BGC0001584: C-1027 biosynthetic gene cluster from Streptomyces sp. CB02366
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Location: 1 - 73,117 nt. (total: 73,117 nt).
This entry is originally from NCBI GenBank KU597647.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
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NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001584
Short description C-1027 biosynthetic gene cluster from Streptomyces sp. CB02366
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Polyketide
Loci NCBI GenBank: KU597647.1
Compounds
  • C-1027
Species Streptomyces sp. CB02366 [taxonomy]
References
Chemical products information
C-1027
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C43H42Cl1N3O13
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ANY94423.1
 121 - 1491 (+) glycerol phosphate ABC transporter
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  • ANY94424.1
 1631 - 3958 (-) UvrA-like drug resistance pump
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  • ANY94425.1
 4038 - 5423 (-) Na/H efflux pump
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  • ANY94426.1
 5410 - 6894 (-) alkylhalidase
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  • ANY94427.1
 7077 - 8144 (+) dNTP-glucose synthase
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  • ANY94428.1
 8277 - 8708 (-) apoprotein
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  • ANY94429.1
 8755 - 9987 (-) amino transferase
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  • ANY94430.1
 9984 - 10718 (-) N-methyl transferase
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  • ANY94431.1
 10718 - 11989 (-) C-methyltransferase
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  • ANY94432.1
 12095 - 13252 (-) epoxide hydrolase
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  • ANY94433.1
 13325 - 13987 (-) anthranilate synthase II
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  • ANY94434.1
 13984 - 15465 (-) anthranilate synthase I
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  • ANY94435.1
 15481 - 16935 (-) phenylacetyl CoA ligase
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  • ANY94436.1
 16932 - 17603 (-) 2-amino-4-deoxychorismate dehydrogenase
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  • ANY94437.1
 17622 - 18944 (-) 3-O-acyltransferase
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  • ANY94438.1
 19043 - 19621 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
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  • ANY94439.1
 19872 - 21218 (+) FAD-binding monooxygenase
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  • ANY94440.1
 21262 - 22644 (+) glycosyl transferase
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  • ANY94441.1
 22647 - 23639 (+) dNTP-glucose dehydratase
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  • ANY94442.1
 23683 - 25248 (+) transmembrane efflux protein
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  • ANY94443.1
 25331 - 26641 (+) coenzyme F390 synthase-like protein
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  • ANY94444.1
 26861 - 28444 (+) chlorophenol-4-monooxygenase
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  • ANY94445.1
 28529 - 29365 (-) hydrolase
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  • ANY94446.1
 29587 - 30009 (-) hypothetical protein
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  • ANY94447.1
 30236 - 31561 (+) citrate/shikimate transporter
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  • ANY94448.1
 31630 - 33012 (+) C-domain type II peptide synthetase
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  • ANY94449.1
 33057 - 33338 (+) type II PCP
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  • ANY94450.1
 33442 - 35061 (-) MIO-dependent tyrosine 2,3-aminomutase
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  • ANY94451.1
 35130 - 37778 (-) A-domain type II peptide synthetase
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  • ANY94452.1
 37993 - 40101 (+) antibiotic transporter
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  • ANY94453.1
 40206 - 41255 (+) O-methyltransferase
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  • ANY94454.1
 41311 - 42573 (+) P450 hydroxylase
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  • ANY94455.1
 42640 - 43821 (-) oxidoreductase
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  • ANY94456.1
 44473 - 45501 (+) hypothetical protein
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  • ANY94457.1
 45526 - 46446 (-) oxidoreductase
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  • ANY94458.1
 46471 - 47022 (-) alkylhydroperoxidase
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  • ANY94459.1
 47345 - 47962 (-) hypothetical protein
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  • ANY94460.1
 48237 - 49478 (+) regulator
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  • ANY94461.1
 50018 - 51001 (+) oxidase
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  • ANY94462.1
 51055 - 51858 (-) hypothetical protein
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  • ANY94463.1
 52096 - 52566 (-) type II thioesterase
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  • ANY94464.1
 52706 - 54361 (-) oxidoreductase
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  • ANY94465.1
 54358 - 54948 (-) hypothetical protein
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  • ANY94466.1
 55206 - 56285 (+) regulatory protein
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  • ANY94467.1
 56311 - 57165 (+) AraC family transcriptional regulator
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  • ANY94468.1
 57053 - 58402 (-) cytochrome P450
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  • ANY94469.1
 58399 - 58947 (-) flavin reductase
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  • ANY94470.1
 59076 - 64895 (-) enediyne polyketide synthase
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  • ANY94471.1
 64892 - 66031 (-) hypothetical protein
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  • ANY94472.1
 66028 - 67896 (-) hypothetical protein
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  • ANY94473.1
 67953 - 68930 (-) hypothetical protein
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  • ANY94474.1
 69035 - 69979 (-) hypothetical protein
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  • ANY94475.1
 70224 - 70667 (-) HxlR family transcriptional regulator
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  • ANY94476.1
 70814 - 71377 (+) hypothetical protein
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  • ANY94477.1
 71382 - 71852 (+) hypothetical protein
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  • ANY94478.1
 71930 - 73117 (-) transcriptional regulator
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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