BGC0001484: 2'-chloropentostatin biosynthetic gene cluster from Actinomadura sp. ATCC 39365
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Location: 1 - 36,432 nt. (total: 36,432 nt).
This entry is originally from NCBI GenBank KP025768.1.

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core biosynthetic genes
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resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001484
Short description 2'-chloropentostatin biosynthetic gene cluster from Actinomadura sp. ATCC 39365
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other
Loci NCBI GenBank: KP025768.1
Compounds
  • 2'-chloropentostatin
  • 2'-amino-2'-deoxyadenosine
Species Actinomadura sp. ATCC 39365 [taxonomy]
References
Chemical products information
2'-chloropentostatin
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C21H27Cl1N10O7
2'-amino-2'-deoxyadenosine
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C10H14N6O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • APC23279.1
1 - 418 (-) hypothetical protein
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  • AKQ99277.1
675 - 2054 (-) pentachlorophenol 4-monooxygenase
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  • AKQ99278.1
2109 - 5162 (-) XRE family transcriptional regulator
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  • AKQ99279.1
5278 - 6060 (-) s-adenosyl methyltransferase
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  • AKQ99280.1
6127 - 6726 (-) bacterial regulatory proteins,tetR family
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  • AKQ99281.1
6843 - 7601 (+) methyltransferase type 11
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  • AKQ99282.1
7673 - 10858 (+) hypothetical protein
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  • AKQ99283.1
10898 - 12337 (-) cation/H(+) antiporter
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  • AKQ99284.1
12392 - 13600 (-) major facilitator superfamily
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  • AKQ99285.1
13672 - 14559 (-) ATP phosphoribosyltransferase
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  • AKQ99286.1
14604 - 15308 (-) short-chain dehydrogenase
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  • AKQ99287.1
15295 - 16014 (-) SAICAR synthetase
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  • AKQ99288.1
16239 - 17516 (+) aminotransferase
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  • AKQ99289.1
17509 - 18564 (+) dehydrogenase
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  • AKQ99290.1
18593 - 20380 (+) ABC transporter,partial
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  • AKQ99291.1
20402 - 22180 (+) ABC transporter
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  • AKQ99292.1
22177 - 22662 (+) NUDIX hydrolase
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  • APC23280.1
22659 - 23396 (-) phosphoribosyl isomerase A
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  • AKQ99293.1
23580 - 24446 (+) ATP phosphoribosyltransferase
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  • AKQ99294.1
24455 - 25249 (+) hydrolase
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  • AKQ99295.1
25374 - 26417 (+) ABC transporter substrate-binding protein
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  • AKQ99296.1
26414 - 27505 (+) sugar ABC transporter permease
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  • AKQ99297.1
27502 - 28722 (+) ABC transporter permease
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  • AKQ99298.1
28722 - 30824 (+) hypothetical protein
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  • AKQ99299.1
30826 - 31737 (+) hypothetical protein
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  • AKQ99300.1
31734 - 32663 (+) pfkB family carbohydrate kinase
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  • AKQ99301.1
32660 - 33385 (+) bacterial regulatory protein,gntR family
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  • AKQ99302.1
33444 - 34139 (+) bacterial regulatory protein,luxR family
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  • AKQ99303.1
34188 - 35120 (+) hypothetical protein
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  • AKQ99304.1
35151 - 35876 (-) alpha/beta hydrolase family
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  • APC23281.1
36063 - >36432 (+) alpha/beta hydrolase
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
Similar known gene clusters
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