BGC0001568: cytorhodin biosynthetic gene cluster from Streptomyces sp. SCSIO 1666
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Location: 1 - 58,217 nt. (total: 58,217 nt).
This entry is originally from NCBI GenBank MF773975.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
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resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001568
Short description cytorhodin biosynthetic gene cluster from Streptomyces sp. SCSIO 1666
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: MF773975.1
Compounds
  • cytorhodin
Species Streptomyces sp. SCSIO 1666 [taxonomy]
References
Chemical products information
cytorhodin
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C48H68N2O15
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ATJ00741.1
1 - 1428 (-) ribonuclease BN
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  • ATJ00742.1
1617 - 1892 (-) hypothetical protein
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  • ATJ00743.1
2116 - 2718 (-) CytR4
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  • ATJ00744.1
2743 - 3291 (-) DinB family protein
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  • ATJ00745.1
3458 - 5743 (-) ABC transporter
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  • ATJ00746.1
5797 - 6321 (-) glutathione peroxidase
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  • ATJ00747.1
6529 - 7359 (-) ABC-2 type transporter
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  • ATJ00748.1
7359 - 8345 (-) ABC transporter
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  • ATJ00749.1
8421 - 9404 (-) dTDP-glucose 4,6-dehydratase
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  • ATJ00750.1
9426 - 10706 (-) glycosyl transferase family 28
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  • ATJ00751.1
10741 - 11991 (-) cytochrome P450 like protein
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  • ATJ00752.1
12121 - 13173 (-) polyketide synthase
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  • ATJ00753.1
13170 - 14204 (-) 3-oxoacyl-ACP synthase
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  • ATJ00754.1
14201 - 15445 (-) beta-ketoacyl synthase
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  • ATJ00755.1
15442 - 16710 (-) beta-ACP synthase
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  • ATJ00756.1
16707 - 17042 (-) antibiotic biosynthesis monooxygenase
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  • ATJ00757.1
17158 - 18138 (-) ornithine cyclodeaminase
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  • ATJ00758.1
18428 - 18991 (-) PadR-like family transcriptional regulator
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  • ATJ00759.1
19287 - 20579 (+) glycosyl transferase family 28
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  • ATJ00760.1
20648 - 21274 (+) dTDP-4-dehydrorhamnose 3,5-epimerase
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  • ATJ00761.1
21241 - 22278 (+) NAD-dependent epimerase
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  • ATJ00762.1
22275 - 23732 (+) NDP-hexose 2,3-dehydratase
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  • ATJ00763.1
23897 - 24043 (-) toxin-antitoxin system antitoxin
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  • ATJ00764.1
24443 - 25282 (+) transposase
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  • ATJ00765.1
25340 - 26449 (-) NDP-hexose aminotransferase
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  • ATJ00766.1
26446 - 27174 (-) SAM-dependent methyltransferase
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  • ATJ00767.1
27230 - 28009 (-) cyclase
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  • ATJ00768.1
28156 - 28563 (+) hydroxylacyl-CoA dehydrogenase/cyclase
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  • ATJ00769.1
28604 - 29350 (+) C-7 ketoreductase
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  • ATJ00770.1
29592 - 30950 (-) aromatase
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  • ATJ00771.1
30959 - 31744 (-) ketoacyl reductase
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  • ATJ00772.1
31752 - 33053 (-) RfbH/ NDP-hexose 3,4-dehydratase
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  • ATJ00773.1
33064 - 34383 (-) glycosyl transferase
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  • ATJ00774.1
34380 - 35510 (-) cytochrome P450 like protein
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  • ATJ00775.1
35673 - 36713 (+) NDP-hexose-3-ketoreductase
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  • ATJ00776.1
36804 - 38399 (-) FAD-dependent oxidoreductase
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  • ATJ00777.1
38396 - 39193 (-) SAM-dependent methyltransferase
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  • ATJ00778.1
39190 - 40086 (-) alpha/beta hydrolase esterase
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  • ATJ00779.1
40091 - 41194 (-) O-methyltransferase
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  • ATJ00780.1
41234 - 41671 (-) aklanonic acid methyl ester cyclase
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  • ATJ00781.1
41859 - 42716 (+) methyltransferase
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  • ATJ00782.1
42828 - 43715 (-) transcriptional regulator
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  • ATJ00783.1
43869 - 44123 (-) acyl carrier protein
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  • ATJ00784.1
44410 - 45285 (+) glucose-1-phosphate thythymidylyltransferase
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  • ATJ00785.1
45346 - 46200 (-) aldo/keto reductase
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  • ATJ00786.1
46227 - 47837 (-) FAD-linked oxidase
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  • ATJ00787.1
48020 - 48469 (-) nitroreductase family deazaflavin dependent oxidoreductase
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  • ATJ00788.1
48551 - 49441 (-) MarR family transcriptional regulator
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  • ATJ00789.1
49507 - 50247 (+) hypothetical protein
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  • ATJ00790.1
50244 - 51023 (+) hypothetical protein
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  • ATJ00791.1
51501 - 58217 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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