LOCUS       BGC0001443             24158 bp    DNA     linear   CON 06-MAR-2022
DEFINITION  Actinomadura atramentaria DSM 43919 strain SF2197
            G339DRAFT_scaffold00017.17, whole genome shotgun sequence.
ACCESSION   BGC0001443
VERSION     BGC0001443
KEYWORDS    .
SOURCE      Actinomadura atramentaria DSM 43919
  ORGANISM  Actinomadura atramentaria DSM 43919
            Bacteria; Actinobacteria; Streptosporangiales; Thermomonosporaceae;
            Actinomadura.
COMMENT     REFSEQ INFORMATION: The reference sequence is identical to
            KB907224.1.
            URL -- http://www.jgi.doe.gov
            JGI Project ID: 405907
            Source DNA and organism available from Hans-Peter Klenk at the
            German Collection of Microorganisms and Cell Cultures (DSMZ)
            (hans-peter.klenk@dsmz.de)
            Contacts: Nikos  Kyrpides (nckyrpides@lbl.gov)
            Tanja Woyke (microbe@cuba.jgi-psf.org)
            Whole genome sequencing and draft assembly at JGI-PGF
            Annotation by JGI-PGF and JGI-ORNL
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376)
            Full annotations are available from IMG.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-08 01:39:11
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1212)
                     /GO_function="GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA]"
                     /GO_process="GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]; GO:0015819 - lysine transport
                     [Evidence IEA]; GO:0015822 - ornithine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="meaB"
                     /inference="COORDINATES: protein motif:HMM:TIGR00750.1"
                     /locus_tag="G339_RS40700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylmalonyl Co-A mutase-associated GTPase MeaB"
                     /protein_id="WP_019634547.1"
                     /transl_table=11
                     /translation="MSLLDRARAGDRRAVSRLLTLLDAAGPGGHPAVAEALRRRDRALV
                     VGLTGPPGVGKSTLTSALIAEFRRRDRRVAVLCVDPSSPLTGGALLGDRIRMQRHVGDG
                     GVFVRSMASRGHLGGLSAGTPAAVRVMEAAGFDVVLVETVGVGQSEVEIAALADTTAVV
                     LAPGTGDAVQIAKAGVLEIGDVYVVNKADRPGAARIVRDLNAMTALNTASARPPVITTV
                     ATEDEGTAALVDELVARGIRRDGPTAVADVEYVEDEAALLALYGDAAAPAAHNGHSGLD
                     ARARDWLAAAALCLLATADAAGRCAVSPRGAARVLDDRTLVLPDGPGGRLDAHRDVLAN
                     PRVGLLFLVPGRRDALRVGGRARIVARAPYLAGLGADGEPAPSAIQVAVDEVVLYERWL
                     PDAF"
     protocluster    1..24158
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2544:7191]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2545..7191
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     protocluster    1..24158
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2544:7191]"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      2545..7191
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     cand_cluster    1..24158
                     /SMILES="NC(CC(C)C)C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="chemical_hybrid"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..24158
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0001443"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24158
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..1212)
                     /gene="meaB"
                     /locus_tag="G339_RS40700"
     gene            complement(1209..1616)
                     /locus_tag="G339_RS0128875"
     CDS             complement(1209..1616)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911485.1"
                     /locus_tag="G339_RS0128875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cobalamin B12-binding domain-containing protein"
                     /protein_id="WP_019634548.1"
                     /transl_table=11
                     /translation="MRRVRVVIAKPGLDGHDRGAKVVARALRDAGLEVIYTGLHQTPEQ
                     IVETAIQEGADAIGLSLLSGAHMTLVPRVLDLLAAADAADVAVFCGGIIPPDDIDALTG
                     LGIVRIFTPSSSVEEIIAWARAELRPLEVAE"
     gene            complement(1613..2548)
                     /locus_tag="G339_RS0128880"
     CDS             complement(1613..2548)
                     /NRPS_PKS="Domain: Thioesterase (78-296). E-value: 4.6e-46.
                     Score: 149.9. Matches aSDomain:
                     nrpspksdomains_G339_RS0128880_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 62.2; E-value:
                     4.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.2"
                     /locus_tag="G339_RS0128880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_019634549.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.2e-13, bitscore:
                     39.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVYDVVTNDEAEYGLWPAGRAAAPGWTPTGFQGSRRDCLDHVAR
                     VWTDMRPRSVRRGRSPGASRWLVRRRRRGDAALRLYCFPHSGGSPGEFVRWSDALTDVE
                     VLGLQLPGRGARLEEPPFTDMAALVAAVVEDVEFTGPYVLFGHSLGGWVAFETIRALQA
                     SGRPLPERLVVSATPPPHFRVERDPLHRMGDDDLLDAVEQRYGGLPPTLREDPDLLALV
                     LPAYRADFQIFEEYEHAPGDPIDVPITVVGGADDAMPADLLRAWDRHTARGADLHMLPG
                     GHFYLRDEPGRTRLLDLVRALAPGTKEADR"
     aSDomain        complement(1661..2314)
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128880_Thioesterase.1"
                     /evalue="4.60E-46"
                     /label="G339_RS0128880_Thioesterase.1"
                     /locus_tag="G339_RS0128880"
                     /protein_end="296"
                     /protein_start="78"
                     /score="149.9"
                     /tool="antismash"
                     /translation="RLYCFPHSGGSPGEFVRWSDALTDVEVLGLQLPGRGARLEEPPFT
                     DMAALVAAVVEDVEFTGPYVLFGHSLGGWVAFETIRALQASGRPLPERLVVSATPPPHF
                     RVERDPLHRMGDDDLLDAVEQRYGGLPPTLREDPDLLALVLPAYRADFQIFEEYEHAPG
                     DPIDVPITVVGGADDAMPADLLRAWDRHTARGADLHMLPGGHFYLRDEPGRTRLL"
     CDS_motif       complement(2069..2134)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128880_0001"
                     /evalue="3.30E-10"
                     /label="NRPS-te1"
                     /locus_tag="G339_RS0128880"
                     /protein_end="160"
                     /protein_start="138"
                     /score="32.3"
                     /tool="antismash"
                     /translation="TGPYVLFGHSLGGWVAFETIRA"
     gene            complement(2545..7191)
                     /locus_tag="G339_RS37205"
     CDS             complement(2545..7191)
                     /NRPS_PKS="Domain: AMP-binding (11-399). E-value: 4.9e-96.
                     Score: 313.6. Matches aSDomain:
                     nrpspksdomains_G339_RS37205_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (507-574). E-value: 1.5e-21. Score:
                     68.2. Matches aSDomain: nrpspksdomains_G339_RS37205_PCP.1"
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (596-1005). E-value:
                     2e-131. Score: 430.6. Matches aSDomain:
                     nrpspksdomains_G339_RS37205_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1099-1393). E-value: 3.2e-93.
                     Score: 304.2. Matches aSDomain:
                     nrpspksdomains_G339_RS37205_PKS_AT.1"
                     /NRPS_PKS="Domain: PCP (1475-1541). E-value: 9.2e-20.
                     Score: 62.5. Matches aSDomain:
                     nrpspksdomains_G339_RS37205_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 239.4; E-value:
                     1.2e-72)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="G339_RS37205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_019634550.1"
                     /sec_met_domain="AMP-binding (E-value: 8.9e-106, bitscore:
                     344.1, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     51.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 6.5e-132, bitscore:
                     430.6, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-93, bitscore: 304.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWTAVHRLLAARAAASPDSPAVRHGARTLTYGELDARSDRAAAL
                     LAGRGAAPGGVVGVLLPRGADLVVAEAAILKTGAAYAPADPRHPVERTAQAMTRAGAAL
                     VVTTAELADGLAARGLRPVLLDEVPADPVAAPPDRTRDRDVAMIVFTSGSTGAPKGVLL
                     EHGSLARFARWDADAFGLGPADRVALIASPGFDASAWDIWPTLAAGACLHAADEDTLLD
                     PRALRDWLVAERITVLFLTTALAERLLTLPWPADTALRTLLTGGERLKFRPPAGLPFQV
                     VNNYGPTETTIIATSGPVAAAGDGPPSIGAPLSIAAVHILDEDLRPVPDGEPGEIYIGG
                     TGVARGYLADPAQTVDRFPPDPFSGRPGARMYRSGDLGRRRPDGEIEFLGRVDDQVKIR
                     GNRVEPGEIAVVLTAHPAVTVAHVAPYTRPGDDETHLVAYVVGGPDDVGELRAYLAERL
                     PRALIPAYFVALDALPLNANGKVDRARLPEPDARRPAASAAHTPPRTGLERRLCALWAE
                     LLHLERVGIDDSFFDLGGHSLLLVEVHRTLTEDLGHDLPLVALFEAPTIRSLSDRLEPR
                     DAPAPAPVPASRPRGDSRALAVVGMAGRFPGAPSVAEFWANLCGGVDSIRVLAEGDGHL
                     DVHGVLDDADRFDAAFFGCPPSEALIMDPQHRVFLECAYHALEDAGHDPARFPGTIGLF
                     AGGATTEHLARLRAHRDRLPFVDAWQMRLGTGPDFLAARAADRLGLRGPVVSVQTACST
                     SLVAVHLAARAVLDGECDMALAGGATVHVPPPRGGYTPGGIISADGRLRAFDADARGAV
                     GGSAAALVALRPLEDALADGDHVHAVLLATAIGNDGGGKVGFTAPGVDGQVRVIRAALD
                     RAGVDPGTVTFVEAHGTGTPLGDLIEVRALTKALGPVAADAGGRALGSVKTNIGHTDAA
                     AGVSAFIKAALAVEHGLLPPTLHFDRPNPELDLDTGRFRVTTDLTKWETGGTPRRAGVN
                     ALGIGGTNAHAILEQPPVQPPADTGRGSQLLVVSARSPEALAELSSSLAAAVSARPSGS
                     LADIAWTLQDGRPAHPYRAFAVAGDAAAAARALTAPRPAPSGRTGEWPVVFMFPGQGGQ
                     HVGMARELYEQEPEFRRRFDRCADLALPGLGLDLREILFPPPERAADAERTLERISVGQ
                     PAVFAVEYALARLWTAWGITPAAVTGHSLGAYAAACVAGIIDLDDAVPLVVERGRLLES
                     LPTGTMLAVQLSEDEVAPLLPPALSVAAVNGPGRTTVTGAAADVARFHEELTARGVDSK
                     PLRIATAGHSPLVDRIRDEFEAAVRAVPLREPAVRFLSDRTGDWAAPAELTDPAYWSGH
                     MRDPVRFSAALSRLFAEPDAVLLEVGPGRTLATLARQHPERPASRVIAQSLPHPADDAS
                     ALDTALTALGRLWAEGIPVDWARVHEGERRRRVKLPLYPFQRRRFSLETSDADEPAPPP
                     APASAPEPRSTDAARMAEGFAVILGLDTVDRHDDFFELGGDSLIATRLAAWIRADRGVE
                     VTAREIYGAPTPARLADLVTGRAQEETR"
     aSDomain        complement(2569..2766)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS37205_PCP.2"
                     /evalue="9.20E-20"
                     /label="G339_RS37205_PCP.2"
                     /locus_tag="G339_RS37205"
                     /protein_end="1541"
                     /protein_start="1475"
                     /score="62.5"
                     /tool="antismash"
                     /translation="RMAEGFAVILGLDTVDRHDDFFELGGDSLIATRLAAWIRADRGVE
                     VTAREIYGAPTPARLADLVTG"
     aSModule        2569..5403
                     /complete
                     /domains="nrpspksdomains_G339_RS37205_PKS_KS.1"
                     /domains="nrpspksdomains_G339_RS37205_PKS_AT.1"
                     /domains="nrpspksdomains_G339_RS37205_PCP.2"
                     /locus_tags="G339_RS37205"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(3013..3894)
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS37205_PKS_AT.1"
                     /evalue="3.20E-93"
                     /label="G339_RS37205_PKS_AT.1"
                     /locus_tag="G339_RS37205"
                     /protein_end="1393"
                     /protein_start="1099"
                     /score="304.2"
                     /specificity="consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGQGGQHVGMARELYEQEPEFRRRFDRCADLALPGLGLDLREI
                     LFPPPERAADAERTLERISVGQPAVFAVEYALARLWTAWGITPAAVTGHSLGAYAAACV
                     AGIIDLDDAVPLVVERGRLLESLPTGTMLAVQLSEDEVAPLLPPALSVAAVNGPGRTTV
                     TGAAADVARFHEELTARGVDSKPLRIATAGHSPLVDRIRDEFEAAVRAVPLREPAVRFL
                     SDRTGDWAAPAELTDPAYWSGHMRDPVRFSAALSRLFAEPDAVLLEVGPGRTLATLARQ
                     HPERPASRVIAQS"
     CDS_motif       complement(3142..3177)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0012"
                     /evalue="2.40E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="G339_RS37205"
                     /protein_end="1350"
                     /protein_start="1338"
                     /score="14.5"
                     /tool="antismash"
                     /translation="YWSGHMRDPVRF"
     CDS_motif       complement(3523..3642)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0011"
                     /evalue="2.10E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="G339_RS37205"
                     /protein_end="1223"
                     /protein_start="1183"
                     /score="61.7"
                     /tool="antismash"
                     /translation="GITPAAVTGHSLGAYAAACVAGIIDLDDAVPLVVERGRLL"
     CDS_motif       complement(3649..3717)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0010"
                     /evalue="1.40E-06"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="G339_RS37205"
                     /protein_end="1181"
                     /protein_start="1158"
                     /score="21.0"
                     /tool="antismash"
                     /translation="LERISVGQPAVFAVEYALARLWT"
     CDS_motif       complement(3844..3900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0009"
                     /evalue="3.80E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="G339_RS37205"
                     /protein_end="1116"
                     /protein_start="1097"
                     /score="22.2"
                     /tool="antismash"
                     /translation="VFMFPGQGGQHVGMARELY"
     aSDomain        complement(4177..5403)
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS37205_PKS_KS.1"
                     /domain_subtype="Hybrid-KS"
                     /evalue="2.00E-131"
                     /label="G339_RS37205_PKS_KS.1"
                     /locus_tag="G339_RS37205"
                     /protein_end="1005"
                     /protein_start="596"
                     /score="430.6"
                     /tool="antismash"
                     /translation="AVVGMAGRFPGAPSVAEFWANLCGGVDSIRVLAEGDGHLDVHGVL
                     DDADRFDAAFFGCPPSEALIMDPQHRVFLECAYHALEDAGHDPARFPGTIGLFAGGATT
                     EHLARLRAHRDRLPFVDAWQMRLGTGPDFLAARAADRLGLRGPVVSVQTACSTSLVAVH
                     LAARAVLDGECDMALAGGATVHVPPPRGGYTPGGIISADGRLRAFDADARGAVGGSAAA
                     LVALRPLEDALADGDHVHAVLLATAIGNDGGGKVGFTAPGVDGQVRVIRAALDRAGVDP
                     GTVTFVEAHGTGTPLGDLIEVRALTKALGPVAADAGGRALGSVKTNIGHTDAAAGVSAF
                     IKAALAVEHGLLPPTLHFDRPNPELDLDTGRFRVTTDLTKWETGGTPRRAGVNALGIGG
                     TNAHAILEQP"
     CDS_motif       complement(4396..4440)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0008"
                     /evalue="7.10E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="G339_RS37205"
                     /protein_end="932"
                     /protein_start="917"
                     /score="12.0"
                     /tool="antismash"
                     /translation="GSVKTNIGHTDAAAG"
     CDS_motif       complement(4501..4548)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0007"
                     /evalue="9.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="G339_RS37205"
                     /protein_end="897"
                     /protein_start="881"
                     /score="11.6"
                     /tool="antismash"
                     /translation="FVEAHGTGTPLGDLIE"
     CDS_motif       complement(4921..4968)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0006"
                     /evalue="3.50E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="G339_RS37205"
                     /protein_end="757"
                     /protein_start="741"
                     /score="16.0"
                     /tool="antismash"
                     /translation="GPVVSVQTACSTSLVA"
     aSDomain        complement(5470..5670)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS37205_PCP.1"
                     /evalue="1.50E-21"
                     /label="G339_RS37205_PCP.1"
                     /locus_tag="G339_RS37205"
                     /protein_end="574"
                     /protein_start="507"
                     /score="68.2"
                     /tool="antismash"
                     /translation="ERRLCALWAELLHLERVGIDDSFFDLGGHSLLLVEVHRTLTEDLG
                     HDLPLVALFEAPTIRSLSDRLE"
     aSModule        5470..7158
                     /complete
                     /domains="nrpspksdomains_G339_RS37205_AMP-binding.1"
                     /domains="nrpspksdomains_G339_RS37205_PCP.1"
                     /locus_tags="G339_RS37205"
                     /monomer_pairings="leu -> leu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(5968..6030)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0005"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="G339_RS37205"
                     /protein_end="408"
                     /protein_start="387"
                     /score="35.3"
                     /tool="antismash"
                     /translation="FLGRVDDQVKIRGNRVEPGEI"
     aSDomain        complement(5995..7158)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS37205_AMP-binding.1"
                     /evalue="4.90E-96"
                     /label="G339_RS37205_AMP-binding.1"
                     /locus_tag="G339_RS37205"
                     /protein_end="399"
                     /protein_start="11"
                     /score="313.6"
                     /specificity="consensus: leu"
                     /tool="antismash"
                     /translation="ARAAASPDSPAVRHGARTLTYGELDARSDRAAALLAGRGAAPGGV
                     VGVLLPRGADLVVAEAAILKTGAAYAPADPRHPVERTAQAMTRAGAALVVTTAELADGL
                     AARGLRPVLLDEVPADPVAAPPDRTRDRDVAMIVFTSGSTGAPKGVLLEHGSLARFARW
                     DADAFGLGPADRVALIASPGFDASAWDIWPTLAAGACLHAADEDTLLDPRALRDWLVAE
                     RITVLFLTTALAERLLTLPWPADTALRTLLTGGERLKFRPPAGLPFQVVNNYGPTETTI
                     IATSGPVAAAGDGPPSIGAPLSIAAVHILDEDLRPVPDGEPGEIYIGGTGVARGYLADP
                     AQTVDRFPPDPFSGRPGARMYRSGDLGRRRPDGEIEFLGRVDDQVKIR"
     CDS_motif       complement(6118..6207)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0004"
                     /evalue="5.60E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="G339_RS37205"
                     /protein_end="358"
                     /protein_start="328"
                     /score="44.2"
                     /tool="antismash"
                     /translation="PDGEPGEIYIGGTGVARGYLADPAQTVDRF"
     CDS_motif       complement(6313..6342)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0003"
                     /evalue="3.70E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="G339_RS37205"
                     /protein_end="293"
                     /protein_start="283"
                     /score="10.0"
                     /tool="antismash"
                     /translation="NYGPTETTII"
     CDS_motif       complement(6697..6756)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0002"
                     /evalue="3.20E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="G339_RS37205"
                     /protein_end="165"
                     /protein_start="145"
                     /score="25.8"
                     /tool="antismash"
                     /translation="AMIVFTSGSTGAPKGVLLEH"
     misc_feature    complement(6859..6861)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(6937..6975)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS37205_0001"
                     /evalue="9.00E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="G339_RS37205"
                     /protein_end="85"
                     /protein_start="72"
                     /score="9.8"
                     /tool="antismash"
                     /translation="AILKTGAAYAPAD"
     gene            complement(7237..8847)
                     /locus_tag="G339_RS35690"
     CDS             complement(7237..8847)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 383.3; E-value:
                     2.1e-116)"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00711.1"
                     /locus_tag="G339_RS35690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_157408076.1"
                     /transl_table=11
                     /translation="MPDNSPPRHGAGAIVAVFGAAFLAMVDLSISAVAMPAIRDDLHAS
                     LSGLQWIFDCYTLAFAGLLMVGGTISDRLGHRTGLIASTALFTLGSVVCVAADGVWLLI
                     VGRSVQGAAAAMLVPASMAMISRLAPEPERKAKLLGAWGGLSGVAIALGPLLGGWFVHL
                     SGWRLIFGFNIAAGVLLLVLILAAAPKVVPGEGGSLDVPGLVLGVLWPTALAYSLIEGH
                     AQGWSAPGVLAGFVVGALALAVFVVVEVRAEHPMMPVRSFTSRVFAASNLVAAVLGFAL
                     SAAYYFLSLYIQQVLGHDALDAGFGFLPGALGLMFCAPLAGKLVKQVGARSLITGGLLL
                     GAVGLFGLSTLGADSGYWASWWAVALVGVGLGLALPANTTQALTSLPPERAGAASGTVE
                     TSMQLGTVLGIAVLGTVQATGFTGDLRDRLRGESVTGHALDRAVDDATASRPLRVPGVA
                     ADRLHDLVAGAFAHGLHLAFFTAFAVSAATGVIAFALLPRRSAADGPDAEAPEPPKVAV
                     DAGADTGADTGADTPNRDG"
     gene            complement(8894..9493)
                     /locus_tag="G339_RS0128895"
     CDS             complement(8894..9493)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024248.2"
                     /locus_tag="G339_RS0128895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_019634552.1"
                     /transl_table=11
                     /translation="MSDARPDGDNEELAGHPVRRDLLRLLRRDGVVTATTAARELGGSS
                     GLYSFHLRRLAQGGLIEEAPAGRGRVRPWRLATPPSPDAGGPDAGAAPPPEPGPVSDAC
                     LDLFARGLEDESFRRWLEHRDAAPARWRQDEAFSQVAYLTPEEMAGMARVIRALVAQYR
                     HRESRPDARPADAAPVAVVSRLFPLLEPGTEPAPPP"
     gene            complement(9546..10889)
                     /gene="ccrA"
                     /locus_tag="G339_RS0128900"
     CDS             complement(9546..10889)
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (49-407). E-value: 1.9e-27.
                     Score: 88.0. Matches aSDomain:
                     nrpspksdomains_G339_RS0128900_PKS_ER.1"
                     /codon_start=1
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 302; E-value: 8.2e-92)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653759.1"
                     /locus_tag="G339_RS0128900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_019634553.1"
                     /sec_met_domain="ADH_N (E-value: 9.7e-11, bitscore: 31.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.8e-29, bitscore:
                     92.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDALAEAVVAGEPADVLERIPVPDAYTAAHTRVQDAGMFRGVEDK
                     DVRKSLRVGEVPMPELAPDEALVAVMASAMNYNTVWSAIFEPLPTFAFLKSFGRQGGWA
                     TRHDQPHHVLGSDASGVIVRLGSGVRNWKVGDRVVVATNYVDDQDPATHADGMLGGDQR
                     AWGFETNFGGLAHYAVVRASQLLAKPEHLTWEEAACNPLCAATAYRMLVSDRGANMKQG
                     DLVLIWGAAGGLGGYAVQFARNGGATPIGIVSSDRKAEIARDLGCELVIDRRELGRIGS
                     DPDVVQSAGKKLGKIIRRECGEDPNIVFEHVGQATFGISVFVAARGGTVVTCGSSTGYD
                     HRFDNRYLWMRLKRIIGSHGANLQEQWETNRLVRRGKVASMLSAVYPLAEAPEAARGVQ
                     LNEHIGKVGVLCLAPRAGLGVADAALRERVGARGTAPLMVGGPLGAGR"
     aSDomain        complement(9669..10742)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128900_PKS_ER.1"
                     /evalue="1.90E-27"
                     /label="G339_RS0128900_PKS_ER.1"
                     /locus_tag="G339_RS0128900"
                     /protein_end="407"
                     /protein_start="49"
                     /score="88.0"
                     /tool="antismash"
                     /translation="SLRVGEVPMPELAPDEALVAVMASAMNYNTVWSAIFEPLPTFAFL
                     KSFGRQGGWATRHDQPHHVLGSDASGVIVRLGSGVRNWKVGDRVVVATNYVDDQDPATH
                     ADGMLGGDQRAWGFETNFGGLAHYAVVRASQLLAKPEHLTWEEAACNPLCAATAYRMLV
                     SDRGANMKQGDLVLIWGAAGGLGGYAVQFARNGGATPIGIVSSDRKAEIARDLGCELVI
                     DRRELGRIGSDPDVVQSAGKKLGKIIRRECGEDPNIVFEHVGQATFGISVFVAARGGTV
                     VTCGSSTGYDHRFDNRYLWMRLKRIIGSHGANLQEQWETNRLVRRGKVASMLSAVYPLA
                     EAPEAARGVQLNEHIGKV"
     CDS_motif       complement(9888..9908)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128900_0003"
                     /evalue="9.90E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="G339_RS0128900"
                     /protein_end="334"
                     /protein_start="327"
                     /score="-3.5"
                     /tool="antismash"
                     /translation="GTVVTCG"
     CDS_motif       complement(10164..10226)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128900_0002"
                     /evalue="7.10E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="G339_RS0128900"
                     /protein_end="242"
                     /protein_start="221"
                     /score="12.3"
                     /tool="antismash"
                     /translation="GDLVLIWGAAGGLGGYAVQFA"
     CDS_motif       complement(10512..10550)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128900_0001"
                     /evalue="7.70E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="G339_RS0128900"
                     /protein_end="126"
                     /protein_start="113"
                     /score="9.4"
                     /tool="antismash"
                     /translation="LGSDASGVIVRLG"
     gene            complement(10894..12708)
                     /locus_tag="G339_RS0128905"
     CDS             complement(10894..12708)
                     /NRPS_PKS="Domain: Condensation_LCL (5-290). E-value:
                     1.2e-34. Score: 111.5. Matches aSDomain:
                     nrpspksdomains_G339_RS0128905_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     168.6; E-value: 4.3e-51)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.2"
                     /locus_tag="G339_RS0128905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_026341873.1"
                     /sec_met_domain="Condensation (E-value: 6.6e-23, bitscore:
                     71.4, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATRPANAAQLALWAEAQADPSTSSSGYFAVTLRGAVAEPDLRA
                     AAVAVLRRHEPLRSVLRLVGDRLHQVVLAADEALAFATADVPCADGAEDAAVRAWMAAG
                     EGRRSWDLAAEPPIRFHLLRHGADRATVVFAVHHVGFDGRSKFVVAADFTGYLGAIRDG
                     ARVRPEALPQPDVPEAGPDIVAEAVDHWRALLADRAGPLELPADAATGRRGVTTTGTVE
                     LDPADVAALRGLARDRGVSTFTTLVAALTGQLRRYGNEAPILGIAADVSDARTRAVAGL
                     QINVVPMAVEASPDKDPVGEARAALARLARYRRVPFAALVAELGDRAAGRLMTQFGISF
                     PRPPAGLRLEVEGLAARWEFFTPNTSATFAQTLQLRADWPRCRVRLDYRQEETGPAAAD
                     RFLDDFRAAVAALTRPDAAGLGPAAARAVGTGSAASGEPYRRAGRLAGRVEPARDPRDP
                     PVLVPAPGAVITAHGPDGEPLPAAVPGRLRAVLAGGETVDTGDRGYVAGDGRARLLGPA
                     GRRWLLHHGVIDVPLVERVARAHPRVAGARIEVREGRRRAAVLTVRPRGGAPAPTVRAV
                     RAHLHAWLPGHDLPGVIEIAETAEPEED"
     aSDomain        complement(11839..12693)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128905_Condensation_LCL.
                     1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="1.20E-34"
                     /label="G339_RS0128905_Condensation_LCL.1"
                     /locus_tag="G339_RS0128905"
                     /protein_end="290"
                     /protein_start="5"
                     /score="111.5"
                     /tool="antismash"
                     /translation="PANAAQLALWAEAQADPSTSSSGYFAVTLRGAVAEPDLRAAAVAV
                     LRRHEPLRSVLRLVGDRLHQVVLAADEALAFATADVPCADGAEDAAVRAWMAAGEGRRS
                     WDLAAEPPIRFHLLRHGADRATVVFAVHHVGFDGRSKFVVAADFTGYLGAIRDGARVRP
                     EALPQPDVPEAGPDIVAEAVDHWRALLADRAGPLELPADAATGRRGVTTTGTVELDPAD
                     VAALRGLARDRGVSTFTTLVAALTGQLRRYGNEAPILGIAADVSDARTRAVAGLQINVV
                     PMAV"
     CDS_motif       complement(12526..12621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128905_0001"
                     /evalue="5.00E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="G339_RS0128905"
                     /protein_end="61"
                     /protein_start="29"
                     /score="18.9"
                     /tool="antismash"
                     /translation="FAVTLRGAVAEPDLRAAAVAVLRRHEPLRSVL"
     gene            complement(12705..14270)
                     /locus_tag="G339_RS0128910"
     CDS             complement(12705..14270)
                     /NRPS_PKS="Domain: AMP-binding (24-412). E-value: 1e-79.
                     Score: 259.9. Matches aSDomain:
                     nrpspksdomains_G339_RS0128910_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     296.5; E-value: 5.1e-90)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.2"
                     /locus_tag="G339_RS0128910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AMP-binding protein"
                     /protein_id="WP_019634554.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-79, bitscore:
                     258.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAPSASLWGGPSAAPCLVDALLETAAGRPDATALVDGDRAFTY
                     AELYAWAAGVRDLLADRGVAPGDRVAVCAPRGAAAVAAMLGAILRGATYVPLDPEYPVR
                     RLEHMVADCTPRLLLSHGDTPYLGESVPIPGPDVRAEPATRPCDPDLAVYIIYTSGSTG
                     WPKGVTVGHRCLDTMVGWQAGHSPRPDLRTAQFAPLNFDVSFQEVLGTLRGGGTLVIMP
                     ERLRREPVELLSWLGEHRVERLFLPYLALQMLGVAARGDLLAGLRLVEVNTAGEQMVCT
                     PEIRALFAALPGCRLVNHYGQSESAMVTSHILGDDPEDWPALPPIGVPLPGCEVLVDPA
                     DPDDPAVGELLVAGDPVSAGYLNRPELTERRYVEIPESPAGNTRAFRTGDLVEIKDGRV
                     RFLTRLDDEVKLRGIRVDLLEVDAQLLADPAVAAAASTIVTTRSGAPSLRAALVTRGDP
                     AELDVPATLERLRAALPEVSVPRSLTVVPELPRTPSGKIDRDAVAALILKELTSSDRRA
                     GRSR"
     CDS_motif       complement(13008..13070)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128910_0003"
                     /evalue="2.00E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="G339_RS0128910"
                     /protein_end="421"
                     /protein_start="400"
                     /score="20.3"
                     /tool="antismash"
                     /translation="FLTRLDDEVKLRGIRVDLLEV"
     aSDomain        complement(13035..14198)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128910_AMP-binding.1"
                     /evalue="1.00E-79"
                     /label="G339_RS0128910_AMP-binding.1"
                     /locus_tag="G339_RS0128910"
                     /protein_end="412"
                     /protein_start="24"
                     /score="259.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ETAAGRPDATALVDGDRAFTYAELYAWAAGVRDLLADRGVAPGDR
                     VAVCAPRGAAAVAAMLGAILRGATYVPLDPEYPVRRLEHMVADCTPRLLLSHGDTPYLG
                     ESVPIPGPDVRAEPATRPCDPDLAVYIIYTSGSTGWPKGVTVGHRCLDTMVGWQAGHSP
                     RPDLRTAQFAPLNFDVSFQEVLGTLRGGGTLVIMPERLRREPVELLSWLGEHRVERLFL
                     PYLALQMLGVAARGDLLAGLRLVEVNTAGEQMVCTPEIRALFAALPGCRLVNHYGQSES
                     AMVTSHILGDDPEDWPALPPIGVPLPGCEVLVDPADPDDPAVGELLVAGDPVSAGYLNR
                     PELTERRYVEIPESPAGNTRAFRTGDLVEIKDGRVRFLTRLDDEVKLR"
     CDS_motif       complement(13158..13235)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128910_0002"
                     /evalue="7.20E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="G339_RS0128910"
                     /protein_end="371"
                     /protein_start="345"
                     /score="34.3"
                     /tool="antismash"
                     /translation="AVGELLVAGDPVSAGYLNRPELTERR"
     CDS_motif       complement(13755..13811)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128910_0001"
                     /evalue="3.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="G339_RS0128910"
                     /protein_end="172"
                     /protein_start="153"
                     /score="25.6"
                     /tool="antismash"
                     /translation="YIIYTSGSTGWPKGVTVGH"
     misc_feature    complement(14199..14201)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14267..14518)
                     /locus_tag="G339_RS0128915"
     CDS             complement(14267..14518)
                     /NRPS_PKS="Domain: PCP (10-76). E-value: 4.2e-21. Score:
                     66.8. Matches aSDomain:
                     nrpspksdomains_G339_RS0128915_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.2"
                     /locus_tag="G339_RS0128915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_019634555.1"
                     /sec_met_domain="PP-binding (E-value: 5.4e-21, bitscore:
                     65.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTTATTVATVTAIWEATLGVDGIAPDENFLDLGGDSMTATKVI
                     AALHREYALEAPMRLIFDHPTVAELAEAVDELRAGVSR"
     aSDomain        complement(14291..14488)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128915_PCP.1"
                     /evalue="4.20E-21"
                     /label="G339_RS0128915_PCP.1"
                     /locus_tag="G339_RS0128915"
                     /protein_end="76"
                     /protein_start="10"
                     /score="66.8"
                     /tool="antismash"
                     /translation="TVTAIWEATLGVDGIAPDENFLDLGGDSMTATKVIAALHREYALE
                     APMRLIFDHPTVAELAEAVDE"
     gene            complement(14515..15777)
                     /locus_tag="G339_RS0128920"
     CDS             complement(14515..15777)
                     /NRPS_PKS="Domain: Condensation_LCL (8-285). E-value:
                     6e-69. Score: 224.2. Matches aSDomain:
                     nrpspksdomains_G339_RS0128920_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     335.7; E-value: 8.8e-102)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.2"
                     /locus_tag="G339_RS0128920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_019634556.1"
                     /sec_met_domain="Condensation (E-value: 1.4e-50, bitscore:
                     162.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVAGAVGPASHGQHRLWLAEQLAPGAYVIQRAFRLRGAVDEDAV
                     RRAADRLAARHEALRTTYRAARGGIEQVVGEPGAVFDAVDAADVDAVIAAERAARFDLA
                     AGPVLRVRLLRTAADDAVLLLTIHHIAFDGWSMEVFFREFAAAYAAFAAGEEPDLPPAP
                     GFLDHVRREAGRDHAASLEFWRRTLAGAPPVSLPADPAPAGPGGAHAVPVALSDATTAR
                     IDRLSRERRCTAYMTTLVLYAAVLARRAGLDEAVLATAASGRLRAEDQNLVGFLSNTVP
                     LRVACPPDATLVEAVDAAREVCLAASEHGAAPYDQVVAASGVARPPGRAPLAQALFDLR
                     PAPGVPELPGLRVEERPIEPTATRLELELHLVRGGAGVRGHLLASPAVLTADTARTLRD
                     RFTRLAAAWTAEPDSQLKEMP"
     CDS_motif       complement(14761..14880)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128920_0004"
                     /evalue="1.30E-09"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="G339_RS0128920"
                     /protein_end="339"
                     /protein_start="299"
                     /score="30.4"
                     /tool="antismash"
                     /translation="REVCLAASEHGAAPYDQVVAASGVARPPGRAPLAQALFDL"
     aSDomain        complement(14923..15753)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_G339_RS0128920_Condensation_LCL.
                     1"
                     /domain_subtype="Condensation_LCL"
                     /evalue="6.00E-69"
                     /label="G339_RS0128920_Condensation_LCL.1"
                     /locus_tag="G339_RS0128920"
                     /protein_end="285"
                     /protein_start="8"
                     /score="224.2"
                     /tool="antismash"
                     /translation="PASHGQHRLWLAEQLAPGAYVIQRAFRLRGAVDEDAVRRAADRLA
                     ARHEALRTTYRAARGGIEQVVGEPGAVFDAVDAADVDAVIAAERAARFDLAAGPVLRVR
                     LLRTAADDAVLLLTIHHIAFDGWSMEVFFREFAAAYAAFAAGEEPDLPPAPGFLDHVRR
                     EAGRDHAASLEFWRRTLAGAPPVSLPADPAPAGPGGAHAVPVALSDATTARIDRLSRER
                     RCTAYMTTLVLYAAVLARRAGLDEAVLATAASGRLRAEDQNLVGFLSNTVPLRVA"
     CDS_motif       complement(14929..15012)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128920_0003"
                     /evalue="3.50E-09"
                     /label="C5_LCL_267-296"
                     /locus_tag="G339_RS0128920"
                     /protein_end="283"
                     /protein_start="255"
                     /score="29.1"
                     /tool="antismash"
                     /translation="VLATAASGRLRAEDQNLVGFLSNTVPLR"
     CDS_motif       complement(15334..15399)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128920_0002"
                     /evalue="2.20E-13"
                     /label="C3_LCL_132-143"
                     /locus_tag="G339_RS0128920"
                     /protein_end="148"
                     /protein_start="126"
                     /score="42.5"
                     /tool="antismash"
                     /translation="IHHIAFDGWSMEVFFREFAAAY"
     CDS_motif       complement(15586..15699)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_G339_RS0128920_0001"
                     /evalue="1.10E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="G339_RS0128920"
                     /protein_end="64"
                     /protein_start="26"
                     /score="50.0"
                     /tool="antismash"
                     /translation="AYVIQRAFRLRGAVDEDAVRRAADRLAARHEALRTTYR"
     gene            complement(15777..17417)
                     /locus_tag="G339_RS35695"
     CDS             complement(15777..17417)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 182.8; E-value:
                     1.7e-55)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.2"
                     /locus_tag="G339_RS35695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA/acyl-ACP dehydrogenase"
                     /protein_id="WP_019634557.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.5e-16, bitscore:
                     50.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.1e-21, bitscore:
                     66.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARGSLSVPGVPNVVEEICHGRLPWDLVHPFPAQAGADRAAGDAA
                     VAGVRAALAGLPDEPDGETVAEALRAGGWLHLLAPAEVGGRELSPYNAFRVITEASGEA
                     LPAGFMLAIHNGIGAAAYLPVLPDGPIRELVMKRLAAGAVTGMADTEPAGAANRRRFTT
                     ATADADGYVLDGDKLYIGNGPIAELLAVTATEDGRPRVFFVDTASPGFEVRARLEFMGL
                     RGFPNGALALRGVRVPRELVLAEQGGQWLSAERAAVLSRGRVHIIAAPALALARRALEH
                     TGEYVRRRSVDGRALGTYDEIQRAVAESAADLYALDATARWTMLGDQGPDPVNLMPEQF
                     AAKDITSLLCWRIVERAMTVMAGEGYETARGKAARGAPPAPLERLYRDARGLRIAGGTE
                     VLLQGRLADRIALACLEPDEIDARAHVPDVPELTARNREHLARLAGQIGTFSQHCADVL
                     RNHPDPAERAGLGRPLTLLGAILEELVTVTLTLARAAGDAPDAQDLADVYCTGAWRSLD
                     AHWSGLVDALAGAGPDHARISAAWLGPVT"
     gene            complement(17404..18048)
                     /locus_tag="G339_RS35700"
     CDS             complement(17404..18048)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016207.2"
                     /locus_tag="G339_RS35700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FMN-binding negative transcriptional regulator"
                     /protein_id="WP_240489931.1"
                     /transl_table=11
                     /translation="MRSNPLAMLVTRGERALPWITHLPVITHPERPPAELPGATLLGHM
                     NAANPHWAAVASGGPGTLVFTGPHGYVSPTVYELPVAAPTWDFVAVHVHGTLRPLDTPE
                     DARRVVRWTVEAYEGTHGTGWDPEGSLDYFDKILPGVRAFEFHVESVDGMYKLSQEQEP
                     ETRRRVVRSFAASGRGAHAELSALIDRFGDPGPGAPATGCPAAREAGDGAR"
     CDS             complement(18119..>18535)
                     /codon_start=3
                     /gene="mce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911239.1"
                     /locus_tag="G339_RS0128935"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="methylmalonyl-CoA epimerase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VHARRPRRHRLPRPGGDDPVLPGLLRLRGVPPRDQRGAGRPRGDA
                     ARQRHRRRPRHLPAAPVADAAGLAGGPVPGRARRGRPPRRVRLPGRGPRRRRAARRGPA
                     GPVRSAAARLDGLAGDLPAPEGLPRRPGGARDIL"
     gene            complement(18119..>18535)
                     /gene="mce"
                     /locus_tag="G339_RS0128935"
                     /pseudo=""
     gene            complement(18535..19833)
                     /locus_tag="G339_RS0128940"
     CDS             complement(18535..19833)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 525.7;
                     E-value: 1.3e-159)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852990.1"
                     /locus_tag="G339_RS0128940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lysine N(6)-hydroxylase/L-ornithine
                     N(5)-oxygenase family protein"
                     /protein_id="WP_019634560.1"
                     /transl_table=11
                     /translation="MTGPATDADDILDIVGVGFGPSNLALAVAVREHNADRPAAEHLTQ
                     VYFEKQPAFGWHRGMLIDGATMQVSFIKDLVTMRNPASEYGFLSYLHDNDRLADFINHK
                     SLFPSRVEFHDYLEWVARRFQDVARYGSEVVAMRPGPGGDHIEVIVRRGGEHRVQRARN
                     VVVAVGQEPALPDDIELGDRIWHCAQLLERVERLTEEPRRAVVVGAGQSAAETTEFLHR
                     RFENAEVSAIFLRYGYSVADDTPFANRIFDPESVDVFYGAPENVKRMLFDYHRNTNYSV
                     VDQELADELYRRVYQERVRGVERLRILNASRLHAVRRDVTGDGLRVDVEHLPTGEKRSF
                     GVDLVVYATGYRPIDPANVLGEVAEYCRRDAGKRPAITRDYRLETDDRLRAGIYLQGGT
                     EQTHGISAQLLSNTAVRAGEIVRSIAGARVGAV"
     gene            complement(19830..21686)
                     /gene="asnB"
                     /locus_tag="G339_RS0128945"
     CDS             complement(19830..21686)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 608.7; E-value: 1.9e-184)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596043.1"
                     /locus_tag="G339_RS0128945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_019634561.1"
                     /sec_met_domain="Asn_synthase (E-value: 9.6e-90, bitscore:
                     291.9, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.8e-44, bitscore:
                     140.9, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGITGLVDFRRRADTDDTGLIEAMTDTLHRRGPDERGVWRHGHA
                     ALGVRRLSVIDLAGGKQPMVDERPDREPVAIAYTGEVFNCPELRAELGARGHRFETTSD
                     TEVVLRAYLEWGAGCAERLLGMFAFAVWDARTEELLLIRDRLGIYPLYYAEIDGGVVFG
                     SEPKGILAHPQIRPEIDQSGLRAIVTLVKSSDHGIFKGMFEVDPGSIVRFGRGGLAKSR
                     FWSLQAVEHTDDLDTTVRTVRDLLEDSVRRQMVSDVPLGVFLSGGLDSSALAALAIRTG
                     GSDEKLRTFSVNFTGHADAFKPDEVRATPDFPFVKIMSEFLGTRHTAVELSADQLMDAE
                     ARSTVLTARDHPTSLGDLDTSLYLLCKAFREQCTVSLTGDGADELFGGYHWFHEERFRG
                     EGTMPWLEFARRMAGKNQMRSSGLLAPDLADVLEADEYERAEYEKAVAGVPVLEGESDI
                     DRELRRITYLNMTGYLRIILDRRDRMGMAAALEGRVPFCDHRLVEYVFNVPWEMKTFDG
                     REKSLLRAAVRDLLPPSVLYRKKAGYPPTDDPRYGALLNARLAEVVADPKAPVRDLLDL
                     GTAKSFVEDPTGPAAEVVNRFSIEMVLGLNEWLGRYDVGLAL"
     gene            complement(21725..23170)
                     /locus_tag="G339_RS35705"
     CDS             complement(21725..23170)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013781.2"
                     /locus_tag="G339_RS35705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="WP_019634562.1"
                     /transl_table=11
                     /translation="MAGPGEFPYEAGIHPTGYTTRPWTVRQLAGLGDGEDTNRRFHYLL
                     ERGETGLSLAFDLPTQMGIDPDEPAAEGEVGRAGVSVATVDDFASVFTGIPLDQVSVAY
                     TINATAPMILAMWIVAAEESGVDPAALRGTLQNEMLKEHLARNAVIFDLDDSFRFSLDV
                     IEYCVRHLPKVNPISISGGHAREAGANRALEVALGIADAEQYLDHMIARGYGVDEVAPR
                     LSFIFGTHMELLAEAAKFRALRRMYARRMAERYDARNPRSMRMRIQVNTFGSTLAATEP
                     LNNIARTTVQAVAAVLGGVQSLHVCGFDEAAQIPGRLAARVALRVQQILLTETDLARHV
                     DPLGGSGVIAGLVDEIEADADRWLTEIDKRDGLLACLRSGWLEGEIEEMAYASPGPRVG
                     VADAEDAAEERRLMREQLRTGVAAGRRRPFARVDRPAELAALTDDVALGRNAMPAMIRA
                     VRARASVGQLHRALSAGLARGRA"
     misc_feature    complement(22751..22753)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(23172..23990)
                     /locus_tag="G339_RS0128955"
     CDS             complement(23172..23990)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023015.2"
                     /locus_tag="G339_RS0128955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diiron oxygenase"
                     /protein_id="WP_169514798.1"
                     /transl_table=11
                     /translation="MPYLDHPVVAELPDELHLSLGVWHLYAYLDSVANLESKVVNRATL
                     LVADDGLGLGLPAEVRLDAWKIYCDEAHHAMSNFDLVCQVERKTGVPHLPYTFAPVTGA
                     LTRATEPLRADAPGLGRLLEAVIFETVVTSLLETIPRSAEVVPTVRDVVADHARDERLH
                     HAFYTIFFDRLWGGLEPAVRERVARVLPALVRACLATDTVAHTTSLRAAGLTAEQAEQV
                     LAETYTPRFETDQIRQAARRTLRMFAEHDVFDHPGARESFEASGLLIGEI"
     misc_feature    complement(23937..23939)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(23955..23957)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcagaacgcg tcgggcagcc agcgctcgta caagacgacc tcgtcgaccg ccacctggat
       61 cgcgctcggc gcgggctccc cgtccgcccc gagtccggcg aggtagggcg cgcgggcgac
      121 gatgcgggcc cggccgccca cccgcagcgc gtcccggcgg ccggggacca ggaacagcag
      181 cccgacccgc ggattggcca ggacgtcgcg gtgcgcgtcc aggcggccgc ccggcccgtc
      241 cggcaggacg agggtgcggt cgtccaggac gcgggccgcg ccgcgcggcg acaccgcgca
      301 ccgcccggcc gcgtcggcgg tggccagcag gcagagcgcc gcggcggcga gccagtcgcg
      361 ggcgcgggcg tcgagaccgg agtgcccgtt gtgcgcggcc ggggcggcgg cgtcgccgta
      421 cagggcgagc agcgcggcct cgtcctcgac gtactcgacg tcggcgacgg cggtcgggcc
      481 gtcgcgccgg atgccgcgcg cgaccagctc gtcgacgagg gccgccgtcc cctcgtcctc
      541 ggtcgcgacg gtggtgatga cgggcggccg cgcggacgcg gtgttcagcg ccgtcatggc
      601 gttgaggtcc cggacgatcc gcgccgcgcc cggccggtcg gccttgttga cgacgtagac
      661 gtccccgatc tccagcacgc ccgccttggc gatctgcacg gcgtcgccgg tcccgggcgc
      721 gagcacgacg gccgtggtgt cggcgagcgc ggcgatctcg acctccgact gcccgacgcc
      781 gacggtctcc accagcacga cgtcgaaccc ggccgcctcc atgacccgca ccgccgcggg
      841 cgtcccggcc gacagcccgc cgaggtgccc gcggctggcc atcgaccgga cgaagacgcc
      901 gccgtccccg acgtgccgct gcatccggat gcggtcgccg agcagcgcgc cgccggtcag
      961 cggcgaggac gggtccacgc acagcaccgc gacgcgccgg tcccggcgcc ggaactccgc
     1021 gatcagcgcc gaggtgagcg tggacttgcc gacgccgggc ggccccgtca gccccaccac
     1081 cagcgcccgg tcccggcggc gcagcgcctc ggcgacggcg gggtgcccgc cgggcccggc
     1141 cgcgtccagc agggtgagca ggcgggagac cgcgcgccgg tcccccgccc gcgcccggtc
     1201 cagcaggctc actcggccac ctcgaggggc cgcagctccg cccgggccca ggcgatgatc
     1261 tcctcgacgg agctgctggg cgtgaagatc cggacgatgc cgagcccggt gagggcgtcg
     1321 atgtcgtcgg gcgggatgat gccgccgcag aagacggcga cgtccgccgc gtcggcggcg
     1381 gcgagcaggt ccaggacgcg cgggacgagc gtcatgtgcg cgcccgacag cagggacagc
     1441 ccgatcgcgt ccgcgccctc ctggatcgcg gtctccacga tctgctcggg cgtctggtgc
     1501 aggccggtgt agatcacctc cagcccggcg tcgcgcagcg cgcgggcgac gaccttcgcg
     1561 ccgcggtcgt ggccgtccag gccgggtttg gcgatgacga ctcggacgcg tctcaccggt
     1621 ccgcctcctt ggttccgggc gcgagggcgc gcacgaggtc gagcagccgc gtccggccgg
     1681 gttcgtcgcg caggtagaag tggccgccgg gcagcatgtg caggtcggcg ccgcgcgcgg
     1741 tgtgccggtc ccaggcgcgc agcaggtcgg cgggcatcgc gtcgtccgct ccgccgacga
     1801 cggtgatcgg cacgtcgatc gggtcgccgg gcgcgtgctc gtactcctcg aagatctgga
     1861 agtcggcgcg gtaggcgggc aggacgagcg cgagcaggtc ggggtcctcg cgcagcgtcg
     1921 ggggcaggcc gccgtagcgc tgctcgacgg cgtccagcag gtcgtcgtcg cccatccggt
     1981 gcagcgggtc gcgttcgacg cggaagtgcg gcggcggcgt cgcggacacg acgagccgtt
     2041 cggggagcgg gcggccgctc gcctggagcg cgcggatcgt ctcgaacgcc acccagccgc
     2101 cgaggctgtg cccgaacagg acgtacgggc cggtgaactc gacgtcctcc acgacggcgg
     2161 cgacgagggc ggccatgtcg gtgaacggcg gttcctccag gcgcgcgccc cggccgggga
     2221 gttgcaggcc gaggacctcg acgtcggtga gcgcgtccga ccagcggacg aactcgccgg
     2281 gcgagccgcc gctgtgcggg aagcagtaca gccgcagcgc cgcgtcgccg cgccgtcggc
     2341 ggcgcacgag ccagcgcgac gcgccgggcg agcggccccg gcggacgctg cggggccgca
     2401 tgtcggtcca cacgcgggcg acgtggtcga ggcagtcccg ccgcgacccc tggaacccgg
     2461 tcggcgtcca gccgggcgcg gcggcgcgcc cggccggcca caggccgtac tcggcctcgt
     2521 cgttggtcac cacgtcgtac acggtcatcg ggtctcctcc tgggcgcggc cggtgacgag
     2581 gtcggcgagg cgggcggggg tcggcgcgcc gtagatctcg cgggcggtga cctcgacgcc
     2641 gcggtcggcg cggatccagg cggcgagccg ggtcgcgatc agcgagtccc cgccgagttc
     2701 gaagaagtcg tcgtggcggt cgacggtgtc gaggccgagg atgacggcga agccctcggc
     2761 catgcgggcg gcgtcggtgc tccgcggctc cggcgcggac gcgggcgcgg gcggcggggc
     2821 gggctcgtcg gcgtcggacg tctccagcga gaagcgcctg cgctggaacg ggtagagcgg
     2881 cagcttgacc cggcggcgcc gctcgccctc gtggacgcgc gcccagtcga cgggaatccc
     2941 ctcggcccac agccgtccga gggccgtgag cgcggtgtcg agcgcggacg cgtcgtcggc
     3001 cgggtgcggg aggctctgcg cgatgacgcg cgacgcgggc cgctcgggat gctgccgggc
     3061 gagcgtggcc agggtgcggc cggggccgac ctccagcagg acggcgtcgg gctcggcgaa
     3121 cagccgggac agcgcggcgg agaaccgcac ggggtcgcgc atgtggcccg accagtacgc
     3181 ggggtcggtc agctcggcgg gcgcggccca gtcccccgtc cggtcggaca ggaaccggac
     3241 ggcgggttcg cgcagcggga cggcgcggac ggcggcctcg aactcgtccc tgatccggtc
     3301 gaccagcggc gagtgcccgg cggtggcgat gcgcagcggc ttggagtcga cgccccgggc
     3361 cgtcagctcc tcgtggaagc gcgcgacgtc ggcggcggcg ccggtgacgg tcgtccggcc
     3421 ggggccgttg acggcggcga cggacagggc gggcggcagc agcggcgcga cctcgtcctc
     3481 cgagagctgc accgcgagca tcgtcccggt gggcagcgac tccagcagcc gcccccgctc
     3541 cacgaccagc ggcaccgcgt cgtccaggtc gatgatcccc gcgacgcacg cggcggcgta
     3601 cgcgccgagg ctgtgcccgg tgacggcggc gggcgtgatg ccccacgccg tccacagccg
     3661 ggcgagtgcg tactcgacgg cgaacacggc gggctggccg accgagatcc gctccagcgt
     3721 ccgttccgcg tcggcggcgc gctccggcgg cgggaacagg atctcccgca ggtcgagccc
     3781 gaggcccggc agggccaggt cggcgcagcg gtcgaaccgg cggcggaact ccggctcctg
     3841 ctcgtacagc tcgcgggcca tgccgacgtg ctggccgccc tgcccgggga acatgaacac
     3901 caccggccac tcgcccgtcc ggccggacgg ggccgggcgc ggcgcggtga gcgcgcgggc
     3961 cgcggccgcc gcgtcgcccg cgaccgcgaa cgcccggtag gggtgcgcgg gccgcccgtc
     4021 ctggagcgtc caggcgatgt cggcgagcga ccccgagggc cgcgccgaca ccgccgccgc
     4081 cagcgacgac gacagctccg ccagcgcctc gggactgcgg gcgctcacca ccaggagctg
     4141 gctgccgcgc ccggtgtcgg cgggcggctg gacgggcggc tgctccagga tcgcgtgcgc
     4201 gttggtcccg ccgatgccga gggcgttgac gcccgcgcgg cgcggcgtcc cgccggtctc
     4261 ccacttggtg aggtcggtgg tgacgcggaa ccggccggtg tccaggtcga gttcggggtt
     4321 gggccggtcg aagtgcagcg tcggcggcag caggccgtgc tcgacggcca gcgccgcctt
     4381 gatgaacgcg ctgaccccgg cggccgcgtc ggtgtgcccg atgttggtct tgaccgagcc
     4441 gagggcgcgg ccgcccgcgt cggcggcgac gggcccgagc gccttcgtca gcgcccgcac
     4501 ctcgatgagg tccccgagcg gggtgccggt cccgtgcgcc tccacgaacg tgacggtgcc
     4561 ggggtcgacg cccgcgcggt ccagcgcggc gcggatcacc cggacctggc cgtccacgcc
     4621 cggcgcggtg aacccgacct tgccgccgcc gtcgttgccg atcgcggtcg ccagcaggac
     4681 ggcgtggacg tggtcgccgt ccgccagcgc gtcctccagc gggcgcagcg cgaccagcgc
     4741 ggcggcgctg ccgcccacgg cgccgcgcgc gtcggcgtcg aaggcgcgca gccgcccgtc
     4801 cgcggagatg atgccgcccg gcgtgtagcc gccgcgcggc ggcgggacgt ggacggtcgc
     4861 gccgcccgcc agggccatgt cgcactcgcc gtccaggacg gcgcgcgcgg cgaggtggac
     4921 ggcgaccagg gaggtcgagc aggccgtctg caccgacacg acgggcccgc gcaggccgag
     4981 ccggtcggcg gcgcgggcgg ccaggaagtc ggggccggtg ccgagccgca tctgccaggc
     5041 gtccacgaag gggaggcggt cgcggtgggc gcggagccgg gccaggtgct cggtggtcgc
     5101 tcccccggcg aacaggccga tggtgccggg gaagcgggcg gggtcgtggc ccgcgtcttc
     5161 cagggcgtgg taggcgcatt cgaggaagac ccggtgctgc gggtccatga tcagggcctc
     5221 gctgggcggg cagccgaaga aggcggcgtc gaagcggtcg gcgtcgtcca ggacgccgtg
     5281 gacgtccagg tgcccgtcgc cctcggcgag gacgcggatc gagtccacgc cgccgcacag
     5341 gttcgcccag aactccgcga cgctcggcgc gcccgggaac cgcccggcca tgcccacgac
     5401 ggccagcgcc cgcgagtcgc cgcgcggccg cgacgccggg acgggcgcgg gcgcgggggc
     5461 gtcgcggggt tcgagccggt cggacaggct ccggatcgtc ggcgcctcga acagcgcgac
     5521 gagcggcagg tcgtgcccca ggtcctcggt gagcgtccgg tggacctcga ccagcagcag
     5581 cgagtggccg ccgaggtcga agaacgagtc gtcgatgccg acgcgctcca ggtgcagcag
     5641 ctcggcccac agcgcgcaga gccgccgttc gaggccggtg cggggcgggg tgtgcgcggc
     5701 cgacgcggcg gggcggcgcg cgtcgggctc ggggagccgg gcgcggtcca ccttgccgtt
     5761 ggcgttgagc ggcagcgcgt ccagcgcgac gaagtaggcg gggatgagcg cgcgcggcag
     5821 ccgctccgcc aggtacgcgc ggagttcgcc gacgtcgtcc gggcctccca cgacgtaggc
     5881 gaccaggtgg gtctcgtcgt cgccgggacg ggtgtagggc gcgacgtgcg cgacggtcac
     5941 ggccgggtgc gccgtgagga cgacggcgat ctcgccgggc tccacccggt tcccgcggat
     6001 cttgacctgg tcgtccacgc ggcccaggaa ctcgatctcg ccgtccgggc gccgccgccc
     6061 gaggtcgccg ctgcggtaca tgcgcgcgcc ggggcggccg gagaacgggt cgggcgggaa
     6121 ccggtcgacg gtctgcgcgg ggtcggcgag gtagccgcgc gcgacgcccg tcccgccgat
     6181 gtagatctcc ccgggctccc cgtcggggac gggtcgcaag tcctcgtcca ggatgtggac
     6241 ggcggcgatc gacagcggcg cgccgatcga cggcggcccg tcgcccgccg ccgcgaccgg
     6301 ccccgacgtc gcgatgatcg tcgtctcggt cgggccgtag ttgttgacga cctggaacgg
     6361 gagcccggcg ggcggccgga acttcaggcg ctcgccgccc gtcagcagcg tccgcagcgc
     6421 ggtgtccgcc ggccacggca gggtgagcag ccgttcggcg agggcggtgg tgaggaacag
     6481 gacggtgatc cgctcggcca ccagccagtc ccgcagcgcg cgcgggtcga gcagggtgtc
     6541 ctcgtcggcg gcgtgcaggc aggcccccgc ggcgagggtc ggccagatgt cccaggcgga
     6601 cgcgtcgaag ccgggcgagg cgatcagcgc gacgcggtcg gcggggccga ggccgaacgc
     6661 gtcggcgtcc cagcgcgcga agcgggccag ggagccgtgt tcgagcagga cgcccttggg
     6721 ggcgccggtg gagccggagg tgaagacgat catcgcgacg tcgcggtcgc gggtccggtc
     6781 gggcggggcg gcgaccggat cggcgggcac ctcgtcgagt aggacgggcc gcagtccgcg
     6841 cgcggccagg ccgtccgcta actccgcggt cgtgacgacc agcgcggcgc ccgcgcgggt
     6901 catggcctgg gccgtgcgct cgacggggtg gcgggggtcc gccggggcgt aggccgcgcc
     6961 cgtcttcagg atcgcggcct cggcgacgac caggtccgcg ccgcgcggca gcaggacgcc
     7021 caccacgccg ccgggcgcgg cgccgcgccc ggcgaggagg gcggcggccc ggtcggagcg
     7081 cgcgtcgagt tcgccgtagg tgagcgtccg ggcgccgtgc cgcacggcgg gcgagtcggg
     7141 actcgccgcc gcgcgggccg ccaggagccg gtgaaccgcc gtccatgcca tgctgtcgcc
     7201 ttccgatcgt ggtgtggggg tcgccgcccc ggcgggtcag ccgtcgcggt tcggcgtgtc
     7261 ggcgcccgtg tcggcgcccg tgtccgcgcc cgcgtcgacc gcgaccttgg gcggctcggg
     7321 ggcctcggcg tccggcccgt ccgcggcgga ccgccgcggc aggagcgcga acgcgatgac
     7381 gccggtcgcc gcgctgacgg cgaacgcggt gaagaacgcc aggtgcaggc cgtgcgcgaa
     7441 cgcgccggcg acgaggtcgt gcagccggtc ggccgcgacg ccgggcacgc gcagcgggcg
     7501 gctggcggtg gcgtcgtcga cggcccggtc gagcgcgtgc ccggtgacgg actcgccgcg
     7561 gagccggtcg cgcaggtcgc cggtgaaccc ggtggcctgc acggtgccga gcaccgcgat
     7621 gccgagcacg gtccccagct gcatggaggt ctcgaccgtg ccggacgccg cgcccgcgcg
     7681 ctcgggcggc agcgacgtca gcgcctgggt ggtgttggcg ggcagcgcca ggccgaggcc
     7741 gacgccgacg agcgcgaccg cccaccagga cgcccagtag ccggagtccg cgccgagcgt
     7801 cgacagcccg aacagcccga ccgcgccgag cagcaggccg ccggtgatca gggaccgcgc
     7861 gccgacctgc ttgacgagct tgccggccag cggcgcgcag aacatcaggc cgagcgcgcc
     7921 gggcaggaac ccgaacccgg cgtcgagcgc gtcgtggccg aggacctgct ggatgtagag
     7981 ggacaggaag tagtacgccg ccgacagcgc gaagccgagg acggcggcga cgaggttgct
     8041 ggccgcgaag acccgggagg tgaacgaccg caccggcatc atcgggtgct cggcgcggac
     8101 ctccacgacg acgaacaccg cgagggcgag cgcgccgacg acgaacccgg ccagcacgcc
     8161 gggcgcggac caaccctgcg cgtggccctc gatgaggctg taggcgagcg cggtgggcca
     8221 cagcacgccg aggacgaggc cggggacgtc gagggagccg ccctcgccgg gcacgacctt
     8281 cggcgcggcc gccaggatga gcacgagcag cagcacgccc gcggcgatgt tgaacccgaa
     8341 gatcagccgc cacccggaca ggtggacgaa ccagccgccg agcagcggcc cgagcgcgat
     8401 ggcgacgccg ctgagcccgc cccacgcccc gaggagcttg gccttgcgct cgggttcggg
     8461 cgcgagccgg ctgatcatcg ccatgctggc cgggacgagc atcgcggccg ccgcgccctg
     8521 gacggaccgg ccgacgatga ggagccacac cccgtcggcg gcgacgcaca ccaccgagcc
     8581 gagggtgaac agggcggtgc tggcgatcag cccggtgcgg tggccgagcc ggtcgctgat
     8641 ggtgccgccg accatgagca gcccggcgaa ggccagcgtg tagcagtcga agatccactg
     8701 cagcccggac agggacgcgt gcaggtcgtc gcggatggcg ggcatcgcca cggcgctgat
     8761 cgacaggtcg accatcgcca ggaaggccgc gccgaacacg gcgacgatcg cgcctgctcc
     8821 gtggcgtggg gggctgttgt cgggcactgc gtgctcctcg gggggatcgg accaccctgt
     8881 ccggcgggcc cggtcagggg ggtggggccg gttcggtgcc gggctccagc agcgggaaca
     8941 gccgggagac cacggcgacg ggagcggcgt cggccggacg ggcgtcgggc cgggactcgc
     9001 ggtgccggta ctgggcgacc agcgcccgga tcacccgcgc catcccggcc atctcctccg
     9061 gggtcaggta cgcgacctgg ctgaacgcct cgtcctgccg ccagcgggcg ggcgcggcgt
     9121 cgcggtgttc gagccagcgc cggaagctct cgtcctccag gccgcgcgcg aacaggtcca
     9181 ggcatgcgtc gctgaccggg ccgggctcgg gcggcggggc cgccccggcg tccggtccgc
     9241 ccgcgtccgg ggacggcggg gtcgccagcc gccagggccg cacccggccg cgcccggccg
     9301 gggcctcctc gatgagcccg ccctgggcga gcctgcggag gtggaaggag tacaggccgc
     9361 tgctgccgcc cagctcgcgg gcggccgtgg tggccgtgac gacgccgtcg cggcggagca
     9421 ggcgcagcag gtccctgcgc accgggtgcc ccgccagttc ctcgttgtcg ccgtccggcc
     9481 gcgcgtcgct cactttgcaa accatagtgc ttgcaaagca ggggatcaaa gcggccgccg
     9541 ggcggtcagc ggcccgcacc gagcggccct cccaccatga gcggagcggt cccgcgcgcc
     9601 ccgacgcgct cgcgcagcgc ggcgtcggcg acgcccagcc cggcgcgcgg cgcgaggcac
     9661 aggacgccga ccttgccgat gtgctcgttg agctgcacgc cgcgcgcggc ctcgggcgcc
     9721 tcggccagcg ggtacaccgc cgacagcatc gaggcgacct tcccgcgccg cacgagccgg
     9781 ttggtctccc actgctcctg gaggttcgcg ccgtggctgc cgatgatccg cttcagccgc
     9841 atccacaggt agcggttgtc gaaccggtgg tcgtagccgg tgctcgaccc gcacgtcacg
     9901 accgtcccgc cgcgcgcggc gacgaacacc gagatcccga aggtggcctg gccgacgtgc
     9961 tcgaacacga tgttggggtc ctcgccgcac tcccggcgga tgatctttcc gagtttcttg
    10021 cccgccgact ggaccacgtc cgggtccgat ccgatccggc ccagctcgcg gcggtcgatg
    10081 accagctcgc agcccaggtc gcgggcgatc tcggccttgc ggtcggagct gacgatcccg
    10141 atcggcgtcg cgccgccgtt gcgcgcgaac tgcacggcgt agccgccgag gccgcccgcc
    10201 gcgccccaga tcagcaccag gtcgccctgc ttcatgttcg cgccgcggtc gctgacgagc
    10261 atccggtagg cggtcgccgc gcacagcggg ttgcaggcgg cctcctccca ggtcaggtgc
    10321 tcgggcttgg ccaggagctg gctggcgcgc acgaccgcgt agtgggccag gccgccgaag
    10381 ttggtctcga agccccaggc gcgctggtcg ccgccgagca tcccgtcggc gtgggtggcg
    10441 gggtcctggt cgtcgacgta gttggtcgcc acgacgaccc ggtccccgac cttccagttc
    10501 cgcacgcccg accccaggcg cacgatgacg cccgacgcgt ccgacccgag cacgtggtgc
    10561 ggctggtcgt ggcgggtcgc ccagccgccc tgccgcccga aggacttcag gaacgcgaac
    10621 gtcggcagcg gctcgaagat cgccgaccag acggtgttgt agttcatggc cgacgccatg
    10681 acggcgacca gcgcctcgtc gggcgccagc tcgggcatcg gcacctcgcc gacgcgcagg
    10741 gacttgcgga cgtccttgtc ctcgacgccg cggaacatcc ccgcgtcctg cacgcgcgtg
    10801 tgcgcggcgg tgtaggcgtc cggaaccggg atgcgctcca ggacgtcggc gggctccccg
    10861 gcgacgacgg cctcggcgag agcgtccatg cgatcagtcc tcctcgggtt cggcggtctc
    10921 ggcgatctcg atgacgccgg gcaggtcgtg ccccggcagc cacgcgtgca ggtgggctcg
    10981 cacggcccgg acggtcgggg cgggcgcccc gccgcgcggc cggacggtca gcacggccgc
    11041 gcggcggcgg ccctcgcgga cctcgatccg cgccccggcc acgcgcgggt gggcgcgcgc
    11101 cacccgctcc accagcggga cgtcgatgac gccgtggtgg agcagccagc gccgcccggc
    11161 ggggccgagc agccgcgcgc gcccgtcgcc ggcgacgtag ccgcggtcgc cggtgtcgac
    11221 ggtctcgccc ccggccagga cggcgcgcag gcggcccggc acggcggccg ggagcggttc
    11281 cccgtccggg ccgtgcgcgg tgatgaccgc gccgggggcc gggacgagga cgggcgggtc
    11341 gcgggggtcg cgagcgggtt cgacgcggcc cgcgaggcgg cccgcccgcc ggtacggctc
    11401 gccgctcgcg gcggaacccg tgccgacggc gcgcgccgcg gccgggccga gtccggcggc
    11461 gtccggccgc gtcagcgccg cgacggccgc gcggaagtcg tccaggaacc ggtcggcggc
    11521 ggccggtccc gtctcctcct gccggtagtc cagccggacg cggcagcgcg gccagtccgc
    11581 gcggagctgg agcgtctggg cgaacgtggc cgaggtgttg ggcgtgaaga actcccagcg
    11641 ggcggccagc ccctcgacct ccagccgcag tccggccggg ggccggggga aggagatccc
    11701 gaactgggtc atcagccgcc cggcggcgcg gtcgccgagt tccgcgacga gcgcggcgaa
    11761 cggcacccgc cggtaccggg cgagccgggc cagcgcggcg cgcgcctccc cgaccgggtc
    11821 cttgtcgggc gacgcctcga cggccatcgg cacgacgttg atctggagcc cggccacggc
    11881 gcgggtccgg gcgtcgctga cgtcggcggc gatgccgagg atcggggcct cgttgccgta
    11941 ccgccgcagt tgcccggtga gcgcggcgac cagcgtggtg aaggtgctga cgccccggtc
    12001 gcgggcgagg ccgcgcagcg cggcgacgtc ggcggggtcg agttcgaccg ttccggtggt
    12061 ggtgacgccg cgccgtcccg tggccgcgtc ggcggggagt tcgagggggc cggcgcggtc
    12121 ggccaggagc gcgcgccagt gatcgacggc ctcggcgacg atgtcgggac cggcctcggg
    12181 gacgtccggc tgcggcagcg cctcgggccg cactcgcgcg ccgtcccgga tcgcgccgag
    12241 gtagccggtg aagtcggccg cgacgacgaa cttgctgcgc ccgtcgaacc cgacgtggtg
    12301 gacggcgaac acgaccgtgg cgcggtctgc gccgtgccgc agcaggtgga accggatcgg
    12361 cggctcggcc gccaggtccc aggaccgccg cccctccccg gcggccatcc aggcgcggac
    12421 ggccgcgtcc tccgcgccgt ccgcgcacgg cacgtccgcc gtcgcgaacg ccagcgcctc
    12481 gtccgccgcc aggacgacct ggtgcaggcg gtccccgacc agccgcagca ccgaccgcag
    12541 cggctcgtgc cggcgcagga cggcgaccgc cgccgcgcgc aggtccggtt cggcgaccgc
    12601 gccgcgcagc gtgacggcga agtagccgct gctgctggtc gacgggtcgg cctgcgcctc
    12661 ggcccacagg gcgagctgcg cggcgttcgc cgggcgcgtc gcggtcaccg ggaccgcccg
    12721 gcgcggcggt cggaggaggt cagttccttg aggatcagcg cggcgaccgc gtcccggtcg
    12781 atcttcccgc tgggcgtgcg cggcagctcg ggcacgaccg tcagggagcg cggcaccgac
    12841 acctcgggca gggccgcgcg cagccgctcc agcgtcgcgg ggacgtccag ctcggcgggg
    12901 tcgccgcgcg tgacgagcgc cgcgcgcagg ctcggcgcgc ccgagcgggt ggtgacgatc
    12961 gtgctggcgg ccgccgcgac ggcggggtcg gcgagcagtt gcgcgtccac ctccagcagg
    13021 tcgacgcgga tgccgcgcag cttgacctcg tcgtccaggc gggtgaggaa ccggacccgc
    13081 ccgtccttga tctccaccag gtcgccggtg cggaacgcgc gggtgttgcc cgccggggac
    13141 tccgggatct cgacgtagcg gcgctcggtc agctcgggcc ggttgaggta tccggccgag
    13201 accgggtcgc ccgccaccag cagttcgccg actgccgggt cgtcggggtc ggcggggtcg
    13261 accagcacct cgcagccggg cagcgggacg ccgatcggcg gcagcgcggg ccagtcctcc
    13321 gggtcgtcgc cgaggatgtg ggacgtgacc atcgccgact cgctctgccc gtagtggttc
    13381 accaggcggc agcccggcag cgcggcgaac agcgcccgga tctccggcgt gcagaccatc
    13441 tgctcgcccg cggtgttgac ctcgacgagg cgcagcccgg ccagcaggtc gccgcgggcc
    13501 gcgacgccga gcatctgcag cgcgaggtag ggcaggaaca gccgctcgac gcggtgctcg
    13561 cccagccagg acagcagctc caccggttcg cgccgcagcc gctccggcat gatcaccagg
    13621 gtgccgccgc cgcgcagcgt cccgaggacc tcctggaagg agacgtcgaa gttcagcggc
    13681 gcgaactggg ccgtgcgcag gtcggggcgc ggcgagtgcc cggcctgcca gccgaccatc
    13741 gtgtccaggc accggtggcc gaccgtcacg cccttgggcc agcccgtcga gccggacgtg
    13801 tagatgatgt agacggccag gtccggatcg cacggccgcg tcgccggttc cgcgcgcacg
    13861 tccggccccg gaatcgggac gctctccccc agataaggcg tgtcgccgtg gctcagcagc
    13921 aggcgcggcg tgcagtccgc gaccatgtgc tccagccgcc gcaccgggta ctccgggtcc
    13981 agcgggacgt aggtcgcgcc gcgcaggatc gcgccgagca tcgccgcgac ggccgccgcg
    14041 ccgcgcggcg cgcacaccgc gacgcggtcg ccgggcgcga cgccccggtc cgcgagcagg
    14101 tcgcggacgc ccgccgccca cgcgtacagc tcggcgtagg tgaacgcgcg gtccccgtcg
    14161 accagcgcgg tcgcgtcggg acggcccgcg gcggtctcta acagggcgtc gaccaggcag
    14221 ggcgcggcgg acggcccgcc ccacagcgac gccgagggcg cggcgctcac cgggacaccc
    14281 ccgcccgcag ctcgtccacg gcctccgcga gctccgcgac ggtcgggtgg tcgaagatca
    14341 gccgcatcgg ggcctccagc gcgtactcgc ggtgcagcgc ggcgatgacc ttggtggcgg
    14401 tcatggagtc gccgccgagg tccaggaagt tctcgtcggg ggcgatcccg tcgacgccga
    14461 gcgtcgcctc ccagatcgcg gtgacggtcg cgacggtcgt ggcggtcgtg tcggtcacgg
    14521 catctccttg agttgcgagt cgggctcggc cgtccacgcg gccgccaggc gggtgaagcg
    14581 gtcgcgcagc gtccgggcgg tgtcggcggt gagcacggcg ggcgaggcca gcaggtggcc
    14641 ccggacgccc gcgccgccgc ggacgaggtg gagttcgagt tccagccgcg tcgcggtcgg
    14701 ctcgatcggc cgctcctcga cgcgcaggcc cggcagctcg gggacgccgg gcgcggggcg
    14761 caggtcgaac agcgcctgcg ccagcggcgc gcggcccggc ggccgggcga cgccgctcgc
    14821 ggcgacgacc tggtcgtagg gggcggcgcc gtgctcggac gccgccaggc acacctcgcg
    14881 ggccgcgtcc accgcctcga ccagcgtcgc gtccggcggg cacgcgaccc gcagcggcac
    14941 cgtgttggac aggaagccga ccaaattctg gtcctcggcg cgcagccgcc ccgacgcggc
    15001 ggtcgccagc accgcctcgt cgagtccggc gcggcgggcc aggacggcgg cgtacaggac
    15061 gagcgtcgtc atgtacgccg tgcagcgccg ctccctgctc agccggtcga tgcgcgcggt
    15121 cgtcgcgtcc gacagcgcca ccggcaccgc gtgcgcgccg cccggccccg ccggggcggg
    15181 gtcggcgggc agcgagaccg gcggggcccc ggccagcgtc cgccgccaga actccagcga
    15241 cgccgcgtgg tcgcggcccg cctcccggcg gacgtggtcc aggaagcccg gcgcgggcgg
    15301 caggtcgggt tcctccccgg ccgcgaacgc cgcgtaggcg gcggcgaact cgcggaagaa
    15361 cacctccatc gaccagccgt cgaacgcgat gtggtggatc gtcagcagca gcaccgcgtc
    15421 gtcggcggcg gtccgcagca ggcggacgcg caggaccggt cccgccgcca ggtcgaaccg
    15481 cgccgcccgc tcggcggcga tcacggcgtc gacgtcggcg gcgtccaccg cgtcgaacac
    15541 cgcgccgggc tcgccgacga cctgctcgat gccgccgcgc gccgcgcggt acgtcgtccg
    15601 cagcgcctcg tggcgggcgg cgagccggtc cgccgcgcgg cggaccgcgt cctcgtccac
    15661 cgcgccgcgc aggcggaacg cgcgctggat cacgtacgcg cccggcgcga gctgctcggc
    15721 gagccacagc ctgtgctgcc cgtgggacgc cggtcccacg gctccggcga cggccatcag
    15781 gtcaccggtc ccagccaggc ggcgctgatg cgggcgtggt cggggcccgc gcccgccagc
    15841 gcgtcgacca ggccgctcca gtgcgcgtcc agcgaccgcc acgcgccggt gcagtacacg
    15901 tccgcgaggt cctgggcgtc gggggcgtcc ccggcggcgc gggccagcgt cagcgtcacc
    15961 gtgaccagct cttcgaggat cgcgccgagc agggtgagcg ggcggccgag cccggcgcgc
    16021 tccgccgggt cgggatggtt ccgcagcacg tccgcgcagt gctgggagaa cgtcccgatc
    16081 tgcccggcga gtcgcgccag gtgctcgcgg ttgcgcgcgg tgagctccgg gacgtccggg
    16141 acgtgcgcgc gggcgtcgat ctcgtccggc tccaggcacg ccagcgcgat ccggtcggcg
    16201 agccgcccct gcagcagcac ctccgtgccg cccgcgatgc gcaggccgcg cgcgtcccgg
    16261 tacagccgct ccagcggggc gggcggcgcg ccccgggcgg ccttgccgcg cgccgtctcg
    16321 tagccctccc ccgccatgac cgtcatcgcc cgctcgacga tccgccagca cagcagcgac
    16381 gtgatgtcct tcgccgcgaa ctgctcgggc atcaggttga cgggatcggg gccctggtcg
    16441 cccagcatcg tccagcgcgc ggtggcgtcg agggcgtaca ggtccgccgc cgactccgcg
    16501 acggcccgct ggatctcgtc gtaggtcccg agcgcccggc cgtccaccga ccgccgccgc
    16561 acgtactccc cggtgtgctc cagcgcccgc cgcgccagcg ccagcgcggg cgcggcgatg
    16621 atgtggacgc gcccgcgcga cagcaccgcc gcccgctccg ccgacagcca ctgcccgccc
    16681 tgctcggcca gcaccagctc gcgcggcacc cggacgcccc gcagcgccag cgccccgttg
    16741 gggaacccgc gcaggcccat gaactccagc cgcgcgcgga cctcgaaccc cggcgaggcg
    16801 gtgtcgacga agaagacgcg gggccgcccg tcctccgtcg ccgtcacggc cagcagctcg
    16861 gcgatcgggc cgttgccgat gtagagcttg tcgccgtcca ggacgtaccc gtccgcgtcg
    16921 gcggtcgcgg tggtgaaccg ccgccggttc gccgcgcccg ccggctcggt gtcggccatc
    16981 ccggtgacgg ccccggccgc gagtctcttc atgaccagct cgcggatcgg gccgtccggc
    17041 agcaccggca ggtacgcggc cgcgccgatc ccgttgtgga tggccagcat gaagcccgcg
    17101 ggcagcgcct cgccgctcgc ctcggtgatg acgcggaagg cgttgtaggg cgacagctcc
    17161 cgcccgccga cctcggcggg cgcgagcagg tgcagccagc cgcccgcgcg cagcgcctcg
    17221 gcgaccgtct cgccgtccgg ctcgtccggc agcccggcca gcgccgcgcg gaccccggcg
    17281 acggcggcgt cgcccgccgc ccggtccgcg ccggcctgcg ccgggaacgg gtggaccagg
    17341 tcccacggca ggcggccgtg gcagatctcc tcgaccacgt tcgggacgcc ggggacgctg
    17401 aggctaccgc gcgccatcgc cggcctcccg cgcggccggg cacccggtgg ccggtgctcc
    17461 cgggcccggg tcgccgaacc ggtcgatcag cgccgacagc tcggcgtgcg cgccccggcc
    17521 gctggccgcg aacgagcgga cgacgcgccg ccgggtctcc ggctcctgct cctggctgag
    17581 cttgtacatc ccgtcgacgg actcgacgtg gaactcgaac gcccgcacgc ccggcaggat
    17641 cttgtcgaag tagtcgagcg acccctccgg gtcccagccg gtgccgtggg tgccctcgta
    17701 cgcctcgacg gtccagcgca ccacccgccg cgcgtcctcg ggcgtgtcca gcgggcgcag
    17761 cgtcccgtgg acgtggaccg ccacgaagtc ccaggtcggc gcggcgacgg gcagctcgta
    17821 cacggtcggc gagacgtacc cgtgcgggcc ggtgaacacc agcgtccccg ggccgcccga
    17881 ggcgaccgcc gcccagtgcg ggttcgcggc gttcatgtgg ccgagcagcg tcgcgcccgg
    17941 cagctcggcc gggggccgct cggggtgggt gatgacgggc aggtgggtga tccagggcag
    18001 ggcccgctcg ccgcgggtga cgagcatggc gagcgggttg ctccgcaccg tttcgagtgt
    18061 ccagctccgg ccgcgcggcc ggtactgggg gggaacgaac actggtcctc cgaacgcgtc
    18121 aggatgtcac gagctccacc aggacgccgt ggcagtcctt cgggtgcagg aaggtcgccc
    18181 gcgagcccat cgaggcgggc cgcggcggat cgaacaggac ccgcgggccc gcggcgggca
    18241 gctcggcggc ggcgcggtcc acgtccgggc agccgaacgc gacgtggtgg acgccctcgc
    18301 cgcgcgcggc caggaaccgg cccaccggcg agtccggccg cgtcggcgac aggagctgca
    18361 ggtaggtggc gcggccgtcg tcggtgccgt tgacgcgcag catcgcctcg tggacgccct
    18421 gctcctcgtt ggtctcgcgg tggcacacct cgaagccgaa ggagtcccgg tagaaccgga
    18481 tcgtctcctc caggtcgtgg caggcgatgc cgacgtggtc gacgcgcgtg aacatcacac
    18541 cgccccgacc cgggccccgg cgatggaccg gacgatctcc cccgcgcgga cggcggtgtt
    18601 cgacagcagt tgcgcggaga tcccgtgcgt ctgctcggtg ccgccctgca ggtagatccc
    18661 ggcgcggagc cggtcgtcgg tctccagccg gtagtcgcgg gtgatcgcgg gccgcttgcc
    18721 ggcgtcgcgg cggcagtact cggcgacctc gcccagcacg ttcgcggggt cgatcggccg
    18781 gtagccggtc gcgtacacca ccaggtccac gccgaacgag cgcttctcgc cggtcggcag
    18841 gtgctcgacg tccacgcgca ggccgtcgcc ggtgacgtcc ctgcggacgg cgtgcagccg
    18901 ggaggcgttg agtatccgca gccgctccac gccgcggacc cgctcctggt agacgcgccg
    18961 gtacagctcg tcggccagtt cctggtccac caccgagtag ttcgtgttgc ggtggtagtc
    19021 gaacagcatc cgcttgacgt tctcgggcgc gccgtagaag acgtccacgc tctcggggtc
    19081 gaagatccgg ttcgcgaacg gggtgtcgtc ggcgacgctg tacccgtacc gcaggaagat
    19141 cgcggagacc tccgcgttct cgaaccgccg gtgcaggaac tcggtcgtct cggcggcgct
    19201 ctgccccgcc ccgacgacca ccgcgcggcg cggctcctcg gtcagccgct ccacccgctc
    19261 caggagctgc gcgcagtgcc agatccggtc cccgagctcg atgtcgtcgg gcagcgcggg
    19321 ctcctgcccg acggcgacga cgacgttgcg ggcccgctgg acgcggtgct cgccgccccg
    19381 ccggacgatc acctcgatgt ggtcgccgcc cggccccggg cgcatcgcca cgacctcgct
    19441 gccgtaccgg gcgacgtcct ggaaccgccg cgcgacccat tccaggtagt cgtggaactc
    19501 cacgcgcgag gggaacagcg acttgtggtt gatgaagtcg gccaggcggt cgttgtcgtg
    19561 caggtacgac aggaacccgt attcgctcgc cgggttccgc atcgtgacga ggtccttgat
    19621 gaaggagacc tgcatcgtcg cgccgtcgat gagcatcccg cggtgccagc cgaacgcggg
    19681 ctgcttctcg aagtagacct gcgtgaggtg ttccgcggcg ggccggtcgg cgttgtgctc
    19741 ccggacggcc acggccagcg ccaggttgga cgggccgaag cccaccccga cgatgtccag
    19801 gatgtcgtcg gcgtcggtcg cggggccggt cacagggcca gcccgacgtc gtagcggccc
    19861 agccactcgt tcaggccgag caccatttcg atgctgaacc ggttgacgac ctcggcggcc
    19921 gggccggtcg ggtcctccac gaacgacttg gcggtgccga ggtccagcag gtcgcggacc
    19981 ggcgccttcg ggtccgcgac gacctcggcg aggcgggcgt tgagcagcgc gccgtagcgg
    20041 gggtcgtcgg tgggcgggta gcccgccttc ttgcggtaca gcaccgaggg cggcagcagg
    20101 tcccgcacgg cggcgcgcag caggctcttc tcccggccgt cgaaggtctt catctcccac
    20161 gggacgttga agacgtactc cacgaggcgg tggtcgcaga acgggacgcg gccctccagc
    20221 gcggccgcca tccccatccg gtcccggcgg tccaggatga tccgcaggta gccggtcatg
    20281 ttgaggtagg tgatgcggcg aagctcgcgg tcgatgtcgc tctcgccctc caggacgggg
    20341 acgcccgcga cggccttctc gtactcggcg cgctcgtact cgtcggcctc caggacgtcc
    20401 gcgaggtcgg gggcgagcag gccgctgctg cgcatctggt tcttgccggc catgcggcgc
    20461 gcgaactcca gccacggcat ggtgccctcg ccgcggaacc gctcctcgtg gaaccagtgg
    20521 tagccgccga acagctcgtc cgcgccgtcg ccggtcagcg agacggtgca ttgctcgcgg
    20581 aacgccttgc acagcaggta gagcgaggtg tccaggtccc cgagggacgt ggggtggtcg
    20641 cgggccgtca ggacggtgct gcgcgcctcg gcgtccatga gctggtcggc ggacagttcc
    20701 accgcggtgt gccgcgtccc caggaactcg ctcatgatct tcacgaacgg gaagtcgggg
    20761 gtggcgcgga cctcgtcggg cttgaacgcg tcggcgtggc cggtgaagtt caccgagaac
    20821 gtccgcagct tctcgtccga gccgccggtg cggatcgcca gcgcggccag ggcgctggag
    20881 tccaggccgc cggacaggaa caccccgagc ggcacgtcgg agaccatctg ccggcggacg
    20941 ctgtcctcca gcaggtcccg gacggtgcgg acggtggtgt ccaggtcgtc ggtgtgctcg
    21001 acggcctgca gcgaccagaa ccggctcttg gcgagcccgc cgcgcccgaa gcggacgatc
    21061 gacccggggt cgacctcgaa catccccttg aagatcccgt ggtcggacga cttgacgagg
    21121 gtgacgatcg cccgcaggcc gctctggtcg atctccggcc ggatctgcgg gtgcgcgagg
    21181 atgcccttgg gctcggaccc gaacacgacg ccgccgtcga tctcggcgta gtaaagcggg
    21241 tagatgccga gccggtcgcg gatcagcagc agctcctcgg tccgcgcgtc ccacaccgcg
    21301 aacgcgaaca tcccgagcag ccgctccgcg cagcccgcgc cccactccag gtaggcgcgc
    21361 aggacgacct cggtgtcgct ggtggtctcg aaccggtggc cgcgggcgcc cagctcggcg
    21421 cgcagctcgg ggcagttgaa cacctcgccg gtgtaggcga tggcgaccgg ctcgcggtcg
    21481 ggccgctcgt ccaccatcgg ctgcttgccg cccgccaggt cgatcaccga cagccgccgg
    21541 acgccgaggg cggcgtggcc gtgccgccag acgccgcgct cgtccgggcc ccggcggtgc
    21601 agggtgtcgg tcatcgcctc gatgagcccg gtgtcgtcgg tgtcggcccg ccgccggaaa
    21661 tcgaccagcc ccgtgatgcc acacatggtt gtctcctcgt ttcgcttggt tgccggtcgg
    21721 ccggtcaggc ccggccgcgg gcgagtcctg cggaaagtgc tcggtgaagc tggccgacgc
    21781 tggcgcgggc gcggacggcg cggatcatcg cgggcatcgc gttgcggccg agcgcgacgt
    21841 cgtcggtgag cgcggccagc tcggcggggc ggtcgacgcg cgcgaacggg cggcggcggc
    21901 ccgcggcgac gccggtgcgg agctgctcgc gcatcaggcg gcgctcctcc gcggcgtcct
    21961 cggcgtcggc gacgccgacc cgcgggccgg gcgaggcgta ggccatctcc tcgatctcgc
    22021 cctccagcca gccgctgcgc aggcacgcca gcaggccgtc gcgcttgtcg atctcggtga
    22081 gccagcggtc ggcgtcggcc tcgatctcgt ccacgagccc ggcgatcacg ccggacccgc
    22141 cgagcgggtc gacgtgccgg gccaggtcgg tctcggtcag caggatctgc tggacgcgca
    22201 gcgcgacgcg cgcggcgagc cgcccgggga tctgcgcggc ctcgtcgaac ccgcagacgt
    22261 gcagggactg gacgccgccg aggacggcgg ccacggcctg gacggtggtg cgggcgatgt
    22321 tgttgagcgg ttcggtggcg gccagcgtcg acccgaaggt gttgacctgg atgcgcatcc
    22381 gcatggagcg ggggttgcgc gcgtcgtagc gctcggccat gcgccgcgcg tacatccggc
    22441 gcagcgcgcg gaacttggcg gcctcggcga gcagttccat gtgggtgccg aagatgaagc
    22501 tgagccgggg ggcgacctcg tcgacgccgt agccgcgggc gatcatgtgg tccagatact
    22561 gctcggcgtc ggcgatgccg agggcgacct ccagggcccg gttcgcgccc gcctcccggg
    22621 cgtgcccgcc cgatatcgag atcgggttca ccttcggcag gtgccggacg cagtattcga
    22681 tgacgtcgag cgagaaccgg aaactgtcgt cgaggtcgaa gatgacggca ttccgcgcga
    22741 gatgctcctt taacatctcg ttctgcagtg ttccccggag cgccgccggg tcgacacccg
    22801 attcctcggc cgccacgatc cacatcgcga ggatcatcgg cgcggtcgca ttgatggtgt
    22861 aggcgaccga gacctggtcg agcggaattc cggtgaacac cgacgcgaag tcgtcgacgg
    22921 tcgccaccga gacgccggcc cggccgactt ctccctcggc cgcgggctcg tccgggtcga
    22981 ttcccatctg cgtcggcagg tcgaatgcca gcgacaggcc ggtctcgccg cgttcgagca
    23041 gatagtggaa ccgccggttg gtgtcctcgc cgtcgccgag tccggcgagc tgccggaccg
    23101 tccacggccg ggtggtgtaa ccggtcggat gaatgcccgc ctcgtacggg aactcgcctg
    23161 ggcccgccat ctcagatctc cccgatcagg agcccggacg cctcgaagga ttcgcgcgcg
    23221 ccgggatggt cgaaaacgtc gtgttcggcg aacatccgca gggtgcgccg cgcggcctgg
    23281 cggatctggt cggtctcgaa ccggggcgtg taggtctcgg cgaggacctg ttcggcctgc
    23341 tcggcggtca gtccggcggc gcgcagcgag gtcgtgtgcg cgacggtgtc ggtggccagg
    23401 caggcgcgga ccagggcggg cagcacgcgg gcgacccgct cgcgcacggc cggttccagg
    23461 ccgccccaca ggcggtcgaa gaagatcgtg tagaaggcgt ggtgcagccg ctcgtcgcgg
    23521 gcgtggtcgg cgacgacgtc gcggaccgtg gggacgacct cggcggaccg ggggatggtc
    23581 tccagcagcg aggtcacgac ggtctcgaag atgaccgcct ccagcagccg gccgaggccg
    23641 ggcgcgtccg cgcgcagcgg ctcggtggcg cgggtgagcg cgcccgtcac gggcgcgaac
    23701 gtgtagggca ggtgcggcac cccggtcttg cgttcgacct ggcagacgag gtcgaagttg
    23761 ctcatcgcgt ggtgcgcctc gtcgcagtag atcttccacg cgtcgagccg gacctccgcc
    23821 gggaggccca ggccgaggcc gtcgtcggcg accagcagcg tcgcccggtt gacgaccttg
    23881 gactccaggt tggcgaccga gtccagatag gcgtacagat gccagacgcc gagggataaa
    23941 tgcaactcgt ccggtaactc ggcgaccacg gggtggtcga gatagggcat cagcgaacgg
    24001 gggaagtaac gcatccccgc cggtacctcc gccagcttcc ggtgcggggc gatccgcacc
    24061 cccgcacgtt cgtgccaacg cgagaaaaca gcactgcgat tcaacgtgcc cccgccttcg
    24121 gacaatgacc caaatcgctc ggagatccgc cgcctcat
//
