BGC0001192: colistin A biosynthetic gene cluster from Paenibacillus alvei
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Location: 1 - 41,172 nt. (total: 41,172 nt).
This entry is originally from NCBI GenBank KP262070.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001192
Short description colistin A biosynthetic gene cluster from Paenibacillus alvei
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: KP262070.1
Compounds
  • colistin A
  • colistin B
Species Paenibacillus alvei [taxonomy]
References
Chemical products information
colistin A
Copy SMILES
C53H100N16O13
Chemical database entries
PubCHEM
colistin B
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C52H98N16O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AJM89735.1
1 - 14997 (+) PmxA
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  • AJM89734.1
15150 - 18458 (+) PmxB
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  • AJM89736.1
18448 - 20274 (+) PmxC
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  • AJM89737.1
20271 - 22004 (+) PmxD
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  • AJM89738.1
22294 - 41172 (+) PmxE
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
AJM89734.1
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
AJM89735.1
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
AJM89738.1
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Module ?
Specificity: 2,4-diaminobutyric acid
Evidence for specificity:
  • Structure-based inference
  • Sequence-based prediction
Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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