BGC0001509: anikasin biosynthetic gene cluster from Pseudomonas fluorescens
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Location: 116,447 - 161,212 nt. (total: 44,766 nt).
This entry is originally from NCBI GenBank NZ_LVEJ01000013.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001509
Short description anikasin biosynthetic gene cluster from Pseudomonas fluorescens
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: NZ_LVEJ01000013.1
Compounds
  • anikasin
Species Pseudomonas fluorescens [taxonomy]
References
Chemical products information
anikasin
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • A8O26_RS13955
  • WP_064118557.1
116447 - 118405 (-) MacB family efflux pump subunit
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  • A8O26_RS13960
  • WP_064118558.1
  • macA
118408 - 119556 (-) macrolide transporter subunit MacA
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  • A8O26_RS13965
  • WP_064118559.1
119623 - 137451 (-) non-ribosomal peptide synthase/polyketide synthase
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  • A8O26_RS13970
  • WP_064118560.1
137448 - 150464 (-) non-ribosomal peptide synthetase
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  • A8O26_RS13975
  • WP_064118561.1
150721 - 157131 (-) non-ribosomal peptide synthetase
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  • A8O26_RS13980
  • WP_064118562.1
157608 - 158402 (+) helix-turn-helix transcriptional regulator
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  • A8O26_RS13985
  • WP_064118563.1
158577 - 159971 (+) efflux transporter outer membrane subunit
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  • A8O26_RS13990
  • WP_008079652.1
160128 - 160733 (+) SCO family protein
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  • A8O26_RS13995
  • WP_064118564.1
160733 - 161212 (+) copper chaperone PCu(A)C
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
A8O26_RS13965
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: threonine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
A8O26_RS13970
Module ?
Specificity: serine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: serine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
A8O26_RS13975
Module ?
Specificity: isoleucine
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Module ?
Specificity: aspartic acid
Evidence for specificity:
  • Structure-based inference
  • Mass spectrometry
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
  • Added NRP substrate specificities
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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