BGC0001646: lagriamide biosynthetic gene cluster from Burkholderia gladioli
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Location: 1 - 99,474 nt. (total: 99,474 nt).
This entry is originally from NCBI GenBank MH171092.1.

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core biosynthetic genes
additional biosynthetic genes
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TTA codons
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General
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NRPS/PKS domains
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General information about the BGC
MIBiG accession BGC0001646
Short description lagriamide biosynthetic gene cluster from Burkholderia gladioli
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRP
  • Polyketide
Loci NCBI GenBank: MH171092.1
Compounds
  • lagriamide
Species Burkholderia gladioli [taxonomy]
References
Chemical products information
lagriamide
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AXA20086.1
 1190 - 1714 (-) sigma-70 RpoE
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  • AXA20087.1
 1915 - 2109 (+) competence protein ComEC
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  • AXA20088.1
 2205 - 2315 (+) transposase
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  • AXA20089.1
 2828 - 3118 (+) hypothetical protein
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  • AXA20090.1
 3132 - 13793 (+) hybrid trans-AT PKS/NRPS LgaA
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  • AXA20091.1
 13790 - 33007 (+) hybrid trans-AT PKS/NRPS LgaB
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  • AXA20092.1
 33004 - 53403 (+) trans-AT PKS LgaC
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  • AXA20093.1
 53400 - 57239 (+) trans-AT PKS LgaD
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  • AXA20094.1
 57289 - 58401 (+) acyltransferase LgaE
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  • AXA20095.1
 58398 - 59783 (+) enoylreductase LgaF
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  • AXA20096.1
 59909 - 86623 (+) trans-AT PKS LgaG
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  • AXA20097.1
 86717 - 87112 (+) nuclear transport factor 2 (NTF2)-like protein LgaL
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  • AXA20098.1
 87147 - 88520 (+) MATE family efflux transporter LgaH
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  • AXA20099.1
 88580 - 89593 (+) acylhydrolase LgaI
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  • AXA20100.1
 90318 - 90704 (+) transposase
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  • AXA20101.1
 90836 - 92020 (+) cytochrome P450 LgaJ
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  • AXA20102.1
 92083 - 92817 (+) LgaM
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  • AXA20103.1
 92859 - 93680 (+) ketoreductase LgaK
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  • AXA20104.1
 93904 - 95667 (-) phosphoenolpyruvate-protein phosphotransferase
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  • AXA20105.1
 95865 - 97904 (+) squalene--hopene cyclase
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  • AXA20106.1
 98026 - 98871 (+) all-trans-phytoene synthase
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  • AXA20107.1
 98927 - 99394 (+) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.4
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Merged annotations from duplicate entry BGC0001946
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Detailed domain annotation
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