BGC0001252 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001252 (Alternaria alternata)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	T1PKS	1	7,958

BGC0001252 - Region 1 - T1PKS

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Location: 1 - 7,958 nt. (total: 7,958 nt) Show pHMM detection rules used

Region on contig edge.

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

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core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 7,959
Label		BGC0001252

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001252.1	0.55	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0000046.1	0.23	Polyketide	depudecin	Alternaria brassicicola
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001124.1	0.21	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001254.1	0.20	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000107.1	0.20	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001284.1	0.20	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.20	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000099.1	0.18	Polyketide	monascorubrin	Talaromyces marneffei
BGC0001244.1	0.18	Polyketide	(-)-Mellein	Parastagonospora nodorum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001252.1	0.82	Polyketide	UNII-YC2Q1O94PT	Alternaria alternata
BGC0000046.1	0.56	Polyketide	depudecin	Alternaria brassicicola
BGC0000056.1	0.56	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0001124.1	0.53	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001254.1	0.53	Polyketide	ACT-Toxin II	Alternaria alternata
BGC0000107.1	0.53	Polyketide	naphthopyrone	Aspergillus nidulans FGSC A4
BGC0001284.1	0.53	Terpene	alternariol	Parastagonospora nodorum SN15
BGC0001258.1	0.52	Polyketide	1,3,6,8-tetrahydroxynaphthalene	Glarea lozoyensis
BGC0000099.1	0.50	Polyketide	monascorubrin	Talaromyces marneffei
BGC0001244.1	0.50	Polyketide	(-)-Mellein	Parastagonospora nodorum

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 7958:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Me-pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ACRTS2

PKS_AT (546..873): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; Methylmalonyl-CoA: 62.5%; Ethylmalonyl-CoA: 58.3%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 74.7
Methoxymalonyl-CoA: 73.5
Malonyl-CoA: 67.3
Isobutyryl-CoA: 55.1
Propionyl-CoA: 44.8
Benzoyl-CoA: 34.4
Ethylmalonyl-CoA: 29.3
2-Methylbutyryl-CoA: 25.4
3-Methylbutyryl-CoA: 21.4
fatty_acid: 14.6
trans-1,2-CPDA: 8.9
inactive: 8.4
CHC-CoA: 5.4
Acetyl-CoA: 1.9