LOCUS       BGC0001640             12133 bp    DNA     linear   BCT 04-OCT-2017
DEFINITION  Kocuria rosea strain s17 kocurin biosynthetic gene cluster, complete
            sequence.
ACCESSION   BGC0001640
VERSION     BGC0001640
KEYWORDS    .
SOURCE      Kocuria rosea
  ORGANISM  Kocuria rosea
            Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Kocuria.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-08 03:05:22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12133
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..177
                     /codon_start=1
                     /product="KocA"
                     /protein_id="ATG31918.1"
                     /transl_table=11
                     /translation="MDRKPTDLVDLPMDVFELEDQGMDITSLTAGHGMTEVGASTNCFC
                     YPCCSCSAPSSSA"
     source          1..12133
                     /db_xref="taxon:1275"
                     /mol_type="genomic DNA"
                     /organism="Kocuria rosea"
                     /strain="s17"
     misc_feature    1..12133
                     /note="kocurin biosynthetic gene cluster"
     subregion       1..12133
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="RiPP"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..12133
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             273..2927
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /product="KocB"
                     /protein_id="ATG31919.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 9.9e-34, bitscore:
                     105.5, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAQPQATLLPAEEAGPGDVYDVRISVVSAETLRALRFTRTSDA
                     MNELQRCRAVLASSSADALCALYAAIGVPGLDPQDKKELLRLKRALARGKMSGHRMGKS
                     LPLALTTELDRLEARHTDAQNALAQVELVFAADHDRTRALLAELARSPLVRNGILHSAP
                     SLEALMDTPTWAQSTASDKRATRLAQFVYRAAAKTSPFSTFTCTGRPGAEITMEATSVP
                     VPSATRLVRQLDGKIWALLLHNLEERPEIAAAWQLRPNPSLTFLPALDKFALLGPPPAE
                     ELRLLPDHPLIRRVAAMDPDPAPFLDWAKRLTGPRSAGSVEQDSGEVPMLVRAGVLHPV
                     APVSENTDQPLEDLLRWLDDHELTDTLPYAKILRRVSAALAPSPSPSLLDPVTLGNTHH
                     ALLEAVSDLVTGLGHDTRDLGADLQLVHESAVLESPVLTASIPSPEQLSTIAAARSWLS
                     VLDLKWPGRLAVATYADAVMPPAGSMPLLDLYRRVHHELRRGDGELARHLRTWFSAVPV
                     QPGPLTPTDQLDDTLRTLAQERQRCIQLATTAPEAGTTKLQLTEVIAHLTTRPEALRST
                     APAAVYLQATGAADSRWVVNVMHGGHGRGRARTDHLMRCAGLSPAPIHLPETPGTLPAE
                     YSGTHGSSLNARRPVLPAAIDYPYTPTVASDQQRIPVSRLHVRRTAGGLIELFDARCGT
                     RIEPAHVGMLADYQLPPLARFVERVFGDAYLLHPSTPPFASDLALDRLTDITRIPRVQI
                     DDVVIQRRRWIFPSAVLPRPRAGEHSTGYLHSLQEWFVAHELPPTAFVRAWGQELRGNK
                     VKSRKPMLLDLDSWWTVTELLRHSTGADFIVLDEALPDPFGRDLGAAAVELLVEVPAYR
                     INGASTDTGKGRA"
     CDS             2924..3862
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /product="KocC"
                     /protein_id="ATG31921.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 9.1e-47, bitscore:
                     149.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIDRTHESHHTPDASLDWLSLHLRCDGNTDEFLRGPIQMVLEE
                     LDARGTASSWFYLRYWEGGPHIRLRLLLPTHDHALAAELVREQTRPWLNAHDPEYPGAT
                     EAYAQIARSLATREAEHRELLPWQPHGRIWEQTYVPETAKYGAGASLQAFEQHFRDSSE
                     LALRVLRQQPSTTQVLSLATLLVLTGWARDDIGPTMQSRADLLDRWSSATALDRRPPAI
                     VRPDLMDRLFQRARTGQDPWSRQWSASLDELHRASSAAGVPAARWRNGADICHHLLCNR
                     LGLTLEQELTVRRSAWAVMDAAATAGAGISS"
     CDS             3859..4926
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /product="KocD"
                     /protein_id="ATG31922.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.4e-18, bitscore:
                     56.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWPTDPWWELYLMRWDADYAHVVDAVVRPLAQDGPLRDTKFFLD
                     TDWWRGPHVSVCFNASPQDKDALLARGLVPSTQKLLTALAPGRPVNPDHHQDLHERLGR
                     YERRPAPLFPWLTDGTVGLRPLLPREHDAVDKDMEHAVRACHLALKDLECELFHSLATG
                     QLRVHTYALDLLTAVAATFTDSDLRATYPSFASHSEAYLGSEAPEGTRTRWDQAYQQHR
                     ESVCERVRTIDHAAATSSLPAPIAITVEILRSVIDATHPLALFGGSALPGPAPTWQHSD
                     FHRDLGRNQQWQSSVRHNAWFARYRLVLNFAYLHLTKLGLSPHHRFYTCYLLTQAAQDL
                     TGTTASDILKGVARA"
     CDS             4919..6334
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /product="KocE"
                     /protein_id="ATG31920.1"
                     /sec_met_domain="PF00881 (E-value: 7.2e-17, bitscore: 51.2,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLAARPAPPTTRRHTDSWVRLALTPGVYLANGAQGAALIRWPR
                     SITLAGCNDATVEVLKELQHPEGIGIDADVLIGEIPASGPRESLLLQLMNDGWLVLSVH
                     GENGTLFAVHPRRRPPAWPDFPEAEYGLSRHTVLAPAGSAWSLEAPHSWCDLRFPDLDT
                     VHRCTAAPAQPTTALARRVLAWCGVLVDPQQEADQLKHRQWATHELWFHERSRRYGRER
                     SFGGTFWARGTFPPPPLRAPTSNMATELFEAVDPRVLRSQSMSLHEVMENRRSLRRHND
                     STPLTRAQLGEFLYRTARLRLAQEVDGVEYGSKPYPSGGSVYETEIYLLVRHVSGLAAG
                     LWRYDAQHHGLAPVREGLRDQHVAALLQEATHSSTVDSPPQVTVLMAPAFGRILWKYEQ
                     MGYAVMLKHVGVLMQTMYLVATDMGLAACAIGSGDSDLFAQATGLDPLECTTVGEFLLG
                     TAHPAEMFQERPA"
     CDS             6331..8007
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic"
                     /product="KocF"
                     /protein_id="ATG31923.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.2e-09,
                     bitscore: 26.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAGLVWSQTAVVTTHGWGVLIHSECGAQQVRGNGLQQPVEWLR
                     AQLAEPTPMEQLLAPLPPARRAPVERLVQALTDRGAITTFPEEPSLDKPASVELVVGAH
                     DFSRAAAHELGTLWQSSDIAYQCRDTAAESALPILDGTVQADGPAGQVTGFRLMLWDGQ
                     LWLGRFAGSEQERMTAAEEMTFHLLRSARKSDTGEAAVREHPWFPWLAQEVVQTHLSGA
                     EGVTECVRLSVTPFAKHRHRLIQEQRVPSAAAITASATALVEAPAQDPTDPLIVSRRCA
                     GLVDGVLSPVAPPEESELQQLPLQLSRCQVRLAAGVLETVLGHGWTLEQARGRAVAAAL
                     MTHGVSRLDPLVHMHPLFAPTGHDTGAQSAVVLPREQIERALAEANAAVSLGATADHGA
                     EVAATRLAAHLEMARGQRGMLSVDFPRTAQGADLLAIHQPCEELLVAVGLPFWLVAVQV
                     APGAVVMGVSAAHEEEAVHEAIRQALLHHQSRTAGNEAAAPRLYRRPPQAVYAPATQPP
                     DTLQKTLQEHGTVLTVPLSNGPSFDAALPHKTLVVLVPGGA"
     CDS             8011..9915
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     TIGR03604"
                     /gene_kind="biosynthetic"
                     /product="KocG"
                     /protein_id="ATG31924.1"
                     /sec_met_domain="TIGR03604 (E-value: 6.3e-98, bitscore:
                     317.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2.3e-71, bitscore: 230.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVLPALRSWSEHCHTTAQHLNDLWDLQEASTRWQLTVHTTGTP
                     SQDWTPAPNPEITVLLRPGAALVVACAPQHTGCPMCLITRHQLATPNLPEILEAEDQWT
                     SQDPTVTGLADPAMLARTIMAVARRLTEQPQCSPRRTMVRVDAHSLGLASHQYLPDPLC
                     QSCGRLPADSAEAATLTLEHRAKPRPDVYRYEHPAQRLEELKDLYVDEFCGLLHSLQRD
                     TQGGLAVAGALMKLRRHEWIEPGFGRSRNYETSEATAILEALERYGGVQPGGKQTVVKA
                     SLAQLGEDAVDPRRFGFHPQSTYLDESNSYRDFEPTDEHRWVWAYSFTQQRPLLVLESQ
                     AYYYVAHDIDTAPFVFEVSNGCALGSALEEAIFHGLLEVAERDAFLMTWYRRLALPQLR
                     PETAQHPEVQAQLTLIERETGYEIRLYDQTMENGIPSVWATALHPDPNATDAPAQVCAA
                     GAHPSLEQAALNALSEIGPFLNDFITRYPTLAARSEQMVDDPDLVRTMEDHSTLYGSPR
                     MRRHLQFLDQGPSISFAEAQGNSQQFTHESMADDVFEMVQRFRREGQDVLVVDQTTDEH
                     RAGGLFCVKILVTGSLTMTFGHHLRRTEGISRLATVPERLGLRSMIPEADTTLPHPFP"
     CDS             9933..10319
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thiopeptide: thio_amide"
                     /gene_kind="biosynthetic"
                     /product="KocH"
                     /protein_id="ATG31925.1"
                     /sec_met_domain="thio_amide (E-value: 4.6e-16, bitscore:
                     48.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFVVMAEWDLARHHTTMEDLRAWAHGPGATAYRGLPGVFLKSWY
                     SNPQEGIWGAVYLVEDPQALNPDRLPRTVGDHTGPIGTPPDRVRWNIMEDTVLGGSALT
                     TALGHDPTHAEAHQAPLPTADGPR"
     CDS             10316..12133
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 343.3; E-value:
                     4.4e-104)"
                     /gene_kind="transport"
                     /product="KocI"
                     /protein_id="ATG31926.1"
                     /transl_table=11
                     /translation="MTKERAPEAIMTTHPMDDHINTGTHPASHGPPRAPKGAFGDFLRV
                     IKSHRSSLIVVAVLSIAATVFGVAQPLMMQRMIDAAGQGDATRWVWWLVGVTVAEALLR
                     GAQSFLLQRTGEAFIGGLRHSLIARVLTLPMRSYTTTPKGEWISRLGSDTGQVRSIVTS
                     GLFELISAVLMFGAAIVLMVALDPLLFALTLTGVLLGAMGITIMGARMRRTSEITQAEV
                     ANMTSAADRALSSVTLVRASSATQDQIAKVTDYAQRAQASGVRMARIQAWVQPIMSLCI
                     QGAFLVVLAVGGLRVADGAMTVGELLAFIMYLFLLVMPVTQAMGAYTQIQLGLASYDRI
                     RQVLATDGERTGGTQYVHQIANSRGAAVILNGVHFRYDDQTVLQDVTFAVPTGSTTAIV
                     GPSGSGKSTVLSMLEGFIEPDGGTVHCLGHDLREVNLDTYRRAVAYVEQGAPAMGGTLA
                     DNLRIVKPDATEHDMRQALVAVGLEDLTLRQDAGLNMELGDNGSVLSGGERQRLAWARV
                     LLQDPELLLFDEPTASVDANTEGMLGEALEKVSRGRTTIIVAHRLATVVQADQIVVMDR
                     GAVLDVGTHHELVQRCTLYREFATHQLLV"
ORIGIN
        1 atggaccgta agcccactga tctcgtcgac cttccgatgg acgtgttcga gctggaggac
       61 cagggaatgg acatcacctc cctgaccgcc ggtcacggca tgaccgaggt cggcgcctcg
      121 acgaactgct tctgctaccc ctgctgctcc tgctcggctc cttccagcag cgcctgagct
      181 gacgtgcggt gaggtggttc agcggacgcg ttgagccacc tcacccgaca ggctttttac
      241 cctccacgtc gctccagtaa ggaaggtggg acatgtccac cgctcagccc caggccacgc
      301 ttctcccggc cgaggaagcc ggccccggcg acgtgtatga cgtgcggatc tccgtggttt
      361 ccgccgagac attgcgcgct ctgcggttca cccgcaccag cgatgccatg aacgagctcc
      421 agcggtgccg cgcagtgctt gcgtccagta gcgccgatgc cctatgcgcg ctctacgccg
      481 ccatcggcgt cccgggactg gacccgcagg ataaaaaaga gttgcttcgt ctcaaacggg
      541 ccctcgcccg cggcaagatg tcaggacacc gcatgggcaa gagccttcca ctggccttga
      601 ccactgagct tgatcgactc gaggctcggc acacggatgc ccagaatgcc ttggcacagg
      661 tagagctcgt ctttgccgcg gaccacgatc gtacccgggc cctgctggct gagctggccc
      721 gttcgccctt agtgcgcaac gggatcttgc actcggcgcc cagcctggaa gccctcatgg
      781 acacacccac gtgggctcaa tcaacggcct cagacaagcg cgccacccgc ctcgcccagt
      841 tcgtctaccg tgctgcggct aagaccagcc ctttctccac gttcacctgc actggacgcc
      901 ccggcgcaga gatcaccatg gaggcaacct ccgtccccgt cccatccgcg actcggctcg
      961 tgcgccagct cgacggcaag atctgggcgc tgcttctcca taacctcgag gaacgtcccg
     1021 agatcgccgc agcctggcag ctgcggccga acccgtcatt gaccttcctt cccgcccttg
     1081 acaagttcgc gctgctcggc ccgccacctg ctgaggagct gcgtctgctt cccgaccatc
     1141 cgctgatccg tcgggttgcc gcaatggacc ctgatccggc cccgttcctc gactgggcaa
     1201 agcgcctcac gggcccccgc agcgctggca gtgttgagca ggacagcggg gaagtaccca
     1261 tgctggtgcg ggccggtgtg ctccacccgg tggctccggt gtccgagaac acggatcaac
     1321 cacttgagga cctcctccgg tggcttgacg atcatgagct gaccgacacc ctcccgtatg
     1381 ccaagatcct ccgtcgggtg agcgctgcgc tggcgccgtc cccgtccccg tccctgctgg
     1441 atcctgtgac cttgggcaac actcaccacg ccctactgga ggccgtatcc gacctggtca
     1501 ccgggcttgg ccacgacacc cgggacctcg gagcggacct gcaacttgtg cacgaatccg
     1561 ccgtgctgga atccccggtt ctcaccgcta gcatcccatc accggagcag ctgtcgacga
     1621 ttgcggccgc acggtcgtgg ttgtcggtac tggacctcaa atggccgggc cgactggccg
     1681 tggctaccta cgctgatgcc gtcatgcccc ctgcaggctc catgccactg ctggatctgt
     1741 accggagggt tcatcacgaa ctgcgccgcg gtgacggaga actcgcccgc catctgcgca
     1801 catggttttc ggccgttccg gtgcaaccgg gaccgctcac ccctaccgac cagctcgacg
     1861 acactcttcg cactctcgcc caagaacggc aacggtgcat ccagttggcc accacggccc
     1921 cggaggcggg cacgacgaag ctgcagctaa ccgaggtgat cgcccatcta actacgaggc
     1981 cggaggcttt gcgctccact gcacccgcgg ccgtgtacct acaggccacc ggggctgctg
     2041 atagccgctg ggtggtcaac gtgatgcacg gcggacacgg gcgaggccgc gcccgcaccg
     2101 atcacctcat gcggtgcgcc ggcctgagcc cggccccaat ccacctaccc gaaacccccg
     2161 gcaccctgcc ggctgagtac agcggaacgc acggctcatc gctaaacgcc cgccgccctg
     2221 tcctgcccgc ggccatcgat tatccctaca cccctactgt cgcatcggac cagcaacgga
     2281 tccccgtgag tcgtttgcac gtccgccgca cggctggggg cctgatcgaa ctctttgatg
     2341 cccgctgcgg cacacgcatc gagccggccc atgtaggcat gctcgccgac taccaactgc
     2401 cgcctctagc gaggttcgtg gaacgggtgt tcggggatgc ctacctactg catcccagca
     2461 cgcccccttt cgcctccgat ttggcccttg accggcttac cgacatcacc cggatccccc
     2521 gggtgcaaat cgacgatgtt gtcatccaac gccgtcgatg gatcttcccg tccgctgtgc
     2581 ttccccgacc ccgggccggt gagcacagca ctggctatct gcacagcttg caggagtggt
     2641 ttgtcgccca cgagttgccg cccaccgcat tcgtccgggc ctgggggcag gagttgcgcg
     2701 gaaacaaggt caagtctcgt aaaccgatgc tcttggacct cgactcctgg tggacggtga
     2761 cggaactgct gcgccatagc accggggcgg acttcatagt gctcgacgag gcactgccgg
     2821 accccttcgg ccgcgacctt ggagcggcgg cggtcgagct gctcgtcgag gtcccggcgt
     2881 accgcatcaa cggcgcgagc acagacacgg gaaagggacg cgcatgacag ctatcgaccg
     2941 gacacacgag tctcaccaca cccctgacgc ttccctggac tggctttccc tgcacctgcg
     3001 ctgtgacggc aacactgatg agttcctccg cggtcctatc caaatggtgc ttgaggagct
     3061 ggatgcgcgc ggtaccgcct catcgtggtt ctacttacgg tactgggagg gaggaccaca
     3121 catccgccta cgtctactgc tcccgaccca tgaccatgct ctggcagcag agttagtgcg
     3181 ggagcagacc cgcccgtggc tgaacgccca cgatcccgag tacccgggtg ctacggaggc
     3241 ctatgcgcag atcgcccgca gcttagccac gcgagaagcg gaacatcgcg agctgctgcc
     3301 ctggcaaccc cacgggcgga tctgggaaca aacctacgtt cccgagactg ccaaatacgg
     3361 ggccggcgcc tcgctgcaag ccttcgaaca gcattttcgg gacagctccg agctggcgct
     3421 gcgcgtgtta cgccagcaac cgtcgaccac ccaggtgctc tccctcgcga ctttgctggt
     3481 gctcaccggg tgggcgcgcg atgacatcgg ccccaccatg cagtcccgcg cggacctgct
     3541 cgaccgctgg agcagcgcca cggccctgga ccggcggccc cccgctatcg tgcgcccgga
     3601 tctgatggac aggctattcc agcgtgcccg gaccggtcag gacccctggt ctcgccagtg
     3661 gtcggcttcc ctcgacgagc tgcaccgggc cagctctgca gccggagtcc ccgccgcgcg
     3721 gtggcgcaac ggggccgaca tctgccacca cctgctgtgt aaccgtctgg gtctgaccct
     3781 ggagcaggag ctgaccgtgc gccgtagcgc ctgggcggtc atggacgcgg ccgcgacggc
     3841 cggggcaggt atcagctcat gacatggccc acggacccgt ggtgggagct ttacctcatg
     3901 cgctgggacg ccgattacgc ccacgtcgtc gacgcggtgg tgcgacccct ggcccaggac
     3961 gggcccctgc gtgacaccaa gttcttcctg gacaccgatt ggtggcgggg cccgcacgtg
     4021 tccgtctgct tcaacgcctc acctcaggac aaggacgcac tactcgctcg cggattggtg
     4081 cccagcaccc agaagttgtt gacggcgctt gccccgggcc ggcccgtgaa ccccgaccac
     4141 caccaggacc tgcacgaacg actgggtcgc tatgaacgtc gcccggctcc gctgttcccg
     4201 tggctaaccg acggcacagt ggggctgcgt cccctgctcc cgcgggaaca cgacgcggtg
     4261 gacaaggaca tggagcacgc cgtacgtgct tgccacctgg ccttgaaaga cctcgagtgc
     4321 gagctcttcc actcactggc caccggacag ttgcgggtgc acacctatgc gctggacctg
     4381 ctcactgccg tcgccgccac tttcaccgac tccgacctgc gagccaccta cccttctttc
     4441 gcttcgcact ccgaggcgta cttgggctca gaggcgcccg agggcacccg cacccgctgg
     4501 gatcaggcct accaacaaca ccgggagagc gtgtgcgagc gggtgcgcac catcgaccac
     4561 gcagcggcca cgtcgtcgtt gccagcgccc atcgcgatca ccgtggagat cctccgctcg
     4621 gtcattgatg ccacgcaccc tctggcgctg ttcggaggta gcgcgctgcc gggcccggcg
     4681 cctacctggc agcattccga cttccaccgt gaccttgggc gcaaccagca gtggcagagc
     4741 agcgtacggc acaatgcctg gttcgcccgc taccggctcg tgctcaactt cgcctatttg
     4801 cacctcacca agctgggcct cagccctcac caccggttct acacctgtta tctgctcacc
     4861 caagcagccc aggacctgac cggaaccacc gcatccgaca ttctgaaagg cgttgcccgt
     4921 gcctgatctc gccgctcgcc ccgccccgcc gacgactagg cgtcacaccg actcctgggt
     4981 gcgcttggcc ctgacaccag gcgtctacct ggccaatggc gcccagggag ctgctctcat
     5041 tcggtggccc cgcagcatca ccctcgcggg gtgcaacgat gccaccgtcg aggttctgaa
     5101 agagctccag cacccggagg gcatcgggat cgacgcggac gtcctcatcg gtgagatccc
     5161 ggcctcgggc ccccgggaga gcctcctcct ccaactgatg aatgacggct ggctggtgct
     5221 ctccgtgcac ggggagaacg ggaccctatt cgccgtccac ccccgccgcc gacccccagc
     5281 atggccggac ttcccagaag ctgagtatgg actgtcccgg cacacggtcc tagcccccgc
     5341 cgggtccgcc tggtccttgg aagctccgca ttcctggtgt gacctgaggt tcccggacct
     5401 ggacacggtg caccgctgca ccgctgcgcc ggcgcagccg acgacggcac ttgctcgcag
     5461 ggtcctcgcc tggtgcggtg tcctggtgga tccgcagcag gaggccgacc agctcaagca
     5521 ccggcagtgg gctacccacg aactgtggtt ccacgaacgc tcccgacgtt acggccgtga
     5581 gcgcagcttc ggtggaacat tctgggcccg tggaaccttt cctccgccgc cgttgcgcgc
     5641 cccaacctcc aatatggcca ccgagctgtt cgaggcggtg gacccccggg tactgcgctc
     5701 ccagtcgatg agcctgcacg aagtaatgga gaaccgccgt tcccttcggc gtcacaacga
     5761 ctccacccct ttgactcgtg cgcaactagg tgaattcctc tatcgcacag cacgactgcg
     5821 cctggcgcag gaggtcgacg gggtggagta cggcagcaaa ccgtatccgt cggggggatc
     5881 ggtgtatgag acggagatct acttgctcgt gcgccacgtc agtggcctgg cagccggact
     5941 gtggcgctac gatgcgcagc accacggctt ggcccccgtg cgggaaggtc tgcgggatca
     6001 gcacgtggcg gcgttgctgc aggaggccac gcactcctcc acggtggact cccctcctca
     6061 ggtgacggtg ctcatggccc cggccttcgg gcggattctg tggaaatacg agcagatggg
     6121 ctacgccgtg atgctcaaac acgtcggggt gctgatgcaa accatgtatc tggtggccac
     6181 tgacatgggc ctggccgcgt gtgcgattgg cagcggcgac agcgacctgt tcgcccaggc
     6241 cacggggctg gatcctttgg aatgcacgac ggtcggggaa ttcctcctcg gtacagctca
     6301 cccggcggaa atgttccagg agcggcccgc atgagcgccg caggcctcgt ctggtctcag
     6361 acagccgtcg tgaccaccca tggttggggt gtgctgatcc acagtgagtg cggggcgcag
     6421 caggtgcggg gcaacgggtt gcagcaaccg gtggagtggt tacgtgccca gctagccgaa
     6481 ccgaccccga tggagcagct actggctcct ctgcccccag cccgcagggc gccggtggag
     6541 cggctggtcc aggccctcac agaccgtggg gcgatcacga cgttccccga ggaaccttcc
     6601 ctggacaagc ccgccagcgt tgagcttgtt gtgggtgccc atgacttctc ccgcgccgcg
     6661 gcccatgaac tgggcacgct gtggcaatca agcgatatcg cctaccagtg ccgtgacacc
     6721 gcggcggaat cggcattgcc tattctggac ggaaccgtgc aggcggatgg acctgccggg
     6781 caggtgacgg gtttccggct gatgttgtgg gatgggcagc tgtggttggg gcggttcgcc
     6841 ggctcggaac aggaacgaat gacggctgcg gaagaaatga cctttcacct gctccgtagc
     6901 gcccgaaaga gcgacaccgg agaagctgcg gtacgggaac atccgtggtt tccctggctg
     6961 gcccaagaag tagtgcagac ccacctgagc ggggccgagg gggtcacgga gtgcgtgcgg
     7021 ctgagcgtca ccccgttcgc gaagcaccgg caccggctca tccaagagca gcgtgtccct
     7081 tctgccgccg ctattacagc atccgctaca gccttggtcg aggcacccgc gcaggacccc
     7141 acggaccccc tgatcgtttc ccgccggtgc gcagggctag tggacggtgt gctcagcccg
     7201 gtggcccccc cggaggaatc ggagttgcaa cagttgcctc tgcagctatc acggtgccag
     7261 gtgcgccttg ccgccggggt gctcgagacc gtgctgggtc acggctggac cctggaacaa
     7321 gcgcggggcc gagccgtggc agctgcactc atgacccatg gcgtgtcccg cttggacccg
     7381 ctcgtgcaca tgcatccgct attcgcccct accgggcacg acaccggtgc ccaatccgct
     7441 gttgtcctgc cccgcgagca gatcgagcgc gcgctggcgg aggctaacgc tgccgtgtct
     7501 ctgggcgcca ccgccgacca cggcgccgag gtggccgcga cccggctggc cgcccaccta
     7561 gagatggccc gcgggcagcg tgggatgctg tccgtagact tcccccgcac ggcgcagggc
     7621 gctgatctac tggcgatcca tcaaccgtgc gaggaactgc tggtagcggt gggactgccg
     7681 ttctggttgg tcgcggttca agtagccccg ggagcagtgg tgatgggcgt gtcggcagcc
     7741 catgaggaag aagcagtgca cgaggccatc cgccaggccc tcctgcacca ccagtcccgg
     7801 acggccggca acgaggctgc cgcaccccgg ctctaccgga ggccaccgca agcggtctac
     7861 gcgccggcta cccaaccccc ggacaccttg caaaagactc tgcaggaaca tggcacggtc
     7921 ctgacggtgc cgttatccaa cggtccgtcc ttcgacgccg ccctaccgca caaaaccctc
     7981 gtcgttctcg tccccggagg tgcctagatt atgaccgtcg tcctgcctgc gctacggagc
     8041 tggtccgagc attgccacac caccgctcag catctcaacg acctgtggga ccttcaagag
     8101 gcgagtacac ggtggcaact gacggttcac accaccggaa cgcccagcca ggactggacc
     8161 cctgcgccca accccgaaat cacagtccta ttgcgccccg gagccgcgct cgtcgtagca
     8221 tgcgccccgc agcacacggg ctgtcccatg tgtctcatca cccgccacca actggccaca
     8281 ccaaacctcc cggaaatcct cgaggccgaa gaccaatgga cctcccagga cccgactgtc
     8341 accggactgg cggacccggc aatgctcgcc cggacaatca tggccgtagc gcgccggctc
     8401 accgaacaac cccagtgctc acctcgacgc accatggtcc gggtcgatgc ccacagtttg
     8461 ggcctggcct cgcaccaata cctacccgac ccgttgtgcc aatcctgtgg gcggttgccc
     8521 gccgacagcg ctgaggcggc caccctcacc ttggaacacc gagccaagcc gcgccccgac
     8581 gtctaccgct atgagcatcc tgcccagcgc ttggaggagt tgaaggatct ctacgtggac
     8641 gagttctgcg gccttctcca ctccctccag cgtgacaccc aaggtgggct ggcagtggct
     8701 ggggcgttga tgaagctgcg tcgccacgaa tggatcgaac ccggcttcgg ccgcagccgt
     8761 aactacgaaa ccagcgaggc caccgcgatt ctggaagcct tggaacgcta cggtggggtc
     8821 cagcctggcg ggaaacagac ggtggtgaaa gcctccctgg cgcaactggg cgaggacgcc
     8881 gtggatccgc gccgattcgg cttccaccca caaagcacct acctcgacga aagcaattcc
     8941 tatcgggact tcgaacccac cgacgagcac cgctgggtgt gggcatattc cttcacccag
     9001 cagcgaccgc tgctagtgct ggaatcccag gcctactact acgtcgccca tgacatcgat
     9061 acggctccct tcgtgttcga agtctccaac gggtgcgcgc tcggttcggc actcgaggag
     9121 gcgatcttcc atgggctgct ggaggtcgcc gaacgcgacg cgttcctgat gacctggtat
     9181 cggcgcctgg ctctgcccca gttgcgcccc gagaccgccc aacacccaga ggtgcaggcg
     9241 caactaactc tcatcgagcg cgaaaccggc tacgaaatcc gcctctacga ccagaccatg
     9301 gaaaatggca ttccctcagt ctgggccact gccctccatc cagatccgaa cgcgaccgac
     9361 gctcccgcgc aggtgtgcgc cgccggcgcg cacccctcct tggagcaggc cgcgctcaat
     9421 gccctcagcg agatcggtcc tttcctcaac gacttcatca cccggtatcc cactctggcc
     9481 gctcggtccg aacagatggt ggatgatccc gatctggtgc ggactatgga ggaccactcc
     9541 accctctacg gttccccccg tatgcgccgc catctgcagt ttctcgatca gggaccctcg
     9601 atttccttcg ccgaggccca aggaaattca caacagttca cccatgagtc catggccgat
     9661 gacgtcttcg aaatggtcca gcgcttccgc cgcgagggac aagacgtgct ggtggtcgac
     9721 cagaccaccg acgaacaccg cgccggtgga ctgttctgcg tcaagattct agtgaccggt
     9781 agtctcacca tgacctttgg ccatcatcta cggcgcactg agggtatttc caggctggcc
     9841 accgtgccgg aaagactagg gctgcgatcg atgatcccgg aggcggacac aaccctgccc
     9901 caccccttcc cttgagccag aaagacatcg atatgcgctt cgtagtcatg gccgagtggg
     9961 acctggcccg tcaccacacc actatggaag atttgcgggc ctgggcccat ggacctggcg
    10021 ctaccgccta tcgcggtttg cccggtgtgt tcctgaaatc ctggtactcc aacccccaag
    10081 aaggcatctg gggagcggtc taccttgtgg aagaccccca ggcactgaac cccgaccggt
    10141 taccccgcac cgtcggagac cacacaggac ccattggcac tcctccggac cgggtccgct
    10201 ggaacatcat ggaagatacc gtcctaggcg ggtcagctct aaccactgcc ctgggacacg
    10261 accccacaca cgcggaggcg catcaagccc ccctgcctac agcggacggg ccacgatgac
    10321 taaagagcga gcaccggagg ccatcatgac cacacacccc atggacgacc acatcaacac
    10381 cggcactcat cctgcctcgc atggcccgcc gcgggcgccg aagggagcct tcggtgactt
    10441 tttacgggtc attaagtcac atcggtccag ccttatcgtg gtcgccgttc tttctatcgc
    10501 tgccactgtt tttggcgtag cccaaccact catgatgcaa cggatgatcg acgccgccgg
    10561 tcaaggggat gccactaggt gggtgtggtg gctcgtgggc gtcaccgttg ctgaggctct
    10621 tctgcgaggg gcgcaatcct tcctcctgca acgcacgggc gaggccttca ttggaggatt
    10681 acgccactca ctcatcgccc gagtactcac tctcccgatg cgcagttaca ccaccacacc
    10741 taaaggtgag tggatcagcc ggctcggctc cgacaccgga caagtgcgca gcattgtcac
    10801 ttctggacta ttcgaactaa tttccgccgt tctcatgttt ggtgccgcaa ttgtgctcat
    10861 ggtcgcactt gaccctctgc tgtttgccct caccctcaca ggggttcttc tcggtgccat
    10921 gggcatcacc atcatgggcg cacgcatgcg acgcaccagc gaaatcactc aggccgaagt
    10981 cgcgaatatg acctccgccg ccgaccgcgc cttgagctct gtcaccctgg ttagagccag
    11041 ctcagctaca caggaccaaa tcgctaaagt caccgactac gcccagcgag cccaagcttc
    11101 tggggtgagg atggcccgca tccaagcctg ggtgcaaccc atcatgtctt tatgcatcca
    11161 aggcgctttt ctcgtcgttc ttgccgttgg tgggctccgc gtagccgacg gggccatgac
    11221 cgttggcgag ctcctggcct tcatcatgta cctcttcctg cttgttatgc ccgtgaccca
    11281 agcaatgggg gcctacacgc agatccaact cggcctcgcc tcctacgacc gaatccgcca
    11341 ggtactggcc actgacggcg aacgcactgg cggcacccaa tacgtccacc agatcgcgaa
    11401 ttcccgcggc gctgcagtca ttctgaacgg cgtccatttc cgctatgacg accaaacggt
    11461 cctccaagat gtcaccttcg cagtgcccac cggttcgaca acggccatcg tcggaccttc
    11521 cggatccgga aaatccacgg tgctctccat gctcgaagga tttatcgaac ccgatggcgg
    11581 aactgtccac tgcctcgggc atgacttacg tgaagttaat ttggacactt accgacgagc
    11641 agtcgcctac gtcgagcaag gcgctcctgc tatggggggc accctggcgg ataaccttcg
    11701 gatcgtcaaa ccagacgcta ccgaacacga catgcgccag gcgctcgtag ctgtgggcct
    11761 agaggattta acactgcgcc aggacgccgg tttgaacatg gagctgggtg acaacggatc
    11821 ggtgctctca ggtggtgagc gccagcgatt ggcttgggct cgagtgttgc tccaggatcc
    11881 tgagctgttg ctctttgatg aaccgacggc cagcgttgat gcgaacaccg aaggcatgct
    11941 gggagaggcg ctcgaaaagg tctcacgcgg taggacaacg attatcgtgg cacaccgttt
    12001 ggccacggtg gtccaagcgg atcaaatcgt ggtgatggac cggggtgctg tattggacgt
    12061 tggcacgcac cacgaactgg ttcagcggtg cacgctttat cgtgaatttg ctacccatca
    12121 attgctggtc tga
//
