LOCUS       BGC0001187             12562 bp    DNA     linear   PLN 02-JUL-2015
DEFINITION  Glarea lozoyensis strain ATCC 20868 glpks3/glnrps7 operon, complete
            sequence.
ACCESSION   BGC0001187
VERSION     BGC0001187
KEYWORDS    .
SOURCE      Glarea lozoyensis
  ORGANISM  Glarea lozoyensis
            Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
            Leotiomycetes; Helotiales; Helotiaceae; Glarea.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 23:45:15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12562
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..12562
                     /country="Spain"
                     /culture_collection="ATCC:20868"
                     /db_xref="taxon:101852"
                     /isolation_source="pond water from Valle del Rio Lozoya"
                     /mol_type="mRNA"
                     /organism="Glarea lozoyensis"
                     /strain="ATCC 20868"
                     /type_material="culture from holotype of Glarea lozoyensis"
     subregion       1..12562
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="NRP, Polyketide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12562
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            499..9519
                     /gene="glpks3"
                     /operon="glpks3/glnrps7"
     CDS             499..9519
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (54-475). E-value:
                     4.2e-177. Score: 581.1. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (584-893). E-value: 6.6e-92.
                     Score: 299.9. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (969-1150). E-value: 4.5e-20.
                     Score: 64.5. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_ER (1646-1964). E-value: 4.6e-112.
                     Score: 366.0. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_ER.1"
                     /NRPS_PKS="Domain: PKS_KR (1989-2163). E-value: 5.6e-53.
                     Score: 171.4. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (2264-2341). E-value: 2.8e-14.
                     Score: 45.1. Matches aSDomain:
                     nrpspksdomains_glpks3_PKS_PP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (2392-2693). E-value:
                     4.2e-61. Score: 198.4. Matches aSDomain:
                     nrpspksdomains_glpks3_Condensation_LCL.1"
                     /codon_start=1
                     /gene="glpks3"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     itr_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 255.2; E-value:
                     2e-77)"
                     /gene_kind="biosynthetic"
                     /note="polyketide synthase-nonribosomal peptide synthetase"
                     /operon="glpks3/glnrps7"
                     /product="GLPKS3"
                     /protein_id="AKL78824.1"
                     /sec_met_domain="Condensation (E-value: 5.1e-51, bitscore:
                     160.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-17, bitscore:
                     50.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.5e-10, bitscore:
                     26.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 2.4e-93, bitscore: 299.9,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="itr_KS (E-value: 8.2e-181, bitscore:
                     588.4, seeds: 96, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 3.1e-52, bitscore:
                     164.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.2e-22, bitscore:
                     66.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSALAPQLVSRMQSYDSRVSIDGLSDANLQSGNTSTDATSVSSQE
                     EVAHVPENTAIVGMACRLPGAKSPQQLWKNIVDQRDVQRKIPKERFNVDAFYHPEGTNK
                     GTTNARYGYFLDDDVSEFDPEFFQISGKEAEAMDPQQRLLLEVVYEALENAGITLDEIS
                     GTETSVFCGSFTNDYREMIHKDLEHYPKYSVTGTGAAILANRISYFYNLHGPSVTLDTA
                     CSSSLVGLHMGNQSIRDGEADISIVVGSALHFDPTIYTTMTDLGFLSVDGRCRAFDAGG
                     SGYVRGEGICAVILKRKSQAQMDGNNIRAIIRGTGCNHDGIKEGITMPNSVAQEALIRR
                     VYKNTGLNTNETQYFEAHGTGTQAGDPRETRAIGAVFAPNRDRPLYVGSVKTNIGHLEG
                     ASGLAGVIKTTMSLEAGKILPNMLFNNPNPKIDFEQWKITVPTKIIDWEPTNGVRRASV
                     NSFGYGGTNAHIILEGYNKPAVVEEVVKLIPEYEEMVSERPFLLPLTSHTEKAGNLLKN
                     NLSTFIAGENVSAPDAALSLSNPGRSNHQYRSYVIGQDSDEMIEKLSTTTGGTPWTRAT
                     KTKPRIGYVFTGQGAQHYHMGRELLEKCPMFKQSIQKCDEILQSLEAPPSWSVLTELMK
                     SKEDSLVNGIEFSSSLATAIQLSTIDLLRAWGVEPAAVCGHSAGEIPASYAAGILSFKD
                     ALACAYYRGCALSGEPEDKVQIPGAMVAVGMTESEAIVELEKYGGAVKIAAVNSPTSLT
                     LSGDEPQVVELQKSLEDRKVFARRLAVERAYHSHHIAPYAPELTRLSRNVRPRPATCRM
                     FSSVTARIAEWQKMTGAYYALNLVNQVRFSDALTGILIDENEEQNVDVLIEIGAHPALK
                     GPSRQTIQALKLDVPYLATIARGANDFEGMLATVGQLYAMGYPVDLEAVNSDLFLGSDG
                     AVVRAPAGKTVDLPSYSWDHSKYWAETRLVKSYRNRAHRHSILGAPMLGNLEKHPRWRS
                     FLRPRELQWLPHHMIDGKVIFPAAGYLTMAIEAAVRLETCPKNIKAICLRDIAIKSALT
                     VSDSEMGTEVIFEMQPVSTSAKRTSDTWYRFIINSFGDNGVVNEHCYGLISVEAGDSTA
                     IETDTPAPSLAQLRKRSDRCTTSKTFYEHLWNIGLQYGEDFQLITGNVDSGSGYSMAPI
                     SLKPAALMTTPNDHCVIHPSFLDASFHPFFAGIESLLGRPLDGPFVPTFMKYLKLSGAF
                     FDLTQGTAEHTLWATAETKLPGPRVAISDITVRSADCSEILIDMQGLEATALGSSTAET
                     SRQLFFRTRWQPAFDNLAGTAELSALKTPAEIMDVYAHQYPDTKILHITSDLAATKELL
                     TTLFPQQRRRFQSITPYCGSEEQFEDIEALTKVYSTLIDTAEPKEGAYDLVVVSKTTSL
                     DVKSFLNSTGHVIVAGGEYDGQGMSVLFQNSSFTAYTEAYSSNYTAKPLTLVMGKKVSE
                     TTEALAQLITSKQTAPVTRMSFVDMVENAPATENVIVLASLDQELFFEDPEHEEIHFEA
                     VRTFFTSENKNIVWIVRGASQETSNPAQAMILGMCRVARNENDKLKVVTLDVAETAQNG
                     QIAEQINTILDSRLTEDEYAARNGTLSIPKIETDDLLNNKLPENSGGDAVMQEFGAGQP
                     LALKIGKVGLLETLAFGVDEDIVDTELAADSIEVEVKASAINFRDVAASIGIIDDYRLG
                     DECAGVVLRIGSAVNPNDFQVGDRVVAFRPGQGAHRSIVREQAALCYKLPENISFTTAA
                     AFTCIMITAYYAFHDLARLQPGEKVLIHAAAGGVGQMAIQVAQMMGAEVIATCGSQAKR
                     DLLKSTYGLTDDHIFSSRDPSFVADINRLTNGKGVDVVLNSLAGDLLHATWACVARFGR
                     FIEIGKRDIHENAKIDMEPFRKSVGFASLDLITMYEYNKPLSHRLLNETYKLLEQGKIN
                     NPHSVLELPYSEAEKGFRLLQMGKHTGKIVLVPHKDDIVPVSLPSYRKTMLFSPEKSYL
                     LSGGLGGLGRTMAEWMVRKGARQLAFLSRSGDARPEAKATVEWLQARDIKVTIFKVDVS
                     DYAAVTKAVQSLGDNLAGIFHAAVVLQDAPLNTMSLKQWQGCVHPKVQGAWNLHRATLH
                     LDLDFFTPFSSVACQVGAMGQTNYAAANTYLDALVRYRRSIGLKASSMNCGMIVGVGLV
                     AENESILNWLIKMGSDGVNEDELLYQIEEAVVGGSAPTQLTARGIDPAATTTGVQTARN
                     DVYWHGRAFFRNLYSNFDVAGAGAAKGGNSLGALLQAAKDVPERAQILTEAFIEKIAAV
                     LGVVAETIQPGNPLSMYGLDSIVAVEFRKWFSKTINVDIALFDILSSKSIALLVLKAAS
                     LMVIEVAASEKSKGSSEETKGSAAVSEQATAGEQSSDFDAISIARPSNIPMSTFQRRMW
                     YAHNLVEDKSALNICITSHIKGTPDATIFKAALDELKRRNEMLRTAYSEGDDFAEQEPV
                     ADFDSRLVYRDLSTEIDVDASLESWRASLQGEELDIENGEIMRPGLFKLGDEKFAFVVA
                     FHHISIDRGSSKALFEQFVEIYDAIRLEKDLASVAPPRISYTDFSIWYENHLRSAGLQS
                     EVEFWKQRLAGIKPTSELLPFAKTTRPDTMDRVRDELRSTLPLSMLLRLKRVCARMGTT
                     PFQFMLAAFRAFLFRYTEEEDVTVLVIDGNRPRSDLEDVLGFFVNMIPVRLNNVDSDSL
                     FDSVLSSTKSATVEAIEHSKIPFDTIVEAVNLPKSHSIFPISQVVVNYQMHGKMPRFGT
                     EDFHIHTVINHDIPTACELALEALEDPDKGLDLRLEYSTTLYAEADMERFFDNFSTFLT
                     SLIRDHRQPIAQTQMTGPKEVEHLKTNYWNMGFTENTWKGASVVEKILKKAEETPDALA
                     IQTAENGNLTYKQLVDQAQRIAATLEQANIAPGTSVGVLASPGADAVVAMVGALIRGCG
                     YLAMDPEFAAQRLSFMASDSAVKLILVGEDLESVGCAVAAKTTSPPQVMPIAVAKSSNE
                     KSRVAQVSRKA"
     operon          499..12209
                     /operon="glpks3/glnrps7"
     aSDomain        661..1923
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_KS.1"
                     /domain_subtype="Iterative-KS"
                     /evalue="4.20E-177"
                     /label="glpks3_PKS_KS.1"
                     /locus_tag="glpks3"
                     /protein_end="475"
                     /protein_start="54"
                     /score="581.1"
                     /tool="antismash"
                     /translation="AIVGMACRLPGAKSPQQLWKNIVDQRDVQRKIPKERFNVDAFYHP
                     EGTNKGTTNARYGYFLDDDVSEFDPEFFQISGKEAEAMDPQQRLLLEVVYEALENAGIT
                     LDEISGTETSVFCGSFTNDYREMIHKDLEHYPKYSVTGTGAAILANRISYFYNLHGPSV
                     TLDTACSSSLVGLHMGNQSIRDGEADISIVVGSALHFDPTIYTTMTDLGFLSVDGRCRA
                     FDAGGSGYVRGEGICAVILKRKSQAQMDGNNIRAIIRGTGCNHDGIKEGITMPNSVAQE
                     ALIRRVYKNTGLNTNETQYFEAHGTGTQAGDPRETRAIGAVFAPNRDRPLYVGSVKTNI
                     GHLEGASGLAGVIKTTMSLEAGKILPNMLFNNPNPKIDFEQWKITVPTKIIDWEPTNGV
                     RRASVNSFGYGGTNAHIILEGY"
     aSModule        661..7521
                     /complete
                     /domains="nrpspksdomains_glpks3_PKS_KS.1"
                     /domains="nrpspksdomains_glpks3_PKS_AT.1"
                     /domains="nrpspksdomains_glpks3_PKS_DH.1"
                     /domains="nrpspksdomains_glpks3_PKS_ER.1"
                     /domains="nrpspksdomains_glpks3_PKS_KR.1"
                     /domains="nrpspksdomains_glpks3_PKS_PP.1"
                     /iterative
                     /locus_tags="glpks3"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       1138..1182
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0001"
                     /evalue="8.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="glpks3"
                     /protein_end="228"
                     /protein_start="213"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPSVTLDTACSSSLV"
     CDS_motif       1327..1365
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0002"
                     /evalue="8.80E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="glpks3"
                     /protein_end="289"
                     /protein_start="276"
                     /score="9.5"
                     /tool="antismash"
                     /translation="FDAGGSGYVRGEG"
     CDS_motif       1558..1605
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0003"
                     /evalue="1.20E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="glpks3"
                     /protein_end="369"
                     /protein_start="353"
                     /score="11.4"
                     /tool="antismash"
                     /translation="YFEAHGTGTQAGDPRE"
     CDS_motif       1660..1704
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0004"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="glpks3"
                     /protein_end="402"
                     /protein_start="387"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GSVKTNIGHLEGASG"
     CDS_motif       2248..2301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0005"
                     /evalue="3.60E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="glpks3"
                     /protein_end="601"
                     /protein_start="583"
                     /score="13.3"
                     /tool="antismash"
                     /translation="YVFTGQGAQHYHMGRELL"
     aSDomain        2251..3177
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_AT.1"
                     /evalue="6.60E-92"
                     /label="glpks3_PKS_AT.1"
                     /locus_tag="glpks3"
                     /protein_end="893"
                     /protein_start="584"
                     /score="299.9"
                     /tool="antismash"
                     /translation="VFTGQGAQHYHMGRELLEKCPMFKQSIQKCDEILQSLEAPPSWSV
                     LTELMKSKEDSLVNGIEFSSSLATAIQLSTIDLLRAWGVEPAAVCGHSAGEIPASYAAG
                     ILSFKDALACAYYRGCALSGEPEDKVQIPGAMVAVGMTESEAIVELEKYGGAVKIAAVN
                     SPTSLTLSGDEPQVVELQKSLEDRKVFARRLAVERAYHSHHIAPYAPELTRLSRNVRPR
                     PATCRMFSSVTARIAEWQKMTGAYYALNLVNQVRFSDALTGILIDENEEQNVDVLIEIG
                     AHPALKGPSRQTIQALKLDVPYLATIAR"
     CDS_motif       2497..2589
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0006"
                     /evalue="1.70E-10"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="glpks3"
                     /protein_end="697"
                     /protein_start="666"
                     /score="33.3"
                     /tool="antismash"
                     /translation="GVEPAAVCGHSAGEIPASYAAGILSFKDALA"
     aSDomain        3406..3948
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_DH.1"
                     /evalue="4.50E-20"
                     /label="glpks3_PKS_DH.1"
                     /locus_tag="glpks3"
                     /protein_end="1150"
                     /protein_start="969"
                     /score="64.5"
                     /tool="antismash"
                     /translation="HSILGAPMLGNLEKHPRWRSFLRPRELQWLPHHMIDGKVIFPAAG
                     YLTMAIEAAVRLETCPKNIKAICLRDIAIKSALTVSDSEMGTEVIFEMQPVSTSAKRTS
                     DTWYRFIINSFGDNGVVNEHCYGLISVEAGDSTAIETDTPAPSLAQLRKRSDRCTTSKT
                     FYEHLWNIGLQYGEDFQL"
     CDS_motif       3490..3567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0007"
                     /evalue="1.20E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="glpks3"
                     /protein_end="1023"
                     /protein_start="997"
                     /score="33.8"
                     /tool="antismash"
                     /translation="WLPHHMIDGKVIFPAAGYLTMAIEAA"
     aSDomain        5437..6390
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_ER.1"
                     /evalue="4.60E-112"
                     /label="glpks3_PKS_ER.1"
                     /locus_tag="glpks3"
                     /protein_end="1964"
                     /protein_start="1646"
                     /score="366.0"
                     /tool="antismash"
                     /translation="GLLETLAFGVDEDIVDTELAADSIEVEVKASAINFRDVAASIGII
                     DDYRLGDECAGVVLRIGSAVNPNDFQVGDRVVAFRPGQGAHRSIVREQAALCYKLPENI
                     SFTTAAAFTCIMITAYYAFHDLARLQPGEKVLIHAAAGGVGQMAIQVAQMMGAEVIATC
                     GSQAKRDLLKSTYGLTDDHIFSSRDPSFVADINRLTNGKGVDVVLNSLAGDLLHATWAC
                     VARFGRFIEIGKRDIHENAKIDMEPFRKSVGFASLDLITMYEYNKPLSHRLLNETYKLL
                     EQGKINNPHSVLELPYSEAEKGFRLLQMGKHTGKIVL"
     CDS_motif       5830..5892
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0008"
                     /evalue="4.10E-10"
                     /label="PKSI-ER_m5"
                     /locus_tag="glpks3"
                     /protein_end="1798"
                     /protein_start="1777"
                     /score="31.8"
                     /tool="antismash"
                     /translation="GEKVLIHAAAGGVGQMAIQVA"
     CDS_motif       5902..5952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0009"
                     /evalue="7.00E-06"
                     /label="PKSI-ER_m6"
                     /locus_tag="glpks3"
                     /protein_end="1818"
                     /protein_start="1801"
                     /score="18.6"
                     /tool="antismash"
                     /translation="GAEVIATCGSQAKRDLL"
     CDS_motif       6031..6069
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0010"
                     /evalue="2.00E-05"
                     /label="PKSI-ER_m7"
                     /locus_tag="glpks3"
                     /protein_end="1857"
                     /protein_start="1844"
                     /score="16.9"
                     /tool="antismash"
                     /translation="TNGKGVDVVLNSL"
     CDS_motif       6115..6144
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0011"
                     /evalue="4.60E-03"
                     /label="PKSI-ER_m8"
                     /locus_tag="glpks3"
                     /protein_end="1882"
                     /protein_start="1872"
                     /score="10.4"
                     /tool="antismash"
                     /translation="GRFIEIGKRD"
     CDS_motif       6343..6390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0012"
                     /evalue="5.40E-05"
                     /label="PKSI-ER_m9"
                     /locus_tag="glpks3"
                     /protein_end="1964"
                     /protein_start="1948"
                     /score="16.2"
                     /tool="antismash"
                     /translation="GFRLLQMGKHTGKIVL"
     CDS_motif       6466..6564
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0013"
                     /evalue="5.90E-16"
                     /label="PKSI-KR_m1"
                     /locus_tag="glpks3"
                     /protein_end="2022"
                     /protein_start="1989"
                     /score="51.0"
                     /tool="antismash"
                     /translation="SYLLSGGLGGLGRTMAEWMVRKGARQLAFLSRS"
     aSDomain        6466..6987
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_KR.1"
                     /evalue="5.60E-53"
                     /label="glpks3_PKS_KR.1"
                     /locus_tag="glpks3"
                     /protein_end="2163"
                     /protein_start="1989"
                     /score="171.4"
                     /tool="antismash"
                     /translation="SYLLSGGLGGLGRTMAEWMVRKGARQLAFLSRSGDARPEAKATVE
                     WLQARDIKVTIFKVDVSDYAAVTKAVQSLGDNLAGIFHAAVVLQDAPLNTMSLKQWQGC
                     VHPKVQGAWNLHRATLHLDLDFFTPFSSVACQVGAMGQTNYAAANTYLDALVRYRRSIG
                     LKASSMNCGMI"
     CDS_motif       6784..6813
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0014"
                     /evalue="8.60E-04"
                     /label="PKSI-KR_m3"
                     /locus_tag="glpks3"
                     /protein_end="2105"
                     /protein_start="2095"
                     /score="12.6"
                     /tool="antismash"
                     /translation="PKVQGAWNLH"
     CDS_motif       6835..6945
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0015"
                     /evalue="2.00E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="glpks3"
                     /protein_end="2149"
                     /protein_start="2112"
                     /score="59.0"
                     /tool="antismash"
                     /translation="LDFFTPFSSVACQVGAMGQTNYAAANTYLDALVRYRR"
     aSDomain        7291..7521
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_PKS_PP.1"
                     /evalue="2.80E-14"
                     /label="glpks3_PKS_PP.1"
                     /locus_tag="glpks3"
                     /protein_end="2341"
                     /protein_start="2264"
                     /score="45.1"
                     /tool="antismash"
                     /translation="AAKDVPERAQILTEAFIEKIAAVLGVVAETIQPGNPLSMYGLDSI
                     VAVEFRKWFSKTINVDIALFDILSSKSIALLV"
     aSDomain        7675..8577
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glpks3_Condensation_LCL.1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="4.20E-61"
                     /label="glpks3_Condensation_LCL.1"
                     /locus_tag="glpks3"
                     /protein_end="2693"
                     /protein_start="2392"
                     /score="198.4"
                     /tool="antismash"
                     /translation="SNIPMSTFQRRMWYAHNLVEDKSALNICITSHIKGTPDATIFKAA
                     LDELKRRNEMLRTAYSEGDDFAEQEPVADFDSRLVYRDLSTEIDVDASLESWRASLQGE
                     ELDIENGEIMRPGLFKLGDEKFAFVVAFHHISIDRGSSKALFEQFVEIYDAIRLEKDLA
                     SVAPPRISYTDFSIWYENHLRSAGLQSEVEFWKQRLAGIKPTSELLPFAKTTRPDTMDR
                     VRDELRSTLPLSMLLRLKRVCARMGTTPFQFMLAAFRAFLFRYTEEEDVTVLVIDGNRP
                     RSDLEDVLGFFVNMIPVRLN"
     CDS_motif       7744..7854
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0016"
                     /evalue="4.70E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="glpks3"
                     /protein_end="2452"
                     /protein_start="2415"
                     /score="19.0"
                     /tool="antismash"
                     /translation="ALNICITSHIKGTPDATIFKAALDELKRRNEMLRTAY"
     CDS_motif       8509..8571
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0017"
                     /evalue="1.40E-08"
                     /label="C5_LCL_267-296"
                     /locus_tag="glpks3"
                     /protein_end="2691"
                     /protein_start="2670"
                     /score="27.2"
                     /tool="antismash"
                     /translation="NRPRSDLEDVLGFFVNMIPVR"
     CDS_motif       8629..8742
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glpks3_0018"
                     /evalue="1.70E-06"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="glpks3"
                     /protein_end="2748"
                     /protein_start="2710"
                     /score="20.3"
                     /tool="antismash"
                     /translation="ATVEAIEHSKIPFDTIVEAVNLPKSHSIFPISQVVVNY"
     gene            9546..12209
                     /gene="glnrps7"
                     /operon="glpks3/glnrps7"
     CDS             9546..12209
                     /NRPS_PKS="Domain: AMP-binding (8-246). E-value: 1.7e-50.
                     Score: 163.6. Matches aSDomain:
                     nrpspksdomains_glnrps7_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (383-448). E-value: 9.1e-13. Score:
                     40.1. Matches aSDomain: nrpspksdomains_glnrps7_PCP.1"
                     /NRPS_PKS="Domain: TD (504-765). E-value: 2.3e-41. Score:
                     133.5. Matches aSDomain: nrpspksdomains_glnrps7_TD.1"
                     /codon_start=1
                     /gene="glnrps7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     177.8; E-value: 4.7e-54)"
                     /gene_kind="biosynthetic"
                     /note="nonribosomal peptide synthetase"
                     /operon="glpks3/glnrps7"
                     /product="GLNRPS7"
                     /protein_id="AKL78825.1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-60, bitscore:
                     190.4, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.9e-14, bitscore:
                     38.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.3e-35, bitscore:
                     108.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLSTLQHDYSFTSNDKFLHQSSMCFDLSIVQIFSALTSGATVCIA
                     STPVRKDPARLAKFIQEAGVTVTYFTPTHFALLMESSADLFRLCSDYRIAFFAGERLSA
                     RVVDKFRALKTPAMILNTWSPSELVVQTTIHEVAESETGDVNIPIGFPMANCRHYILDT
                     QMNPLPAGLVGEICVGGSQVGSGYLNRPEANAASFVQDPFCSADDISRGWTRLFRTGDK
                     GRFLADGKLEFHGRIAGDKQIKLRGFRVDLGEVEHRIHLEASKLTGPKLVDISMVARTL
                     DGKESYTDERQLIAYIVLNSQIAPKEQVKYVTTIHKAIAKDLNPYMLPNGYQFLTELPM
                     TIGRKVDRQSLLTRELTLVYPSSKSNEPAAETNLGGDQQKVLDTIFQLYRDVLKLPKDR
                     EIGVTDNFFELGGQSILLLRLQAKLKRTYKKATPSLPELFKAPTPLAICQKICGLAATP
                     AAGASKAAAAAVKQIINWTAEATLPSDKRYLVRYGASTLSSSDITSVLLTGVESFIGLH
                     VFANMLSLEPTKHFHLLGSEKSIQVDDVIADLKQYKLLKGTVTEELVRSQTNIVPGSLM
                     QPGLGLEKTTFSQLGRSIQAIYHLGGRMSLLKNYETLRRANAGATMDLIELAASGLHRT
                     ELHYLSTWSVPHLQSHAAAKRNRTHIDISESSPDHFTPSEDAELFYFKSRWVSEMLLTH
                     AAERGFNVSIIRASAVSGSTATNVPAPDDDFVRRMIVDMVTLGSVPDLHGPAGTPAYAI
                     DFIPVNYLSSALQSLTTSDALRDEKSFTKKNLSIFHIGNPSPMNLHDLPKLMTQLRVDE
                     KEGKLVSLPDWLAEMKAKAKTEGDVLRWEAVKNVCETGHLMFALDQTETQKALEEVDSE
                     LTCPPMDKAFLKMLGA"
     aSDomain        9570..10283
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glnrps7_AMP-binding.1"
                     /evalue="1.70E-50"
                     /label="glnrps7_AMP-binding.1"
                     /locus_tag="glnrps7"
                     /protein_end="246"
                     /protein_start="8"
                     /score="163.6"
                     /tool="antismash"
                     /translation="YSFTSNDKFLHQSSMCFDLSIVQIFSALTSGATVCIASTPVRKDP
                     ARLAKFIQEAGVTVTYFTPTHFALLMESSADLFRLCSDYRIAFFAGERLSARVVDKFRA
                     LKTPAMILNTWSPSELVVQTTIHEVAESETGDVNIPIGFPMANCRHYILDTQMNPLPAG
                     LVGEICVGGSQVGSGYLNRPEANAASFVQDPFCSADDISRGWTRLFRTGDKGRFLADGK
                     LEFHGRIAGDKQIKLR"
     aSModule        9570..11840
                     /complete
                     /domains="nrpspksdomains_glnrps7_AMP-binding.1"
                     /domains="nrpspksdomains_glnrps7_PCP.1"
                     /domains="nrpspksdomains_glnrps7_TD.1"
                     /final_module
                     /locus_tags="glnrps7"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10050..10139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glnrps7_0001"
                     /evalue="3.30E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="glnrps7"
                     /protein_end="198"
                     /protein_start="168"
                     /score="41.8"
                     /tool="antismash"
                     /translation="PAGLVGEICVGGSQVGSGYLNRPEANAASF"
     CDS_motif       10263..10313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_glnrps7_0002"
                     /evalue="4.10E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="glnrps7"
                     /protein_end="256"
                     /protein_start="239"
                     /score="22.4"
                     /tool="antismash"
                     /translation="DKQIKLRGFRVDLGEVE"
     aSDomain        10695..10889
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glnrps7_PCP.1"
                     /evalue="9.10E-13"
                     /label="glnrps7_PCP.1"
                     /locus_tag="glnrps7"
                     /protein_end="448"
                     /protein_start="383"
                     /score="40.1"
                     /tool="antismash"
                     /translation="TIFQLYRDVLKLPKDREIGVTDNFFELGGQSILLLRLQAKLKRTY
                     KKATPSLPELFKAPTPLAIC"
     aSDomain        11058..11840
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_glnrps7_TD.1"
                     /evalue="2.30E-41"
                     /label="glnrps7_TD.1"
                     /locus_tag="glnrps7"
                     /protein_end="765"
                     /protein_start="504"
                     /score="133.5"
                     /tool="antismash"
                     /translation="VLLTGVESFIGLHVFANMLSLEPTKHFHLLGSEKSIQVDDVIADL
                     KQYKLLKGTVTEELVRSQTNIVPGSLMQPGLGLEKTTFSQLGRSIQAIYHLGGRMSLLK
                     NYETLRRANAGATMDLIELAASGLHRTELHYLSTWSVPHLQSHAAAKRNRTHIDISESS
                     PDHFTPSEDAELFYFKSRWVSEMLLTHAAERGFNVSIIRASAVSGSTATNVPAPDDDFV
                     RRMIVDMVTLGSVPDLHGPAGTPAYAIDFIPVNYLSSAL"
ORIGIN
        1 acccatttta catggacaac acctttacag caatatctgt acggtattgc tggagccaca
       61 cttgcagcta tcttgcagta atttctgtag gcagtatgca actgtcagag cgtggccacc
      121 ttgttccgtg ggagccgtcc acatggcgtc gagtcgagct agagcagcac tcccaccctg
      181 aagcacatgg cataagatta tcgagttctg agcctcagct tcataccgtg actgcgttga
      241 attccggagc atatggacgt ttaccgatac accagcctcg tcatgcgaat ctttctcagc
      301 agtactcata catataccat gagtacctac ctcttccttc actcttcagc aaagccgaca
      361 atcaagagtc ctgtgctaga tatacataac tgttcttaag tgatccagct atcttccagc
      421 cttccaagac tcattcttct gtcattcttt gccatcgact tttcggattc atccttaatc
      481 ttcccaaaat caatcaacat gtcggccctc gccccccaat tggtttccag gatgcaatcc
      541 tacgattctc gagtttccat cgatggactc tctgatgcca acctccaatc tggtaacacc
      601 tccactgacg caacctcggt ctcttcccaa gaagaggttg cccatgtgcc ggaaaacacc
      661 gcgattgttg gtatggcatg ccgtctcccg ggagcgaaga gcccacagca gctttggaag
      721 aacattgttg atcaacgtga tgtccaacgc aaaattccaa aggaaagatt caacgtcgac
      781 gctttctacc acccagaggg taccaacaag ggcactacca atgcccgata tggttacttc
      841 ctcgacgatg atgttagcga attcgaccct gaatttttcc agatctctgg taaggaggct
      901 gaggctatgg atccccagca aagacttctt ctagaggttg tatatgaggc attagagaat
      961 gctggtatta ctcttgatga aatcagtggc accgagacct ctgttttctg cggttccttc
     1021 accaacgatt accgtgagat gatccacaag gatttagaac attaccccaa gtacagcgtc
     1081 actggtactg gtgccgcaat tctggcaaac agaatttcct acttctacaa ccttcacggt
     1141 cccagtgtca ctctcgacac tgcttgttct tcctcgcttg tgggtcttca catgggaaac
     1201 cagagcatta gagatggtga ggcagatatc tctatcgttg ttggttccgc ccttcacttc
     1261 gatcctacta tctacactac catgactgat ctcggtttcc tctctgtcga cggtcgttgc
     1321 agagcttttg atgccggtgg atctggatac gtccgtggtg agggtatctg tgctgtcatc
     1381 ttgaagcgca agtcgcaagc tcagatggac ggaaacaata tcagagccat catccgaggc
     1441 acaggttgca accacgatgg tatcaaggag ggtattacta tgcccaattc tgtcgcccag
     1501 gaggctttga tccgaagagt ttacaagaac accggtctca acaccaacga gacccaatac
     1561 tttgaagccc acggtaccgg aacccaagct ggtgatcctc gtgagacccg cgccattggt
     1621 gctgtcttcg ctcctaaccg cgatcgtcct ctctacgtcg gttcagtcaa gaccaacatt
     1681 ggtcatttgg agggtgcatc tggtcttgca ggtgttatca aaactaccat gtctcttgag
     1741 gctggcaaga ttctccctaa catgcttttc aacaacccca atccaaagat cgacttcgag
     1801 caatggaaaa tcactgtccc aacgaagatc atcgactggg aaccaaccaa cggtgtccgc
     1861 cgtgcctccg ttaactcttt cggatatggt ggaaccaacg cccacatcat tcttgaaggt
     1921 tacaacaagc cagccgttgt tgaggaggtc gtcaaactca ttcctgagta cgaggagatg
     1981 gtctccgaac gaccattctt gcttcctctt acttctcaca ctgagaaagc cggtaacctt
     2041 ctcaaaaaca acttgtcaac attcattgct ggcgagaatg tttccgcccc tgatgctgcc
     2101 ctcagtctca gcaaccctgg acgttcaaac caccaataca gatcctatgt tattggtcag
     2161 gattctgacg agatgatcga gaaacttagc accaccactg gaggaactcc ttggactcgt
     2221 gccaccaaga ccaagccaag aattggttac gttttcactg gtcaaggtgc tcaacattac
     2281 cacatgggta gagaactcct tgaaaagtgc ccaatgttca agcagtcgat ccagaagtgt
     2341 gacgagatcc tccaaagtct cgaggcacca ccatcctgga gcgttctcac tgagttgatg
     2401 aagagcaagg aagattcttt ggttaacggt atcgagttct cttcttcgct cgccactgcc
     2461 attcagttgt ctactatcga tctcctccgc gcatggggtg tcgagcctgc tgctgtctgc
     2521 ggtcactccg ccggtgaaat cccagcttct tatgctgctg gtatcctctc tttcaaggat
     2581 gctctcgcct gcgcttacta ccgtggttgt gccttgtctg gtgagccaga ggacaaggtt
     2641 cagattccag gagccatggt tgctgttggc atgactgaat ctgaggctat tgttgagctc
     2701 gagaaatatg gtggagctgt caagatcgct gccgtcaaca gtcctaccag tttgactctt
     2761 tccggggacg agccacaagt tgtcgagctc cagaagtctt tggaggaccg aaaggtcttt
     2821 gcacgtcgtc ttgcagtcga gcgagcctac cactcccacc acatcgctcc ttacgcacca
     2881 gagctcactc gcctctcccg caacgttcga ccacgtcctg ctacctgccg tatgttctca
     2941 agtgtcactg ctcgtatcgc tgaatggcag aagatgaccg gcgcttacta cgcccttaac
     3001 ttggtcaacc aagttagatt ttctgatgcc ttgaccggta ttctcattga cgagaacgag
     3061 gagcaaaacg tcgacgtctt gattgaaatc ggtgctcacc cagctctcaa gggtccttcc
     3121 agacaaacta ttcaagcctt gaagctcgat gtcccatact tggccacaat tgctcgtggt
     3181 gctaacgatt tcgagggaat gcttgcaacc gtcggacagc tttacgccat gggataccca
     3241 gttgatttgg aagctgtcaa cagcgacctc ttcctcggta gcgatggagc cgttgtccgc
     3301 gctccagctg gcaagactgt tgatctacca agctactctt gggatcacag caaatactgg
     3361 gccgagacca gactcgtcaa gagctaccgc aaccgtgccc accgccattc aatcctcggt
     3421 gcacctatgc tcggtaacct cgagaagcac ccaagatgga gatctttcct ccgaccaaga
     3481 gagcttcagt ggcttcctca ccacatgatc gacggcaagg taattttccc agctgctggt
     3541 tatcttacaa tggccatcga agctgctgtc cgtctcgaga catgccccaa gaacatcaag
     3601 gctatctgtc tccgtgatat cgctatcaag tctgctctta ctgtttctga cagcgagatg
     3661 ggtactgaag ttatctttga gatgcagcct gtctctactt cagccaagcg cacttcagac
     3721 acctggtaca gattcattat caactcattc ggagataacg gtgttgtcaa cgagcactgt
     3781 tacggtttga tctccgtcga ggctggtgac tccactgcca ttgagactga taccccagct
     3841 ccatctctcg ctcagctccg caaacgaagt gacagatgca ccacttccaa gaccttctat
     3901 gagcacttgt ggaacattgg tcttcaatac ggtgaagact tccagctgat caccggaaac
     3961 gttgacagtg gatctggata ctctatggca ccaatctctc tcaagccagc tgctttgatg
     4021 accactccta acgatcactg tgtcattcac ccatcgttcc tcgatgcctc attccatcca
     4081 ttctttgctg gtattgagtc gttgttgggt agacctcttg acggtccttt cgtgccaacc
     4141 ttcatgaaat acctcaagct ttccggtgct ttcttcgatc tcacccaagg cactgctgag
     4201 cacactctgt gggctaccgc tgagacaaag ctcccaggtc cacgtgtcgc tatctccgac
     4261 atcacagttc gttccgctga ttgcagtgaa attctgattg atatgcaagg tcttgaggct
     4321 actgctcttg gttcctcgac tgctgagact tctcgccagc tcttcttcag aactcgatgg
     4381 caaccagctt tcgataatct cgccggtacc gctgaactct cagccttgaa gacccctgct
     4441 gagattatgg atgtctacgc tcaccaatac ccagatacca agattctgca catcacatct
     4501 gatcttgctg ctaccaagga acttcttact accctcttcc ctcaacaacg ccgtcgtttc
     4561 cagagcatca ccccttactg tggttctgag gaacaatttg aggatattga ggccctcacc
     4621 aaggtttact ctaccttgat tgatactgct gagccaaaag aaggtgctta cgacttggtt
     4681 gttgtcagca agactacttc tctcgacgtc aagtctttct tgaactctac tggacacgtc
     4741 attgtcgctg gtggtgagta tgatggccaa ggaatgagcg ttctgttcca gaactcctcc
     4801 ttcaccgcat acaccgaggc atacagctcc aactacaccg caaagccttt gacacttgtt
     4861 atgggcaaga aagtctctga gacaactgaa gcgctcgctc aactgatcac cagcaagcag
     4921 actgcacctg tcactcgcat gtcgtttgtt gacatggttg agaacgctcc agcaaccgag
     4981 aacgttattg ttcttgccag tttggaccaa gagctcttct tcgaggaccc agagcacgag
     5041 gagattcact tcgaggcagt ccgaactttc ttcaccagtg agaacaagaa cattgtttgg
     5101 atcgttcgtg gtgcttccca ggagacctcc aaccctgctc aagccatgat tctcggtatg
     5161 tgcagagtcg cccgtaacga gaacgacaaa ctcaaggttg ttaccctcga tgttgccgag
     5221 actgcccaga atggccagat tgctgagcag atcaacacaa tcctcgacag ccgcttgact
     5281 gaggatgagt atgctgctcg caacggcact ctctcgatcc caaagattga gaccgatgac
     5341 cttctcaaca acaagctccc agagaactcc ggtggtgatg ctgttatgca ggaattcggt
     5401 gctggtcaac ccctcgcact caagattggc aaagtcggtc ttttggagac tttggctttc
     5461 ggagttgatg aggacattgt cgacactgag cttgctgccg actccatcga ggtcgaggtc
     5521 aaggcttccg ccatcaactt ccgtgatgtt gccgcttcta tcggtatcat tgacgattac
     5581 agacttggtg atgagtgcgc tggtgttgtt ctccgcatcg gaagtgctgt caaccctaac
     5641 gacttccaag ttggcgaccg tgtcgttgct ttcagacctg gacaaggtgc tcacagatcc
     5701 atcgtccgcg aacaagctgc tctctgctac aaactcccgg agaacatctc attcaccact
     5761 gctgctgctt tcacctgcat catgatcacc gcatactatg cattccacga tcttgctcgc
     5821 ctccaacctg gtgagaaggt cttgatccac gccgccgctg gtggtgtcgg tcaaatggct
     5881 atccaagttg cgcaaatgat gggtgctgaa gtcattgcca cctgtggaag ccaagccaag
     5941 cgcgacctcc tcaagtcgac ttatggtctt actgatgacc acatcttctc ttctcgtgat
     6001 ccttcattcg tggctgatat caaccgcctc accaacggca agggtgtaga tgttgttctc
     6061 aactctctcg ctggtgatct tctccatgcc acctgggcct gtgttgctcg attcggtcgc
     6121 ttcattgaaa tcggaaagcg tgacatccac gagaatgcta agattgatat ggagcctttc
     6181 cgcaagagtg tcggattcgc ttctctcgat ctcatcacca tgtacgagta caacaagcct
     6241 ctatcccacc gcctcctcaa cgaaacctac aagctacttg agcagggcaa gatcaacaac
     6301 ccacactctg tccttgagct tccttactct gaggctgaga agggtttccg tctcttgcaa
     6361 atgggcaagc acactggtaa gattgtcttg gtaccacaca aggatgacat cgttccagtc
     6421 tctctcccat cttaccgcaa gacaatgttg ttcagcccag agaagtctta cctcctttct
     6481 ggtggtcttg gtggtcttgg ccgtacaatg gccgagtgga tggtgcgaaa gggtgcccgc
     6541 caacttgctt tcttgtctcg ttcaggagat gctcgcccag aagcaaaggc cactgtcgaa
     6601 tggctccaag ctcgtgacat caaggtcaca atcttcaagg ttgatgtctc tgactacgct
     6661 gctgttacca aggctgtcca atcccttggc gacaaccttg ctggtatctt ccatgctgcc
     6721 gtcgttcttc aagatgctcc tttgaacacc atgtctctca agcaatggca aggatgtgtt
     6781 caccctaagg ttcagggtgc ctggaacttg caccgcgcta ccctccactt ggatctcgac
     6841 ttcttcactc ctttctcttc cgtcgcttgc caggtcggag ctatggggca gaccaactat
     6901 gccgctgcta acacctacct cgatgccctt gtccgttacc gtcgctcaat tggcctcaag
     6961 gcatcttcca tgaactgtgg tatgattgtt ggtgttggac ttgtcgctga gaacgaatcc
     7021 attctcaact ggctcatcaa gatgggttct gacggtgtca acgaggacga acttctctac
     7081 cagattgagg aagccgtcgt tggcggctca gctccaactc aactcactgc cagaggtatc
     7141 gaccctgctg ctaccactac cggtgttcaa actgcccgca atgatgttta ctggcacgga
     7201 cgtgccttct tccgcaactt gtactccaac ttcgatgttg caggagctgg tgccgctaag
     7261 ggaggcaact ctcttggtgc attgcttcaa gcagctaagg atgttccaga gagagctcaa
     7321 atcttaactg aagccttcat tgagaagatc gccgctgttc ttggtgttgt tgccgagacc
     7381 atccagccag ggaacccact ttccatgtac ggtctcgact ccattgtcgc tgtcgagttc
     7441 cgaaagtggt tctccaagac catcaacgtc gatattgctt tgttcgacat cttgtccagc
     7501 aagtccatcg ctctccttgt cttgaaggca gctagcttga tggtcattga agttgccgcg
     7561 tcggagaaat ctaagggctc ttctgaggag accaagggaa gtgctgctgt ttctgagcaa
     7621 gccactgctg gtgagcaatc atctgacttt gatgctatct caatcgcccg cccaagcaac
     7681 atcccaatgt ctaccttcca gcgccgtatg tggtacgcac acaacttggt tgaggacaag
     7741 tctgctctca acatctgcat cacctcccac atcaagggta cacctgatgc cactatcttc
     7801 aaggctgctc tggacgagct caagcgccgc aacgaaatgc tccgaactgc ctacagtgaa
     7861 ggagatgatt ttgctgagca agagccagtt gctgactttg actctcgcct tgtctacaga
     7921 gatctctcta ctgagatcga tgttgatgca tccctcgaat catggagagc atctcttcaa
     7981 ggtgaggagc ttgacattga gaatggtgag atcatgcgac caggactctt caagcttggt
     8041 gatgagaaat ttgccttcgt tgtcgcattc caccacatct ccatcgatcg tggatcttcc
     8101 aaggctctgt tcgagcaatt cgtcgagatc tacgacgcta tccgcttgga gaaggatctc
     8161 gcatccgtgg caccaccaag aatctcttac accgatttct caatctggta cgagaaccac
     8221 cttcgcagtg caggactcca gtccgaggtt gagttctgga agcaaagatt ggctggcatc
     8281 aagccaacat ctgaacttct gccattcgcc aagaccactc gtccagatac catggacaga
     8341 gtccgcgacg agctccgatc aactcttcca ctttctatgc tcctccgtct caagcgtgtt
     8401 tgcgctcgca tgggcactac tcctttccaa tttatgcttg ctgctttccg cgccttcctt
     8461 ttccgttaca ctgaggagga ggatgttact gtcttggtca tcgatggtaa cagacctcgc
     8521 tccgatcttg aggatgttct tggattcttc gttaacatga ttcctgtccg actcaacaac
     8581 gttgacagtg actccctctt cgactctgta cttagctcca ctaaatccgc cactgtcgaa
     8641 gctatcgagc acagcaagat tccattcgac actattgtcg aagctgtcaa cctcccaaag
     8701 agccacagca tcttccctat ctcacaagtc gttgttaact accagatgca cggtaagatg
     8761 ccgcgattcg gaaccgagga tttccacatc cacactgtca tcaatcacga tatccctact
     8821 gcctgcgagc ttgctcttga ggctcttgag gatcctgaca agggattgga cctccgtctc
     8881 gagtactcca ccactctcta tgctgaggcc gatatggaac gcttcttcga taacttcagc
     8941 acattcttga ccagcttgat ccgcgaccac agacaaccaa tcgctcagac ccaaatgact
     9001 ggcccaaaag aagtcgagca tctcaagact aactactgga acatgggatt caccgagaac
     9061 acctggaagg gtgcttcagt cgtcgagaag atcctcaaga aggctgaaga gacccctgat
     9121 gctttagcca tccagaccgc tgagaatggt aacctcacct acaagcaact agtggaccag
     9181 gcacagcgca tcgcagctac tctggaacaa gcgaacattg cgccaggtac atctgtcggt
     9241 gtattggcct cgccaggagc cgatgccgtt gtggccatgg ttggtgccct catccgcgga
     9301 tgtggatacc tcgcaatgga ccctgaattc gcagcgcaaa gattaagctt catggcttcg
     9361 gactcggctg tcaaactcat acttgttgga gaagatctcg agagcgttgg atgtgcggtg
     9421 gcggcgaaga ccacctcacc accgcaagtc atgccaattg ccgttgctaa gagtagcaac
     9481 gagaagtcaa gggtagcaca ggtatcccga aaggcgtagt gttgagtcaa tcaaacactc
     9541 aacagatgct ttctacactt cagcatgatt attcctttac ttctaacgac aaattccttc
     9601 accaatcttc aatgtgtttc gatctctcta ttgttcaaat attttccgct ctcacatctg
     9661 gcgcaacggt ttgcattgct tctacacctg ttcgaaaaga cccggctcgt ctcgccaaat
     9721 tcatccaaga agccggcgtc acagttactt attttacacc cactcatttc gccttactca
     9781 tggaatcatc cgccgacctc ttcaggcttt gctctgacta tagaattgct ttctttgcag
     9841 gagaacgtct ttctgctcga gttgtcgaca agtttcgtgc tctgaaaact ccagctatga
     9901 tcctcaacac atggagtcct agtgagcttg tcgtccagac aactattcac gaggttgctg
     9961 aatcggaaac cggcgatgtc aacattccaa ttggctttcc aatggccaac tgtcgtcact
    10021 acatcctcga cacccaaatg aacccactcc cagcaggact ggtcggagag atctgtgtcg
    10081 gtggttctca agtcggttcc ggttatctca accgcccaga agccaatgca gcatcattcg
    10141 tacaggatcc tttctgttct gctgatgata tctctcgggg ttggactcga ctcttcagaa
    10201 ccggcgacaa aggtcgattc ctagctgatg gaaagctcga gtttcatggt cgtatcgctg
    10261 gtgacaaaca gatcaagttg agaggtttca gagtcgatct tggcgaagtc gagcatcgta
    10321 ttcatctcga agcttccaag ctgaccggcc ccaaacttgt cgatatctca atggtcgcac
    10381 gaactctgga tggcaaggaa agctacaccg acgagcgcca attgatcgct tacattgttt
    10441 tgaattctca aatcgctcca aaagagcaag tcaaatatgt cacgaccatt cacaaggcga
    10501 tcgccaaaga cctcaaccct tacatgttac ctaatggtta ccaatttctc actgagcttc
    10561 caatgaccat tgggcgaaag gttgacagac aaagcctact tacaagagaa ttgactcttg
    10621 tctatccttc ttccaagtca aatgagcctg ccgccgagac caacttgggc ggtgatcaac
    10681 aaaaggtcct tgacacaata ttccaactct atcgcgatgt tctcaagctt ccaaaagacc
    10741 gcgagattgg tgtaactgac aatttctttg agcttggagg tcaaagcatt cttttactca
    10801 gacttcaagc caagctcaag cgcacctaca agaaagcaac tccatcattg cctgagctgt
    10861 tcaaagctcc aactcctctt gctatctgcc aaaagatttg tggacttgca gcaacacctg
    10921 ctgcgggcgc aagcaaagcc gcagctgcag ctgttaaaca aatcatcaac tggaccgcag
    10981 aagctactct accttcggac aaacgatatc tcgtcagata tggagctagc actctcagct
    11041 cctccgatat cacttctgtc ttgctcactg gtgttgagtc tttcatcggt cttcatgtct
    11101 ttgcaaacat gctctccttg gagcccacaa aacatttcca ccttcttggt tctgagaagt
    11161 caatccaggt tgacgatgtc atcgccgacc tcaaacaata caagctcctc aaaggcacgg
    11221 ttaccgagga actcgtccgc agtcaaacca atatcgttcc aggaagcttg atgcagcctg
    11281 gccttggtct tgaaaagacc acattcagtc agctcggccg ttcgatccaa gcaatatatc
    11341 atctcggcgg tcgcatgtca cttctcaaga attacgagac cctccgccga gccaacgctg
    11401 gcgcaaccat ggacttgatc gagcttgcag cttcgggtct tcatcgcact gaactccact
    11461 acttgtccac atggtctgtt cctcatcttc aatctcatgc agcggccaaa cgaaaccgca
    11521 cacacatcga tatcagtgaa agctctccag atcacttcac tccttccgag gatgccgagc
    11581 tcttctactt caaatcccgc tgggtgtcgg agatgctact cactcatgca gctgagcgag
    11641 gcttcaacgt atccatcatt cgtgcatcag ccgtttccgg cagcaccgca acaaatgtac
    11701 cagctcctga cgatgacttc gtccgccgca tgatagtcga catggtcact ctaggaagtg
    11761 tacccgatct ccacggccct gctggcactc cagcatatgc catcgacttc atccctgtca
    11821 actacttgtc atcagccctg caatcactca caacatccga tgcactccgc gatgaaaaat
    11881 cattcacaaa gaaaaaccta tcaatcttcc acattggcaa tccatcgcca atgaatctcc
    11941 acgatctacc caagctcatg actcaactgc gagtcgacga aaaagaaggc aagctcgtca
    12001 gtcttccgga ctggctggca gaaatgaaag caaaggcgaa gacagagggt gatgtcttga
    12061 gatgggaagc tgtcaagaat gtctgcgaga caggccatct gatgttcgcg cttgatcaga
    12121 ctgaaacgca aaaggcgctc gaggaggtgg attccgagct cacatgtcca cccatggaca
    12181 aagcattctt gaagatgttg ggtgcttaat tccatgttca acttcctagt cagatctcct
    12241 tacacctttt atgtatttcg gagttgggag tttatgggat ttgtttttaa tgtctcagcc
    12301 cttgtgggct cttgaaggta tctctagctg agttgggaag cgacgcttga gatggtggat
    12361 tgtgcctgtt ctggctttgg ctctggttct aaaaaagatc ttgtggctct cttcttgctg
    12421 agttggtagc gatgcgaggg gtgggctact tggtcctaat tactgtattt tagcgattgt
    12481 gggatttgaa ttttgggctt ttttcataga tttcctttgc atatagatat atctctataa
    12541 aataaaaatt tctcttctta cg
//
