BGC0001113: spliceostatin biosynthetic gene cluster from Burkholderia sp. FERM BP-3421
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 93,443 nt. (total: 93,443 nt).
This entry is originally from NCBI GenBank KJ461964.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001113
Short description spliceostatin biosynthetic gene cluster from Burkholderia sp. FERM BP-3421
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: KJ461964.1
Compounds
  • spliceostatin
  • FR901464
Species Burkholderia sp. FERM BP-3421 [taxonomy]
References
Chemical products information
spliceostatin
Copy SMILES
C51H82N6O12S1
Chemical database entries
PubCHEM
FR901464
Copy SMILES
C27H41N1O8
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AIC32690.1
  • fr9A
 3153 - 4037 (+) FR9A
copy AA seq
copy Nt seq
  • AIC32691.1
  • fr9B
 4352 - 5434 (+) FR9B
copy AA seq
copy Nt seq
  • AIC32692.1
  • fr9C
 5908 - 21093 (+) FR9C
copy AA seq
copy Nt seq
  • AIC32693.1
  • fr9DEF
 21115 - 44859 (+) FR9DEF
copy AA seq
copy Nt seq
  • AIC32694.1
  • fr9GH
 44915 - 59674 (+) FR9GH
copy AA seq
copy Nt seq
  • AIC32695.1
  • fr9I
 59676 - 68834 (+) FR9I
copy AA seq
copy Nt seq
  • AIC32696.1
  • fr9J
 68894 - 69784 (+) FR9J
copy AA seq
copy Nt seq
  • AIC32697.1
  • fr9K
 69795 - 71084 (+) FR9K
copy AA seq
copy Nt seq
  • AIC32698.1
  • fr9L
 71102 - 71857 (+) FR9L
copy AA seq
copy Nt seq
  • AIC32699.1
  • fr9M
 71933 - 72172 (+) FR9M
copy AA seq
copy Nt seq
  • AIC32700.1
  • fr9N
 72165 - 73430 (+) FR9N
copy AA seq
copy Nt seq
  • AIC32701.1
  • fr9O
 73442 - 74575 (+) FR9O
copy AA seq
copy Nt seq
  • AIC32702.1
  • fr9P
 74909 - 75934 (+) FR9P
copy AA seq
copy Nt seq
  • AIC32703.1
  • fr9Q
 76179 - 76616 (+) FR9Q
copy AA seq
copy Nt seq
  • AIC32704.1
  • fr9R
 76711 - 78159 (+) FR9R
copy AA seq
copy Nt seq
NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
fr9DEF
Module ?
Specificity: threonine
Evidence for specificity:
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.