    19201 cacgggaacc tgtgaggatt acttccctaa actaaactat acgccggtaa ctgcatcaac
    19261 caatggcgtt tctcgcttca tcatttagta ggttttatag ttatgcaaaa gagagaaagc
    19321 ccacagatac tatttgatgg gaatggaaca caatctgagt ttccagatag ttgcattcac
    19381 cacttgttcg aggatcaagc cgcaaagcga ccggatgcga tcgctctcat tgacggtgag
    19441 caatccctta cctacgggga actaaatgta cgcgctaacc acctagccca gcatctcttg
    19501 tccctaggct gtcaacccga tgacctcctc gccatctgca tcgagcgttc ggcagaactc
    19561 tttattggtt tgttgggtat cctaaaagcc ggatgtgctt atgtgccttt ggatgtaggc
    19621 tatcctggcg atcgcataga gtatatgttg cgggactcgg atgcgcgtat tttactaacc
    19681 tcaacggatg tcgctaagaa acttgcctta accatacctg cattgcaaga gtgccaaacc
    19741 gtctatttag atcaagagat atttgagtat gattttcatt ttttagcgat agctaaacta
    19801 ttacataacc aatacttgag attattacat ttttattttt ataccttgat tcagcaatgc
    19861 caggcaactt cggtttccca agggattcag acacaggttc tccccaataa tctcgcttac
    19921 tgcatttaca cctctggctc taccggaaat cccaaaggga tcttgatgga acatcgctca
    19981 ctggtgaata tgctttggtg gcatcagcaa acgcggcctt cggttcaggg tgttaggacg
    20041 ctgcaatttt gtgcagtcag ctttgacttt tcctgccatg aaattttttc taccctctgt
    20101 cttggcggga tattggtctt ggtgccagag gcagtgcgcc aaaatccctt tgcattggct
    20161 gagttcatca gtcaacagaa aattgaaaaa ttgtttcttc ccgttatagc attactacag
    20221 ttggccgaag ctgtaaatgg gaataaaagc acctccctcg cgctttgcga agttatcact
    20281 accggggagc agatgcagat cacacctgct gtcgccaacc tctttcagaa aaccggggcg
    20341 atgttgcata atcactacgg ggcaacagaa tttcaagatg ccaccactca taccctcaag
    20401 ggcaatccag agggctggcc aacactggtg ccagtgggtc gtccactgca caatgttcaa
    20461 gtgtatattc tggatgaggc acagcaacct gtacctcttg gtggagaggg tgaattctgt
    20521 attggtggta ttggactggc tcgtggctat cacaatttgc ctgacctaac gaatgaaaaa
    20581 tttattccca atccatttgg ggctaatgag aacgctaaaa aactctaccg cacaggggac
    20641 ttggcacgct acctacccga cggcacgatt gagcatttag gacggataga ccaccaggtt
    20701 aagatccgag gtttccgcgt ggaattgggg gaaattgagt ccgtgctggc aagtcaccaa
    20761 gctgtgcgtg aatgtgccgt tgtggcacgg gagattgcag gtcatacaca gttggtaggg
    20821 tatatcatag caaaggatac acttaatctc agtttcgaca aacttgaacc tatcctgcgt
    20881 caatattcgg aagcggtgct gccagaatac atgataccca ctcggttcat caatatcagt
    20941 aatatgccgt tgactcccag tggtaaactt gaccgcaggg cattacctga tcccaaaggc
    21001 gatcgccctg cattgtctac cccacttgtc aagcctcgta cccagacaga gaaacgttta
    21061 gcagagattt ggggcagtta tcttgctgta gatattgtgg gaacccacga caatttcttt
    21121 gatctaggcg gtacgtcact gctattgact caagcgcaca aattcctgtg cgagaccttt
    21181 aatattaatt tgtccgctgt ctcactcttt caatatccca caattcagac attggcacaa
    21241 tatattgatt gccaaggaga cacaacctca agcgatacag catccaggca caagaaagta
    21301 cgtaaaaagc agtccggtga cagcaacgat attgccatca tcagtgtggc aggtcgcttt
    21361 ccgggtgctg aaacgattga gcagttctgg cataatctct gtaatggtgt tgaatccatc
    21421 acccttttta gtgatgatga gctagagcag actttgcctg agttatttaa taatcccgct
    21481 tatgtcaaag caggtgcggt gctagaaggc gttgaattat ttgatgctac cttttttggc
    21541 tacagcccca aagaagctgc ggtgacagac cctcagcaac ggattttgct agagtgtgcc
    21601 tgggaagcat ttgaacgggc tggctacaac cccgaaacct atccagaacc agttggtgtt
    21661 tatgctggtt caagcctgag tacctatctg cttaacaata ttggctctgc tttaggcata
    21721 attaccgagc aaccctttat tgaaacggat atggagcagt ttcaggctaa aattggcaat
    21781 gaccggagct atcttgctac acgcatctct tacaagctga atctcaaggg tccaagcgtc
    21841 aatgtgcaga ccgcctgctc aacctcgtta gttgcggttc acatggcctg tcagagtctc
    21901 attagtggag agtgtcaaat ggctttagcc ggtggtattt ctgtggttgt accacagaag
    21961 gggggctatc tctacgaaga aggcatggtt cgttcccagg atggtcattg tcgcgccttt
    22021 gatgccgaag cccaagggac tatatttggc aatggcggcg gcttggtttt gcttaaacgg
    22081 ttgcaggatg cactggacga taacgacaac attatggcag tcatcaaagc cacagccatc
    22141 aacaacgacg gtgcgctcaa gatgggctac acagcaccga gcgtggatgg gcaagctgat
    22201 gtaattagcg aggcgattgc tatcgctgac atagatgcaa gcaccattgg ctatgtagaa
    22261 gctcatggca cagccaccca attgggtgat ccgattgaag tagcagggtt agcaagggca
    22321 tttcagcgta gtacggacag cgtccttggt aaacaacaat gcgctattgg atcagttaaa
    22381 actaatattg gccacttaga tgaggcggca ggcattgccg gactgataaa ggctgctcta
    22441 gctctacaat atggacagat tccaccgagc ttgcactatg ccaatcctaa tccacggatt
    22501 gattttgacg caaccccatt ttttgtcaac acagaactac gcgaatggtc aaggaatggt
    22561 tatcctcggc gggcgggggt gagttctttt ggtgtgggtg gaactaacag ccatattgtg
    22621 ctggaggagt cgcctgtaaa gcaacccaca ttgttctctt ctttgccaga acgcagtcat
    22681 catctgctga cgctttctgc ccatacacaa gaggctttgc atgagttggt gcaacgctac
    22741 atccaacata acgagacaca ccttgatatt aacttaggcg acctctgttt cacagccaat
    22801 acgggacgca agcattttga gcatcgccta gcggttgtag ccgaatcaat ccctggctta
    22861 caggcacaac tggaaactgc acagactgcg atttcagcac agaaaaaaaa tgccccgccg
    22921 acgatcgcat tcctgtttac aggtcaaggc tcacaataca ttaacatggg gcgcaccctc
    22981 tacgatactg aatcaacatt ccgtgcagcc cttgaccgat gtgaaaccat tctccaaaat
    23041 ttagggatcg agtccattct ctccgttatt tttggttcat ctgagcatgg actctcatta
    23101 gatgacacag cctataccca gcccgcactc tttgccatcg aatacgcgct ctatcaatta
    23161 tggaagtcgt ggggcatcca gccctcagtg gtgataggtc atagtgtagg tgaatatgtg
    23221 tccgcttgtg tggcgggagt ctttagctta gaggatgggt tgaaactgat tgcagaacga
    23281 ggacgactga tacaggcact tcctcgtgat gggagcatgg tttccgtgat ggcaagcgag
    23341 aagcgtattg cagatatcat tttaccttat gggggacagg tagggatcgc cgcgattaat
    23401 ggcccacaaa gtgttgtaat ttctgggcaa cagcaagcga ttgatgctat ttgtgccatc
    23461 ttggaaactg agggcatcaa aagcaagaag ctaaacgtct cccatgcctt ccactcgccg
    23521 ctagtggaag caatgttaga ctctttcttg caggttgcac aagaggtcac ttactcgcaa
    23581 cctcaaatca agcttatctc taatgtaacg ggaacattgg caagccatga atcttgtccc
    23641 gatgaacttc cgatcaccac cgcagagtat tgggtacgtc atgtgcgaca gcccgtccgg
    23701 tttgcggcgg gaatggagag ccttgagggt caaggggtaa acgtatttat agaaatcggt
    23761 cctaaacctg ttcttttagg catgggacgc gactgcttgc ctgaacaaga gggactttgg
    23821 ttgcctagtt tgcgcccaaa acaggatgat tggcaacagg tgttaagtag tttgcgtgat
    23881 ctatacttag caggtgtaac cgtagattgg agcagtttcg atcaggggta tgctcgtcgc
    23941 cgtgtgccac taccgactta tccttggcag cgagagcggc attgggtaga gccaattatt
    24001 cgtcaacggc aatcagtatt acaagccaca aataccacca agctaactcg taacgccagc
    24061 gtggcgcagc atcctctgct tggtcaacgg ctgcatttgt cgcggactca agagatttac
    24121 tttcaaacct tcatccactc cgacttccca atatgggttg ctgatcataa agtatttgga
    24181 aatgtcatca ttccgggtgt cgcctatttt gagatggcac tggcagcagg gaaggcactt
    24241 aaaccagaca gtatattttg gctcgaagat gtatccatcg cccaagcact gattattccc
    24301 gatgaagggc aaactgtgca aatagtatta agcccacagg aagagtcagc ttattttttt
    24361 gaaatcctct ctttagaaaa agaaaactct tgggtgcttc atgcctctgg taagctagtc
    24421 gcccaagagc aagtgctaga aaccgagcca attgacttga ttgcgttaca ggcacattgt
    24481 tccgaagaag tgtcagtaga tgtgctatat caggaagaaa tggcgcgccg gctggatatg
    24541 ggtccaatga tgcgtggggt gaagcagctt tggcgttatc cgctctcctt tgccaaaagt
    24601 catgatgcga tcgcactcgc caaggtcagc ttgccagaaa tcttgcttca tgagtccaat
    24661 gcctaccaat tccatcctgt aatcttggat gcggggctgc aaatgataac ggtctcttat
    24721 cctgaagcaa accaaggcca gacttatgta cctgttggta tagagggtct acaagtctat
    24781 ggtcgtccca gttcagaact ttggtgtcgc gcccaatatc ggcctccttt ggatacagat
    24841 caaaggcagg gtattgattt gctgccaaag aaattgattg cagacttgca tctatttgat
    24901 acccagggtc gtgtggttgc catcatgttt ggtgtgcaat ctgtccttgt gggacgggaa
    24961 gcaatgttgc gatcgcaaga tacttggcga aattggcttt atcaagtcct gtggaaacct
    25021 caagcctgtt ttggactttt accgaattac ctgccaaccc cagataagat tcggaaacgc
    25081 ctggaaacaa agttagcgac attgatcatc gaagctaatt tggcgactta tgcgatcgcc
    25141 tatacccaac tggaaaggtt aagtctagct tacgttgtgg cggctttccg acaaatgggc
    25201 tggctgtttc aacccggtga gcgtttttcc accgcccaga aggtatcagc gttaggaatc
    25261 gttgatcaac atcggcaact attcgctcgt ttgctcgaca ttctagccga agcagacata
    25321 ctccgcagcg aaaacttgat gacgatatgg gaagtcattt catacccgga aacgattgat
    25381 atacaggtac ttcttgacga cctcgaagcc aaagaagcag aagccgaagt cacactggtt
    25441 tcccgttgca gtgcaaaatt ggccgaagta ttacaaggaa aatgtgaccc catacagttg
    25501 ctctttcccg caggggacac aacaacgtta agcaaactct atcgtgaagc cccagttttg
    25561 ggtgttacta atactctagt ccaagaagcg cttctttccg ccctggagca gttgccgccg
    25621 gaacgtggtt ggcgaatttt agagattggt gctggaacag gtggaaccac agcctacttg
    25681 ttaccgcatc tgcctgggga tcagacaaaa tatgtcttta ccgatattag tgcctttttt
    25741 cttgccaaag cggaagagcg ttttaaagat tacccgtttg tacgttatca ggtattagat
    25801 atcgaacaag caccacaggc gcaaggattt gaaccccaaa tatacgattt aatcgtagca
    25861 gcggatgtct tgcatgctac tagtgacctg cgtcaaactc ttgtacatat ccggcaatta
    25921 ttagcgccgg gcgggatgtt gatcctgatg gaagacagcg aacccgcacg ctgggctgat
    25981 ttaacctttg gcttaacaga aggctggtgg aagtttacag accatgactt acgccccaac
    26041 catccgctat tgtctcctga gcagtggcaa atcttgttgt cagaaatggg atttagtcaa
    26101 acaaccgcct tatggccaaa aatagatagc ccccataaat tgccacggga ggcggtgatt
    26161 gtggcgcgta atgaaccagc catcagaaaa ccccgaagat ggctgatctt ggctgacgag
    26221 gagattggtg gactactagc caaacagcta cgtgaagaag gagaagattg tatactcctc
    26281 ttgccagggg aaaagtacac agagagagat tcacaaacgt ttacaatcaa tcctggagat
    26341 attgaagagt ggcaacagtt attgaaccga gtaccgaaca tacaagaaat tgtacattgt
    26401 tggagtatgg tttccactga cttagataga gccactattt tcagttgcag cagtacgctg
    26461 catttagttc aagcattagc aaactatcca aaaaaccctc gcttgtcact tgtcacccta
    26521 ggcgcacaag ccgttaacga acatcatgtt caaaatgtag ttggagcagc cctctggggc
    26581 atgggaaagg taattgcact cgaacaccca gagctacaag tagcacaaat ggatttagac
    26641 ccgaatggga aggttaaggc gcaagtagaa gtgcttaggg atgaacttct cgccagaaaa
    26701 gaccctgcat cagcaatgtc tgtgcctgat ctgcaaacac gacctcatga aaagcaaata
    26761 gcctttcgtg agcaaacacg ttatgtggca agactttcgc ccttagaccg ccccaatcct
    26821 ggagagaaag gcacacaaga ggctcttacc ttccgtgatg atggcagcta tctgattgct
    26881 ggtggtttag gcggactggg gttagtggtg gctcgttttc tggttacaaa tggggctaaa
    26941 taccttgtgc tagtcggacg acgtggtgcg agggaggaac agcaagctca attaagcgaa
    27001 ctagagcaac tcggagcttc cgtgaaagtt ttacaagccg atattgctga tgcagaacaa
    27061 ctagcccaag cactttcagc agtaacctac ccaccattac ggggtgttat tcatgcggca
    27121 ggtacattga acgatgggat tctacagcag caaagttggc aagcctttaa agaagtgatg
    27181 aatcccaagg tagcaggtgc gtggaaccta catatactga caaaaaatca gcctttagac
    27241 ttctttgtcc tgttctcctc cgccacctct ttgttaggta acgctggaca agccaatcac
    27301 gccgccgcaa atgctttcct tgatgggtta gcctcctatc gtcgtcactt aggactaccg
    27361 agcctctcga ttaattgggg gacatggagc gaagtgggaa ttgcggctcg acttgaacta
    27421 gataagttgt ccagcaaaca gggagaggga accattacgc taggacaggg cttacaaatt
    27481 cttgagcagt tgctcaaaga cgagaatggg gtgtatcaag tgggtgtcat gcctatcaac
    27541 tggacacaat tcttagcaag gcaattgact ccgcagccgt tcttcagcga tgccatgaag
    27601 agtattgaca cctctgtagg taaactaacc ttgcaggagc gggactcttg cccccaaggt
    27661 tacgggcata atattcgaga gcaattagag aacgctccgc ccaaagaggg tctgactctc
    27721 ttgcaggctc atgttcggga gcaggtttcc caagttttgg ggatagacac gaagacatta
    27781 ttggcagaac aagacgtggg tttctttacc ctggggatgg attcgctgac ctctgtcgag
    27841 ttaagaaaca ggttacaagc cagtttgggc tgctctcttt cttccacttt ggcttttgac
    27901 tatccaacac aacaggctct tgtgaattat cttgccaatg aattgctggg aacccctgag
    27961 cagctacaag agcctgaatc tgatgaagaa gatcagatat cgtcaatgga tgacatcgtg
    28021 cagttgctgt ccgcgaaact agagatggaa atttaagccc atggatgaaa aactaagaac
    28081 atacgaacga ttaatcaagc aatcctatca caagatagag gctctggaag ctgaagttaa
    28141 caggttgaag caaacccaat gtgaacctat cgccatcgtc ggcatgggct gtcgttttcc
    28201 tggtgcgaat agtccagaag cgttttggca gttgttgtgt gatggggttg atgctattcg
    28261 tgagatacca aaaaatcgat gggttgttga tgcctacata gatgaaaatt tggaccgcgc
    28321 agacaagaca tcaatgcgat ttggcgggtt tgtcgagcaa cttgagaagt ttgatgccca
    28381 attctttggc atatcaccgc gagaagcggt ttctcttgac cctcagcaac gtttgttatt
    28441 agaagtaagt tgggaagcac tggaaaatgc agcggtgata ccaccttcgg caacgggcgt
    28501 attcgtcggt attagtaacc ttgattatcg tgaaacgctc ttgaagcaag gagcaattgg
    28561 tacttatttt gcttcgggta atgcccatag cacagccagt ggtcgcttgt cttactttct
    28621 cggtctgaca ggcccctgtc tctcgataga tacagcttgt tcttcgtcgt tggtcgctgt
    28681 acatcagtca ctgataagtc tgcgtcagcg agaatgtgac ttagcgttgg ttgggggagt
    28741 ccatcggctg atagccccag aggaaagtgt ctcgttagca aaagcccata tgttatctcc
    28801 cgatggtcgt tgcaaagtct ttgatgcgtc ggcaaacggg tatgtccgag ccgaaggatg
    28861 tggcatgata gtcctcaaac gattatcgga cgcgcaagct gatggggata aaatcttggc
    28921 gttgattcgc gggtcagcca taaatcaaga cggtcgcacg agtggcttga ccgttccaaa
    28981 tggtccccaa caagccgacg tgattcgcca agccctcgcc aatagtggca taagaccaga
    29041 acaagttaac tatgtagaag ctcatggcac agggacttcc ctaggagacc cgattgaggt
    29101 cggcgcgttg ggaacgatct ttaatcaacg ctcccaacct ttaattattg gttcagttaa
    29161 aacaaatatt gggcatctag aagcagcagc agggattgct ggactgatta aagtcgtcct
    29221 tgccatgcag catggagaaa ttccacctaa tttacacttt caccagccca atcctcgcat
    29281 taactgggat aaattgccaa tcaggatccc cacagaacga acagcttggc ctactggcga
    29341 tcgcatcgca gggataagtt ctttcggctt tagtggcact aattctcatg tcgtgttaga
    29401 ggaagcccca aaaatagagc cgtctacttt agagattcat tcaaagcagt atgtttttac
    29461 cttatcagca gcgacacctc aagcactaca agaacttact cagcgttatg taacttatct
    29521 cactgaacac ttacaagaga gtctggcgga tatttgcttt acagccaaca cagggcgcaa
    29581 acactttaga catcgctttg cagtagtagc agagtctaaa acccagttgc gccaacaatt
    29641 ggaaacgttt gcccaatcgg gagaggggca ggggaagagg acatctctct caaaaatagc
    29701 ttttctcttt acaggtcaag gctcacagta tgtggggatg gggcaagaac tttatgagag
    29761 ccaacccacc ttccggcaaa ccattgaccg atgtgatgag attcttcgtt cactgttggg
    29821 caaatcaatc ctctcaatac tctatcccag ccaacaaatg ggattggaaa cgccatccca
    29881 aattgatgaa accgcctata ctcaacccac tcttttttct cttgaatatg cactggcgca
    29941 gttgtggcgc tcctggggta ttgagcctga tgtggtgatg gggcatagtg tgggagaata
    30001 tgtggccgct tgtgtggcgg gtgtcttttc tttagaggat ggactcaaac taattgctga
    30061 aagaggccgt ctgatgcaag aattgcctcc cgatggggcg atggtttcag ttatggccaa
    30121 taaatcgcgc atagagcaag caattcaatc tgtcagccga gaggtttcta ttgcggccat
    30181 caatggacct gagagtgtgg ttatctctgg taaaagggag atattacaac agattaccga
    30241 acatctggtt gccgaaggca ttaagacacg ccaactgaag gtctctcatg cctttcactc
    30301 accattgatg gagccaatat taggtcagtt ccgccgagtt gccaatacca tcacctatcg
    30361 gccaccgcaa attaaccttg tctcaaatgt cacaggcgga caggtgtata aagaaatcgc
    30421 tactcccgat tattgggtga gacatctgca agagactgtc cgttttgcgg atggggttaa
    30481 ggtgttacat gaacagaatg tcaatttcat gctcgaaatt ggtcccaaac ccacactgct
    30541 gggcatggtt gagttacaaa gttctgagaa tccattttct atgccaatga tgatgcccag
    30601 tttgcgtcag aatcgtagcg actggcagca gatgttggag agcttgagtc aactctatgt
    30661 tcatggtgtt gagattgact ggatcggttt taataaagac tatgtgcgac ataaagttgt
    30721 cctgccgaca tacccatggc agaaggagcg ttactgggta gaattggatc aacagaagca
    30781 cgccgctaaa aatctacatc ctctactgga caggtgcatg aagctgcctc gtcataacga
    30841 aacaattttt gagaaagaat ttagtctaga gacattgccc tttcttgctg actatcgcat
    30901 ttatggttca gttgtgtcgc caggtgcaag ttatctatca atgatactaa gtattgccga
    30961 gtcgtatgca aatggtcatt tgaatggagg gaatagtgca aagcaaacca cttatttact
    31021 aaaggatgtc acattcccag tacctcttgt gatctctgat gaggcaaatt acatggtgca
    31081 agttgcttgt tctctctctt gtgctgcgcc acacaatcgt ggcgacgaga cgcagtttga
    31141 attgttcagt tttgctgaga atgtacctga aagtagcagt ataaatgctg attttcagac
    31201 acccattatt catgcaaaag ggcaatttaa gcttgaagat acagcacctc ctaaagtgga
    31261 gctagaagaa ctacaagcgg gttgtcccca agaaattgat ctcaaccttt tctatcaaac
    31321 attcacagac aaaggttttg tttttggatc tcgttttcgc tggttagaac aaatctgggt
    31381 gggcgatgga gaagcattgg cgcgtctgcg acaaccggaa agtattgaat cgtttaaagg
    31441 atatgtgatt catcccggtt tgttggatgc ctgtacacaa gtcccatttg caatttcgtc
    31501 tgacgatgaa aataggcaat cagaaacgac aatgcccttt gcgctgaatg aattacgttg
    31561 ttatcagcct gcaaacggac aaatgtggtg ggttcatgca acagaaaaag atagatatac
    31621 atgggatgtt tctctgtttg atgagagcgg gcaagttatt gcggaattta taggtttaga
    31681 agttcgtgct gctatgcccg aaggcttact aagggcagac ttttggcata actggctcta
    31741 tacagtgaat tggcgatcgc aacctctaca aatcccagag gtgctggata ttaataagac
    31801 aggtgcagaa acatggcttc tttttgcaca accagaggga ataggagcgg acttagccga
    31861 atatttgcag agccaaggaa agcactgtgt ttttgtagtg cctgggagtg agtatacagt
    31921 gaccgagcaa cacattggac gcactggaca tcttgatgtg acgaaactga caaaaattgt
    31981 cacgatcaat cctgcttctc ctcatgacta taaatatttt ttagaaactc tgacggacat
    32041 tagattacct tgtgaacata tactctattt atggaatcgt tatgatttaa caaatacttc
    32101 taatcatcgg acagaattga ctgtaccaga tatagtctta aacttatgta ctagtcttac
    32161 ttatttggta caagccctta gccacatggg tttttccccg aaattatggc taattacaca
    32221 aaatagtcaa gcggttggta gtgacttagc gaatttagaa atcgaacaat ccccattatg
    32281 ggcattgggt cgaagcatcc gcgccgaaca ccctgaattt gattgccgtt gtttagattt
    32341 tgacacgctc tcaaatatcg caccactctt gttgaaagag atgcaagcta tagactatga
    32401 atctcaaatt gcttaccgac aaggaacgcg ctatgttgca cgactaattc gtaatcaatc
    32461 agaatgtcac gcaccgattc aaacaggaat ccgtcctgat ggcagctatt tgattacagg
    32521 tggattaggc ggtctaggat tgcaggtagc actcgccctt gcggacgctg gagcaagaca
    32581 cttgatcctc aatagtcgcc gtggtacggt ctccaaagaa gcccagttaa ttattgaccg
    32641 actacgccaa gaggatgtta gggttgattt gattgcggca gatgtctctg atgcggcaga
    32701 tagcgaacga ctcttagtag aaagtcagcg caagacctct cttcgaggga ttgtccatgt
    32761 tgcgggagtc ttggatgatg gcatcctgct ccaacaaaat caagagcgtt ttgaaaaagt
    32821 gatggcggct aaggtacgcg gagcttggca tctggaccaa cagagccaaa ccctcgattt
    32881 agatttcttt gttgcgttct catctgttgc gtcgctcata gaagaaccag gacaagccaa
    32941 ttacgccgca gcgaatgcgt ttttggattc attaatgtat tatcgtcaca taaagggatc
    33001 taatagcttg agtatcaact ggggggcttg ggcagaagtc ggcatggcag ccaatttatc
    33061 atgggaacaa cggggaatcg cggcaatttc tccaaagcaa gggaggcata ttctcgtcca
    33121 acttattcaa aaacttaatc agcatacaat cccccaagtt gctgtacaac cgaccaattg
    33181 ggctgaatat ctatcccatg atggcgtgaa tatgccattc tatgaatatt ttacacacca
    33241 cttgcgtaac gaaaaagaag ccaaattgcg gcaaacagca ggcagcacct cagaggaagt
    33301 cagtctgcgg caacagcttc aaacactctc agagaaagac cgggatgccc ttttgatgga
    33361 acatcttcaa aaaactgcga tcagagttct cggtttggca tctaatcaaa aaattgatcc
    33421 ctatcaggga ttgatgaata tgggactaga ctctttgatg gcggttgaat ttcggaatca
    33481 cttgatacgt agtttagaac gccctctgcc agccactctg ctctttaatt gcccaacact
    33541 tgattcattg catgattacc tagtcgcaaa aatgtttgat gatgcccctc agaaggcaga
    33601 gcaaatggca caaccaacaa cactgacagc acacagcata tcaatagaat ccaaaataga
    33661 tgataacgaa agcgtggatg acattgcaca aatgctggca caagcactca atatcgcctt
    33721 tgagtagcaa tgggcagccc ttaacctttc aaggtgacta atcaatagac ctcttgcaca
    33781 attgtttctg tggtacaata agtggtttta ggttttatgt atatttgggt gttgttgcga
    33841 tagctacgct cgccgaaggc atcacaaatt caaagatagg cgtgtgattc taacttttag
    33901 cttaacgggt gacaaggcgg ctaaagagct tgtttcataa gggatagagc ctgaaagccc
    33961 cgttgaaaaa agaggcgttt atgaggcttg agattgatta aattcagagc taaatcagcc
    34021 cataattcca taccataaat ccatagttgt ccgtagagac caaagctaaa atcactttga
    34081 cgtgggtact tgtcctgatg ttgttgaatc ccacattcag catgagtaaa tatactcaaa
    34141 atatttttcc cagcaggtta agtgttctaa tcctaagtct gatatcttat ttttgataag
    34201 ggacttaccg cgtaatagtt aaatttttgt atagcctaat tttacttggt ttaaggctct
    34261 tttttgctct tttggtgaat tattcaggat aatcaaagat gagtcagccc aattatggca
    34321 ttttgatgaa aaatgcgttg aacgaaataa atagcctacg atcgcaacta gctgcggtag
    34381 aagcccaaaa aaatgagtct attgccattg ttggtatgag ttgccgtttt ccaggcggtg
    34441 caactactcc agagcgtttt tgggtattac tgcgcgaggg tatatcagcc attacagaaa
    34501 tccctgctga tcgctgggat gttgataaat attatgatgc tgaccccaca tcgtccggta
    34561 aaatgcatac tcgttacggc ggttttctga atgaagttga tacatttgag ccatcattct
    34621 ttaatattgc tgcccgtgaa gccgttagca tggatccaca gcaacgcttg ctacttgaag
    34681 tcagttggga agctctggaa tccggtaata ttgttcctgc aactcttttt gatagttcca
    34741 ctggtgtatt tatcggtatt ggtggtagca actacaaatc tttaatgatc gaaaacagga
    34801 gtcggatcgg gaaaaccgat ttgtatgagt taagtggcac tgatgtgagt gttgctgccg
    34861 gcaggatatc ctatgtcctg ggtttgatgg gtcccagttt tgtgattgat acagcttgtt
    34921 catcttcttt ggtctcagtt catcaagcct gtcagagtct gcgtcagaga gaatgtgatc
    34981 tagcactagc tggtggagtc ggtttactca ttgatccaga tgagatgatt ggtctttctc
    35041 aaggggggat gctggcacct gatggtagtt gtaaaacatt tgatgccaat gcaaatggct
    35101 atgtgcgagg cgaaggttgt gggatgattg ttctaaaacg tctctcggat gcaacagccg
    35161 atggggataa tattcttgcc atcattcgtg ggtctatggt taatcatgat ggtcatagca
    35221 gtggtttaac tgctccaaga ggccccgcac aagtctctgt cattaagcaa gccttagata
    35281 gagcaggtat tgcaccggat gccgtaagtt atttagaagc ccatggtaca ggcacacccc
    35341 ttggtgatcc tatcgagatg gattcattga acgaagtgtt tggtcggaga acagaaccac
    35401 tttgggtcgg ctcagttaag acaaatattg gtcatttaga agccgcgtcc ggtattgcag
    35461 ggctgattaa ggttgtcttg atgctaaaaa acaagcagat tcctcctcac ttgcatttca
    35521 agacaccaaa tccatatatt gattggaaaa atctcccggt cgaaattccg accacccttc
    35581 atgcttggga tgacaagaca ttgaaggaca gaaagcgaat tgcaggggtt agttctttta
    35641 gtttcagtgg tactaacgcc cacattgtat tatctgaagc cccatctagc gaactaatta
    35701 gtaatcatgc ggcagtggaa agaccatggc acttgttaac ccttagtgct aagaatgagg
    35761 aagcgttggc taacttggtt gggctttatc agtcatttat ttctactact gatgcaagtc
    35821 ttgccgatat atgctacact gctaatacgg cacgaaccca tttttctcat cgccttgctc
    35881 tatcggctac ttcacacatc caaatagagg ctcttttagc cgcttataag gaagggtcgg
    35941 tgagtttgag catcaatcaa ggttgtgtcc tttccaacag tcgtgcgccg aaggtcgctt
    36001 ttctctttac aggtcaaggt tcgcaatatg tgcaaatggc tggagaactt tatgagaccc
    36061 agcctacttt ccgtaattgc ttagatcgct gtgccgaaat cttgcaatcc atcttttcat
    36121 cgagaaacag cccttgggga aacccactgc tttcggtatt atatccaaac catgagtcaa
    36181 aggaaattga ccagacggct tatacccaac ctgccctttt tgctgtagaa tatgccctag
    36241 cacagatgtg gcggtcgtgg ggaatcgagc cagatatcgt aatgggtcat agcataggtg
    36301 aatatgtggc agcttgtgtg gcggggatct tttctctgga ggatggtctc aaacttgctg
    36361 ccgaaagagg ccgtttgatg caggcgctac cacaaaatgg cgagatggtt gctatatcgg
    36421 cctcccttga ggaagttaag ccggctattc aatctgacca gcgagttgtg atagcggcgg
    36481 taaatggacc acgaagtgtc gtcatttcgg gcgatcgcca agctgtgcaa gtcttcacca
    36541 acaccctaga agatcaagga atccggtgca agagactgtc tgtttcacac gctttccact
    36601 ctccattgat gaaaccaatg gagcaggagt tcgcacaggt ggccagggaa atcaactata
    36661 gtcctccaaa aatagctctt gtcagtaatc taaccggcga cttgatttca cctgagtctt
    36721 ccctggagga aggagtgatc gcttcccctg gttactgggt aaatcattta tgcaatcctg
    36781 tcttgttcgc tgatggtatt gcaactatgc aagcgcagga tgtccaagtc ttccttgaag
    36841 ttggaccaaa accgacctta tcaggactag tgcaacaata ttttgacgag gttgcccata
    36901 gcgatcgccc tgtcaccatt cccaccttgc gccccaagca acccaactgg cagacactat
    36961 tggagagttt gggacaactg tatgcgcttg gtgtccaggt aaattgggcg ggctttgata
    37021 gagattacac cagacgcaaa gtaagcctac ccacctatgc ttggaagcgt caacgttatt
    37081 ggctagagaa acagtccgct ccacgtttag aaacaacaca agttcgtccc gcaactgcca
    37141 ttgtagagca tcttgaacaa ggcaatgtgc cgaaaatcgt ggacttgtta gcggcgacgg
    37201 atgtactttc aggcgaagca cggaaattgc tacccagcat cattgaacta ttggttgcaa
    37261 aacatcgtga ggaagcgaca cagaagccca tctgcgattg gctttatgaa gtggtttggc
    37321 aaccccagtt gctgacccta tctaccttac ctgctgtgga aacagagggt agacaatggc
    37381 tcatcttcgc cgatgctagt ggacacggtg aagcacttgc ggctcaatta cgtcagcaag
    37441 gggatataat tacgcttgtc tatgctggtc taaaatatca ctcggctaat aataaacaaa
    37501 ataccggggg ggacatccca tattttcaga ttgatccgat ccaaagggag gattatgaaa
    37561 ggttgtttgc tgctttgcct ccactgtatg gtattgttca tctttggagt ttagatatac
    37621 ttagcttgga caaagtatct aacctaattg aaaatgtaca attaggtagt ggcacgctat
    37681 taaatttaat acagacagtc ttgcaacttg aaacgcccac ccctagcttg tggctcgtga
    37741 caaagaacgc gcaagctgtg cgtaaaaacg atagcctagt cggagtgctt cagtcaccct
    37801 tatggggtat gggtaaggtg atagccttag aacaccctga actcaactgt gtatcaatcg
    37861 accttgatgg tgaagggctt ccagatgaac aagccaagtt tctggcggct gaactccgcg
    37921 ccgcctccga gttcagacat accaccattc cccacgaaag tcaagttgct tggcgtaata
    37981 ggactcgcta tgtgtcacgg ttcaaaggtt atcagaagca tcccgcgacc tcatcaaaaa
    38041 tgcctattcg accagatgcc acttatttga tcacgggcgg ctttggtggt ttgggcttgc
    38101 ttgtggctcg ttggatggtt gaacaggggg ctacccatct atttctgatg ggacgcagcc
    38161 aacccaaacc agccgcccaa aaacaactgc aagagatagc cgcgctgggt gcaacagtga
    38221 cggtggtgca agccgatgtt ggcatccgct cccaagtagc caatgtgttg gcacagattg
    38281 ataaggcata tcctttggct ggtattattc atactgccgg tgtattagac gacggaatct
    38341 tattgcagca aaattgggcg cgttttagca aggtgttcgc ccccaaacta gagggagctt
    38401 ggcatctaca tacactgact gaagagatgc cgcttgattt ctttatttgt ttttcctcaa
    38461 cagcaggatt gctgggcagt ggtggacaag ctaactatgc tgctgccaat gcctttttag
    38521 atgcctttgc ccatcatcgg cgaatacaag gcttgccagc tctctcgatt aactgggacg
    38581 cttggtctca agtgggaatg acggtacgtc tccaacaagc ttcttcacaa agcaccacag
    38641 ttgggcaaga tattagcact ttggaaattt caccagaaca gggattgcaa atctttgcct
    38701 atcttctgca acaaccatcc gcccaaatag cggccatttc taccgatggg cttcgcaaga
    38761 tgtacgacac aagctcggcc ttttttgctt tacttgatct tgacaggtct tcctccacta
    38821 cccaggagca atctacactt tctcatgaag ttggccttac cttactcgaa caattgcagc
    38881 aagctcggcc aaaagagcga gagaaaatgt tactgcgcca tctacagacc caagttgctg
    38941 cggtcttgcg tagtcccgaa ctgcccgcag ttcatcaacc cttcactgac ttggggatgg
    39001 attcgttgat gtcacttgaa ttgatgcggc gtttggaaga aagtctgggg attcagatgc
    39061 ctgcaacgct tgcattcgat tatcctatgg tagaccgttt ggctaagttt atactgactc
    39121 aaatatgtat aaattctgag ccagatacct cagcagttct cacaccagat ggaaatgggg
    39181 aggaaaaaga cagtaataag gacagaagta ccagcacttc cgttgactca aatattactt
    39241 ccatggcaga agatttattc gcactcgaat ccttactaaa taaaataaaa agagatcaat
    39301 aatagagctg ttgggaaata aaagcatatt tccggatgac agaacttccc ccatcccgat
    39361 tgaatttatg ctgcatctaa atagaagttc catagccctg cactgaccaa catcaattga
    39421 tcatcaaaat cggtcacacg attcctatat gtgggataaa atttgcagta cagcaggata
    39481 taaaatagtt tttcctctat acttctgagt gtaggcttgc gtccgccccc gggcgcacgt
    39541 ttgcggtttg ctaaggagtt gaacacggtg cgttcatagg tatcagcaaa ctgagataac
    39601 agctcgttga atgcttggcg gttaagtcca gtcattgctc gtagcagtcg ctcttgattc
    39661 aggatgcggt ctaagttcaa cattaatgtc accctacttg tctgcttgat tattatccct
    39721 tattttccaa caactctatt atagcttatc ttattttgga gtttaactac atgaaaatcg
    39781 ctgtaaagac tcctactgag tgaaagtgaa cttctttccc acgtattcga gtagctgttg
    39841 taagctggcc tcgatggaaa gttccgaagt ttccaccagt aaatctggtg ttctcggtgg
    39901 ttcgtaggga gcgctaattc ccgtaaaaga ctcaatttct ccacggcgtg cttttgcata
    39961 gagacccttg gggtcacgtt gttcacaaat ttccatcgga gttgcaatat atacttcatg
    40021 aaacagatct ccggacagaa tacggatttg ctcccggtct ttcctgtaag gtgaaatgaa
    40081 agcagtaatc actaaacaac ccgaatccgc aaaaagtttg gccacctcgc caatacgacg
    40141 aatattttcc gcacgatcag cagcagaaaa tcccaagtca gcacataatc catgacggat
    40201 attgtcacca tcaaggacaa aagtatacca acctttctgg aacaaaatcc gctctaattc
    40261 tagagccaat gttgttttac ctgatcctga taatccagtg aaccatagaa ttccatttcg
    40321 gtgaccattc tttaaacaac gatcaaatgg ggacacaaga tgttttgtat gttgaatatt
    40381 gcttgatttc atatctatga taaatatgat aaaagtgatt ggccaaacag aactgctcac
    40441 ccaataatat agttaaaggt tattttttca aaaactcctt ctaaattata gctcacaatt
    40501 atgcctaaat actttaatac tgctggaccc tgtaaatccg aaatccacta tatgctctct
    40561 cccacagctc gactaccgga tttgaaagca ctaattgacg gagaaaacta ctttataatt
    40621 cacgcgccgc gacaagtcgg caaaactaca gctatgatag ccttagcacg agaattgact
    40681 gatagtggaa aatataccgc agttattctt tccgttgaag tgggatcagt attctcccat
    40741 aatccccagc aagcggagca ggttatttta gaagaatgga aacaggcaat caaattttat
    40801 ttacccaaag aactacaacc atcctattgg ccagagcgtg aaacagactc aggaataggc
    40861 aaaactttaa gtgagtggtc cgcacaatct ccaagacctc ttgtaatctt tttacatgaa
    40921 atcgattccc taacagatga agctttaatc ctaattttaa gacaattacg ctcaggtttt
    40981 ccccgtcgtc ctcggggatt tccccattcg gtggggttaa ttggtatgcg ggatgtgcgg
    41041 gactataagg ttaaatctgg tggaagtgaa cgactgaata cgtcaagtcc tttcaatatc
    41101 aaagcggaat ccttgacttt aagtaatttc actctgtcag aggtggaaga actttactta
    41161 caacatacgc aagctacagg acaaattttt accccggaag caattaaaca agcattttat
    41221 ttaaccgatg ggcaaccatg gttagtaaac gccctagctc gtcaagccac tcaggtgtta
    41281 gtgaaagata ttactcaacc cattaccgct gaagtaatta accaagccaa agaagttctg
    41341 attcagcgcc aggataccca tttggatagt ttggcagagc gcttacggga agatcgggtc
    41401 aaagccatta ttcaacctat gttagctgga tcggacttac cagatacccc agaggatgat
    41461 cgccgtttct tgctagattt aggcttggta aagcgcagtc ccttgggagg actaaccatt
    41521 gccaatccca tttaccagga ggtgattcct cgtgttttgt cccagggtag tcaggatagt
    41581 ctaccccaga ttcaacctac ttggttaaat actgataata ctttaaatcc tgacaaactc
    41641 ttaaatgctt tcctagagtt ttggcgacaa catggggaac cattactcaa aagtgcgcct
    41701 tatcatgaaa ttgctcccca tttagttttg atggcgtttt tacatcgggt agtgaatggt
    41761 ggtggcactt tagaacggga atatgccgtt ggttctggaa gaatggatat ttgtttacgc
    41821 tatggcaagg tagtgatggg catagagtta aaggtttggg ggggaaaatc ggatccgtta
    41881 acgaagggtt tgacccaatt ggataaatat ctgggtgggt taggattaga tagaggttgg
    41941 ttagtaattt ttgatcaccg tccgggatta ccacccatgg gtgagaggat tagtatggaa
    42001 caggccatta gtccagaggg aagaaccatt acagtgattc gtagctagag cgttagatat
    42061 cagatgattg aacctcaatt attgtgcaac gccacatttt ctttccaaag atgtatgtta
    42121 aactctagta aactctaatt aggtcgagaa agagat
//
