LOCUS       BGC0001006             25045 bp    DNA     linear   BCT 28-JAN-2014
DEFINITION  Salinispora tropica CNB-440, complete genome.
ACCESSION   BGC0001006
VERSION     BGC0001006
KEYWORDS    .
SOURCE      Salinispora tropica CNB-440
  ORGANISM  Salinispora tropica CNB-440
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Salinispora.
COMMENT     URL -- http://www.jgi.doe.gov
            JGI Project ID: 4001585
            Source DNA and bacteria available from Paul Jensen
            (pjensen@ucsd.edu)
            Contacts: Paul Jensen (pjensen@ucsd.edu)
            Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 21:50:35
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..858
                     /NRPS_PKS="Domain: oMT (41-153). E-value: 1.3e-07. Score:
                     21.8. Matches aSDomain: nrpspksdomains_Strop_3055_oMT.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR003333"
                     /db_xref="InterPro:IPR007848"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 94.1; E-value:
                     1.6e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Strop_3055"
                     /note="PFAM: Cyclopropane-fatty-acyl-phospholipid synthase;
                     methyltransferase small; Methyltransferase type 11;
                     Methyltransferase type 12"
                     /product="Methyltransferase type 11"
                     /protein_id="ABP55492.1"
                     /sec_met_domain="PCMT (E-value: 5.3e-14, bitscore: 42.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQTDLTARVRDAYDKSADQYDSAGQLLFHPLGKTVADLLELKP
                     GERVLDLGCGRGACLFPIAAQVGTEGFVLGIDQAPGMVEACGADLEARGLADRAQVRLG
                     DVQSFTVDRPFDAISAGMVLFLLPAPQQALAAAAAALRSGGRLVATTFPTENGRLAAGW
                     ESAEILAEVLSTYLPEGVDDPWQLVLGLNGPLVSEESTASAVLTAGFTDVDIRHIAAKS
                     RFESIDDYLAWTWTVTPRMLWELVPPERRTEATNAARTALRSLAGSDGSLVFSCPTRTI
                     RAVR"
     protocluster    1..25045
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[968:8099]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      969..8099
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..25045
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[968:8099]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      969..8099
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..25045
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="chemical_hybrid"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     subregion       1..25045
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001006"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25045
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..858
                     /locus_tag="Strop_3055"
     aSDomain        124..459
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3055_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="1.30E-07"
                     /label="Strop_3055_oMT.1"
                     /locus_tag="Strop_3055"
                     /protein_end="153"
                     /protein_start="41"
                     /score="21.8"
                     /tool="antismash"
                     /translation="ELKPGERVLDLGCGRGACLFPIAAQVGTEGFVLGIDQAPGMVEAC
                     GADLEARGLADRAQVRLGDVQSFTVDRPFDAISAGMVLFLLPAPQQALAAAAAALRSGG
                     RLVATTFP"
     gene            969..8099
                     /locus_tag="Strop_3056"
     CDS             969..8099
                     /NRPS_PKS="Domain: CAL_domain (33-444). E-value: 7.5e-166.
                     Score: 544.8. Matches aSDomain:
                     nrpspksdomains_Strop_3056_CAL_domain.1"
                     /NRPS_PKS="Domain: ACP (552-624). E-value: 1.7e-26. Score:
                     84.2. Matches aSDomain: nrpspksdomains_Strop_3056_ACP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (646-1070). E-value:
                     4.1e-177. Score: 581.1. Matches aSDomain:
                     nrpspksdomains_Strop_3056_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1177-1470). E-value: 2.8e-109.
                     Score: 356.9. Matches aSDomain:
                     nrpspksdomains_Strop_3056_PKS_AT.1"
                     /NRPS_PKS="Domain: ACP (1592-1663). E-value: 5.4e-27.
                     Score: 85.8. Matches aSDomain:
                     nrpspksdomains_Strop_3056_ACP.2"
                     /NRPS_PKS="Domain: TD (1702-1942). E-value: 6e-89. Score:
                     289.3. Matches aSDomain: nrpspksdomains_Strop_3056_TD.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR000182"
                     /db_xref="InterPro:IPR000794"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR001227"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002016"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR010080"
                     /db_xref="InterPro:IPR013120"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 283.2; E-value:
                     6.1e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="Strop_3056"
                     /note="TIGRFAM: thioester reductase domain; PFAM:
                     GCN5-related N-acetyltransferase; beta-ketoacyl synthase;
                     AMP-dependent synthetase and ligase; acyl transferase
                     domain protein; NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase;
                     phosphopantetheine-binding; Male sterility C-terminal
                     domain"
                     /product="thioester reductase domain"
                     /protein_id="ABP55493.1"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-107, bitscore:
                     349.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-20, bitscore:
                     62.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6e-110, bitscore: 356.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 1.1e-216, bitscore:
                     709.3, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.3e-67, bitscore:
                     216.4, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSELIRPLSELLGEHAVRRGDKIAFADGKRGVSYADLDRRTARL
                     AGHLAALGLETGGRAVILMGNSVEAVESSLAVIRAGGIAVPLNPQSSTAEIDHLLDDAE
                     PTVIVCDPARFGQVVRRHHPGRPPRVIRTGEAEAEEDAAAETVRYEELMGTEPSGPAPD
                     EAALDAPAWMLYTSGTTGRPKGVLYSLRSSLWLVAAGHEPVLGLSEQDRLLWPMPLFHG
                     LGQNLCVLGVTAVGASARLMSGFAPSEVRDLLREEAITFLAGVPTTYHYLLDQVTDATT
                     DLSALRLGFVAGSASGAALGSRFEEAFGVPLVDQYGSSETGAITSNRPFGERVPGSVGP
                     PLPGVDIRLVDPDTGQDVPTGKEGEVWVAGPNLMLGYHGQPDATAAVLRDGWYRTGDLG
                     RRDALGHLTLTGRRKELIIRGGENIHPVEVEEVLRTAAGVADVAVGAEPHDVLGEVPVA
                     YLVPGPEGVDAATVFAHCRRLLSFFKVPDRLYTIERVPRTSTGKITRHLLAEADPQLLG
                     VATPDGEAGEAAPIDGTAWAAQLRELPPSERTRSVLELVRSEVARAVGLDSAEQIRPDQ
                     PFVDLGLGSLAVVGVGQRLCARVGLRLPATVVFDHPTPTALAARLVAEVSGTRAPAEGT
                     HAPDRAGADEPIAIVAMACRFPGEVEDPDQLWAMIAEGRDATSELPDDRNWPLDTLIDP
                     NPDHLGTSYVSRGGFISDPAGFDAAFFGISPREATAMDPQQRVLLEIAWEAFERAGIDP
                     TRVAGSPTGLFIGTKGQTYSSLAAPASEYEGYLGFATSGSVLSGRVAYTLGLEGPAITV
                     DTACSASLVALHLACQSLHAGESRLALAGGVTVMATPDDLITFSRQRGLAVDGRVKAFA
                     AAADGTAFGEGAGVVLLERLSDARRAGRKVLAVIRGSAVNQDGTSNGLTAPNGQAQQRL
                     IRQALAAARLGPADIDLVEAHGTGTALGDPIEAEAILATYGQGRAPEQPVWLGSVKSNI
                     THTQAAAGTAGLIKIVQAMRHRTLPATLNVDQPSPHVDWTSGQVRLATEPRPWQVAGRP
                     RRAGVSAFGISGTNAHVIVEESPVEPPVSASVDESRSPAAVPWLLSARSPVALRTQAAR
                     LASMTRSAPELSPAAVGRALARSRAGLDHRATVVGTETKQLLAGLEALASGTPAAGLTT
                     ARAVPDRAVAVLFTGQGAQYPGMGRHLYDSFDVFAAALDEVCQFLAPEVRPALLAPAGT
                     PDDESIHQTGLAQPALFALGVAQFALLRSWGVHPSVLAGHSIGEITAAHVAGVLSLPDA
                     ARLVNARGALMQALPPGGAMLAVKATEEEILPLLSGEESRIGIAAINATRSVVVSGDEE
                     AVTSLATRLAEHGHRATRLRVSHAFHSAHMDPVLDDFRAVAESLAYQRPTIPIVSTMTG
                     VAAGAELLTPGYWVEQLRQPVRFAPAVRAIRTQGTDTFVELGPDGVLTALVRETLGADE
                     HHAVPFCRRGRSGAEAAALGALHALGVPVEWEGFFPPTDEPEVDLPTYPFQRRRYWLPP
                     TAVPSPTRPGPALRERVGGADSSRLGAATERSTGTVPSAGATPAVDAAQLAGAMLAARL
                     GALDEEEQFLHLVQTVTALVAAVLGHADPDEIDPDASLLDLGFDSLTAVELRNQIRDLS
                     GVNLPASLVFEFPTVAVLADHLLSRVLRAADDDEDRVDFAAEVTLAADIVCADEVITAV
                     TEPREVLLTGATGFLGAFLLRDLMRSTNAVVHCLVRSTDEKPAPDRLRDNLQWYQLWDE
                     IDPNRLSVVVGDLAAPRFGLSEQRYDELSRRVDTVYHAAATVNGLYPYSSLKATNVTGT
                     EEILRLAARHRSVPVHHVSSTGVFSAEVVPGVALKSTDPPGPAAALSSGYRQTKLVAEQ
                     IIEIARERGLPVSIYRVDEISGDSEQGRCQTHDFVWLSMKGILQAEAVPTDPAGIFHLV
                     PVDYVSSAILRLSRNANAVNHNHHLANSTHLPFAEMTDALRARGYRLDELGWDTWVRRV
                     RSNPENTMVAMVDSFESTIYSGRNHYLTVDTSETRALLAGSGVDCPAMTRDLFEKYVDF
                     FVRVGYFPPPGGHQTTGSAGGRLHIRPATTADLPRLAQICYEAFEATNTALGLPPEWSS
                     EQAVLEMLQGRLASPSCVSEVAVDATGSVVGSNFLVLGEEVAAFGPLSVAPETQGGGVG
                     RMLMESIVAASNRLGCSSVRAVQVTNNTSAYRLYSSLGFVPQEQLSLMVGYVPPTPGNL
                     AGFEVRPMTEADVAGCQTLYRKINGHSRDSEIHMAAKRAFDWSMPYVVLDKTNGELCGY
                     TTGLADLGHLAATSEAAAWALYAGAGELMRRQDPHGLAPRLRIPGRLAPELLSWAARTR
                     GVSLLRLETLISLGGYTPPEGGVSCPGLSY"
     aSDomain        1068..2300
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_CAL_domain.1"
                     /evalue="7.50E-166"
                     /label="Strop_3056_CAL_domain.1"
                     /locus_tag="Strop_3056"
                     /protein_end="444"
                     /protein_start="33"
                     /score="544.8"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="SYADLDRRTARLAGHLAALGLETGGRAVILMGNSVEAVESSLAVI
                     RAGGIAVPLNPQSSTAEIDHLLDDAEPTVIVCDPARFGQVVRRHHPGRPPRVIRTGEAE
                     AEEDAAAETVRYEELMGTEPSGPAPDEAALDAPAWMLYTSGTTGRPKGVLYSLRSSLWL
                     VAAGHEPVLGLSEQDRLLWPMPLFHGLGQNLCVLGVTAVGASARLMSGFAPSEVRDLLR
                     EEAITFLAGVPTTYHYLLDQVTDATTDLSALRLGFVAGSASGAALGSRFEEAFGVPLVD
                     QYGSSETGAITSNRPFGERVPGSVGPPLPGVDIRLVDPDTGQDVPTGKEGEVWVAGPNL
                     MLGYHGQPDATAAVLRDGWYRTGDLGRRDALGHLTLTGRRKELIIRGGENIHPVEVEEV
                     LRTAAGVADVAV"
     aSModule        1068..2840
                     /domains="nrpspksdomains_Strop_3056_CAL_domain.1"
                     /domains="nrpspksdomains_Strop_3056_ACP.1"
                     /incomplete
                     /locus_tags="Strop_3056"
                     /starter_module
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       1479..1529
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0001"
                     /evalue="3.20E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="Strop_3056"
                     /protein_end="187"
                     /protein_start="170"
                     /score="19.8"
                     /tool="antismash"
                     /translation="AWMLYTSGTTGRPKGVL"
     CDS_motif       2043..2126
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0002"
                     /evalue="2.30E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="Strop_3056"
                     /protein_end="386"
                     /protein_start="358"
                     /score="29.6"
                     /tool="antismash"
                     /translation="PTGKEGEVWVAGPNLMLGYHGQPDATAA"
     CDS_motif       2574..2594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0003"
                     /evalue="8.90E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="Strop_3056"
                     /protein_end="542"
                     /protein_start="535"
                     /score="-2.5"
                     /tool="antismash"
                     /translation="WAAQLRE"
     aSDomain        2625..2840
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_ACP.1"
                     /evalue="1.70E-26"
                     /label="Strop_3056_ACP.1"
                     /locus_tag="Strop_3056"
                     /protein_end="624"
                     /protein_start="552"
                     /score="84.2"
                     /tool="antismash"
                     /translation="LELVRSEVARAVGLDSAEQIRPDQPFVDLGLGSLAVVGVGQRLCA
                     RVGLRLPATVVFDHPTPTALAARLVAE"
     aSDomain        2907..4178
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_PKS_KS.1"
                     /domain_subtype="Modular-KS"
                     /evalue="4.10E-177"
                     /label="Strop_3056_PKS_KS.1"
                     /locus_tag="Strop_3056"
                     /protein_end="1070"
                     /protein_start="646"
                     /score="581.1"
                     /tool="antismash"
                     /translation="IAIVAMACRFPGEVEDPDQLWAMIAEGRDATSELPDDRNWPLDTL
                     IDPNPDHLGTSYVSRGGFISDPAGFDAAFFGISPREATAMDPQQRVLLEIAWEAFERAG
                     IDPTRVAGSPTGLFIGTKGQTYSSLAAPASEYEGYLGFATSGSVLSGRVAYTLGLEGPA
                     ITVDTACSASLVALHLACQSLHAGESRLALAGGVTVMATPDDLITFSRQRGLAVDGRVK
                     AFAAAADGTAFGEGAGVVLLERLSDARRAGRKVLAVIRGSAVNQDGTSNGLTAPNGQAQ
                     QRLIRQALAAARLGPADIDLVEAHGTGTALGDPIEAEAILATYGQGRAPEQPVWLGSVK
                     SNITHTQAAAGTAGLIKIVQAMRHRTLPATLNVDQPSPHVDWTSGQVRLATEPRPWQVA
                     GRPRRAGVSAFGISGTNAHVIVEES"
     aSModule        2907..6794
                     /complete
                     /domains="nrpspksdomains_Strop_3056_PKS_KS.1"
                     /domains="nrpspksdomains_Strop_3056_PKS_AT.1"
                     /domains="nrpspksdomains_Strop_3056_ACP.2"
                     /domains="nrpspksdomains_Strop_3056_TD.1"
                     /final_module
                     /locus_tags="Strop_3056"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       3387..3434
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0004"
                     /evalue="8.10E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="Strop_3056"
                     /protein_end="822"
                     /protein_start="806"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPAITVDTACSASLVA"
     CDS_motif       3810..3854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0005"
                     /evalue="5.60E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="Strop_3056"
                     /protein_end="962"
                     /protein_start="947"
                     /score="12.2"
                     /tool="antismash"
                     /translation="VEAHGTGTALGDPIE"
     aSDomain        4500..5378
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_PKS_AT.1"
                     /evalue="2.80E-109"
                     /label="Strop_3056_PKS_AT.1"
                     /locus_tag="Strop_3056"
                     /protein_end="1470"
                     /protein_start="1177"
                     /score="356.9"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQYPGMGRHLYDSFDVFAAALDEVCQFLAPEVRPALLAP
                     AGTPDDESIHQTGLAQPALFALGVAQFALLRSWGVHPSVLAGHSIGEITAAHVAGVLSL
                     PDAARLVNARGALMQALPPGGAMLAVKATEEEILPLLSGEESRIGIAAINATRSVVVSG
                     DEEAVTSLATRLAEHGHRATRLRVSHAFHSAHMDPVLDDFRAVAESLAYQRPTIPIVST
                     MTGVAAGAELLTPGYWVEQLRQPVRFAPAVRAIRTQGTDTFVELGPDGVLTALVRETLG
                     ADEHHAVPFCRR"
     CDS_motif       4503..4550
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0006"
                     /evalue="1.80E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="Strop_3056"
                     /protein_end="1194"
                     /protein_start="1178"
                     /score="20.2"
                     /tool="antismash"
                     /translation="FTGQGAQYPGMGRHLY"
     CDS_motif       4734..4856
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0007"
                     /evalue="1.00E-20"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="Strop_3056"
                     /protein_end="1296"
                     /protein_start="1255"
                     /score="65.9"
                     /tool="antismash"
                     /translation="GVHPSVLAGHSIGEITAAHVAGVLSLPDAARLVNARGALMQ"
     CDS_motif       4950..4988
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0008"
                     /evalue="8.70E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="Strop_3056"
                     /protein_end="1340"
                     /protein_start="1327"
                     /score="9.5"
                     /tool="antismash"
                     /translation="AAINATRSVVVSG"
     CDS_motif       5208..5243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_Strop_3056_0009"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="Strop_3056"
                     /protein_end="1425"
                     /protein_start="1413"
                     /score="15.6"
                     /tool="antismash"
                     /translation="YWVEQLRQPVRF"
     aSDomain        5745..5957
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_ACP.2"
                     /evalue="5.40E-27"
                     /label="Strop_3056_ACP.2"
                     /locus_tag="Strop_3056"
                     /protein_end="1663"
                     /protein_start="1592"
                     /score="85.8"
                     /tool="antismash"
                     /translation="QTVTALVAAVLGHADPDEIDPDASLLDLGFDSLTAVELRNQIRDL
                     SGVNLPASLVFEFPTVAVLADHLLSR"
     aSDomain        6075..6794
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Strop_3056_TD.1"
                     /evalue="6.00E-89"
                     /label="Strop_3056_TD.1"
                     /locus_tag="Strop_3056"
                     /protein_end="1942"
                     /protein_start="1702"
                     /score="289.3"
                     /tool="antismash"
                     /translation="VLLTGATGFLGAFLLRDLMRSTNAVVHCLVRSTDEKPAPDRLRDN
                     LQWYQLWDEIDPNRLSVVVGDLAAPRFGLSEQRYDELSRRVDTVYHAAATVNGLYPYSS
                     LKATNVTGTEEILRLAARHRSVPVHHVSSTGVFSAEVVPGVALKSTDPPGPAAALSSGY
                     RQTKLVAEQIIEIARERGLPVSIYRVDEISGDSEQGRCQTHDFVWLSMKGILQAEAVPT
                     DPAGIFHLVPVDYVSSAI"
     gene            complement(8226..10187)
                     /locus_tag="Strop_3057"
     CDS             complement(8226..10187)
                     /EC_number="6.3.5.4"
                     /codon_start=1
                     /db_xref="InterPro:IPR000583"
                     /db_xref="InterPro:IPR001962"
                     /db_xref="InterPro:IPR006162"
                     /db_xref="InterPro:IPR006426"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 628; E-value: 2.7e-190)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Strop_3057"
                     /note="TIGRFAM: asparagine synthase
                     (glutamine-hydrolyzing); PFAM: glutamine amidotransferase,
                     class-II; asparagine synthase"
                     /product="asparagine synthase (glutamine-hydrolysing)"
                     /protein_id="ABP55494.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-99, bitscore:
                     323.3, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 5.8e-43, bitscore:
                     135.5, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLLAFFSARGDAAAHRDHIANALECLHHRGPDETGVEVVGDAS
                     GQYADGVFAHKRLAIIDVASSHEPLPYANGRYLLTFNGEIYNYIELREELARDYGAQFA
                     TSGDGEVIVAGYHYWGEQVLTRLRGMFAFVVWDRQERRAFGARDYFGIKPLHYLETADG
                     LYLASEKKALLPFAPANYQGDAGIDTASLSHYLTLQYVPEPGTLHQGVRRIGSGEYLTW
                     TPGGRIDVRRWYRPVFRPAPVPDEQKLYHEIRETLRDSVRIHMRSDVPVGSFLSSGIDS
                     TAVVALAREFNPNILTFTVGYDVPGYSEIDVAQESARHLDVTTIPTKIGPQDMIAALPK
                     IVWHLDDPVADPALVPLYFVARKAAEHVTVVLSGEGADEFFGGYTIYREPLSLSSVNGL
                     PDGVQKGLRAVSKAIPQGVKGKSFLERGTTPIEARYYGNARMFTEEEKQHLLRRYDPSV
                     RYTDITAPIYAECTELDDVTKMQYVDLYTWLRGDILVKADRISMAHSLEVRVPFLDRAV
                     FDVASKIPVDLRLPPRSDATKYAMRQALQGVVPPAIVNRRKLGFPTPTRVWLRGEMYEW
                     ARHMLATSGAGDLIDLPYALRLLDEHKREEADHSRKVWTVLIFCIWHAIFVAKTLDPGI
                     QRNQSALLTKPVVGSMVR"
     gene            10308..11786
                     /locus_tag="Strop_3058"
     CDS             10308..11786
                     /EC_number="3.4.11.9"
                     /codon_start=1
                     /db_xref="InterPro:IPR000994"
                     /db_xref="InterPro:IPR007865"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172:methionine aminopeptidase (Score: 309.7; E-value:
                     4.8e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Strop_3058"
                     /note="PFAM: peptidase M24; peptidase M24B, X-Pro
                     dipeptidase/aminopeptidase domain protein"
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="ABP55495.1"
                     /transl_table=11
                     /translation="MTEEHIHRDPGGTESHDPNFPAALLAFMRQGWRDTALPVVPHPAT
                     PHHAKRRAALSATFPGETLVIPTGGEQVRANDTAHRFRPGSDFAYLTGDHEPDSVLVLR
                     PTVSGHEPLLYLRPHASRQSDEFFRSRHGELWLGRRRTLAEKSSELGLPTADLADLDAA
                     LADLAPARTRVLRGFDSRVDAALRPYDGRRERGQPTRDQELASAISELRLVKDEWEIAQ
                     LQDAVDATVRGFEDVARALPADRGVSERLLEGIFALRARHDGNDIGYGSIVGAAEHATI
                     LHWVHNHGTTRPGDLLLMDMGVENDHLYTADVTRVLPVSGRFTALQRQVYDIVYAAQQA
                     GIEFIRPGVAFKDVHLTCMRVLAEGLAELGLLPVSVDEAMDETSAVYRRWTLHGFGHML
                     GIDVHDCANSRSAMYRDGTLGEGYVLTVEPGLYFQPEDELVPEELRGIGVRIEDDVLVT
                     ANGTVNLSAGLPRTADDVETWLARQREAGPRLPG"
     gene            12068..13639
                     /locus_tag="Strop_3059"
     CDS             12068..13639
                     /codon_start=1
                     /locus_tag="Strop_3059"
                     /product="hypothetical protein"
                     /protein_id="ABP55496.1"
                     /transl_table=11
                     /translation="MSTEITTPDGGANVGPPNRGRQTLWVTAGVVGLTGVVGLAVLGGI
                     AARDDEKAGSAGQAAAPADAGPRVDAAGDTYNESEWSGSERSGQDDRRATEKHREKTVP
                     CSSDKLIQAILHANQNRGGVLTLAKDCTYELTRSKQGNGLPVITEPIVLAGHNTTIARA
                     ATADHFRILNVGRDGHLTLRGVTVKNGRTAPPLPFPTPEAAPLLTLSAPTNTPQPAAPT
                     AAESAATAAAVGPFVGGAGILVQRGGRADIEKSSIRWNQTGHNGGGIANYGTTTIGKSS
                     VESNSAAAFGGGIFNVGVLRIEDSKIEQNDARQGGGGFANGSFRPGVKGGTVWVWKSTI
                     NHNHTQGLAGGILDRSGEMSVTRSQVTENTAGRDAGGVLGVDGSQLYLEQVMLERNVAM
                     GVGGGLAVAADAIAVLQESALKQNVANGAGGGGLFNAQAFVTLRDSQVARNRAVGPFAV
                     GGGIVNAFGQVDLVRSAVTQNAATTPPGGIFTTNDGVDIDRKSAVKQNRPTNCLGSPVV
                     PERCFG"
     sig_peptide     13985..14137
                     /locus_tag="Strop_3060"
                     /note="Signal predicted by SignalP 2.0 HMM (Signal peptide
                     probabilty 0.989) with cleavage site probability 0.808 at
                     residue 51"
     gene            13985..16006
                     /locus_tag="Strop_3060"
     CDS             13985..16006
                     /codon_start=1
                     /db_xref="InterPro:IPR003368"
                     /locus_tag="Strop_3060"
                     /product="hypothetical protein"
                     /protein_id="ABP55497.1"
                     /transl_table=11
                     /translation="MYNYLPKNNATDPEATSKRRRKLWLASGVAGLTGVVSIAAVGLTG
                     VGAGAQDMAWNTAQVTKDGEQSADDREMGREGDWERGREGDWGKGREGDWDSRHGHQGR
                     EKKRGKEVPCKTDKLIQAIIYANNNQGGVLKLAKDCTYTLTRSDGFGNGLPVIEEPIKL
                     IGHNTKIVRDSQAEFFRILNVGRGGQLKVEGLSIKGGKTLEVEQGENTPEAVWARFSNS
                     VAAGEAAQAGQPYLPLLQGEPQAADAEATTPAEAASPRANTETPAEAAQTSQWSNGAAN
                     GNGAAIGNGAANRAAAANGAAAGNENGATDWSGNGAANGAAAANGAAAGNENGATDWSG
                     SGAANGAAAANRAAAGNENGATDWSGNGAANADNAADAANVLQDENLSDGAGVLVQAGG
                     SAEFEKSHVEHNLAGGLGGGIANFGKTSLYHTTVADNHAFQFGGGIFNAGMLKISSSRV
                     KDNGAIIGGGGISNGAALVDGEDTDAGTVRIEKAEITANETLGFGGGLLDIGGDTTITQ
                     SKITSNLALLAGGGIAAVGQSNLYLKETEVAKNTTTGAGGGLALVLGAIVNVDKSKVLD
                     NKAVTFGGGVFNVLSAVTFRNSSVSGNLAAVSGGGIFNVAGAVDLTASKVTKNRSTFEP
                     GGVFSALGEVTVDNKSAIKGNDPTNCQGSVDEIENCFG"
     gene            complement(16073..18913)
                     /locus_tag="Strop_3061"
     CDS             complement(16073..18913)
                     /codon_start=1
                     /db_xref="InterPro:IPR004193"
                     /db_xref="InterPro:IPR006047"
                     /db_xref="InterPro:IPR011839"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297:Pullulanase, type I (Score: 835.7; E-value:
                     9e-253)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Strop_3061"
                     /note="TIGRFAM: alpha-1,6-glucosidase, pullulanase-type;
                     PFAM: glycoside hydrolase, family 13 domain protein; alpha
                     amylase, catalytic region"
                     /product="alpha-1,6-glucosidase, pullulanase-type"
                     /protein_id="ABP55498.1"
                     /sec_met_domain="CBM_48 (E-value: 2.5e-13, bitscore: 39.9,
                     seeds: 59, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPPPIPRKALLTLASLATLTLAGTNTFVHIDPSAGTDVLAMAGT
                     EQWAVDHSATLLTAGEDQSEPGTTTDLDLTRQKAHWIDRGTLAWPTGPPGGTTYALVAA
                     ASGGVTIVDGELAGTYRTVPLRVRHHGLTKAQRERFPHLAAYQALVLDRKHLAGVPAAL
                     RGQLVVTERDTDGTLRVATGVQVPGVLDDIYAPATRARLGPTFAGAVPTLAVWAPTART
                     VTLELFDTPTARPRPVTMSRDDRTGVWSVRGTPSWTGKYYRYRVEAWQPAEQQMVTAAV
                     TDPYSLALAPDSTHSQIVDLADPRLAPPGWTNLRKPAAVPATKAQISELSVRDFSIADS
                     TVPAERRGTFRAFTDPVTAGMRHLKALGDAGTTHLHLLPAFDFATIPERRADQQQPPCD
                     LAALPPDSDEQQRCVAAVADTDGYNWGYDPLHYTVPEGGYAVNPAGAARTTEFRRMVAG
                     VNGAGLRVVLDVVYNHTSATGTDPKSVLDQVVPGYYHRLLADGSVATSTCCANTAPEHA
                     MMGKLVVDSVVTWAKEYKVDGFRFDLMGHHPKANMLAVRAALDELTVARDGVDGRGILL
                     YGEGWNFGEVADGARFVQATQANMAGTGIGTFNDRLRDAVRGGGPFDANPRQQGFASGL
                     FTDPNNDPVNGSTAQQRARLLHQHDLIKVGLSGNLRGYRFTNTAGEQVTGAQVDYNGSP
                     AGYTAAPGESVTYVDAHDNEILYDALAYKLPADTTAVDRARMQVLALGTAVLGQGTGFV
                     TAGTERLRSKSLDRNSYNSGDWFNQIRWECAQGNGFGVGLPPESDNKDKWPYARPLLAD
                     PGLVPGCATMDLAEARFAELLRIRSSSPVFGLRTAEQVQRRVAFPLSGRTEQPGVLTMT
                     LDSRGLGGPWKSVTVIFNATPQPATQQLIDLRGADVTLHPVLRTSADELLRTSSFAADS
                     GTFTVPARSLTVFVQR"
     sig_peptide     complement(18788..18913)
                     /locus_tag="Strop_3061"
                     /note="Signal predicted by SignalP 2.0 HMM (Signal peptide
                     probabilty 0.999) with cleavage site probability 0.485 at
                     residue 42"
     gene            19201..22035
                     /locus_tag="Strop_3062"
     CDS             19201..22035
                     /EC_number="4.2.1.3"
                     /codon_start=1
                     /db_xref="InterPro:IPR000573"
                     /db_xref="InterPro:IPR001030"
                     /db_xref="InterPro:IPR006249"
                     /locus_tag="Strop_3062"
                     /note="TIGRFAM: aconitate hydratase 1; PFAM: aconitate
                     hydratase domain protein"
                     /product="aconitase"
                     /protein_id="ABP55499.1"
                     /transl_table=11
                     /translation="MASLDTFGAKTQLRVGDASYEIFKINKVEGHDRLPYSLKVLLENL
                     LRTEDGANITADHIRQLGAWEPTADPSVEIQFTPSRVLMQDFTGVPCVVDLATMREAVR
                     DLGGDPTKVNPLAPAELVIDHSVIADLFGREDAFQRNVELEYERNKERYQFLRWGQTAF
                     NEFKVVPPGTGIVHQVNIEYLARTVMERNGQAYPDTVVGTDSHTTMVNGLGVLGWGVGG
                     IEAEAAMLGQPVSMLIPRVVGFKLSGEMPAGTTATDLVLTITEMLRKHGVVGKFVEFYG
                     PGVSAVPLANRATIGNMSPEYGSTVAIFPIDAETVRYLELTGRDPQQVALVEAYAKEQG
                     LWHDPAAEPNYSERLELDLGSIEPSLAGPKRPQDRVPLGNAKTLFRAALTDYVATDATG
                     GEQKQGINGPADEASAESFPASDAPANKVIDPADAPRDLVTAAVGSGGRATSPIRVTGA
                     DGTEFELDHGAVVIAAITSCTNTSNPQVMIGAALLARNAVDRGLARKPWVKTTLAPGSK
                     VVMDYYERAGLTPYLEKLGFHLVGYGCTTCIGNSGPLPEEISAAVNEKDLSVVSVLSGN
                     RNFEGRINPDVKMNYLASPPLVVAYALAGTMDIDLANEPIGEDAQGSPVFLRDIWPSSA
                     EIQDVIASAIGAGGFSSAYANVFAGDERWQSLPTPTGNTFAWEGESTYVRKPPYFEGMR
                     REPAPVRDIGAARVLAKLGDSVTTDHISPAGAIKPDSPAGRYLAAHGVPRHEFNSYGSR
                     RGNHEVMIRGTFANIRLRNQLRVPGADSAAGATLPEGGFTVNHLTGEQSTIYDAAVAYQ
                     EAEIPLIVLAGKEYGSGSSRDWAAKGTMLLGVKAVIAESYERIHRSNLIGMGVLPLQFP
                     AGETAESLGLSGVESFAITGVTALNEGDTPRTVRVTTDTGVEFDAVVRIDTPGEADYFR
                     HGGILQYVLRRMIG"
     gene            22162..22443
                     /locus_tag="Strop_3063"
     CDS             22162..22443
                     /codon_start=1
                     /locus_tag="Strop_3063"
                     /product="hypothetical protein"
                     /protein_id="ABP55500.1"
                     /transl_table=11
                     /translation="MISPRCVRLVVMDDKTILKRISELVDEEHQLRAEAQANEEGTDEE
                     SRDRLRDLAESLDQCWDLLRRRRAARSTHGDPEAQGVRPAPEVARYLQ"
     gene            complement(22552..23478)
                     /locus_tag="Strop_3064"
     CDS             complement(22552..23478)
                     /codon_start=1
                     /db_xref="InterPro:IPR000687"
                     /db_xref="InterPro:IPR000719"
                     /locus_tag="Strop_3064"
                     /note="PFAM: protein of unknown function RIO1"
                     /product="protein of unknown function RIO1"
                     /protein_id="ABP55501.1"
                     /transl_table=11
                     /translation="MRDHDSPAPERRTRGRRRFDDDEPHFSKRGRRTGPQPADSDPPPE
                     AQTWSSWDDAVHGPEPYPSWLVTELAATDTELGVLKTGKEADVHLVRRAVPDTDRSCLL
                     AAKRYRDADHRLFHRDAGYLEGRRVRRSREMRAMTRRTAFGRQMIAGQWAAAEFAVLGR
                     LWEIGARYGTITVPYPVQLRGTELMLEFLGDSDERQAAPRLAQLRPTEADLRDLWEQLV
                     EALVVLARVGYAHGDLSPYNLLVHEGHLVLIDLPQVVDVVANPQGPEYLARDVRVVATW
                     FAARGLPAEQAEPLALTEQLLREAGLR"
     gene            complement(23634..24278)
                     /locus_tag="Strop_3065"
     CDS             complement(23634..24278)
                     /codon_start=1
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006439"
                     /locus_tag="Strop_3065"
                     /note="TIGRFAM: HAD-superfamily hydrolase, subfamily IA,
                     variant 1; PFAM: Haloacid dehalogenase domain protein
                     hydrolase"
                     /product="HAD-superfamily hydrolase, subfamily IA, variant
                     1"
                     /protein_id="ABP55502.1"
                     /transl_table=11
                     /translation="MPLLLLDLDNTLLDRENLFRSWGERFLVKIGAPPDDLDWLLSVDA
                     DGLTDRWDVADAIRDRYSLAVRSVDLVEELHEGVLAGTRLDPLVACALQIAGDAGWMPV
                     VVCNGAVRPQEEKIRRTGLDRYLADWVISEAAGVSKPNPRIFALAAQRVRMPLRGAWVV
                     GDGPEADIGGAAAAGLPSVWLHRGRTWTDGRFAPTFTVDGLIAALAAVLAA"
     gene            24473..25045
                     /locus_tag="Strop_3066"
     CDS             24473..25045
                     /codon_start=1
                     /db_xref="InterPro:IPR001647"
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 79.7; E-value: 6.3e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="Strop_3066"
                     /note="PFAM: regulatory protein, TetR"
                     /product="transcriptional regulator, TetR family"
                     /protein_id="ABP55503.1"
                     /transl_table=11
                     /translation="MPRVSQDQLDARRQEILTAARVCFARHGYEGATVRRLEEATGLSR
                     GAIFHHFRDKDSLFLAVAEDDAAAMVETVARNGLVQVMRDLLARAASPDTTGWLGSQLE
                     VSRRLRTDPAFARRWTERSAAIAEATRDRLLRQREAGVLRDDVPIDVLAQFLKLAYDGL
                     VLHLAMGRPADDLGPVLNLVEEAVRRR"
ORIGIN
        1 gtgaccgaac agaccgacct caccgcccga gtccgggacg cctacgacaa gtccgctgac
       61 cagtacgatt ccgccggcca actcctcttc cacccactgg gcaaaacggt cgccgacctg
      121 ctggagctca agccgggcga gcgggtgctc gacctcggct gcggtcgtgg cgcctgcctg
      181 tttccgatcg ccgcccaggt cggtaccgag ggtttcgtgc tcggcatcga ccaggcaccc
      241 ggcatggtgg aggcgtgtgg ggccgacctt gaggcccgcg gactggccga ccgggcgcag
      301 gtgcggctcg gtgacgtcca gagcttcacc gttgaccggc ccttcgacgc gatcagcgcc
      361 ggcatggttc tgttcctgct accggcaccg cagcaggcgt tggccgctgc cgcggcggcg
      421 ctgcgcagcg gtggacggct ggtcgcgacg acctttccga cggagaacgg ccgactcgcc
      481 gccggctggg agtcggcgga gattctcgcc gaggtgttgt ccacctatct cccggagggc
      541 gtcgacgatc catggcagct tgtcctcggt ctcaacggac cgctggtctc cgaggagtca
      601 accgccagcg cggtcctgac ggcgggcttc accgatgtcg acattcgtca catagcagcg
      661 aagtcccgat tcgagtcgat cgacgactac ctcgcctgga cctggacggt caccccgcgc
      721 atgctgtggg aactggtgcc gccggagcgg cggaccgagg ccaccaacgc ggcccggacc
      781 gcgttgcgga gcctggcggg ttccgacggt tcgctggtgt tctcctgccc gacccggacc
      841 attcgcgccg tccgttaacc ggcgccgtcc gttaaccggc gccgtccgct agccgatgtc
      901 gtccgctagc cgacgtcgtc tgcccacacc gacctacccc agagcacgaa gccgaaaggt
      961 acgaagacat gcgtagcgag ttgatccgac cgctgtccga gctgctcggc gaacacgccg
     1021 tccggcgcgg agacaagatc gccttcgccg acggtaagcg tggcgtcagc tacgccgacc
     1081 tcgaccggcg gaccgctcga ctggccggac acctggccgc cctggggttg gagaccggtg
     1141 ggcgagccgt gatcctgatg ggcaacagcg tcgaggcggt ggagagcagc cttgcggtga
     1201 tccgggcggg cggcatcgcg gtaccgctca acccacaatc ctccacggct gagatcgacc
     1261 accttctcga cgatgccgaa ccgacggtca tcgtgtgtga cccggcccgc ttcggccagg
     1321 tggtccggcg gcaccacccg ggtcgaccac cacgggtcat ccgtaccggc gaggccgaag
     1381 ccgaggaaga cgccgcagca gagacggtgc ggtacgagga gttgatgggc accgagccga
     1441 gcggaccggc tcccgacgag gctgcgctgg atgccccggc gtggatgctc tacacgtcgg
     1501 ggaccaccgg tcggccaaag ggggtgctgt actcgctgcg cagttcgttg tggctggtcg
     1561 cggcggggca tgagccggtg ctggggctgt cggagcagga tcgtctgttg tggccgatgc
     1621 cactgttcca cgggctcggg cagaacctgt gcgtgctggg ggtcacggcg gtcggcgcga
     1681 gtgcgcggct gatgagcggc ttcgcaccgt ccgaggtccg cgacctcctg cgcgaggagg
     1741 ccatcacgtt cctggccggg gtgccgacca cctaccacta cctgctggac caggtcaccg
     1801 acgccaccac cgacctctcc gcgctacgac taggtttcgt ggcgggatcg gcgagcggtg
     1861 ccgcgttggg cagccgcttc gaggaggcgt tcggtgttcc cctggtggac cagtacgggt
     1921 cctccgaaac cggtgccatc acctcgaacc ggccgttcgg ggagcgggtc cccggctccg
     1981 tcgggccacc gctccccggc gtggacatcc gcctggtcga ccccgacacc ggccaggacg
     2041 tgcccaccgg gaaggagggc gaggtctggg tcgccggacc gaacctcatg ctcggatacc
     2101 acgggcagcc cgatgccacc gccgctgtcc tgcgcgacgg ctggtaccgc accggtgacc
     2161 ttgggcggcg ggacgccctg gggcacctga ccctgaccgg ccgacgcaag gagctgatca
     2221 tccgtggtgg cgagaacatc caccccgtcg aggtcgagga ggtactgcgt accgccgccg
     2281 gggtagccga cgtggcggtg ggtgccgagc cccacgacgt gctcggtgag gtgccggtgg
     2341 cctatctggt gcccggcccc gaaggcgtgg acgcggcgac ggtcttcgcg cactgccggc
     2401 ggctgctctc cttcttcaag gttcccgaca ggctctacac gatcgaacgc gtcccccgga
     2461 ccagcacggg caagatcacc cggcacctgc tggcagaggc ggacccccaa ctgctgggcg
     2521 tagccacccc ggacggcgag gccggcgagg ccgcgccgat cgacggtacg gcgtgggcag
     2581 cgcagttgcg ggagttgccg ccaagcgagc gcacccggag cgtcctggag ctggttcgca
     2641 gcgaggtagc ccgcgccgtg ggtctcgact ctgccgaaca gatccgaccc gaccagccct
     2701 tcgtcgacct cgggctcggt tccctcgccg tcgtcggggt tggtcagcgg ctctgcgccc
     2761 gagtcgggct acggcttccg gcgaccgtcg tgttcgacca tccgacgccc accgcccttg
     2821 cggcccggct ggtcgccgag gtgagcggaa cgcgtgcgcc ggccgaaggc acccacgctc
     2881 cggaccgggc tggtgccgac gagccgatcg cgatcgtcgc gatggcctgc cgattccccg
     2941 gcgaagtcga ggatccggac caactctggg ccatgatcgc cgaaggacgc gacgccacct
     3001 cagagctgcc ggacgaccgg aactggccgc tggacaccct catcgacccg aacccggacc
     3061 acctcggcac cagctacgta tcccggggcg ggttcatctc cgaccccgcc ggcttcgacg
     3121 ccgccttctt cgggatcagc ccgcgggagg cgaccgcgat ggacccgcag cagcgggtac
     3181 tcctggagat cgcctgggag gcgttcgagc gtgccggaat cgatcccacc cgggtggctg
     3241 gctccccgac cggcctcttc atcggcacga aggggcagac gtacagttcc ctcgccgcgc
     3301 cggcctcgga gtacgagggc tacctgggct tcgccacctc gggcagtgtg ctgtctggac
     3361 gcgtcgccta caccctcggg ttggaaggtc cggccatcac ggtggacacc gcctgctcgg
     3421 cgtcgttggt ggcgctccac ctggcgtgtc agtcgctgca cgccggggag tcccgcctcg
     3481 ccctcgccgg tggggtcacc gtgatggcca cccccgacga tctgatcacg ttcagccgtc
     3541 agcgtggcct cgccgtggat ggccgggtca aggcgttcgc cgcagcagca gacggtaccg
     3601 ccttcggcga aggtgcgggg gtggtgctcc tggagcgcct ctcggacgcg cgccgggcgg
     3661 ggcggaaggt gctcgccgtc atccggggca gcgcggtcaa ccaggacggc acgtcgaacg
     3721 ggctcaccgc ccccaacggc caggcccagc aacggttgat ccgtcaggca ctcgccgccg
     3781 cccggctcgg tcccgccgac atcgacctgg tcgaggcgca cggcacggga accgcgctcg
     3841 gtgaccccat cgaagccgag gcgattctgg ccacctacgg gcaggggcgg gcgccggagc
     3901 aaccggtatg gctcggatca gtcaagtcca acatcaccca cacccaggcg gctgccggca
     3961 ctgccggtct catcaagatc gtgcaggcga tgcgccaccg gactctcccg gccacgctca
     4021 acgttgacca accgtcgccg cacgtcgact ggacctccgg ccaggtacgc ctggcgaccg
     4081 agccccggcc ctggcaggtg gccggccggc cccggcgggc cggggtctcc gccttcggga
     4141 tcagcggcac caatgcgcat gtcatcgtgg aagagagccc ggtcgagccg ccggtgtcgg
     4201 cgagcgttga cgagtcccgg agccccgccg ccgttccctg gctgctctcc gccaggtcgc
     4261 cggtggcgct gcggacgcag gctgcccggc tggcctcgat gacgcgctcc gcgcccgagc
     4321 tcagcccggc ggccgtgggc cgcgcgctgg ctcgctcgcg cgcgggcctg gaccatcggg
     4381 cgaccgtggt gggtacggag accaagcaac tcctggcggg cctggaggcc ctcgcctcgg
     4441 gcacgccggc ggccgggctg acgacggcac gcgcggtgcc cgaccgggcc gtcgctgtgc
     4501 tcttcaccgg ccagggcgcg cagtacccgg gcatgggccg ccacctttac gacagcttcg
     4561 acgtcttcgc cgccgcgctg gacgaggtct gtcagtttct ggcaccggag gtacggccgg
     4621 ccctgctggc gccggccggg acgccggatg acgagtcgat ccaccaaacc ggtctcgccc
     4681 agcccgccct cttcgccctg ggggtcgccc aattcgccct cctgcgctcc tggggggtac
     4741 acccgagcgt gctcgctggg cactccatcg gcgagatcac cgcggcacac gtggccgggg
     4801 tactctcgct gccggatgcg gcccgcctgg tcaatgcccg gggcgccctg atgcaggcgc
     4861 tgcccccggg cggggcgatg ctcgcggtga aggccaccga ggaggagata ctgcccctgc
     4921 tctccgggga ggagtcgcgg atcggaatcg ccgcgatcaa cgcgacccgg tcggtcgtcg
     4981 tctcgggcga cgaagaggcc gtgacctcgc tcgccacccg gctggccgaa cacgggcatc
     5041 gggccacgcg cctccgggtg agccatgcct tccactctgc tcacatggac cccgtcctcg
     5101 acgacttccg cgccgtcgcg gagtcgctgg cctaccagcg acccaccatt ccgatcgtct
     5161 ccaccatgac cggcgtggcc gcaggcgcgg agctgctcac accggggtac tgggtcgagc
     5221 aactccgcca gccggttcgc ttcgcgccag cggtacgcgc aattcgtacg cagggcaccg
     5281 acaccttcgt cgaactcggt cccgacggag tactgaccgc gctggtgcgg gagaccctcg
     5341 gcgcggacga gcaccacgcg gtgccgttct gccgtcgtgg ccggtcgggt gccgaggccg
     5401 ctgccctggg cgccctgcac gccctcggtg tcccggtgga gtgggagggc ttcttcccac
     5461 cgaccgacga acccgaggtc gacctgccca cctacccgtt ccaacgacgg cgctactggc
     5521 tcccacccac cgccgtgccg tcgcccacca ggccgggtcc ggccctccgc gagcgggtcg
     5581 gtggggccga ctcgtcccgc ctcggagcgg ccaccgaacg gtcaacggga accgtgccgt
     5641 cggccggcgc caccccggca gtcgacgccg cgcagttggc gggggccatg ctcgcagctc
     5701 ggctcggtgc cttggacgag gaggagcagt tcctgcacct ggtccagacc gtcacggctc
     5761 tggtcgccgc cgttctcggt cacgcagacc cggacgaaat cgatccagac gcgtccctgc
     5821 tggatctggg cttcgactcc ctcaccgcgg tggagctgcg aaaccagatc cgcgacctca
     5881 gtggggtcaa cctccccgcc tcgctggtct tcgaattccc caccgtggca gtcctcgccg
     5941 atcacctgct gagccgggtg ctccgcgcgg ccgacgacga cgaggaccgg gtggacttcg
     6001 ctgccgaggt aaccctggcc gcggacatcg tctgcgcgga tgaggtcatc accgccgtca
     6061 ccgagcctcg cgaggtcctc ctcaccggag cgaccggctt cctcggcgcc ttcctgctcc
     6121 gcgacctgat gcggagcacg aacgccgtgg tgcactgcct cgtgcggtcc accgacgaga
     6181 agccggcgcc agaccggctg cgggacaacc tccagtggta ccagctctgg gacgagatcg
     6241 atccgaaccg gttgtccgtg gtggtcggcg acctggccgc tccgaggttc ggcctgtcgg
     6301 agcagcggta cgacgagttg tcccgccggg tcgatacggt ctaccacgcg gctgccaccg
     6361 tcaacggtct ctacccctac tcctcgctga aggcaacgaa cgtgaccggc accgaggaga
     6421 tactgcggct ggccgcacgg catcgcagcg ttccggtcca ccacgtgtcg tccacgggcg
     6481 tcttctccgc cgaggtcgta cccggtgtcg ccctgaagtc gaccgacccg ccggggcccg
     6541 ccgcggcgct ctcctccggg taccgacaga ccaaactggt cgcggagcag atcattgaga
     6601 tcgcccggga acgcgggcta ccggtgtcga tctaccgggt cgacgagatc tccggcgact
     6661 cggagcaggg ccgctgccag acgcacgact tcgtgtggct gagcatgaag ggcatcctgc
     6721 aggcggaggc ggttccgacc gacccggccg gcatctttca cctcgtgccc gtcgactacg
     6781 tcagctcggc gatcctgagg ttgtcccgga acgcaaacgc cgtcaaccac aaccatcacc
     6841 tcgccaacag cacacacctg ccgttcgccg agatgacgga cgcactgcgt gcccgcggct
     6901 atcgcctcga cgagttgggc tgggacacct gggtccggcg agtacgctcc aaccccgaga
     6961 acaccatggt ggcgatggtc gacagcttcg agtccaccat ctacagcgga cgcaaccact
     7021 acctgacggt cgacacctcc gagacccgcg cgttgctggc cggtagtggc gtcgactgtc
     7081 cggccatgac ccgggacctg ttcgagaagt acgtcgactt cttcgtccgg gtgggctact
     7141 tcccgccgcc cggcggacac cagacgaccg gctccgcggg tggtcgcctc cacatccggc
     7201 cggcaaccac cgccgacctg ccgcggctgg cccagatctg ctacgaggcg ttcgaggcca
     7261 ccaacaccgc gctgggtcta ccacccgagt ggtcctcgga acaggcggtg ctggagatgc
     7321 tccagggacg actcgcctca ccgagctgtg tgagtgaggt ggcggttgat gcgacgggat
     7381 cggtggtggg ctccaacttc ctggtgctgg gtgaggaggt agccgccttc ggaccgttga
     7441 gcgtcgcccc cgagacacag ggaggcgggg tgggacggat gctgatggag tcgatagtcg
     7501 ccgccagcaa ccggcttggc tgctcctccg tgcgggccgt ccaggtcacc aacaacacgt
     7561 cggcctaccg gctgtactcc tcgctcggct ttgtgccgca ggaacagctc tccctcatgg
     7621 tcgggtacgt cccaccgact cccggcaacc tggcggggtt cgaggtgcgg cccatgaccg
     7681 aggcggatgt tgccggctgc cagacgctgt accgcaagat caacggtcat tcccgggaca
     7741 gcgaaatcca catggcagcc aagcgggcgt tcgactggtc aatgccgtac gtggtgctgg
     7801 acaagaccaa cggggagctc tgcggctaca ccaccggcct ggccgacctg ggtcacctgg
     7861 cggccacgtc agaggcggcg gcgtgggcgc tgtacgccgg cgcgggtgag ctgatgcgcc
     7921 gccaggatcc gcatggcctg gctccccggc tgcgcatccc gggccgcctg gcaccagagc
     7981 tgctcagctg ggccgcccgc acccgcgggg tctcgctgct ccgtctggag acgctgatct
     8041 cgctgggcgg ctacacccca cccgagggcg gggtgtcctg ccccgggctg tcctactgag
     8101 ccgcgcgaaa gcggccatat ccctgcgtga caggcgtcgg ggcggctcgt ggagccgtcc
     8161 cgacgagccc cgacaggccg cccggcgggg aacacccggt gtcgacccga tgctccccgg
     8221 cccgctcaac ggaccatgct gccgacgacc ggcttcgtca gcagggccga ctggttgcgc
     8281 tggatgcccg ggtccagcgt cttggcaacg aagatcgcat gccagatgca gaagatcagg
     8341 accgtccaga ccttgcgcga gtggtcggcc tcctcccgct tgtgctcatc gagcagccgt
     8401 agcgcgtacg gcaggtcgat caggtcaccg gcaccggagg tggccaacat gtgccgggcc
     8461 cactcgtaca tctcaccccg cagccacacc cgggtcgggg tcgggaagcc cagcttccgg
     8521 cgattcacga tggccggcgg gaccacccct tgtagcgcct ggcgcatcgc gtacttggtg
     8581 gcgtcggaac gtgggggcag gcggaggtcg accgggatct tcgacgccac gtcgaagacc
     8641 gcccggtcga ggaagggcac ccgcacctcc agcgagtgcg ccatcgagat ccggtcggcc
     8701 ttgaccagga tgtcgccgcg cagccaggtg tagaggtcca cgtactgcat cttggtgaca
     8761 tcgtcgagtt cggtgcactc ggcatagatc ggggcggtga tgtcggtgta gcgcaccgag
     8821 gggtcgtagc ggcgcagcag gtgctgcttc tcctcctcgg tgaacatccg ggcgttgccg
     8881 tagtagcgcg cctcgatcgg ggtggtgccg cgttccagga agctcttgcc cttgaccccc
     8941 tgcgggatcg ccttcgacac cgcccgcagc cccttctgca cgccgtcggg caggccgttg
     9001 accgagctca gggagagcgg ttcccggtag atggtgtagc cgccgaagaa ctcgtcggca
     9061 ccctcgccgg agagcaccac cgtgacgtgt tcggcggcct tacgcgccac gaagtagagc
     9121 ggcaccagcg ccgggtcggc gaccggatcg tccaggtgcc agacgatctt cggcagcgcc
     9181 gctatcatgt cctgcggccc gatcttggtg ggaatggtgg tgacgtcgag gtggcgggcc
     9241 gactcctggg ccacgtcgat ctccgagtag ccgggcacgt cgtagccgac cgtgaaggtc
     9301 agaatgttcg ggttgaactc ccgggccagc gccaccaccg cggtggagtc gatcccactg
     9361 gacaggaacg aaccgaccgg gacatccgaa cgcatgtgaa tccggacgct gtcccgcagc
     9421 gtctcccgga tctcgtggta gagcttctgc tcatccggca ccggagcggg ccggaacacc
     9481 ggccggtacc accggcggac atcgattcgg ccgcccggcg tccaggtcag gtactccccc
     9541 gagccgatcc gacgaacccc ctggtgcaga gttccgggct ccggcacgta ctgcaacgtc
     9601 agatagtggc tgaggctggc cgtgtcgatg ccggcgtcgc cctggtagtt cgccggtgcg
     9661 aacggcagca gagccttctt ctccgaggcg aggtagaggc cgtcggccgt ctccagatag
     9721 tgcagcggct tgatcccgaa gtagtcgcgg gcaccgaagg cgcgccgctc ctgccggtcc
     9781 cagacaacga aggcgaacat cccccgcagc cgagtgagca cctgctcacc ccagtagtgg
     9841 tagccggcga cgatcacctc accgtcgccg gaggtggcga actgcgcccc gtagtcgcgg
     9901 gccagttcct cccgcagctc gatgtagttg tagatctcgc cgttgaaggt cagcaggtag
     9961 cgcccgttgg cgtagggcag cggctcgtga ctggacgcca catcgatgat cgccagccgc
    10021 ttgtgggcga acacgccatc ggcatactgg ccggacgcgt cgccgacaac ctcaacccca
    10081 gtctcgtccg ggccacgatg gtgcaggcat tccaacgcgt tggcgatgtg gtcgcggtga
    10141 gccgcggcat ccccgcgcgc gctgaagaag gccaggagtc cgcacatggt cgtcatcttt
    10201 tcacgccccc gtcgcggccg tggcggccgt ctgcgcaacc agcctcagcc actggcccgg
    10261 tcacgtcgga taccgtcggg accagcgaca acgcgaaggg agcggagatg accgaggaac
    10321 acatccaccg cgatccgggg ggcacggagt cgcatgatcc aaacttcccg gcggcgctcc
    10381 tggcgttcat gcggcagggc tggcgggaca ccgcgctgcc ggtcgtcccg cacccggcga
    10441 caccccacca cgcgaaacgt cgggctgccc tctccgcgac cttcccgggc gagaccctgg
    10501 tgatccccac cggcggcgag caggtacgcg ccaacgacac cgcccaccga ttccgtccgg
    10561 gaagcgattt cgcgtacctg accggcgacc acgagcccga cagtgtgctc gtgctccgtc
    10621 cgaccgtttc cggacatgag cccctcctct acctgcggcc gcacgcgtcc cggcagagcg
    10681 acgagttctt ccggagtcga cacggcgagc tgtggctcgg ccggcgacgc accctcgcgg
    10741 agaagtcgag cgagttgggc ctgcccaccg ccgacctcgc ggacctggac gccgccctgg
    10801 ccgacctcgc cccggcccga acccgggtgc tgcgcggctt cgactcccgg gttgatgcag
    10861 ccctgcgccc gtacgacggc cggcgggagc ggggacagcc gacccgcgac caggagctgg
    10921 ccagcgcgat ctccgagctg cggctggtca aggacgagtg ggagatcgcc cagctccagg
    10981 acgcggtgga cgccacggta cgcggcttcg aggatgtggc gcgagcactg ccggccgacc
    11041 ggggagtctc cgagcggcta ctcgagggca tcttcgcgct gcgggcccgg cacgacggaa
    11101 acgacatcgg ttacggctcg atcgtcggcg ccgccgagca cgccacaatc ctgcactggg
    11161 tacacaatca cggcaccacc cgcccaggtg acctgctgct gatggacatg ggtgtggaga
    11221 acgaccacct ctacaccgcc gacgtgaccc gggtgctccc ggtgagcggc cggttcaccg
    11281 cgctacagcg tcaggtctac gacatcgtgt acgccgctca gcaggccggc atcgagttca
    11341 tccggccagg cgtggcgttc aaggacgtcc acctgacctg tatgcgggtt ctcgccgagg
    11401 ggctggccga gttgggcctg cttccggtga gcgtggacga ggcgatggac gagacgtcgg
    11461 cggtgtaccg acggtggacc ctgcacggct tcgggcacat gctcggcatc gatgtgcacg
    11521 actgcgcgaa ctcgcgcagt gcgatgtacc gcgacggcac cctgggcgag ggctacgtgc
    11581 tcaccgtgga gccgggcctg tacttccagc ccgaggacga gttggtgccg gaggagctac
    11641 gcggcatcgg cgtccggatc gaggacgacg tcctggtcac ggcgaacggc acggtgaacc
    11701 tctccgccgg gctcccccgg accgctgacg acgtggaaac ctggctggcc aggcagcggg
    11761 aggcaggccc gcgcctgccg ggctgatctc gccgaccgac cccggccgta ccgtttcgtt
    11821 tgggcccgta cggtcccagg cggaaccggt gcggcatttc gccttattgc gacttctatg
    11881 tctgttttgc cctgtcggtg gtactcactc ccacgtgacg caaatcaggt tctttttcgc
    11941 aaacatccac ttccgcgaaa gatcttctca tacggtgagc atcagaggct acaacccgat
    12001 ttgtagcagt ccacaccgcc tttagatggt gtggaccgtc cagtagctga aagggcggaa
    12061 tgctctgatg tccactgaga tcacaactcc tgacggcggg gccaacgtag gcccacccaa
    12121 ccgagggcgg cagacgctct gggtcactgc tggcgtcgtc ggcttgaccg gcgtcgtcgg
    12181 actcgccgtc ctcggcggga tcgccgcccg agacgacgag aaggccggga gcgccggcca
    12241 ggcggcggcc ccagccgacg caggaccacg cgtcgacgcc gccggcgaca cctacaacga
    12301 gagtgagtgg agtggcagcg aacggagcgg tcaggacgac cggcgggcca ccgagaagca
    12361 ccgtgagaag accgtcccgt gcagtagcga caagctgatc caggccatcc tccacgccaa
    12421 ccagaaccgc ggcggcgtgc tgacactcgc caaggactgc acctacgaac tcacccgcag
    12481 caagcagggc aacggcctgc cggtgatcac ggagccgatc gtcctcgcag gccacaacac
    12541 cacaattgcc cgggccgcca ccgccgacca cttccggatt ctcaacgtcg ggcgcgatgg
    12601 tcacctgacc ctccggggag taaccgtcaa gaacggccgg accgcgcccc cgttgccttt
    12661 cccgacgccc gaggcggcac cgctcctcac cctctcggcg ccgacgaaca cgccccagcc
    12721 agccgcacca acggcggccg agtcggcggc gaccgccgca gcggtcggcc cgttcgtcgg
    12781 tggcgcgggg atcttggtcc agcggggcgg tcgggccgac atcgagaaga gctcgatcag
    12841 atggaaccag accggccaca acggcggcgg catcgccaac tacggcacca ccaccatcgg
    12901 gaagtcctcc gtcgagagca acagcgccgc ggccttcggc ggggggatct tcaacgtcgg
    12961 cgttcttcgg atcgaggact cgaagatcga gcagaacgat gcccgccagg ggggtggcgg
    13021 gttcgccaac ggctcgttcc gccccggggt caagggcggc accgtctggg tgtggaagag
    13081 cacaatcaac cacaaccaca cccaaggcct ggccggcggc atcctcgacc gctcgggtga
    13141 gatgagtgtc acccgcagcc aggtcaccga gaacaccgcg ggtcgagacg ccggcggagt
    13201 gcttggcgtc gatggttccc agctgtacct ggagcaggtg atgttggagc ggaatgtcgc
    13261 catgggcgtc gggggtggcc tcgcggtggc cgccgacgcg atcgccgtcc tccaggagag
    13321 cgcgctcaag cagaatgtcg ccaacggcgc ggggggcggc ggcctgttca acgcgcaggc
    13381 cttcgtgacc ctgcgggaca gccaggtcgc ccggaaccga gcagtcggtc catttgcggt
    13441 gggcggcggg atcgtcaacg ccttcggcca ggttgacctg gtgcggagcg cggtgaccca
    13501 gaacgccgcc acgacgccgc cgggcggcat cttcaccacg aacgacggtg tcgacatcga
    13561 ccggaagtcc gcggtcaagc agaaccgacc aacgaactgc ctgggcagcc cggttgttcc
    13621 ggaacgttgc ttcggctgag ttccccctga gagcaccacc acatagagcg ggctcctccg
    13681 accgtcgtac ggccggagga gcccgcacca tcctggcgtc cggaaccgcg ccgtccgcgc
    13741 cgtctgcgat gtgatgccca gaagtcctac tacctgcggg gacctggccc acactggccc
    13801 caagaccgac gctcgtcctg atctagccat ctgcaccgca aatgcggact tttttcgtat
    13861 aagcccgcaa ggtgaggatg attctcatac ggtgtttctg ggagctacaa ccgatttgta
    13921 gtagggacgc tggctttgtg gtgctgcgcc cctgtctggt acgaggagag ggcagagagc
    13981 tccgatgtac aactacctac cgaagaacaa cgcgaccgac ccggaggcga cgtcgaaacg
    14041 acggcgcaag ctctggctcg ccagcggcgt cgccggtctc accggcgtgg tcagcatcgc
    14101 cgcggtcggc cttaccgggg tcggcgccgg cgcccaggac atggcatgga acaccgctca
    14161 ggtcaccaag gacggcgaac agtccgccga cgaccgggag atgggccgcg aaggcgactg
    14221 ggaaaggggc cgcgaaggcg actgggggaa gggccgcgaa ggcgactggg acagccggca
    14281 cggacaccaa ggccgcgaga agaagcgcgg aaaggaggtg ccctgcaaga ccgacaagct
    14341 gatccaggcg atcatctacg ccaacaacaa ccagggtggc gtactcaagc tggccaaaga
    14401 ctgcacctac acgctgaccc gttccgacgg cttcggcaac ggcctgccgg tgatcgagga
    14461 accgatcaag ctcatcggcc acaacaccaa gattgtccgg gacagccagg ccgagttctt
    14521 ccggatcctc aacgtcggtc gcggcggaca gctgaaggtc gagggcctgt ccatcaaggg
    14581 cggcaagacc ctggaagtcg agcagggcga gaacacgccc gaggcagtgt gggcgcgctt
    14641 ctcaaactcg gtcgcggcgg gtgaggcggc ccaggctggc cagccgtacc taccgctgtt
    14701 gcagggcgag ccgcaggcgg cggacgccga ggcaacgacc cccgccgaag cggccagccc
    14761 cagggccaac accgagaccc ccgccgaggc agcgcagaca tcacagtggt caaacggcgc
    14821 ggcgaacggg aacggcgccg ccatcggtaa cggtgccgcc aaccgtgcag ccgccgccaa
    14881 cggtgcagcc gccggcaacg agaacggtgc cacggactgg agcggaaacg gcgccgccaa
    14941 cggtgcagcc gccgccaacg gtgcagccgc cggcaacgag aacggtgcca cggactggag
    15001 cggaagcggc gccgccaacg gtgcagccgc cgccaaccgt gcagccgccg gcaacgagaa
    15061 cggtgccacg gactggagcg gaaacggcgc cgccaacgcg gacaacgccg ccgatgcggc
    15121 caacgttctt caggacgaga atctcagcga cggcgccggt gtcctggtgc aggcgggcgg
    15181 ttccgccgag ttcgaaaagt cccacgtgga gcacaacctc gcgggtggac tcgggggtgg
    15241 gatcgccaac ttcggcaaga ccagcctcta ccacaccacc gtggccgaca accacgcctt
    15301 ccaattcggt ggcggcatct tcaacgccgg aatgctgaaa atctcctcgt cgagggtgaa
    15361 ggacaacggc gccatcatcg gcggtggcgg catctccaac ggagcggcac tcgtcgacgg
    15421 tgaggacacc gacgccggca cggtccggat cgagaaggcc gagatcaccg ccaatgagac
    15481 gctcggcttc ggtggtggcc tgctcgacat cgggggcgac accacgatca cgcagtcgaa
    15541 gatcaccagc aacctggcgc tcctcgccgg tggtggcatc gcggcggtcg ggcagagcaa
    15601 cctctacctg aaggagacag aggtcgccaa gaacaccacc accggtgccg gcggcggctt
    15661 ggccctggtg ctcggtgcca tcgtcaacgt ggacaagagc aaggtcctgg acaacaaggc
    15721 cgttaccttc ggcggcggtg tgttcaacgt cctcagcgcg gtcaccttcc ggaacagctc
    15781 ggtctccggc aacctggccg ctgtctccgg cggcgggatc ttcaacgtcg cgggagcggt
    15841 tgacctgacc gcctccaagg tgacgaagaa ccgctccacc ttcgagccgg gtggcgtgtt
    15901 cagcgcactg ggcgaggtta cggtggacaa caagtccgcg atcaagggca acgacccgac
    15961 caactgccag ggcagtgtcg acgagatcga gaactgcttc ggctgatcga ccagctcgcc
    16021 agtccggccc cctccgctga cgcggagggg gccggaccct gttgtgcggg tactaccgct
    16081 gcacgaagac cgtcaggctg cgagccggaa ccgtgaaggt gccgctgtcg gccgcgaacg
    16141 aggacgtccg cagcagctcg tcggcggagg tgcgcagcac cgggtgcagt gtcacgtccg
    16201 ccccgcgtag gtcaatgagc tgttgggtgg ccggctgcgg ggtggcgttg aagatcaccg
    16261 tcactgactt ccacggacca cccagcccac ggctgtccag cgtcatcgtc agcacaccgg
    16321 gctgctccgt acggccggac aacggaaagg ccacccgccg ctgcacctgc tctgctgtcc
    16381 gcaacccgaa caccggcgac gaggagcgaa tccggagcag ttcggcaaaa cgagcttcgg
    16441 ccaggtccat cgtcgcgcag ccgggcacca gccccgggtc ggccagcagg ggccgggcgt
    16501 acggccactt gtccttgttg tccgactcgg gcggaagccc gacgccgaac ccgttgccct
    16561 gtgcgcattc ccagcggatc tggttgaacc agtcacccga gttgtacgag ttgcggtcca
    16621 gcgacttcga ccgcagccgc tcggtgccgg cggtgacgaa gccggtgccc tgccccagca
    16681 cggcggtgcc gagcgcgagc acctgcatcc gggcccggtc caccgccgtg gtgtccgccg
    16741 gcagcttgta cgccagcgcg tcgtacagga tctcgttgtc gtgcgcgtcc acgtaggtga
    16801 ccgactcacc cggcgcggcc gtgtagccgg ccggggatcc gttgtagtcc acctgcgccc
    16861 cggtgacctg ctcacccgcg gtgttggtga accggtagcc gcgcagattg ccgctgagcc
    16921 ccaccttgat caggtcatgc tggtgcagca gtcgggcgcg ctgctgcgcc gtcgaaccgt
    16981 tgaccgggtc gttgttgggg tcggtgaaca gcccggaggc gaagccctgc tgccgcggat
    17041 tggcgtcgaa gggaccgccc ccacgcaccg cgtcccggag ccgatcgttg aaggtgccga
    17101 tacccgtgcc ggccatgttg gcctgggttg cctgaacgaa ccgcgcgccg tcggccacct
    17161 cgccgaagtt ccagccctcg ccgtacagca ggatgccccg accgtccacc ccgtcgcggg
    17221 cgacggtcag ctcgtccaga gccgcgcgga cggccagcat gttcgccttc gggtggtgac
    17281 ccatcaggtc gaaccggaag ccatccacct tgtattcttt cgcccaggtg accaccgagt
    17341 cgaccacgag cttgcccatc atggcgtgct cgggagcggt gttggcgcag caggtcgagg
    17401 tggcgaccga gccatccgcc agcagccggt ggtagtagcc gggaaccacc tggtccagga
    17461 ccgacttcgg gtcggtgccc gtcgccgagg tgtggttgta gacgacgtcg agcaccaccc
    17521 gcagcccggc gccgttcacc ccggcgacca tccgtcggaa ctcggtggtc cgcgccgccc
    17581 cggccgggtt gaccgcgtag ccgccctccg gcacggtgta gtgcagcggg tcgtaccccc
    17641 agttgtagcc gtcggtgtcc gccaccgcgg cgacgcagcg ttgttgttcg tccgagtccg
    17701 gcgggagcgc tgccaggtcg caggggggtt gctgctggtc ggcgcggcgt tcggggatcg
    17761 tggcgaagtc aaacgccggg agcaggtgca ggtgggtcgt cccggcgtcg ccgagcgcct
    17821 tcaggtgtcg cattcccgcg gtgaccgggt cggtaaaggc acggaacgtg ccgcgtcgct
    17881 cggccgggac cgtactgtca gcgatcgaga agtcccgcac cgacagctcc gagatctgcg
    17941 ccttcgtcgc cggtaccgcc gccggcttac gcaggttcgt ccagcccggt ggtgcgagcc
    18001 gcgggtcggc gagatcgacg atctggctgt gggtggagtc gggtgcgagc gccagcgagt
    18061 acgggtcggt caccgccgca gttaccatct gctgctccgc cggctgccac gcctcgaccc
    18121 ggtagcggta gtacttcccg gtccaggagg gggttccccg caccgaccac acaccggtgc
    18181 ggtcatcccg actcatggtg accggccgcg gtcgcgccgt cggagtgtcg aacaactcca
    18241 gcgtcaccgt acgggcggtg ggagcccaga ccgcgagcgt cggcaccgca ccggcgaagg
    18301 ttggaccgag tcgcgcccga gtcgccgggg cgtagatgtc atcgagcaca cccgggacct
    18361 gcacaccggt ggcgacgcgc agggtgccgt cggtgtcccg ctcggtcacc acaagctgcc
    18421 cgcgcagcgc cgccggcacc ccggccaggt gcttccggtc caggacgaga gcctgatacg
    18481 ccgccaggtg cggaaaccgc tcgcgttgtg ccttggtcag cccgtggtgc cggacacgta
    18541 gcggaactgt ccggtacgtc ccggcgagtt caccgtcgac aatggtcacg ccaccggaag
    18601 cggcggcgac cagcgcgtac gtcgtgccgc ccggtggtcc ggtcggccag gcgagggtgc
    18661 cgcgatcgat ccagtgtgcc ttctgcctgg tcaggtcgag gtccgtggtg gtgccgggct
    18721 ccgattggtc ttcgccggcg gtgagcagcg tggcggagtg gtcgacagcc cactgctcgg
    18781 taccggccat ggcgagcacg tcggtgccgg cggatgggtc gatgtggacg aacgtgttgg
    18841 tgccggcgag ggtgagggtc gccagcgagg cgagagtgag cagcgccttg cgcgggatcg
    18901 gcgggggttt catcgacggc cttcctctgg tcgctgatga gccgcacgct agcttccacc
    18961 gaaagttact gcaaggcttt gcaaccgcaa ccgcacgaca cccggccgag ggccgacaca
    19021 ccaggcgaac cgccggcccc gctccacccc accaaccaaa ggttgcatga atagcaagac
    19081 ggacgtacgg tttgtagagc agtcccgtac gggtaagggc cacctaagca acgcaccgcc
    19141 ctcgccggtg cgacagactg ctcaggactg ctcacggcca ctggtgtgaa ggagtacgac
    19201 gtggcgagcc tcgacacctt cggtgcgaag acccagctac gcgtcggcga cgcgagctac
    19261 gagattttca agatcaacaa ggtggagggg cacgatcggc tcccctacag cctgaaagtc
    19321 ctcctggaga acctgctccg gaccgaggac ggcgcgaaca tcaccgccga ccacatccgg
    19381 cagctcggcg cctgggagcc gaccgccgac ccgagcgtgg agatccagtt caccccgtca
    19441 cgggtgctga tgcaggactt caccggcgta ccctgcgtgg ttgatctggc caccatgcgt
    19501 gaggccgtgc gtgacctggg tggcgacccg accaaggtca acccgctcgc cccggccgag
    19561 ctggtcatcg accactccgt catcgccgac ctgttcggcc gggaggacgc cttccagcgc
    19621 aacgtcgagc tggagtatga gcgcaacaag gagcgctacc agttcctgcg ctggggtcag
    19681 accgcgttca acgagttcaa ggtcgtcccg ccgggcaccg gcatcgtgca ccaggtcaac
    19741 atcgaatacc tcgcccgtac ggtgatggag cgtaacggcc aggcctaccc ggacacagtg
    19801 gtcggcaccg actcgcacac cacgatggtc aacggcctcg gcgtgctcgg ctggggcgtc
    19861 ggcggcatcg aggccgaggc cgcgatgctc ggccagccgg tcagcatgct catcccgcgg
    19921 gtcgtcggct tcaagctctc cggtgagatg ccggccggca ccaccgccac cgacctggtc
    19981 ctgaccatca ccgagatgct gcgcaagcac ggtgtggtcg gcaagttcgt cgagttctac
    20041 ggccccggtg tcagcgcggt tccactggcc aaccgggcca ccatcggcaa catgtccccg
    20101 gagtacggct ccaccgtcgc gatcttcccg atcgacgccg agaccgtccg ctacctggag
    20161 ctgaccgggc gtgacccgca gcaggtcgcg ctcgtcgagg cgtacgcgaa ggagcagggc
    20221 ctctggcacg atccggccgc ggagccgaac tactcggagc ggctggaact ggacctgggc
    20281 agcatcgagc catcgctcgc cggcccgaag cggccccagg accgggtgcc gctgggcaac
    20341 gccaagacct tgttccgggc cgcgctcacc gactacgtcg ccacggacgc gaccggaggc
    20401 gagcagaagc agggcatcaa cggccccgcc gacgaggcca gcgccgagtc cttcccggcc
    20461 agcgatgccc ccgccaacaa ggtcatcgac cccgctgacg ccccgcgcga cctggtgacc
    20521 gcggcggtgg gctccggcgg ccgggccacc agcccgatcc gggtcaccgg tgccgacggc
    20581 accgagttcg agctggacca cggtgcggtg gtgatcgccg ccatcacctc ctgcaccaac
    20641 acctccaacc cgcaggtgat gatcggcgcc gcgctgctgg cccgtaacgc ggtggaccgg
    20701 ggcctggccc gcaagccgtg ggtgaagacc accctcgccc ccggctcgaa ggtcgtcatg
    20761 gactactacg agcgggccgg tctcacccca tacctggaga agctcggctt ccacctggtc
    20821 ggctacggct gcaccacctg catcggcaac tccggcccgc tgccggagga gatctccgcg
    20881 gcggtgaacg agaaggacct ctcggtcgtc tcggtcctct ccggcaaccg caacttcgag
    20941 ggccggatca acccggacgt caagatgaac tacttggcgt ccccgccgct ggtggtcgcg
    21001 tacgcgctgg ccggaacgat ggacatcgac ctggccaatg agccgatcgg cgaggacgcc
    21061 caggggagcc cggtgttcct gcgcgacatc tggccgagca gcgccgagat ccaggacgtc
    21121 atcgcctccg caatcggcgc cggcggcttc agctcggcat acgcgaacgt cttcgccggc
    21181 gacgagcggt ggcagtcgct gccgacgccg accggtaaca ccttcgcctg ggagggcgag
    21241 tcgacctacg tccgcaaacc cccgtacttc gagggcatgc gacgcgagcc ggcgccggtc
    21301 cgcgacatcg gagcggctcg ggtcctggcc aagctcggcg actcggtgac caccgaccac
    21361 atctcgccgg ctggcgcgat caagcccgac tcccccgccg gccggtacct cgccgcgcac
    21421 ggcgtgccac gacacgagtt caactcgtac ggctcccgcc ggggcaacca cgaggtgatg
    21481 attcggggca ccttcgccaa cattcggctg cgtaaccagc ttcgggttcc cggtgccgac
    21541 tccgctgccg gggccacgct tcccgagggc ggcttcacgg tcaaccacct gaccggcgag
    21601 cagagcacca tctacgacgc cgcggtggcc taccaggagg cggagatacc gctgatcgtc
    21661 ctggccggca aggagtacgg ttcgggctcg tcccgggact gggccgccaa gggcacgatg
    21721 ctgctgggcg tcaaggcggt catcgccgag tcgtacgagc ggatccaccg ctccaacctg
    21781 atcggcatgg gcgtcctgcc gctgcagttc ccggccggcg agaccgccga gtcgctgggc
    21841 ctgtccggtg tcgagtcctt cgccatcacc ggggtcaccg ccctcaacga gggcgacacc
    21901 ccacggaccg tacgggtcac caccgacacc ggggtcgagt tcgacgcggt ggtccgcatc
    21961 gacaccccgg gagaggcgga ctacttccgg cacggcggca tcctgcagta cgtgctgcgc
    22021 cggatgatcg gctaagcagt aacggacggg gcccccacac cggtgggggc cccgtcgcgt
    22081 atccgtcggc gggtaggccg gggttaggca cccgagccgg ctgaccgggc gttgcctcgg
    22141 ggcagccgcc cgatcccgga cgtgatctcg ccacgctgtg tcaggctcgt ggtcatggac
    22201 gacaagacca tcctgaagcg catctccgag ctggttgacg aggaacacca gctccgcgcc
    22261 gaagcccagg ccaacgagga gggcaccgac gaggagagcc gcgaccggct acgggatctg
    22321 gcggagtcgc tggaccagtg ctgggacctg ctccgccgtc ggcgcgccgc ccgctccacc
    22381 cacggcgacc cggaggccca gggcgttcgc ccggcaccgg aggtggcgcg ctacctccag
    22441 tagggcgggc accaggccct cccaagcagc tgccgttgcg gcaccgggct accgcgccga
    22501 ccgcccggga gcaccttggc gccagggcaa gcccgcctct cggagcagcg ttcaacgcag
    22561 gcccgcctcc cggagcagct gttcggtaag ggcgagcggt tctgcctgct ccgccggcag
    22621 gccacgggcg gcgaaccagg tggcaaccac ccgaacgtct cgggccaggt actccggccc
    22681 ctgcggattg gcgaccacat ccacgacctg aggcaggtcg atgagcacca ggtgcccctc
    22741 gtgcaccagc aggttgtagg gcgacagatc accgtgtgcg tagccaactc gggcgagtac
    22801 caccagcgcc tcgacgagtt gttcccacag gtcacgcagg tcggcctccg tcggccgcag
    22861 ctgcgccagc cggggggcgg cctgcctctc gtcggagtca ccgagaaact ccagcatcag
    22921 ctcggtgccg cggagctgaa ccgggtaggg cacggtgatc gtgccgtacc gcgcaccgat
    22981 ctcccagagg cggccgagca cggcaaactc cgctgccgcc cactgtccgg cgatcatctg
    23041 ccggccgaac gcggttcgcc gggtcatcgc ccgcatctcc cgggagcgtc ggacgcgccg
    23101 cccctccaga tatcccgcgt cccggtggaa tagccggtgg tcggcatctc ggtatcgttt
    23161 ggccgcgagc aggcaggacc gatcggtgtc gggcacggca cgccggacga gatggacgtc
    23221 cgcctccttg ccggtcttga ggacgccaag ttcggtgtcc gtggcggcca gctccgttac
    23281 cagccaggaa gggtacggct ccggaccgtg gactgcgtcg tcccaggacg accaggtctg
    23341 ggcttctggc ggagggtcgg agtcagcggg ctgcggcccg gtgcgccgcc cgcgcttgga
    23401 gaagtgtggt tcgtcatcat cgaagcggcg tctgccgcgg gtccggcgct ccggcgccgg
    23461 agagtcgtga tcgcgcactg cggtgagatc ccttgatcga ggtcaatcga ggcagatgga
    23521 agtgacctgt gaagacggcc atgaccgacc tcctctcctc gaccggaccc acgcgcccgg
    23581 ggtgcaccgt gcggtcccat gctcactgtc ggatcgccgc gaggcaaccg gtattacgcc
    23641 gcgagtaccg cggcgagggc ggcgatcaga ccgtcgaccg tgaaggtggg ggcgaaccgt
    23701 ccgtcggtcc aggtgcgccc ccggtgcagc cagacgctgg gcagccccgc agccgcggca
    23761 ccgccgatgt ccgcctccgg tccgtcgccg accacccagg ccccgcgcag cggcatacga
    23821 acccgctgcg cggccagtgc gaagatccgc gggttcggct tgctgacacc ggccgcctcg
    23881 gagatcaccc agtcggcaag gtaacggtcc agcccggtcc gtcggatctt ctcctcctgc
    23941 ggccgtaccg ccccgttaca caccaccacc ggcatccacc cggcgtcgcc ggcgatctgc
    24001 agcgcgcacg ccaccagtgg atccagacgg gtgccggcga gcaccccctc gtgcagctcc
    24061 tccaccaggt cgaccgagcg gacggccaac gagtagcggt cacggatcgc atcggccaca
    24121 tcccaccgat cggtcagccc gtccgcgtcg acggagagca gccagtcgag gtcatccggc
    24181 ggtgcgccga tcttgaccag gaagcgctcg ccccaggatc ggaacagatt ttctcgatcg
    24241 agcagggtgt tatccaggtc aagaaggagc agcggcactc cggcacctta cgggactgag
    24301 gcgtccgccc gacaggtccg gacagctaaa tggtcagaat tttgtgacaa acggatgaag
    24361 tacccagtag gagaactcgc cgaagggagg acgcgggctg ccagccgacg ggtcagaccg
    24421 caagccgtac gtacggtttg caggacgccg ggtgttttga cacgatcgac ccgtgcccag
    24481 agtaagccag gaccaactcg acgcgcgccg gcaggagatc ctcaccgccg cccgggtctg
    24541 cttcgcccga cacgggtacg agggcgccac cgtgcggcgc ctggaggagg ccaccgggct
    24601 gtcccgtgga gcgatcttcc accatttccg cgacaaggat tccctcttcc tcgcggtggc
    24661 cgaggacgat gcggcggcga tggtcgaaac cgtcgcccgc aacggcctgg tgcaggtcat
    24721 gcgagacctg ctggctcggg ctgcctcccc cgacacgaca ggctggttgg gcagccagtt
    24781 ggaggtctcg cgccggctcc gcaccgatcc cgcgttcgcc cggcggtgga ccgaacggtc
    24841 cgcggcgatc gccgaggcca ctcgcgaccg cctgctccgc cagcgcgagg cgggcgtcct
    24901 gcgcgacgat gtccccatcg atgtgctcgc ccagttcctg aagctggcgt acgacggtct
    24961 ggtcctgcat ctggcgatgg gccgacccgc cgacgacctc ggaccggtac tcaacctggt
    25021 cgaggaggcc gtccgtcggc ggtga
//
