BGC0001628: JBIR-78 biosynthetic gene cluster from Kibdelosporangium sp. AK-AA56
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Location: 1 - 35,856 nt. (total: 35,856 nt).
This entry is originally from NCBI GenBank LC217607.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
NRP
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0001628
Short description JBIR-78 biosynthetic gene cluster from Kibdelosporangium sp. AK-AA56
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
Loci NCBI GenBank: LC217607.1
Compounds
  • JBIR-78
  • JBIR-95
Species Kibdelosporangium sp. AK-AA56 [taxonomy]
References
Chemical products information
JBIR-78
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C40H55N7O12
Chemical database entries
NPAtlas
JBIR-95
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C39H55N7O13S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAX89995.1
  • orf1
 443 - 2476 (-) pyruvate dehydrogenase complex, E1 beta and E2 units
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  • BAX89996.1
  • orf2
 2547 - 3485 (-) pyruvate dehydrogenase complex, E1 alpha unit
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  • BAX89997.1
  • orf3
 3914 - 5191 (+) cysteic acid synthase
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  • BAX89998.1
  • orf4
 5223 - 12920 (+) Non-ribosomal peptide synthetase
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  • BAX89999.1
  • orf5
 12917 - 20539 (+) Non-ribosomal peptide synthetase
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  • BAX90000.1
  • orf6
 20600 - 32077 (+) Non-ribosomal peptide synthetase
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  • BAX90001.1
  • orf7
 32077 - 32286 (+) MbtH domain protein
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  • BAX90002.1
  • orf8
 32308 - 33528 (+) Cytochrome P450
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  • BAX90003.1
  • orf9
 34091 - 34762 (-) hypothetical protein
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NRP-specific information
Subclass N/A
Cyclic? no
NRP-synthases
Gene Modules
orf4
Module ?
Specificity: valine
Evidence for specificity:
  • Structure-based inference
  • Heterologous expression
Module ?
Specificity: aspartic acid / cysteic acid
Evidence for specificity:
  • Structure-based inference
orf5
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: leucine
Evidence for specificity:
  • Structure-based inference
orf6
Module ?
Specificity: glycine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: alanine
Evidence for specificity:
  • Structure-based inference
Module ?
Specificity: phenylalanine
Evidence for specificity:
  • Structure-based inference
Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Added NRP substrate specificities
Detailed domain annotation
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