BGC0001511: ansamitocin P-3 biosynthetic gene cluster from Actinosynnema pretiosum subsp. pretiosum
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Location: 1 - 82,944 nt. (total: 82,944 nt).
This entry is originally from NCBI GenBank KY489977.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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TTA codons
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Gene details
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001511
Short description ansamitocin P-3 biosynthetic gene cluster from Actinosynnema pretiosum subsp. pretiosum
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KY489977.1
Compounds
  • ansamitocin P-3
Species Actinosynnema pretiosum subsp. pretiosum [taxonomy]
References
Chemical products information
ansamitocin P-3
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C32H43Cl1N2O9
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AQZ37086.1
 2239 - 3120 (-) oxidoreductase
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  • AQZ37087.1
 3191 - 3787 (+) TetR-family transcriptional regulator
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  • AQZ37088.1
 4039 - 4305 (+) hypothetical protein
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  • AQZ37089.1
 4349 - 6601 (+) ABC transporter transmembrane region protein
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  • AQZ37090.1
 6610 - 7860 (+) Na+/H+ antiporter
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  • AQZ37091.1
 7959 - 8609 (-) hypothetical protein
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  • AQZ37092.1
 8779 - 9825 (-) O-methyltransferase family 2
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  • AQZ37093.1
 10015 - 13191 (+) LuxR-family transcriptional regulator
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  • AQZ37094.1
 13402 - 18195 (+) polyketide synthase
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  • AQZ37095.1
 18205 - 28224 (+) polyketide synthase
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  • AQZ37096.1
 28226 - 29005 (+) N-acetyltransferase
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  • AQZ37097.1
 29096 - 29992 (-) N-methyltransferase
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  • AQZ37098.1
 29989 - 31524 (-) epoxidase
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  • AQZ37099.1
 31536 - 32861 (-) halogenase
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  • AQZ37100.1
 33118 - 34113 (+) 3-hydroxybutyryl-CoA dehydrogenase
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  • AQZ37101.1
 34110 - 34382 (+) acyl carrier protein
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  • AQZ37102.1
 34387 - 35490 (+) butyryl-CoA dehydrogenase
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  • AQZ37103.1
 35601 - 36866 (+) FkbH
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  • AQZ37104.1
 36859 - 37521 (+) O-methyltransferase
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  • AQZ37105.1
 37699 - 40458 (+) transcriptional activator
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  • AQZ37106.1
 40550 - 41620 (+) acyltransferase MdmB
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  • AQZ37107.1
 41635 - 41982 (-) hypothetical protein
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  • AQZ37108.1
 42212 - 44224 (+) carbamoyltransferase
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  • AQZ37109.1
 44620 - 44985 (+) hypothetical protein
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  • AQZ37110.1
 45362 - 45547 (+) mobile element protein
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  • AQZ37111.1
 45953 - 46396 (-) 3-dehydroquinate dehydratase II
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  • AQZ37112.1
 46608 - 47774 (+) lipopolysaccharide biosynthesis protein RffA
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  • AQZ37113.1
 47963 - 61690 (+) polyketide synthase
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  • AQZ37114.1
 61687 - 71115 (+) polyketide synthase
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  • AQZ37115.1
 71192 - 72400 (+) glycosyltransferase
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  • AQZ37116.1
 72668 - 73693 (+) 3-oxoacyl-[acyl-carrier protein] reductase
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  • AQZ37117.1
 73773 - 74237 (-) hypothetical protein
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  • AQZ37118.1
 74419 - 75039 (-) transcriptional regulator TetR family
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  • AQZ37119.1
 75064 - 75657 (+) cytochrome P450
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  • AQZ37120.1
 76848 - 76976 (+) hypothetical protein
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  • AQZ37121.1
 77013 - 78002 (-) RNA polymerase sigma factor
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  • AQZ37122.1
 78227 - 78859 (-) putative methyltransferase
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  • AQZ37123.1
 78974 - 79447 (+) Na+/H+ antiporter NhaA type
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  • AQZ37124.1
 79447 - 79743 (+) Na+/H+ antiporter
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  • AQZ37125.1
 79728 - 80303 (-) dihydrofolate reductase
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  • AQZ37126.1
 80390 - 81004 (+) transcriptional regulator TetR family
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  • AQZ37127.1
 81256 - 82941 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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