BGC0001220: aculeacin A biosynthetic gene cluster from Aspergillus japonicus
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Location: 1,840,826 - 1,901,106 nt. (total: 60,281 nt).
This entry is originally from NCBI GenBank NW_017962980.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001220
Short description aculeacin A biosynthetic gene cluster from Aspergillus japonicus
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NW_017962980.1
Compounds
  • aculeacin A
Species Aspergillus japonicus [taxonomy]
References
Chemical products information
aculeacin A
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C50H81N7O16
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ASPACDRAFT_51502
  • XP_020058092.1
1841725 - 1843474 (+) uncharacterized protein
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  • ASPACDRAFT_42018
  • XP_020058093.1
1844623 - 1845763 (+) uncharacterized protein
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  • ASPACDRAFT_26446
  • XP_020058094.1
1846238 - 1848027 (-) uncharacterized protein
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  • ASPACDRAFT_51504
  • XP_020058095.1
1848716 - 1850129 (+) uncharacterized protein
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  • ASPACDRAFT_2707
  • XP_020058096.1
1850997 - >1853456 (+) uncharacterized protein
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  • ASPACDRAFT_42022
  • XP_020058097.1
1853742 - 1854287 (-) uncharacterized protein
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  • ASPACDRAFT_77431
  • XP_020058098.1
1855688 - 1856705 (+) uncharacterized protein
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  • ASPACDRAFT_4483
  • XP_020058099.1
1856873 - >1858613 (-) uncharacterized protein
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  • ASPACDRAFT_42025
  • XP_020058100.1
1859951 - 1882030 (+) uncharacterized protein
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  • ASPACDRAFT_77432
  • XP_020058101.1
1882421 - 1883595 (+) uncharacterized protein
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  • ASPACDRAFT_42027
  • XP_020058102.1
1884114 - 1885862 (+) uncharacterized protein
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  • ASPACDRAFT_42028
  • XP_020058103.1
1886553 - 1888565 (-) uncharacterized protein
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  • ASPACDRAFT_42029
  • XP_020058104.1
1890798 - 1893088 (+) uncharacterized protein
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  • ASPACDRAFT_59413
  • XP_020058105.1
1893713 - 1894873 (-) uncharacterized protein
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  • ASPACDRAFT_25680
  • XP_020058106.1
1895323 - 1900629 (+) uncharacterized protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
ASPACDRAFT_42025
Module ?
Specificity: ornithine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 4R-hydroxyproline
Evidence for specificity:
  • Structure-based inference
  • Homology
  • In-vitro experiments
Module ?
Specificity: 3R-hydroxyhomotyrosine
Evidence for specificity:
  • Structure-based inference
  • Homology
  • In-vitro experiments
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: 3S-hydroxy-4S-methylproline
Evidence for specificity:
  • Structure-based inference
  • Homology
  • Knock-out studies
Annotation changelog
MIBiG version Submitter Notes
1.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Replaced locus with better representation from existing references
  • Added NRP substrate specificities
Detailed domain annotation
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