LOCUS       BGC0001587              8255 bp    DNA     linear   BCT 04-FEB-2015
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893 DNA, complete genome.
ACCESSION   BGC0001587
VERSION     BGC0001587
KEYWORDS    .
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     [WARNING] On Mar 24, 2016 this sequence was replaced by BA000030.4.
            On Jun 15, 2007 this sequence version replaced BA000030.2.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 02:43:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6792145
            Orig. end    :: 6800400
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     subregion       1..8255
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="Other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..8255
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(7..1035)
                     /locus_tag="SAV_5615"
     CDS             complement(7..1035)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 282.9; E-value:
                     4.1e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SAV_5615"
                     /note="PF00291: Pyridoxal-phosphate dependent enzyme;
                     putative cysteine synthase (O-acetylserine sulfhydylase)"
                     /product="putative cysteine synthase"
                     /protein_id="BAC73327.1"
                     /transl_table=11
                     /translation="MPGSLRRPSVVSRVSDLIGYTPLLELAATETGSRLLLKLEMFNPT
                     GTAKIRMARQMITDAEERGELRAGGRIIESTSGNTGLGLAVIAAERGYTFTAVVDNHAA
                     VDKLRAMKALGAELVHVVDDGTDELATAAREELAEEMARGQDNTIFTEQHNNPSNGVGY
                     FPVAHELHEALDGRLDVLVGAVGTGGGLCGTARELRTLIPGFTTIGVEPKGSIAFGGPA
                     HDYYQSGTGTPEGAPIGALVDFGLIDEGAKVGDVEAFATCRAVARTGLLIGGSAGGVVH
                     EALTRLPGLPPGTTMVALINDGGEKYMDTVFNDDWMRARDLLDPAAEREVDELLTKLRG
                     NR"
     gene            complement(1078..2451)
                     /locus_tag="SAV_5616"
     CDS             complement(1078..2451)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 149.1;
                     E-value: 2.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SAV_5616"
                     /note="PF02784: Pyridoxal-dependent decarboxylase,
                     pyridoxal binding domain"
                     /product="putative amino acid decarboxylase"
                     /protein_id="BAC73328.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 5.5e-20, bitscore:
                     61.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTGPPALPTLPALPDPAADAVLGSGLLEELAYALGGPFHFLLP
                     DAFDANLRALHSVLDETGVDGFVYFAKKANKAAVWAERSAAGGAGVDVASAAELRQALG
                     HGVRGEHLVVTGPAKDLALLGLAVRHGALIAVDALDELDTLITTVSGDRTRPARLLLRC
                     LPPAQPHSRFGLGEAEVALALERCVTAGEAVRMEGFSFHLSGYDVKLRADLAGHLVELC
                     LKARVLGLEADRISIGGGLPVSYSSAADWNTFLTRQNGGHYHADRTFDPDGFYPYHSPV
                     AGADALRRILATRPEGHRPSLAALLNDAGITLLLEPGRALLDRAGGTVFRVQGVKDRDG
                     YQLLTVNGTSLSLSEQWFNSEYLPDPHLLSAHPDTPDAVWPAAVGAATCLESDMLTWRK
                     VPFPRRPRTGDLLVYPNTAGYQMDSNESPFHDLALPPKVVIDHTDRARPRWRLDRHAP"
     gene            complement(2442..3473)
                     /gene="arcB3"
                     /locus_tag="SAV_5617"
     CDS             complement(2442..3473)
                     /codon_start=1
                     /gene="arcB3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158:ornithine cyclodeaminase (Score: 185.4; E-value:
                     1.9e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SAV_5617"
                     /note="PF02423: Ornithine cyclodeaminase/mu-crystallin
                     family"
                     /product="putative ornithine cyclodeaminase"
                     /protein_id="BAC73329.1"
                     /transl_table=11
                     /translation="MTMPDASTTAAAEPIPRADRHLRILSTGDLAGIDISLADVVSTVE
                     DAYRTLHAGESDNPRKLTVKPRDGHSVAYAMLGRDGSRDVVAVKTSYKHGLDKGREEQH
                     YYTTLTLYDDVTGLPVAMMDCSRIGSLRTPAVSALLARECAAPGARSALVIGTGTQGRL
                     ALPFLLTTLPGLDRLMLFGTHPEGVTAVRERLRAHFPDRDVEIVTDAGAAASEADIIVA
                     TAGGHTPAAVGADRLKPGSLSILVGHGLAPSALHRADRVIATSEAQMKVTGIDMADADG
                     ELRAVDAEFPPVITGDTAGRRTATERIFAYNSGLVVTDIALGHRFAQLALEQGLGTEVA
                     LWR"
     gene            complement(3496..4488)
                     /locus_tag="SAV_5618"
     CDS             complement(3496..4488)
                     /codon_start=1
                     /locus_tag="SAV_5618"
                     /note="PF02668: Taurine catabolism dioxygenase TauD, TfdA
                     family, putative IdeR-binding site:
                     TTAGGTTAGGCATACCTAA(6796788:6796806)"
                     /product="putative oxygenase"
                     /protein_id="BAC73330.1"
                     /transl_table=11
                     /translation="MSTAAAPARQLDPDSVSELRQATEHIHAEFGTSATTPALLKRIAT
                     TANAFGDGLRHHCRPVDTDDGLFVLRGLDIDDAAAGPTPDSWATAGDSGAAHDITLLLL
                     ATVMGNPIAWEGQQDGRFVHNIVPSPGHETEQTGASSTVLLSPHTEDAFHPGRAHLLML
                     GCMRNHDDIATTAASVRKTRLSERDVRTLTRPVLPILPDDAYAEAQGYAEEPPPVPALF
                     ASEDGITLRFDPAYTPLDQADDAYRSAYGRLGEELARVSVAVSLAPGEVLVVDNDLVVH
                     GRVPFQARYDGTDRWLKRASVRVPGRRTRPLTEAHEHGYGQSAIEAHAR"
     gene            4859..6409
                     /gene="oppA8"
                     /locus_tag="SAV_5619"
     CDS             4859..6409
                     /codon_start=1
                     /gene="oppA8"
                     /gene_functions="transport (smcogs) SMCOG1068:extracellular
                     solute-binding protein family 5 (Score: 311.4; E-value:
                     2.1e-94)"
                     /gene_kind="transport"
                     /locus_tag="SAV_5619"
                     /note="putative IdeR-binding site:
                     TTAGGGTAGGCAAACCTAA(6796946:6796964), PF00496: Bacterial
                     extracellular solute-binding proteins, family 5 Middle"
                     /product="putative peptide ABC transporter solute-binding
                     protein"
                     /protein_id="BAC73331.1"
                     /transl_table=11
                     /translation="MNINRRQVLLAGGAMGASALLAACSGGGDDTSAASSDKGGKPRKG
                     GTLRIGALGRAGAITRDPHGTQGNESDYLILALVYDTLTVPGADPNTKPRLAASWEPSK
                     DLKTWRFKLAEDAAFHDGSPVTADDVVWSLRRLRNTPSGAARLPGIKAENITADGKDTV
                     VLVSDYANAELPPLTRLTTFVLKKGTSDKELAKAPGTGPFKLDRYRAGNARLVRNDQWY
                     GGTVYLDAIEVTMFETPQAMANALLAGQIDVASNAGAVAARTAKSRKDVQVVRRPDDMS
                     MPLVMRTADGPFADARVREAMRLVVDREAMVKQVLSGYGTVANDIMGTGDPGYAKDVPQ
                     RERDLAEAERLLSEAKFDLSKTYELVTTEDISGLAESATLFASQAREAGIKIKVVKQES
                     GAFYEKTWLKGDLYTTYWGTNDSVVFFASKTLVSEAGQNEAGFADKKFDATYRKVIATA
                     DPKARAEVLKELQRIEYDRSGYLLWGMADGIDLAASKVRGLPELAGYGRVQLENVWLG"
     gene            6523..7413
                     /gene="oppB8"
                     /locus_tag="SAV_5620"
     CDS             6523..7413
                     /codon_start=1
                     /gene="oppB8"
                     /gene_functions="transport (smcogs)
                     SMCOG1118:binding-protein-dependent transport systems
                     (Score: 274.8; E-value: 1.4e-83)"
                     /gene_kind="transport"
                     /locus_tag="SAV_5620"
                     /note="PF00528: Binding-protein-dependent transport system
                     inner membrane component"
                     /product="putative peptide ABC transporter permease
                     protein"
                     /protein_id="BAC73332.1"
                     /transl_table=11
                     /translation="MLAILIAAVFAAVELLPGDAANATSERGDSAADVAARRHLLGLDR
                     PLWERFADWMTGLPTGDLGTSARGQKVTDLLADPFPNTLLLATVAFVLTAALSLALGCW
                     TAARPGSMTDRIVGHAATSAFAIPEFVVSVGLLIVLSLWTGWLPAVTLTGADGAPATWT
                     MLIMPALALVIPQTGWNTTIVRGALADQAATPHVEAAQLDGLSPHRVIWRHALPGAVPA
                     VATGLATSTGMLLGGAVVVETLFNYPGIGSVLAGAVANRDTPLIAGVVVCAGAAISLVL
                     LAADVIRARVLGASS"
ORIGIN
        1 tgagggtcat cggttcccgc ggagcttggt gaggagttcg tcgacttccc gttccgccgc
       61 gggatcgagg aggtcgcggg cccgcatcca gtcgtcgttg aagacggtgt ccatgtactt
      121 ctccccgccg tcattgatca gggcgaccat agtcgtgccg ggcggaagtc cgggcaggcg
      181 ggtcagggct tcgtggacga cgccgccggc ggagcccccg atgagcaggc cggtgcgggc
      241 cacggcccgg caggtggcga acgcctcgac gtcaccgacc ttggcccctt cgtcgatgag
      301 gccgaagtcg accagagcac cgatcggggc gccctcgggc gtgccggtgc ccgactggta
      361 gtagtcgtgc gccgggccgc cgaacgcgat cgaccccttc ggttcgacgc cgatggtggt
      421 gaagccgggt atgagggtgc gcagttcacg ggccgtgccg cacaggccgc cgccggtgcc
      481 gacggccccg acgaggacgt cgaggcggcc gtcgagtgcc tcgtggagtt cgtgggcgac
      541 ggggaagtag ccgacgccgt tgctggggtt gttgtgctgc tcggtgaaga tggtgttgtc
      601 ctggccgcgc gccatctcct cggcgagttc ctcacgggcg gcggtggcga gttcgtcggt
      661 tccgtcgtcc acgacgtgga ccagttcggc gcccagggcc ttcatggccc gcagcttgtc
      721 gacggcggcg tggttgtcga cgacggcggt gaaggtgtag ccgcgttcgg cggcgatgac
      781 ggccaggccc aggccggtgt tgccggaggt ggactcgatg atccggcctc ccgcgcgcag
      841 ttcgccgcgc tcctcggcat cggtgatcat ctggcgggcc atgcggatct tcgcggtgcc
      901 ggtggggttg aacatctcca gcttcagcag caggcggctg ccggtctccg tggccgcgag
      961 ttccagcagc ggggtgtagc cgatgaggtc ggacacgcgg gagaccacgg acgggcgccg
     1021 cagggatccg ggcatcgaaa ttctcctggg gaatcggtgg gggacgtcgg ctcgggatca
     1081 gggggcgtga cggtcgaggc gccagcgcgg gcgggcccgg tcggtgtggt cgatgaccac
     1141 cttgggcggc agcgccaggt cgtggaaggg ggactcgttg gagtccatct ggtagccggc
     1201 ggtgttcggg tagaccagca ggtccccggt gcgcggtctg cgggggaagg ggaccttgcg
     1261 ccacgtgagc atgtccgatt ccaggcaggt cgcggcgccc acggcggccg gccacaccgc
     1321 gtccggtgtg tcggggtggg ctgacagcag gtgcgggtcg ggcaggtact cgctgttgaa
     1381 ccactgctcg gacaggctca ggctggtgcc gttcaccgtc aggagctggt atccgtcccg
     1441 gtccttgacc ccctggacac ggaagacggt gccgccggcc cggtcgagca gagcgcgtcc
     1501 gggctccagc agaagcgtga tgccggcgtc gttcagcagc gccgcgaggc ttggacggtg
     1561 cccttcgggg cgcgtggcca ggatccggcg cagggcgtcc gccccggcga ccggtgagtg
     1621 gtaggggtag aagccgtcgg ggtcgaacgt cctgtccgcg tggtagtggc cgccgttctg
     1681 tcgcgtcagg aaggtgttcc agtcggcggc ggagctgtag ctgaccggca ggccgccgcc
     1741 gatgctgatg cggtcggcct ccagtccgag gacgcgggcc ttgaggcaca gttcgacgag
     1801 gtgcccggcc aggtcggcgc ggagcttcac gtcgtatccg gacaggtgga agctgaagcc
     1861 ctccatacgg accgcttcgc ccgccgtgac acagcgctcc agggcgaggg ccacttcggc
     1921 ctcgcccagg ccgaaacggc tgtggggctg agcgggcggc aggcagcgca gcagcagccg
     1981 ggccgggcgc gtgcggtccc cggacacggt ggtgatgagc gtgtcgagtt cgtcgagcgc
     2041 gtccacggcg atcagggcac cgtgccggac ggccagtccc agcagtgcca agtccttggc
     2101 cggaccggtg accacgaggt gctccccgcg cacaccgtgc cccagggcct ggcgcagttc
     2161 ggcggcggaa gcgacgtcga ctcccgcccc gccggcggcg gatcgttccg cccacacggc
     2221 tgccttgttg gccttcttcg cgaagtacac gaaaccgtcg acgccggtct cgtcgaggac
     2281 gctgtgcagg gcgcgcaggt tggcgtcgaa ggcgtcgggc agcaggaagt ggaacgggcc
     2341 gccgagcgcg taggcgagtt cctccagcag cccgctgccc agcacggcgt cggcggccgg
     2401 gtcgggcagg gcgggaaggg tgggaagggc ggggggcccg gtcaccgcca cagtgccacc
     2461 tcggtgccca ggccctgttc gagggcgagc tgtgcgaagc ggtgccccag cgcgatatcg
     2521 gtgacgacga gtccgctgtt gtaggcgaag atccgctccg tcgcggtgcg gcggcccgcg
     2581 gtgtcgccgg tgatcacggg cgggaactcg gcgtcgaccg cgcggagttc gccgtcggcg
     2641 tcggccatgt cgatgccggt gaccttcatc tgggcctcgc tggtggcgat cacccggtcg
     2701 gcccggtgca gggccgacgg ggcgagaccg tggcccacga ggatggacag ggagcccggc
     2761 ttgagccggt ccgccccgac cgcggccggg gtgtggccgc cggccgtggc cacgatgatg
     2821 tcggcctccg aggccgcggc ccccgcgtcg gtgacgatct ccacgtcccg gtccgggaag
     2881 tgcgcccgaa gccgctcgcg caccgcggtg acgccctcgg ggtgggtgcc gaagagcatc
     2941 agccggtcca gcccgggcag cgtcgtcagc aggaagggca gcgccagacg gccctgggtg
     3001 cccgtaccga tgaccagggc gctgcgcgca ccgggggcgg cgcattcgcg ggccagcagc
     3061 gcggagaccg ccggggtgcg cagcgatccg atccgggagc agtccatcat cgccacgggc
     3121 agcccggtga catcgtcgta gagggtcagc gtggtgtagt agtgctgctc ctcgcgcccc
     3181 ttgtccaggc cgtgcttgta ggaggtcttg acggcgacga cgtcgcggga gccgtcccgg
     3241 ccgagcatcg cgtacgcgac cgaatgcccg tcccgcggct tgacggtgag cttgcggggg
     3301 ttgtcggact caccggcgtg cagggtgcgg taggcgtcct ccacggtgga caccacgtcg
     3361 gccagggaga tgtcgatccc ggccagatcg ccggtcgaga ggatccgcag gtgccggtcg
     3421 gcgcggggta tcggttcggc ggcggcggtg gtcgaggcgt caggcatggt cattcctcca
     3481 ggaacggggc ggggttcagc gcgcgtgggc ttcgatcgcg ctctggccgt agccgtgctc
     3541 gtgggcttct gtcagggggc gggtgcggcg cccgggaacg cggacggagg cgcgcttgag
     3601 ccaccggtcg gtgccgtcgt agcgggcctg gaagggaaca cggccgtgga cgaccaggtc
     3661 gttgtcgacg accaggacct caccgggagc gaggctgacc gcgacggaga cacgggccag
     3721 ttcttccccg agccgcccgt acgcgctccg gtaggcgtcg tccgcctggt cgaggggggt
     3781 gtaggcgggg tcgaagcgca gcgtgatccc gtcctcgctc gcgaacaggg cgggcacggg
     3841 cggcggctcc tcggcgtagc cctgggcctc ggcgtaggcg tcgtccggca ggatggggag
     3901 caccgggcgg gtcagggtgc gcacgtcccg ctccgacagc cgcgtcttgc ggacgctcgc
     3961 cgcggtggtg gcgatgtcgt cgtggttgcg catgcagccg agcatcagca ggtgggcgcg
     4021 gccggggtgg aaggcgtcct cggtgtgggg gctgagcagc acggtgctgc tggcgccggt
     4081 ctgctcggtc tcgtggccgg gcgagggcac gatgttgtgg acgaagcggc cgtcctgctg
     4141 cccctcccag gcgatcgggt tgcccatcac ggtggccagc agcaggagcg tgatgtcgtg
     4201 ggccgctccg ctgtctccgg ccgtggccca gctgtccggc gtcggaccgg ccgcggcgtc
     4261 gtcgatgtcg aggccgcgca ggacgaacag tccgtcgtcg gtgtcgacgg ggcggcagtg
     4321 gtgacgcagg ccgtcgccga acgcgttcgc ggtcgtcgcg atccgcttca gcagcgcggg
     4381 ggtcgtcgcc gaggtgccga attcggcgtg tatgtgctct gtggcttggc ggagttcact
     4441 cacggagtcg gggtcgagct gacgggcagg tgcggctgcc gtgctcatgg cgaagtggtc
     4501 cgtttcgtgt gggggcaggg gtgtcgggcg ccgtacgtcc tgaaggtgcg gcgacggtca
     4561 accagtagga gggcagcagg agttcggccc acgcggcggg cggctcagct ctcggggggg
     4621 cgttcgaacg ctaacaccga acttaggtta ggcataccta attcacaggc catatgatgt
     4681 ggccggaagc cggcgggggg atgcggcggg gcgcccctgt gaatgcacgc gcccggcgtg
     4741 cgccccgtat gcccagcgcg caccctgcat gccgagatcc ccttgcggga acgattgtca
     4801 ttagggtagg caaacctaag caccactggg gtgctcggga cggggatcgg ggacgtacgt
     4861 gaacatcaac aggcgtcaag tgctgctggc cggcggggcg atgggcgcgt cggcgctgct
     4921 ggccgcctgc tccgggggcg gggacgacac gtcggccgcc tcctccgaca agggcggcaa
     4981 gccccgcaag ggcggcacgc tccgcatcgg ggcgctcggc cgcgccggcg ccatcacccg
     5041 tgacccgcac ggcactcagg gcaacgagag cgactacctg atcctcgccc tcgtctacga
     5101 caccctcacc gtcccgggcg ccgaccccaa caccaagcct cggctggccg cttcgtggga
     5161 gccgtcgaag gacctgaaga cctggcgctt caagctggcc gaggacgccg ccttccacga
     5221 cggcagcccg gtcaccgccg acgacgtcgt gtggtcgctg cggcggctgc gcaacacccc
     5281 ctccggggcc gcccgcctgc ccggcatcaa ggccgagaac atcaccgccg acgggaagga
     5341 cacggtggtg ctggtctccg actacgcgaa cgccgaactc ccgcccctga cccggctgac
     5401 gacgttcgta ctgaagaagg gcacatcgga caaggagttg gcgaaggcgc cgggcaccgg
     5461 gccgttcaag ctcgaccggt accgcgccgg caacgcgcgc ctggtgcgca acgaccagtg
     5521 gtacggcggc accgtgtacc tcgacgcgat cgaggtgacg atgttcgaga cgccgcaggc
     5581 gatggccaac gcgctgctcg ccgggcagat cgacgtcgcc tccaacgcgg gtgcggtcgc
     5641 cgcgcgcacg gcaaagtccc gcaaggacgt ccaggtggtg cgccgccccg acgacatgtc
     5701 gatgcccctc gtcatgcgca ccgcggacgg cccgttcgcc gatgcccggg tgcgggaggc
     5761 gatgcgtctg gtggtggacc gcgaggccat ggtcaagcag gtcctgtccg gatacggaac
     5821 cgtcgccaac gacatcatgg gaaccggcga ccccggctac gccaaggacg tcccgcagcg
     5881 ggagcgtgac ctggccgagg ccgagcggct gctctccgag gcgaagttcg acctgtccaa
     5941 gacctacgag ctggtcacca ccgaggacat ctcggggctc gccgagtccg ccaccctgtt
     6001 cgcctcccag gcccgcgagg ccggaatcaa gatcaaggtc gtcaagcagg agtccggcgc
     6061 gttctacgag aagacctggc tcaagggcga cctctacacg acgtactggg gcaccaacga
     6121 ctcggtggtg ttcttcgcgt ccaagaccct ggtcagcgag gccgggcaga acgaagccgg
     6181 cttcgcggac aagaagttcg acgcgaccta ccgcaaggtg atcgccaccg cggacccgaa
     6241 ggcccgcgcc gaggtactca aggagctcca gcggatcgag tacgaccggt ccggctatct
     6301 gctgtggggc atggccgacg gcatcgacct ggccgcctcc aaggtccgtg gtctgcccga
     6361 gctcgccggc tacggccgcg tccagctcga gaacgtgtgg ctgggttgag ccggttgtcc
     6421 aaggatggcg tgacggccgc cccgccgtgg gcggccaccg tgtcgcgtcg cgtgctgccg
     6481 ccgctcgccc gcgcgggtgc ggcgctggcc cgccgggtac tcatgctcgc gatcctgatc
     6541 gcggccgtgt tcgccgcggt ggagctgttg cccggggacg cggcgaacgc gacctccgag
     6601 cgtggggaca gcgccgcgga tgtcgcggca cgccgtcatc tgctcggcct ggaccggccc
     6661 ctgtgggaac gcttcgccga ctggatgacg ggtctgccca ccggcgacct gggcaccagc
     6721 gcccgcggcc agaaagtcac cgacctgctg gccgacccct ttcccaacac cctgctgctg
     6781 gcgacggtcg ccttcgtcct caccgccgcg ctctcgctgg cgctcggctg ctggaccgcc
     6841 gcccggccgg gctcgatgac cgaccggatc gtcggccacg ccgccacctc ggcgttcgcc
     6901 atccccgaat tcgtcgtctc cgtcggcctg ctcatcgtgc tgtcgctgtg gacgggctgg
     6961 ctgcccgccg tgaccctgac cggtgccgac ggtgcccccg ccacctggac catgctgatc
     7021 atgccggccc tcgcgctggt catcccgcag accggatgga acaccaccat cgtgcgcggg
     7081 gcgctcgccg accaggcggc caccccgcac gtcgaggccg cccagctcga cggcctgtcg
     7141 ccgcaccgcg tcatctggcg ccacgcgctt cccggagccg tcccggccgt cgccaccggc
     7201 ctggccacct ccaccgggat gctgctgggc ggcgcggtgg tggtggagac gctcttcaac
     7261 tacccgggca tcggcagtgt gctggccggc gccgtcgcca accgcgacac ccccctcatc
     7321 gccggcgtcg tcgtctgcgc cggcgccgcc atcagcctgg tcctgctggc cgccgacgtc
     7381 atccgcgccc gagtcctggg agcctcctca tgagcgtcgc cacgacgggc cgcaggccgg
     7441 ccacggccga cgggcgaggc cgtgtgctgc cccgcgtcac gcccgccatc ctcctggtcc
     7501 tgctcgccct gaccggcccg tacctcgccg cccaccccct ggacaagccc gtcaccgccc
     7561 ccttcgctcc ccccggcgac ggggcgccgc tgggcgggga ccagctcggc cgcgatgtgc
     7621 tcagccgact gctccacggc ggcaccgccc tgatcggcag cgccctcctg gtcgccttcg
     7681 tcgtcaccct gctggccgcc ctgatcggct gtttcgccgt cctgcacccc gtcgtgggac
     7741 gcgccgtgga gcggaccgcc gacgtgttca tcctgctgcc gcccgtcctg ggcatcatgc
     7801 tcatcgcact ggcctggccc ggcggcggtc gatgggccgt catcagcgca gccaccgtcc
     7861 tgggcatccc gtacgccgta cgcgtcgtcg caggcgccgc cgcccccctg gccaccgccg
     7921 gatacgtcga agccgccctg gcgcgcgggg aaagcgtcac ctacaccgcc acccgcgaac
     7981 tcctgccgaa cctgcggggc accgtcctcg ccctgttcgg cctgcgcttc gtcgaagccg
     8041 tctacgtcat ctcgatggcc ggcttcctcc agatcggccc ccagcccccg gccgcggact
     8101 gggcgctgat gatccgcgag aacgccccgg gcatcctcct caacccgtgg gccgtcgtcg
     8161 cccccagcct gaccatcgcc ctgctcgcca tcagcgtcaa cctcgcggcc acctccctcg
     8221 cgccccgctc cgcacgcaag gcggtgacca ccccg
//
