LOCUS       BGC0000979              6921 bp    DNA     linear   BCT 25-JUL-2016
DEFINITION  Aphanizomenon sp. 10E9 cylindrospermopsin biosynthesis gene cluster,
            partial sequence.
ACCESSION   BGC0000979
VERSION     BGC0000979
KEYWORDS    .
SOURCE      Aphanizomenon sp. 10E9
  ORGANISM  Aphanizomenon sp. 10E9
            Bacteria; Cyanobacteria; Nostocales; Aphanizomenonaceae;
            Aphanizomenon; unclassified Aphanizomenon.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 21:27:40
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            complement(<1..997)
                     /gene="cyrC"
     CDS             complement(<1..997)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (34-331). E-value:
                     4.1e-124. Score: 406.5. Matches aSDomain:
                     nrpspksdomains_cyrC_PKS_KS.1"
                     /codon_start=1
                     /gene="cyrC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) hyb_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 181.1; E-value:
                     6e-55)"
                     /gene_kind="biosynthetic-additional"
                     /product="polyketide synthase"
                     /protein_id="ADF88260.1"
                     /sec_met_domain="hyb_KS (E-value: 7.7e-135, bitscore:
                     437.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQPNYGILMKNALNEINSLRSQLAAVEAQKNESIAIVGMSCRFP
                     GGATTPERFWVLLREGISAITEIPADRWDVDKYYDADPTSSGKMHTRYGGFLNEVDTFE
                     PSFFNIAAREAVSMDPQQRLLLEVSWEALESGNIVPATLFDSSTGVFIGIGGSNYKSLM
                     IENRSRIGKTDLYELSGTDVSVAAGRISYVLGLMGPSFVIDTACSSSLVSVHQACQSLR
                     QRECDLALAGGVGLLIDPDEMIGLSQGGMLAPDGSCKTFDANANGYVRGEGCGMIVLKR
                     LSDATADGDNILAIIRGSMVNHDGHSSGLTAPRGPAQVSVIKQALDRAGIA"
     source          1..6921
                     /collection_date="2004"
                     /country="Germany"
                     /db_xref="taxon:459665"
                     /mol_type="genomic DNA"
                     /organism="Aphanizomenon sp. 10E9"
                     /strain="10E9"
     misc_feature    <1..>6921
                     /note="cylindrospermopsin biosynthesis gene cluster"
     protocluster    1..6921
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2738:>6921]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2739..>6921
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..6921
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2738:>6921]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2739..>6921
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..6921
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..6921
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000979"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..6921
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     aSDomain        complement(5..895)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrC_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="4.10E-124"
                     /label="cyrC_PKS_KS.1"
                     /locus_tag="cyrC"
                     /protein_end="331"
                     /protein_start="34"
                     /score="406.5"
                     /tool="antismash"
                     /translation="IAIVGMSCRFPGGATTPERFWVLLREGISAITEIPADRWDVDKYY
                     DADPTSSGKMHTRYGGFLNEVDTFEPSFFNIAAREAVSMDPQQRLLLEVSWEALESGNI
                     VPATLFDSSTGVFIGIGGSNYKSLMIENRSRIGKTDLYELSGTDVSVAAGRISYVLGLM
                     GPSFVIDTACSSSLVSVHQACQSLRQRECDLALAGGVGLLIDPDEMIGLSQGGMLAPDG
                     SCKTFDANANGYVRGEGCGMIVLKRLSDATADGDNILAIIRGSMVNHDGHSSGLTAPRG
                     PAQVSVIKQALDRAGI"
     CDS_motif       complement(179..217)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0003"
                     /evalue="1.10E-05"
                     /label="PKSI-KS_m4"
                     /locus_tag="cyrC"
                     /protein_end="273"
                     /protein_start="260"
                     /score="18.0"
                     /tool="antismash"
                     /translation="FDANANGYVRGEG"
     CDS_motif       complement(359..406)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0002"
                     /evalue="3.90E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrC"
                     /protein_end="213"
                     /protein_start="197"
                     /score="21.8"
                     /tool="antismash"
                     /translation="GPSFVIDTACSSSLVS"
     CDS_motif       complement(617..643)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrC_0001"
                     /evalue="3.50E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="cyrC"
                     /protein_end="127"
                     /protein_start="118"
                     /score="10.1"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     gene            1549..2724
                     /gene="cyrA"
     CDS             1549..2724
                     /codon_start=1
                     /gene="cyrA"
                     /product="amidinotransferase"
                     /protein_id="ADF88261.1"
                     /transl_table=11
                     /translation="MQTRIVNSWNEWDELKEMVVGIADGAYFEPTEPGNRPALRDKNIA
                     KMFSFPSGPKKQEVTEKANEELNGLVALLESQGVTVRRPEKHNFGLSVKTPFFEVENQY
                     CAVCPRDVMITFGNEILEATMSRRSRFFEYLPYRKLVYEYWHKDPDMIWNTAPKPTMQN
                     AMYREDFWEWLMEDRFERMHDFEFCVTQDEVIFDAADCSRFGRDIFVQESMTTNRAGIR
                     WLKRHLEPRGFRVHDIHFPLDIFPSHIDCTFVPLAPGVVLVNPDRPIKEGEEKLFMDNG
                     WQFIEAPLPTSTDDEMPMFCQSSKWLAMNVLSISPKKVICEEQEHPLHELLDKHGFEVY
                     LIPFRNVFEFGGSLHCATWDIHRTGTCEDYFPKLNYTPVTASTNGVSRFII"
     gene            2739..>6921
                     /gene="cyrB"
     CDS             2739..>6921
                     /NRPS_PKS="Domain: AMP-binding (28-469). E-value: 5.5e-100.
                     Score: 326.6. Matches aSDomain:
                     nrpspksdomains_cyrB_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (582-649). E-value: 3e-19. Score:
                     60.9. Matches aSDomain: nrpspksdomains_cyrB_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (676-1110). E-value:
                     9.9e-159. Score: 520.6. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1210-1393). E-value: 1.1e-71.
                     Score: 233.5. Matches aSDomain:
                     nrpspksdomains_cyrB_PKS_AT.1"
                     /codon_start=1
                     /gene="cyrB"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     334.9; E-value: 1.1e-101)"
                     /gene_kind="biosynthetic"
                     /product="mixed nonribosomal peptide synthetase/ polyketide
                     synthase"
                     /protein_id="ADF88262.1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-111, bitscore:
                     360.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.9e-14, bitscore:
                     40.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6e-73, bitscore: 233.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 1.2e-170, bitscore:
                     555.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQERESPQILFDGNGTQSEFPDSCIHHLFEDQAAKRPDAIALIDG
                     EQSLTYGELNVRANHLAQHLLSLGCQPDDLLAICIERSAELFIGLLGILKAGCAYVPLD
                     VGYPADRIEYMLRDSDARILLTSTDVAKKLALTIPALQECQTVYLDQEIFEYDFHFLAI
                     AKLLHNQYLRLLHFYFYTLIQQCQATSVSQGIQTQVLPNNLAYCIYTSGSTGNPKGILM
                     EHRSLVNMLWWHQQTRPSVQGVRTLQFCAVSFDFSCHEIFSTLCLGGILVLVPEAVRQN
                     PFALAEFISQQKIEKLFLPVIALLQLSEAVNGNKSTSLALCEVITTGEQMQITPAVANL
                     FQKTGAMLHNHYGATEFQDATTHTLKGNPEGWPTLVPVGRPLHNVQVYILDEAQQPVPL
                     GGEGEFCIGGIGLARGYHNLPDLTNEKFIPNPFGANENAKKLYRTGDLARYLPDGTIEH
                     LGRIDHQVKIRGFRVELGEIESVLASHQAVRECAVVAREIAGHTQLVGYIIAKDTLNLS
                     FDKLEPILRQYSEAVLPEYMIPTRFINISNMPLTPSGKLDRRALPDPKGDRPALSTPLV
                     KPRTQTEKRLAEIWGSYLAVDIVGTHDNFFDLGGTSLLLTQAHKFLCETFNINLSAVSL
                     FQYPTIQTLAQYIDCQGDTTSSDTASRHKKVRKKQSGDSNDIAIISVAGRFPGAETIEQ
                     FWHNLCNGVESITLFSDDELEQTLPELFNNPAYVKAGAVLEGVELFDATFFGYSPKEAA
                     VTDPQQRILLECAWEAFERAGYNPETYPEPVGVYAGSSLSTYLLNNIGSALGIITEQPF
                     IETDMEQFQAKIGNDRSYLATRISYKLNLKGPSVNVQTACSTSLVAVHMACQSLISGEC
                     QMALAGGISVVVPQKGGYLYEEGMVRSQDGHCRAFDAEAQGTIFGNGGGLVLLKRLQDA
                     LDDNDNIMAVIKATAINNDGALKMGYTAPSVDGQADVISEAIAIADIDASTIGYVEAHG
                     TATQLGDPIEVAGLARAFQRSTDSVLGKQQCAIGSVKTNIGHLDEAAGIAGLIKAALAL
                     QYGQIPPSLHYANPNPRIDFDATPFFVNTELREWSRNGYPLRAGVSSFGVGGTNSHIVL
                     EESPVKQPTLFSSLPERSHHLLTLSAHTQEALHELVQRYIQHNETHLDIDLGDLCFTAN
                     TGRKHFEHRLAVVAESIPGLQAQLETAQTAISAQKKNAPPTIAFLFTGQGSQYINMGRT
                     LYDTESTFRAALDRCETILQNLGIESILSVIFGSSEHGLSLDDTAYTQPALFAIEYALY
                     QLWKSWGIQPSVVIGHSVGEYVSACVAGVFSLEDGLKLIAERGRLIQALPRDGSMVSVM
                     ASEKRIADIILPYGGQVGIAAINGPQSVVISGQQQAIDAICAILETEGIKS"
     aSDomain        2823..4145
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_AMP-binding.1"
                     /evalue="5.50E-100"
                     /label="cyrB_AMP-binding.1"
                     /locus_tag="cyrB"
                     /protein_end="469"
                     /protein_start="28"
                     /score="326.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEDQAAKRPDAIALIDGEQSLTYGELNVRANHLAQHLLSLGCQPD
                     DLLAICIERSAELFIGLLGILKAGCAYVPLDVGYPADRIEYMLRDSDARILLTSTDVAK
                     KLALTIPALQECQTVYLDQEIFEYDFHFLAIAKLLHNQYLRLLHFYFYTLIQQCQATSV
                     SQGIQTQVLPNNLAYCIYTSGSTGNPKGILMEHRSLVNMLWWHQQTRPSVQGVRTLQFC
                     AVSFDFSCHEIFSTLCLGGILVLVPEAVRQNPFALAEFISQQKIEKLFLPVIALLQLSE
                     AVNGNKSTSLALCEVITTGEQMQITPAVANLFQKTGAMLHNHYGATEFQDATTHTLKGN
                     PEGWPTLVPVGRPLHNVQVYILDEAQQPVPLGGEGEFCIGGIGLARGYHNLPDLTNEKF
                     IPNPFGANENAKKLYRTGDLARYLPDGTIEHLGRIDHQVKIR"
     aSModule        2823..4685
                     /complete
                     /domains="nrpspksdomains_cyrB_AMP-binding.1"
                     /domains="nrpspksdomains_cyrB_PCP.1"
                     /locus_tags="cyrB"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3009..3050
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0001"
                     /evalue="4.60E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="cyrB"
                     /protein_end="104"
                     /protein_start="90"
                     /score="19.6"
                     /tool="antismash"
                     /translation="LGILKAGCAYVPLD"
     CDS_motif       3351..3410
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0002"
                     /evalue="2.50E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="cyrB"
                     /protein_end="224"
                     /protein_start="204"
                     /score="29.1"
                     /tool="antismash"
                     /translation="AYCIYTSGSTGNPKGILMEH"
     CDS_motif       3666..3686
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0003"
                     /evalue="7.00E+01"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrB"
                     /protein_end="316"
                     /protein_start="309"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="AVNGNKS"
     CDS_motif       3930..4019
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0004"
                     /evalue="5.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="cyrB"
                     /protein_end="427"
                     /protein_start="397"
                     /score="41.1"
                     /tool="antismash"
                     /translation="PLGGEGEFCIGGIGLARGYHNLPDLTNEKF"
     CDS_motif       4110..4175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0005"
                     /evalue="4.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="cyrB"
                     /protein_end="479"
                     /protein_start="457"
                     /score="37.9"
                     /tool="antismash"
                     /translation="HLGRIDHQVKIRGFRVELGEIE"
     aSDomain        4485..4685
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PCP.1"
                     /evalue="3.00E-19"
                     /label="cyrB_PCP.1"
                     /locus_tag="cyrB"
                     /protein_end="649"
                     /protein_start="582"
                     /score="60.9"
                     /tool="antismash"
                     /translation="EKRLAEIWGSYLAVDIVGTHDNFFDLGGTSLLLTQAHKFLCETFN
                     INLSAVSLFQYPTIQTLAQYID"
     aSDomain        4767..6068
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="9.90E-159"
                     /label="cyrB_PKS_KS.1"
                     /locus_tag="cyrB"
                     /protein_end="1110"
                     /protein_start="676"
                     /score="520.6"
                     /tool="antismash"
                     /translation="IAIISVAGRFPGAETIEQFWHNLCNGVESITLFSDDELEQTLPEL
                     FNNPAYVKAGAVLEGVELFDATFFGYSPKEAAVTDPQQRILLECAWEAFERAGYNPETY
                     PEPVGVYAGSSLSTYLLNNIGSALGIITEQPFIETDMEQFQAKIGNDRSYLATRISYKL
                     NLKGPSVNVQTACSTSLVAVHMACQSLISGECQMALAGGISVVVPQKGGYLYEEGMVRS
                     QDGHCRAFDAEAQGTIFGNGGGLVLLKRLQDALDDNDNIMAVIKATAINNDGALKMGYT
                     APSVDGQADVISEAIAIADIDASTIGYVEAHGTATQLGDPIEVAGLARAFQRSTDSVLG
                     KQQCAIGSVKTNIGHLDEAAGIAGLIKAALALQYGQIPPSLHYANPNPRIDFDATPFFV
                     NTELREWSRNGYPLRAGVSSFGVGGTNSHIVLEES"
     aSModule        4767..6917
                     /domains="nrpspksdomains_cyrB_PKS_KS.1"
                     /domains="nrpspksdomains_cyrB_PKS_AT.1"
                     /incomplete
                     /locus_tags="cyrB"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       5265..5312
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0006"
                     /evalue="7.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="cyrB"
                     /protein_end="858"
                     /protein_start="842"
                     /score="18.0"
                     /tool="antismash"
                     /translation="GPSVNVQTACSTSLVA"
     CDS_motif       5688..5735
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0007"
                     /evalue="2.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="cyrB"
                     /protein_end="999"
                     /protein_start="983"
                     /score="13.1"
                     /tool="antismash"
                     /translation="YVEAHGTATQLGDPIE"
     CDS_motif       5805..5849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0008"
                     /evalue="1.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="cyrB"
                     /protein_end="1037"
                     /protein_start="1022"
                     /score="11.1"
                     /tool="antismash"
                     /translation="GSVKTNIGHLDEAAG"
     aSDomain        6369..6917
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cyrB_PKS_AT.1"
                     /evalue="1.10E-71"
                     /label="cyrB_PKS_AT.1"
                     /locus_tag="cyrB"
                     /protein_end="1393"
                     /protein_start="1210"
                     /score="233.5"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYINMGRTLYDTESTFRAALDRCETILQNLGIESILSV
                     IFGSSEHGLSLDDTAYTQPALFAIEYALYQLWKSWGIQPSVVIGHSVGEYVSACVAGVF
                     SLEDGLKLIAERGRLIQALPRDGSMVSVMASEKRIADIILPYGGQVGIAAINGPQSVVI
                     SGQQQAIDAICAILETEGIK"
     CDS_motif       6372..6419
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0009"
                     /evalue="1.20E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="cyrB"
                     /protein_end="1227"
                     /protein_start="1211"
                     /score="20.8"
                     /tool="antismash"
                     /translation="FTGQGSQYINMGRTLY"
     CDS_motif       6543..6605
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0010"
                     /evalue="2.00E-04"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="cyrB"
                     /protein_end="1289"
                     /protein_start="1268"
                     /score="14.5"
                     /tool="antismash"
                     /translation="TAYTQPALFAIEYALYQLWKS"
     CDS_motif       6609..6731
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0011"
                     /evalue="5.00E-27"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="cyrB"
                     /protein_end="1331"
                     /protein_start="1290"
                     /score="86.3"
                     /tool="antismash"
                     /translation="GIQPSVVIGHSVGEYVSACVAGVFSLEDGLKLIAERGRLIQ"
     CDS_motif       6825..6863
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cyrB_0012"
                     /evalue="4.30E-05"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="cyrB"
                     /protein_end="1375"
                     /protein_start="1362"
                     /score="16.6"
                     /tool="antismash"
                     /translation="AAINGPQSVVISG"
ORIGIN
        1 gtgcaatacc tgctctatct aaggcttgct taatgacaga gacttgtgcg gggcctcttg
       61 gagcagttaa accactgcta tgaccatcat gattaaccat agacccacga atgatggcaa
      121 gaatattatc cccatcggct gttgcatccg agagacgttt tagaacaatc atcccacaac
      181 cttcgcctcg cacatagccg tttgcattgg catcaaatgt tttacaacta ccatcaggtg
      241 ccagcatccc cccttgagaa agaccaatca tctcatctgg atcaatgagt aaaccgactc
      301 caccagctag tgctagatca cattctctct gacgcagact ctgacaggct tgatgaactg
      361 agaccaaaga agatgaacaa gctgtatcaa tcacaaaact gggacccatc aaacccagga
      421 cataggatat cctgccggca gcaacactca catcagtgcc acttaactca tacaaatcgg
      481 ttttcccaat ccgactcctg ttttcgatca ttaaagattt gtagttgcta ccaccaatac
      541 cgataaatac accagtggaa ctatcaaaaa gagttgcagg aacaatatta ccggattcca
      601 gagcttccca actgacttca agtagcaagc gttgctgtgg atccatgcta acggcttcac
      661 gggcagcaat attaaagaat gatggctcaa atgtatcaac ttcattcaga aaaccgccgt
      721 aacgagtatg cattttaccg gacgatgtgg ggtcagcatc ataatattta tcaacatccc
      781 agcgatcagc agggatttct gtaatggctg atataccctc gcgcagtaat acccaaaaac
      841 gctctggagt agttgcaccg cctggaaaac ggcaactcat accaacaatg gcaatagact
      901 catttttttg ggcttctacc gcagctagtt gcgatcgtag gctatttatt tcgttcaacg
      961 catttttcat caaaatgcca taattgggct gactcatctt tgattatcct gaataattca
     1021 ccaaaagagc agaaaagagc ctaaaaccaa gtaaaattag gctatacaaa aatttaacta
     1081 ttacgcggta agtcccttat caaaaataag atatcagact taggattaga acactttact
     1141 gttgtcactg atggcgaaaa tatttcggtt ctaccgctcc ccttgtgatc aaataccccc
     1201 ttttatgtgt gcataaccat tgctgtatat gggtttgatc taaattaata ggcgatcgcc
     1261 tatttttgaa aaaattaaac cctcaaatcc attcagtgta agagttttag gtatatttta
     1321 ccgaaaatat cataaaggga gcggtagagc caatatttct aaagatgaga attgctgtga
     1381 taatcctaaa caccttacca agcatgagaa aaaccttaaa cccaagcaga aaaaattagc
     1441 ccgtaaaaaa aagggaagta aatcaaggaa atgtagggta atatattttt cacaagttta
     1501 tcaattgtaa tctactgaat caagtagatt aattaaggtg ttgaagagat gcaaacaaga
     1561 attgtaaata gctggaatga gtgggatgaa ctaaaggaga tggttgtcgg gattgcagat
     1621 ggtgcttatt ttgaaccaac tgagccaggt aaccgccctg ctttacgcga taagaacatt
     1681 gccaaaatgt tctcttttcc cagtggtccg aaaaagcaag aggtaacaga gaaagctaat
     1741 gaggagttga atgggctggt agcgcttcta gaatcacagg gcgtaactgt acgccgccca
     1801 gagaaacata actttggcct gtctgtgaag acaccattct ttgaggtaga gaatcaatat
     1861 tgtgcggtct gcccacgtga tgttatgatc acctttggga acgaaattct cgaagcaact
     1921 atgtcacggc ggtcacgctt ctttgagtat ttaccctatc gcaaactagt ctatgaatat
     1981 tggcataaag atccagatat gatctggaat actgcgccta aaccgactat gcaaaatgcc
     2041 atgtaccgcg aagatttctg ggagtggctg atggaagatc gatttgagcg tatgcatgat
     2101 tttgagttct gcgtcaccca ggatgaggtg atttttgatg cagcagactg tagccgcttt
     2161 ggccgtgata tttttgtgca ggagtcaatg acgactaatc gtgcagggat tcgctggctc
     2221 aaacggcatt tagagccgcg tggcttccgc gtgcatgata ttcacttccc actagatatt
     2281 ttcccatccc acattgattg tacttttgtc cccttagcac ctggggttgt gttagtgaat
     2341 ccagatcgcc ccatcaaaga gggtgaagag aaactcttca tggataacgg ttggcaattc
     2401 atcgaagcac ccctccccac ttccaccgac gatgagatgc ctatgttctg ccagtccagt
     2461 aagtggttgg cgatgaatgt gttaagcatt tcccccaaga aggtcatctg tgaagagcaa
     2521 gagcatccgc ttcatgagtt gctagataaa cacggctttg aggtctatct aattcccttt
     2581 cgcaatgtct ttgagtttgg cggttcgctc cattgtgcca cctgggatat ccatcgcacg
     2641 ggaacctgtg aggattactt ccctaaacta aactatacgc cggtaactgc atcaaccaat
     2701 ggcgtttctc gcttcatcat ttagtaggtt ttatagttat gcaagagaga gaaagcccac
     2761 agatactatt tgatgggaat ggaacacaat ctgagtttcc agatagttgc attcaccact
     2821 tgttcgagga tcaagccgca aagcgaccgg atgcgatcgc tctcattgac ggtgagcaat
     2881 cccttaccta cggggaacta aatgtacgcg ctaaccacct agcccagcat ctcttgtccc
     2941 taggctgtca acccgatgac ctcctcgcca tctgcatcga gcgttcggca gaactcttta
     3001 ttggtttgtt gggtatccta aaagccggat gtgcctatgt gcctttggat gtaggctatc
     3061 ctgccgatcg catagagtat atgttgcggg actcggatgc gcgtatttta ctaacctcaa
     3121 cggatgtcgc taagaaactt gccttaacca tacctgcatt gcaagagtgc caaaccgtct
     3181 atttagatca agagatattt gagtatgatt ttcatttttt agcgatagct aaactattac
     3241 ataaccaata cttgagatta ttacattttt atttttatac cttgattcag caatgccagg
     3301 caacttcggt ttcccaaggg attcagacac aggttctccc caataatctc gcttactgca
     3361 tttacacctc tggctctacc ggaaatccca aagggatctt gatggaacat cgctcactgg
     3421 tgaatatgct ttggtggcat cagcaaacgc ggccttcggt tcagggtgtt aggacgctgc
     3481 aattttgtgc agtcagcttt gacttttcct gccatgaaat tttttctacc ctctgtcttg
     3541 gcgggatatt ggtcttggtg ccagaggcag tgcgccaaaa tccctttgca ttggctgagt
     3601 tcatcagtca acagaaaatt gaaaaattgt ttcttcccgt tatagcatta ctacagttgt
     3661 ccgaagctgt gaatgggaat aaaagcacct ccctcgcgct ttgcgaagtt atcactaccg
     3721 gggagcagat gcagatcaca cctgctgtcg ccaacctctt tcagaaaacc ggggcgatgt
     3781 tgcataatca ctacggggca acggaatttc aagatgccac cactcatacc ctcaagggca
     3841 atccagaggg ctggccaaca ctggtgccag tgggtcgtcc actgcacaat gttcaagtgt
     3901 atattctgga tgaggcacag caacctgtac ctcttggtgg agagggtgaa ttctgtattg
     3961 gtggtattgg actggctcgt ggctatcaca atttgcctga cctaacgaat gaaaaattta
     4021 ttcccaatcc atttggggct aatgagaacg ctaaaaaact ctaccgcaca ggggacttgg
     4081 cacgctacct acccgacggc acgattgagc atttaggacg gatagaccac caggttaaga
     4141 tccgaggttt ccgcgtggaa ttgggggaaa ttgagtccgt gctggcaagt caccaagctg
     4201 tgcgtgaatg tgccgttgtg gcacgggaga ttgcaggtca tacacagttg gtagggtata
     4261 tcatagcaaa ggatacactt aatctcagtt tcgacaaact tgaacctatc ctgcgtcaat
     4321 attcggaagc ggtgctgcca gaatacatga tacccactcg gttcatcaat atcagtaata
     4381 tgccgttgac tcccagtggt aaacttgacc gcagggcatt acctgatccc aaaggcgatc
     4441 gccctgcatt gtctacccca cttgtcaagc ctcgtaccca gacagagaaa cgtttagcag
     4501 agatttgggg cagttatctt gctgtagata ttgtgggaac ccacgacaat ttctttgatc
     4561 taggcggtac gtcactgcta ttgactcaag cgcacaaatt cctgtgcgag acctttaata
     4621 ttaatttgtc cgctgtctca ctctttcaat atcccacaat tcagacattg gcacaatata
     4681 ttgattgcca aggagacaca acctcaagcg atacagcatc caggcacaag aaagtacgta
     4741 aaaagcagtc cggtgacagc aacgatattg ccatcatcag tgtggcaggt cgctttccgg
     4801 gtgctgaaac gattgagcag ttctggcata atctctgtaa tggtgttgaa tccatcaccc
     4861 tttttagtga tgatgagcta gagcagactt tgcctgagtt atttaataat cccgcttatg
     4921 tcaaagcagg tgcggtgcta gaaggcgttg aattatttga tgctaccttt tttggctaca
     4981 gccccaaaga agctgcggtg acagaccctc agcaacggat tttgctagag tgtgcctggg
     5041 aagcatttga acgggctggc tacaaccccg aaacctatcc agaaccagtt ggtgtttatg
     5101 ctggttcaag cctgagtacc tatctgctta acaatattgg ctctgcttta ggcataatta
     5161 ccgagcaacc ctttattgaa acggatatgg agcagtttca ggctaaaatt ggcaatgacc
     5221 ggagctatct tgctacacgc atctcttaca agctgaatct caagggtcca agcgtcaatg
     5281 tgcagaccgc ctgctcaacc tcgttagttg cggttcacat ggcctgtcag agtctcatta
     5341 gtggagagtg tcaaatggct ttagccggtg gtatttctgt ggttgtacca cagaaggggg
     5401 gctatctcta cgaagaaggc atggttcgtt cccaggatgg tcattgtcgc gcctttgatg
     5461 ccgaagccca agggactata tttggcaatg gcgggggctt ggttttgctt aaacggttgc
     5521 aggatgcact ggacgataac gacaacatta tggcagtcat caaagccaca gccatcaaca
     5581 acgacggtgc gctcaagatg ggctacacag caccgagcgt ggatgggcaa gctgatgtaa
     5641 ttagcgaggc gattgctatc gctgacatag atgcaagcac cattggctat gtagaagctc
     5701 atggcacagc cacccaattg ggtgatccga ttgaagtagc agggttagca cgggcatttc
     5761 agcgtagtac ggacagcgtc cttggtaaac aacaatgcgc tattggatca gttaaaacta
     5821 atattggcca cttagatgag gcggcaggca ttgccggact gataaaggct gctctagctc
     5881 tacaatatgg acagattcca ccgagcttgc actatgccaa tcctaatcca cggattgatt
     5941 ttgacgcaac cccatttttt gtcaacacag aactacgcga atggtcaagg aatggttatc
     6001 ctctgcgggc gggggtgagt tcttttggtg tgggtggaac taacagccat attgtgctgg
     6061 aggagtcgcc tgtaaagcaa cccacattgt tctcttcttt gccagaacgc agtcatcatc
     6121 tgctgacgct ttctgcccat acacaagagg ctttgcatga gttggtgcaa cgctacatcc
     6181 aacataacga gacacacctt gatattgact taggcgacct ctgtttcaca gccaatacgg
     6241 gacgcaagca ttttgagcat cgcctagcgg ttgtagccga atcaatccct ggcttacagg
     6301 cacaactgga aactgcacag actgcgattt cagcacagaa aaaaaatgcc ccgccgacga
     6361 tcgcattcct gtttacaggt caaggctcac aatacattaa catggggcgc accctctacg
     6421 atactgaatc aacattccgt gcagcccttg accgatgtga aaccattctc caaaatttag
     6481 ggatcgagtc cattctctcc gttatttttg gttcatctga gcatggactc tcattagatg
     6541 acacagccta tacccagccc gcactctttg ccatcgaata cgcgctctat caattatgga
     6601 agtcgtgggg catccagccc tcagtggtga taggtcatag tgtaggtgaa tatgtgtccg
     6661 cttgtgtggc gggagtcttt agcttagagg atgggttgaa actgattgca gaacgaggac
     6721 gactgataca ggcacttcct cgtgatggga gcatggtttc cgtgatggca agcgagaagc
     6781 gtattgcaga tatcatttta ccttatgggg gacaggtagg gatcgccgcg attaatggac
     6841 cacaaagtgt tgtaatttct gggcaacagc aagcgattga tgctatttgt gccatcttgg
     6901 aaactgaggg catcaaaagc a
//
